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American Journal of Disaster Medicine

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https://www.readbyqxmd.com/read/28140443/onset-and-duration-of-intravenous-and-intraosseous-rocuronium-in-hypovolemic-swine
#1
Miguel Nemeth, George N Williams, Debbie Prichard, Angie McConnico, Don Johnson, Michael Loughren
OBJECTIVE: Compare the onset and duration of rocuronium administered via the intravenous (IV), and intraosseous (IO) routes in a hypovolemic swine model. DESIGN: Prospective, between subjects, experimental study. SETTING: Vivarium. SUBJECTS: Yorkshire-cross swine (N = 8). INTERVENTION: Electromyography (EMG) amplitudes were recorded at baseline and for every 15 seconds after administering 1.2 mg/kg of rocuronium via IV or IO routes to hypovolemic swine...
2016: American Journal of Disaster Medicine
https://www.readbyqxmd.com/read/28140442/the-effects-of-sternal-intraosseous-and-intravenous-administration-of-amiodarone-in-a-hypovolemic-swine-cardiac-arrest-model
#2
Samuel Smith, Bradley Borgkvist, Teara Kist, Jason Annelin, Don Johnson, Robert Long
OBJECTIVE: This study compared the effects of amiodarone via sternal intraosseous (SIO) and intravenous (IV) routes on return of spontaneous circulation (ROSC), time to ROSC, concentration maximum (Cmax), time to maximum concentration (Tmax), and mean concentrations over time in a hypovolemic cardiac arrest model. DESIGN: Prospective, between subjects, randomized experimental design. SETTING: TriService Research Facility. SUBJECTS: Yorkshire-cross swine (n = 28)...
2016: American Journal of Disaster Medicine
https://www.readbyqxmd.com/read/28140441/effects-of-humerus-intraosseous-versus-intravenous-amiodarone-administration-in-a-hypovolemic-porcine-model
#3
Cpt Monica M Holloway, Cpt Shannan L Jurina, Cpt Joshua D Orszag, Lt George R Bragdon, Lt Rustin D Green, Jose C Garcia-Blanco, Brian E Benham, Ltc Timothy S Adams, Don Johnson
OBJECTIVE: To compare the effects of amiodarone administration by humerus intraosseous (HIO) and intravenous (IV) routes on return of spontaneous circulation (ROSC), time to maximum concentration (Tmax), maximum plasma drug concentration (Cmax), time to ROSC, and mean concentrations over time in a hypovolemic cardiac arrest model. DESIGN: Prospective, between subjects, randomized experimental design. SETTING: TriService Research Facility. SUBJECTS: Yorkshire-cross swine (n = 28)...
2016: American Journal of Disaster Medicine
https://www.readbyqxmd.com/read/28140440/the-effects-of-tibial-intraosseous-versus-intravenous-amiodarone-administration-in-a-hypovolemic-cardiac-arrest-procine-model
#4
Kathryn Hampton, Eric Wang, Jerome Ivan Argame, Tom Bateman, William Craig, Don Johnson
OBJECTIVE: This study compared the effects of amiodarone via tibial intraosseous (TIO) and intravenous (IV) routes on return of spontaneous circulation (ROSC), time to ROSC, maximum drug concentration (Cmax), time to maximum concentration (Tmax), and mean concentrations over time in a hypovolemic cardiac arrest model. DESIGN: Prospective, between subjects, randomized experimental design. SETTING: TriService Research Facility. SUBJECTS: Yorkshire-cross swine (n = 28)...
2016: American Journal of Disaster Medicine
https://www.readbyqxmd.com/read/28140439/effects-of-tibial-and-humerus-intraosseous-administration-of-epinephrine-in-a-cardiac-arrest-swine-model
#5
Ltc Denise Beaumont, Asal Baragchizadeh, Charles Johnson, Don Johnson
OBJECTIVE: Compare maximum concentration (Cmax), time to maximum concentration (Tmax), mean serum concentration of epinephrine, return of spontaneous circulation (ROSC), time to ROSC, and odds of survival relative to epinephrine administration by humerus intraosseous (HIO), tibial intraosseous (TIO), and intravenous (IV) routes in a swine cardiac arrest model. DESIGN: Prospective, between subjects, randomized experimental design. SETTING: TriService Research Facility...
2016: American Journal of Disaster Medicine
https://www.readbyqxmd.com/read/28140438/the-comparison-of-humeral-intraosseous-and-intravenous-administration-of-vasopressin-on-return-of-spontaneous-circulation-and-pharmacokinetics-in-a-hypovolemic-cardiac-arrest-swine-model
#6
COMPARATIVE STUDY
Mark H Wimmer, Kenneth Heffner, Michael Smithers, Richard Culley, Jennifer Coyner, Michael Loughren, Don Johnson
INTRODUCTION: The American Heart Association (AHA) recommends intravenous (IV) or intraosseous (IO) vasopressin in Advanced Cardiac Life Support (ACLS). Obtaining IV access in hypovolemic cardiac arrest patients can be difficult, and IO access is often obtained in these life threatening situations. No studies have been conducted to determine the effects of humeral IO (HIO) access with vasopressin in the return of spontaneous circulation (ROSC). Our study compared the kinetics of vasopressin and ROSC with HIO with IV access in the hypovolemic swine model...
2016: American Journal of Disaster Medicine
https://www.readbyqxmd.com/read/28140437/pharmacokinetics-of-sternal-intraossesous-atropine-administration-in-normovolemic-and-hypovolemic-swine
#7
Mark Cornell, Jaime Kelbaugh, Brian Todd, Krista Christianson, Kevin Grayson, Joseph O'Sullivan, Don Johnson, Michael Loughren
OBJECTIVE: Characterize and compare the pharmacokinetics of atropine administered via the sternal intraosseous (IO) route in a normovolemic and hypovolemic swine model. DESIGN: Prospective, experimental study. SETTING: Vivarium. SUBJECTS: Yorkshire-cross swine (N = 12). INTERVENTION: Atropine was administered via the sternal IO route to normovolemic and hypovolemic swine. Blood samples were drawn at regular intervals after atropine administration and analyzed for plasma atropine concentration...
2016: American Journal of Disaster Medicine
https://www.readbyqxmd.com/read/28140436/en-route-intraosseous-access-performed-in-the-combat-setting
#8
Shelia Savell, Alejandra G Mora, Crystal A Perez, Vikhyat S Bebarta, Maj Joseph K Maddry
OBJECTIVE: To describe and compare vascular access practices used by en route care providers during medical evacuation (MEDEVAC). DESIGN: This was a retrospective cohort study. Medical records of US military personnel injured in combat and transported by MEDEVAC teams were queried. PATIENTS: The subjects were transported by military en route care providers, in the combat theater during Operation Enduring Freedom (OEF) between January 2011 and March 2014...
2016: American Journal of Disaster Medicine
https://www.readbyqxmd.com/read/28134420/effects-of-tibial-and-humerus-intraosseous-and-intravenous-vasopressin-in-porcine-cardiac-arrest-model
#9
Timothy S Adams, Dawn Blouin, Don Johnson
OBJECTIVE: Compare maximum concentration (Cmax), time to maximum concentration (Tmax), mean serum concentration of vasopressin, return of spontaneous circulation (ROSC), time to ROSC, and odds of survival relative to vasopressin administration by tibial intraosseous (TIO), humerus intraosseous (HIO), and intravenous (IV) routes in a hypovolemic cardiac arrest model. DESIGN: Prospective, between subjects, randomized experimental design. SETTING: TriService Research Facility...
2016: American Journal of Disaster Medicine
https://www.readbyqxmd.com/read/28134419/the-effects-of-sternal-and-intravenous-vasopressin-administration-on-pharmacokinetics
#10
Donald J Vallier, Ashley D Torrence, Robinson Stevens, Peta Noreen Arcinue, Don Johnson
OBJECTIVE: Purposes of this study were to compare intravenous (IV) and sternal intraosseous (SIO) administration of vasopressin relative to concentration maximum (Cmax), time to maximum concentration (Tmax), and mean concentration in a cardiac arrest model. DESIGN: Prospective, between subjects, randomized experimental design. SETTING: Vivarium. SUBJECTS: Yorkshire-cross swine (N = 16) INTERVENTION: Swine were anesthetized, placed into cardiac arrest, and after 2 minutes, cardiopulmonary resuscitation was initiated...
2016: American Journal of Disaster Medicine
https://www.readbyqxmd.com/read/28134418/effects-of-tibial-intraosseous-and-intravenous-administration-of-hextend-on-time-of-administration-and-hemodynamics-in-a-hypovolemic-swine-model
#11
James Wilson, Alex Passmore, Sephra Leger, Johnathon Lannan, Michael Bentley, Don Johnson
OBJECTIVE: To determine if there were significant differences between the tibial intraosseous (TIO) and intravenous (IV) administration of Hextend relative to time and in hemodynamics in a hypovolemic model. SETTING: Vivarium. SUBJECTS: Yorkshire swine; sample size was based on a power of 80 percent, α of 0.05, and a large effect size of 0.6. Swine were randomly assigned to one of three groups: TIO (n = 7), IV (n = 7), and control (n = 7)...
2016: American Journal of Disaster Medicine
https://www.readbyqxmd.com/read/28134417/effects-of-intravenous-sternal-and-humerus-intraosseous-administration-of-hextend-on-time-of-administration-and-hemodynamics-in-a-hypovolemic-swine-model
#12
Dawn Blouin, Brian T Gegel, Don Johnson, Jose C Garcia-Blanco
OBJECTIVE: To determine if there were significant differences among humerus intraosseous (HIO), sternal intraosseous (SIO), and intravenous (IV) administration of 500 mL Hextend in hemodynamics or administration time in a hypovolemic swine model. SETTING: Vivarium. SUBJECTS: Yorkshire swine; sample size was based on a large effect size of 0.5, an α of 0.05, and a power of 80 percent Swine were randomly assigned to one of four groups: HIO (n = 9), SIO (n = 9), IV (n = 9), and control (n = 9)...
2016: American Journal of Disaster Medicine
https://www.readbyqxmd.com/read/28134416/comparison-of-the-effects-of-sternal-and-tibial-intraosseous-administered-resuscitative-drugs-on-return-of-spontaneous-circulation-in-a-swine-model-of-cardiac-arrest
#13
Mara O'Sullivan, Andre Martinez, Audrey Long, Michelle Johnson, Dawn Blouin, Arthur D Johnson, James M Burgert
OBJECTIVE: Compare vasopressin, amiodarone, and epinephrine administration by sternal intraosseous (SIO), tibial intraosseous (TIO), and intravenous (IV) routes in a swine model of cardiac arrest. DESIGN: Prospective, randomized, between subjects, experimental design. SETTING: Laboratory. SUBJECTS: Male Yorkshire-cross swine (N = 35), seven per group. INTERVENTION: Swine were randomized to SIO, TIO, IV, cardiopulmonary resuscitation (CPR) with defibrillation, or CPR-only groups...
2016: American Journal of Disaster Medicine
https://www.readbyqxmd.com/read/28134415/a-primer-on-intraosseous-access-history-clinical-considerations-and-current-devices
#14
James M Burgert
OBJECTIVE: Intraosseous (IO) access is a method recommended by the American Heart Association and the European Resuscitation Council to administer resuscitative drugs and fluids when intravenous (IV) access cannot be rapidly or easily obtained. Many clinicians have limited knowledge or experience with the IO route. The purpose of this review was to provide the reader with a succinct review of the history, clinical considerations, and devices associated with IO access. DESIGN: Narrative review...
2016: American Journal of Disaster Medicine
https://www.readbyqxmd.com/read/28134414/intraosseous-vascular-access-in-disasters-and-mass-casualty-events-a-review-of-the-literature
#15
James M Burgert
OBJECTIVE: The intraosseous (IO) route of vascular access has been increasingly used to administer resuscitative fluids and drugs to patients in whom reliable intravenous (IV) access could not be rapidly or easily obtained. It is unknown that to what extent the IO route has been used to gain vascular access during disasters and mass casualty events. The purpose of this review was to examine the existing literature to answer the research question, "What is the utility of the IO route compared to other routes for establishing vascular access in patients resulting from disasters and mass casualty events?" DESIGN: Keyword-based online database search of PubMed, CINAHL, and the Cochrane Database of Systematic Reviews...
2016: American Journal of Disaster Medicine
https://www.readbyqxmd.com/read/28102535/circus-disaster-case-report-response-and-review-of-injuries
#16
Nicholas Asselin, Lawrence Proano, Kenneth Williams, Robert Partridge
Circus acts with human artists performing acrobatic feats are a popular spectator pastime in the United States and in international venues. There is little data in the literature regarding injuries sustained during circus acts. Some injuries are minor, but others can be serious, or even fatal. This article describes a recent circus disaster, a review of the relevant literature, and an analysis of the disaster response.
2016: American Journal of Disaster Medicine
https://www.readbyqxmd.com/read/28102534/evacuation-performance-evaluation-tool
#17
Sharon Farra, Elaine T Miller, Matthew Gneuhs, Nathan Timm, Gengxin Li, Ashley Simon, Whittney Brady
OBJECTIVE: Hospitals conduct evacuation exercises to improve performance during emergency events. An essential aspect in this process is the creation of reliable and valid evaluation tools. The objective of this article is to describe the development and implications of a disaster evacuation performance tool that measures one portion of the very complex process of evacuation. DESIGN: Through the application of the Delphi technique and DeVellis's framework, disaster and neonatal experts provided input in developing this performance evaluation tool...
2016: American Journal of Disaster Medicine
https://www.readbyqxmd.com/read/28102533/hospital-incident-command-first-responders-or-receiving-centers
#18
Brian Fletcher, Amanda Knight, Brandy Pockrus, Matthew J Wain, Kathy Lehman-Huskamp
OBJECTIVES: (1) Propose a conceptual model of an alternative hospital incident management system (HIMS) that integrates concepts used by emergency operations centers (EOCs). (2) Compare HIMS to the standard hospital incident command system (HICS) model. DESIGN: A quasi-experimental study was performed. Two identical tabletop incident scenarios were presented, one utilizing HICS and one using HIMS. Participants completed postexercise surveys for each tabletop. Surveys contained both knowledge and satisfaction questions...
2016: American Journal of Disaster Medicine
https://www.readbyqxmd.com/read/28102532/time-to-epinephrine-in-out-of-hospital-cardiac-arrest-a-retrospective-analysis-of-intraosseous-versus-intravenous-access
#19
Elliot M Ross, Julian Mapp, Chetan Kharod, David A Wampler, Christopher Velasquez, David A Miramontes
INTRODUCTION: The 2015 advanced cardiac life support update continues to advocate administering epinephrine during cardiac arrest. The goal of our study is to determine if prehospital intraosseous (IO) access results in shorter time to epinephrine than prehospital peripheral intravenous (PIV) access. METHODS: The out-of-hospital cardiac arrest (OHCA) database of a large, urban, fire-based emergency medical services system was searched for consecutive cases of OHCA between January 2013 and December 2015...
2016: American Journal of Disaster Medicine
https://www.readbyqxmd.com/read/28102531/a-systems-dynamics-approach-to-the-efficacy-of-oxime-therapy-for-mild-exposure-to-sarin-gas
#20
Daniel J Droste, Michael L Shelley, Jeffery M Gearhart, David M Kempisty
The use of nerve agents such as sarin is as much a threat today as any other time in our history. The events in Syria in 2013 are proof of this. "The Obama administration asserted Sunday for the first time that the Syrian government used the nerve gas sarin to kill more than 1,400 people (August 21, 2013) in the world's gravest chemical weapons attack in 25 years." With these recent events clear in our mind, we must focus on the horrific nature of these chemical agents to devise a strategy that will enable first responders to counteract these insidious chemicals...
2016: American Journal of Disaster Medicine
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