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Clinical Research in Cardiology: Official Journal of the German Cardiac Society

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https://www.readbyqxmd.com/read/27896422/transcatheter-aortic-matryoshka-doll-thrombosis
#1
LETTER
Levent Cerit
No abstract text is available yet for this article.
November 28, 2016: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/27888304/the-wearable-cardioverter-defibrillator-in-a-real-world-clinical-setting-experience-in-102-consecutive-patients
#2
Julia W Erath, Mate Vamos, Abdul Sami Sirat, Stefan H Hohnloser
BACKGROUND: The wearable cardioverter-defibrillator (WCD) is used for temporary protection of patients deemed to be at high risk for sudden death (SCD) not yet meeting indications for the implantable defibrillator (ICD). OBJECTIVES: To evaluate the efficacy, safety, and compliance of/to WCD use and subsequent medium-term outcome of patients in a single-center observational study. METHODS: A total of 102 consecutive patients were fitted with the WCD from 2012 to 2015 and followed for a mean of 11 months (±8 months)...
November 25, 2016: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/27878381/posttraumatic-stress-and-quality-of-life-with-the-totally-subcutaneous-compared-to-conventional-cardioverter-defibrillator-systems
#3
Julia Köbe, Katharina Hucklenbroich, Nils Geisendörfer, Markus Bettin, Gerrit Frommeyer, Florian Reinke, Dirk Dechering, Markus Burgmer, Lars Eckardt
BACKGROUND: For prevention of sudden cardiac death, the transvenously implantable cardioverter-defibrillator therapy (tv-ICD) is well accepted. The subcutaneous system (S-ICD(®)) is promising in terms of reducing ICD complications. Nevertheless, the impact of the novel generator position on patients' quality of life (QoL) is yet unknown. OBJECTIVE: This study aimed at comparing QoL and posttraumatic stress with both systems. METHODS: 60 S-ICD(®) and 60 case-controlled tv single-chamber ICD patients were asked to respond to three standardized questionnaires...
November 22, 2016: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/27853943/endocardial-voltage-mapping-of-pulmonary-veins-with-an-ultra-high-resolution-system-to-evaluate-atrial-myocardial-extensions
#4
Francesco Santoro, Christian Sohns, Ardan M Saguner, Natale Daniele Brunetti, Christine Lemes, Shibu Mathew, Christian-H Heeger, Bruno Reißmann, Tilman Maurer, Johannes Riedl, Thomas Fink, Kentaro Hayashi, Feifan Ouyang, Matteo Di Biase, Karl-Heinz Kuck, Andreas Metzner
INTRODUCTION: Atrial fibrillation (AF) is mainly triggered by arrhythmogenic foci originating from atrial myocardial extensions (MEs) into the pulmonary veins (PVs). Aim of the study was to evaluate endocardial voltage maps of PVs as a surrogate parameter for the extent of MEs in subjects with AF through a ultra-high-density mapping system. METHODS: Sixty-four bipolar electrograms were recorded simultaneously from the Orion mini-basket catheter placed in 72 PVs of 18 consecutive patients with paroxysmal/persistent AF undergoing PV isolation (PVI)...
November 16, 2016: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/27853942/course-of-early-subclinical-leaflet-thrombosis-after-transcatheter-aortic-valve-implantation-with-or-without-oral-anticoagulation
#5
Philipp Ruile, Nikolaus Jander, Philipp Blanke, Simon Schoechlin, Jochen Reinöhl, Michael Gick, Juergen Rothe, Mathias Langer, Jonathon Leipsic, Heinz-Joachim Buettner, Franz-Josef Neumann, Gregor Pache
BACKGROUND: After transcatheter aortic valve implantation, early leaflet thickening, presumably reflecting thrombus, has recently been described on computed tomography angiography (CTA) in ~10% of the patients. We sought to investigate the impact of the antithrombotic regimen on the course of leaflet thickening. METHODS: The study comprised 51 patients with leaflet thickening. Based on the time period, patients without an established indication for anticoagulation were put on phenprocoumon plus clopidogrel for at least 3 months or on dual antiplatelet therapy with aspirin and clopidogrel...
November 16, 2016: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/27838739/sex-differences-in-early-dyspnea-relief-between-men-and-women-hospitalized-for-acute-heart-failure-insights-from-the-relax-ahf-study
#6
Sven Meyer, John R Teerlink, Marco Metra, Piotr Ponikowski, Gad Cotter, Beth A Davison, G Michael Felker, Gerasimos Filippatos, Barry H Greenberg, Tsushung A Hua, Thomas Severin, Min Qian, Adriaan A Voors
AIMS: Women with heart failure are typically older, and more often have hypertension and a preserved left ventricular ejection fraction as compared with men. We sought to analyze if these sex differences influence the course and outcome of acute heart failure. METHODS AND RESULTS: We analyzed sex differences in acute heart failure in 1161 patients enrolled in the RELAX-AHF study. The pre-specified study endpoints were used. At baseline, women (436/1161 patients) were older, had a higher left ventricular ejection fraction, a higher rate of hypertension, and were treated differently from men...
November 12, 2016: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/27832336/comprehensive-endovascular-treatment-of-multiple-arterial-emboli-involving-lima-graft-distal-aorta-and-upper-and-lower-extremities-in-a-patient-with-subacute-cerebral-hemorrhage
#7
LETTER
Nicolas Langwieser, Karl-Ludwig Laugwitz, Tareq Ibrahim
No abstract text is available yet for this article.
November 10, 2016: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/27815638/response-to-prof-dr-med-gunther-wiesner-prof-dr-med-peter-tassani-prell-and-dr-patrick-mayr-deep-sedation-versus-general-anaesthesia-in-percutaneous-edge-to-edge-mitral-valve-reconstruction-using-the-mitraclip-system
#8
LETTER
Suzanne de Waha, Steffen Desch, Ingo Eitel, Holger Thiele
No abstract text is available yet for this article.
November 4, 2016: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/27815637/comment-to-de-waha-s-seeburger-j-et-al-2016-deep-sedation-versus-general-anaesthesia-in-percutaneous-edge-to-edge-mitral-valve-reconstruction-using-the-mitraclip-system-clin-res-cardiol-105-6-535-43
#9
LETTER
Gunther Wiesner, Peter Tassani-Prell, N Patrick Mayr
No abstract text is available yet for this article.
November 4, 2016: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/27766423/the-assessment-of-ischaemic-burden-validation-of-a-functional-jeopardy-score-against-cardiovascular-magnetic-resonance-perfusion-imaging
#10
Shazia T Hussain, Geraint Morton, Kalpa De Silva, Roy Jogiya, Andreas Schuster, Matthias Paul, Divaka Perera, Eike Nagel
AIMS: This study assesses the relationship between classical anatomical jeopardy scores, functional jeopardy scores (combined anatomical and haemodynamic data), and the extent of ischaemia identified on cardiovascular magnetic resonance (CMR) perfusion imaging. METHODS AND RESULTS: In 42 patients with stable angina and suspected coronary artery disease (CAD), CMR perfusion imaging was performed. Fractional Flow Reserve (FFR) was measured in vessels with ≥50 % stenosis...
October 20, 2016: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/27757522/post-dilatation-after-implantation-of-bioresorbable-everolimus-and-novolimus-eluting-scaffolds-an-observational-optical-coherence-tomography-study-of-acute-mechanical-effects
#11
Florian Blachutzik, Niklas Boeder, Jens Wiebe, Alessio Mattesini, Oliver Dörr, Astrid Most, Timm Bauer, Jens Röther, Monique Tröbs, Christian Schlundt, Stephan Achenbach, Christian W Hamm, Holger M Nef
OBJECTIVES: The objective was to investigate the acute mechanical effects of post-dilatation on bioresorbable scaffolds (BRS) as determined by optical coherence tomography (OCT). BACKGROUND: Post-dilatation with high-pressure balloons is regarded as a key component of BRS implantation for treatment of coronary artery stenoses. However, the impact of post-dilatation on BRS in vivo has not been thoroughly investigated. METHODS: OCT was performed after the implantation procedure of 51 everolimus-eluting or novolimus-eluting polylactic acid-based BRS with (n = 27) or without non-compliant balloon post-dilatation (n = 24)...
October 18, 2016: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/27752762/visualization-and-ablation-of-the-autonomic-nervous-system-corresponding-to-ganglionated-plexi-guided-by-d-spect-123-i-mibg-imaging-in-patient-with-paroxysmal-atrial-fibrillation
#12
Alexander Romanov, Stanislav Minin, Christopher Breault, Evgeny Pokushalov
No abstract text is available yet for this article.
October 17, 2016: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/27752761/impact-of-cardiac-comorbidities-on-early-and-1-year-outcome-after-percutaneous-mitral-valve-interventions-data-from-the-german-transcatheter-mitral-valve-interventions-trami-registry
#13
Carsten Schwencke, Klaudija Bijuklic, Taoufik Ouarrak, Edith Lubos, Wolfgang Schillinger, Björn Plicht, Holger Eggebrecht, Stephan Baldus, Gerhard Schymik, Peter Boekstegers, Rainer Hoffmann, Jochen Senges, Joachim Schofer
AIMS: The use of the MitraClip system has gained widespread acceptance for the treatment of patients with mitral regurgitation (MR) who are not suitable for the conventional surgery. This study sought to investigate the early and 1-year outcome after MitraClip therapy of patients with MR and cardiac comorbidities. METHODS AND RESULTS: Outcomes through 12-month follow-up of patients (n = 528) who underwent MitraClip implantation were obtained from the German transcatheter mitral valve interventions (TRAMI) registry...
October 17, 2016: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/27747373/coronary-flow-reserve-in-patients-with-resistant-hypertension
#14
Sebastian Völz, Sara Svedlund, Bert Andersson, Gan Li-Ming, Bengt Rundqvist
Resistant hypertension is associated with increased risk for cardiovascular events. Coronary flow reserve (CFR) is impaired in patients with hypertension and an independent predictor of cardiac mortality. However, there are no published data on CFR in the subset of treatment-resistant hypertension. The aim of this study was to assess CFR in patients with resistant hypertension. Twenty-five consecutive patients with primary resistant hypertension, scheduled for renal denervation, 25 matched patients with controlled hypertension, and 25 healthy controls underwent transthoracic colour Doppler echocardiography at rest and during adenosine infusion...
October 17, 2016: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/27738810/left-ventricular-ejection-fraction-and-presence-of-myocardial-necrosis-assessed-by-cardiac-magnetic-resonance-imaging-correctly-risk-stratify-patients-with-stable-coronary-artery-disease-a-multi-center-all-comers-trial
#15
Dominik Buckert, Sebastian Kelle, Sebastian Buss, Grigorios Korosoglou, Rolf Gebker, Ralf Birkemeyer, Wolfgang Rottbauer, Hugo Katus, Burkert Pieske, Peter Bernhardt
BACKGROUND: Cardiac magnetic resonance imaging (CMR) has become a diagnostic modality that allows for prognostic risk stratification in various cardiac diseases. CMR derived detection of myocardial necrosis by late gadolinium enhancement (LGE) and assessment of left ventricular functional parameters such as left-ventricular ejection fraction (LVEF) have been proven to be significantly associated with outcome and prognosis. Our study focusses on the validation of specific thresholds for these parameters in a multi-center daily all-comers cohort of stable coronary artery disease (CAD) patients...
October 13, 2016: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/27730300/closure-of-coronary-artery-fistula-in-childhood-treatment-techniques-and-long-term-follow-up
#16
Martin Christmann, Ricarda Hoop, Hitendu Dave, Daniel Quandt, Walter Knirsch, Oliver Kretschmar
INTRODUCTION: Coronary artery fistula (CAF) is a rare congenital anomalous connection between the coronary arteries (CA) and a cardiac chamber or great vessel. Treatment options of symptomatic CAF consist of transcatheter or surgical closure. METHODS: Retrospective analysis of all patients with CAF diagnosed between 1993 and 2014 concerning treatment approaches and follow-up after closure. RESULTS: In a cohort of more than 25000 patients, 194 (<0...
October 11, 2016: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/27695989/low-level-exercise-echocardiography-helps-diagnose-early-stage-heart-failure-with-preserved-ejection-fraction-a-study-of-echocardiography-versus-catheterization
#17
Nadjib Hammoudi, Florent Laveau, Gérard Helft, Nathalie Cozic, Olivier Barthelemy, Alexandre Ceccaldi, Thibaut Petroni, Emmanuel Berman, Michel Komajda, Pierre-Louis Michel, Alain Mallet, Claude Le Feuvre, Richard Isnard
BACKGROUND: Increased left ventricular end-diastolic pressure (LVEDP) with exercise is an early sign of heart failure with preserved left ventricular ejection fraction (LVEF). The abnormal exercise increase in LVEDP is nonlinear, with most change occurring at low-level exercise. Data on non-invasive approach of this condition are scarce. Our objective was assessing E/e' to estimate low level exercise LVEDP using a direct invasive measurement as the reference method. METHODS AND RESULTS: Sixty patients with LVEF >50 % prospectively underwent both exercise cardiac catheterization and echocardiography...
September 30, 2016: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/27695988/prognosis-in-patients-with-atrial-fibrillation-and-a-presumed-temporary-cause-in-a-community-based-cohort-study
#18
Laurent Fauchier, Nicolas Clementy, Arnaud Bisson, Karim Stamboul, Fabrice Ivanes, Denis Angoulvant, Dominique Babuty, Gregory Y H Lip
BACKGROUND: Atrial fibrillation (AF) may be related to acute and temporary causes, whether cardiovascular or non-cardiovascular. It remains unclear whether the risk of ischemic stroke is different in this setting, and whether antithrombotic management should be different in these patients. The objective of the study was to describe and compare the risk of stroke in AF patients with and with no such temporary precipitating cause. METHODS: Among 8962 patients with AF seen between 2000 and 2010, we focused our analysis on 4587 patients with non-permanent AF, of whom 740 (16 %) had at least one possible temporary cause of AF...
September 30, 2016: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/27687044/feasibility-and-outcomes-of-interventional-treatment-for-vascular-access-site-complications-following-transfemoral-aortic-valve-implantation
#19
Tim Seidler, Mark Hünlich, Miriam Puls, Gerd Hasenfuß, Claudius Jacobshagen
BACKGROUND: Despite the completion of more than 60,000 transcutaneous aortic valve implantations (TAVI) per year and an approximately 10-15 % incidence of vascular access site complications (VAC), there is a paucity of data on the efficacy and safety of percutaneous VAC treatment. HYPOTHESIS: Percutaneous endovascular treatment will be an effective treatment of VAC and associated with a low rate of surgical repair. Despite stent placement in proximity to the hip joint, endovascular treatment will be only rarely associated with disabling symptoms or complications...
September 29, 2016: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/27670656/procedural-safety-of-a-fully-implantable-intravenous-prostanoid-pump-for-pulmonary-hypertension
#20
Manuel J Richter, Ralf Ewert, Christian Warnke, Henning Gall, Simon Classen, Friedrich Grimminger, Eckhard Mayer, Werner Seeger, Hossein-Ardeschir Ghofrani
BACKGROUND: In patients with severe pulmonary arterial hypertension, subcutaneous or catheter-based intravenous application of prostanoids carries a risk of local side effects or systemic infections, which limits their use and acceptance. Recently, a fully implantable pump for continuous application of intravenous treprostinil was approved in Germany. However, surgery is a major risk for patients with severe pulmonary arterial hypertension. The purpose of this study was to investigate the safety of a fully implantable pump inserted under local or general anesthesia in patients with severe pulmonary hypertension...
September 26, 2016: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
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