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World Journal of Pediatrics: WJP

Zheng-Li Wang, Li-Zhong Du, Yi-Yu Chen, Lu-Quan Li, Qi Lu, Ying Liu, Lu-Ying Cao, Yu He, Jia-Lin Yu
BACKGROUND: Critical value reporting has been widely adopted by hospitals throughout the world, but there were few reports about neonatal critical values. This study aimed to analyze characteristics of the neonatal critical values considered at our center and to provide information on improving neonatal intensive care. METHODS: A retrospective study of critical values at a newborn tertiary center in China was conducted to assess neonatal critical values according to test, distribution, reporting time, patient outcome and the impact to the therapy...
September 20, 2016: World Journal of Pediatrics: WJP
Leelawadee Techasatian, Sunee Panombualert, Rattapon Uppala, Charoon Jetsrisuparb
BACKGROUND: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe lifethreatening skin conditions. The most common cause of these manifestations is medications. Beside discontinued of the culprit drug, systemic corticosteroids were used as a primary treatment option among pediatric population. This study aimed to explore causative drugs (drug group/ latent period), treaments, complications, and treatment outcome (morbidity, mortality, length of hospital stay) of SJS and TEN in children...
September 20, 2016: World Journal of Pediatrics: WJP
Firas Rinawi, Imad Kassis, Rina Tamir, Amir Kugelman, Isaac Srugo, Dan Miron
BACKGROUND: Acute bronchiolitis in infancy is considered a risk factor for recurrent wheezing episodes in childhood. The present study assessed prevalence, clinical manifestations and risk factors for recurrent wheezing events during the first 3 years of life and persistent wheezing events beyond this age in children hospitalized as young infants with acute bronchiolitis. METHODS: Two groups of children aged 6 years were included. The study group comprised 150 children with a history of hospitalization for bronchiolitis, with the first event at <6 months of age...
September 20, 2016: World Journal of Pediatrics: WJP
Zhi-Nan Sun, Dong-Lai Hu, Zhong-Mei Chen
No abstract text is available yet for this article.
September 20, 2016: World Journal of Pediatrics: WJP
Chethan Ramprasad, Rajeev Zachariah, Mark Steinhoff, Anna Simon
BACKGROUND: The rate of influenza vaccination is low for children in India. The purpose of this study is to assess parental attitudes towards influenza vaccination in South India. METHODS: Participants were parents who brought their children to the Well Baby Clinic of Christian Medical College Hospital, Vellore, India for routine immunization. Participants answered questions by written survey while waiting for their children's vaccination. RESULTS: A total of 456 surveys were completed (403 parents did not opt for trivalent influenza vaccination and 53 opted for influenza vaccination)...
August 31, 2016: World Journal of Pediatrics: WJP
Yan-Jie Huang, Xiao-Qing Yang, Wen-Sheng Zhai, Xian-Qing Ren, Yuan Sun, Ying Ding
No abstract text is available yet for this article.
August 2016: World Journal of Pediatrics: WJP
Shu-Jiong Mao, Xian-Mei Huang
No abstract text is available yet for this article.
August 2016: World Journal of Pediatrics: WJP
Nirmala Sirisena, Vajira H W Dissanayake
No abstract text is available yet for this article.
August 2016: World Journal of Pediatrics: WJP
Recep Sancak, Mehmet Halil Celiksoy
No abstract text is available yet for this article.
August 2016: World Journal of Pediatrics: WJP
Gu-Ling Qian, Fang Hong, Fan Tong, Hai-Dong Fu, Ai-Min Liu
BACKGROUND: Glutaric acidemia type I (GA-I) is a rare metabolic disorder caused by mutation of the glutaryl- CoA dehydrogenase (GCDH) gene. The occurrence of rhabdomyolysis with GA-I is extremely rare. METHODS: We reported a child with recurrent rhabdomyolysis and undiagnosed glutaric acidemia type I (GA-I). And a literature review was performed. RESULTS: A 4.5-year-old girl was admitted to our hospital due to recurrent rhabdomyolysis for 3 times within three years...
August 2016: World Journal of Pediatrics: WJP
Zi-Hao Yang, Bo-Tao Ning, Chen-Mei Zhang, Ru Lin, Sheng Ye, Tao Liu
BACKGROUND: This study aimed to discribe the experience in supporting children with refractory cardiopulmonary failure with extracorporeal membrane oxygenation (ECMO). METHODS: We retrospectively reviewed 12 children with refractory cardiopulmonary failure supported with ECMO from February 2009 to August 2015 in the Pediatric Intensive Care Unit (PICU), Children's Hospital, Zhejiang University School of Medicine. RESULTS: Seven of the 12 patients were weaned successfully from ECMO and dischaged from the hospital, with a survival rate of 58...
August 2016: World Journal of Pediatrics: WJP
Da-Hang Zhao, Wei-Wei Rao, Li Zhao, Xuan Yang, Jian-Lin Liu, Zhen-Kai Wu, Qing Du, Xiao-Yan Yang
BACKGROUND: This study was designed to determine whether the occurrence of clubfoot follows a seasonal pattern in neonates from eastern and south-eastern China and to speculate the potential etiology of clubfoot. METHODS: We reviewed 239 neonates with clubfeet during a period of 4 years as well as the monthly neonatal population of the Sixth National Population Census. Seasonal variations in terms of month of birth and severity were analyzed. RESULTS: The incidence of clubfoot in neonates from eastern and south-eastern China showed seasonal variations, and the incidence was higher in autumn with a reference to the average birth rate in this corresponding area...
August 2016: World Journal of Pediatrics: WJP
Marcin Tkaczyk, Monika Miklaszewska, Jolanta Lukamowicz, Wojciech Fendler
BACKGROUND: The role of idiopathic nephrotic syndrome (INS) in the pathogenesis of atherosclerosis in childhood has not been clearly elucidated. However, antioxidative defense in INS is thought to be imbalanced. This study aimed to assess the changes of plasma concentration of selected aminothiols in the blood of children with INS at various stages of the disease. METHODS: This cross-sectional study was conducted in 125 children aged 2-18 years. The children were divided into 4 groups: group A, early relapse (n=37); group B, early remission for 4-6 weeks from the onset (n=37); group C, late steroid-free remission (n=31); and group D, long-term remission for 2-5 years (n=20)...
August 2016: World Journal of Pediatrics: WJP
Shahid I Sheikh, Judy Pitts, Nancy A Ryan-Wenger, Karen S McCoy, Don Hayes
BACKGROUND: Exposure to household domestic animals such as cats and dogs in early life may have some role in pathogenesis of asthma. Racial differences exist in the prevalence of asthma. We hypothesized that there may also be racial differences in pet ownership in families with asthma. METHODS: A cross sectional study was conducted from June 2011 to December 2014 on 823 of 850 (97%) families of children with asthma for pet ownership. Comparisons among racial groups were done using chi square analysis and one-way analysis of variance...
August 2016: World Journal of Pediatrics: WJP
Xu-Fang Li, Yan-Xia Zhou, Lian Zhang
BACKGROUND: To observe the development of neonatal sleep among healthy infants of different conceptional age (CA) by analyzing the amplitude-integrated electroencephalography (aEEG) of their sleep-wake cycles (SWC). METHODS: Bedside aEEG monitoring was carried out for healthy newborns from 32 to 46 weeks CA between September 1, 2011 and August 30, 2012. For each aEEG tracing, mean duration of every complete SWC, number of SWC repetition within 12 hours, mean duration of each narrow and broadband of SWC, mean voltage of the upper edge and lower edge of SWC, mean bandwidth of SWC were counted and calculated...
August 2016: World Journal of Pediatrics: WJP
Amy E Caruso Brown, Edwin J Asturias, Mario Melgar, Federico A Antillon-Klussmann, Pamela Mettler, Myron J Levin
BACKGROUND: Varicella-zoster virus infection is associated with significant morbidity and mortality in immune-compromised children, despite treatment with antiviral agents. Universal varicella vaccine programs have significantly decreased this risk in many highincome countries, but in most low-income and middleincome countries, the burden of varicella in children treated for malignancy is poorly defined. METHODS: We retrospectively reviewed records of children at the National Unit of Pediatric Oncology (UNOP) in Guatemala diagnosed with varicella between January 2009 and March 2013 in order to calculate incidence of varicella and evaluate morbidity, mortality, treatment interruption, and cost...
August 2016: World Journal of Pediatrics: WJP
Sumesh Parat, Maroun Jean Mhanna
BACKGROUND: To investigate strategies used for the management of respiratory distress syndrome (RDS) and bronchopulmonary dysplasia (BPD) in extremely low birth weight (ELBW) infants. METHODS: A survey of neonatal specialists working in US academic institutions with fellowship training programs. RESULTS: Eighty percent (72/89) of the identified academic institutions had at least one physician who responded to the survey. Among respondents, 85% (171/201) agreed or strongly agreed to use continuous positive airway pressure (CPAP) initially for the management of RDS, and the majority agreed or strongly agreed to use a fraction of inspired oxygen (FiO2) ≥0...
August 2016: World Journal of Pediatrics: WJP
Han Zhang, Ming-Guo Xu, Li-Jian Xie, Min Huang, Jie Shen, Ting-Ting Xiao
BACKGROUND: Kawasaki disease (KD) has now become the leading cause of acquired heart disease among children in developed countries. This study investigated whether patients with KD have an increased risk of atherosclerosis. METHODS: Electronic databases, including PubMed, Embase and Springer link, were searched through June 1, 2015, for eligible studies. Studies were included when they met the following criteria: 1) an observational study focusing on evaluating the risk factors for atherosclerosis in patients with KD; 2) KD was diagnosed clinically according to the Japan Kawasaki Disease Research Committee or American Heart Association's diagnostic criteria; 3) the study subjects were KD patients without coronary heart disease or related cardiovascular disease (KD group) and non-KD patients as control (control group), and 4) investigation of important atherosclerosis risk factors, total cholesterol (TC), low-density lipoprotein cholesterol (LDL), triglycerides (TG), systolic blood pressure (SBP), and flowmediated dilatation (FMD)...
August 2016: World Journal of Pediatrics: WJP
Pei Xie, Li-Qun Zang, Xue-Kun Li, Qiang Shu
BACKGROUND: Function of epigenetic modifications is one of the most competitive fields in life science. Over the past several decades, it has been revealed that epigenetic modifications play essential roles in development and diseases including developmental diseases. In the present review, we summarize the recent progress about the function of epigenetic regulation, especially DNA and RNA modifications in developmental diseases. DATA SOURCES: Original research articles and literature reviews published in PubMed-indexed journals...
August 2016: World Journal of Pediatrics: WJP
Ivana Đurić-Filipović, Marco Caminati, Gordana Kostić, Đorđe Filipović, Zorica Živković
BACKGROUND: The incidence of asthma and allergic rhinitis (AR) is significantly increased, especially in younger children. Current treatment for children with asthma and allergic rhinitis include allergen avoidance, standard pharmacotherapy, and immunotherapy. Since standard pharmacotherapy is prescribed for symptoms, immunotherapy at present plays an important role in the treatment of allergic diseases. This article presents insights into the up-to-date understanding of immunotherapy in the treatment of children with allergic rhinitis and asthma...
August 2016: World Journal of Pediatrics: WJP
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