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Annals of Thoracic Medicine

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https://www.readbyqxmd.com/read/29387261/duration-of-antibiotic-therapy-for-critically-ill-patients-with-bloodstream-infections-a-retrospective-observational-in-saudi-arabia
#1
Eman Alqasim, Sameera Aljohani, Majid Alshamrani, Nick Daneman, Robert Fowler, Yaseen Arabi
No abstract text is available yet for this article.
January 2018: Annals of Thoracic Medicine
https://www.readbyqxmd.com/read/29387260/pulmonary-consequences-of-hypothyroidism
#2
Mahmood Dhahir Al-Mendalawi
No abstract text is available yet for this article.
January 2018: Annals of Thoracic Medicine
https://www.readbyqxmd.com/read/29387259/consultation-time-for-the-pulmonary-patient
#3
Abdullah Mobeireek
No abstract text is available yet for this article.
January 2018: Annals of Thoracic Medicine
https://www.readbyqxmd.com/read/29387258/description-of-a-new-rare-alpha-1-antitrypsin-mutation-in-naples-italy-pi-m-s-napoli
#4
Marco Mosella, Mariasofia Accardo, Antonio Molino, Mauro Maniscalco, Alessandro Sanduzzi Zamparelli
Alpha-1 antitrypsin deficiency is a rare and often underdiagnosed hereditary disorder, which mainly affects the Caucasian population. We report a case of a noncystic fibrosis bronchiectasis patient in the absence of emphysema associated with low serum alpha-1-antitrypsin (AAT) level, in the absence of the most common defective alleles associated with AAT deficiency (PI*S and PI*Z) but with a new mutation in heterozygosis. This mutation is characterized by the substitution in the coding region of exon 3, of a guanine (G) for a thymine (T), generating the replacement of a glutamine (Gln) by a histidine (His) in codon 212 (cod 212 GlnCAG > HisCAT), corresponds to a new S allelic variant...
January 2018: Annals of Thoracic Medicine
https://www.readbyqxmd.com/read/29387257/deciphering-a-case-of-pulmonary-hypertension-in-a-young-female-partial-anomalous-pulmonary-venous-drainage-the-culprit
#5
Hiten R Patel, Suchit Bhutani, Fayez Shamoon, Hartaj Virk
Partial anomalous pulmonary venous drainage (PAPVD) is a rare congenital cardiac defect and is associated with sinus venosus atrial septal defect. While most cases are asymptomatic, a patient can present with pulmonary hypertension (PHTN) and it can be difficult to diagnose. Here, we discuss the case of a young female with PHTN who was found to have two right-sided PAPVD. Through this case, authors try to emphasize the importance of meticulous and thorough investigation when evaluating PHTN, which allows for correct diagnosis and a timely intervention before PHTN becomes irreversible...
January 2018: Annals of Thoracic Medicine
https://www.readbyqxmd.com/read/29387256/the-effects-of-diurnal-intermittent-fasting-on-the-wake-promoting-neurotransmitter-orexin-a
#6
Aljohara S Almeneessier, Mohammed Alzoghaibi, Abdulrahman A BaHammam, Mahmoud G Ibrahim, Awad H Olaish, Samar Z Nashwan, Ahmed S BaHammam
BACKGROUND: Food restriction has been demonstrated to increase the alertness in different species and to increase the levels of the wake-promoting neurotransmitter orexin. We hypothesized that diurnal intermittent fasting (DIF) increases orexin-A levels during fasting. Therefore, we conducted this study to assess the effects of DIF, during the month of Ramadan, on orexin, while controlling for lifestyle changes that may accompany Ramadan such as sleep duration, bedtime and wake time, energy expenditure, light exposure, and food...
January 2018: Annals of Thoracic Medicine
https://www.readbyqxmd.com/read/29387255/comparison-of-positional-and-rapid-eye-movement-dependent-sleep-apnea-syndromes
#7
Fatih Uzer, Asli Bostanc─▒ Toptas, Ummuhan Okur, Selen Bozkurt, Ebru Dogrul, Murat Turhan, Aykut Cilli
AIM: We aimed to compare the clinical, epidemiological, and polysomnographic features of rapid eye movement (REM)-dependent obstructive sleep apnea syndrome (OSAS) and positional OSAS which are two separate clinical entities. METHODS: Between January 2014 and December 2015, at the Akdeniz University Medical Faculty Hospital, patients who were diagnosed REM-dependent and positional OSAS with polysomnography were retrospectively studied. RESULTS: In this study, 1727 patients were screened consecutively...
January 2018: Annals of Thoracic Medicine
https://www.readbyqxmd.com/read/29387254/admission-predictability-of-children-with-acute-asthma
#8
Maan Alherbish, Khalid F Mobaireek, Abdullah A Alangari
OBJECTIVES: We aimed to evaluate the seasonal variations of acute asthma presentation in children and the utility of the pediatric asthma score (PAS) and its components in early admission prediction. METHODS: As part of a randomized controlled trial addressing the clinical efficacy of budesonide nebulization in the treatment of acute asthma in children, the PAS was measured at baseline, 1st , 2nd , 3rd , and 4th h from the start of medications. Decision of admission was taken at or beyond the 2nd h...
January 2018: Annals of Thoracic Medicine
https://www.readbyqxmd.com/read/29387253/primary-pulmonary-lymphoepithelioma-like-carcinoma-in-singapore
#9
Chee Kiang Tay, Yang Chong Chua, Angela Takano, Madeline Yen Min Chee, Wan-Teck Lim, Cindy Lim, Mariko Siyue Koh
BACKGROUND: Primary pulmonary lymphoepithelioma-like carcinoma (PPLELC) is a rare subtype of nonsmall cell lung cancer (NSCLC) predominantly reported in East Asia. We aimed to evaluate clinical characteristics, diagnosis, treatment, and prognosis of PPLELC in Singapore. METHODS: Retrospective review of all patients diagnosed with PPLELC at our center between 2000 and 2014. RESULTS: All 28 patients were Chinese, 67.9% were female, and the median age was 58 years (range37-76 years)...
January 2018: Annals of Thoracic Medicine
https://www.readbyqxmd.com/read/29387252/graphic-warnings-and-text-warning-labels-on-cigarette-packages-in-riyadh-kingdom-of-saudi-arabia-awareness-and-perceptions
#10
Hoda Jradi, Basema Saddik
BACKGROUND: Graphic warning labels have been shown to be effective in smoking initiation and cessation and were implemented in Saudi Arabia in 2012. To date, no study has assessed the effectiveness of these labels and the Saudi population's perceptions on the effectiveness of cigarette health warning labels. METHODS: We used a cross-sectional qualitative study comprising of nine focus groups among 3 different community group members including health-care workers, adult women and adult men...
January 2018: Annals of Thoracic Medicine
https://www.readbyqxmd.com/read/29387251/cardio-autonomic-functions-and-sleep-indices-before-and-after-coronary-artery-bypass-surgery
#11
Khamis Mohammed Al-Hashmi, Mohammed A Al-Abri, Deepali S Jaju, Mirdavron Mukaddirov, Abdulnasir Hossen, Mohammed O Hassan, Mostafa Mesbah, Hilal Ali Al-Sabti
BACKGROUND: Earlier studies showed a short-term impairment of cardio-autonomic functions following coronary artery bypass grafting (CABG). There is a lack of consistency in the time of recovery from this impairment. Studies have attributed the post-CABG atrial fibrillation to preexisting obstructive sleep apnea (OSA) without an objective sleep assessment. The aim of this study was to evaluate the effect of CABG on cardio-autonomic and hemodynamic functions and on OSA indices in patients with ischemic heart disease (IHD)...
January 2018: Annals of Thoracic Medicine
https://www.readbyqxmd.com/read/29387250/an-underestimated-cause-of-chronic-cough-the-protracted-bacterial-bronchitis
#12
REVIEW
Paola Di Filippo, Alessandra Scaparrotta, Marianna Immacolata Petrosino, Marina Attanasi, Sabrina Di Pillo, Francesco Chiarelli, Angelika Mohn
Chronic cough in childhood is associated with a high morbidity and decreased quality of life. Protracted bacterial bronchitis (PBB) seems to be the second most common cause of chronic cough in children under 6 years of age. Its main clinical feature is represented by wet cough that worsens when changing posture and improves after the introduction of antibiotics. Currently, the mainstay of PBB treatment is a 2-week therapy with a high dose of antibiotics, such as co-amoxiclav, to eradicate the infection and restore epithelial integrity...
January 2018: Annals of Thoracic Medicine
https://www.readbyqxmd.com/read/29387249/chronic-obstructive-pulmonary-disease-more-than-meets-the-eye
#13
Umur Hatipo─člu
Chronic obstructive pulmonary disease (COPD) is a major health problem which had not received the attention commensurate with the magnitude of its global burden. This is finally changing with the help of a vibrant community of health-care professionals, public officials, and academic researchers. Advances in characterization of the disease, treatment options, imaging modalities, and better understanding of the comorbidities promise to revolutionize how the disease is managed. COPD should no longer augur despair among physicians and patients...
January 2018: Annals of Thoracic Medicine
https://www.readbyqxmd.com/read/29118864/rituximab-treatment-in-patients-with-systemic-sclerosis-and-interstitial-lung-disease
#14
Abdel Gaffar A Mohammed, Ammar Alshihre, Ibrahim Abdulrazag Al-Homood
There is increasing interest in rituximab (RTX) as an alternative to cyclophosphamide for the treatment of interstitial lung diseases (ILDs) associated with systemic sclerosis (SSc). However, no report has addressed its efficacy in Saudi patients with SSc-ILD. To assess the efficacy of RTX treatment in Saudi patients with SSc-ILD, hospital records were reviewed between 2013 and 2016. Four female patients received at least 4 cycles of RTX (I cycle, consisting of two infusions of 1000 mg 2 weeks apart). Pulmonary function tests (PFTs) and chest high-resolution computed tomography (HRCT) were performed before and after treatment to assess the response...
October 2017: Annals of Thoracic Medicine
https://www.readbyqxmd.com/read/29118863/a-novel-cystic-fibrosis-gene-mutation-c-2490inst-in-a-palestinian-patient-a-case-report-and-review-of-the-literature
#15
Hassan Chami, Samer Abou Arbid, Rebecca Badra, Chantal Farra
We report the case of a 19-year-old male patient of Palestinian descent, who presented with a 1-year history of recurrent Pseudomonas aeruginosa respiratory infections, weight loss, chronic diarrhea, and a normal chloride sweat test. A panel for common cystic fibrosis transmembrane conductance regulator ( CFTR ) gene mutations test was also negative. Cystic fibrosis (CF) was still clinically suspected thus, full CFTR gene sequencing was performed, which revealed a homozygous unreported mutation c.2490insT (GenBank accession number: BankIt2019289 seq1 MF167456)...
October 2017: Annals of Thoracic Medicine
https://www.readbyqxmd.com/read/29118862/thromboprophylaxis-and-mortality-among-patients-who-developed-venous-thromboembolism-in-seven-major-hospitals-in-saudi-arabia
#16
Fahad M Al-Hameed, Hasan M Al-Dorzi, Abdulelah I Qadhi, Amira Shaker, Farjah H Al-Gahtani, Fawzi F Al-Jassir, Galila F Zahir, Tarig S Al-Khuwaitir, Mohammed H Addar, Mohamed S Al-Hajjaj, Mohamed A Abdelaal, Essam Y Aboelnazar
INTRODUCTION: Venous thromboembolism (VTE) during hospitalization is a serious and potentially fatal condition. Despite its effectiveness, evidence-based thromboprophylaxis is still underutilized in many countries including Saudi Arabia. OBJECTIVE OF THE STUDY: Our objectives were to determine how often hospital-acquired VTE patients received appropriate thromboprophylaxis, VTE-associated mortality, and the percentage of patients given anticoagulant therapy and adherence to it after discharged...
October 2017: Annals of Thoracic Medicine
https://www.readbyqxmd.com/read/29118861/lung-granuloma-a-clinicopathologic-study-of-158-cases
#17
Abdullah Al-Harbi, Salman Al-Otaibi, Abdelmonim Abdulrahman, Fares Al-Jahdali, Fahad Al-Harbi, Hana Bamefleh, Majed Gamdi, Hamdan Al-Jahdali
BACKGROUND AND AIMS: A granuloma is a common pathological diagnosis in lung biopsies and is caused by a variety of etiologies. The aim of this study was to assess the etiology and frequency of different cases of lung granulomas. METHODS: The medical records of all patients who had lung granulomas between 2005 and 2013 were retrospectively reviewed. Based on the histological features of the granulomas, along with the clinical, laboratory, and radiological findings, an attempt was made to identify the etiology of the granuloma in each case...
October 2017: Annals of Thoracic Medicine
https://www.readbyqxmd.com/read/29118860/coronary-flow-reserve-is-impaired-in-patients-with-obstructive-sleep-apnea
#18
Serife Savas Bozbas, Serpil Eroglu, Berna Akinci Ozyurek, Fusun Oner Eyuboglu
STUDY OBJECTIVES: Obstructive sleep apnea (OSA) is common in adult populations. Accumulating data indicate that it is independently associated with a variety of cardiovascular diseases and has prognostic importance in affected cases. In this study, we aimed to evaluate coronary flow reserve (CFR) in patients with OSA and controls. METHODS: Sixty-one patients undergoing an overnight polysomnography were enrolled in this study. Patients with an apnea-hypopnea index (AHI) >5 were accepted as OSA group ( n = 45) and those with an AHI <5 were taken as controls ( n = 16)...
October 2017: Annals of Thoracic Medicine
https://www.readbyqxmd.com/read/29118859/pleuropulmonary-manifestation-in-patients-with-rheumatoid-arthritis-in-saudi-arabia
#19
Omer S B Alamoudi, Suzan Mansour Attar
BACKGROUND AND OBJECTIVES: Pleuropulmonary (PP) involvement in rheumatoid arthritis (RA) is associated with high morbidity and mortality. Nevertheless, limited data are available regarding lung complications in the Middle East, especially in Saudi Arabia. The objectives of the current study were to determine the prevalence of PP manifestations and to identify the associated risk factors. METHODS: This was a retrospective study involving 419 patients diagnosed at a tertiary center over a 12...
October 2017: Annals of Thoracic Medicine
https://www.readbyqxmd.com/read/29118858/characteristics-and-predictors-of-mortality-of-patients-with-hematologic-malignancies-requiring-invasive-mechanical-ventilation
#20
Hasan M Al-Dorzi, Haya Al Orainni, Faten Al Eid, Haytham Tlayjeh, Abedalrahman Itani, Ayman Al Hejazi, Yaseen M Arabi
RATIONALE: Acute respiratory failure (ARF) may complicate the course of hematologic malignancies (HMs). Our objective was to study the characteristics, outcomes and predictors of mortality of patients with HMs who required intubation for ARF. METHODS: This retrospective cohort study evaluated all patients with HMs who were admitted to the Intensive Care Unit (ICU) of King Abdul-Aziz Medical City-Riyadh between 2008 and 2013 and required invasive mechanical ventilation...
October 2017: Annals of Thoracic Medicine
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