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Current Opinion in Supportive and Palliative Care

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https://www.readbyqxmd.com/read/27898512/cancer-related-cognitive-impairment-and-patients-ability-to-work-a-current-perspective
#1
Saskia F A Duijts, Allard J van der Beek, Ingrid G Boelhouwer, Sanne B Schagen
PURPOSE OF REVIEW: About half of all cancer survivors are 65 years of age or younger and potentially part of the labor force. Increasing numbers of these survivors are able to return to work (RTW) or even continue working during treatment. Many factors are known to inhibit occupational reintegration of cancer survivors, and further affect job performance after RTW. However, the impact of cancer-related cognitive impairment on work-related outcomes in cancer survivors is not well understood...
November 24, 2016: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/27898511/cognitive-behavioral-therapy-for-cancer-related-cognitive-dysfunction
#2
Shelly Kucherer, Robert J Ferguson
PURPOSE OF REVIEW: To provide the reader with an overview of the cognitive-behavioral conceptualization of cancer-related cognitive dysfunction (CRCD) and how cognitive behavioral therapy (CBT) can play an important role in treatment. RECENT FINDINGS: Recent findings show that Memory and Attention Adaptation Training (MAAT), a CBT developed to help cancer survivors develop adaptive skills to improve daily cognitive performance and emotional coping, may be an efficacious treatment of CRCD and can be delivered through videoconference technology to improve survivor access to care...
November 24, 2016: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/27755140/targeting-the-host-immune-system-pd-1-and-pd-l1-antibodies-and-breast-cancer
#3
Shaheenah Dawood, Hope S Rugo
PURPOSE OF REVIEW: This article describes the role of the PD-1 axis and reviews current data and future directions inhibiting PD-1 and PD-L1 in breast cancer. RECENT FINDINGS: Four phase I monotherapy expansion trials in patients with metastatic breast cancer have demonstrated low but durable single agent responses to PD-1 and PD-L1 inhibitors, ranging from 4.8 to 19%. Higher response rates are seen in triple negative breast cancer, compared with hormone receptor positive disease...
October 15, 2016: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/27750261/does-nutrition-support-have-a-role-in-managing-cancer-cachexia
#4
Alessandro Laviano, Gianluca Di Lazzaro Giraldi, Angela Koverech
PURPOSE OF REVIEW: Cachexia is a negative prognostic factor in cancer patients. The pathogenesis is related to a variable combination of reduced food intake and metabolic changes. However, whether nutritional support may contribute to effectively prevent and treat cachexia remains a debated issue. RECENT FINDINGS: Consistent evidence demonstrates that anabolic windows of opportunity occur during the clinical trajectory of cancer patients. Also, the use of specific nutrients, namely omega-3 fatty acids, may enhance the efficacy of nutritional support when tumor-driven inflammatory response is high...
October 7, 2016: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/27635766/the-impact-of-early-palliative-care-on-the-quality-of-care-during-the-last-days-of-life-what-does-the-evidence-say
#5
Sofia C Zambrano, Monica C Fliedner, Steffen Eychmüller
PURPOSE OF REVIEW: The aim of this review is to critically appraise the existing evidence on 'early palliative care' (EPC), discuss its relationship with advance care planning, and to reflect on the impact of EPC on the quality of care provided during the last days of life. RECENT FINDINGS: There are indicators that EPC may help to avoid aggressive treatment, shorten hospital stay, improve overall quality of life, and to see more frequently dying and death at the preferred place of care...
September 15, 2016: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/27635764/caregivers-burden-in-palliative-care-patients-a-problem-to-tackle
#6
Verónica Inés Veloso, Vilma Adriana Tripodoro
PURPOSE OF REVIEW: To revise the family caregiver's burden concept and to understand the implications for the patient, family and healthcare system. We analyzed recent literature in three main areas: the role of family caregiver at the end of life, the family caregiver's burden and the involvement of social care networks. RECENT FINDINGS: The family caregiver often accepts the caring as a natural action, presumably imposed by the society. A recent review described seven main roles of care which, according to family system and society, consist of different tasks and activities...
September 15, 2016: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/27782974/editorial-introductions
#7
(no author information available yet)
No abstract text is available yet for this article.
December 2016: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/27684531/does-physical-exercise-improve-quality-of-life-of-advanced-cancer-patients
#8
Alfredo Navigante, Pablo Cresta Morgado
PURPOSE OF REVIEW: We discuss the principal issues about physical activity in advanced cancer patients through the analyses of the last articles and our experience in this field. RECENT FINDINGS: The efficacy of exercise training intervention could improve quality of life (QOL), fatigue and well being in advanced cancer patients. Several published studies have included, nevertheless, patients with early stage of disease and more recently, populations of patients with local advanced tumors of the breast, rectum and lung, who are undergoing neoadjuvant therapy...
December 2016: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/27661210/neuroleptics-in-the-management-of-delirium-in-patients-with-advanced-cancer
#9
David Hui, Rony Dev, Eduardo Bruera
PURPOSE OF REVIEW: Delirium is the most common and distressing neuropsychiatric syndrome in cancer patients. Few evidence-based treatment options are available due to the paucity of high quality of studies. In this review, we shall examine the literature on the use of neuroleptics to treat delirium in patients with advanced cancer. Specifically, we will discuss the randomized controlled trials that examined neuroleptics in the front line setting, and studies that explore second-line options for patients with persistent agitation...
December 2016: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/27635765/practical-multimodal-care-for-cancer-cachexia
#10
Matthew Maddocks, Jane Hopkinson, John Conibear, Annie Reeves, Clare Shaw, Ken C H Fearon
PURPOSE OF REVIEW: Cancer cachexia is common and reduces function, treatment tolerability and quality of life. Given its multifaceted pathophysiology a multimodal approach to cachexia management is advocated for, but can be difficult to realise in practice. We use a case-based approach to highlight practical approaches to the multimodal management of cachexia for patients across the cancer trajectory. RECENT FINDINGS: Four cases with lung cancer spanning surgical resection, radical chemoradiotherapy, palliative chemotherapy and no anticancer treatment are presented...
December 2016: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/27607756/promoting-patient-centred-palliative-care-a-scoping-review-of-the-patient-dignity-question
#11
María Arantzamendi, Alazne Belar, Marina Martínez
PURPOSE OF REVIEW: In recent years, there has been a growing interest in promoting dignity in care, and specific interventions have been developed to include it at the end of life. The patient dignity question (PDQ) is a recent, novel and simple intervention that healthcare professionals can implement; however, little information is known about its impact. This scoping review aims to examine and map out the PDQ literature. RECENT FINDINGS: Studies suggest that patients, families and professionals have a positive view of the PDQ in that it helps to get to know patients and provide them with the best care possible...
December 2016: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/27490147/inspiring-change-humanities-and-social-science-insights-into-the-experience-and-management-of-breathlessness
#12
Rebecca Oxley, Jane Macnaughton
PURPOSE OF REVIEW: Breathlessness can be debilitating for those with chronic conditions, requiring continual management. Yet, the meaning of breathlessness for those who live with it is poorly understood in respect of its subjective, cultural, and experiential significance. This article discusses a number of current issues in understanding the experience of breathlessness. RECENT FINDINGS: Effective communication concerning the experience of breathlessness is crucial for diagnosis, to identify appropriate treatment, and to provide patients with the capacity to self-manage their condition...
September 2016: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/27489184/editorial-introductions
#13
(no author information available yet)
No abstract text is available yet for this article.
September 2016: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/27489183/the-evolving-role-of-chemotherapy-in-prostate-cancer
#14
Fred Saad
No abstract text is available yet for this article.
September 2016: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/27489182/what-can-we-learn-about-breathlessness-from-population-based-and-administrative-health-data
#15
Magnus Ekström
PURPOSE OF REVIEW: To review the findings and methodological strengths and limitations of studies of breathlessness using population-based or routinely collected data, including the novel methodology of the registry-based randomized controlled trial (R-RCT). RECENT FINDINGS: Breathlessness severe enough to restrict activity is common and increases in the last months of life both among elderly in the community and among patients in specialized palliative care. During the last week of life, risk factors for more severe breathlessness have been identified...
September 2016: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/27387765/whose-value-is-it-anyway-clinical-ethics-in-palliative-and-supportive-care
#16
Irene Ying, Sally Bean
No abstract text is available yet for this article.
September 2016: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/27387764/breathlessness-and-inflammation-potential-relationships-and-implications
#17
Richella Ryan, Anna Spathis, Angela Clow, Sara Booth
PURPOSE OF REVIEW: Breathlessness and chronic inflammation both span a wide range of disease contexts and hold prognostic significance. The possibility of a causal relationship between the two has been hypothesized. The aims of this article are to review the intersections between breathlessness and inflammation in the literature, describe potential mechanisms connecting the two phenomena, and discuss the potential clinical implications of a causal relationship. RECENT FINDINGS: There is a very limited literature exploring the relationship between systemic inflammation and breathlessness in chronic obstructive pulmonary disease, heart failure, and cancer...
September 2016: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/27380222/physiological-and-functional-failure-in-chronic-obstructive-pulmonary-disease-congestive-heart-failure-and-cancer-a-debilitating-intersection-of-sarcopenia-cachexia-and-breathlessness
#18
Deborah Dudgeon, Vickie E Baracos
PURPOSE OF REVIEW: Loss of skeletal muscle mass and cachexia are important manifestations of chronic obstructive pulmonary disease and have been associated with breathlessness, functional limitation and poor prognosis. A number of other life-limiting illnesses, including cancer and chronic heart failure as well as acute conditions seen in ICU such as sepsis, are characteristically associated with cachexia and sarcopenia. These conditions may have respiratory muscle atrophy of sufficient magnitude to contribute to the development of breathlessness and associated functional limitation...
September 2016: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/27380221/service-delivery-of-complex-interventions-for-refractory-breathlessness
#19
Sara Booth, Richella Ryan, Anna Spathis
PURPOSE OF REVIEW: The review considers the evidence for different service models existing for helping people manage the chronic, irreversible breathlessness that accompanies advanced disease. RECENT FINDINGS: Many of the service models that are delivering care have not yet published their results in the scientific literature because these ideas, and the methods to evaluate them, are relatively new. There are three randomized controlled trials published which demonstrate the effectiveness of this approach and one which suggests that more episodes of some intervention components are not necessarily better...
September 2016: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/27380220/a-systematic-literature-review-on-the-ethics-of-palliative-sedation-an-update-2016
#20
Blair Henry
PURPOSE OF REVIEW: Palliative sedation has been the subject of intensive debate since its first appearance in 1990. In a 2010 review of palliative sedation, the following areas were identified as lacking in consensus: inconsistent terminology, its use in nonphysical suffering, the ongoing experience of distress, and concern that the practice of palliative sedation may hasten death. This review looks at the literature over the past 6 years and provides an update on these outstanding concerns...
September 2016: Current Opinion in Supportive and Palliative Care
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