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World Journal of Pediatrics: WJP

Dervla Kelly, Alan Kelly, Tom O'Dowd, Catherine B Hayes
BACKGROUND: Taking oral antibiotics during childhood has been linked with an increased risk of childhood obesity. This study assessed any potential association in number of courses of antibiotics taken between 2-3 and 4-5 years of age and body mass trajectory up to age 5. METHODS: The study was a secondary analysis of 8186 children and their parents from the infant cohort of the Irish National Longitudinal Study of Children. Antibiotic use was measured by parental recall between ages 2-3 and 4-5...
January 12, 2019: World Journal of Pediatrics: WJP
Xiong-Fei Pan, Li Tang, Andy H Lee, Colin Binns, Chun-Xia Yang, Zhu-Ping Xu, Jian-Li Zhang, Yong Yang, Hong Wang, Xin Sun
BACKGROUND: Fetal macrosomia, defined as birth weight equal or over 4000 g, is a major concern for both neonatal and maternal health. A rapid increasing trend in fetal macrosomia is observed in different regions of China. We aimed to examine the association between fetal macrosomia and risk of childhood obesity in Western China. METHODS: All macrosomic live singletons (≥ 4000 g), and a random sample of singletons with normal birth weight (2500-3999 g) born in four districts of Chengdu, Western China, in 2011 were included in the cohort study...
January 11, 2019: World Journal of Pediatrics: WJP
Jie Shao
No abstract text is available yet for this article.
January 10, 2019: World Journal of Pediatrics: WJP
Shakif Mohammad Shakur, John Whitehall, Poonam Mudgil
BACKGROUND: Bloodstream infections (BSIs) cause significant morbidity and mortality of children worldwide. The aim of this study was to investigate BSI in children and determine the identity of causative organism and their susceptibility patterns in a metropolitan public hospital in Australia. METHODS: We retrospectively reviewed children aged 0-16 years admitted to a public hospital from January 1, 2010 to August 31, 2014 inclusive, and whose blood cultures revealed bacteraemia...
January 7, 2019: World Journal of Pediatrics: WJP
Li-Fen Ye, Yong Fan, Qiang Shu, Ru Lin
BACKGROUND: To summarize the experience of management of persistent pulmonary hypertension of the newborn (PPHN) with extracorporeal membrane oxygenation (ECMO) support. METHODS: We presented three neonates with PPHN supported by ECMO in our center. Medical records and patient management notes were retrospectively reviewed. RESULTS: For two neonates with congenital diaphragmatic hernia (CDH), diaphragm repair surgery was done under ECMO support...
January 3, 2019: World Journal of Pediatrics: WJP
Xi-Cheng Zhang, Li-Qi Shu, Xing-Sen Zhao, Xue-Kun Li
BACKGROUND: Autism spectrum disorder (ASD), a pervasive developmental neurological disorder, is characterized by impairments in social interaction and communication, and stereotyped, repetitive patterns of interests or behaviors. The mechanism of ASDs is complex, and genetic components and epigenetic modifications play important roles. In this review, we summarized the recent progresses of ASDs focusing on the genetic and epigenetic mechanisms. We also briefly discussed current animal models of ASD and the application of high-throughput sequencing technologies in studying ASD...
January 3, 2019: World Journal of Pediatrics: WJP
Guillermo Montes
BACKGROUND: To determine the prevalence of parent-reported ethnic/racial discrimination, and to determine if children with special health care needs are more likely to experience ethnic discrimination than other children who have similar family income, age, sex, race, parental education and Hispanic ethnicity. METHODS: Using the National Survey of Children's Health 2011-2012 (n = 95,677), ethnic discrimination was measured by two questions that asked "was child ever treated or judged unfairly because of his/her race or ethnic group?" and if so, how often it occurred in the last 12 months prior to the survey...
December 27, 2018: World Journal of Pediatrics: WJP
Hua-Hong Wu, Ya-Qin Zhang, Xin-Nan Zong, Hui Li
BACKGROUND: In China, as the social transformation and economic development from 1985 to 2015, children's feeding pattern has undergone some changes. So we aimed to analyze the secular trend on feeding patterns of city children in China. METHODS: All data were from a series of national survey which implemented once every 10 years in China from 1985 to 2015. We use same indexes to evaluate the feeding pattern of children in these four surveys. RESULTS: From 1985 to 2005, the exclusive breastfeeding rates in infants under 6 months of age decreased, especially in suburban areas decreased by 17...
December 11, 2018: World Journal of Pediatrics: WJP
Shirin Osouli Tabrizi, Mojgan Mirghafourvand, Abdollah Jannat Dost, Sakineh Mohammad-Alizadeh-Charandabi, Yousef Javadzadeh, Robabe Seyedi
BACKGROUND: Jaundice is a common neonatal problem. This study was conducted to determine the effect of metoclopramide on neonatal bilirubin and maternal prolactin (primary outcomes) and milk volume (secondary outcome). METHODS: This triple-blind, randomized, controlled, clinical trial was conducted on 112 mothers. The participants were assigned to the intervention (metoclopramide) and control groups (placebo) using block randomization. Ten-mg metoclopramide and placebo tablets were taken by the participants three times a day...
December 5, 2018: World Journal of Pediatrics: WJP
Nanae Tanemura, Maika Asawa, Mayuko Kuroda, Tsuyoshi Sasaki, Yoshiaki Iwane, Hisashi Urushihara
BACKGROUND: Off-label use of psychotropic prescriptions for pediatric patients has been increasing in Japan. This study sought to clarify pediatric patients' off-label use of psychotropics approved only for adults in Japan. METHODS: This retrospective study on psychotropic utilization employed a pharmaceutical health insurance claims database supplied by a pharmacy for the fiscal year 2016. Seven psychotropic drugs were examined. For each drug, we calculated the proportion of patients aged < 16 years or who were under the approved age limit set in the United States out of all patients...
November 30, 2018: World Journal of Pediatrics: WJP
Satita Jeamsripong, Sirirat Charuvanij
BACKGROUND: Musculoskeletal (MSK) complaints in children vary, ranging from benign, self-limited conditions to serious disorders. Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease, initially presenting with MSK complaints. Delayed diagnosis and appropriate treatment have an enormous impact on the long-term outcomes and the level of disability. This study aimed to identify the features distinguishing JIA among children presenting with MSK complaints and to describe the spectrum of diseases at a large, single, tertiary center...
November 29, 2018: World Journal of Pediatrics: WJP
Xiao-He Yu, Le Zhong, Jia Huang
BACKGROUND: Attention deficit hyperactivity disorder (ADHD) is a major public health problem in China. Parents of children with confirmed, or suspected ADHD often face a difficult process in making decisions concerning diagnosis and treatment. The internet is a major source of information for parents. The purpose of this study is to survey Chinese parental motivation and experience in using the internet to retrieve ADHD-related information, and how well online information is associated with making decisions...
November 26, 2018: World Journal of Pediatrics: WJP
Hidehiko Maruyama, Yuka Shibata, Xing-Ge Xia, Yun-Xia Sun, Shao-Ru He, Yushi Ito
BACKGROUND: Various differences between China and Japan in approaches to medical treatment have been noted, but a few studies have examined differences in medical decision-making, especially in neonatal care. The aim of this study was to clarify these differences by means of a questionnaire. METHODS: The subjects were physicians on the staff of NICUs in China and Japan. The study questionnaire consisted of three parts dealing with the general characteristics of the participants, questions about treatment strategies for hypothetical, critically ill infants, and general questions about the treatment of foreign patients...
November 23, 2018: World Journal of Pediatrics: WJP
Wen-Jun Shen, Gong Chen, Min Wang, Shan Zheng
BACKGROUND: Biliary atresia (BA) is the most common cause of obstructive jaundice in infants. Although the Kasai procedure has greatly improved the prognosis, most patients still need liver transplantation (LT) for long-term survival. The pathogenesis of BA has not been fully clarified, and liver fibrosis in BA is far beyond biliary obstructive cirrhosis. DATA SOURCES: Literature reviews were underwent through PubMed. Persistent inflammation, immune response, biliary epithelial-mesenchymal transition, matrix deposition, decompensated angiogenesis, and unique biliary structure development all contribute to the fibrosis process...
November 21, 2018: World Journal of Pediatrics: WJP
Robabe Seyedi, Mojgan Mirghafourvand, Abdollah Jannat Dost, Sakineh Mohammad-Alizadeh-Charandabi, Mohammad Asghari Jafarabadi, Shirin Osouli Tabrizi
BACKGROUND: Hyperbilirubinemia, which is mostly benign, is one of the most common problems in neonates. This study was conducted to draw a skin bilirubin nomogram for evaluating the risk of hyperbilirubinemia requiring treatment. METHODS: This cross-sectional study recruited 1066 healthy infants. The first transcutaneous bilirubin (TcB) measurement was performed before hospital discharge and within 12-48 h of birth. The neonates were followed up for 6 days after discharge based on their age at the time of discharge...
November 21, 2018: World Journal of Pediatrics: WJP
Nadia Dehbokri, Gholamreza Noorazar, Aida Ghaffari, Gita Mehdizadeh, Parvin Sarbakhsh, Saba Ghaffary
BACKGROUND: In this research the symptom improvement of attention-deficit hyperactivity disorder (ADHD) of children was assessed by oral vitamin D administration in Tabriz, Iran. METHODS: In this double-blind, randomized clinical trials, 96 children (2-18 years) were enrolled to placebo and vitamin D groups. Children took vitamin D pearl (50,000 IU/week) or placebo for 6 weeks. Children, who had the change in methylphenidate dosage and received any anticonvulsants and corticosteroids were excluded from the research...
November 19, 2018: World Journal of Pediatrics: WJP
Brigitta Balogh, Tamás Kovács, Amulya Kumar Saxena
INTRODUCTION: The aim of this study was to analyze the complication rates and mortality in association with different operative techniques of percutaneous endoscopic gastrostomy (PEG), age, underlying diseases and other risk factors. Moreover, analysis of the indications of PEG insertion and the underlying comorbidities was also performed. METHODS: This study performs a literature analysis of PEG-related complications in children. Literature was searched on PubMed® (1994-2017) using terms "percutaneous endoscopic gastrostomy", "complications", "mortality" and "children"...
November 19, 2018: World Journal of Pediatrics: WJP
Hao Zhou, Chun-Pei Li, Yi Huang, Xiao-Bing Zou, Xue-Rong Luo, Li-Jie Wu, Lan Zhang, Xiu Xu, Wei-Li Yan, Yi Wang
BACKGROUND: Early autism screening is of great value, but there is lack of a screening tool of early age (2-5 years) in China. The Autism Spectrum Rating Scale (ASRS, 2-5 years) is a newly developed autism screening tool in the USA. This study aimed to evaluate the reliability and validity of the translated Chinese version of ASRS (C_ASRS) in Chinese children population before its application in China for early autism screening. METHODS: Caregivers of general children aged 2-5 years from 17 kindergartens and autism spectrum disorder (ASD) cases from five special education schools in five cities were recruited to complete the C_ASRS...
November 16, 2018: World Journal of Pediatrics: WJP
Miao-Shang Su, Li Xu, Wen-Feng Pan, Chang-Chong Li
BACKGROUND: Obstructive sleep apnea (OSA) and nocturnal enuresis (NE) are common clinical problems in children. OSA and NE are thought to be interrelated, but the exact pathophysiological mechanisms are not yet clear. This review aims to explain the possible pathogenesis of NE in children with OSA. DATE SOURCES: We have retrieved all relevant original articles from Database that have been published so far, including the prevalence studies of NE and OSA in children, sleep characteristic studies that use polysomnography (PSG) to focus on children with NE, and studies on the relationship between OSA and NE...
November 16, 2018: World Journal of Pediatrics: WJP
Wei Yao, Kai Li, Kui-Ran Dong, Shan Zheng, Xian-Min Xiao
BACKGROUND: Low-risk neuroblastomas have favorable biologic characteristics. Children Oncology Group (COG) proposed that surgical resection of the primary tumor was sufficient. We evaluated the long-term prognosis of surgery alone for patients with low-risk neuroblastoma in China. METHODS: A total of 34 patients with low-risk neuroblastoma were treated in our center between Jan 2009 and Dec 2013. The medical records of these patients were reviewed. RESULTS: The primary lesion was located in the adrenal gland in 19 patients, the retroperitoneum in 5, the posterior mediastinum in 9 and the neck in 1...
November 16, 2018: World Journal of Pediatrics: WJP
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