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Clinical Research in Cardiology: Official Journal of the German Cardiac Society

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https://www.readbyqxmd.com/read/30203190/cardiovascular-magnetic-resonance-of-cardiac-morphology-and-function-impact-of-different-strategies-of-contour-drawing-and-indexing
#1
Johannes H Riffel, Katharina Schmucker, Florian Andre, Marco Ochs, Kristof Hirschberg, Ebe Schaub, Thomas Fritz, Matthias Mueller-Hennessen, Evangelos Giannitsis, Hugo A Katus, Matthias G Friedrich
BACKGROUND: Cardiovascular magnetic resonance (CMR) is the gold standard for the quantitative assessment of cardiac volumes, mass and function. There are, however, various strategies for establishing endocardial borders, the cardiac phase used for measurements and the body dimensions used for indexing these results. The aim of the study was to assess the impact of different strategies on reference values. METHODS AND RESULTS: 362 healthy volunteers (190 men, mean age 51 ± 13 years) underwent a standard CMR protocol...
September 10, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/30194475/long-term-symptom-improvement-and-patient-satisfaction-after-av-node-ablation-vs-pulmonary-vein-isolation-for-symptomatic-atrial-fibrillation-results-from-the-german-ablation-registry
#2
Kristina Wasmer, M Hochadel, H Wieneke, S G Spitzer, J Brachmann, F Straube, J Tebbenjohanns, G Groschup, A Heisel, T Lewalter, J Senges, L Eckardt
BACKGROUND: We aimed to compare patient characteristics and outcome of patients who had either undergone pulmonary vein isolation (PVI) or AV-node ablation (AVN) to control AF-related symptoms. METHODS: From the German Ablation Registry, we analyzed data of 4444 patients (95%) who had undergone PVI and 234 patients (5%) with AVN. RESULTS: AVN patients were on average 10 years older than PVI patients (71 ± 10 vs. 61 ± 10 years, p < 0...
September 7, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/30191296/invasive-hemodynamics-and-cardiac-biomarkers-to-predict-outcomes-after-percutaneous-edge-to-edge-mitral-valve-repair-in-patients-with-severe-heart-failure
#3
Michael M Kreusser, Nicolas A Geis, Nicolas Berlin, Sebastian Greiner, Sven T Pleger, Raffi Bekeredjian, Hugo A Katus, Philip W Raake
BACKGROUND: Percutaneous mitral valve repair (PMVR) via MitraClip implantation is a therapeutic option for high-risk or non-surgical candidates with severe mitral regurgitation (MR) and advanced stages of heart failure (HF). However, these patients have a high mortality despite PMVR, and predictors for outcomes are not well established. Here, we evaluated invasive hemodynamics, echocardiography parameters, and biomarkers to predict outcomes after PMVR in severe HF patients. METHODS: Patients with reduced ejection fraction (EF) and severe and moderate-to-severe MR undergoing PMVR at our centre between September 2009 and January 2016 were analysed retrospectively...
September 6, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/30187179/coronary-ct-angiography-ccta-using-third-generation-dual-source-ct-for-ruling-out-in-stent-restenosis
#4
J Eckert, P Renczes-Janetzko, M Schmidt, A Magedanz, T Voigtländer, A Schmermund
AIMS: Late in-stent restenosis (ISR) has become increasingly important, in particular due to neo-atherosclerosis. CCTA is a highly sensitive method for detecting coronary plaques. Its diagnostic accuracy regarding ISR is controversial. Stent artifacts can impede image quality, but recent developments in CT-technology may help to overcome some of these problems and allow for improved diagnostic accuracy. METHODS: Consecutive patients after previous coronary revascularization who had stable symptoms or signs of possible disease progression were examined using a third-generation dual-source CT scanner...
September 5, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/30187178/safety-and-efficacy-of-cryoballoon-ablation-for-the-treatment-of-atrial-fibrillation-in-elderly-patients
#5
Amr Abdin, Kivanc Yalin, Evgeny Lyan, Noureddin Sawan, Sypridon Liosis, Roza Meyer-Saraei, Christian Elsner, Stefan A Lange, Christian-Hendrik Heeger, Charlotte Eitel, Ingo Eitel, Roland Richard Tilz
BACKGROUND: Catheter ablation (CA) is an established therapy for treatment of atrial fibrillation (AF). However, data about AF ablation using the cryoballoon (CB) in the elderly population are sparse. The aim of this single center retrospective study is to evaluate the safety and efficacy of CB ablation in patients ≥ 75 years compared to patients < 75 years. METHODS AND RESULTS: Fifty-five consecutive patients aged ≥ 75 years (elderly group) were compared with 183 patients aged < 75 years (control group)...
September 5, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/30182165/remaining-challenges-in-catheter-ablation-of-accessory-pathways-rare-entity-of-coronary-sinus-diverticulum-associated-pathways
#6
Patrick Leitz, K Wasmer, J Köbe, D G Dechering, G Frommeyer, F Güner, C Ellermann, F Reinke, L Eckardt
INTRODUCTION: A limited number of case reports of coronary sinus (CS) diverticula complicating catheter ablation have been published. METHODS AND RESULTS: We retrospectively analysed 2245 patients who underwent ablation of an accessory pathway (AP) at our institution between 1/11/1993 and 31/10/2016. Eight patients (0.36%) were found to have a CS diverticulum in venography. APs showed a mean antegrade conduction time of 276 ± 23 ms (range 220-310 ms) and a mean retrograde conduction of 301 ± 45 ms (230-350 ms)...
September 4, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/30182164/computed-tomography-angiography-for-guiding-and-follow-up-of-magnesium-bioresorbable-scaffold-implantation
#7
LETTER
Maksymilian P Opolski, Cezary Kepka, Wojtek Wojakowski, Adam Witkowski
No abstract text is available yet for this article.
September 4, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/30182163/correction-to-transcatheter-valve-in-valve-implantation-vinv-tavr-for-failed-surgical-aortic-bioprosthetic-valves
#8
Bernhard Wernly, Ann-Katrin Zappe, Axel Unbehaun, Jan-Malte Sinning, Christian Jung, Won-Keun Kim, Stephan Fichtlscherer, Michael Lichtenauer, Uta C Hoppe, Brunilda Alushi, Frederik Beckhoff, Charlotte Wewetzer, Marcus Franz, Daniel Kretzschmar, Eliano Navarese, Ulf Landmesser, Volkmar Falk, Alexander Lauten
Unfortunately, an error occurred in the original article.
September 4, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/30159751/remote-vs-conventional-navigation-for-catheter-ablation-of-atrial-fibrillation-insights-from-prospective-registry-data
#9
Jan-Hendrik van den Bruck, Arian Sultan, Jakob Lüker, Dierk Thomas, Stephan Willems, Kai Weinmann, Malte Kuniss, Matthias Hochadel, Jochen Senges, Dietrich Andresen, Johannes Brachmann, Karl-Heinz Kuck, Roland Tilz, Daniel Steven
BACKGROUND: Robotic (RNS) or magnetic navigation systems (MNS) are available for remotely performed catheter ablation for atrial fibrillation (AF). OBJECTIVE: The present study compares remotely assisted catheter navigation (RAN) to standard manual navigation (SMN) and both systems amongst each other. METHODS: The analysis is based on a sub-cohort enrolled by five hospitals from the multicenter German ablation Registry. RESULTS: Out of 2442 patients receiving catheter ablation of AF, 267 (age 61...
August 29, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/30155733/correction-to-heart-valve-disease-awareness-survey-2017-what-did-we-achieve-since-2015
#10
Luise Gaede, Lars Aarberge, George Brandon Bravo Bruinsma, Philip Macarthy, Francesco Musumeci, Pepe Zamorano, Helge Möllmann
The first and last names of all authors were interchanged in the original publication.
August 28, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/30155732/prophylactic-ecmo-during-tavi-in-patients-with-depressed-left-ventricular-ejection-fraction
#11
Teresa Trenkwalder, Costanza Pellegrini, Andreas Holzamer, Tobias Rheude, Josef Riester, Wibke Reinhard, N Patrick Mayr, Albert M Kasel, Luise Gaede, Johannes Blumenstein, Adnan Kastrati, Heribert Schunkert, Michael Joner, Michael Hilker, Christian Hengstenberg, Oliver Husser
BACKGROUND: This study investigated the impact of prophylactic veno-arterial extracorporeal membrane oxygenation (pECMO) in patients with depressed left ventricular ejection fraction (dLVEF) undergoing transcatheter aortic valve implantation (TAVI). METHODS: Out of 1490 patients undergoing TAVI at two centers (2010-2015), 222 patients had dLVEF (≤ 40%). Of these, 21 patients (10%) underwent TAVI with pECMO. Complications and outcome according to pECMO were analyzed in the entire and in a propensity-matched population...
August 28, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/30167808/clinical-and-economical-impact-of-the-presence-of-an-extended-heart-team-throughout-the-balloon-expandable-transcatheter-aortic-valve-implantation-procedure
#12
Michal Droppa, Oliver Borst, Thomas Katzenberger, Roland Krause, Karin Bramlage, Peter Bramlage, Henning F Lausberg, Christian Schlensak, Christian Grasshoff, Meinrad Gawaz, Tobias Geisler
BACKGROUND: Transcatheter aortic valve implantation (TAVI) is a standard therapy for aortic valve stenosis in patients at intermediate-to-high surgical risk. Previously, TAVI at our site was performed by a minimalist heart team (MHT), comprised of two interventional cardiologists, echocardiography staff and two cardiac catheterization laboratory nurses. After revision of German Federal Joint Committee (G-BA) guidelines in September 2015, the presence of an extended heart team (EHT; including a full cardiac surgical team) became mandatory throughout the TAVI procedure...
August 24, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/30167807/influence-of-baseline-systolic-blood-pressure-on-the-relationship-between-intensive-blood-pressure-control-and-cardiovascular-outcomes-in-the-systolic-blood-pressure-intervention-trial-sprint
#13
Xiuting Sun, Yue Guo, Zhiqiang Nie, Jing Cheng, Huimin Zhou, Xiangbin Zhong, Shaozhan Zhang, Zhimin Du, Xiaodong Zhuang, Xinxue Liao
OBJECTIVE: To determine whether the effects of intensive (< 120 mmHg) compared with standard (< 140 mmHg) systolic blood pressure (SBP) treatments are different among those with different baseline SBP. METHODS: De-identified SPRINT database was used for this post hoc analysis. SPRINT participants were categorized by baseline SBP status, defined as high-SBP (≥ 140 mmHg) group versus the low-SBP (< 140 mmHg) group. The primary outcome was a composite of myocardial infarction, acute coronary syndrome not resulting in myocardial infarction, stroke, acute decompensated heart failure, or death from cardiovascular causes...
August 24, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/30167806/physical-inactivity-and-smoking-after-myocardial-infarction-as-predictors-for-readmission-and-survival-results-from-the-swedeheart-registry
#14
Amanda Ek, Örjan Ekblom, Kristina Hambraeus, Åsa Cider, Lena V Kallings, Mats Börjesson
BACKGROUND: Physical activity (PA) and smoking cessation are included in the secondary prevention guidelines after myocardial infarction (MI), but they are still underutilised. This study aims to explore how PA level and smoking status (6-10 weeks post-MI) were associated with 1-year readmission and mortality during full follow-up time, and with the cumulative 5-year mortality. METHODS: A population-based cohort of all hospitals providing MI-care in Sweden (SWEDEHEART-registry) in 2004-2014...
August 23, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/30167809/extended-ecg-monitoring-with-an-implantable-loop-recorder-in-patients-with-cryptogenic-stroke-time-schedule-reasons-for-explantation-and-incidental-findings-results-from-the-track-af-trial
#15
Markus Bettin, Dirk Dechering, Simon Kochhäuser, Niklas Bode, Lars Eckardt, Gerrit Frommeyer, Florian Reinke
BACKGROUND: Implantable loop recorders (ILR) may be used to detect occult atrial fibrillation (AF) in patients with cryptogenic stroke. At present, there has been no description on the incidental findings of stored episodes in these patients. Furthermore, no standard practice has been established with respect to the duration of continued ECG monitoring in these patients. MATERIALS AND METHODS: In the prospective monocentric study (TRACK-AF), a total of 173 patients with cryptogenic stroke received an ILR for detection of AF between November 2010 and December 2014...
August 22, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/30135995/exercise-in-individuals-with-atrial-fibrillation
#16
REVIEW
Marius Myrstad, Vegard Malmo, Sara Reinvik Ulimoen, Arnljot Tveit, Jan Pål Loennechen
BACKGROUND: Despite the high prevalence of atrial fibrillation (AF), there is a lack of recommendations for physical activity and exercise in individuals with AF, including athletes with AF. METHODS: With the aim to review studies that have investigated effects and safety of exercise in individuals with AF, we conducted a literature search in Pubmed using the key words atrial fibrillation AND exercise OR physical activity OR exercise/adverse effects OR adverse outcome...
August 22, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/30132063/sex-differences-in-risk-of-incident-venous-thromboembolism-in-heart-failure-patients
#17
Line Melgaard, Peter Brønnum Nielsen, Thure Filskov Overvad, Flemming Skjøth, Gregory Y H Lip, Torben Bjerregaard Larsen
BACKGROUND: In patients with incident heart failure, the risk of venous thromboembolism (VTE), defined as pulmonary embolism (PE) and/or deep venous thrombosis (DVT), is sparsely described, especially potential sex differences. We conducted an observational study to evaluate risk of VTE among male and female heart failure patients. METHODS: Population-based cohort study of patients diagnosed with incident heart failure during 2000-2015, identified by record linkage between nationwide registries in Denmark...
August 21, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/30121697/bromocriptine-treatment-in-patients-with-peripartum-cardiomyopathy-and-right-ventricular-dysfunction
#18
Arash Haghikia, Johannes Schwab, Jens Vogel-Claussen, Dominik Berliner, Tobias Pfeffer, Tobias König, Carolin Zwadlo, Valeska Abou Moulig, Annegret Franke, Marziel Schwarzkopf, Philipp Ehlermann, Roman Pfister, Guido Michels, Ralf Westenfeld, Verena Stangl, Uwe Kühl, Edith Podewski, Ingrid Kindermann, Michael Böhm, Karen Sliwa, Denise Hilfiker-Kleiner, Johann Bauersachs
BACKGROUND: Right ventricular (RV) dysfunction predicts adverse outcome in peripartum cardiomyopathy (PPCM). We recently demonstrated beneficial effects associated with the prolactin release inhibitor bromocriptine at different doses when added to standard heart failure therapy in PPCM. Here, we evaluated for the first time the therapeutic potential of bromocriptine particularly in PPCM patients with RV involvement. METHODS: In this study, 40 patients with PPCM were included, of whom 24 patients had reduced RV ejection fraction (RVEF < 45%)...
August 18, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/30105547/genetic-basis-of-hypertrophic-cardiomyopathy-in-children
#19
Stefan Rupp, Moataz Felimban, Anne Schänzer, Dietmar Schranz, Christoph Marschall, Martin Zenker, Thushiha Logeswaran, Christoph Neuhäuser, Josef Thul, Christian Jux, Andreas Hahn
BACKGROUND: Previous investigations assessing the genetic cause of pediatric hypertrophic cardiomyopathy (HCM) found underlying genetic mutations in 50-60% of cases. The purpose of our study was to analyze whether this number can be augmented by applying next-generation sequencing and directing further diagnostics by discussing unsolved cases in a multidisciplinary board. METHODS AND RESULTS: 42 patients with the diagnoses of HCM made before age 18 years were treated in our center from 2000 to 2016...
August 13, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/30097684/symptom-patterns-and-clinical-outcomes-in-women-versus-men-with-systolic-heart-failure-and-depression
#20
Sven M Piepenburg, Hermann Faller, Stefan Störk, Georg Ertl, Christiane E Angermann
BACKGROUND: Depression is more common in females than in males and is 3-5 times more prevalent in patients with heart failure (HF) than in the general population. The 9-item Patient Health Questionnaire (PHQ-9) is a validated depression screening instrument; higher sum-scores predict adverse clinical outcomes. Sex- and gender differences in PHQ-9 symptom profile, diagnostic and prognostic properties, and impact on health-related quality of life (HRQOL) have not been comprehensively studied in HF patients...
August 10, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
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