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Clinical Interventions in Aging

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https://www.readbyqxmd.com/read/28496313/relationships-of-pancreatic-beta-cell-function-with-microalbuminuria-and-glomerular-filtration-rate-in-middle-aged-and-elderly-population-without-type-2-diabetes-mellitus-a-chinese-community-based-analysis
#1
Shihui Fu, Shanjing Zhou, Leiming Luo, Ping Ye
BACKGROUND: Relationships of pancreatic beta-cell function abnormality with microalbuminuria (MA) and glomerular filtration rate (GFR) may differ by age, ethnicity and accompanied diseases. Previous studies were generally conducted in Western adult patients with type 2 diabetes mellitus (T2DM), and it is uncertain whether pancreatic beta-cell function is associated with MA and GFR in Chinese community-dwelling middle-aged and elderly population without T2DM. We therefore examined the relationships of pancreatic beta-cell function with two indices of renal damage, MA and GFR, in Chinese community-dwelling middle-aged and elderly population without T2DM...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28496312/body-mass-index-is-associated-with-type-2-diabetes-mellitus-in-chinese-elderly
#2
Qianping Zhao, Jari A Laukkanen, Qifu Li, Gang Li
BACKGROUND: There is limited information on the association between metabolic syndrome components including body mass index (BMI) and type 2 diabetes mellitus in elderly Chinese population. Therefore, we investigated whether components of metabolic syndrome are associated with type 2 diabetes mellitus in elderly. METHODS: A total of 479 hospitalized patients (aged 65-95 years) with recently diagnosed type 2 diabetes mellitus were studied retrospectively in a cross-sectional study and compared with 183 subjects with prediabetes and 62 subjects without glucose metabolism abnormalities...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28496311/letter-regarding-the-article-the-impact-of-hypomagnesemia-on-erectile-dysfunction-in-elderly-non-diabetic-stage-3-and-4-chronic-kidney-disease-patients-a-prospective-cross-sectional-study
#3
COMMENT
Pasquale Fatuzzo, Luca Zanoli, Viviana Scollo
No abstract text is available yet for this article.
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28490866/nonpharmacological-interventions-to-treat-physical-frailty-and-sarcopenia-in-older-patients-a-systematic-overview-the-senator-project-ontop-series
#4
REVIEW
Isabel Lozano-Montoya, Andrea Correa-Pérez, Iosief Abraha, Roy L Soiza, Antonio Cherubini, Denis O'Mahony, Alfonso J Cruz-Jentoft
BACKGROUND: Physical frailty (PF) and sarcopenia are predictors of negative health outcomes such as falls, disability, hospitalization, and death. Some systematic reviews (SRs) have been published on different nonpharmacological treatments of frailty and sarcopenia using heterogeneous definitions of them. OBJECTIVE: To critically appraise the evidence from SRs of the primary studies on nonpharmacological interventions to treat PF (defined by Fried's frailty phenotype) and sarcopenia (defined by the EWGSOP) in older patients...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28461745/depression-and-chronic-pain-in-the-elderly-links-and-management-challenges
#5
REVIEW
Panagiotis Zis, Argyro Daskalaki, Ilia Bountouni, Panagiota Sykioti, Giustino Varrassi, Antonella Paladini
Aging is an inevitable process and represents the accumulation of bodily alterations over time. Depression and chronic pain are highly prevalent in elderly populations. It is estimated that 13% of the elderly population will suffer simultaneously from the two conditions. Accumulating evidence suggests than neuroinflammation plays a critical role in the pathogenesis of both depression and chronic pain. Apart from the common pathophysiological mechanisms, however, the two entities have several clinical links...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28458525/rivastigmine-the-advantages-of-dual-inhibition-of-acetylcholinesterase-and-butyrylcholinesterase-and-its-role-in-subcortical-vascular-dementia-and-parkinson-s-disease-dementia
#6
REVIEW
Nagaendran Kandiah, Ming-Chyi Pai, Vorapun Senanarong, Irene Looi, Encarnita Ampil, Kyung Won Park, Ananda Krishna Karanam, Stephen Christopher
Several studies have demonstrated clinical benefits of sustained cholinesterase inhibition with rivastigmine in Alzheimer's disease (AD) and Parkinson's disease dementia (PDD). Unlike donepezil and galantamine that selectively inhibit acetylcholinesterase (AChE; EC 3.1.1.7), rivastigmine is a unique cholinesterase inhibitor with both AChE and butyrylcholinesterase (BuChE; EC 3.1.1.8) inhibitory activity. Rivastigmine is also available as transdermal patch that has been approved by the US Food and Drug Administration for the treatment of mild, moderate, and severe AD as well as mild-to-moderate PDD...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28450779/clinical-differences-among-the-elderly-admitted-to-the-emergency-department-for-accidental-or-unexplained-falls-and-syncope
#7
Giuseppe Pasqualetti, Valeria Calsolaro, Giacomo Bini, Umberto Dell'Agnello, Marco Tuccori, Alessandra Marino, Alice Capogrosso-Sansone, Martina Rafanelli, Massimo Santini, Eugenio Orsitto, Andrea Ungar, Corrado Blandizzi, Fabio Monzani
It is difficult to distinguish unexplained falls (UFs) from accidental falls (AFs) or syncope in older people. This study was designed to compare patients referred to the emergency department (ED) for AFs, UFs or syncope. Data from a longitudinal study on adverse drug events diagnosed at the ED (ANCESTRAL-ED) in older people were analyzed in order to select cases of AF, syncope, or UF. A total of 724 patients (median age: 81.0 [65-105] years, 66.3% female) were consecutively admitted to the ED (403 AF, 210 syncope, and 111 UF)...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28442898/medication-regimen-complexity-in-ambulatory-older-adults-with-heart-failure
#8
Michael R Cobretti, Robert L Page, Sunny A Linnebur, Kimberly M Deininger, Amrut V Ambardekar, JoAnn Lindenfeld, Christina L Aquilante
PURPOSE: Heart failure prevalence is increasing in older adults, and polypharmacy is a major problem in this population. We compared medication regimen complexity using the validated patient-level Medication Regimen Complexity Index (pMRCI) tool in "young-old" (60-74 years) versus "old-old" (75-89 years) patients with heart failure. We also compared pMRCI between patients with ischemic cardiomyopathy (ISCM) versus nonischemic cardiomyopathy (NISCM). PATIENTS AND METHODS: Medication lists were retrospectively abstracted from the electronic medical records of ambulatory patients aged 60-89 years with heart failure...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28442897/cost-effectiveness-analysis-of-oral-versus-intravenous-drip-infusion-of-levofloxacin-in-the-treatment-of-acute-lower-respiratory-tract-infection-in-chinese-elderly-patients
#9
Libin Zhang, Ping Hu
AIM: Pharmacoeconomic cost-effectiveness analysis of two different dosage regimens of levofloxacin in the treatment of acute lower respiratory tract infection in elderly patients. METHODS: A total of 108 elderly patients with acute lower respiratory tract infection who visited by our hospital between September 2013 and September 2014 were randomly divided into Group A and Group B, with 54 patients in each group. In Group A, levofloxacin injection was given for continuous intravenous infusion treatment, whereas in Group B, levofloxacin injection and levofloxacin capsule were given as sequential therapy (ST)...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28442896/comparison-of-safety-and-outcomes-of-shock-wave-lithotripsy-between-elderly-and-non-elderly-patients
#10
Yi-Zhong Chen, Wun-Rong Lin, Chih-Chiao Lee, Fang-Ju Sun, Yung-Chiong Chow, Wei-Kung Tsai, Pai-Kai Chiang, Ting-Po Lin, Marcelo Chen, Allen W Chiu
BACKGROUND: This study compared the clinical outcomes of extracorporeal shock wave lithotripsy between elderly (aged $65 years) and non-elderly (aged <65 years) patients. METHODS: A retrospective review of medical records was performed on 483 (non-elderly: 245, elderly: 238) patients with upper urinary tract stones who underwent shock wave lithotripsy between 2007 and 2015. The demographic data, stone parameters, stone-free rate, retreatment rate, and complication rate were analyzed in both elderly and non-elderly patient groups...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28442895/oral-health-related-quality-of-life-and-prosthetic-status-of-nursing-home-residents-with-or-without-dementia
#11
Anna-Luisa Klotz, Alexander Jochen Hassel, Johannes Schröder, Peter Rammelsberg, Andreas Zenthöfer
PURPOSE: The objective of this cross-sectional study was to evaluate the effect of prosthetic status on the oral health-related quality of life (OHRQoL) of nursing home residents with or without dementia. METHODS: The study was performed in 14 nursing homes across the federal state of Baden-Württemberg, Germany. All eligible participants were included, and general and medical information and information about their dental and prosthetic statuses were collected...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28435237/evaluation-of-ex-press-glaucoma-implant-in-elderly-diabetic-patients-after-23g-vitrectomy
#12
Anita Lyssek-Boroń, Adam Wylęgała, Dariusz Dobrowolski, Ewelina Kowalczyk, Katarzyna Polanowska, Edward Wylęgała
PURPOSE: The most frequent qualifications for pars plana vitrectomy (PPV) in diabetic patients include recurrent hemorrhage into the vitreous body chamber and vitreoretinal proliferation, also with traction retinal detachment. The aim of this study was to evaluate the effectiveness of EX-PRESS implant for the treatment of secondary glaucoma in elderly diabetic patients following PPV 23G with silicon oil or SF6 gas endotamponade. MATERIALS AND METHODS: This retrospective analysis comprised 18 patients (19 eyes)...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28435236/activities-specific-balance-confidence-scale-for-predicting-future-falls-in-indian-older-adults
#13
Jamal Ali Moiz, Vishal Bansal, Majumi M Noohu, Shailendra Nath Gaur, Mohammad Ejaz Hussain, Shahnawaz Anwer, Ahmad Alghadir
BACKGROUND: Activities-specific balance confidence (ABC) scale is a subjective measure of confidence in performing various ambulatory activities without falling or experiencing a sense of unsteadiness. OBJECTIVE: This study aimed to examine the ability of the Hindi version of the ABC scale (ABC-H scale) to discriminate between fallers and non-fallers and to examine its predictive validity for prospective falls. DESIGN: This was a prospective cohort study...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28435235/age-based-model-for-metacarpophalangeal-joint-proprioception-in-elderly
#14
Mike D Rinderknecht, Olivier Lambercy, Vanessa Raible, Joachim Liepert, Roger Gassert
Neurological injuries such as stroke can lead to proprioceptive impairment. For an informed diagnosis, prognosis, and treatment planning, it is essential to be able to distinguish between healthy performance and deficits following the neurological injury. Since there is some evidence that proprioception declines with age and stroke occurs predominantly in the elderly population, it is important to create a healthy reference model in this specific age group. However, most studies investigate age effects by comparing young and elderly subjects and do not provide a model within a target age range...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28424547/omega-3-fatty-acid-supplementation-can-improve-both-symptoms-and-signs-of-dry-eye-disease
#15
COMMENT
Jae-Woo Kwon, Sang Beom Han
No abstract text is available yet for this article.
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28424546/perspectives-of-older-people-living-in-long-term-care-facilities-and-of-their-family-members-toward-advance-care-planning-discussions-a-systematic-review-and-thematic-synthesis
#16
REVIEW
Veronica Mignani, Francesca Ingravallo, Elena Mariani, Rabih Chattat
OBJECTIVE: We aimed to search and synthesize qualitative studies exploring the perspectives of older people living in long-term care facilities and of their family members about advance care planning (ACP) discussions. METHODS: The enhancing transparency in reporting the synthesis of qualitative research (ENTREQ) framework was used to guide the review and report its results. PubMed, CINAHL, and PsycINFO were searched for studies published between January 2000 and November 2015...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28424545/efficacy-and-safety-of-alcohol-septal-ablation-in-patients-over-65-years-old-with-obstructive-hypertrophic-cardiomyopathy
#17
Laila Cheddadi, Olivier Lairez, Thibault Lhermusier, Francisco Campelo-Parada, Michel Galinier, Didier Carrié, Nicolas Boudou
BACKGROUND: The performance of alcohol septal ablation (ASA) in elderly symptomatic patients with drug-refractory obstructive hypertrophic cardiomyopathy is still to be confirmed. The objective of this study was to compare the efficacy and safety of ASA in patients under and over 65 years old. METHODS AND RESULTS: Fifty-one consecutive patients with obstructive hypertrophic cardio-myopathy who underwent ASA were retrospectively included and reviewed for in-hospital major acute cardiac events and follow-up...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28424544/association-of-genetic-variations-in-the-mitochondrial-dna-control-region-with-presbycusis
#18
Masoumeh Falah, Mohammad Farhadi, Seyed Kamran Kamrava, Saeid Mahmoudian, Ahmad Daneshi, Maryam Balali, Alimohamad Asghari, Massoud Houshmand
BACKGROUND: The prominent role of mitochondria in the generation of reactive oxygen species, cell death, and energy production contributes to the importance of this organelle in the intracellular mechanism underlying the progression of the common sensory disorder of the elderly, presbycusis. Reduced mitochondrial DNA (mtDNA) gene expression and coding region variation have frequently been reported as being associated with the development of presbycusis. The mtDNA control region regulates gene expression and replication of the genome of this organelle...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28408812/relationship-between-jaw-opening-force-and-hyoid-bone-dynamics-in-healthy-elderly-subjects
#19
Hiromichi Shinozaki, Haruka Tohara, Mariko Matsubara, Nobuhiro Inokuchi, Yasuhiro Yamazaki, Ayako Nakane, Yoko Wakasugi, Shunsuke Minakuchi
PURPOSE: This study aimed to examine the relationship between jaw opening force and hyoid bone dynamics and resting position in elderly individuals based on gender. SUBJECTS AND METHODS: Subjects were 36 healthy elderly individuals aged ≥65 years without dysphagia (16 men and 20 women; mean age 75.5 years, range 65-88 years). Videofluorographic images during the swallowing of 10 mL of 40% (w/v) barium sulfate were obtained and the degrees of anterior, superior, and hypotenuse displacements of the hyoid bone and maximum/resting hyoid position were evaluated...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28408811/systematic-review-on-strength-training-in-parkinson-s-disease-an-unsolved-question
#20
REVIEW
Ileana Ramazzina, Benedetta Bernazzoli, Cosimo Costantino
The purpose of this study was to investigate the effectiveness of strength training, performed against a different resistance from body weight, in improving motor and nonmotor symptoms in patients with Parkinson's disease (PD). The following electronic databases were searched: PubMed, Physiotherapy Evidence Database, Cochrane Central Register of Controlled Trials, Scopus, and Web of Science. The review was conducted and reported in accordance with the PRISMA statement. Thirteen high-quality randomized controlled trials were included...
2017: Clinical Interventions in Aging
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