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Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology

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https://www.readbyqxmd.com/read/27889322/landmark-reading-alterations-in-patients-with-gastro-oesophageal-reflux-symptoms-undergoing-diagnostic-gastroscopy
#1
Mustafa Kaplan, Alpaslan Tanoglu, Yusuf Serdar Sakin, Taner Akyol, Kemal Oncu, Muammer Kara, Yusuf Yazgan
BACKGROUND AND STUDY AIMS: There is still a debate about the exact measurement of the oesophagogastric junction and the diaphragmatic hiatus among clinicians. The aim of this study was to investigate the differences between landmark readings of gastroscopy on intubation and extubation, and to correlate these readings with a gastro-oesophageal reflux questionnaire. PATIENTS AND METHODS: 116 cases who underwent diagnostic gastroscopy between January 2013 and June 2013 were included in this study...
November 23, 2016: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://www.readbyqxmd.com/read/27686263/dna-repair-genes-polymorphisms-and-risk-of-colorectal-cancer-in-saudi-patients
#2
Rehab A Karam, Bilal O Al Jiffry, Mohamed Al Saeed, Tamer M Abd El Rahman, Mohamed Hatem, Mona G Amer
BACKGROUND AND STUDY AIMS: Polymorphisms in the DNA repair genes may influence individual capacity to repair DNA damage, which may be associated with increased genetic instability and carcinogenesis. Our aim was to evaluate the relation of genetic polymorphisms in 2 DNA repair genes, XPD Lys751Gln and XRCC1 (A399G), with colorectal cancer (CRC) susceptibility. We further investigated the potential effect of these DNA repair variants on clinicopathological parameters of CRC patients. PATIENTS AND METHODS: Both XPD and XRCC1 polymorphisms were characterised in one hundred CRC patients and one hundred healthy controls who had no history of any malignancy by polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP) method and PCR with confronting two-pair primers (PCR-CTPP), using DNA from peripheral blood in a case control study...
September 2016: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://www.readbyqxmd.com/read/27671863/ph-multichannel-impedance-monitoring-in-patients-with-laryngo-pharyngeal-reflux-symptoms-prediction-of-therapy-response-in-long-term-follow-up
#3
Simon Nennstiel, Mack Andrea, Mohamed Abdelhafez, Bernhard Haller, Roland M Schmid, Monther Bajbouj, Valentin Becker
BACKGROUND AND STUDY AIM: Optimal therapy concepts in patients with laryngo-pharyngeal reflux (LPR) are still under discussion. Aim of this study was to evaluate long term symptom relief according to results in combined pH/multichannel impedance (MII) monitoring to predict therapy response and symptom relief during long term follow-up. PATIENTS AND METHODS: In patients with predominant LPR symptoms, pH/MII monitoring and subsequent proton pump inhibitor (PPI) therapy were evaluated retrospectively after a minimum follow-up period of 36months...
September 2016: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://www.readbyqxmd.com/read/27665525/standard-triple-therapy-versus-sequential-therapy-for-eradication-of-helicobacter-pylori-in-treatment-na%C3%A3-ve-and-retreat-patients
#4
Adnan Abuhammour, Asad Dajani, Mohammed Nounou, Mohammed Zakaria
BACKGROUND AND STUDY AIMS: Untreated Helicobacter pylori infection causes increased risk of gastric cancer, GI morbidity and mortality. Standard treatment for eradication of Helicobacter pylori infection, is the triple therapy which consists of a proton pump inhibitor; together with two antibiotics (amoxicillin 1000mg with clarithromycin 500mg or metronidazole 400mg) given twice daily for 7-14days. Recent evidence revealed, that cure rates of Helicobacter pylori infection with triple therapy had fallen below satisfactory targets...
September 2016: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://www.readbyqxmd.com/read/27658328/a-case-of-hepatic-portal-venous-gas-after-colonoscopy
#5
Tevfik Solakoglu, Sevil O Sari, Huseyin Koseoglu, Murat Basaran, Mustafa Akar, Semnur Buyukasik, Osman Ersoy
Hepatic portal venous gas (HPVG) is a rare radiologic finding that is usually precipitated by intestinal ischaemia, intra-abdominal abscesses, necrotising enterocolitis, abdominal trauma, infectious enteritis, and inflammatory bowel disease. In this study, we present a case of HPVG in a 66-year-old female patient who underwent colonoscopy for evaluation of haematochezia and a review of the literature focused on HPVG following colonoscopy.
September 2016: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://www.readbyqxmd.com/read/27658327/liver-research-in-the-international-space-station
#6
Hanaa Gaber, Akram Abdellatif
No abstract text is available yet for this article.
September 2016: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://www.readbyqxmd.com/read/27658326/acute-vanishing-bile-duct-syndrome-after-the-use-of-ibuprofen
#7
Ahmet Basturk, Reha Artan, Aygen Yılmaz, Mustafa T Gelen, Ozgur Duman
We present a case report of a 7-year-old patient who developed toxic epidermal necrolysis (TEN) and vanishing bile duct syndrome (VBDS) after oral ibuprofen intake. Acute VBDS is a rare disease with unknown aetiology, often presenting with progressive loss of the intrahepatic biliary tract. TEN is an immune complex-mediated hypersensitivity reaction involving the skin and mucosa, which is induced by drugs or infectious diseases, sometimes leading to systemic symptoms. The patient in this case report was treated with supportive care, a steroid and ursodeoxycholic acid, with complete recovery observed by the end of the 8th month...
September 2016: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://www.readbyqxmd.com/read/27651136/highlights-from-gastro-update-europe-prague-april-29-30-2016
#8
Guido N J Tytgat
No abstract text is available yet for this article.
September 2016: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://www.readbyqxmd.com/read/27651135/follicular-lymphoma-of-the-caecum-resected-endoscopically
#9
Yuji Eso, Yoshitaka Nishikawa, Atsushi Takai
Colorectal follicular lymphomas, primary or secondary, are rare. Magnifying endoscopy with narrow-band imaging is useful in the diagnosis of colorectal follicular lymphoma. In addition, immunohistochemistry is essential in differentiating follicular lymphoma cells from lymphoid follicle hyperplasia based on the presence of Bcl-2 expression. We herein report a rare case of follicular lymphoma of the caecum, presenting as a small polyp that was resected endoscopically.
September 2016: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://www.readbyqxmd.com/read/27633526/sigmoid-volvulus-after-caesarean-section
#10
Asem Ahmed Elfert, Eslam Saber Esmail, Ibrahim Shibl S Eldin
No abstract text is available yet for this article.
September 2016: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://www.readbyqxmd.com/read/27591102/quality-of-life-in-patients-with-colorectal-cancer-in-iran
#11
Mohsen Akhondi-Meybodi, Sara Akhondi-Meybodi, Mahmood Vakili, Zahra Javaheri
BACKGROUND AND STUDY AIMS: Colorectal cancer is a major health problem primarily affecting the quality of life (QoL) of both patient and family. With the advances in surgery and novel chemotherapeutic drugs and modalities, survival has increased and the QoL has improved. The aim of this study was to assess QoL in patients with colorectal cancer taking the situation in the Iranian city Yazd from 2006 to 2011 as an example. PATIENTS AND METHODS: This study was conducted on 120 patients who were diagnosed with colorectal cancer within the 5-year period of the study...
September 2016: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://www.readbyqxmd.com/read/27567189/immunohistochemistry-in-the-diagnosis-of-dysplasia-in-chronic-inflammatory-bowel-disease-colorectal-polyps
#12
Ehsen B Brahim, Ali Mrabet, Raja Jouini, Wafa Koubaa, Rimel B Sidhom, Hela Elloumi, Aschraf Chadli
BACKGROUND AND STUDY AIMS: Development of cancer is the most significant complication in inflammatory bowel disease (IBD). Distinguishing true dysplasia from reactive atypia in polyps is difficult, leading sometimes to the unsatisfactory diagnosis of "indefinite for dysplasia". Therefore, there is a need for the development of markers that can help improve diagnosis. We evaluated the diagnostic value of the expression of AMACR, Ki67 and p53 by immunohistochemistry in the diagnosis of dysplasia in polyps developed on IBD...
September 2016: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://www.readbyqxmd.com/read/27502622/arab-journal-of-gastroenterology-a-rising-star
#13
EDITORIAL
Abdel Meguid Kassem
No abstract text is available yet for this article.
June 2016: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://www.readbyqxmd.com/read/27426959/evaluating-the-effect-of-infliximab-on-the-healing-of-left-colonic-anastomosis-in-the-presence-of-intra-abdominal-sepsis
#14
Alper Sozutek, Sefa Ozyazici, Tahsin Colak, Suleyman Cetınkunar, Oktay Irkorucu, Onur Bobusoglu, Ahmet Cennet
BACKGROUND AND STUDY AIMS: Infliximab (IFX) is a chimeric anti-TNF-α body which is effectively used in the treatment of inflammatory bowel diseases and a variety of autoimmune diseases. The effect of IFX on the healing of intestinal anastomosis has been evaluated in several studies, however with conflicting results. Furthermore, the effect of IFX on colonic anastomosis in sepsis has not been evaluated to date. In this study, we aimed to investigate whether IFX has an adverse effect on the healing process of colonic anastomosis either under normal or septic condition...
June 2016: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://www.readbyqxmd.com/read/27426958/the-role-of-vascular-endothelial-growth-factor-634-g-c-and-its-soluble-receptor-on-chronic-liver-disease-and-hepatocellular-carcinoma
#15
Neneng Ratnasari, Siti Nurdjanah, Ahmad H Sadewa, Mohammad Hakimi
BACKGROUND AND STUDY AIMS: The single nucleotide polymorphism (SNP) of the vascular endothelial growth factor (VEGF) gene -634 G/C (rs2010963) influences the progression of hepatocellular carcinoma (HCC). There have been no studies on the role of VEGF SNP -634 G/C in chronic liver disease (CLD). The aim of the present study was to analyse the correlation between VEGF SNP -634 and the clinical severity of CLD and HCC. PATIENTS AND METHODS: A cross sectional study was conducted on 182 subjects (46 HCC, 39 liver cirrhotic/LC, 38 chronic hepatitis/CH; and 57 healthy subjects)...
June 2016: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://www.readbyqxmd.com/read/27426957/evaluation-of-iron-deficiency-anaemia-for-gastrointestinal-causes-in-patients-without-gi-symptoms-in-high-prevalent-gi-malignancy-zones
#16
Showkat A Kadla, Nisar A Shah, Muzafar A Bindroo, Bilal A Khan, Adil Farooq, Wajeed Yousf, Bilal A Wani
BACKGROUND AND STUDY AIMS: Gastric cancer is highly prevalent in Kashmir, as are lower gastrointestinal (LGI) malignancies. Colonic cancer, gastric cancer, and coeliac disease are the most important gastrointestinal (GI) causes of iron deficiency anaemia (IDA) worldwide. Approximately 9% of patients with IDA present with a suspicious lesion in the GI tract upon examination. However, the absence of GI symptoms and a possible lesion accounting for blood loss in IDA have not been studied in this zone with a high prevalence of GI malignancy...
June 2016: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://www.readbyqxmd.com/read/27397412/haemophagocytic-lymphohistiocytosis-presenting-as-neonatal-liver-failure-a-case-series
#17
Hala Abdullatif, Nabil Mohsen, Rokaya El-Sayed, Fatma El-Mougy, Hanaa El-Karaksy
BACKGROUND AND STUDY AIM: Haemophagocytic lymphohistiocytosis (HLH) is a life-threatening clinical syndrome with liver involvement varying from mild dysfunction to severe fulminant failure. The aim of this study was to present a case series of four HLH patients presenting with acute liver failure (ALF) in the neonatal period. PATIENTS AND METHODS: All four patients were neonates at the onset of symptoms. They presented to Cairo University Pediatric Hospital with ALF; they underwent prompt investigations including determination of ferritin, fibrinogen, and triglyceride levels as part of our ALF workup...
June 2016: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://www.readbyqxmd.com/read/27377227/acute-typhlitis-caused-by-a-caecal-faecolith
#18
Saleh Abdel-Kader, Suhail Al-Salam, Fikri M Abu-Zidan
Isolated acute typhlitis caused by a caecal faecolith is extremely rare. Hereby we report such a case. A 30-year-old man presented clinically as acute appendicitis. During open surgery, an inflamed caecal mass was found. A limited colectomy including the mass and grossly health margins was performed. Histopathological examination confirmed that acute typhlitis was caused by an impacted caecal faecolith. The appendix was normal. Faecolith is an extremely rare cause of acute inflammation of the caecum presenting as a mass which is usually treated by limited right hemicolectomy...
June 2016: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://www.readbyqxmd.com/read/27353055/fibroscan-apri-fib4-and-guci-role-in-prediction-of-fibrosis-and-response-to-therapy-in-egyptian-patients-with-hcv-infection
#19
Ayman Yosry, Rabab Fouad, Shereen A Alem, Aisha Elsharkawy, Mohammad El-Sayed, Noha Asem, Ehsan Hassan, Ahmed Ismail, Gamal Esmat
BACKGROUND AND STUDY AIMS: Multiple noninvasive methods have been used successfully in the prediction of fibrosis. However, their role in the prediction of response to hepatitis C virus (HCV) antiviral therapy is debatable. The aim of this study was to validate and compare the diagnostic performance of FibroScan, APRI (aspartate aminotransferase (AST)-to-platelet ratio index), FIB4, and GUCI (Göteborg University Cirrhosis Index) for the prediction of hepatic fibrosis and treatment outcome in HCV-infected patients receiving pegylated interferon and ribavirin (PEG-IFN/ribavirin)...
June 2016: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://www.readbyqxmd.com/read/27349575/the-prevalence-of-coeliac-disease-in-patients-fulfilling-rome-iii-criteria-for-irritable-bowel-syndrome
#20
Sayed A Shalaby, Moataz M Sayed, Wesam A Ibrahim, Sara M Abdelhakam, Marwa Rushdy
BACKGROUND AND STUDY AIM: The clinical presentation of coeliac disease can vary from a classical malabsorption syndrome to more subtle atypical gastrointestinal manifestations similar to irritable bowel syndrome (IBS). The aim of this study was to investigate the prevalence of coeliac disease in Egyptian patients with clinically diagnosed diarrhoea-predominant IBS (according to Rome III criteria). PATIENTS AND METHODS: This study was conducted on 100 patients with clinically diagnosed diarrhoea-predominant IBS (fulfilling Rome III criteria)...
June 2016: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
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