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Clinical Journal of the American Society of Nephrology: CJASN

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https://www.readbyqxmd.com/read/28811297/patterns-of-nsaids-use-and-their-association-with-other-analgesic-use-in-ckd
#1
Min Zhan, Wendy L St Peter, Rebecca M Doerfler, Corinne M Woods, Jacob B Blumenthal, Clarissa J Diamantidis, Chi-Yuan Hsu, James P Lash, Eva Lustigova, Erin B Mahone, Akinlolu O Ojo, Anne Slaven, Louise Strauss, Jonathan J Taliercio, Wolfgang C Winkelmayer, Dawei Xie, Jeffery C Fink
BACKGROUND AND OBJECTIVES: Avoiding nonsteroidal anti-inflammatory drugs is important for safe CKD care. This study examined nonsteroidal anti-inflammatory drug use patterns and their association with other analgesic use in CKD. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: The Chronic Renal Insufficiency Cohort Study is an observational cohort study that enrolled 3939 adults ages 21-74 years old with CKD between 2003 and 2008 using age-based eGFR inclusion criteria...
August 15, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28801528/epidemiology-and-natural-history-of-the-cardiorenal-syndromes-in-a-cohort-with-echocardiography
#2
Thomas A Mavrakanas, Aisha Khattak, Karandeep Singh, David M Charytan
BACKGROUND AND OBJECTIVES: It is unknown whether echocardiographic parameters are independently associated with the cardiorenal syndrome. No direct comparison of the natural history of various cardiorenal syndrome types has been conducted. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Our retrospective cohort study enrolled adult patients with at least one transthoracic echocardiography between 2004 and 2014 at a single health care system. Information on comorbidities was extracted using condition-specific diagnostic codes...
August 11, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28801527/circulating-antibodies-against-thrombospondin-type-i-domain-containing-7a-in-chinese-patients-with-idiopathic-membranous-nephropathy
#3
Jia Wang, Zhao Cui, Jie Lu, Christian Probst, Yi-Miao Zhang, Xin Wang, Zhen Qu, Fang Wang, Li-Qiang Meng, Xu-Yang Cheng, Gang Liu, Hanna Debiec, Pierre Ronco, Ming-Hui Zhao
BACKGROUND AND OBJECTIVES: Thrombospondin type-I domain-containing 7A (THSD7A) was recently identified as the target antigen in about 10% of patients with M-type phospholipase A2 receptor (PLA2R)-negative membranous nephropathy in European and North American populations. The prevalence of THSD7A in other populations and their clinical associations deserve further clarification. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Immunofluorescence assay was performed to investigate anti-THSD7A antibodies in 578 consecutive patients with biopsy-proven idiopathic membranous nephropathy, 114 patients with secondary membranous nephropathy, 64 disease controls, and 20 healthy controls...
August 11, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28798221/egfr-and-albuminuria-in-relation-to-risk-of-incident-atrial-fibrillation-a-meta-analysis-of-the-jackson-heart-study-the-multi-ethnic-study-of-atherosclerosis-and-the-cardiovascular-health-study
#4
Nisha Bansal, Leila R Zelnick, Alvaro Alonso, Emelia J Benjamin, Ian H de Boer, Rajat Deo, Ronit Katz, Bryan Kestenbaum, Jehu Mathew, Cassianne Robinson-Cohen, Mark J Sarnak, Michael G Shlipak, Nona Sotoodehnia, Bessie Young, Susan R Heckbert
BACKGROUND AND OBJECTIVES: The incidence of atrial fibrillation is high in ESRD, but limited data are available on the incidence of atrial fibrillation across a broad range of kidney function. Thus, we examined the association of eGFR and urine albumin-to-creatinine ratio with risk of incident atrial fibrillation. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We meta-analyzed three prospective cohorts: the Jackson Heart Study, the Multi-Ethnic Study of Atherosclerosis, and the Cardiovascular Health Study...
August 10, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28798220/vascular-access-type-and-clinical-outcomes-among-elderly-patients-on-hemodialysis
#5
Timmy Lee, Mae Thamer, Qian Zhang, Yi Zhang, Michael Allon
BACKGROUND AND OBJECTIVES: The optimal type of initial permanent access for hemodialysis among the elderly is controversial. Duration of central venous catheter dependence, patient comorbidities, and life expectancy are important considerations in whether to place an arteriovenous fistula or graft. We used an observational study design to compare clinical outcomes in elderly patients who initiated hemodialysis with a central venous catheter and subsequently had an arteriovenous fistula or graft placed...
August 10, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28794000/the-making-dialysis-safer-for-patients-coalition-a-new-partnership-to-prevent-hemodialysis-related-infections
#6
Priti R Patel, Kristin Brinsley-Rainisch
The Making Dialysis Safer for Patients Coalition is a partnership of organizations and individual stakeholders that share the common goal to prevent bloodstream infections among patients receiving hemodialysis. Led by the Centers for Disease Control and Prevention (CDC), in collaboration with the CDC Foundation, this public-private partnership strives to improve adherence to evidence-based recommendations, share information and experiences, and engage patients in infection prevention efforts.
August 9, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28793999/association-of-qt-prolonging-medication-use-in-ckd-with-electrocardiographic-manifestations
#7
Soren Snitker, Rebecca M Doerfler, Elsayed Z Soliman, Rajat Deo, Wendy L St Peter, Susan Kramlik, Michael J Fischer, Sankar Navaneethan, Patrice Delafontaine, Bernard G Jaar, Akinlolu Ojo, Gail K Makos, Anne Slaven, Matthew R Weir, Min Zhan, Jeffrey C Fink
BACKGROUND AND OBJECTIVES: Several drugs used in CKD can prolong electrocardiographic conduction. We examined the use of electrocardiogram QT-prolonging medications in predialysis CKD and their association with QT duration. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: In total, 3252 Chronic Renal Insufficiency Cohort participants with at least one study electrocardiogram between 2003 and 2011 were included. QT-prolonging medications used in 100 or more visits (n=16,451 visits) along with diuretics and proton pump inhibitors, given their potential for electrolyte disturbances, were examined for QT interval prolongation...
August 9, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28793998/the-clinical-and-mutational-spectrum-of-turkish-patients-with-cystinosis
#8
Rezan Topaloglu, Bora Gulhan, Mihriban İnözü, Nur Canpolat, Alev Yilmaz, Aytül Noyan, İsmail Dursun, İbrahim Gökçe, Metin Kaya Gürgöze, Nurver Akinci, Esra Baskin, Erkin Serdaroğlu, Beltinge Demircioğlu Kiliç, Selçuk Yüksel, Duygu Övünç Hacihamdioğlu, Emine Korkmaz, Mutlu Hayran, Fatih Ozaltin
BACKGROUND AND OBJECTIVES: Infantile nephropathic cystinosis is a severe disease that occurs due to mutations in the cystinosis gene, and it is characterized by progressive dysfunction of multiple organs; >100 cystinosis gene mutations have been identified in multiple populations. Our study aimed to identify the clinical characteristics and spectrum of cystinosis gene mutations in Turkish pediatric patients with cystinosis. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We identified the clinical characteristics and spectrum of cystinosis gene mutations in Turkish patients with cystinosis in a multicenter registry that was established for data collection...
August 9, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28790130/perspective-on-nephrology-fellowship-in-the-united-states
#9
Michel Chonchol
No abstract text is available yet for this article.
August 8, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28790129/perspectives-on-the-nephrology-match-for-fellowship-applicants
#10
Michael J Ross, Gregory Braden
No abstract text is available yet for this article.
August 8, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28784658/what-is-the-role-of-vitamin-d-supplementation-on-vascular-health-in-ckd
#11
EDITORIAL
Nigel D Toussaint, Irene Ruderman
No abstract text is available yet for this article.
August 7, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28784657/cholecalciferol-calcitriol-and-vascular-function-in-ckd-a-randomized-double-blind-trial
#12
Jessica Kendrick, Emily Andrews, Zhiying You, Kerrie Moreau, Kristen L Nowak, Heather Farmer-Bailey, Douglas R Seals, Michel Chonchol
BACKGROUND AND OBJECTIVES: High circulating vitamin D levels are associated with lower cardiovascular mortality in CKD, possibly by modifying endothelial function. We examined the effect of calcitriol versus cholecalciferol supplementation on vascular endothelial function in patients with CKD. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We performed a prospective, double-blind, randomized trial of 128 adult patients with eGFR=15-44 ml/min per 1.73 m(2)and serum 25-hydroxyvitamin D level <30 ng/ml at the University of Colorado...
August 7, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28784656/fibroblast-growth-factor-23-and-anemia-in-the-chronic-renal-insufficiency-cohort-study
#13
Rupal Mehta, Xuan Cai, Alexander Hodakowski, Jungwha Lee, Mary Leonard, Ana Ricardo, Jing Chen, Lee Hamm, James Sondheimer, Mirela Dobre, Valentin David, Wei Yang, Alan Go, John W Kusek, Harold Feldman, Myles Wolf, Tamara Isakova
BACKGROUND AND OBJECTIVES: Anemia is an early complication of CKD that is associated with increased morbidity and mortality. Prior data show associations between abnormal mineral metabolism markers and decreased erythropoiesis. However, few studies have investigated elevated fibroblast growth factor 23 as a risk factor for the development of anemia in patients with CKD. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We conducted a prospective cohort study of 3869 individuals with mild to severe CKD enrolled in the Chronic Renal Insufficiency Cohort Study between 2003 and 2008 and followed through 2013...
August 7, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28784655/endothelium-dependent-and-independent-vascular-function-in-advanced-chronic-kidney-disease
#14
Tal Kopel, James S Kaufman, Naomi Hamburg, John S Sampalis, Joseph A Vita, Laura M Dember
BACKGROUND AND OBJECTIVES: CKD is associated with increased cardiovascular risk not fully attributable to traditional risk factors. We compared endothelium-dependent and -independent vascular function among individuals with advanced CKD with function in those with vascular disease but preserved kidney function. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Matched cohort analysis randomly selected from 1259 participants at a single center with measurements of brachial artery flow-mediated dilation, an endothelium-dependent process, and nitroglycerin-mediated dilation, an endothelium-independent process...
August 7, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28784654/a-rebuttal-to-the-ckd-classification-system-in-the-precision-medicine-era
#15
Andrew S Levey, Adeera Levin
No abstract text is available yet for this article.
August 7, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28784653/a-patient-with-a-novel-gene-mutation-leading-to-autosomal-dominant-polycystic-kidney-disease
#16
Bharathi V Reddy, Arlene B Chapman
No abstract text is available yet for this article.
August 7, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28778854/pragmatic-randomized-controlled-trial-of-patient-navigators-and-enhanced-personal-health-records-in-ckd
#17
Sankar D Navaneethan, Stacey E Jolly, Jesse D Schold, Susana Arrigain, Georges Nakhoul, Victoria Konig, Jennifer Hyland, Yvette K Burrucker, Priscilla Davis Dann, Barbara H Tucky, John Sharp, Joseph V Nally
BACKGROUND AND OBJECTIVES: Patient navigators and enhanced personal health records improve the quality of health care delivered in other disease states. We aimed to develop a navigator program for patients with CKD and an electronic health record-based enhanced personal health record to disseminate CKD stage-specific goals of care and education. We also conducted a pragmatic randomized clinical trial to compare the effect of a navigator program for patients with CKD with enhanced personal health record and compare their combination compared with usual care among patients with CKD stage 3b/4...
August 4, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28778853/the-times-they-are-a-changin-innovations-in-health-care-delivery-to-reduce-ckd-progression
#18
EDITORIAL
Khaled Abdel-Kader
No abstract text is available yet for this article.
August 4, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28775128/refining-diagnostic-approaches-in-nephrolithiasis-incomplete-distal-renal-tubular-acidosis
#19
EDITORIAL
David S Goldfarb
No abstract text is available yet for this article.
August 3, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28775127/correction
#20
(no author information available yet)
No abstract text is available yet for this article.
August 3, 2017: Clinical Journal of the American Society of Nephrology: CJASN
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