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Women's Health

Kamilla Rognmo, Børge Sivertsen, Malin Eberhard-Gran
No abstract text is available yet for this article.
September 15, 2016: Women's Health
Lara Passos Alvim, Thais Izidoro Pires, Cynthia Savioli, Maria Das Graças Afonso Miranda Chaves, Gisele Maria Campos Fabri
No abstract text is available yet for this article.
September 15, 2016: Women's Health
Edward Pavlik
No abstract text is available yet for this article.
September 5, 2016: Women's Health
Terry M Silvestrin, Anna W Steenrod, Karin S Coyne, David E Gross, Canan B Esinduy, Angela B Kodsi, Gayle J Slifka, Lucy Abraham, Anna L Araiza, Andrew G Bushmakin, Xuemei Luo
No abstract text is available yet for this article.
August 24, 2016: Women's Health
Omar El Tokhy, Julia Kopeika, Tarek El-Toukhy
No abstract text is available yet for this article.
August 19, 2016: Women's Health
Omer Ozkan, Nasuh Utku Dogan, Ozlenen Ozkan, Inanc Mendilcioglu, Selen Dogan, Batu Aydinuraz, Mehmet Simsek
Absolute uterine factor infertility affects 3-5% of the general population, and unfortunately this condition is untreatable. There are some available options, including surrogacy or adoption, but neither of these suits each and every woman who desires to have her own genetic child. With recent advances in surgery and transplant immunology, uterus transplantation may be a source of hope for these women with uterine infertility. In the last decade, a number of animal species including rats, mice, rabbits, pigs, sheep, and primates have been used as experimental models, and pregnancies were achieved in some of these...
July 2016: Women's Health
Laura Ormesher, Louise Simcox, Clare Tower, Ian A Greer
Adverse pregnancy outcomes, such as pregnancy loss and pre-eclampsia, are associated with thrombotic mechanisms and thrombophilia. Antithrombotic interventions, particularly low-molecular-weight heparin, have been investigated in women identified by previous pregnancy outcome; however, the results have been inconsistent. This may reflect heterogeneity of both the study groups and the disease processes resulting in inadequate stratification to guide antithrombotic interventions. Furthermore, the variation in gestation at initiation of low-molecular-weight heparin treatment might be important...
July 2016: Women's Health
Shadi Rezai, Stephen LoBue, Cassandra E Henderson
In the United States, 29.1 million people are affected by diabetes, of which 95% have type 2 diabetes. There has been a fivefold increase in type 2 diabetes in the latter half of the 20th century, an increase strongly linked to the obesity epidemic in the United States. In addition, insulin resistance affects 86 million Americans, or more than one-third of the adult population, as manifested by impaired fasting glucose tolerance with random glucose values ranging from ⩾100 to <126 mg/dL. In all, 90% of those affected by impaired fasting glucose tolerance or pre-diabetes are unaware of their metabolic derangement...
July 2016: Women's Health
Allison C Petrini, Nigel Pereira, Jovana P Lekovich, Rony T Elias, Steven D Spandorfer
The primary objective of this study is to investigate whether early spontaneous multiple fetal pregnancy reduction, also known as vanishing twin syndrome, is associated with adverse perinatal outcomes in fresh in vitro fertilization cycles. This is a retrospective cohort study of women with live singleton births with and without an early vanishing twin after fresh in vitro fertilization. Characteristics compared included incidence of preterm birth, overall birth weight, overall low birth weight, overall very low birth weight, and term low birth weight...
July 2016: Women's Health
Daniel Spadoto-Dias, Flávia Neves Bueloni-Dias, Leonardo Vieira Elias, Nilton José Leite, Waldir Pereira Modotti, Ricardo Bassil Lasmar, Rogério Dias
Several studies have demonstrated that the combination of hysteroscopy with endometrial biopsy is more accurate in differentiating endometrial polyps from endometrial hyperplasia and cancer. However, blind biopsy not always confirms hysteroscopic findings due to high rates of inadequate or insufficient material. The objective of this clinical, prospective, and comparative study was to establish a correlation between the histological results of office-based endometrial biopsies (hysteroscopically guided and blind) with the surgical polypectomy specimens...
July 2016: Women's Health
Sana Qureshi, Mahsa Kanzali, Syed Farhan Rizvi, Niharika Joolukuntla, Barry Fomberstein
We report here an unusual case of rheumatoid arthritis presenting for the first time in a 32-week pregnant patient. Despite thorough evaluations from different specialties, the patient's diagnosis went undiscovered originally being attributed to orthopedic issues and then to normal symptoms of pregnancy. The patient's symptoms progressively worsened until she was no longer able to ambulate and complete her daily activities. A primary diagnosis of rheumatoid arthritis is exceedingly rare during pregnancy due to changes in the body's immune system that accommodate the foreign fetus...
July 2016: Women's Health
Nigel Pereira, Isaac Kligman
Several variations in fallopian tube anatomy may be noted during the evaluation of infertility. Some anatomical variants such as accessory tubal ostia are rare. A 31-year-old woman presented to our center with a 2-year history of primary infertility. Given her history of dysmenorrhea, a diagnostic laparoscopy was performed. Laparoscopy revealed a left utero-sacral endometriosis implant, which was resected. Although the left fallopian tube was normal, the right fallopian tube was noted to have two prongs with individual ostia...
July 2016: Women's Health
Yasmina Mohan, Vicki Y Chiu, Neal M Lonky
Hysterectomy is the second most common gynecologic surgery; approximately 600,000 women undergo hysterectomies each year in the United States. Estimated uterine size, either by bimanual examination, ultrasonography, or both, is one of the major factors in evaluating the need for hysterectomy and in selecting the surgical approach. In this article, we review how physician-estimated uterine size can be confidently used in providing optimal hysterectomy care, as data indicate estimation is closely correlated with actual post-surgical pelvic specimen weight...
July 2016: Women's Health
Maurie Markman
A discussion of rational endpoints in clinical trials seeking regulatory approval for new anti-neoplastic agents involving the three major gynecologic malignancies, cancers of the ovary, cervix, and endometrial, is particularly interesting as (in the opinion of this commentator) the conclusion will be different in the individual cancers.
July 2016: Women's Health
Jacqueline L Wolf
No abstract text is available yet for this article.
July 2016: Women's Health
Bhawana Purwar, Vik Khullar
No abstract text is available yet for this article.
June 2016: Women's Health
David Mark Robertson, Robert B Gilchrist, William Leigh Ledger, Angela Baerwald
There is a need to develop rapid protocols for ovarian stimulation for women who wish to preserve their fertility following diagnosis of cancer. Conventional gonadotropin stimulation protocols are lengthy and are delayed until the start of the next menstrual period, potentially compromising cancer treatments. The development of random start IVF/in vitro maturation has made significant strides for enabling couples undergoing cancer therapy to achieve a family. However, several unanswered questions still remain...
June 2016: Women's Health
Gary Ventolini
No abstract text is available yet for this article.
June 2016: Women's Health
Hui Jun Lim, William Ledger
Among female-specific cancers worldwide, ovarian cancer is the leading cause of death from gynecologic malignancy in the western world. Despite radical surgery and initial high response rates to first-line chemotherapy, up to 70% of patients experience relapses with a median progression-free survival of 12-18 months. There remains an urgent need for novel targeted therapies to improve clinical outcomes in ovarian cancer. This review aims to assess current understanding of targeted therapy in ovarian cancer and evaluate the evidence for targeting growth-dependent mechanisms involved in its pathogenesis...
June 2016: Women's Health
Jason R Lefringhouse, Erin Neward, Frederick R Ueland, Lauren A Baldwin, Rachel W Miller, Christopher P DeSimone, Richard J Kryscio, John R van Nagell, Edward J Pavlik
OBJECTIVE: Some ovarian malignancies may originate in the fallopian tube. The feasibility of ultrasonographically visualizing the fallopian tube is presented. METHODS: In total, 549 normal women participated in the fallopian tube visualization trial, while ovarian visualization was studied in 43,521. Chi-square analysis, t-tests and multivariate analysis determined significance and interactions. RESULTS: Ovaries were observed in 82.7% while fallopian tubes were detected in 77...
June 2016: Women's Health
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