Feng-Bin Lu, En-De Hu, Lan-Man Xu, Lu Chen, Jin-Lu Wu, Hui Li, Da-Zhi Chen, Yong-Ping Chen
A number of researches have explored the association between obesity and nonalcoholic fatty liver disease (NAFLD) liver function, histopathology, complications, genetic factors and prognosis, but the results were conflicting and inconclusive. Areas covered: In this meta-analysis, the liver function, histopathology, metabolic complications, patatin-like phospholipase domain-containing protein 3 (PNPLA3) genetic polymorphism and prognosis were compared between non-obese and obese NAFLD. Pubmed, EMBASE, Cochrane databases were searched to identify eligible studies...
April 2, 2018: Expert Review of Gastroenterology & Hepatology