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Journal of Nepal Health Research Council

Bigen Man Shakya, Ninadini Shrestha
The postoperative pain management in the elderly is challenging due to comorbidities and change in physiology due to age itself. This limit the use of medication which include pain medication also. The fascia iliaca compartment block has been described in the literature for fracture of femur. It has even been safely used by non anaesthesiologist also. To our knowledge, we did not find any case report of continuous fascia iliaca compartment block published in Nepal. This is our first experience of successful continous fasicia iliaca compartment block in case of 89 year old lady with multiple co morbidities in whom traditional pain medication might be difficult to use...
July 4, 2018: Journal of Nepal Health Research Council
Sudeep Acharya, Sandhya Joshi, Rajib Chaulagain
Fibrodysplasia ossificans progressiva is a genetic disorder of the connective tissue differentiation characterized by congenital malformation of the big toes and progressive heterotopic ossification in the extra skeletal tissues like tendons, ligaments, fascia and skeletal muscles leading to permanent disability. The prevalence is one in two million people. During childhood, it may be asymptomatic but in later life, progressive stiffness of major joints renders movement of the individual impossible. Currently, there is no effective treatment for this debilitating disease...
July 4, 2018: Journal of Nepal Health Research Council
Tanka Prasad Bohara, Uttam Laudari, Anuj Parajuli, Shail Rupakheti, Mukund Raj Joshi
BACKGROUND: Early identification of severe acute pancreatitis is important for early stratification, goal directed fluid therapy, rationalizing level of care to improve outcome. Various clinical, laboratory and imaging scoring system has been used to identify severe acute pancreatitis with variable results. Recently a decision tree model was proposed using serum creatinine, serum lactate dehydrogenase and oxygenation index to predict severe acute pancreatitis. This system is easy and usable at our centre...
July 4, 2018: Journal of Nepal Health Research Council
Amit Mani Upadhyay, Ashok Kunwar, Sanjesh Shrestha, Hema Kumari Pradhan, Aruna Karki, Ganesh Dangal
BACKGROUND: Iatrogenic ureteric injuries leading to fistula are rare but devastating complications of obstetric and gynecological surgeries. The aim of the study was to review the demography of ureterovaginal fistula (UVF) and its surgical outcome in Kathmandu Model Hospital. METHODS: This is a review of 15 patients of ureterovaginal fistula who were referred to department of Obstetrics and Gynaecology of Kathmandu Model Hospital from Feb 2014 to Sept 2017. We reviewed the demography, causes and surgical outcome of ureterovaginal fistula (UVF)...
July 4, 2018: Journal of Nepal Health Research Council
Rajesh Dhoj Joshi, Sachin Khadka, Deepak Man Joshi, Basudha Shrestha, Ganesh Dangal, Kiran Prasad Acharya, Sanjit Shrestha, Yashad Dongol
BACKGROUND: For diagnosis of enteric fever, the culture of the organism from different body fluids is the gold standard. After diagnosis, it is important to treat with the right antibiotic before any complications can occur. The retrospective study is designed to explore the antibiotic sensitivity trend in blood culture positive typhoid fever cases and the extent of drug resistance before treatment is administered. METHODS: A retrospective study was carried out for culture isolated enteric fever patients admitted in Kathmandu Model Hospital...
July 3, 2018: Journal of Nepal Health Research Council
Smriti Shrestha
BACKGROUND: Acne beyond 25 years of age is frequently associated with hormonal derangement in women. Hormonal association provides the impetus for hormonal therapy as well as underpins the need for blood investigations in this population. Hence, we aim to estimate the presence of hormonal derangement and lipid alteration in female adult acne. METHODS: A prospective, observational study was conducted in Dhulikhel Hospital from July 2015 to February 2016. Females older than 25 years with acne were taken in the study after informed consent...
July 3, 2018: Journal of Nepal Health Research Council
Niki Shrestha, Sanjeeb Shah, Gayatri Khanal, Suneel Piryani
BACKGROUND: Health professional students play a critical role in tobacco control by providing services, advocating for policies and serving as role models for social change. This study aimed to estimate the prevalence of tobacco use and determine the attitude and behavior regarding tobacco use among health professional students. METHODS: A cross-sectional study was conducted among third-year medical, dental, nursing and pharmacy undergraduates using GHPSS questionnaire...
July 3, 2018: Journal of Nepal Health Research Council
Anshumala Joshi, Meeta Thapa, Om Biju Panta
BACKGROUND: Whether a mother should be allowed to choose between the modes of delivery is a matter of concern among practicing obstetricians. This study aims to explore the knowledge of the Nepalese women attending a tertiary care center about the benefits and complications of vaginal and caesarean delivery and their attitude and preference for the method of delivery. METHODS: The study was a hospital based cross sectional questionnaire survey conducted in Nepal Medical College teaching Hospital, Jorpati from 1stShrawan 2074 to 31st Ashoj 2074...
July 3, 2018: Journal of Nepal Health Research Council
Madhusudan Saha, Dipal Krishna Adhikary, Irin Parvin, Yuba Raj Sharma, Fahmida Akhter, Monojit Majumder
BACKGROUND: Childhood obesity is found in affluent society, less physical activity and changes in food pattern. This study was designed to see prevalence and risk factors of childhood obesity among school children of Sylhet city. METHODS: Students of class five and six of two schools of Sylhet city were randomly selected. Demographic and anthropometric data were collected and recorded in predesigned data sheet. BMI and percentile were calculated using official centre for disease control growth chart for 2 to 20 years...
July 3, 2018: Journal of Nepal Health Research Council
Krishna Kumar Aryal, Astrid Alvik, Narbada Thapa, Suresh Mehata, Tara Roka, Pushpa Thapa, Pragya Pandey, Babill Stray Pedersen
BACKGROUND: Common mental disorders such as anxiety and depression among mothers of young children and expectants can silently deteriorate the health of the mother with significant impact on the newborn. The primary aims were to determine the proportion of pregnant women and mothers of children under one year with anxiety and depression and their associated factors in Sindhupalchowk. METHODS: We used the Hopkins Symptom Checklist 25 and a structured questionnaire in a cross-sectional study to collect information from 778 women (164 pregnant women, 614 mothers of children under one year) selected through multi-stage sampling...
July 3, 2018: Journal of Nepal Health Research Council
Shanta Sharma, Indra Dhakal
BACKGROUND: Child birth is a universally celebrated occasion, yet everyday for thousands of women child birth is experienced not as a joyful event as it should be, but as a private hell that may even end in death. The objective of this study is to determine the complications of normal delivery and cesarean section on the mothers and new born. METHODS: A descriptive study was conducted in two selected hospitals of Rupandehi district, Nepal. Data was collected as per pretested structured proforma from 550 respondents who were the mothers and new born delivered normally and through cesarean section randomly till the completion of sample size and analyzed by using SPSS, MANOVA and Chi-square test to determine associations between categorical variables...
July 3, 2018: Journal of Nepal Health Research Council
Shrijana Pandey, Chandrakala Sharma
BACKGROUND: Autism Spectrum Disorder is a lifelong developmental disorder that affects children and results in deficit in social interaction, communication and display of unusual pattern of behavior. Though caregiving is a normal parental duty, providing intensive care to a child with long-term problem is burdensome and impacts both physical and mental health of caregivers. The aim of this study was to obtain a picture of burden among caregivers raising children with Autism Spectrum Disorder...
July 3, 2018: Journal of Nepal Health Research Council
Dhiraj Shrestha, Pratigya Thapa, Dinesh Bhandari, Hiramani Parajuli, Prakash Chaudhary, Kabi Thapa, Vijay Kumar Sharma, Pradip Kumar Shah
BACKGROUND: The study was designed to provide account of etiological agents of urinary tract infection in pediatric patients and the antimicrobial resistance pattern plus biofilm producing profile of the isolates. METHODS: The prospective study was conducted in Alka Hospital, Nepal with 353 clean catch urine samples from children. It was obtained during July 2014 to January 2015 which were first cultured by semi-quantitative method, followed by antimicrobial susceptibility testing and biofilm production assay on Congo red agar...
July 3, 2018: Journal of Nepal Health Research Council
Gita Khakurel, Rajat Kayastha, Sanat Chalise, Prabin K Karki
BACKGROUND: Hyperlipidemia is one of the important risk factor for development of cardiovascular disease in post menopausal women.Our study compared the serum lipid profile and atherogenic index of plasma between premenopausal and post menopausal women. METHODS: This was a cross sectional study conducted in Kathmandu Medical College. A total number of 194 women in the age group 30 to 60 years were studied. They include 108 postmenopausal women and 86 premenopausal controls...
July 3, 2018: Journal of Nepal Health Research Council
Laxmi Kant Khanal, Ram Prasad Adhikari, Ankita Guragain
BACKGROUND: Methicillin resistant Staphylococcus aureus is a global health challenge nowadays creating problem in antibiotic therapy. This study was aimed to generate resistance pattern of Methicillin resistant Staphylococcus aureus to various antibiotics in order to formulate antibiotic policy for control of Methicillin resistant Staphylococcus aureus in Nepal. METHODS: This was a cross-sectional study conducted at the department of Clinical Microbiology, Nepal Medical College Teaching Hospital, from April 2015 to March 2016...
July 3, 2018: Journal of Nepal Health Research Council
Sabitri Lamichhane, Nayan Manandhar, Shailendra Dhakal, Yagya Laxmi Shakya
BACKGROUND: Severe sepsis and septic shock are major causes of morbidity and mortality worldwide and need immediate medical attention. Early recognition, fluid resuscitation and early antimicrobials are the mainstays of sepsis therapy. This study analyzed the management strategies of severe sepsis and septic shock and evaluated its impact. METHODS: A prospective study was conducted on patients admitted through emergency department of Tribhuvan University Teaching Hospital of Nepal, who were diagnosed with severe sepsis and septic shock...
July 3, 2018: Journal of Nepal Health Research Council
Simrin Kafle, Bandana Pradhan
BACKGROUND: Makwanpur district was declared Open Defecation Free in 2013 as the movement started in Nepal since 2003 to address the high burden of diarrhoeal disease among under five children. As the water supply, sanitation and hygiene situation of the district is not known after the declaration, the need for this study was visualized. METHODS: It was a cross sectional study among randomly sampled 178 households using interview and observation. Water, sanitation and hygiene situation was assessed in terms of related facilities, knowledge and practices of mothers...
July 3, 2018: Journal of Nepal Health Research Council
Anup Ghimire, Shyam Sundar Budhathoki, Surya Raj Niraula, Abha Shrestha, Paras K Pokharel
BACKGROUND: Injuries are a problem worldwide in all occupations. Welders are exposed to many hazards at work resulting in a variety of health problems including injuries at work. This study was conducted to find out the prevalence and factors associated with injuries among welders in Dharan city of eastern Nepal. METHODS: A cross sectional study was conducted among 86 welders in Dharan city. Occurrence of injury in past 2 weeks and past 12 months were recorded. Data regarding sociodemographic along with occupational characteristics was collected using semi structured questionnaire...
July 3, 2018: Journal of Nepal Health Research Council
Binod Kumar Aryal, Mohammad Daud, Ambika Thapa, Anita Mahotra, Sudip Ale Magar, Chandra Kumari Malla
BACKGROUND: Non-communicable Diseases are an alarming public health emergency in Nepal. Owing to the risk of NCD's in Nepal, Government of Nepal has developed a Multisectoral Action Plan for Non-communicable Disease 2014-2020 and has adopted the World Health Organization Package of Essential Non-communicable Disease protocol. Prior for its implementation in Nepal, baseline study has been carried out to assess the status of health facilities in Nepal. METHODS: A descriptive cross-sectional study was carried out in Kailali and Ilam district encompassing a total of 92 health facilities...
July 3, 2018: Journal of Nepal Health Research Council
Khus Raj Dewan, Bhanumati Saikia Patowary, Subash Bhattarai, Gaurav Shrestha
BACKGROUND: Barrett's esophagus a is metaplasia of normal squamous cells that line the lower part of the esophagus and carries a major risk for adenocarcinoma of esophagus. In Asian population, the prevalence of Barrett's esophagus and adenocarcinoma are less common than in Western countries but has been increasing. METHODS: This is a hospital based descriptive study comprising of 120 consecutive patients with symptoms of gastroesophagial reflux disease belonging to both sexes of any age group...
July 3, 2018: Journal of Nepal Health Research Council
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