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Acta Bio-medica: Atenei Parmensis

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https://www.readbyqxmd.com/read/29083346/indoors-and-health-results-of-a-systematic-literature-review-assessing-the-potential-health-effects-of-living-in-basements
#1
Angelo Giosué Mezzoiuso, Marco Gola, Andrea Rebecchi, Matteo Riccò, Stefano Capolongo, Maddalena Buffoli, Marcello Tirani, Anna Odone, Carlo Signorelli
A new law approved in March 2017 in the Lombardy Region makes it possible to live in basements. Basements are defined as buildings partly below curb level but with at least one-half of its height above the curb. Basements' features and structural characteristics might pose risks to human health. In this paper we adopt a multidisciplinary approach to assess the potential health effects of living in basements. In particular, we define a conceptual framework to describe basements' structural characteristics which are risk factors, as well as the mechanisms through which they impact on human health...
October 23, 2017: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/29083345/risk-management-the-new-normative-scenario-and-the-role-of-training-and-education
#2
Antonio Ferrari, Anna Odone, Paolo Mandelli, Carlo Signorelli
The article focuses on the important issue of Risk Management in health. In particular, it describes and critically appraises the new Italian law on patients' safety and professional responsibility, and expand on the educational and training needs to implement it on the ground. On the basis of the new law the role of Risk Managers, responsible for quality and safety of healthcare services, becomes of crucial importance in both public and private hospitals in Italy. In such context, education and training of risk managers should be multi disciplinary, ad hoc designed on recent regulations, and, more in general, help to build a new era in healthcare management...
October 23, 2017: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/29083344/invasive-meningococcal-disease-on-the-workplaces-a-systematic-review
#3
Matteo Riccò, Luigi Vezzosi, Anna Odone, Carlo Signorelli
Background and aims of the work: Invasive Meningococcal Disease (IMD) represents a global health threat, and occupational settings have the potential to contribute to its spreading. Therefore, here we present the available evidences on the epidemiology of IMD on the workplaces. METHODS: The following key words were used to explore PubMed: Neisseria meningitidis, meningococcus, meningococcal, invasive meningococcal disease, epidemiology, outbreaks, profession(al), occupation(al). RESULTS: We identified a total of 12 IMD cases among healthcare workers (HCW), 44 involving biological laboratory workers (BLW), 8 among school personnel, and eventually 27 from other settings, including 3 large industrial working populations...
October 23, 2017: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/29083343/forensic-epidemiology-in-italy-principles-and-practice
#4
Valentina Chiesa, Anna Odone, Carlo Signorelli
Forensic epidemiology (FE) implies the use of epidemiological data in the processes and the involvement of epidemiologists in judicial proceedings. FE is essential for the assessment of causal association between the exposure to specific agents and the occurrence of diseases. In this paper we describe FE principles and applications in the Italian context as in recent years FE emerged increasingly as well as the need of experienced and trained epidemiological experts able to navigate legal proceedings. In the literature, the principles of FE have been widely described by different authors, among them: Kennet Rothman who introduced the definition of cause, Sir Austin Bradford Hill who proposed an analytic framework to assess the causal association, and recently by Sana Loue who described the actual legislation and application of FE in the United States...
October 23, 2017: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/29083342/the-pharmaceutical-care-and-the-rejected-constitutional-reform-what-might-have-been-and-what-is
#5
Margherita Siracusa, Iolanda Grappasonni, Fabio Petrelli
This study analyzes the current state of legislation pertaining to pharmaceutical/health care in a period of normative ferment characterized by continuous changes, after countless discussions that have been held on a proposed constitutional reform (rejected by the will of the people at the end of 2016). After a general reflection on the division of legislative powers between the State and its Regions, in the light of attempts to bring about a reform, we will analyse specific problems: from the recent, but in some ways already defined as historic, approval of the new Essential Levels of Care (LEC), the approval of the 2017 Budget Law (concerning important items such as the purchase of drugs), until we reach the Draft Law on competition which is in the process of being approved...
October 23, 2017: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/29083341/a-case-of-refractary-epilepsy-and-related-pain-due-to-dysmenorrhea-solved-with-loading-dose-of-lacosamide-clinical-and-neurophysiological-correlates
#6
Nicolino Marchitto, Umberto Ceratti, Serenella Dalmaso, Gianfranco Raimondi
 In most cases, the etiology of epilepsy is unknown, although some individuals may develop epilepsy as a result of certain brain injuries, following a stroke, a brain tumor or because of drugs and alcohol. Even some rare genetic mutations may be related to the onset of the condition. Seizures are the result of excessive and abnormal activity of neurons in the cerebral cortex. In this case report we show a clinical case of refractory epilepsy due to pain related to uncontrolled dysmenorrhea. The patient, 43 yrs old, had a history of epilepsy of 20 years and ovarian cancer...
October 23, 2017: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/29083340/nab-paclitaxel-after-docetaxel-hypersensitivity-reaction-case-report-and-literature-review
#7
Benedetta Pellegrino, Daniela Boggiani, Chiara Tommasi, Dante Palli, Antonino Musolino
Taxanes, including paclitaxel and docetaxel, are one of the most active cytotoxic agents in breast cancer  treatment  including  Her-2  positive  subtype characterized  by  aggressive  clinical  and pathological features since the early stage. However, their use is sometimes limited by the occurrence of hypersensivity reactions (HSRs) characterized by erythematous rashes, bronchospasm, respiratory distress, hypotension, and pulmonary edema. Cross-reactions between paclitaxel and docetaxel are described in literature with a rate ranging from 49% to 90%...
October 23, 2017: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/29083339/reoperation-for-persistent-or-recurrent-secondary-hyperparathyroidism
#8
Alida Abruzzo, Maria Concetta Gioviale, Giuseppe Damiano, Vincenzo Davide Palumbo, Salvatore Buscemi, Giulia Lo Monte, Leonardo Gulotta, Giuseppe Buscemi, Attilio Ignazio Lo Monte
BACKGROUND: Secondary hyperparathyroidism is a common acquired disorder seen in chronic renal failure. Its pathophysiology is mainly due to hyperphosphatemia and vitamin D deficiency and resistance. When medical treatment fails, subtotal and total parathyroidectomy with autotransplantation are the standard procedures, although both are associated with high recurrence rates. METHODS AND RESULTS: 4 patients experienced persistence and 9 relapse. The first 4 were subjected to reoperation after 6 months for the persistence of symptoms due to the finding of a supernumerary adenomatous gland while the remaining patients at the reoperation showed in 5 cases 2 more glands in over thymic position, and 4 an hyperplasia of the residual glandular tissue...
October 23, 2017: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/29083338/enlarged-virchow-robin-spaces-in-a-young-man-a-constrained-spherical-deconvolution-tractography-study
#9
Alberto Cacciola, Rocco Salvatore Calabrò, Antonio Costa, Antonino Naro, Demetrio Milardi, Daniele Bruschetta
BACKGROUND AND AIM: Virchow-Robin spaces are mainly located along the path of the lenticulo-striate arteries in the basal ganglia through the anterior perforate substance, and can be found both in normal subjects, as a rare phenomenon, and in patients with different diseases. We report a case of a healthy young man with unilateral enlarged Virchow-Robin spaces in the left capsule-lenticulostriate area. Aim of this case report is to show the potential of probabilistic Constrained Spherical Deconvolution (CSD) tractography in showing abnormal diffusion tensor imaging and tractography of the anterior thalamic tracts caused by mass effect from adjacent enlarged Virchow-Robin spaces...
October 23, 2017: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/29083337/ethical-issues-in-paleopathological-and-anthropological-research-experiences
#10
Marta Licata, Francesca Monza
BACKGROUND AND AIM: In recent years, archaeologists and anthropologists involved in the study of human remains have had to take into consideration ethical issues, which have come to the fore. The aim of this study is to illustrate the ethical and religious issues involved in relation to the positions of researchers. METHOD: Ethical issues involve the different study phases of human remains: archaeological excavation, anthropological analysis and, finally, museum display...
October 23, 2017: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/29083336/skin-graft-donor-site-a-procedure-for-a-faster-healing
#11
Roberto Cuomo, Luca Grimaldi, Cesare Brandi, Giuseppe Nisi, Carlo D'Aniello
BACKGROUND: The authors want to evaluate the efficacy of fibrillary tabotamp dressing in skin graft-donor site. A comparison was made with Vaseline gauzes. Tabotamp is an absorbable haemostatic product of Ethicon (Johnson and Johnson) obtained by sterile and oxidized regenerated cellulose (Rayon). It is used for mild to moderate bleeding. MATERIALS AND METHODS: 276 patients were subject to skin graft and divided into two group: Group A and Group B. The donor site of patients in Group A was medicated with fibrillary tabotamp, while the patients of Group B were medicated only with Vaseline gauze...
October 23, 2017: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/29083335/laparoscopic-subtotal-gastrectomy-for-the-treatment-of-advanced-gastric-cancer-a-comparison-with-open-procedure-at-the-beginning-of-the-learning-curve
#12
Federico Marchesi, Giuseppina De Sario, Stefano Cecchini, Francesca Tartamella, Matteo Riccò, Andrea Romboli
BACKGROUND: In the last decades, after some initial concern, laparoscopic subtotal gastrectomy (LSG) is gaining popularity also for the treatment of advanced gastric cancer (AGC). The aim of this study is to compare a single surgeon initial experience on LSG and open subtotal gastrectomy in terms of surgical safety and radicality, postoperative recovery and midterm oncological outcomes. METHODS: a case control study was conducted matching the first 13 LSG for AGC with 13 open procedures performed by the same surgeon...
October 23, 2017: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/29083334/use-of-ultraportable-vacuum-therapy-systems-in-the-treatment-of-venous-leg-ulcer
#13
Roberto Cuomo, Giuseppe Nisi, Luca Grimaldi, Cesare Brandi, Carlo D'Aniello
BACKGROUND: The high incidence of venous leg ulcers and the difficult to give a complete healing involves in an increase of costs for National Health System. Main therapies to obtain a fast healing are compressive bandages, treatment of abnormal venous flow and in-situ-strategies of wound care. Negative pressure therapy does not conventionally used, because these systems not allow the use of compression bandages. Recently the development of ultraportable devices has improved the compliance and the results...
October 23, 2017: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/29083333/comparison-of-robotic-and-laparoscopic-radical-type-b-and-c-hysterectomy-for-cervical-cancer-long-term-outcomes
#14
Antonio Pellegrino, Gianluca Raffaello Damiani, Matteo Loverro, Cecilia Pirovano, Giorgio Fachechi, Silvia Corso, Giuseppe Trojano
STUDY OBJECTIVE: To compare the clinical and oncologic outcomes of Robotic radical hysterectomy (RRH) vs Laparoscopic radical hysterectomy (TLRH) in patients with cervical carcinoma. DESIGN: Long term follow-up in a prospective study between March 2010 to March 2016. SETTING: Oncological referral center, department of gynecology and obstetrics of Alessandro Manzoni Hospital, department of gynecology, University of San Gerardo Monza, Milan...
October 23, 2017: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/29083332/development-of-public-health-program-for-type-1-diabetes-in-a-university-community-preliminary-evaluation-of-behavioural-change-wheel
#15
Ezekiel Uba Nwose, K A Digban, A E Anyasodor, P T Bwititi, R S Richards, E O Igumbor
BACKGROUND: Diabetes mellitus, including type 1 is a global public health problem among the young persons. While public health campaign and screening program is a potential strategy, but communication skills, knowledge and opinion of the healthcare personnel are indicated as variables that can impact patient's education, which will lead to better outcome of care. Thus, in designing or planning a program for public health, workforce development considers opinion and behavioural change wheel of prospective personnel...
October 23, 2017: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/29083331/the-effect-of-remifentanil-on-succinylcholine-induced-changes-in-serum-potassium-and-creatine-kinase-a-prospective-randomized-double-blind-study
#16
Karim Nasseri, Shoaleh Shami, Mousa Shirmohammadi, Farzad Sarshivi, Negin Ghadami
BACKGROUND AND AIM OF THE WORK: Succinylcholine is still included as drugs favored by anesthetists because of its rapid onset and short duration of action. However, it can bring about complications such as hyperkalemia and increased serum creatine phosphokinase (CPK). This study aims at evaluating the effects of remifentanil on succinylcholine-induced postoperative changes in serum potassium and CPK. METHODS: In this study, 59 patients with short term lower abdominal surgery were randomly divided into two groups...
October 23, 2017: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/29083330/peculiarities-of-autoimmune-polyglandular-syndromes-in-children-and-adolescents
#17
Giuseppina Zirilli, Simona Santucci, Chiara Cuzzupè, Domenico Corica, Elda Pitrolo, Giuseppina Salzano
BACKGROUND: no reviews have specifically addressed , to now, whether autoimmune polyglandular syndromes (APSs) may have a peculiar epidemiology and phenotypical expression in pediatric ageObjectives: to review the most recent literature data about the specific epidemiological and clinical peculiarities of APSs in childhood and adolescenceDesign: the main features of the different APSs in pediatric age were compared among them. CONCLUSIONS: 1) Among the different APSs, the one that is most typical of pediatric age is APS-1; 2) APS-1 is not characterized only by the classical triad (chronic moniliasis-hyposurrenalism-hypoparathyroidism) and its clinical spectrum is enlarging over time; 3)APS-2 may have a different epidemiological and clinical expression according to two different nosological classifications...
October 23, 2017: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/29083329/selenium-homeostasis-and-clustering-of-cardiovascular-risk-factors-a-systematic-review
#18
Mojgan Gharipour, Masoumeh Sadeghi, Mehrdad Behmanesh, Mansour Salehi, Pouya Nezafati, Amin Gharpour
  Selenium is a trace element required for a range of cellular functions. It is widely used for the biosynthesis of the unique amino acid selenocysteine [Sec], which is a structural element of selenoproteins. This systematic review focused on the possible relation between selenium and metabolic risk factors. The literature was searched via PubMed, Scopus, ISI Web of Science, and Google Scholar. Searches were not restricted by time or language. Relevant studies were selected in three phases. After an initial quality assessment, two reviewers extracted all the relevant data, whereas the third reviewer checked their extracted data...
October 23, 2017: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/29083328/current-trends-in-etiology-prognosis-and-therapeutic-aspects-of-parkinson-s-disease-a-review
#19
A J Jagadeesan, R Murugesan, S Vimala Devi, M Meera, G Madhumala, M Vishwanathan Padmaja, A Ramesh, A Banerjee, S Sushmitha, A N Khokhlov, F Marotta, Surajit Pathak
Parkinson's disease (PD) is a movement disorder, mainly affecting population consisting of the aged. PD occurs chiefly due to progressive loss of dopaminergic neurons in nigrostriatal pathway. Largely, PD patients suffer from non-motor symptoms, such as depression, anxiety, fatigue, and sleep disorders, that needs further investigation and addressing during PD research. Depression in PD is a predominant and complex symptom, and its pathology exists extrinsic to the nigrostriatal system. This disease can  ultimately be managed by a combination of regular physiotherapy and proper medication...
October 23, 2017: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/29083327/a-new-journal-section-on-health-system-s-research-purpose-and-rationale
#20
Carlo Signorelli, Anna Odone, Nicola Florindo, Massimo Fabi, Maurizio Vanelli
N/A.
October 23, 2017: Acta Bio-medica: Atenei Parmensis
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