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Clinical Interventions in Aging

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https://www.readbyqxmd.com/read/27895475/transcranial-direct-current-stimulation-improves-the-qt-variability-index-and-autonomic-cardiac-control-in-healthy-subjects-older-than-60-years
#1
Gianfranco Piccirillo, Cristina Ottaviani, Claudia Fiorucci, Nicola Petrocchi, Federica Moscucci, Claudia Di Iorio, Fabiola Mastropietri, Ilaria Parrotta, Matteo Pascucci, Damiano Magrì
BACKGROUND: Noninvasive brain stimulation technique is an interesting tool to investigate the causal relation between cortical functioning and autonomic nervous system (ANS) responses. OBJECTIVE: The objective of this report is to evaluate whether anodal transcranial direct current stimulation (tDCS) over the temporal cortex influences short-period temporal ventricular repolarization dispersion and cardiovascular ANS control in elderly subjects. SUBJECTS AND METHODS: In 50 healthy subjects (29 subjects younger than 60 years and 21 subjects older than 60 years) matched for gender, short-period RR and systolic blood pressure spectral variability, QT variability index (QTVI), and noninvasive hemodynamic data were obtained during anodal tDCS or sham stimulation...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/27895474/efficacy-of-l-carnitine-supplementation-on-frailty-status-and-its-biomarkers-nutritional-status-and-physical-and-cognitive-function-among-prefrail-older-adults-a-double-blind-randomized-placebo-controlled-clinical-trial
#2
M Badrasawi, Suzana Shahar, A M Zahara, R Nor Fadilah, Devinder Kaur Ajit Singh
BACKGROUND: Frailty is a biological syndrome of decreased reserve and resistance to stressors due to decline in multiple physiological systems. Amino acid deficiency, including L-carnitine, has been proposed to be associated with its pathophysiology. Nevertheless, the efficacy of L-carnitine supplementation on frailty status has not been documented. Thus, this study aimed to determine the effect of 10-week L-carnitine supplement (1.5 g/day) on frailty status and its biomarkers and also physical function, cognition, and nutritional status among prefrail older adults in Klang Valley, Malaysia...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/27895473/calf-raise-senior-a-new-test-for-assessment-of-plantar-flexor-muscle-strength-in-older-adults-protocol-validity-and-reliability
#3
Helô-Isa André, Filomena Carnide, Edgar Borja, Fátima Ramalho, Rita Santos-Rocha, António P Veloso
PURPOSE: This study aimed to develop a new field test protocol with a standardized measurement of strength and power in plantar flexor muscles targeted to functionally independent older adults, the calf-raise senior (CRS) test, and also evaluate its reliability and validity. PATIENTS AND METHODS: Forty-one subjects aged 65 years and older of both sexes participated in five different cross-sectional studies: 1) pilot (n=12); 2) inter- and intrarater agreement (n=12); 3) construct (n=41); 4) criterion validity (n=33); and 5) test-retest reliability (n=41)...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/27895472/safety-and-effectiveness-of-daily-teriparatide-for-osteoporosis-in-patients-with-severe-stages-of-chronic-kidney-disease-post-hoc-analysis-of-a-postmarketing-observational-study
#4
Atsushi Nishikawa, Fumito Yoshiki, Masanori Taketsuna, Kenta Kajimoto, Hiroyuki Enomoto
Teriparatide (recombinant 1-34 N-terminal sequence of human parathyroid hormone) for the treatment of osteoporosis should be prescribed with caution in patients with severe stages of chronic kidney disease (CKD). However, in clinical settings, physicians and surgeons who treat such patients have few available options. We sought to further explore the safety and effectiveness of teriparatide for the treatment of osteoporosis in Japanese patients with severe stages of CKD. This was a post hoc analysis of a postmarketing surveillance study that included patients with osteoporosis at high risk of fracture and stage 4 or 5 CKD...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/27881914/habitual-cocoa-intake-reduces-arterial-stiffness-in-postmenopausal-women-regardless-of-intake-frequency-a-randomized-parallel-group-study
#5
Takanobu Okamoto, Ryota Kobayashi, Midori Natsume, Koichi Nakazato
Arterial stiffness is substantially higher in postmenopausal than in premenopausal women. Daily cocoa intake has been shown to reduce central arterial stiffness in health adults, regardless of age; however, the effect of cocoa-intake frequency on arterial stiffness in postmenopausal women remains unclear. Therefore, the purpose of this study was to investigate the effects of cocoa-intake frequency on arterial stiffness in postmenopausal women. A total of 26 postmenopausal women (mean age ± standard deviation 64±12 years) were randomly assigned to two groups with different cocoa-intake frequencies: one group ingested 17 g of cocoa once daily except on Sundays (every-day group, n=13), and the other ingested 17 g of cocoa twice daily every other day (every-other-day group, n=13)...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/27881913/effectiveness-of-the-vital-aging-program-to-promote-active-aging-in-mexican-older-adults
#6
Neyda Ma Mendoza-Ruvalcaba, Rocío Fernández-Ballesteros
INTRODUCTION: Aging is not only a population phenomenon but also an experience and an individual reality. Vital Aging(®) is a program that considers active aging as the lifelong adaptation process of maximizing health and independence, physical and cognitive functioning, positive affect regulation and control, and social engagement. Through its different versions and editions, it has demonstrated being an effective program to promote active aging. The aim of this study is to determine the effectiveness of the "face-to-face" and "combined" versions of the program to promote active aging in Mexican older adults trial...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/27877029/comments-on-the-paper-efficacies-of-globus-pallidus-stimulation-and-subthalamic-nucleus-stimulation-for-advanced-parkinson-s-disease-a-meta-analysis-of-randomized-controlled-trials
#7
COMMENT
https://www.readbyqxmd.com/read/27877028/efficacy-of-a-trunk-orthosis-with-joints-providing-resistive-force-on-low-back-load-during-level-walking-in-elderly-persons
#8
Junji Katsuhira, Ko Matsudaira, Hiroyuki Oka, Shinno Iijima, Akihiro Ito, Tadashi Yasui, Arito Yozu
PURPOSE: The effects of lumbosacral and spinal orthoses on low back pain and gait are not exactly clear. We previously developed a trunk orthosis with joints providing resistive force on low back load to decrease such load, and confirmed its positive effects during level walking in healthy young adults. Therefore, we aimed to determine the efficacy of this trunk orthosis during level walking in healthy elderly subjects. METHODS: Fifteen community-dwelling elderly subjects performed level walking at a self-selected speed without an orthosis, with our orthosis, and with a lumbosacral orthosis...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/27877027/fatigue-as-a-long-term-risk-factor-for-limitations-in-instrumental-activities-of-daily-living-and-or-mobility-performance-in-older-adults-after-10-years
#9
Sigrid Mueller-Schotte, Nienke Bleijenberg, Yvonne T van der Schouw, Marieke J Schuurmans
OBJECTIVES: Decline in the performance of instrumental activities of daily living (IADL) and mobility may be preceded by symptoms the patient experiences, such as fatigue. The aim of this study is to investigate whether self-reported non-task-specific fatigue is a long-term risk factor for IADL-limitations and/or mobility performance in older adults after 10 years. METHODS: A prospective study from two previously conducted cross-sectional studies with 10-year follow-up was conducted among 285 males and 249 females aged 40-79 years at baseline...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/27877026/pharmaceutical-interventions-by-collaboration-between-staff-pharmacists-and-clinical-pharmacists-and-implementation-of-joint-commission-international-accreditation-standards-on-medication-use-may-optimize-pharmacotherapy-in-geriatric-patients
#10
COMMENT
https://www.readbyqxmd.com/read/27843305/does-the-use-of-acetylsalicylic-acid-have-an-influence-on-our-vision
#11
REVIEW
Katarzyna Michalska-Małecka, Agnieszka Regucka, Dorota Śpiewak, Magdalena Sosnowska-Pońska, Alfred Niewiem
PURPOSE: Acetylsalicylic acid (ASA) is one of the most commonly used drugs in the world due to its anti-inflammatory, analgesic, and antipyretic properties. This review aims to describe the relationship between acetylsalicylic acid and age-related macular degeneration (AMD) - a chronic disease that causes deterioration of visual acuity and is one of the most common ophthalmological diseases these days. METHODS: Data presented in this review were collected from both research and review articles concerning ophthalmology and pharmacology...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/27826189/behavioral-emergency-in-the-elderly-a-descriptive-study-of-patients-referred-to-an-aggression-response-team-in-an-acute-hospital
#12
Daniel Simpkins, Carmelle Peisah, Irene Boyatzis
AIM: The management of severely agitated elderly patients is not easy, and limited guidelines are available to assist practitioners. At a Sydney hospital, an Aggression Response Team (ART) comprising clinical and security staff can be alerted when a staff member has safety concerns. Our aims were to describe the patient population referred for ART calls, reasons for and interventions during ART calls, and complications following them. METHODS: Patients 65 years and older referred for ART calls in the emergency department or wards during 2014 were identified using the Incident Information Management System database and medical records were reviewed...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/27826188/response-to-depression-treatment-in-the-aging-brain-care-medical-home-model
#13
Michael A LaMantia, Anthony J Perkins, Sujuan Gao, Mary G Austrom, Cathy A Alder, Dustin D French, Debra K Litzelman, Ann H Cottingham, Malaz A Boustani
OBJECTIVE: To evaluate the effect of the Aging Brain Care (ABC) Medical Home program's depression module on patients' depression severity measurement over time. DESIGN: Retrospective chart review. SETTING: Public hospital system. PARTICIPANTS: Patients enrolled in the ABC Medical Home program between October 1, 2012 and March 31, 2014. METHODS: The response of 773 enrolled patients who had multiple patient health questionnaire-9 (PHQ-9) scores recorded in the ABC Medical Home program's depression care protocol was evaluated...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/27826187/a-prospective-study-about-the-preoperative-total-blood-loss-in-older-people-with-hip-fracture
#14
Jie-Zhou Wu, Peng-Cheng Liu, Wei Ge, Ming Cai
PURPOSE: Our study is to confirm that hemoglobin (Hb) level is significantly reduced before operation in elderly patients with hip fracture and to specify potential amounts of bleeding and Hb decline in different types of fractures. METHODS: A prospective analysis was made on the clinical data of 349 patients with both a diagnosis of hip fracture and an operative delay of greater than 72 hours between April 2014 and February 2016. Hb concentration was measured on a daily basis before the surgery...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/27822026/age-influence-on-renalase-and-catecholamines-concentration-in-hypertensive-patients-including-maintained-dialysis
#15
Edyta Zbroch, Dominika Musialowska, Ewa Koc-Zorawska, Jolanta Malyszko
BACKGROUND: Hypertension in elderly patients is one of the main problems in cardiovascular diseases. The sympathetic nervous system hyperactivity seen in older patients is a known risk factor for hypertension and other cardiovascular events as well as chronic kidney disease. Renalase, secreted by the kidney and circulated in blood, may regulate the sympathetic tone by catecholamine degradation and in this way has an impact on cardiovascular and renal complications. OBJECTIVE: To assess the impact of age on renalase and catecholamine concentration in hypertensive patients, including those on dialyses and its possible relation to blood pressure control and cardiovascular disease...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/27822025/deep-analyses-of-the-associations-of-a-series-of-biomarkers-with-insulin-resistance-metabolic-syndrome-and-diabetes-risk-in-nondiabetic-middle-aged-and-elderly-individuals-results-from-a-chinese-community-based-study
#16
Shihui Fu, Ping Ping, Leiming Luo, Ping Ye
OBJECTIVE: The current study was designed to perform deep analyses of the associations of biomarkers, including high-sensitivity C-reactive protein (hs-CRP), N-terminal prohormone of brain natriuretic peptide (NT-proBNP), and homocysteine (Hcy), with insulin resistance (IR), metabolic syndrome (MetS), and diabetes risk and evaluate the abilities of biomarkers to identify IR, MetS, and diabetes risk in Chinese community-dwelling middle-aged and elderly residents. PARTICIPANTS AND METHODS: A total of 396 participants older than 45 years underwent physical examinations and laboratory analyses following standardized protocol...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/27822024/animal-models-of-frailty-current-applications-in-clinical-research
#17
REVIEW
Alice E Kane, Sarah N Hilmer, John Mach, Sarah J Mitchell, Rafael de Cabo, Susan E Howlett
The ethical, logistical, and biological complications of working with an older population of people inherently limits clinical studies of frailty. The recent development of animal models of frailty, and tools for assessing frailty in animal models provides an invaluable opportunity for frailty research. This review summarizes currently published animal models of frailty including the interleukin-10 knock-out mouse, the mouse frailty phenotype assessment tool, and the mouse clinical frailty index. It discusses both current and potential roles of these models in research into mechanisms of frailty, interventions to prevent/delay frailty, and the effect of frailty on outcomes...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/27822023/inappropriate-nutrients-intake-is-associated-with-lower-functional-status-and-inferior-quality-of-life-in-older-adults-with-depression
#18
Agnieszka Guligowska, Małgorzata Pigłowska, Elizaveta Fife, Joanna Kostka, Bartłomiej K Sołtysik, Łukasz Kroc, Tomasz Kostka
OBJECTIVES: The study is a case-control analysis of whether depression impairs physical and cognitive functioning and quality of life, and whether there is a relationship between nutrient deficiencies and these adverse changes. PATIENTS AND METHODS: A total of 130 older subjects participated in the study: 65 with diagnosed depression (16 men and 49 women) and 65 age- and sex-matched controls without depression. All patients underwent comprehensive geriatric assessment...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/27822022/sex-specific-predictors-of-left-ventricular-diastolic-dysfunction-in-untreated-hypertension
#19
Joanna Jaroch, Olga Vriz, Zbigniew Bociąga, Caterina Driussi, Maria Łoboz-Rudnicka, Barbara Rzyczkowska, Krystyna Łoboz-Grudzień
BACKGROUND: Little is known about the sex-specific differences in left ventricular (LV) diastolic dysfunction (DD) predictors. We hypothesized that arterial stiffness (AS) may play a different role in the etiology of LV DD in hypertensive men and postmenopausal women, acting independently from other established predictors of this condition, such as age, obesity, diabetes mellitus, LV remodeling, and systolic function. OBJECTIVES: The aim of the study was to analyze the sex-specific differences in AS and other predictors of LV DD in men and postmenopausal women with untreated hypertension (HTN)...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/27799754/quality-of-life-of-women-with-breast-cancer-undergoing-radiotherapy-using-the-functional-assessment-of-chronic-illness-therapy-fatigue-questionnaire
#20
Marta Muszalik, Małgorzata Kołucka-Pluta, Kornelia Kędziora-Kornatowska, Joanna Robaczewska
OBJECTIVE: Breast cancer is one of the most common cancers in women, particularly among older women. This illness along with its treatment has a great impact on a woman's subjective opinion of her quality of life and functioning in everyday life. The aim of this research was to assess the quality of life in women undergoing radiotherapy for the treatment of breast cancer. PATIENTS AND METHODS: The research was carried out in 120 patients with breast cancer undergoing radiotherapy in the Oncological Center in Bydgoszcz, Poland...
2016: Clinical Interventions in Aging
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