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Clinical Interventions in Aging

Xing-De Wang, Li Zhou, Chao-Yu Zhu, Bin Chen, Zhong Chen, Li Wei
Purpose: Sympathovagal imbalance is a common underlying disorder in hypertension and diabetes. This study characterized autonomic nervous system function, indicated by heart rate deceleration capacity (DC) and deceleration runs (DRs), in patients with type 2 diabetes mellitus (T2DM), with or without concomitant essential hypertension. Subjects and methods: We recruited 50 healthy subjects, 50 patients with T2DM, and 95 with T2DM and essential hypertension. DC, DRs (DR2 , DR4 , and DR8 , ie, episodes of 2, 4, or 8 consecutive beat-to-beat heart rate decelerations, respectively), and heart rate variability were determined by dynamic electrocardiogram...
2018: Clinical Interventions in Aging
Huei-Ling Huang, Yea-Ing L Shyu, Wen-Chuin Hsu
Background/aims: Limited research has been conducted on agitated behavior in Taiwan and dementia among community-dwelling elderly. Therefore, this study focused on community elderly with dementia and a factor analysis of an inventory of their agitated behaviors was conducted. Patients and methods: Participants (N=221) completed the Chinese Cohen-Mansfield Agitation Inventory, community form. Item analysis and exploratory factor analysis assessed reliability, validity, and the underlying factor structure...
2018: Clinical Interventions in Aging
Maria Łoboz-Rudnicka, Joanna Jaroch, Ewa Kruszyńska, Zbigniew Bociąga, Barbara Rzyczkowska, Krzysztof Dudek, Andrzej Szuba, Krystyna Łoboz-Grudzień
Background: In recent years, there has been growing interest in the impact of gender-related factors on the function and structure of the arterial tree. The aim of our study was to identify gender-specific differences in the progression of carotid stiffness parameters with age and in the impact of risk factors on carotid stiffness. Subjects and methods: The study group included 256 subjects (mean age: 54.7 years): 134 women (52%) and 122 men (48%) with cardiovascular risk factors: hypertension, type 2 diabetes mellitus, dyslipidemia, smoking, and obesity...
2018: Clinical Interventions in Aging
Hirofumi Nagayama, Norikazu Kobayashi, Yu Ishibashi, Ryuji Kobayashi, Chika Murai, Keita Yamauchi
Purpose: The purpose of this pilot study was to determine the effectiveness and costs of the occupation-based practice for community dwelling frail elderly. Design: Pilot pre-post design without a control group. Setting: A care management center involving 37 local elderly. Subject: The final analysis included 26 frail elderly in a community dwelling center. Intervention: The intervention was occupation-based practice involving setting of client-centered goals, observation of real living situations, and provision of advice on the individual problem of real occupation...
2018: Clinical Interventions in Aging
Boaz Kahana, Jiao Yu, Eva Kahana, Kaitlyn Barnes Langendoerfer
Purpose: The purpose of this article was to examine the relative importance of patients' self-advocacy and perceived physicians' advocacy for impacting patients' satisfaction in terms of physician communication and physician-patient relationship. We also examine the influence of physicians' emotional support and patients' demographic as well as health characteristics on patients' satisfaction. Sample: Our sample includes interviews with 806 community dwelling older adults (mean age =77...
2018: Clinical Interventions in Aging
Qinglin Li, Meng Zhao, Xiaodan Wang
Objectives: To compare the differences between the Kidney Disease Improving Global Outcomes (KDIGO) criteria of the 48-hour window and the 7-day window in the diagnosis of acute kidney injury (AKI) in very elderly patients, as well as the relationship between the 48-hour and 7-day windows for diagnosis and 90-day mortality. Patients and methods: We retrospectively enrolled very elderly patients (≥75 years old) from the geriatrics department of the Chinese PLA General Hospital between January 2007 and December 2015...
2018: Clinical Interventions in Aging
Shmuel Springer, Itamar Friedman, Avi Ohry
Background: Age-related changes in coordinated movement pattern of the thorax and pelvis may be one of the factors contributing to fall risk. This report describes the feasibility of using a new thoracopelvic assisted movement device to improve gait and balance in an elderly population with increased risk for falls. Methods: In this case series, 19 older adults were recruited from an assisted living facility. All had gait difficulties (gait speed <1.0 m/s) and history of falls...
2018: Clinical Interventions in Aging
Jacek Staszewski, Renata Piusińska-Macoch, Bogdan Brodacki, Ewa Skrobowska, Adam Stępień
Background: Endothelial dysfunction (ED) is involved in the pathogenesis of cerebral small vessel disease (SVD), however, it is not clear if specific biomarkers related to ED are associated with radiological progression of SVD. Methods: A single-center, prospective cohort study was conducted among consecutive, adult patients with SVD. Logistic regression was used to analyze the association of each baseline biomarker (highest vs lowest tertile) and the MRI radiological outcome after 2 years...
2018: Clinical Interventions in Aging
Horacio Islas-Granillo, Carlo Eduardo Medina-Solís, María de Lourdes Márquez-Corona, Rubén de la Rosa-Santillana, Miguel Ángel Fernández-Barrera, Juan José Villalobos-Rodelo, César Tadeo Hernández-Martínez, José de Jesús Navarrete-Hernández, Martha Mendoza-Rodríguez
Background: Aging is one of the most prominent features in recent population dynamics around the world. As populations age, the prevalence of simultaneous chronic diseases increases, which is known as multimorbidity. Objective: The aim of the present study was to determine the prevalence of multimorbidity and associated factors in a sample of elderly Mexican subjects. Materials and methods: A cross-sectional descriptive study was performed on a convenience sample of 139 subjects aged ≥60 years...
2018: Clinical Interventions in Aging
Rainer Spiegel, Roger Kalla, Georgios Mantokoudis, Raphael Maire, Heiko Mueller, Robert Hoerr, Ralf Ihl
Background: Tinnitus and dizziness are frequent in old age and often seen as concomitant symptoms in patients with dementia. In earlier clinical trials, Ginkgo biloba extract EGb 761® was found to alleviate tinnitus and dizziness in elderly patients. Consequently, a meta-analysis was conducted to evaluate the effects of EGb 761® at a daily dose of 240 mg on tinnitus and dizziness associated with dementia. Methods: Randomized, placebo-controlled clinical trials of G...
2018: Clinical Interventions in Aging
Magdalena I Tolea, Stephanie Chrisphonte, James E Galvin
Background: Sarcopenia and obesity both negatively impact health including cognitive function. Their coexistence, however, can pose an even higher threat likely surpassing their individual effects. We assessed the relationship of sarcopenic obesity with performance on global- and subdomain-specific tests of cognition. Patients and methods: The study was a cross-sectional analysis of data from a series of community-based aging and memory studies. The sample consisted of a total of 353 participants with an average age of 69 years with a clinic visit and valid cognitive (eg, Montreal Cognitive Assessment, animal naming), functional (eg, grip strength, chair stands), and body composition (eg, muscle mass, body mass index, percent body fat) measurements...
2018: Clinical Interventions in Aging
Jiachen Luo, Liming Dai, Jianming Li, Jinlong Zhao, Zhiqiang Li, Xiaoming Qin, Hongqiang Li, Baoxin Liu, Yidong Wei
Purpose: New-onset atrial fibrillation (NOAF) is a common finding in patients with myocardial infarction (MI), but few studies are available regarding the prediction model for its risk estimation. Although Global Registry of Acute Coronary Events (GRACE) risk score (RS) has been recognized as an effective tool for the risk evaluation of clinical outcomes in patients with MI, its usefulness in the prediction of post-MI NOAF remains unclear. In this study, we sought to validate the discrimination performance of GRACE RS in the prediction of post-MI NOAF and to make a comparison with that of the CHA2 DS2 -VASc score in patients with ST-segment elevation myocardial infarction (STEMI)...
2018: Clinical Interventions in Aging
Wei Wu, Dong-Xia Li, Qing Wang, Ying Xu, Yun-Jing Cui
Objective: Low-level high-sensitivity cardiac troponin T (hs-cTnT) increases in elderly population. In this study, the relationship between hs-cTnT level and all-cause death of elderly inpatients with non-acute coronary syndrome (non-ACS) after discharge from the hospital was investigated. Materials and methods: Non-ACS patients aged >65 years admitted in the General Practice Wards and Department of Geriatrics of Fuxing Hospital Affiliated to Capital Medical University were enrolled in the study...
2018: Clinical Interventions in Aging
Hee-Won Jung, Il-Young Jang, Chang Ki Lee, Sang Soo Yu, Jae Kyoon Hwang, Chawoong Jeon, Young Soo Lee, Eunju Lee
Purpose: We aimed to describe the age- and sex-specific distributions of gait speed and to evaluate associations with longitudinal outcomes in Korean rural community-dwelling older adults. Patients and methods: A total of 1,348 people (mean age: 76 years, 55% women) in the population-based, prospective cohort of Aging Study of Pyeongchang Rural Area (ASPRA) between October 2014 and June 2017. All participants underwent a comprehensive geriatric assessment, including 4-m usual gait speed, and were followed annually...
2018: Clinical Interventions in Aging
Kyle Konis, Wendy J Mack, Edward L Schneider
A 12-week study was conducted in eight dementia care communities involving 77 participants addressing the hypothesis that an intervention of increasing indoor exposure to daylight will reduce depression and other neuropsychiatric symptoms. At four communities, staff were enlisted to increase daylight exposure by taking participants to a perimeter room with daylight exposure for socialization in the morning (8:00-10:00 AM) each day. At the other four communities, a control group were taken to a similar sized area without daylight for socialization under typical electrical lighting conditions...
2018: Clinical Interventions in Aging
Katarzyna Kotfis, Aleksandra Szylińska, Mariusz Listewnik, Marta Strzelbicka, Mirosław Brykczyński, Iwona Rotter, Maciej Żukowski
Introduction: Postoperative delirium is a common complication of cardiac surgery associated with increased mortality, morbidity, and long-term cognitive dysfunction. The aim of this study was to identify incidence and risk factors of delirium in elderly (≥65 years) and very elderly (≥80 years) patients undergoing major cardiac surgery. Materials and methods: We performed a retrospective cohort analysis of prospectively collected data from a register of the cardiac surgery department of a tertiary referral university hospital between 2014 and 2016...
2018: Clinical Interventions in Aging
Ha Yeon Kim, Sook Young Lee, Seyoon Kang, Bora Kim, Yeo Rae Moon, Ji Eun Kim
Background: Remifentanil infusion during emergence lowers cough. Effect-site concentration (Ce) of remifentanil using target-controlled infusion (TCI) has been evaluated in previous studies. Recent studies revealed the existence of sex-related differences in remifentanil Ce in young and elderly patients. Thus, there was the need to re-evaluate the effect of age in single sex. We investigated the remifentanil Ce for suppressing emergence cough in young and elderly male patients and evaluated the age-related differences...
2018: Clinical Interventions in Aging
Tomasz Nowak, Agnieszka Neumann-Podczaska, Ewa Deskur-Śmielecka, Arkadiusz Styszyński, Katarzyna Wieczorowska-Tobis
Introduction: In patients with dementia, observational scales are recommended for use in the assessment of pain. Unfortunately, their application is rare, and as a consequence pain is frequently underdiagnosed and undertreated in these types of subjects. Thus, the aim of the study was to assess analgesic treatment in nursing home residents with cognitive impairment and to delineate the relationship between pain and behavioral and psychological symptoms of dementia. Patients and methods: The research was conducted in 2 nursing home facilities in Wielkopolska, Poland...
2018: Clinical Interventions in Aging
(no author information available yet)
[This corrects the article on p. 995 in vol. 12, PMID: 28721027.].
2018: Clinical Interventions in Aging
Michael Dörks, Stefan Herget-Rosenthal, Falk Hoffmann, Kathrin Jobski
Background/aims: In 2012, the European Medicines Agency reviewed the safety of dual renin-angiotensin system (RAS) blockade because of potentially increased risks for inter alia acute kidney injury (AKI). Since residents of nursing homes are particularly vulnerable to adverse drug outcomes, the aims of our study were to describe RAS-inhibiting drug use in German nursing home residents and examine the risk of AKI associated with dual RAS blockade. Methods: Based on claims data, a nested case-control study within a cohort of RAS-inhibiting drug users was conducted...
2018: Clinical Interventions in Aging
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