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Current Opinion in HIV and AIDS

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https://www.readbyqxmd.com/read/28902721/hiv-associated-pulmonary-hypertension
#1
Harish Jarrett, Christopher Barnett
PURPOSE OF REVIEW: HIV-associated pulmonary arterial hypertension (HIV-PAH) is a well-recognized severe cardiovascular complication of HIV infection that confers an adverse prognosis irrespective of the stage of disease. This review will summarize the available data on HIV-PAH epidemiology and provide insights into the pathophysiology and therapeutic strategies currently available. RECENT FINDINGS: Patients with HIV are several thousand times more likely to develop HIV-PAH compared to the incidence of idiopathic PAH...
September 11, 2017: Current Opinion in HIV and AIDS
https://www.readbyqxmd.com/read/28863015/heart-failure-in-persons-living-with-hiv-infection
#2
Priscilla Y Hsue, David D Waters
PURPOSE OF REVIEW: To discuss presentation, pathophysiology, complications, and treatment of heart failure in persons living with HIV (PLWHIV) in the antiretroviral therapy (ART) era. RECENT FINDINGS: Since the advent of effective ART and improved longevity, heart failure has become more chronic and insidious and is often characterized by preserved ejection fraction, diastolic dysfunction, and left ventricular (LV) hypertrophy. The mechanism underlying heart failure in the setting of HIV infection remains unknown...
August 31, 2017: Current Opinion in HIV and AIDS
https://www.readbyqxmd.com/read/28832368/are-we-successfully-managing-cardiovascular-disease-in-people-living-with-hiv
#3
Camilla I Hatleberg, Jens D Lundgren, Lene Ryom
PURPOSE OF REVIEW: The aim of this study was to discuss the most recent research in the management of cardiovascular disease (CVD) in people living with HIV (PLWHIV) with a focus on screening, primary and secondary prevention. RECENT FINDINGS: The cause of CVD in PLWHIV is complex and multifactorial and creates a demand for a multifaceted approach to screening and prevention. Current screening and management of CVD risk factors in PLWHIV is suboptimal, reasons for this are not clear and the data are still scarce both in the primary and secondary preventive setting...
August 21, 2017: Current Opinion in HIV and AIDS
https://www.readbyqxmd.com/read/28832367/cardiovascular-disease-risk-among-women-living-with-hiv-in-north-america-and-europe
#4
Lauren Stone, Sara E Looby, Markella V Zanni
PURPOSE OF REVIEW: To examine the epidemiology and mechanistic underpinnings of heightened cardiovascular disease (CVD) risk among women living with HIV (WLHIV) in North America and Europe. RECENT FINDINGS: WLHIV in North America and Europe exhibit high CVD incidence rates, which are at par with those of compatriot men living with HIV. Compared with uninfected women, WLHIV in these regions face a 2-4-fold increased relative risk for myocardial infarction, stroke, and heart failure...
August 21, 2017: Current Opinion in HIV and AIDS
https://www.readbyqxmd.com/read/28832366/hiv-and-myocarditis
#5
Ntobeko A B Ntusi
PURPOSE OF REVIEW: The purpose of this article is to review the literature on HIV and myocarditis and HIV-associated heart failure. RECENT FINDINGS: Currently, 17 million people are receiving antiretroviral therapy (ART) globally. There is a decrease in mortality from HIV in the last decade with increased survival in those receiving ART. HIV-associated cardiac failure is on the increase, with more cases of diastolic dysfunction reported in the ART era. The pathophysiology of HIV-associated myocarditis is multifactorial...
August 21, 2017: Current Opinion in HIV and AIDS
https://www.readbyqxmd.com/read/28799999/features-of-cardiovascular-disease-in-low-income-and-middle-income-countries-in-adults-and-children-living-with-hiv
#6
Andrew W McCrary, Chidozie U Nduka, Saverio Stranges, Gerald S Bloomfield
PURPOSE OF REVIEW: The current article addresses crucial issues in identifying risk of cardiovascular disease (CVD) in people living with HIV in low-income and middle-income countries (LMICs). These issues are in need of urgent attention to advance our knowledge and inform actions to mitigate CVD in this population. We address CVDs in adults living with HIV as well as the unique aspects pertaining to children living with HIV (CLHIV), a group sorely under-represented in this field. RECENT FINDINGS: CVDs affecting adults such as hypertension, dyslipidemia, coronary artery disease, and heart failure, in addition to myocardial dysfunction, vascular diseases, and autoimmune phenomena are also being reported in CLHIV...
August 10, 2017: Current Opinion in HIV and AIDS
https://www.readbyqxmd.com/read/28799998/use-of-direct-oral-anticoagulants-for-treatment-of-atrial-fibrillation-in-patients-with-hiv-a-review
#7
Timothy A West, Jacinta Perram, Cameron J Holloway
PURPOSE OF REVIEW: Atrial fibrillation is increasingly common in the ageing population. Patients with atrial fibrillation and HIV have a higher stroke risk, with guidelines recommending anticoagulation in the majority. Whilst anticoagulation options have diversified in the last decade for the general population, there is limited evidence for the safety and efficacy of these medications when used concurrently with antiretroviral therapy. We review the potential for patients with HIV on antiretroviral therapy to have direct-acting oral anticoagulations (DOACs)...
August 10, 2017: Current Opinion in HIV and AIDS
https://www.readbyqxmd.com/read/28799997/epidemiology-of-ischemic-heart-disease-in-hiv
#8
Virginia A Triant, Steven K Grinspoon
PURPOSE OF REVIEW: The purpose of this review is to summarize and synthesize recent data on the risk of ischemic heart disease (IHD) in HIV-infected individuals. RECENT FINDINGS: Recent studies in the field demonstrate an increasing impact of cardiovascular disease (CVD) on morbidity and mortality in HIV relative to AIDS-related diagnoses. Studies continue to support an approximately 1.5 to two-fold increased risk of IHD conferred by HIV, with specific risk varying by sex and virologic/immunologic status...
August 10, 2017: Current Opinion in HIV and AIDS
https://www.readbyqxmd.com/read/28799996/tobacco-illicit-drugs-use-and-risk-of-cardiovascular-disease-in-patients-living-with-hiv
#9
Sergio Raposeiras-Roubín, Emad Abu-Assi, Andrés Iñiguez-Romo
PURPOSE OF REVIEW: There is a strong link between HIV, smoking and illicit drugs. This association could be clinically relevant as it may potentiate the risk of cardiovascular diseases (CVD). The purpose of this review is to bring readers up-to-date on issues concerning the cardiovascular risk associated with tobacco and illicit drugs in patients living with HIV (PLHIV), examinating the studies related to this topic published in the last year. RECENT FINDINGS: There is a strong association between smoking and atherosclerotic disease in PLHIV, reducing life expectancy secondary to CVD by up to 6 years...
August 10, 2017: Current Opinion in HIV and AIDS
https://www.readbyqxmd.com/read/28796027/heart-fat-in-hiv-marker-or-mediator-of-risk
#10
Jonathan Buggey, Chris T Longenecker
PURPOSE OF REVIEW: The review aims to summarize the literature describing the clinical impact of cardiac fat depots in patients with HIV infection. RECENT FINDINGS: People living with HIV (PLHIV) have accelerated rates of cardiovascular disease, and are prone to the development of ectopic fat deposition. Specifically, PLHIV have higher volumes of epicardial and intracardiac fat quantified by noninvasive imaging. Higher volumes of epicardial fat may be related to antiretroviral therapy duration and chronic inflammation, independently of other measures of body adiposity such as BMI...
August 8, 2017: Current Opinion in HIV and AIDS
https://www.readbyqxmd.com/read/28787286/hypertension-in-people-living-with-hiv
#11
Rosan A van Zoest, Bert-Jan H van den Born, Peter Reiss
PURPOSE OF REVIEW: This review describes what is known concerning the burden of hypertension among people living with HIV (PLHIV), and also addresses relevant topics with respect to its risk factors and clinical management. RECENT FINDINGS: Hypertension is highly prevalent in HIV-positive populations, and may be more common than in HIV-negative populations. Risk factors contributing to the development of hypertension in PLHIV include demographic factors, genetic predisposition, lifestyle, comorbidities such as obesity, antiretroviral therapy-related changes in body composition, and potentially also immunodeficiency, immune activation and inflammation, as well as effects from antiretroviral therapy itself...
August 4, 2017: Current Opinion in HIV and AIDS
https://www.readbyqxmd.com/read/28771450/point-of-care-diagnostics-extending-the-laboratory-network-to-reach-the-last-mile-erratum
#12
(no author information available yet)
No abstract text is available yet for this article.
September 2017: Current Opinion in HIV and AIDS
https://www.readbyqxmd.com/read/28771449/using-technology-to-assess-and-intervene-with-illicit-drug-using-persons-at-risk-for-hiv
#13
Keith J Horvath, Sara Lammert, Sara LeGrand, Kathryn E Muessig, José A Bauermeister
PURPOSE OF REVIEW: This review describes recent literature on novel ways technology is used for assessment of illicit drug use and HIV risk behaviours, suggestions for optimizing intervention acceptability, and recently completed and ongoing technology-based interventions for drug-using persons at risk for HIV and others with high rates of drug use and HIV risk behaviour. RECENT FINDINGS: Among studies (n = 5) comparing technology-based to traditional assessment methods, those using Ecological Momentary Assessment (EMA) had high rates of reported drug use and high concordance with traditional assessment methods...
September 2017: Current Opinion in HIV and AIDS
https://www.readbyqxmd.com/read/28771448/mark-wainberg
#14
Douglas D Richman, Robert C Gallo
No abstract text is available yet for this article.
September 2017: Current Opinion in HIV and AIDS
https://www.readbyqxmd.com/read/28767489/editorial-introductions
#15
(no author information available yet)
No abstract text is available yet for this article.
September 2017: Current Opinion in HIV and AIDS
https://www.readbyqxmd.com/read/28692490/the-future-of-digital-games-for-hiv-prevention-and-care
#16
Lisa B Hightow-Weidman, Kathryn E Muessig, José A Bauermeister, Sara LeGrand, Lynn E Fiellin
PURPOSE OF REVIEW: Although there has been a significant increase in mHealth interventions addressing the HIV prevention and care continuum, interventions using game mechanics have been less explored. Digital games are rapidly becoming an important tool for improving health behaviors and supporting the delivery of care and education. The purpose of this review is to provide a historical context for the use of gamification and videogames (including those using virtual reality) used in technology-based HIV interventions and to review new research in the field...
September 2017: Current Opinion in HIV and AIDS
https://www.readbyqxmd.com/read/28682799/online-to-offline-models-in-hiv-service-delivery
#17
Tarandeep Anand, Chattiya Nitpolprasert, Nittaya Phanuphak
PURPOSE OF REVIEW: Half the world's population has access to Internet and technologies, and utilization is near-ubiquitous among providers and key populations. Despite being so well connected; identifying, reaching and linking vulnerable populations to HIV clinical services remains a global challenge. This review highlights the emerging online-to-offline (O2O) models, their potential in scaling up services, and evaluating impact, and implications for future research. RECENT FINDINGS: Globally, four major types of O2O models have been implemented, primarily in the West and Asia, especially among MSM and transgender women...
September 2017: Current Opinion in HIV and AIDS
https://www.readbyqxmd.com/read/28650347/electronic-health-telemedicine-and-new-paradigms-for-training-and-care
#18
Catherine S Todd, Stephen J Mills, Anh L Innes
PURPOSE OF REVIEW: HIV prevention and care is changing rapidly; guideline revisions and programmatic scale-up require innovative approaches to in-service training and care extension to improve provider practice and care access. We assessed recent (≤12 months) peer-reviewed publications on electronic health (eHealth), telemedicine, and other innovative provider-targeted interventions for HIV-related care. RECENT FINDINGS: Key developments included systems merging electronic medical records (EMR) with provider clinical decision aids to prompt action, demonstration eHealth, and telemedicine projects, reviews or descriptions of technology to improve connectivity in lower resource settings, and a few trials on provider-centered interventions...
September 2017: Current Opinion in HIV and AIDS
https://www.readbyqxmd.com/read/28650346/real-time-monitoring-through-the-use-of-technology-to-enhance-performances-throughout-hiv-cascades
#19
Matthew Avery, Stephen J Mills, Eric Stephan
PURPOSE OF REVIEW: Controlling the HIV epidemic requires strong linkages across a 'cascade' of prevention, testing, and treatment services. Information and communications technology (ICT) offers the potential to monitor and improve the performance of this HIV cascade in real time. We assessed recent (<18 months) peer-reviewed publications regarding uses of ICT to improve performance through expanded and targeted reach, improved clinical service delivery, and reduced loss to follow-up...
September 2017: Current Opinion in HIV and AIDS
https://www.readbyqxmd.com/read/28639990/recent-mobile-health-interventions-to-support-medication-adherence-among-hiv-positive-msm
#20
Kathryn E Muessig, Sara LeGrand, Keith J Horvath, José A Bauermeister, Lisa B Hightow-Weidman
PURPOSE OF REVIEW: We describe recent mobile health (mHealth) interventions supporting antiretroviral therapy (ART) medication adherence among HIV-positive MSM. RECENT FINDINGS: Keyword searches (1 January 2016-13 May 2017) identified 721 citations. Seven publications reporting on six studies met inclusion criteria. Five studies focused on MSM. Interventions primarily employed text messaging (n = 4), whereas two focused on smartphone apps and one on social media...
September 2017: Current Opinion in HIV and AIDS
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