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Current Opinion in Supportive and Palliative Care

journal
https://www.readbyqxmd.com/read/29697417/chinese-herbal-medicines-in-the-prevention-and-treatment-of-chemotherapy-induced-nausea-and-vomiting
#1
Chang Lv, Chengjin Shi, Lifen Li, Xuesen Wen, Cory J Xian
PURPOSE OF REVIEW: Chemotherapy-induced nausea and vomiting (CINV) critically impact on cancer patients' quality of life, causing various complications, and increasing the risk of chemotherapeutic failure. Current treatments addressing CINV are reasonably costly and have many side effects. Chinese herbal medicines (CHMs) have been widely used in treating CINV in China. Clinical trials and modern experimental studies on CINV using CHMs are reviewed for clues that may help us to better prevent and treat CINV with CHMs, and develop safe and effective treatments...
April 24, 2018: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/29608466/editorial-for-pain-cancer-in-2018
#2
Anthony H Dickenson, Paul Farquhar-Smith
No abstract text is available yet for this article.
March 31, 2018: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/29608465/editorial-for-pain-nonmalignant-diseases-in-2018
#3
Anthony H Dickenson, Kirsty Bannister
No abstract text is available yet for this article.
March 31, 2018: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/29570496/taste-alterations-and-cancer-treatment
#4
Sophie van Oort, Ellen Kramer, Jan-Willem Groot de, Otto Visser
PURPOSE OF REVIEW: In this review, we explore issues on the physiology of taste and smell and we critically review recent literature of taste and smell changes and the impact on food preferences throughout the cancer treatment trajectory. RECENT FINDINGS: Subjective measurements such as validated questionnaires can be valuable for the clinical setting and many studies describe taste and smell changes by self-report. Because both smell and taste are interrelated, these subjective results are difficult to interpret...
March 22, 2018: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/29553988/a-role-for-pericytes-in-chronic-pain
#5
Alexandra M Durrant, Matthew N Swift, Nicholas Beazley-Long
PURPOSE OF REVIEW: The importance of the blood-brain barrier (BBB) and neuroinflammation in neurodegenerative conditions is becoming increasingly apparent, yet very little is known about these neurovascular functions in nonmalignant disease chronic pain. Neural tissue pericytes play critical roles in the formation and maintenance of the BBB. Herein, we review the important roles of neural pericytes and address their potential role in chronic pain. RECENT FINDINGS: Pericytes are implicated in the function of neural microvasculature, including BBB permeability, neuroimmune factor secretion and leukocyte transmigration...
March 16, 2018: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/29553987/chronic-postsurgical-pain-and-cancer-the-catch-of-surviving-the-unsurvivable
#6
Stephen R Humble, Nicolas Varela, Asantha Jayaweera, Arun Bhaskar
PURPOSE OF REVIEW: Chronic postsurgical pain (CPSP) is an important and well recognized cause of much long-term suffering, which in some cases may be preventable and affects many people living with cancer. Unfortunately, general consensus is lacking as to how best reduce the risk of developing CPSP. RECENT FINDINGS: Cancer is now not always a short-lived, fatal disease and is now moving towards a chronic illness. Poorly managed perioperative pain is the greatest risk factor for CPSP...
March 16, 2018: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/29547492/predicting-mucositis-risk-associated-with-cytotoxic-cancer-treatment-regimens-rationale-complexity-and-challenges
#7
Petra Bachour, Stephen T Sonis
PURPOSE OF REVIEW: The goals of this review are to describe the complexity of factors influencing the risk of cancer regimen-related mucosal injury (CRRMI), to evaluate the contribution of the innate immune response to CRRMI risk, to compare the concordance of genome analytics in describing mechanism and risk, and to determine if common biological pathways are noted when CRRMI is compared to a disease with a similar phenotype. RECENT FINDINGS: The pathogenesis of and risk for CRRMI are complex and influenced by multiple intrinsic and extrinsic factors...
March 14, 2018: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/29547491/prophylactic-probiotics-for-cancer-therapy-induced-diarrhoea-a-meta-analysis
#8
Hannah R Wardill, Ysabella Z A Van Sebille, Matthew A Ciorba, Joanne M Bowen
PURPOSE OF REVIEW: Strong preclinical data support prophylactic probiotics as an effective preventive strategy for diarrhoea secondary to anticancer therapies. To determine the composite evidence that this approach translates to the clinic, we performed a meta-analysis of randomized controlled trials (RCTs) of prophylactic probiotics for the prevention of cancer therapy induced diarrhoea. RECENT FINDINGS: A three-step search strategy was used to identify relevant studies (1 June 2000-1 June 2017) investigating probiotic intervention for diarrhoea secondary to any cancer therapy (cytotoxic, targeted and immunotherapies)...
March 14, 2018: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/29608464/how-to-feed-patients-with-gastrointestinal-mucositis
#9
Jann Arends
PURPOSE OF REVIEW: Gastrointestinal mucositis is a frequent side effect of systemic anticancer treatment and radiotherapy. The occurrence endangers body resources by decreasing food intake and absorption. This review highlights new developments in treatment and prevention. RECENT FINDINGS: Recent clinical practice guidelines recommend supplying adequate amounts of energy and nutrients to cancer patients undergoing anticancer treatments. This requires repeated screening for risk of malnutrition and in at-risk patients, assessment of food intake and nutritional status, followed by nutritional interventions targeted at individual deficiencies and tolerance to oral, enteral or parenteral feeding...
June 2018: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/29521658/trophic-factors-in-the-treatment-and-prevention-of-alimentary-tract-mucositis
#10
Mathias Rathe, Rene L Shen, Per T Sangild
PURPOSE OF REVIEW: Mucositis is a common adverse effect of cytotoxic anticancer treatment with serious implications for the quality of life, morbidity and mortality of cancers patients. Although, evidence supporting the use of certain treatments exists there is no gold standard for preventing or treating mucositis. Current management strategies are scarce with recommendations referring primarily to specific cytotoxic treatment regimens in certain clinical scenarios. RECENT FINDINGS: Trophic factors may contribute to preserve epithelial integrity, function, and accelerate regeneration after chemotherapeutic treatment...
June 2018: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/29465470/opioid-addiction-diversion-and-abuse-in-chronic-and-cancer-pain
#11
Vijay Kata, Matthew B Novitch, Mark R Jones, Best O Anyama, Erik M Helander, Alan D Kaye
PURPOSE OF REVIEW: The primary cause of overdose death in the United States is related to pharmaceutical opioids. A few particular populations that struggle with adverse outcomes related to opioid abuse are those in palliative care, those with chronic pain, and those receiving pain treatments secondary to cancer or chemotherapy. RECENT FINDINGS: There have been massive efforts to decrease the use of opioid abuse in patient care in a gestalt manner, but palliative care provides unique challenges in applying these reduction tactics used by other specialties...
June 2018: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/29465469/a-critical-appraisal-of-gabapentinoids-for-pain-in-cancer-patients
#12
Roberta I Jordan, Matthew R Mulvey, Michael I Bennett
PURPOSE OF REVIEW: Gabapentinoids are frequently used in the management of cancer pain. In recent Cochrane systematic reviews, although there was an abundance of evidence relating to non-cancer pain, only a few studies related to cancer pain. This review summarizes recent randomised controlled trials (RCTs) evaluating the use of gabapentinoids for tumour-related (as monotherapy or part of combination therapy) and treatment-related pain. RECENT FINDINGS: For tumour-related pain, ten out of thirteen studies showed statistically significant benefits in favour of gabapentinoids...
June 2018: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/29438129/central-and-peripheral-processes-in-headache
#13
Adithya Varma, Saurabh Jain, Arshad Majid, Milena De Felice
PURPOSE OF REVIEW: Migraine is an extremely incapacitating collection of neurological symptoms that usually includes a severe, throbbing, recurring pain on one side of the head. The World Health Organization ranks migraine as the third most prevalent disease and the seventh commonest primary pain condition in the world. Trigeminovascular-mediated central sensitization has been implicated in the development of migraine symptoms including pain following light touch. This review explores the activation and sensitization of the brain systems that have emerged from recent studies and that contribute to migraine...
June 2018: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/29438128/toxins-in-pain
#14
Fernanda C Cardoso, Mahadhi Hasan, Tianjiao Zhao, Richard J Lewis
PURPOSE OF REVIEW: Pain is a distressing protective sensory experience warning of actual or potential tissue damage. Natural toxins have evolved to exploit pain and related neuronal pathways to facilitate prey capture and for defence, often producing either numbness, paralysis or intense pain by selectively modulating ion channels and receptors in pain pathways. Understanding how toxins modulate pain pathways can enhance our understanding of the physiological and pathological basis of pain...
June 2018: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/29438127/osteoarthritis-pain-recent-advances-and-controversies
#15
Hans-Georg Schaible
PURPOSE OF REVIEW: Osteoarthritis is one of the most frequent causes of chronic pain. Because there is no causal treatment of osteoarthritis, sufficient pain control is of uppermost importance but often not met. The review reports recent advances and controversies in our understanding of osteoarthritis pain and its treatment. RECENT FINDINGS: Osteoarthritis pain is determined by processes at different levels. An important local factor of pain generation in the joint is inflammation such as synovitis, and neuropathic components of osteoarthritis pain are being discussed...
June 2018: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/29432225/nonsteroidal-anti-inflammatory-drugs-and-cancer-pain
#16
Jenny Strawson
PURPOSE OF REVIEW: This review aims to appraise the most recent evidence for the use of NSAIDS in cancer pain. RECENT FINDINGS: The Cochrane review reveals the paucity of high-quality evidence for the use of NSAIDS for cancer pain, highlighting methodological considerations for future research. There is limited evidence for the role of combined NSAIDs (celecoxib and diclofenac) alongside opioids for cancer pain. Recent retrospective data suggests NSAIDS may contribute to better pain control in hospitalized patients...
June 2018: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/29324581/the-silent-struggles-of-survivorship-in-cancer
#17
Janet Ellis, Elie Isenberg-Grzeda
No abstract text is available yet for this article.
March 2018: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/29315091/supported-self-management-for-cancer-survivors-to-address-long-term-biopsychosocial-consequences-of-cancer-and-treatment-to-optimize-living-well
#18
Doris D Howell
PURPOSE OF REVIEW: As individuals are living longer with cancer as a chronic disease, they face new health challenges that require the application of self-management behaviors and skills that may not be in their usual repertoire of self-regulatory health behaviors. Increasing attention is focused on supported self-management (SSM) programs to enable survivors in managing the long-term biopsychosocial consequences and health challenges of survivorship. This review explores current directions and evidence for SSM programs that enable survivors to manage these consequences and optimize health...
March 2018: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/29303840/palliative-care-during-and-following-allogeneic-hematopoietic-stem-cell-transplantation
#19
Sandra A Mitchell
PURPOSE OF REVIEW: The purpose of this review is to synthesize recent literature regarding the provision of palliative care to patients during and following allogeneic hematopoietic stem cell transplantation (HSCT), highlighting factors which mediate impairments in health-related quality of life in this patient population, and the intervention approaches and models of care delivery that clinicians can consider to address unmet needs for palliative care and to strengthen patient and family resiliency...
March 2018: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/29278554/matters-of-the-heart-failing-better
#20
James M Beattie
No abstract text is available yet for this article.
March 2018: Current Opinion in Supportive and Palliative Care
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