Jack P M Andrews, Shruti S Joshi, Evangelos Tzolos, Maaz B Syed, Hayley Cuthbert, Livia E Crica, Neus Lozano, Emmanuel Okwelogu, Jennifer B Raftis, Lorraine Bruce, Craig A Poland, Rodger Duffin, Paul H B Fokkens, A John F Boere, Daan L A C Leseman, Ian L Megson, Phil D Whitfield, Kerstin Ziegler, Seshu Tammireddy, Marilena Hadjidemetriou, Cyrill Bussy, Flemming R Cassee, David E Newby, Kostas Kostarelos, Mark R Miller
Graphene oxide nanomaterials are being developed for wide-ranging applications but are associated with potential safety concerns for human health. We conducted a double-blind randomized controlled study to determine how the inhalation of graphene oxide nanosheets affects acute pulmonary and cardiovascular function. Small and ultrasmall graphene oxide nanosheets at a concentration of 200 μg m- 3 or filtered air were inhaled for 2 h by 14 young healthy volunteers in repeated visits...
February 16, 2024: Nature Nanotechnology