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Nature Nanotechnology

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https://www.readbyqxmd.com/read/29988049/graphene-quantum-dots-prevent-%C3%AE-synucleinopathy-in-parkinson-s-disease
#1
Donghoon Kim, Je Min Yoo, Heehong Hwang, Junghee Lee, Su Hyun Lee, Seung Pil Yun, Myung Jin Park, MinJun Lee, Seulah Choi, Sang Ho Kwon, Saebom Lee, Seung-Hwan Kwon, Sangjune Kim, Yong Joo Park, Misaki Kinoshita, Young-Ho Lee, Seokmin Shin, Seung R Paik, Sung Joong Lee, Seulki Lee, Byung Hee Hong, Han Seok Ko
Though emerging evidence indicates that the pathogenesis of Parkinson's disease is strongly correlated to the accumulation1,2 and transmission3,4 of α-synuclein (α-syn) aggregates in the midbrain, no anti-aggregation agents have been successful at treating the disease in the clinic. Here, we show that graphene quantum dots (GQDs) inhibit fibrillization of α-syn and interact directly with mature fibrils, triggering their disaggregation. Moreover, GQDs can rescue neuronal death and synaptic loss, reduce Lewy body and Lewy neurite formation, ameliorate mitochondrial dysfunctions, and prevent neuron-to-neuron transmission of α-syn pathology provoked by α-syn preformed fibrils5,6 ...
July 9, 2018: Nature Nanotechnology
https://www.readbyqxmd.com/read/29967460/metallic-supercurrent-field-effect-transistor
#2
Giorgio De Simoni, Federico Paolucci, Paolo Solinas, Elia Strambini, Francesco Giazotto
In their original formulation of superconductivity, the London brothers predicted1 the exponential suppression of an electrostatic field inside a superconductor over the so-called London penetration depth2-4 , λL . Despite a few experiments indicating hints of perturbation induced by electrostatic fields5-7 , no clue has been provided so far on the possibility to manipulate metallic superconductors via the field effect. Here, we report field-effect control of the supercurrent in all-metallic transistors made of different Bardeen-Cooper-Schrieffer superconducting thin films...
July 2, 2018: Nature Nanotechnology
https://www.readbyqxmd.com/read/29967459/low-voltage-electrostatic-modulation-of-ion-diffusion-through-layered-graphene-based-nanoporous-membranes
#3
Chi Cheng, Gengping Jiang, George Philip Simon, Jefferson Zhe Liu, Dan Li
Ion transport in nanoconfinement differs from that in bulk and has been extensively researched across scientific and engineering disciplines1-4 . For many energy and water applications of nanoporous materials, concentration-driven ion diffusion is simultaneously subjected to a local electric field arising from surface charge or an externally applied potential. Due to the uniquely crowded intermolecular forces under severe nanoconfinement (<2 nm), the transport behaviours of ions can be influenced by the interfacial electrical double layer (EDL) induced by a surface potential, with complex implications, engendering unusual ion dynamics5-7 ...
July 2, 2018: Nature Nanotechnology
https://www.readbyqxmd.com/read/29967458/electric-field-control-of-magnetism-in-a-few-layered-van-der-waals-ferromagnetic-semiconductor
#4
Zhi Wang, Tongyao Zhang, Mei Ding, Baojuan Dong, Yanxu Li, Maolin Chen, Xiaoxi Li, Jianqi Huang, Hanwen Wang, Xiaotian Zhao, Yong Li, Da Li, Chuankun Jia, Lidong Sun, Huaihong Guo, Yu Ye, Dongming Sun, Yuansen Chen, Teng Yang, Jing Zhang, Shimpei Ono, Zheng Han, Zhidong Zhang
Manipulating a quantum state via electrostatic gating has been of great importance for many model systems in nanoelectronics. Until now, however, controlling the electron spins or, more specifically, the magnetism of a system by electric-field tuning has proven challenging1-4 . Recently, atomically thin magnetic semiconductors have attracted significant attention due to their emerging new physical phenomena5-13 . However, many issues are yet to be resolved to convincingly demonstrate gate-controllable magnetism in these two-dimensional materials...
July 2, 2018: Nature Nanotechnology
https://www.readbyqxmd.com/read/29941889/tailoring-sample-wide-pseudo-magnetic-fields-on-a-graphene-black-phosphorus-heterostructure
#5
Yanpeng Liu, J N B Rodrigues, Yong Zheng Luo, Linjun Li, Alexandra Carvalho, Ming Yang, Evan Laksono, Junpeng Lu, Yang Bao, Hai Xu, Sherman J R Tan, Zhizhan Qiu, Chorng Haur Sow, Yuan Ping Feng, A H Castro Neto, Shaffique Adam, Jiong Lu, Kian Ping Loh
Spatially tailored pseudo-magnetic fields (PMFs) can give rise to pseudo-Landau levels and the valley Hall effect in graphene. At an experimental level, it is highly challenging to create the specific strain texture that can generate PMFs over large areas. Here, we report that superposing graphene on multilayer black phosphorus creates shear-strained superlattices that generate a PMF over an entire graphene-black phosphorus heterostructure with edge size of tens of micrometres. The PMF is intertwined with the spatial period of the moiré pattern, and its spatial distribution and intensity can be modified by changing the relative orientation of the two materials...
June 25, 2018: Nature Nanotechnology
https://www.readbyqxmd.com/read/29941888/pathway-controlled-formation-of-mesostructured-all-dna-colloids-and-superstructures
#6
Rémi Merindol, Sebastian Loescher, Avik Samanta, Andreas Walther
DNA has traditionally been used for the programmable design of nanostructures by exploiting its sequence-defined supramolecular recognition. However, control on larger length scales or even hierarchical materials that translate to the macroscale remain difficult to construct. Here, we show that the polymer character of single-stranded DNA (ssDNA) can be activated via a nucleobase-specific lower critical solution temperature, which provides a unique access to mesoscale structuring mechanisms on larger length scales...
June 25, 2018: Nature Nanotechnology
https://www.readbyqxmd.com/read/29941887/a-heterogeneous-single-atom-palladium-catalyst-surpassing-homogeneous-systems-for-suzuki-coupling
#7
Zupeng Chen, Evgeniya Vorobyeva, Sharon Mitchell, Edvin Fako, Manuel A Ortuño, Núria López, Sean M Collins, Paul A Midgley, Sylvia Richard, Gianvito Vilé, Javier Pérez-Ramírez
Palladium-catalysed cross-coupling reactions, central tools in fine-chemical synthesis, predominantly employ soluble metal complexes despite recognized challenges with product purification and catalyst reusability1-3 . Attempts to tether these homogeneous catalysts on insoluble carriers have been thwarted by suboptimal stability, which leads to a progressively worsening performance due to metal leaching or clustering 4 . The alternative application of supported Pd nanoparticles has faced limitations because of insufficient activity under the mild conditions required to avoid thermal degradation of the substrates or products...
June 25, 2018: Nature Nanotechnology
https://www.readbyqxmd.com/read/29921945/publisher-correction-nanobiophotonics-nature-inspired-sensors
#8
Wolfgang Fink
In the version of this News and Views article originally published, in the author's e-mail address, the domain was incorrectly given as 'e-mail.arizona.edu'; it should have read 'email.arizona.edu'. This has now been corrected in the online versions.
June 19, 2018: Nature Nanotechnology
https://www.readbyqxmd.com/read/29921944/getting-to-the-brain
#9
Maria Giuseppina Baratta
No abstract text is available yet for this article.
June 19, 2018: Nature Nanotechnology
https://www.readbyqxmd.com/read/29915275/taking-upconversion-to-lase-in-microcavity
#10
Gungun Lin, Dayong Jin
No abstract text is available yet for this article.
June 18, 2018: Nature Nanotechnology
https://www.readbyqxmd.com/read/29915274/energy-harvesting-from-lukewarm-photons
#11
Philippe Ben-Abdallah
No abstract text is available yet for this article.
June 18, 2018: Nature Nanotechnology
https://www.readbyqxmd.com/read/29915273/nanogap-near-field-thermophotovoltaics
#12
Anthony Fiorino, Linxiao Zhu, Dakotah Thompson, Rohith Mittapally, Pramod Reddy, Edgar Meyhofer
Conversion of heat to electricity via solid-state devices is of great interest and has led to intense research of thermoelectric materials1,2 . Alternative approaches for solid-state heat-to-electricity conversion include thermophotovoltaic (TPV) systems where photons from a hot emitter traverse a vacuum gap and are absorbed by a photovoltaic (PV) cell to generate electrical power. In principle, such systems may also achieve higher efficiencies and offer more versatility in use. However, the typical temperature of the hot emitter remains too low (<1,000 K) to achieve a sufficient photon flux to the PV cell, limiting practical applications...
June 18, 2018: Nature Nanotechnology
https://www.readbyqxmd.com/read/29915272/pre-adsorption-of-antibodies-enables-targeting-of-nanocarriers-despite-a-biomolecular-corona
#13
Manuel Tonigold, Johanna Simon, Diego Estupiñán, Maria Kokkinopoulou, Jonas Reinholz, Ulrike Kintzel, Anke Kaltbeitzel, Patricia Renz, Matthias P Domogalla, Kerstin Steinbrink, Ingo Lieberwirth, Daniel Crespy, Katharina Landfester, Volker Mailänder
To promote drug delivery to exact sites and cell types, the surface of nanocarriers is functionalized with targeting antibodies or ligands, typically coupled by covalent chemistry. Once the nanocarrier is exposed to biological fluid such as plasma, however, its surface is inevitably covered with various biomolecules forming the protein corona, which masks the targeting ability of the nanoparticle. Here, we show that we can use a pre-adsorption process to attach targeting antibodies to the surface of the nanocarrier...
June 18, 2018: Nature Nanotechnology
https://www.readbyqxmd.com/read/29915271/continuous-wave-upconverting-nanoparticle-microlasers
#14
Angel Fernandez-Bravo, Kaiyuan Yao, Edward S Barnard, Nicholas J Borys, Elizabeth S Levy, Bining Tian, Cheryl A Tajon, Luca Moretti, M Virginia Altoe, Shaul Aloni, Kenes Beketayev, Francesco Scotognella, Bruce E Cohen, Emory M Chan, P James Schuck
Reducing the size of lasers to microscale dimensions enables new technologies 1 that are specifically tailored for operation in confined spaces ranging from ultra-high-speed microprocessors 2 to live brain tissue 3 . However, reduced cavity sizes increase optical losses and require greater input powers to reach lasing thresholds. Multiphoton-pumped lasers4-7 that have been miniaturized using nanomaterials such as lanthanide-doped upconverting nanoparticles (UCNPs) 8 as lasing media require high pump intensities to achieve ultraviolet and visible emission and therefore operate under pulsed excitation schemes...
June 18, 2018: Nature Nanotechnology
https://www.readbyqxmd.com/read/29915270/antibody-orientation-determines-corona-mistargeting-capability
#15
Morteza Mahmoudi
No abstract text is available yet for this article.
June 18, 2018: Nature Nanotechnology
https://www.readbyqxmd.com/read/29892019/single-layer-graphene-modulates-neuronal-communication-and-augments-membrane-ion-currents
#16
Niccolò Paolo Pampaloni, Martin Lottner, Michele Giugliano, Alessia Matruglio, Francesco D'Amico, Maurizio Prato, Josè Antonio Garrido, Laura Ballerini, Denis Scaini
The use of graphene-based materials to engineer sophisticated biosensing interfaces that can adapt to the central nervous system requires a detailed understanding of how such materials behave in a biological context. Graphene's peculiar properties can cause various cellular changes, but the underlying mechanisms remain unclear. Here, we show that single-layer graphene increases neuronal firing by altering membrane-associated functions in cultured cells. Graphene tunes the distribution of extracellular ions at the interface with neurons, a key regulator of neuronal excitability...
June 11, 2018: Nature Nanotechnology
https://www.readbyqxmd.com/read/29892018/switchable-geometric-frustration-in-an-artificial-spin-ice-superconductor-heterosystem
#17
Yong-Lei Wang, Xiaoyu Ma, Jing Xu, Zhi-Li Xiao, Alexey Snezhko, Ralu Divan, Leonidas E Ocola, John E Pearson, Boldizsar Janko, Wai-Kwong Kwok
Geometric frustration emerges when local interaction energies in an ordered lattice structure cannot be simultaneously minimized, resulting in a large number of degenerate states. The numerous degenerate configurations may lead to practical applications in microelectronics 1 , such as data storage, memory and logic 2 . However, it is difficult to achieve very high degeneracy, especially in a two-dimensional system3,4 . Here, we showcase in situ controllable geometric frustration with high degeneracy in a two-dimensional flux-quantum system...
June 11, 2018: Nature Nanotechnology
https://www.readbyqxmd.com/read/29892017/fast-thermal-relaxation-in-cavity-coupled-graphene-bolometers-with-a-johnson-noise-read-out
#18
Dmitri K Efetov, Ren-Jye Shiue, Yuanda Gao, Brian Skinner, Evan D Walsh, Hyeongrak Choi, Jiabao Zheng, Cheng Tan, Gabriele Grosso, Cheng Peng, James Hone, Kin Chung Fong, Dirk Englund
High sensitivity, fast response time and strong light absorption are the most important metrics for infrared sensing and imaging. The trade-off between these characteristics remains the primary challenge in bolometry. Graphene with its unique combination of a record small electronic heat capacity and a weak electron-phonon coupling has emerged as a sensitive bolometric medium that allows for high intrinsic bandwidths1-3 . Moreover, the material's light absorption can be enhanced to near unity by integration into photonic structures...
June 11, 2018: Nature Nanotechnology
https://www.readbyqxmd.com/read/29808001/dna-scaffolds-support-stable-and-uniform-peptide-nanopores
#19
Evan Spruijt, Samuel E Tusk, Hagan Bayley
The assembly of peptides into membrane-spanning nanopores might be promoted by scaffolds to pre-organize the structures. Such scaffolds could enable the construction of uniform pores of various sizes and pores with controlled permutations around a central axis. Here, we show that DNA nanostructures can serve as scaffolds to arrange peptides derived from the octameric polysaccharide transporter Wza to form uniform nanopores in planar lipid bilayers. Our ring-shaped DNA scaffold is assembled from short synthetic oligonucleotides that are connected to Wza peptides through flexible linkers...
May 28, 2018: Nature Nanotechnology
https://www.readbyqxmd.com/read/29795294/electric-switching-of-magnetism-in-2d
#20
Kenneth S Burch
No abstract text is available yet for this article.
May 23, 2018: Nature Nanotechnology
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