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Recent Patents on Nanotechnology

Erfaneh Ghassami, Jaleh Varshosaz, Mohsen Minaiyan, Mehrab Nasirikenari, Seyed Mohammad Hoseini
BACKGROUND: Docetaxel is a notably efficient anticancer drug administered for several types of malignancies including ovarian cancer. However, various side effects caused either by nonspecific distribution of the active ingredient or by high contents of Tween 80 and ethanol in the currently marketed formulations, could even deprive the patients of the treatment. OBJECTIVES: In the current study, a novel targeted delivery system composed of Ecoflex® polymeric nanoparticles loaded with docetaxel and equipped with HER-2 specific aptemer molecules were evaluated regarding blood and tissue toxicity, and biodistribution...
November 28, 2018: Recent Patents on Nanotechnology
Reena Sheoran, Sukhbir Lal Khokra, Viney Chawla, Harish Dureja
BACKGROUND: During past decades' liposomes have emerged as efficient carriers for drugs, diagnostics, vaccines, nutrients and other bioactive agents. Liposomes, the spherical vesicles consisting of phospholipids bilayer have the ability to encapsulate both lipophilic and hydrophilic drugs. Extensive studies have been done in the past for investigating a number of drugs and genes for controlled release with liposomal formulation. Liposomes have also been investigated for their use in cancer treatment...
November 26, 2018: Recent Patents on Nanotechnology
Nalini Neethu, Tanushree Choudhury
BACKGROUND: Amphoteric membranes such as Titania Pillared Clay (TiPILC) membranes exhibit different charges at different pH ranges, subsequently show efficient separation for cationic and anionic organic pollutants in wastewater based on solution pH. The structural properties of such membranes determine their permeability and selectivity to a large extent. The present work is initiated to explore the possibility of enhancing the surface area of TiPILC membranes by grafting with 3-aminopropyltriethoxysilane...
October 29, 2018: Recent Patents on Nanotechnology
Wang Yaru, Xu Lan, Sui Jianhua, Fan Chenxu
BACKGROUND: Salicylic acid (SA), used as an important component in a lot of skin care products, has been reported widely. And because of large specific surface area, high porosity and good surfactivity, electrospun drug-loaded nanofibers have been widely used in various applications including wound dressing, tissue engineering and drug release. Particularly, the electrospun SA loaded porous nanofibers could be fabricated by regulating electrospinning (ES) parameters, and the release property of SA from nanofibers could be improved by the porous structure...
October 29, 2018: Recent Patents on Nanotechnology
Gayatri Patel, Bindu Kumari N Yadav
In recent years, researchers have been used polymeric nanofibers for various drug delivery and tissue engineering scaffolds applications. Nanofibers exhibit a wide range of unique features and properties, such as the simplicity of their fabrication, the diversity of materials suitable for processing into fibers, possession of high surface area and a complex pore structure. Nanofibers possess effective drug-loading capacity and targeting, controlled release as well as stability that have attracted much attention for their application for drug delivery...
October 17, 2018: Recent Patents on Nanotechnology
Parijat Pandey, Deepika Purohit, Harish Dureja
BACKGROUND: Pharmacokinetic issues and poor solubility in water are the most important concern of numerous recently developed chemical entities. OBJECTIVE: The drugs which are poorly soluble in water demonstrate numerous formulating troubles in conventional dosage forms and the low bio-availability is the critical problem linked with it. A nanosponge is an emerging technology which can overcome these problems and precisely control the release rates of controlled drug delivery...
September 24, 2018: Recent Patents on Nanotechnology
M Mirzaee, G Behzadi Pour
In this study, the ultracapacitor has been fabricated based on the BaTiO3/PEDOT: PSS separator film and polyvinyl alcohol (PVA) electrolyte. On the paper-substrate was coated a film of the graphite nanoparticles (GNPs) as an electrode. The GNPs and surface morphology of the separator, electrolyte and electrode have been characterized using transmission electron microscopy (TEM) and scanning electron microscopy (SEM) respectively. The specific capacitance of the ultracapacitor was measured using cyclic voltammetry and galvanostatic techniques...
September 24, 2018: Recent Patents on Nanotechnology
Chia-Wei Jui, Amy J C Trappey, Chien-Chung Fu
Nanotechnology, like 3D printing, is one of the richest fields in research and progress in the past few years. Two Photon Polymerization (TPP) technology allows the 3D printing of nanoscale objects, so the nanoscale additive manufacturing has been no longer the thing in the future. This research investigates related US patent documents through the claim-based approach. By virtue of systematic analysis of the claims of patent documents, we can explicitly define technical features of patent document and the accurate patent classification, monitor the direction of enterprises' patent application portfolio and effectively grasp the trend of technological development of important manufacturers related to this technology...
August 17, 2018: Recent Patents on Nanotechnology
Chia-Wei Jui, Amy J C Trappey, Chien-Chung Fu
Nanostructure is necessary for the existing industrial application, future development of technology or manufacturing of advanced products. Regarding the requirements of industrial technology on large area and pattern refinement, the bottleneck of lithography technique is also the key to development. The mask-less laser interference lithography can produce large area exposure and define periodic nanoscale surface pattern in the spatially periodic manner to effectively lower the cost. This research investigates related US patent documents and the findings of patent review in this research show the structure architecture of this technique has different forms, and the beam splitter architecture has advantages and application potentials on the extensive requirements of complex periodic structure...
August 6, 2018: Recent Patents on Nanotechnology
Guillermo Foladori, Eduardo Robles-Belmont, Edgar Ramon Arteaga-Figueroa, Richard Appelbaum, Edgar Zayago-Lau
This paper examines nanotechnology patents in Mexico. First, we identify nanotechnology patents and their growth between 1993 and 2014; considering those patents in nanotechnology where at least one assignee has a Mexican address. Second, we applied a methodology to allocate each patent to the most likely potential economic sector of application. The procedure can be replicated for other countries. The main conclusion is that although there is a significant registration of patents in nanotechnology in Mexico, most of them are oriented towards basic research and came out of public research centers, which raises doubts about the connection to the private sector and a short term application in commercial goods...
August 2, 2018: Recent Patents on Nanotechnology
Aline Marques Ferreira Linhares, Rafaela Lora Grando, Cristiano Piacsek Borges, Fabiana Valeria da Fonseca
BACKGROUND: Membrane separation is an established technological process, and since 1980s, it has been used commercially at large industrial plants worldwide. Water and wastewater disinfection is one of the applications of membrane technologies, but fouling and biofouling are still a challenge for the sector. The use of silver nanoparticles in membranes has attracted research interest because of their biocidal action. METHODS: This technology foresight study investigates the academic literature and patenting activity to map out the technological progress and difficulties in the area...
February 14, 2018: Recent Patents on Nanotechnology
Masoud Negahdary, Hossein Heli
BACKGROUND: Nanotechnology has opened new windows for biomedical researches and treatment of diseases. Nanostructures with flower-like shapes (nanoflowers) which have exclusive morphology and properties have been interesting for many researchers. METHODS: In this review, various applications of nanoflowers in biomedical researches and patents from various aspects have been investigated and reviewed. RESULTS: Nanoflowers attracted serious attentions in whole biomedical fields such as cardiovascular diseases, microbiology, sensors and biosensors, biochemical and cellular studies, cancer therapy, healthcare, etc...
February 14, 2018: Recent Patents on Nanotechnology
Dorsa Golestaneh, Jaleh Varshosaz
BACKGROUND: L-asparaginase is a drug of choice in the treatment of Hodgkin's lymphoma and acute lymphoblastic leukemia. Production of its bioconjugates can increase its half-life, stability and decrease its immunogenicity. OBJECTIVE: The aim of the present study was to immobilize this drug on silica nanoparticles by two different cross-linking agents. METHOD: The drug was conjugated to nanoparticles by two cross-linking agents; 1-ethyl-3-(3- dimethylaminopropyl) carboiimide HCl (EDC) or glutaraldehyde...
February 14, 2018: Recent Patents on Nanotechnology
Pawan Kumar Mishra, Kyriaki Giagli, Dimitrios Tsalagkas, Harshita Mishra, Sushma Talegaonkar, Vladimír Gryc, Rupert Wimmer
BACKGROUND: Wood science and nanomaterials science interact together in two different aspects; a) fabrication of lignocellulosic nanomaterials derived from wood and plant-based sources and b) surface or bulk wood modification by nanoparticles. In this review, we attempt to visualize the impact of nanoparticles on the wood coating and preservation treatments based on a thorough registration of the patent databases. METHOD: The study was carried out as an overview of the scientifically most followed trends on nanoparticles utilization in wood science and wood protection depicted by recent universal filed patents...
February 14, 2018: Recent Patents on Nanotechnology
Aleksander Sesek, Andrej Zemva, Janez Trontelj
BACKGROUND: The THz sensors using microbolometers as a sensing element are reported as one of the most sensitive room-temperature THz detectors suitable for THz imaging and spectroscopic applications. Microbolometer detectors are usually fabricated using different types of the MEMS technology. The patent for the detection system presented in this paper describes a method for microbolometer fabrication using a standard CMOS technology with advanced micromachining techniques. The measured sensitivity of the sensors fabricated by the patented method is 1000 V/W at an optimal frequency and is determined by the performance of a double-dipole antenna and quarter-wavelength resonant cavity...
February 14, 2018: Recent Patents on Nanotechnology
Lorenzo Torrisi, Nancy Restuccia, Irene Paterniti
BACKGROUND: Gold nanoparticles, 5-20 nm in diameter, were generated with a pulsed Nd: YAG laser at 1010 W/cm2 at solution concentrations ranging between 1-100 mg/ml. The incremental X-ray contrast imaging using gold nanoparticles was investigated and measured. The study was performed with the aim to enhance the massive absorption coefficient of X-ray radiation in the tumor for medical image quality and to improve traditional X-ray radiotherapy or proton therapy. A simulation of proton therapy improvement was conducted using a human ocular melanoma model, placed 3 cm behind the eye lens, and testing 60 MeV protons...
February 14, 2018: Recent Patents on Nanotechnology
Javier Maira, Javier Etxabe, Pedro A Serena
Nanoscience and nanotechnology made their appearance in the scientific scene at a time when both the economy of Spain and the Spanish Research and Innovation System were experiencing strong growth. This circumstance resulted in a remarkable development of nanoscience and nanotechnology especially in universities and public research institutions such as the Spanish National Research Council (Consejo Superior de Investigaciones Científicas-CSIC). However, this development in academia has not been reflected in a similar increment in the transfer of knowledge to the productive sector despite several efforts and initiatives were launched...
February 14, 2018: Recent Patents on Nanotechnology
Parijat Pandey, Harish Dureja
BACKGROUND: Cancer is a major problem which has claimed so many lives throughout the world. Although a number of resources have been utilized for the development of cancer therapeutics, no effective cure has been found so far. OBJECTIVE: Therefore, the need for looking at evolving technologies has become very important to get a solution to this problem. Among these, nanotechnology has got so much popularity and became feasible in the past few years. Nanotechnology is presently used as the most preferable drug delivery platform for cancer therapy...
2018: Recent Patents on Nanotechnology
Kunti Shah, Vijay Kumar Parmar
BACKGROUND: Cocrystals of active pharmaceutical ingredient has been of interest in the field of pharmaceutical research due to their potential for tailoring the physicochemical properties of pharmaceutical molecules. The increase in number of cocrystals screening experiments being reported and simultaneously the draft guidelines issued from regulatory bodies on pharmaceutical cocrystals provide the evidence of the acceptance of cocrystals in the drug development. This review presents the numerous patents addressing the key properties of an active pharmaceutical ingredient namely solubility and stability towards varied environmental conditions, being modified using suitable coformer and appropriate cocrystallization technique...
2018: Recent Patents on Nanotechnology
Elena A Glazkova, Olga V Bakina, Marat I Lerner, Alexandr V Pervikov
BACKGROUND: Recent advances in nanotechnology make it possible to create nanomaterials with novel microstructure and unique physicochemical properties. Different structures of nanoparticles of immiscible elements can be synthesized using chemical, mechanochemical or physical methods. The present review is devoted to contemporary state of the studies on the methods to produce bimetallic nanoparticles formed of immiscible metals. METHODS: We undertook a structured search of bibliographic databases for peer-reviewed research literature using a focused review question and inclusion/exclusion criteria...
2018: Recent Patents on Nanotechnology
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