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B Papaziogas, S Kapoulas, E Christoforidis
No abstract text is available yet for this article.
July 2016: Hippokratia
Undefined DemiropoulosF, K Papazoglou, D Miliaras
No abstract text is available yet for this article.
July 2016: Hippokratia
M Gogou, A Keivanidou, A Giannopoulos
No abstract text is available yet for this article.
July 2016: Hippokratia
D Krasic, M Trajkovic, N Zivkovic
No abstract text is available yet for this article.
July 2016: Hippokratia
M Koutouzis, A Ziakas, M Didagelos, C Maniotis, Z Kyriakides
BACKGROUND: Switching to femoral after a failed radial approach carries an increased risk of bleeding complications since the femoral artery puncture is performed in patients already anticoagulated. Moreover, dedicated radial operators find it more and more difficult to use the femoral approach, and ulnar artery cannulation provides them with the opportunity to further reduce its use. Our objective was to evaluate the feasibility and safety of ipsilateral radial and ulnar artery cannulation during the same coronary catheterization procedure...
July 2016: Hippokratia
P Mavroidis, V Roka, S Kostopoulos, G Batsikas, E Lavdas
BACKGROUND: This study aims at demonstrating the ability of BLADE sequences to reduce or even eliminate all the image artifacts as well as verifying the significance of using this technique in certain pathological conditions. MATERIAL AND METHODS: This study involved fourteen consecutive patients (5 females, 9 males), who routinely underwent magnetic resonance imaging (MRI) brain examination, between 2010-2014. The applied routine protocol for brain MRI examination included the following sequences: i) T2-weighted (W) fluid-attenuated inversion recovery (FLAIR) axial; ii) T2-W turbo spin echo (TSE) axial; iii) T2*-W axial, iv) T1-W TSE sagittal; v) Diffusion-weighted (DWI) axial; vi) T1-W TSE axial; vii) T1-W TSE axial+contrast...
July 2016: Hippokratia
G Mihaylov, V Varbanova, V Stoeva, T Dikov
BACKGROUND: Chronic myelogenous leukemia (CML) is a hematological malignancy that originates in an abnormal pluripotent bone marrow stem cell. CML is consistently associated with the expression of the BCR-ABL1 fusion gene, generated by the t(9;22) chromosomal translocation, thus creating the Philadelphia chromosome, a target for protein tyrosine kinase inhibitor (TKI) therapy.  There is no published data, demonstrating increased risk for development of second cancers, associated with the exposure to TKIs...
July 2016: Hippokratia
P Rouskas, G Giannakoulas, A Kallifatidis, H Karvounis
BACKGROUND: Parachute mitral valve (PMV) is commonly associated with mitral valve stenosis but may occasionally be associated with mitral valve regurgitation. CASE REPORT: We present a case of an asymptomatic 41-year-old female with a background of incomplete Shone's complex displaying a PMV regurgitation pattern. CONCLUSION: Cardiovascular imaging with the use of transoesophageal echocardiogram and cardiac magnetic resonance were essential tools for the diagnosis and quantification of the severity of mitral valve regurgitation...
July 2016: Hippokratia
V Kamperidis, E Michou, K Kouskouras, O Nikolaidou, H Karvounis
BACKGROUND: Contrast-enhanced transesophageal echocardiography (TEE) for the opacification of left atrial appendage (LAA) is not clearly suggested by the current guidelines and only scarce data are available. CASE PRESENTATION: A patient with a membrane-like structure in the LAA cavity is presented. Contrast-enhanced TEE revealed LAA pericardial effusion and this diagnosis was confirmed by cardiac magnetic resonance that offered comparable images and tissue characterization...
July 2016: Hippokratia
D Aleksic, S Miletic-Drakulic, T Boskovic-Matic, S Simovic, G Toncev
BACKGROUND: We report the case of a 35-year-old man with stroke related to infective endocarditis (IE) caused by Kocuria kristinae. CASE DESCRIPTION: The patient with chronic hepatitis C virus infection and a former intravenous drug user developed a stroke suddenly, after three months duration of fever and malaise. Duplex ultrasonography of the carotid arteries (zero level diastolic flow, diastolic reversed flow) focused attention to cardiac valve pathology and endocarditis (definite confirmation was made by transesophageal echocardiography)...
July 2016: Hippokratia
A Tragiannidis, E Vasileiou, M Papageorgiou, L Damianidou, E Hatzipantelis, N Gombakis, A Giannopoulos
BACKGROUND: Bone involvement represents a common symptom at diagnosis in children with acute lymphoblastic leukemia, and its prognostic value is not entirely clarified. The aim of this study was to evaluate bone involvement at diagnosis in children with acute lymphoblastic leukemia as a predictive factor and to correlate its presence with other demographic, clinical, and laboratory findings. METHODS: We retrospectively reviewed the medical records of 97 children with acute lymphoblastic leukemia diagnosed from January 2005 to December 2014...
July 2016: Hippokratia
A N Tzavellas, E Kenanidis, M Potoupnis, S Pellios, E Tsiridis, F Sayegh
BACKGROUND: Prognostic value of Salter-Harris (SH) classification is well established. Its reliability, however, can be questioned. We aim to evaluate the interobserver and intraobserver reliability of SH classification and to correlate the level of rater's experience with the correct scoring for each SH subclass. METHODS: Twenty-eight independent raters stratified in three levels of seniority evaluated 50 randomly selected radiographs of physeal injuries. The interval for intraobserver reliability was 12 weeks...
July 2016: Hippokratia
G Vourli, G Papatheodoridis, M Raptopoulou, G N Dalekos, A Hounta, G Nikolopoulou, I Zouboulis-Vafeiadis, E Manesis, G Kitis, C Gogos, I Ketikoglou, G Hatzis, T Vasilialdis, S Karatapanis, K Mimidis, C Drakoulis, G Touloumi, The Hepnet-Greece
BACKGROUND AND AIMS: Although effective treatment in terms of inducing virological and biochemical response for chronic hepatitis B (CHB) is available, its effect on the clinical course of the disease has not yet been accurately estimated. Objective of this study was to evaluate the effect of antiviral therapy and its type [interferon +/- nucleos(t)ide analogs (NAs) vs. NAs] on the occurrence of a clinical event (liver decompensation, liver transplant, hepatocellular carcinoma and death from a liver-related cause) in CHB patients...
July 2016: Hippokratia
A Vavlitou, G Minas, S Zannetos, T Kyprianou, M Tsagourias, D Matamis
BACKGROUND: Patent foramen ovale (PFO) is an anatomic variant that may lead to several pathological conditions, notably right to left shunt, paradoxical embolism, hypoxemia, and cerebral fat embolism. Mechanical positive pressure ventilation may increase the prevalence of PFO opening in Intensive Care Unit (ICU) patients; however, the respiratory and hemodynamic determinants of PFO opening have been poorly investigated. Contrast-enhanced transesophageal echocardiogram (ce-TEE) is considered the gold standard for PFO detection...
July 2016: Hippokratia
S Arif, J Wojtasik, A Dziewierz, K Bartuś, D Dudek, S Bartuś
BACKGROUND: Carotid artery stenting (CAS) is an alternative to carotid endarterectomy for the prevention of stroke and transient ischemic attack (TIA). The high long-term mortality among patients who underwent CAS seems to be related to the high comorbidity burden, including coronary and peripheral artery disease. However, limited data on very long-term mortality (over four years) and predictors of death are available. AIM: We sought to investigate the very long-term survival after CAS and the impact of comorbidities on mortality at follow-up...
July 2016: Hippokratia
A Inci, R Olmaz, F Sarı, M Coban, H Y Ellidag, M Sarıkaya
BACKGROUND: In the present study, we aimed to assess the relationship between the levels of soluble Klotho (s-Klotho) and oxidative stress markers in diabetic nephropathy patients with different stages of chronic kidney disease (CKD) and albuminuria levels. METHODS: We enrolled 109 patients with type 2 diabetes (mean age, 61.63 ± 9.77 years) and 32 healthy controls (mean age, 49.53 ± 7.32 years) between January and June 2014.  Patients were classified into three groups based on their urinary albumin/creatinine ratio (UACR)...
July 2016: Hippokratia
G Boulogianni, I Chryssogonidis, A Drevelegas
BACKGROUND: The most common histological types of invasive breast carcinomas are the invasive ductal carcinoma (IDC) and the invasive lobular carcinoma (ILC). The purpose of our study was to evaluate the role of the diffusion-weighted imaging (DWI) and the in vivo proton magnetic resonance spectroscopy ((1)H-MRS ) at 3 Tesla magnet in invasive breast cancer and correlate them with the dynamic contrast enhancement (DCE) and pathologic findings. METHODS: We retrospectively studied at 3Tesla magnet the apparent diffusion coefficient (ADC) values, the detection of choline in the (1)H-MRS and the kinetic analyses obtained after DCE in 181 patients with histologically confirmed invasive breast carcinomas...
July 2016: Hippokratia
B Rovcanin, S Damjanovic, V Zivaljevic, A Diklic, M Jovanovic, I Paunovic
BACKGROUND: Medullary thyroid carcinoma (MTC) is a type of thyroid neoplasm which originates from parafollicular cells, and it is commonly diagnosed by calcitonin screening. Besides the sporadic form, the heritable form of MTC is characterized by constitutive activation of the RET (REarranged during Transfection) proto-oncogene caused by different mutations. METHOD: We collected data regarding RET genetic screening performed in the Center for Endocrine Surgery in Belgrade during a 20-year-period...
July 2016: Hippokratia
A Petrou, P Tzimas, S Siminelakis
BACKGROUND: Severe or massive bleeding in cardiac surgery is an uncommon but important clinical scenario. Its existing definitions are diverse. Its characteristics constantly change during an active hemorrhage and, thus is difficult to define appropriately. METHODS: In this narrative, non-systematic review, we performed a literature search to retrieve data that could contribute to answering clinical questions on the definition and grading of severe hemorrhage and massive transfusion, identifying factors that predict and affect bleeding and transfusion-related mortality and describing the risks of re-exploration and the economic impact of severe bleeding in cardiac surgery...
July 2016: Hippokratia
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