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Internal and Emergency Medicine

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https://www.readbyqxmd.com/read/28929326/the-involvement-of-pharmacies-in-the-screening-of-undiagnosed-atrial-fibrillation
#1
Pietro Amedeo Modesti, Gianni Donigaglia, Plinio Fabiani, Nicola Mumoli, Andrea Colella, Maria Boddi
Early identification of atrial fibrillation (AF) is now a priority in cardiovascular prevention because AF is common although often asymptomatic, and is associated with poor outcomes that are highly preventable with appropriate medical treatment. In Italy, AF prevalence among subjects aged ≥65 years ranges from 5 to 6% in observational studies based on the diagnosis recorded by general practitioners to 10-11% in studies where ECG screening is routinely offered. It is thus evident that a large number of subjects are not detected by conventional approach, and new strategies are required to increase early detection of AF...
September 19, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28929298/chronic-kidney-disease-and-anticoagulation-from-vitamin-k-antagonists-and-heparins-to-direct-oral-anticoagulant-agents
#2
REVIEW
Savino Sciascia, Massimo Radin, Karen Schreiber, Roberta Fenoglio, Simone Baldovino, Dario Roccatello
Anticoagulation in patients with impaired kidney function can be challenging since drugs' pharmacokinetics and bioavailability are altered in this setting. Patients with chronic kidney disease (CKD) treated with conventional anticoagulant agents [vitamin K antagonist (VKA), low-molecular weight heparin (LMWH) or unfractionated heparin (UFH)] are at high risk of bleeding events (both non-major and major clinically relevant bleeding). While anticoagulation reduces the risk of thromboembolic events, the co-existing bleeding risk and the fact that the most commonly used anticoagulation agents are eliminated via the kidneys pose additional challenges...
September 19, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28914417/early-decrease-of-oxidative-stress-by-non-invasive-ventilation-in-patients-with-acute-respiratory-failure
#3
Alessia Garramone, Roberto Cangemi, Emanuela Bresciani, Roberto Carnevale, Simona Bartimoccia, Elisa Fante, Marco Corinti, Marco Brunori, Francesco Violi, Giuliano Bertazzoni, Pasquale Pignatelli
Oxidative stress plays an important role in chronic respiratory diseases where the use of non-invasive ventilation seems to reduce the oxidative damage. Data on acute respiratory failure are still lacking. The aim of the study is to investigate the interplay between oxidative stress and acute respiratory failure, and the role of non-invasive ventilation in this setting. We enrolled 60 patients suffering from acute respiratory failure (PaO2/FiO2 ratio <300): 30 consecutive patients treated with non-invasive ventilation and 30 consecutive patients treated with conventional oxygen therapy...
September 15, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28913788/suboptimal-use-of-statins-for-secondary-cardiovascular-prevention-a-planetary-issue
#4
Alfonso Bellia, David Della-Morte, Davide Lauro
No abstract text is available yet for this article.
September 14, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28913733/a-prospective-feasibility-trial-of-a-novel-intravascular-catheter-system-with-retractable-coiled-tip-guidewire-placed-in-difficult-intravascular-access-diva-patients-in-the-emergency-department
#5
Christopher Raio, Robert Elspermann, Natwalee Kittisarapong, Brendon Stankard, Tanya Bajaj, Veena Modayil, Mathew Nelson, Gerardo Chiricolo, Benjamin Wie, Alexandra Snock, Michael Mackay, Adam Ash
The primary study objective was to evaluate insertion success rates. Secondary objectives included patient satisfaction, procedure time, complication rates, completion of therapy and dwell time of the novel AccuCath(®) 2.25″ Blood Control (BC) Catheter System (FDA approved) placed in difficult-access patients. This was a single-arm feasibility trial evaluating the AccuCath(®) 2.25″ BC Catheter System in a convenience sample of DIVA patients defined as at least two failed initial attempts or a history of difficult access plus the inability to directly visualize or palpate a target vein...
September 14, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28913701/complete-heart-block-during-ultrasound-guided-central-venous-catheterization
#6
EDITORIAL
Iago Jorge, Igor Pietrobom, Aécio Góis
No abstract text is available yet for this article.
September 14, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28900842/early-postictal-serum-lactate-concentrations-are-superior-to-serum-creatine-kinase-concentrations-in-distinguishing-generalized-tonic-clonic-seizures-from-syncopes
#7
Oliver Matz, Jan Heckelmann, Sebastian Zechbauer, Jens Litmathe, Jörg C Brokmann, Klaus Willmes, Jörg B Schulz, Manuel Dafotakis
Concentrations of serum creatine kinase (CK) and serum lactate are frequently measured to help differentiate between generalized tonic-clonic seizures (GTCS) and syncope. The aim of this prospective cohort study was to systematically compare these two markers. The primary outcome is the measurement of serum lactate and CK in blood samples drawn within 2 h of the event in patients admitted with either a GTCS (n = 49) or a syncope (n = 36). Furthermore, the specificity and sensitivity of serum lactate and CK are determined as diagnostic markers in distinguishing between GTCS and syncope...
September 12, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28900817/spleen-dimensions-are-inversely-associated-with-lysosomal-acid-lipase-activity-in-patients-with-non-alcoholic-fatty-liver-disease
#8
Licia Polimeni, Daniele Pastori, Francesco Baratta, Giulia Tozzi, Marta Novo, Roberto Vicinanza, Giovanni Troisi, Gaetano Pannitteri, Fabrizio Ceci, Laura Scardella, Francesco Violi, Francesco Angelico, Maria Del Ben
Fatty liver and splenomegaly are typical features of genetic lysosomal acid lipase (LAL) deficiency. No data in adult patients with non-genetic reduction of LAL activity are available. We investigate the association between spleen dimensions and LAL activity in non-alcoholic fatty liver disease (NAFLD) patients, in whom a reduced LAL activity has been reported. We include 425 consecutive patients who underwent abdominal ultrasound to evaluate hepatic steatosis and spleen dimensions. LAL activity was measured with dried blood spot method (Lalistat2)...
September 12, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28895038/a-retrospective-external-validation-study-of-the-heart-score-among-patients-presenting-to-the-emergency-department-with-chest-pain
#9
Matthew Jay Streitz, Joshua James Oliver, Jessica Marie Hyams, Richard Michael Wood, Yevgeniy Mikhaylovich Maksimenko, Brit Long, Robert Michael Barnwell, Michael David April
Emergency physicians must be able to effectively prognosticate outcomes for patients presenting to the Emergency Department (ED) with chest pain. The HEART score offers a prognostication tool, but external validation studies are limited. We conducted an external retrospective validation study of the HEART score among ED patients presenting to our ED with chest pain from 1 January 2014 to 9 June 2014. We utilized chart review methodology to abstract data from each patient's electronic medical record. We collected data relevant to each of the five elements of the HEART score: history, electrocardiogram (ECG) interpretation, patient age, patient risk factors, and troponin levels...
September 11, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28875298/2d-longitudinal-lv-speckle-tracking-strain-pattern-in-breast-cancer-survivors-sports-activity-vs-exercise-as-prescription-model
#10
Giorgio Galanti, Gianni Pedrizzetti, Stefano Pedri, Laura Stefani
Prevention strategies are important to optimize and to manage heart care in breast cancer survivors. Regular physical activity at moderate intensity is normally proposed to maintain myocardial performance; however, no data is available about the different impact of different levels of physical exercise. 2D speckle tracking echocardiography (2DSTE) is an accepted method for early detection of myocardial dysfunction. The study aims to monitor the cardiac performances in breast cancer survivors by 2DSTE analysis to manage sports activity vs physical activity...
September 5, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28875255/ercp-or-no-ercp-the-case-report-of-a-frail-patient
#11
Vincenzo Occhipinti, Simone Segato, Alberto Carrara, Stefania Orlando, Dario Conte
No abstract text is available yet for this article.
September 5, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28865062/the-fever-of-tommaso-campanella
#12
LETTER
Antonio Perciaccante, Alessia Coralli, Ludovico Abenavoli
No abstract text is available yet for this article.
September 1, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28864910/acute-kidney-injury-and-stroke-unresolved-issues
#13
EDITORIAL
Enrico Fiaccadori, Marco Delsante, Filippo Fani, Giuseppe Regolisti
No abstract text is available yet for this article.
September 1, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28825184/understanding-and-improving-decisions-in-clinical-medicine-ii-making-sense-of-reasoning-in-practice
#14
Fabrizio Elia, Franco Aprà, Vincenzo Crupi
No abstract text is available yet for this article.
August 20, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28819923/severe-dysphagia-rapidly-reverted-after-iron-supplementation
#15
Michele Di Stefano, Elisabetta Pagani, Irene Benedetti, Gino Roberto Corazza
No abstract text is available yet for this article.
August 17, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28815453/the-clinical-eye
#16
Fabrizio Elia, Michele Covella, Mariaelena Perna, Franco Aprà, Vincenzo Crupi
No abstract text is available yet for this article.
August 16, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28815401/abdominal-infection-reveals-a-rare-disease
#17
Clara Benedetta Conti, Mirella Fraquelli, Dario Conte
No abstract text is available yet for this article.
August 16, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28815399/an-aubergine-in-the-heart-huge-native-mitral-valve-endocarditis-caused-by-streptococcus-agalactiae
#18
EDITORIAL
Salvatore Amico, Luigi Calvo, Salvatore Corrao
No abstract text is available yet for this article.
August 16, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28808980/non-invasive-ventilation-in-acute-respiratory-failure-the-key-w-questions
#19
Eliana Margutti, Ilaria Greco, Anna Maria Brambilla, Tommaso Maraffi, Roberto Cosentini
No abstract text is available yet for this article.
August 14, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28808888/has-time-come-for-the-use-of-direct-oral-anticoagulants-in-the-extended-prophylaxis-of-venous-thromboembolism-in-acutely-ill-medical-patients-yes
#20
Walter Ageno
Betrixaban is a direct factor Xa inhibitor with a renal excretion of only approximately 5-7%. On June 23rd 2017, it became the first direct oral anticoagulant to receive Food and Drug Administration approval for the prevention of venous thromboembolism in acutely ill medical patients, and the first anticoagulant agent to be approved for extended-duration thromboprophylaxis after hospital discharge in this setting. Approval followed the results of the APEX trial, a phase III clinical trial comparing betrixaban (80 mg) administered for 35-42 days with enoxaparin (40 mg) administered for 10 ± 4 days...
August 14, 2017: Internal and Emergency Medicine
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