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Vascular Health and Risk Management

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https://www.readbyqxmd.com/read/29928127/isolated-proximal-greater-saphenous-vein-thrombosis-and-the-risk-of-propagation-to-deep-vein-thrombosis-and-pulmonary-embolism
#1
Samuel H Kim, Nimesh Patel, Kanika Thapar, Ananda V Pandurangadu, Amit Bahl
Objectives: Greater saphenous vein (GSV) thrombosis is concerning due to its close proximity to the deep femoral vein. This study sought to identify the risk of propagation to deep vein thrombosis (DVT) or pulmonary embolism (PE) among patients with isolated proximal GSV superficial thrombosis and describe provider practice patterns related to treatment. Materials and methods: This is an Institutional Review Board-approved retrospective multi-center study. Patients presented to one of three possible emergency departments in a large health system...
2018: Vascular Health and Risk Management
https://www.readbyqxmd.com/read/29928126/the-association-between-the-serum-level-of-vitamin-d-and-ischemic-heart-disease-a-study-from-jordan
#2
Mohamad I Jarrah, Nizar M Mhaidat, Karem H Alzoubi, Nasr Alrabadi, Enas Alsatari, Yousef Khader, Moath F Bataineh
Background: Decreased levels of vitamin D were associated with increased risk of multiple diseases, including cardiovascular diseases. However, there seem to be some discrepancies among the results obtained from different studies. The aim of the present study was to explore the importance of having sufficient serum levels of vitamin D in reducing the incidence and the progression of coronary artery stenosis and ischemic heart disease (IHD). Methods: Serum levels of vitamin D were measured using radioimmunoassay in 186 Jordanian patients who underwent investigative coronary catheterization...
2018: Vascular Health and Risk Management
https://www.readbyqxmd.com/read/29881284/anemia-and-acute-coronary-syndrome-current-perspectives
#3
REVIEW
Miriam Stucchi, Silvia Cantoni, Enrico Piccinelli, Stefano Savonitto, Nuccia Morici
Reference hemoglobin (Hb) values for the definition of anemia are still largely based on the 1968 WHO Scientific Group report, which established a cutoff value of <13 g/dL for adult men and <12 g/dL for adult nonpregnant women. Subsequent studies identified different normal values according to race and age. Estimated prevalence of anemia on admission in the setting of an acute coronary syndrome (ACS) is between 10% and 43% of the patients depending upon the specific population under investigation. Furthermore, up to 57% of ACS patients may develop hospital-acquired anemia (HAA)...
2018: Vascular Health and Risk Management
https://www.readbyqxmd.com/read/29881283/expression-of-phospholipase-a2-receptor-and-igg4-in-patients-with-membranous-nephropathy
#4
Lei Liu, Baochao Chang, Xueping Wu, Yaling Guo, Yan Pan, Lijuan Yang
Objectives: The aims of this study were to detect the expression of M phospholipase A2 receptor (PLA2R) in the kidney tissue of patients with idiopathic membranous nephropathy (IMN), secondary membranous nephropathy (SMN), and the nonmembranous nephropathy (non-MN), to evaluate the value of PLA2R in the kidney tissue and serum anti-PLA2R antibody in the diagnosis of membranous nephropathy (MN), and to explore the relationship between PLA2R of the kidney tissue or serum anti-PLA2R antibody and clinical features of MN...
2018: Vascular Health and Risk Management
https://www.readbyqxmd.com/read/29872306/nonadherence-to-statins-individualized-intervention-strategies-outside-the-pill-box
#5
REVIEW
Peter Lansberg, Andre Lee, Zhen-Vin Lee, Kannan Subramaniam, Sajita Setia
Poor adherence to statin therapy is linked to significantly increased risk of cardiovascular events and death. Unfortunately, adherence to statins is far from optimal. This is an alarming concern for patients prescribed potentially life-saving cholesterol-lowering medication, especially for those at high risk of cardiovascular events. Research on statin adherence has only recently garnered broader attention; hence, major reasons unique to adherence to statin therapy need to be identified as well as suggestions for countermeasures...
2018: Vascular Health and Risk Management
https://www.readbyqxmd.com/read/29780248/incidence-of-symptomatic-venous-thromboembolism-in-2372-knee-and-hip-replacement-patients-after-discharge-data-from-a-thromboprophylaxis-registry-in-montreal-canada
#6
Andréa Senay, Milanne Trottier, Josée Delisle, Andreea Banica, Benoit Benoit, G Yves Laflamme, Michel Malo, Hai Nguyen, Pierre Ranger, Julio C Fernandes
Background: Low-molecular-weight heparin (LMWH) is a recommended anticoagulant for thromboprophylaxis after major orthopedic surgery. Dabigatran etexilate is an oral anticoagulant recognized as noninferior to LMWH. We aimed to assess the incidence of symptomatic venous thromboembolic events (VTEs) after discharge in patients who underwent joint replacement, using a hospital registry. Patients and methods: Patients who underwent total knee and hip arthroplasty between September 2011 and March 2015 were selected...
2018: Vascular Health and Risk Management
https://www.readbyqxmd.com/read/29765227/age-gender-distribution-of-coronary-artery-calcium-score-in-a-black-african-population-in-ghana
#7
George Asafu Adjaye Frimpong, Isaac Kofi Owusu, Ijeoma Chinedum Anyitey-Kokor, Caitlin Selassie Naa Sarku Wiafe-Kwakye, Evans Aboagye, Nana Esi Coleman, Pierre Amankwah, Nakao Kuukua Abaidoo
Background: Distribution of coronary artery calcium (CAC) has been determined in different heterogeneous populations in the Multi-Ethnic Study of Atherosclerosis (MESA). Based on findings showing that geography and culture can influence CAC scoring beyond traditional race groups, we determined the distribution of CAC in a homogenous black African population to provide an initial basis for a larger CAC score study in Africa. Methods and results: This is a preliminary study using computed tomography to determine the CAC scores within a black African population who were referred to our center...
2018: Vascular Health and Risk Management
https://www.readbyqxmd.com/read/29731636/critical-limb-ischemia-current-challenges-and-future-prospects
#8
REVIEW
Luigi Uccioli, Marco Meloni, Valentina Izzo, Laura Giurato, Stefano Merolla, Roberto Gandini
Critical limb ischemia (CLI) is considered the most severe pattern of peripheral artery disease. It is defined by the presence of chronic ischemic rest pain, ulceration or gangrene attributable to the occlusion of peripheral arterial vessels. It is associated with a high risk of major amputation, cardiovascular events and death. In this review, we presented a complete overview about physiopathology, diagnosis and holistic management of CLI. Revascularization is the first-line treatment, but several challenging cases are not treatable by conventional techniques...
2018: Vascular Health and Risk Management
https://www.readbyqxmd.com/read/29662315/pitfalls-in-the-ankle-brachial-index-and-brachial-ankle-pulse-wave-velocity
#9
Dai Ato
Background: The ankle-brachial index (ABI) and pulse wave velocity (PWV) are indices of atherosclerosis and arterial stiffness. The Japan-made measuring devices of those indices have spread widely because of their convenience and the significance of the parameters. However, studies that comprehensively discuss the various pitfalls in using these indices are not available. Methods: This study presents several representative pitfalls in using the ABI and brachial-ankle PWV (baPWV) by showing the result sheets of the device, "the Vascular Profiler"...
2018: Vascular Health and Risk Management
https://www.readbyqxmd.com/read/29445287/patient-knowledge-on-stroke-risk-factors-symptoms-and-treatment-options
#10
Kashif Waqar Faiz, Antje Sundseth, Bente Thommessen, Ole Morten Rønning
Background: Public campaigns focus primarily on stroke symptom and risk factor knowledge, but patients who correctly recognize stroke symptoms do not necessarily know the reason for urgent hospitalization. The aim of this study was to explore knowledge on stroke risk factors, symptoms and treatment options among acute stroke and transient ischemic attack patients. Methods: This prospective study included patients admitted to the stroke unit at the Department of Neurology, Akershus University Hospital, Norway...
2018: Vascular Health and Risk Management
https://www.readbyqxmd.com/read/29440909/clinical-characteristics-patterns-of-lipid-lowering-medication-use-and-health-care-resource-utilization-and-costs-among-patients-with-atherosclerotic-cardiovascular-disease
#11
Thomas P Power, Xuehua Ke, Zhenxiang Zhao, Nicole Gidaya Bonine, Mark J Cziraky, Michael Grabner, John J Barron, Ralph Quimbo, Burkhard Vangerow, Peter P Toth
Purpose: The aim of this study was to investigate real-world patient characteristics, medication use, and health care resource utilization (HCRU) and costs among patients with clinical atherosclerotic cardiovascular disease (ASCVD) as defined by 2013 American College of Cardiology/American Heart Association (ACC/AHA) guidelines, to examine burden of disease and unmet needs, such as potential undertreatment. Patients and methods: This retrospective cohort study utilized a nationally representative managed care database to identify newly diagnosed ASCVD patients between January 1, 2007, and November 30, 2012 (index = first ASCVD diagnosis date) in the USA...
2018: Vascular Health and Risk Management
https://www.readbyqxmd.com/read/29391805/role-of-rivaroxaban-in-the-management-of-atrial-fibrillation-insights-from-clinical-practice
#12
REVIEW
Kavitha Vimalesvaran, Seth J Dockrill, Diana A Gorog
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, and it leads to significant morbidity and mortality, predominantly from ischemic stroke. Vitamin K antagonists, mainly warfarin, have been used for decades to prevent ischemic stroke in AF, but their use is limited due to interactions with food and other drugs, as well as the requirement for regular monitoring of the international normalized ratio. Rivaroxaban, a direct factor Xa inhibitor and the most commonly used non-vitamin K oral anticoagulant, avoids many of these challenges and is being prescribed with increasing frequency for stroke prevention in non-valvular AF...
2018: Vascular Health and Risk Management
https://www.readbyqxmd.com/read/29343965/postural-tachycardia-syndrome-current-perspectives
#13
REVIEW
Rachel Wells, Andrew J Spurrier, Dominik Linz, Celine Gallagher, Rajiv Mahajan, Prashanthan Sanders, Amanda Page, Dennis H Lau
Postural tachycardia syndrome (POTS) is the combination of an exaggerated heart rate response to standing, in association with symptoms of lightheadedness or pre-syncope that improve when recumbent. The condition is often associated with fatigue and brain fog, resulting in significant disruptions at a critical time of diagnosis in adolescence and young adulthood. The heterogeneity of the underlying pathophysiology and the variable response to therapeutic interventions make management of this condition challenging for both patients and physicians alike...
2018: Vascular Health and Risk Management
https://www.readbyqxmd.com/read/29270016/extracorporeal-ultrafiltration-for-acute-heart-failure-patient-selection-and-perspectives
#14
REVIEW
Valentina Milazzo, Nicola Cosentino, Giancarlo Marenzi
Most patients presenting with acute heart failure (AHF) show signs and symptoms of fluid overload, which are closely associated with short-term and long-term outcomes. Ultrafiltration is an extremely appealing strategy for patients with AHF and concomitant overt fluid overload not fully responsive to diuretic therapy. However, although there are several theoretical beneficial effects associated with ultrafiltration, published reports have shown controversial findings. Differences in selection of the study population and in ultrafiltration indications and protocols, and high variability in the pharmacologic therapy used for the control group could explain some of these conflicting results...
2017: Vascular Health and Risk Management
https://www.readbyqxmd.com/read/29263674/practical-guidance-on-the-use-of-laboratory-testing-in-the-management-of-bleeding-in-patients-receiving-direct-oral-anticoagulants
#15
REVIEW
Hugo Ten Cate, Yvonne Mc Henskens, Marcus D Lancé
Direct oral anticoagulants (DOACs) have demonstrated a favorable benefit-risk profile in several thromboembolic disorders and are increasingly used in routine clinical practice. A number of real-world studies on DOACs are ongoing, and data published so far have shown broadly similar outcomes to those demonstrated in the respective phase III trials. Despite their beneficial attributes, bleeding risk (as with any other anticoagulants) is often a concern for physicians when prescribing DOACs, particularly in elderly patients, those with significant comorbidities, and other high-risk patient populations...
2017: Vascular Health and Risk Management
https://www.readbyqxmd.com/read/29225469/pelvic-vein-incompetence-clinical-perspectives
#16
REVIEW
David M Riding, Vivak Hansrani, Charles McCollum
Chronic pelvic pain (CPP) affects 24% of premenopausal women, accounts for 20%-30% of UK gynecology outpatient appointments, and has an annual pan-European economic cost of €3.8 billion. Despite extensive investigation, often including laparoscopy, up to 55% of women do not receive a diagnosis and endure persistent symptoms. In these patients, clinical management focuses on symptom control rather than treatment. It is possible that pelvic vein incompetence (PVI) is a cause of CPP, although the quality of studies investigating an association is generally low...
2017: Vascular Health and Risk Management
https://www.readbyqxmd.com/read/29200864/efficacy-of-noninvasive-cardiac-imaging-tests-in-diagnosis-and-management-of-stable-coronary-artery-disease
#17
REVIEW
Ify R Mordi, Athar A Badar, R John Irving, Jonathan R Weir-McCall, J Graeme Houston, Chim C Lang
The aim of this review was to discuss the current literature regarding the utility of noninvasive imaging in diagnosis and management of stable coronary artery disease (CAD) including recent data from large randomized trials assessing diagnosis and prognosis. Current guidelines recommend revascularization in patients with refractory angina and in those with potential prognostic benefit. Appropriate risk stratification through noninvasive assessment is important in ensuring patients are not exposed to unnecessary invasive coronary angiograms...
2017: Vascular Health and Risk Management
https://www.readbyqxmd.com/read/29200863/endothelial-dysfunction-assessment-by-flow-mediated-dilation-in-a-high-altitude-population
#18
Walter S Calderón-Gerstein, Antonio López-Peña, Raúl Macha-Ramírez, Astrid Bruno-Huamán, Roxana Espejo-Ramos, Stephany Vílchez-Bravo, María Ramírez-Breña, Milagros Damián-Mucha, Adriana Matos-Mucha
Introduction: Endothelial function at high altitude has been measured only in populations that are genetically adapted to chronic hypoxia. The objective of this study was to evaluate endothelial dysfunction (ED) in a nongenetically adapted high-altitude population of the Andes mountains, in Huancayo, Peru (3,250 meters above sea level). Methods: Participants included 61 patients: 28 cases and 33 controls. The cases were subjects with hypertension, diabetes mellitus, obesity, or a history of stroke or coronary artery disease...
2017: Vascular Health and Risk Management
https://www.readbyqxmd.com/read/29158679/treatment-of-pulmonary-hypertension-with-left-heart-disease-a-concise-review
#19
REVIEW
Anish Desai, Shilpa A Desouza
Pulmonary hypertension (PH) is defined by a mean pulmonary artery pressure ≥ 25 mmHg, as determined by right heart catheterization. Pulmonary arterial hypertension (PAH) can no longer be considered an orphan disease given the increase in awareness and availability of new drugs. PH carries with it a dismal prognosis and leads to significant morbidity and mortality. Symptoms can range from dyspnea, fatigue and chest pain to right ventricular failure and death. PH is divided into five groups by the World Health Organization (WHO), based on etiology...
2017: Vascular Health and Risk Management
https://www.readbyqxmd.com/read/29138570/erratum-quick-reference-guide-to-apixaban-corrigendum
#20
(no author information available yet)
[This corrects the article on p. 263 in vol. 13, PMID: 28744136.].
2017: Vascular Health and Risk Management
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