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Internal and Emergency Medicine

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https://www.readbyqxmd.com/read/28233161/anemia-is-a-mortality-prognostic-factor-in-patients-initially-hospitalized-for-acute-heart-failure
#1
Margherita Migone de Amicis, David Chivite, Xavier Corbella, Maria Domenica Cappellini, Francesc Formiga
Anemia is a risk factor related to morbidity and mortality in patients with chronic heart failure (HF). Less is known about its influence in patients in an early stage of HF. Our aim is to investigate the prognostic role of anemia in patients initially hospitalized for acute HF. We reviewed all consecutive patients admitted within a 18-month period with a main diagnosis of acute HF. We collected demographic, clinical and treatment data. Anemia is defined as Hemoglobin <12/13 g/dL upon admission in female/male patients, respectively...
February 23, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28210831/cardiac-biomarkers-of-acute-coronary-syndrome-from-history-to-high-sensitive-cardiac-troponin
#2
Mario Plebani, Giorgia Antonelli, Martina Zaninotto
No abstract text is available yet for this article.
February 17, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28197811/an-untreatable-dyspnoea-more-defendants-under-investigation
#3
Alberto Ferrarese, Francesca Bergamo, Fiorella Calabrese, Bruno Girolami, Silvia Iovino, Sara Lonardi, Nazarena Nannini, Stefania Vio, Erika Zola, Andrea Vianello, Giovannella Baggio
No abstract text is available yet for this article.
February 14, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28194697/the-diagnostic-evaluation-of-patients-with-a-suspected-hereditary-periodic-fever-syndrome-experience%C3%A2-from%C3%A2-a-referral-center-in-italy
#4
Antonio Vitale, Donato Rigante, Orso Maria Lucherini, Anna De Palma, Ida Orlando, Stefano Gentileschi, Jurgen Sota, Antonella Simpatico, Claudia Fabiani, Mauro Galeazzi, Bruno Frediani, Luca Cantarini
The study aims are to describe the activity of our Unit on the diagnostics of monogenic autoinflammatory diseases (AIDs), and to apply the clinical classification criteria for periodic fevers from the Eurofever Registry to our cohort of patients, thus evaluating their usefulness in the real life. We retrospectively analyzed data from patients referring to our Center for recurrent fever attacks, and undergoing genetic analysis between April 2014 and July 2016, and we applied the classification criteria to both genetically positive and -negative patients...
February 13, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28194696/parapharyngeal-abscess-with-tracheal-deviation
#5
EDITORIAL
Allison M Yee, Dallin N Christensen, Anna L Waterbrook, Richard Amini
No abstract text is available yet for this article.
February 13, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28194695/real-world-evidence-with-apixaban-for-stroke-prevention-in-patients-with-nonvalvular-atrial-fibrillation-in-germany-a-retrospective-study-reassess
#6
LETTER
Craig Ian Coleman, Matthias Antz
No abstract text is available yet for this article.
February 13, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28191610/italian-intersociety-consensus-on-doac-use-in-internal-medicine
#7
Domenico Prisco, Walter Ageno, Cecilia Becattini, Armando D'Angelo, Giovanni Davì, Raimondo De Cristofaro, Francesco Dentali, Giovanni Di Minno, Anna Falanga, Gualberto Gussoni, Luca Masotti, Gualtiero Palareti, Pasquale Pignatelli, Roberto M Santi, Francesca Santilli, Mauro Silingardi, Antonella Tufano, Francesco Violi
The direct oral anticoagulants (DOACs) are drugs used in clinical practice since 2009 for the prevention of stroke or systemic embolism in non-valvular atrial fibrillation, and for the treatment and secondary prevention of venous thromboembolism. The four DOACs, including the three factor Xa inhibitors (rivaroxaban, apixaban and edoxaban) and one direct thrombin inhibitor (dabigatran) provide oral anticoagulation therapy alternatives to Vitamin K antagonists (VKAs). Despite their clear advantages, the DOACs require on the part of the internist a thorough knowledge of their pharmacokinetic and pharmacodynamic characteristics to ensure their correct use, laboratory monitoring and the appropriate management of adverse events...
February 13, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28191609/complement-blockade-in-anca-associated-vasculitis-an-index-case-current-concepts-and-future-perspectives
#8
REVIEW
Lucio Manenti, Maria Letizia Urban, Federica Maritati, Maricla Galetti, Augusto Vaglio
Complement alternative pathway (cAP) hyperactivation seems to be involved in ANCA-associated vasculitis (AAV). We here describe a case of AAV with severe activation of cAP that developed acute renal failure. No mutation predisposing to cAP dysregulation was identified. We treated our patient with the standard immunosuppressive therapy, but disease progression was only reversed after the addition of eculizumab, a monoclonal antibody against C5; the patient eventually achieved an almost complete renal function recovery...
February 13, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28188579/cardiac-biomarkers-of-acute-coronary-syndrome-from-history-to-high-sensitivity-cardiac-troponin
#9
REVIEW
Pankaj Garg, Paul Morris, Asma Lina Fazlanie, Sethumadhavan Vijayan, Balazs Dancso, Amardeep Ghosh Dastidar, Sven Plein, Christian Mueller, Philip Haaf
The role of cardiac troponins as diagnostic biomarkers of myocardial injury in the context of acute coronary syndrome (ACS) is well established. Since the initial 1st-generation assays, 5th-generation high-sensitivity cardiac troponin (hs-cTn) assays have been developed, and are now widely used. However, its clinical adoption preceded guidelines and even best practice evidence. This review summarizes the history of cardiac biomarkers with particular emphasis on hs-cTn. We aim to provide insights into using hs-cTn as a quantitative marker of cardiomyocyte injury to help in the differential diagnosis of coronary versus non-coronary cardiac diseases...
February 11, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28188578/ultrasound-guided-forearm-nerve-blocks-in-managing-hand-and-finger-injuries
#10
Rebecca Milligan, Stephen Houmes, Lisa C Goldberg, Arun Nagdev, Richard Amini
No abstract text is available yet for this article.
February 10, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28188577/sofa-score-in-septic-patients-incremental-prognostic-value-over-age-comorbidities-and-parameters-of-sepsis-severity
#11
Francesca Innocenti, Camilla Tozzi, Chiara Donnini, Eleonora De Villa, Alberto Conti, Maurizio Zanobetti, Riccardo Pini
Several widely used scoring systems for septic patients have been validated in an ICU setting, and may not be appropriate for other settings like Emergency Departments (ED) or High-Dependency Units (HDU), where a relevant number of these patients are managed. The purpose of this study is to find reliable tools for prognostic assessment of septic patients managed in an ED-HDU. In 742 patients diagnosed with sepsis/severe sepsis/septic shock, not-intubated, admitted in ED between June 2008 and April 2016, SOFA, qSOFA, PIRO, MEWS, Charlson Comorbidity Index, MEDS, and APACHE II were calculated at ED admission (T0); SOFA and MEWS were also calculated after 24 h of ED-High-Dependency Unit stay (T1)...
February 10, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28188576/anti-phospholipid-syndrome-therapy
#12
LETTER
Antonio Ponzetto, Natale Figura, Andrea Caccioppo
No abstract text is available yet for this article.
February 10, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28188575/long-term-oxygen-for-copd-with-moderate-desaturation
#13
Ludovico Furlan, Luca Erba
No abstract text is available yet for this article.
February 10, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28185131/external-validation-of-a-claims-based-and-clinical-approach-for-predicting-post-pulmonary-embolism-outcomes-among-united-states-veterans
#14
Christine G Kohn, Erin R Weeda, Neela Kumar, Philip S Wells, W Frank Peacock, Gregory J Fermann, Li Wang, Onur Baser, Jeff R Schein, Concetta Crivera, Craig I Coleman
The In-hospital Mortality for PulmonAry embolism using Claims daTa (IMPACT) rule can accurately identify pulmonary embolism (PE) patients at low risk of early complications using claims data. We sought to externally validate the IMPACT and simplified Pulmonary Embolism Severity Index (sPESI) tools for predicting all-cause mortality and readmission. We used Veteran Health Administration data (10/1/2010-9/30/2015) to identify adults with ≥1 inpatient diagnosis code for acute PE, ≥12 months continuous medical and pharmacy benefits prior to the index PE, ≥90 days of post-event follow-up (unless death occurred) and ≥1 claim for an anticoagulant during the index PE stay...
February 9, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28181125/different-trajectories-and-significance-of-b-type-natriuretic-peptide-congestion-and-acute-kidney-injury-in-patients-with-heart-failure
#15
Matteo Beltrami, Gaetano Ruocco, Aladino Ibrahim, Barbara Lucani, Beatrice Franci, Ranuccio Nuti, Alberto Palazzuoli
The exact relationship existing among congestion status, brain natriuretic peptide (BNP) changes and acute kidney injury (AKI) has not been elucidated in patients with acute heart failure (AHF). The aims of this study are: to investigate the relation and prognostic role of BNP, AKI and clinical congestion after discharge; to define the exact BNP cut off value or a BNP in-hospital reduction to identify patients with higher risk during vulnerable post-discharge phase. We consecutively enrolled 157 patients with a diagnosis of AHF...
February 8, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28181124/erratum-to-usefulness-of-combining-admission-brain-natriuretic-peptide-bnp-plus-hospital-discharge-bioelectrical-impedance-vector-analysis-biva-in-predicting-90%C3%A2-days-cardiovascular-mortality-in-patients-with-acute-heart-failure
#16
Simona Santarelli, Veronica Russo, Irene Lalle, Benedetta De Berardinis, Silvia Navarin, Laura Magrini, Antonio Piccoli, Marta Codognotto, Luigi Maria Castello, Gian Carlo Avanzi, Humberto Villacorta, Bernardo Luiz Campanário Precht, Pilar Barreto de Araújo Porto, Aline Sterque Villacorta, Salvatore Di Somma
No abstract text is available yet for this article.
February 8, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28181123/noninvasive-ventilation-in-the-emergency-department-insights-on-implementation-bias-and-evidence
#17
LETTER
Mohamad Farouk El-Khatib, Antonio Matias Esquinas, Salah Mahmoud Zeinelddine, Chakib Maurice Ayoub, Pierre Khalil Bou-Khalil
No abstract text is available yet for this article.
February 8, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28181122/association-between-rheumatic-diseases-and-cancer-results-from-a-clinical-practice-cohort-study
#18
Mattia Bellan, Enrico Boggio, Daniele Sola, Antonello Gibbin, Alessandro Gualerzi, Serena Favretto, Giulia Guaschino, Ramona Bonometti, Roberta Pedrazzoli, Mario Pirisi, Pier Paolo Sainaghi
The association between cancer and immune-mediated rheumatic conditions is controversial, especially as far as polymyalgia rheumatica (PMR) is concerned. Furthermore, no clinical feature has been shown to be suggestive of a paraneoplastic rheumatic syndrome. With the present study, we aim to address both these issues. The study population comprised N = 1750 patients, including N = 100 with PMR, who attended our tertiary immuno-rheumatology clinic between January 1, 2005 and November 30, 2012. A rheumatic disease was deemed paraneoplastic if cancer had been diagnosed in the 2 years preceding or following its onset...
February 8, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28176186/ethnic-inequalities-in-acute-myocardial-infarction-hospitalization-rates-among-young-and-middle-aged-adults-in-northern-italy-high-risk-for-south-asians
#19
Ugo Fedeli, Laura Cestari, Eliana Ferroni, Francesco Avossa, Mario Saugo, Pietro Amedeo Modesti
The knowledge of ethnic-specific health needs is now essential to design effective health services and population-based prevention strategies. However, data on migrant populations living in Southern Europe are limited. The study is designed to investigate ethnic inequalities in hospitalization for acute myocardial infarction (AMI) in the Veneto region (Italy). Hospital admissions for AMI in Veneto for the whole resident population aged 20-59 years during 2008-2013 were studied. Age and gender-specific AMI hospitalization rates for immigrant groups (classified by country of origin according to the United Nations geoscheme) and Italians were calculated...
February 7, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28168588/we-have-to-think-before-prescribing-an-opioid-in-italian-emergency-department
#20
LETTER
Bartolomeo Lorenzati, Attilio Allione, Elisa Pizzolato, Luca Dutto, Giuseppe Lauria
No abstract text is available yet for this article.
February 6, 2017: Internal and Emergency Medicine
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