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Journal of Pediatric Neurosciences

Dhruv K Agarwal, Sugat Sanyal, Eswararao Thamatapu, Prasad Krishnan
No abstract text is available yet for this article.
January 2018: Journal of Pediatric Neurosciences
Guru Dutta Satyarthee, A K Mahapatra
No abstract text is available yet for this article.
January 2018: Journal of Pediatric Neurosciences
Anil V Israni, Anirban Mandal
No abstract text is available yet for this article.
January 2018: Journal of Pediatric Neurosciences
N A Uvais
No abstract text is available yet for this article.
January 2018: Journal of Pediatric Neurosciences
Kriti S Sadana, Jatinder S Goraya
No abstract text is available yet for this article.
January 2018: Journal of Pediatric Neurosciences
Dhruv K Agarwal, Sachinkumar M Patel, Prasad Krishnan
Corpus callosal agenesis results in certain characteristic radiological appearances on magnetic resonance imaging. These classical named signs are revisited in this article.
January 2018: Journal of Pediatric Neurosciences
Jayendra R Gohil, Tushar S Agarwal
Pancytopenia secondary to levetiracetam administration is infrequent but possible. Here, we report a case of pancytopenia associated with levetiracetam in a 4-month-old infant. However, increased incidence of upper respiratory tract infections (URTIs) has been reported frequently. It appears that URTI is a heralding side effect of pancytopenia and tip of the iceberg.
January 2018: Journal of Pediatric Neurosciences
Anjuna Reghunath, Rohini Gupta Ghasi, Abhimanyu Bhargava, Narinder Kumar Bhambri
Posterior quadrantic dysplasia (PQD) is a rare cause of pediatric intractable epilepsy. It is a sporadic cortical development malformation that involves the posterior three lobes of a single hemisphere and spares the frontal cortex. Very few cases have been reported in the literature, mostly as anecdotal reports or as a part of large series of refractory epilepsy. It is essential to know about this lesser known entity and differentiate it from other more common similar anomalies such as multilobar cortical dysplasia and hemimegalencephaly as new motor-sparing neurosurgical disconnective procedures have led to dramatically reduced mortality and morbidity rates, apart from gifting the affected children a better quality of life...
January 2018: Journal of Pediatric Neurosciences
Archana Ramgopal, Aravind Thavamani, Abdulla Ghori
Mycoplasma pneumoniae is a microbe known to affect numerous organ systems, and in particular, can cause neurological manifestations. We describe an otherwise healthy child who presented with acute onset intractable headache with magnetic resonance imaging (MRI) findings consistent with posterior reversible encephalopathy syndrome (PRES), a neurological manifestation that presents with headache, vision changes, altered mental status, or seizures. Our patient did not have any of the common etiologies for PRES reported but tested positive for acute M...
January 2018: Journal of Pediatric Neurosciences
Prem Chand, Pooja Manglani, Qalab Abbas
Isolated hemimegalencephaly (iHME) is a rare form of congenital malformation of cortical development characterized by enlargement of all or part of one cerebral hemisphere. It typically presents with intractable seizures, developmental delay, contralateral hemiparesis, and hemianopia. We report a case of an 18-month-old girl who presented first with focal seizures at tenth day of life, with no other physical or behavioral abnormality. Initial EEG showed excessive sharp EEG transients more over the right hemisphere; repeated EEG showed spikes, polyspikes, sharps, and slow wave discharges predominately over the right hemisphere...
January 2018: Journal of Pediatric Neurosciences
Anjaneya S Kathait, Paulo Puac, Mauricio Castillo
Maple syrup urine disease (MSUD) is a rare autosomal-recessive disorder that affects branched-chain amino acid (BCAA) metabolism. It is characterized by accumulation of BCAAs and corresponding branched-chain keto acids of leucine, isoleucine, and valine in plasma, urine, and cerebrospinal fluid. Leucine is toxic to brain cells, leading to cytotoxic edema affecting the myelinated white matter, and involving the corticospinal tracts, thalami, globus palladi, midbrain, dorsal brain stem, and cerebellum. We present a neonate with the classic subtype of MSUD and its imaging features on magnetic resonance imaging...
January 2018: Journal of Pediatric Neurosciences
Dhinesh Baskaran, Arif Khan, Nahin Hussain
A young girl with L-dopa responsive dystonia showed significant improvements in motor function but had ongoing complaints of neuropsychological difficulties. A neuropsychological evaluation was undertaken to understand the nature of her difficulties. Intellectual function, attention, executive function, and academic attainment were assessed using published psychometric tests. Verbal and non-verbal reasoning was found to be age appropriate. Particular difficulties were identified with working memory, visual selective attention, dual attention, and processing speed which were having a significant impact upon the child and her family...
January 2018: Journal of Pediatric Neurosciences
Satish Kannan, A Sendil Kumar, S Syamala
Epidermoid cysts are slow-growing benign tumors that represent less than 1-2% of all intracranial tumors. They are even rarer in supratentorial intraparenchymal location accounting for 2% of all intracranial epidermoid cysts. We present a rare case of pediatric supratentorial intraparenchymal epidermoid cyst with its variable radiographic features, surgical management, histopathology, and a review of the literature.
January 2018: Journal of Pediatric Neurosciences
Sachidanand Gautam, Anubhav Sharma
Human echinococcus is caused by tapeworm, Echinococcus granulosus , which forms larval cysts in the human tissue. Incidence in the cerebral form is only 1-2%. This localization can be associated with the involvement of other organs such as liver or lung or may be an isolated infestation of the brain or spinal column. Surgical removal of the intact and unruptured cyst is advised to prevent local recurrence that may require further surgery and long-term treatment with parasiticidal agents. We report three cases who presented with headache, vomiting, hemiparesis with decreased visual acuity, and convulsions...
January 2018: Journal of Pediatric Neurosciences
Luis Rafael Moscote-Salazar, Willem Guillermo Calderon-Miranda, Ray Vicente Deluquez Baute, Amit Agrawal, Guru Dutta Satyarthee, Johana Maraby-Salgado, Huber Said Padilla-Zambrano, Daniela Lopez-Cepeda, Alfonso Pacheco-Hernandez, Andrei F Joaquim
The case of a term newborn diagnosed with Aicardi-Goutières syndrome, a rare encephalopathy in our environment, with Mendelian inheritance pattern, characterized by a set of nonspecific neurological symptoms associated with typical findings of intracerebral calcifications. The case is presented with diagnostic imaging, in addition to elevated levels of interferon alpha and cerebrospinal fluid lymphocytosis.
January 2018: Journal of Pediatric Neurosciences
Jagdish P Meena, Menka Yadav, Aditya K Gupta, Prashant Ramteke, Priyanka Naranje, Rachna Seth
Extramedullary leukemia is common in pediatric acute myeloid leukemia (AML) and occurs as a solid tumor (myeloid sarcoma). We report a case of a child who presented with acute onset of paraparesis and found to have intracranial and paravertebral mass; subsequently, he was diagnosed as having AML on tissue biopsy. He was started on AML treatment protocol, and later he was in remission and myeloid sarcoma got cleared from intracranial and paravertebral region. Timely diagnosis and initiation of treatment are essential to improve survival in such cases...
January 2018: Journal of Pediatric Neurosciences
Satyashiva Munjal, Amit Srivastava, Kavita Kapoor, Veer Singh Mehta
A 2-year-old boy was presented to us with right-side hemiparesis after trivial fall. Diffusion-weighted magnetic resonance imaging showed an infarct in left basal ganglia and thalamic region. Secondary causes of stroke were ruled out. The child was managed conservatively. Basal ganglia infarct secondary to minor trauma is a rare event. Possible mechanisms leading to such an event and its management are discussed.
January 2018: Journal of Pediatric Neurosciences
Mohammed Aloddadi, Safar Alshahrani, Ibrahim Alnaami
The management of hydrocephalus represents a neurosurgical challenge. Ventriculoperitoneal (VP) shunts are usually the treatment of choice for hydrocephalus. However, when VP shunt is not an option, ventriculoatrial (VA) shunt becomes a second choice. VA shunts have special complications such as postoperative neck hematomas, shunt nephritis, and migration of the distal segment. There are two main techniques for the retrieval of migrated VA shunt: either by retrieval of the broken segment by thoracotomy, which is highly invasive, or by transvenous approach...
January 2018: Journal of Pediatric Neurosciences
Ashutosh Gupta, Charu Gupta, Monika Sachan, Sandeep Singh
Neurofibromatosis type 2 is a rare neurocutaneous syndrome characterized by the development of multiple nervous system tumors. This disorder is also called multiple inherited schwannomas, meningiomas, and ependymomas syndrome. In this report, we discuss the clinical and magnetic resonance imaging findings in a 17-year-old patient with neurofibromatosis type 2, who had extensive cranial nerves involvement (3rd-12th cranial nerves) along with spinal involvement. It is very rare to find tumors affect nearly all cranial nerves (namely 3rd-12th nerves), and their association with meningiomas and intramedullary spinal cord tumors in the same patient...
January 2018: Journal of Pediatric Neurosciences
Varsha H Chauhan, Richa Chaudhary, Payal Meshram
Acute disseminated encephalomyelitis (ADEM) is an acute monophasic syndrome caused by immune-mediated inflammatory demyelination, often associated with immunization or viral illness. ADEM is associated with multiple neurological symptoms. We are presenting a case of ADEM with stroke, which responded very well to high-dose steroids. Here we report a case of ADEM, masquerading as pediatric stroke.
January 2018: Journal of Pediatric Neurosciences
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