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Clinical Interventions in Aging

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https://www.readbyqxmd.com/read/28053514/clinical-outcome-and-predictors-of-adverse-events-of-an-enhanced-older-adult-psychiatric-liaison-service-rapid-assessment-interface-and-discharge-newport
#1
Inderpal Singh, Priya Fernando, Jane Griffin, Chris Edwards, Kathryn Williamson, Patrick Chance
BACKGROUND: Hospitals are currently admitting an increasing number of older people, and more than one-third could have an underlying mental health problem. The existing Older Adult Mental Health (OAMH) liaison service was increasingly unable to meet the escalating needs of older and frail patients. Therefore, the service was modernized and enhanced on an "invest-to-save" principle to provide a prompt holistic assessment for older adults with mental health problems. The objective of this study was a service evaluation to appraise clinical outcome, minimize the length of stay, and measure the predictors of adverse outcomes to streamline this enhanced service...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28053513/metastatic-castration-resistant-prostate-cancer-in-very-elderly-patients-challenges-and-solutions
#2
REVIEW
Orazio Caffo, Francesca Maines, Mimma Rizzo, Stefania Kinspergher, Antonello Veccia
The treatment of elderly patients with cancer is usually viewed by clinicians as a challenge, because of the age-related decline in normal organ function and the frequent concomitant administration of multiple drugs for comorbid conditions. Clinicians therefore tend not to prescribe antineoplastic agents (mainly in the case of chemotherapy) to elderly patients, with the fear of excess toxicity leading to an unfavorable cost:benefit ratio. The cutoff age defining a cancer patient as elderly is usually 70 years, but over the last 10 years clinicians have paid more attention to functional status, as evaluated by means of a comprehensive geriatric assessment and comorbidity burden, rather than chronological age...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28031705/earlier-nephrology-consultation-may-not-be-associated-with-improved-short-term-survival-of-acute-kidney-injury-in-very-elderly-men
#3
Qinglin Li, Meng Zhao, Jing Du, Xiaodan Wang
OBJECTIVES: A delayed nephrology consultation (NC) may be associated with a poor prognosis in acute kidney injury (AKI) patients. The aims of this study were to compare the clinical and laboratory characteristics of elderly AKI patients evaluated and not evaluated by nephrologists and to generate a hypothesis regarding the relationship between the timing of the NC and 90-day outcomes. METHODS: From 2007 to 2015, this study explored associations among the presence and timing of NC with the non-intensive care unit stay and 90-day mortality in elderly AKI patients at the Geriatric Department of the Chinese People's Liberation Army General Hospital...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28031704/is-the-acute-care-of-frail-elderly-patients-in-a-comprehensive-geriatric-assessment-unit-superior-to-conventional-acute-medical-care
#4
Niklas Ekerstad, Björn W Karlson, Synneve Dahlin Ivanoff, Sten Landahl, David Andersson, Emelie Heintz, Magnus Husberg, Jenny Alwin
OBJECTIVE: The aim of this study was to investigate whether the acute care of frail elderly patients in a comprehensive geriatric assessment (CGA) unit is superior to the care in a conventional acute medical care unit. DESIGN: This is a clinical, prospective, randomized, controlled, one-center intervention study. SETTING: This study was conducted in a large county hospital in western Sweden. PARTICIPANTS: The study included 408 frail elderly patients, aged ≥75 years, in need of acute in-hospital treatment...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28008242/a-genetic-screen-of-the-mutations-in-the-korean-patients-with-early-onset-alzheimer-s-disease
#5
Seong Soo An, Sun Ah Park, Eva Bagyinszky, Sun Oh Bae, Yoon-Jeong Kim, Ji Young Im, Kyung Won Park, Kee Hyung Park, Eun-Joo Kim, Jee Hyang Jeong, Jong Hun Kim, Hyun Jeong Han, Seong Hye Choi, SangYun Kim
Early-onset Alzheimer's disease (EOAD) has distinct clinical characteristics in comparison to late-onset Alzheimer's disease (LOAD). The genetic contribution is suggested to be more potent in EOAD. However, the frequency of causative mutations in EOAD could be variable depending on studies. Moreover, no mutation screening study has been performed yet employing large population in Korea. Previously, we reported that the rate of family history of dementia in EOAD patients was 18.7% in a nationwide hospital-based cohort study, the Clinical Research Center for Dementia of South Korea (CREDOS) study...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28008241/erratum-prevalence-of-unknown-and-untreated-arrhythmias-in-an-older-outpatient-population-screened-by-wireless-long-term-recording-ecg-corrigendum
#6
(no author information available yet)
[This corrects the article on p. 1083 in vol. 11, PMID: 27570450.].
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28008240/a-comparison-between-metatarsal-head-resurfacing-hemiarthroplasty-and-total-metatarsophalangeal-joint-arthroplasty-as-surgical-treatments-for-hallux-rigidus-a-retrospective-study-with-short-to-midterm-follow-up
#7
Musa Ugur Mermerkaya, Houman Adli
PURPOSE: We evaluated the short- to midterm outcomes of metatarsal head-resurfacing hemiarthroplasty and total metatarsophalangeal joint arthroplasty (total joint replacement [TJR]) as surgical treatments for advanced-stage hallux rigidus (HR). PATIENTS AND METHODS: From 2012 to 2014, all data from patients who underwent surgery for the treatment of grades 2-3 HR were retrospectively reviewed, and 45 patients were included in this study. Of these patients, 26 underwent metatarsal head-resurfacing hemiarthroplasty (Group I) and 19 underwent TJR (Group II)...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28008239/effects-of-different-doses-of-high-speed-resistance-training-on-physical-performance-and-quality-of-life-in-older-women-a-randomized-controlled-trial
#8
Rodrigo Ramirez-Campillo, Daniela Diaz, Cristian Martinez-Salazar, Pablo Valdés-Badilla, Pedro Delgado-Floody, Guillermo Méndez-Rebolledo, Rodrigo Cañas-Jamet, Carlos Cristi-Montero, Antonio García-Hermoso, Carlos Celis-Morales, Jason Moran, Thomas W Buford, Leocadio Rodriguez-Mañas, Alicia M Alonso-Martinez, Mikel Izquierdo
OBJECTIVE: This study aimed to compare the effects of two frequencies of high-speed resistance training (HSRT) on physical performance and quality of life of older women. METHODS: A total of 24 older women participated in a 12-week HSRT program composed of either two or three sessions/week (equated for volume and intensity). Women were randomized into three arms: a control group (CG, n=8), a resistance training group performing two sessions/week (RT2, n=8), and a resistance training group performing three sessions/week (RT3, n=8)...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/27994445/are-older-people-more-vulnerable-to-long-term-impacts-of-disasters
#9
Hassan Rafiey, Yadollah Abolfathi Momtaz, Fardin Alipour, Hamidreza Khankeh, Shokoufeh Ahmadi, Mohammad Sabzi Khoshnami, Sharifah Azizah Haron
BACKGROUND: Despite the growing interest in the study of disasters, there is limited research addressing the elderly population that lead to prejudiced beliefs that older adults are more vulnerable to disasters than younger adults. This study aimed to compare positive mental health between elderly and young earthquake survivors. METHOD: Data for this study, consisting of 324 earthquake survivors, were obtained from a population-based cross-sectional survey conducted in Iran, 2015...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/27994444/the-influence-of-frailty-syndrome-on-medication-adherence-among-elderly-patients-with-hypertension
#10
Beata Jankowska-Polańska, Krzysztof Dudek, Anna Szymanska-Chabowska, Izabella Uchmanowicz
BACKGROUND: Hypertension affects about 80% of people older than 80 years; however, diagnosis and treatment are difficult because about 55% of them do not adhere to treatment recommendations due to low socioeconomic status, comorbidities, age, physical limitations, and frailty syndrome. AIMS: The purposes of this study were to evaluate the influence of frailty on medication adherence among elderly hypertensive patients and to assess whether other factors influence adherence in this group of patients...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/27980398/altered-spontaneous-brain-activity-pattern-in-patients-with-late-monocular-blindness-in-middle-age-using-amplitude-of-low-frequency-fluctuation-a-resting-state-functional-mri-study
#11
Qing Li, Xin Huang, Lei Ye, Rong Wei, Ying Zhang, Yu-Lin Zhong, Nan Jiang, Yi Shao
OBJECTIVE: Previous reports have demonstrated significant brain activity changes in bilateral blindness, whereas brain activity changes in late monocular blindness (MB) at rest are not well studied. Our study aimed to investigate spontaneous brain activity in patients with late middle-aged MB using the amplitude of low-frequency fluctuation (ALFF) method and their relationship with clinical features. METHODS: A total of 32 patients with MB (25 males and 7 females) and 32 healthy control (HC) subjects (25 males and 7 females), similar in age, sex, and education, were recruited for the study...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/27956828/successful-aging-considering-non-biomedical-constructs
#12
REVIEW
Lisa F Carver, Diane Buchanan
OBJECTIVES: Successful aging continues to be applied in a variety of contexts and is defined using a number of different constructs. Although previous reviews highlight the multidimensionality of successful aging, a few have focused exclusively on non-biomedical factors, as was done here. METHODS: This scoping review searched Ovid Medline database for peer-reviewed English-language articles published between 2006 and 2015, offering a model of successful aging and involving research with older adults...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/27956827/efficacy-and-safety-of-prostate-artery-embolization-on-lower-urinary-tract-symptoms-related-to-benign-prostatic-hyperplasia-a-systematic-review-and-meta-analysis
#13
Xiao-Yan Wang, Huan-Tao Zong, Yong Zhang
BACKGROUND: Prostate artery embolization (PAE) is emerging and is a promising minimally invasive therapy that improves lower urinary tract symptoms (LUTS) related to benign prostatic hyperplasia (BPH). The purpose of this article was to evaluate the efficacy and safety of PAE on LUTS related to BPH. MATERIALS AND METHODS: A literature review was performed to identify all published articles of PAE for BPH. The sources included MEDLINE, EMBASE and Cochrane Library from 1980 to 2016...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/27956826/nonmotor-gastrointestinal-disorders-in-older-patients-with-parkinson-s-disease-is-there-hope
#14
Doina Georgescu, Oana Elena Ancusa, Liviu Andrei Georgescu, Ioana Ionita, Daniela Reisz
Despite the fact that nonmotor symptoms (NMS) like gastrointestinal (GI) complaints are frequently reported in Parkinson's disease (PD), no therapeutic guidelines are available. This study aimed to manage some lower GI-NMS in a group of patients with PD. A total of 40 patients (17 males, 23 females; mean age 76.05±2.09 years) were randomly selected for this study. Patients were confirmed to have PD (modified Hoehn-Yars scale: 2.075±0.4) who had undergone levodopa or dopamine agonist treatment. In the non-motor symptoms questionnaire (NMS-Quest), regarding GI complaints, the following were recorded: abdominal pain, bloating, and constipation of mild-to-moderate severity...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/27942207/effects-of-short-term-nordic-walking-training-on-sarcopenia-related-parameters-in-women-with-low-bone-mass-a-preliminary-study
#15
Zbigniew Marcin Ossowski, Wojciech Skrobot, Piotr Aschenbrenner, Vida Janina Cesnaitiene, Mirosław Smaruj
BACKGROUND: Several studies have demonstrated the positive effects of physical activity on skeletal muscle mass and muscle strength in women with osteoporosis. However, the impact of Nordic walking training on sarcopenia-related parameters in women with low bone mass remains unknown. Therefore, the purpose of this study was to evaluate the impact of 12 weeks of Nordic walking training on skeletal muscle index, muscle strength, functional mobility, and functional performance in women with low bone mass...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/27942206/carers-education-improves-oral-health-of-older-people-suffering-from-dementia-results-of-an-intervention-study
#16
Andreas Zenthöfer, Inga Meyer-Kühling, Anna-Luisa Hufeland, Johannes Schröder, Tomas Cabrera, Dominik Baumgart, Peter Rammelsberg, Alexander J Hassel
AIM: The aim of this study was to evaluate the effectiveness of carers' education on improvements in oral health and denture hygiene of care-dependent and cognitively impaired older people in nursing homes compared to those without intervention. METHODS: A total of 219 seniors living in 14 nursing homes in southwest Germany (intervention: n=144; control: n=75) were enrolled in this study. For each participant, Plaque Control Record (PCR), Gingival Bleeding Index (GBI), Denture Hygiene Index (DHI) and Community Periodontal Index of Treatment Needs (CPITN) were assessed at baseline and six months following the interventions...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/27932871/efficacy-and-safety-outcomes-of-fractional-flow-reserve-in-guiding-clinical-therapy-of-non-st-segment-elevation-myocardial-infarction-compared-with-angiography-alone-in-elderly-chinese-patients
#17
Zhao Zhang, Ke Li, Jinwen Tian
OBJECTIVE: Fractional flow reserve (FFR) is an innovative method for evaluating the physiological significance of a coronary stenosis, but its validity is less certain in patients with non-ST-segment elevation myocardial infarction (NSTEMI). It is important to assess whether FFR is effective and safe in patients, especially elderly Chinese patients, with NSTEMI. As the first one in China, the purpose of this study was to establish the efficacy and safety outcomes of FFR in guiding clinical therapy of NSTEMI compared with angiography alone in elderly Chinese patients...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/27932870/evaluation-of-quality-of-life-in-chronic-progressing-rheumatic-diseases-based-on-the-example-of-osteoarthritis-and-rheumatoid-arthritis
#18
Izabela Wysocka-Skurska, Matylda Sierakowska, Wojciech Kułak
BACKGROUND: Rheumatic diseases, irrespective of etiology and clinical course, influence different areas of a patient's life. Adapting to disability and limitations caused by an illness is very difficult for many patients. The main goal of a therapeutic procedure should be improvement of health-related quality of life (QoL). OBJECTIVE: Evaluation of the factors that influence the QoL that are conditioned by the state of health of patients with osteoarthritis (OA) and rheumatoid arthritis (RA)...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/27932869/person-centered-dementia-care-current-perspectives
#19
REVIEW
Jill Manthorpe, Kritika Samsi
Person-centered dementia care is widely accepted as a value-based commitment to supporting people with dementia and is a guiding principle in care services. Policy ambitions to put people at the center of their own care are being developed internationally. These may be seen as part of the evolution of person-centered care which has its origins in critical perspectives on practice and social responses to people with dementia. In England, one further development of person-centered care has been personalization - a government policy to extend individuals' choice and control over their social care and, latterly, ways to meet their health care needs...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/27920511/relationships-between-fto-rs9939609-mc4r-rs17782313-and-ppar%C3%AE-rs1801282-polymorphisms-and-the-occurrence-of-selected-metabolic-and-hormonal-disorders-in-middle-aged-and-elderly-men-a-preliminary-study
#20
Iwona Rotter, Karolina Skonieczna-Żydecka, Danuta Kosik-Bogacka, Grażyna Adler, Aleksandra Rył, Maria Laszczyńska
PURPOSE: Metabolic disorders, including MetS, obesity, and lipid disorders, may be related to genetic factors. Metabolic disorders are associated with decreased TS levels in aging men. The aim of this study was to evaluate the relationship between FTO rs9939609, MC4R rs17782313, and PPARγ rs1801282 polymorphisms and the presence of MetS and its components, the concurrent lipid disorders, as well as sex hormone concentrations. SUBJECTS AND METHODS: This study involved 272 men of Caucasian descent aged 50-75 years...
2016: Clinical Interventions in Aging
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