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Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology

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https://www.readbyqxmd.com/read/30543028/urinary-gadolinium-levels-after-contrast-enhanced-mri-in-individuals-with-normal-renal-function-a-pilot-study
#1
Dalia Alwasiyah, Christine Murphy, Paul Jannetto, Melanie Hogg, Michael C Beuhler
INTRODUCTION: Gadolinium-based contrast agents (GBCA) have been used to enhance magnetic resonance imaging (MRI) since 1985. Recently, the media and online groups have voiced concerns about gadolinium deposition in patients with normal renal function based on "elevated" urinary gadolinium levels. The determination of increased urinary gadolinium levels is based on reference ranges developed in individuals with normal renal function who were never exposed to GBCA. Studies suggest an elevated gadolinium urinary elimination greater than 72 h post GBCA scan...
December 12, 2018: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
https://www.readbyqxmd.com/read/30539383/a-review-on-ingested-cyanide-risks-clinical-presentation-diagnostics-and-treatment-challenges
#2
REVIEW
Tara B Hendry-Hofer, Patrick C Ng, Alyssa E Witeof, Sari B Mahon, Matthew Brenner, Gerry R Boss, Vikhyat S Bebarta
Cyanide, a metabolic poison, is a rising chemial threat and ingestion is the most common route of exposure. Terrorist organizations have threatened to attack the USA and international food and water supplies. The toxicokinetics and toxicodynamics of oral cyanide are unique, resulting in high-dose exposures, severe symptoms, and slower onset of symptoms. There are no FDA-approved therapies tested for oral cyanide ingestions and no approved intramuscular or oral therapies, which would be valuable in mass casualty settings...
December 11, 2018: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
https://www.readbyqxmd.com/read/30511215/articles-you-might-have-missed
#3
Charlotte Goldfine, Mark Neavyn
No abstract text is available yet for this article.
December 3, 2018: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
https://www.readbyqxmd.com/read/30499040/evaluating-the-patient-with-reported-gadolinium-associated-illness
#4
REVIEW
Tatyana Lyapustina, Charlotte Goldfine, Sean Rhyee, Kavita M Babu, Matthew K Griswold
INTRODUCTION: Gadolinium-based contrast agents (GBCAs) have been increasingly used in clinical practice since their introduction in the 1980s. Recently, increased public attention has been given to patients who report new symptoms following GBCA exposure. This review details the current knowledge surrounding GBCAs, with a focus on the known and proposed disease states that may be associated with GBCAs. Recommendations for the appropriate clinical workup of a patient suspected of having symptoms attributable to gadolinium exposure are included...
November 29, 2018: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
https://www.readbyqxmd.com/read/30488297/study-of-factors-contributing-to-scorpion-envenomation-in-arizona
#5
Bethany K Bennett, Keith J Boesen, Sharyn A Welch, A Min Kang
INTRODUCTION: Arizona has the highest incidence of scorpion envenomation reported to US poison control centers (PCCs). Most cases reported are from a residence, but specific details are limited. METHODS: Specialists at Arizona's two PCCs prospectively completed the Factors of Envenomation in Arizona Residences Survey (FEARS) for residential scorpion exposures reported during 4-week periods in the summer and winter. Based on these results, a second questionnaire, FEARS-2, targeting indoor residential exposures was then administered...
November 28, 2018: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
https://www.readbyqxmd.com/read/30478808/responsible-attention-to-conflicts-of-interest-enhances-the-credibility-of-published-scholarship
#6
EDITORIAL
Mark B Mycyk
No abstract text is available yet for this article.
November 26, 2018: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
https://www.readbyqxmd.com/read/30411236/impact-of-targeted-temperature-management-on-ed-patients-with-drug-overdose-related-cardiac-arrest
#7
Sharaf Khan, Chad M Meyers, Suzanne Bentley, Alex F Manini
INTRODUCTION: Drug overdose is the leading cause of non-traumatic out-of-hospital cardiac arrest (OHCA) among young adults. This study investigates whether targeted temperature management (TTM) improves hospital survival from presumed overdose-related cardiac arrest. METHODS: Retrospective chart review of consecutive cardiac arrests presenting to an urban tertiary care hospital ED from 2011 to 2015. ED patients with cardiac arrest were included if < 50 years old, and excluded if there was a non-overdose etiology (e...
November 8, 2018: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
https://www.readbyqxmd.com/read/30377951/pharmacologic-treatment-of-opioid-use-disorder-a-review-of-pharmacotherapy-adjuncts-and-toxicity
#8
REVIEW
Michael S Toce, Peter R Chai, Michele M Burns, Edward W Boyer
Opioid use disorder continues to be a significant source of morbidity and mortality in the USA and the world. Pharmacologic treatment with methadone and buprenorphine has been shown to be effective at retaining people in treatment programs, decreasing illicit opioid use, decreasing rates of hepatitis B, and reducing all cause and overdose mortality. Unfortunately, barriers exist in accessing these lifesaving medications: users wishing to start buprenorphine therapy require a waivered provider to prescribe the medication, while some states have no methadone clinics...
October 30, 2018: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
https://www.readbyqxmd.com/read/30353415/articles-you-may-have-missed
#9
Kristine Nanagas, Robert Avera, Andrea Purpura, Jillian Murphy, Louise Kao
No abstract text is available yet for this article.
October 23, 2018: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
https://www.readbyqxmd.com/read/30353414/the-effect-of-a-medical-toxicology-inpatient-service-in-an-academic-tertiary-care-referral-center
#10
Andrew M King, Shooshan Danagoulian, Michael Lynch, Nathan Menke, Yijia Mu, Melissa Saul, Michael Abesamis, Anthony F Pizon
INTRODUCTION: Morbidity and mortality from poison- and drug-related illness continue to rise in the USA. Medical toxicologists are specifically trained to diagnose and manage these patients. Inpatient medical toxicology services exist but their value-based economic benefits are not well established. METHODS: This was a retrospective study where length of stay (LOS) and payments received between a hospital with an inpatient medical toxicology service (TOX) and a similar hospital in close geographic proximity that does not have an inpatient toxicology service (NONTOX) were compared...
October 23, 2018: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
https://www.readbyqxmd.com/read/30276621/comment-on-pesticide-poisoned-patients-can-they-be-used-as-potential-organ-donors
#11
LETTER
Israel Rubinstein, Douglas L Feinstein
No abstract text is available yet for this article.
October 1, 2018: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
https://www.readbyqxmd.com/read/30276620/correction-to-the-toxicology-investigators-consortium-case-registry-the-2017-annual-report
#12
Lynn A Farrugia, Sean H Rhyee, Sharan L Campleman, Bryan Judge, Louise Kao, Anthony Pizon, Lauren Porter, Anne M Riederer, Timothy Wiegand, Diane P Calello, Paul M Wax, Jeffrey Brent
Please note the Collaborators for this article listed in the Acknowledgements.
October 1, 2018: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
https://www.readbyqxmd.com/read/30094774/the-toxicology-investigators-consortium-case-registry-the-2017-annual-report
#13
Lynn A Farrugia, Sean H Rhyee, Sharan L Campleman, Bryan Judge, Louise Kao, Anthony Pizon, Lauren Porter, Anne M Riederer, Timothy Wiegand, Diane Calello, Paul M Wax, Jeffrey Brent
The Toxicology Investigators Consortium (ToxIC) Case Registry was established by the American College of Medical Toxicology in 2010. The Registry collects data from participating sites with the agreement that all bedside medical toxicology consultations will be entered. The objective of this eighth annual report is to summarize the Registry's 2017 data and activity with its additional 7577 cases. Cases were identified for inclusion in this report by a query of the ToxIC database for any case entered from 1 January to 31 December 2017...
September 2018: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
https://www.readbyqxmd.com/read/30066311/reviewing-the-record-medical-record-reviews-for-medical-toxicology-research
#14
EDITORIAL
Jaiva Larsen, Mark B Mycyk, Trevonne M Thompson
No abstract text is available yet for this article.
September 2018: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
https://www.readbyqxmd.com/read/29956117/extracorporeal-cardiopulmonary-resuscitation-after-diphenhydramine-ingestion
#15
Sonia Labarinas, Kristen Meulmester, Spencer Greene, James Thomas, Manpreet Virk, Gwen Erkonen
INTRODUCTION: Diphenhydramine is a widely used first-generation histamine (H1 ) antagonist that can be obtained without prescription in many countries. Massive ingestions can result in severe toxicity and even death. We describe a case of diphenhydramine overdose leading to cardiac arrest, cardiopulmonary resuscitation (CPR), and extracorporeal membrane oxygenation (ECMO) cannulation for refractory ventricular fibrillation, a process we refer to as extracorporeal cardiopulmonary resuscitation (ECPR)...
September 2018: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
https://www.readbyqxmd.com/read/29926389/the-virtual-toxicology-journal-club-the-dissemination-and-discussion-of-noteworthy-manuscripts-using-twitter
#16
Peter R Chai, Anne-Michelle Ruha, Kelly E Wong, Derek L Monette, Meghan B Spyres, Jeff Lapoint, Howard Greller, Mark B Mycyk
BACKGROUND: Twitter-based chat groups (tweetchats) structured as virtual journal clubs have been demonstrated to provide value to learners. In order to promote topics in medical toxicology, we developed the #firesidetox tweetchat as a virtual journal club to discuss and disseminate topics in medical toxicology. METHODS: A group of medical toxicologists from the American College of Medical Toxicology (ACMT) Public Affairs Committee and editorial board of the Journal of Medical Toxicology (JMT) developed a quarterly one hour tweetchat featuring JMT manuscripts...
September 2018: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
https://www.readbyqxmd.com/read/29907949/cholinergic-crisis-caused-by-cholinesterase-inhibitors-a-retrospective-nationwide-database-study
#17
Hiroyuki Ohbe, Taisuke Jo, Hiroki Matsui, Kiyohide Fushimi, Hideo Yasunaga
INTRODUCTION: In contrast to information on the effects of organophosphate, pesticide, or environmental exposures, data on cholinergic crisis caused by pharmaceutical cholinesterase inhibitors are sparse. The present study aimed to describe the characteristics, demographics, and mortality of patients with cholinergic crisis caused by pharmaceutical cholinesterase inhibitors using a nationwide inpatient database in Japan. METHODS: We identified patients diagnosed with cholinergic crisis as a result of taking cholinesterase inhibitor medications in the Japanese Diagnosis Procedure Combination inpatient database from July 2010 to March 2016...
September 2018: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
https://www.readbyqxmd.com/read/29858745/machine-learning-to-predict-detect-and-intervene-older-adults-vulnerable-for-adverse-drug-events-in-the-emergency-department
#18
Kei Ouchi, Charlotta Lindvall, Peter R Chai, Edward W Boyer
Adverse drug events (ADEs) are common and have serious consequences in older adults. ED visits are opportunities to identify and alter the course of such vulnerable patients. Current practice, however, is limited by inaccurate reporting of medication list, time-consuming medication reconciliation, and poor ADE assessment. This manuscript describes a novel approach to predict, detect, and intervene vulnerable older adults at risk of ADE using machine learning. Toxicologists' expertise in ADE is essential to creating the machine learning algorithm...
September 2018: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
https://www.readbyqxmd.com/read/29845507/telemedicine-delivery-and-successful-reimbursement-in-toxicology
#19
Peter W Crane, Timothy J Wiegand, Michael Kamali, Marilynn Reif, Rose Wratni, Ronald Montante, Tracey Loveland
INTRODUCTION: Telemedicine and its use in medical toxicology have existed for some time. There are varied definitions, but existing ones center on using currently available forms of audio, video, and internet communications to provide "real-time" patient care. Definitions have historically limited reimbursement but recently expanded CMS guidelines have improved this. Here we describe our experience with telemedicine and reimbursement. METHODS: A retrospective study was conducted of all toxicology and billing reimbursement for fiscal year 2016 for a solo Medical Toxicology service...
September 2018: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
https://www.readbyqxmd.com/read/29785474/medical-toxicology-fellowship-training-is-available-to-applicants-from-many-specialties
#20
EDITORIAL
Louise Kao, Anthony Pizon
No abstract text is available yet for this article.
September 2018: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
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