journal
MENU ▼
Read by QxMD icon Read
search

Clinical Research in Cardiology: Official Journal of the German Cardiac Society

journal
https://www.readbyqxmd.com/read/28921055/implantation-meets-intervention-reopening-of-a-thrombotic-ostial-occlusion-of-coronary-sinus-by-angioplasty-achieved-improvement-of-cardiac-venous-drainage-and-allowed-transvenous-crt-implantation
#1
LETTER
Wolfgang Kranig, Johannes Amberger, Khaled Awad, Enrik Wolff, Kerstin Vahlkamp, Joachim Thale, Bernhard Küpper
No abstract text is available yet for this article.
September 18, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/28921054/association-of-mineralocorticoid-receptor-antagonist-use-and-in-hospital-outcomes-in-patients-with-acute-heart-failure
#2
Vasiliki Bistola, Panagiotis Simitsis, Dimitrios Farmakis, Ignatios Ikonomidis, Georgios Bakosis, Filippos Triposkiadis, Erifili Hatziagelaki, John Lekakis, Alexandre Mebazaa, John Parissis
Mineralocorticoid receptor antagonists (MRAs) constitute a beneficial therapy in chronic heart failure, but their use in the acute heart failure (AHF) setting remains rather unexplored. To assess the effect of MRAs administered during hospitalization on in-hospital outcomes of patients with AHF, we performed a post-hoc analysis of the Acute Heart Failure Global Registry of Standard Treatment (ALARM-HF). Patients of the original study cohort (n = 4953) were categorized according to in-hospital MRA treatment status as MRA-treated (n = 1439) and untreated (n = 3514) subjects...
September 18, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/28917011/prevalence-predictors-and-prognostic-implications-of-pr-interval-prolongation-in-patients-with-heart-failure
#3
Theodora Nikolaidou, Pierpaolo Pellicori, Jufen Zhang, Syed Kazmi, Kevin M Goode, John G Cleland, Andrew L Clark
AIMS: To determine the prevalence, incidence, predictors, and prognostic implications of PR interval prolongation in patients referred with suspected heart failure. METHODS AND RESULTS: Consecutive patients referred with suspected heart failure were prospectively enrolled. After excluding patients with implantable cardiac devices and atrial fibrillation, 1420 patients with heart failure and reduced ejection fraction (HeFREF) [age: median 71 (interquartile range IQR 63-78) years; men: 71%; NT-ProBNP: 1319 (583-3378) ng/L], 1094 with heart failure and normal ejection fraction (HeFNEF) [age: 76 (70-82) years; men: 47%; NT-ProBNP: 547 (321-1171) ng/L], and 1150 without heart failure [age: 68 (60-75) years; men: 51%; NT-ProBNP: 86 (46-140) ng/L] were included...
September 15, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/28905244/bioresorbable-vascular-scaffold-implantation-to-bail-out-nail-gun-injury-in-st-segment-myocardial-infarction
#4
LETTER
Torsten Schütz, Friedrich P Krönig, Christoph Karmeinsky, Oliver Weingärtner
No abstract text is available yet for this article.
September 13, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/28856443/circadian-rhythm-of-blood-cardiac-troponin-t-concentration
#5
Stephane Fournier, Lea Iten, Pedro Marques-Vidal, Olivier Boulat, Daniel Bardy, Ahmed Beggah, Rachel Calderara, Beata Morawiec, Nathalie Lauriers, Pierre Monney, Juan F Iglesias, Patrizio Pascale, Brahim Harbaoui, Eric Eeckhout, Olivier Muller
INTRODUCTION: High-sensitivity cardiac troponin assays have significantly improved the sensitivity of myocardial infarction detection by using cutoff values and early absolute changes. However, variation in repeated measures also depends on biological variability. This study aimed to assess the potential circadian component of this biological variability. METHODS: 17 healthy volunteers were recruited, and standardized conditions for physical activity, meals, exposure to light and duration of sleep were imposed...
August 30, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/28852839/effect-of-eplerenone-on-extracellular-cardiac-matrix-biomarkers-in-patients-with-acute-st-elevation-myocardial-infarction-without-heart-failure-insights-from-the-randomized-double-blind-reminder-study
#6
João Pedro Ferreira, Kévin Duarte, Gilles Montalescot, Bertram Pitt, Esteban Lopez de Sa, Christian W Hamm, Marcus Flather, Freek Verheugt, Harry Shi, Eva Turgonyi, Miguel Orri, Patrick Rossignol, John Vincent, Faiez Zannad
OBJECTIVE: Aldosterone stimulates cardiac collagen synthesis. Circulating biomarkers of collagen turnover provide a useful tool for the assessment of cardiac remodeling in patients with an acute myocardial infarction (MI). METHODS: The REMINDER trial assessed the effect of eplerenone in patients with an acute ST-elevation Myocardial Infarction (STEMI) without known heart failure (HF), when initiated within 24 h of symptom onset. The primary outcome was almost totally (>90%) driven by natriuretic peptide (NP) thresholds after 1-month post-MI (it also included a composite of cardiovascular death or re-hospitalization or new onset HF or sustained ventricular tachycardia or fibrillation or LVEF ≤40% after 1-month post-MI)...
August 29, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/28849269/multicenter-randomized-comparison-between-magnetically-navigated-and-manually-guided-radiofrequency-ablation-of-atrioventricular-nodal-reentrant-tachycardia-the-magma-avnrt-trial
#7
Tilko Reents, Clemens Jilek, Peter Schuster, Georg Nölker, Katharina Koch-Büttner, Sonia Ammar-Busch, Verena Semmler, Felix Bourier, Marc Kottmaier, Marie Kornmayer, Stephanie Brooks, Stephanie Fichtner, Christof Kolb, Isabel Deisenhofer, Gabriele Hessling
BACKGROUND: Remote magnetic navigation (RMN) is attributed to diminish radiation exposure for both patient and operator performing catheter ablation for different arrhythmia substrates. The purpose of this prospective, randomized study was to compare RMN with manually guided catheter ablation for AV nodal reentrant tachycardia (AVNRT) regarding fluoroscopy time/dosage, acute and long-term efficacy as well as safety. METHODS AND RESULTS: A total of 218 patients with AVNRT undergoing catheter ablation at three centers (male 34%, mean age 50 ± 17 years) were randomized to a manual approach (n = 113) or RMN (n = 105) using the Niobe(®) magnetic navigation system...
August 28, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/28845508/impact-of-renal-denervation-on-tissue-na-content-in-treatment-resistant-hypertension
#8
Christian Ott, Christoph Kopp, Anke Dahlmann, Axel Schmid, Peter Linz, Alexander Cavallaro, Matthias Hammon, Tilmann Ditting, Roland Veelken, Michael Uder, Jens Titze, Roland E Schmieder
OBJECTIVES: Renal denervation (RDN) has been introduced for reducing blood pressure (BP) in treatment-resistant hypertension (TRH). The precise mechanism how RDN exerts its BP-lowering effects are not yet fully understood. It is widely accepted that sodium (Na(+)) plays a crucial role in the pathogenesis of hypertensive disease. However, there is increasing evidence of osmotically inactive Na(+) storage. We investigated the impact of RDN on Na(+) homeostasis using estimation of salt intake, and measurement of tissue Na(+) content...
August 28, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/28840316/clinical-outcomes-associated-with-sarcomere-mutations-in-hypertrophic-cardiomyopathy-a-meta-analysis-on-7675-individuals
#9
Farbod Sedaghat-Hamedani, Elham Kayvanpour, Oguz Firat Tugrul, Alan Lai, Ali Amr, Jan Haas, Tanja Proctor, Philipp Ehlermann, Katrin Jensen, Hugo A Katus, Benjamin Meder
BACKGROUND: Hypertrophic cardiomyopathy (HCM) is the most common genetic cardiovascular disease, which goes along with increased risk for sudden cardiac death (SCD). Despite the knowledge about the different causal genes, the relationship between individual genotypes and phenotypes is incomplete. METHODS AND RESULTS: We retrieved PubMed/Medline literatures on genotype-phenotype associations in patients with HCM and mutations in MYBPC3, MYH7, TNNT2, and TNNI3. Altogether, 51 studies with 7675 HCM patients were included in our meta-analysis...
August 24, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/28828679/transcatheter-aortic-valve-implantation-in-patients-with-a-reduced-left-ventricular-ejection-fraction-a-single-centre-experience-in-2000-patients-tavik-registry
#10
Gerhard Schymik, Panagiotis Tzamalis, Valentin Herzberger, Jens Bergmann, Peter Bramlage, Alexander Würth, Lars Oliver Conzelmann, Armin Luik, Holger Schröfel
BACKGROUND: Previous studies into the effect of a reduced left ventricular ejection fraction (EF) on the short- and long-term prognosis of patients undergoing transcatheter aortic valve implantation (TAVI) have reported conflicting findings. We analysed data from the Karlsruhe TAVI registry with the aim of addressing this question. METHODS AND RESULTS: Patients with aortic stenosis undergoing TAVI were divided into sub-groups according to EF: severely reduced (<30%; n = 109), reduced (≥30 and ≤40%; n = 201), and mid-range/preserved (>40%; n = 1690)...
August 21, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/28808772/longitudinal-strain-assessed-by-cardiac-magnetic-resonance-correlates-to-hemodynamic-findings-in-patients-with-severe-aortic-stenosis-and-predicts-positive-remodeling-after-transcatheter-aortic-valve-replacement
#11
Dominik Buckert, Maciej Cieslik, Raid Tibi, Michael Radermacher, Volker Rasche, Peter Bernhardt, Vinzenz Hombach, Wolfgang Rottbauer, Jochen Wöhrle
AIMS: To assess left-ventricular strain parameters before and after transcatheter aortic valve replacement (TAVR) by feature tracking cardiac magnetic resonance imaging (FT CMR) and to correlate the findings to hemodynamic state and left-ventricular remodeling. METHODS AND RESULTS: Patients with symptomatic AS underwent FT CMR before and after TAVR. Patients were carefully evaluated by a comprehensive work-up including CMR, echocardiography and left and right heart catheterization...
August 14, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/28812145/clarification-on-the-role-of-lv-untwisting-in-lv-relaxation-and-diastolic-filling
#12
LETTER
T Jake Samuel, Eric J Stöhr
No abstract text is available yet for this article.
August 10, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/28795299/adherence-to-optimal-heart-rate-control-in-heart-failure-with-reduced-ejection-fraction-insight-from-a-survey-of-heart-rate-in-heart-failure-in-sweden-hr-hf-study
#13
M Fu, U Ahrenmark, S Berglund, C J Lindholm, A Lehto, A Månsson Broberg, G Tasevska-Dinevska, G Wikstrom, A Ågard, B Andersson
INTRODUCTION: Despite that heart rate (HR) control is one of the guideline-recommended treatment goals for heart failure (HF) patients, implementation has been painstakingly slow. Therefore, it would be important to identify patients who have not yet achieved their target heart rates and assess possible underlying reasons as to why the target rates are not met. MATERIALS AND METHODS: The survey of HR in patients with HF in Sweden (HR-HF survey) is an investigator-initiated, prospective, multicenter, observational longitudinal study designed to investigate the state of the art in the control of HR in HF and to explore potential underlying mechanisms for suboptimal HR control with focus on awareness of and adherence to guidelines for HR control among physicians who focus on the contributing role of beta-blockers (BBs)...
August 9, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/28795259/comparison-of-outcomes-using-balloon-expandable-versus-self-expanding-transcatheter-prostheses-according-to-the-extent-of-aortic-valve-calcification
#14
Won-Keun Kim, Johannes Blumenstein, Christoph Liebetrau, Andreas Rolf, Luise Gaede, Arnaud Van Linden, Mani Arsalan, Mirko Doss, Jan G P Tijssen, Christian W Hamm, Thomas Walther, Helge Möllmann
BACKGROUND: Device landing zone (DLZ) calcification is an important determinant of procedural success in transcatheter aortic valve implantation (TAVI). OBJECTIVE: To evaluate the impact of DLZ calcification on procedural outcome with different types of transcatheter heart valves (THVs). METHODS: Aortic valve calcium density (AVCdens) was determined by non-contrast-enhanced computed tomography in 1232 patients undergoing transfemoral TAVI...
August 9, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/28785812/functional-status-and-quality-of-life-after-transcatheter-mitral-valve-repair-a-prospective-cohort-study-and-systematic-review
#15
Christos Iliadis, Samuel Lee, Kathrin Kuhr, Clemens Metze, Anna-Sophie Matzik, Guido Michels, Volker Rudolph, Stephan Baldus, Roman Pfister
BACKGROUND: Estimating the quantitative effect of transcatheter mitral valve repair on functional parameters and quality of life is important for individual treatment decision-making. METHODS: We combined data from a prospective monocentric cohort study (N = 215) with data from a systematic literature review (PubMed search term "mitraclip", till 30.04.2016) on patients undergoing MitraClip with at least mortality after discharge reported as an outcome. Effects on functional parameters were reported as range of mean change...
August 7, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/28779229/biological-variation-of-extracellular-matrix-biomarkers-in-patients-with-stable-chronic-heart-failure
#16
Tobias Täger, Clara Wiebalck, Hanna Fröhlich, Anna Corletto, Hugo A Katus, Lutz Frankenstein
BACKGROUND: Extracellular matrix (ECM) biomarkers such as matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) are pathophysiological key, prognostic marker and therapeutic target in chronic heart failure (HF). Serial measurements of MMPs and TIMPs may be useful for guidance of these applications. However, interpretation of time-dependent changes requires knowledge about the biological variation of ECM biomarkers. METHODS: We performed measurements of MMP-2, MMP-9, TIMP-1, and TIMP-4 in 50 patients with chronic HF who met rigid criteria for clinical stability at 3-h, 6-h, 1-week and 2-week time intervals...
August 4, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/28776267/outcomes-of-patients-with-periprocedural-atrial-fibrillation-undergoing-percutaneous-coronary-intervention-for-chronic-total-occlusion
#17
Barbara E Stähli, Cathérine Gebhard, Michael Gick, Kambis Mashayekhi, Miroslaw Ferenc, Heinz Joachim Buettner, Franz-Josef Neumann, Aurel Toma
BACKGROUND: Successful CTO recanalization has been associated with clinical benefit. Outcomes of patients with atrial fibrillation undergoing CTO PCI have not been investigated, yet. AIMS: This study sought to evaluate the association between atrial fibrillation and outcomes after percutaneous coronary intervention (PCI) for chronic total occlusions (CTO). METHODS: Consecutive patients undergoing CTO PCI between January 2005 and December 2013 were divided into patients with and without atrial fibrillation, and propensity-matched models used to adjust for baseline differences between groups...
August 3, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/28776266/impact-of-left-main-coronary-artery-disease-on-long-term-mortality-in-patients-undergoing-drug-eluting-stent-implantation
#18
Se Hun Kang, Cheol Whan Lee, Seunghee Baek, Pil Hyung Lee, Jung-Min Ahn, Duk-Woo Park, Soo-Jin Kang, Seung-Whan Lee, Young-Hak Kim, Seong-Wook Park, Seung-Jung Park
BACKGROUND: Limited data are available on long-term mortality according to the extent of coronary artery disease (CAD) in patients undergoing percutaneous coronary intervention (PCI) with drug-eluting stent (DES). We assessed long-term mortality DES implantation according to the extent of CAD and the impact of left main CAD alone on mortality among patients undergoing PCI with DES. METHODS AND RESULTS: A total of 18,716 patients were pooled from real-world PCI registries...
August 3, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/28755285/two-year-follow-up-of-4%C3%A2-months-metformin-treatment-vs-placebo-in-st-elevation-myocardial-infarction-data-from-the-gips-iii-rct
#19
Minke H T Hartman, Jake K B Prins, Remco A J Schurer, Erik Lipsic, Chris P H Lexis, Anouk N A van der Horst-Schrivers, Dirk J van Veldhuisen, Iwan C C van der Horst, Pim van der Harst
OBJECTIVES: Preclinical and clinical studies suggested cardioprotective effects of metformin treatment. In the GIPS-III trial, 4 months of metformin treatment did not improve left ventricular ejection fraction in patients presenting with ST-elevation myocardial infarction (STEMI). Here, we report the 2-year follow-up results. METHODS: Between January 2011 and May 2013, 379 STEMI patients without diabetes undergoing primary percutaneous coronary intervention were randomized to a 4-month treatment with metformin (500 mg twice daily) (N = 191) or placebo (N = 188) in the University Medical Center Groningen...
July 28, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/28752374/erratum-to-serelaxin-in-acute-heart-failure-patients-with-and-without-atrial-fibrillation-a-secondary-analysis-of-the-relax-ahf-trial
#20
Gerasimos Filippatos, Dimitrios Farmakis, Marco Metra, Gad Cotter, Beth A Davison, G Michael Felker, Barry H Greenberg, Tsushung A Hua, Peter S Pang, Piotr Ponikowski, Min Qian, Thomas A Severin, Adriaan A Voors, John R Teerlink
No abstract text is available yet for this article.
July 27, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
journal
journal
41249
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"