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Journal of Arrhythmia

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https://www.readbyqxmd.com/read/28607624/percutaneous-renal-sympathetic-denervation-in-catecholaminergic-polymorphic-ventricular-tachycardia
#1
Tolga Aksu, Erdem Guler
Catheter-based renal sympathetic denervation may be an alternative after unsuccessful conventional ablation attempts.
June 2017: Journal of Arrhythmia
https://www.readbyqxmd.com/read/28607623/long-rp-interval-tachycardia-what-is-the-mechanism
#2
Javier Jiménez-Díaz, María-Arantzazu González-Marín, Juan J González-Ferrer, Felipe Higuera-Sobrino
A 41-year-old man with a history of tachycardia refractory to multiple antiarrhythmic drugs was sent to our institution. His 12-lead electrocardiogram demonstrated incessant narrow QRS complex tachycardia with negative P waves in the inferior leads and long RP interval. Occasionally, the tachycardia terminated after a P wave and then was restarted after a sinusal beat. An EP study was performed during tachycardia. Intracardiac electrograms during tachycardia and response to pacing maneuvers are shown. What is the tachycardia mechanism?...
June 2017: Journal of Arrhythmia
https://www.readbyqxmd.com/read/28607622/syncope-in-a-patient-with-a-dual-chamber-pacemaker-what-is-the-possible-mechanism
#3
Yavuzer Koza, Ziya Simsek, Selim Aydemir, Remziye Doğan
No abstract text is available yet for this article.
June 2017: Journal of Arrhythmia
https://www.readbyqxmd.com/read/28607621/epicardially-placed-implantable-cardioverter-defibrillator-for-a-child-with-congenital-long-qt-syndrome
#4
Hirotaro Sugiyama, Motomi Tachibana, Hiroshi Morita, Nobuhiro Nishii, Akihito Miyoshi, Hiroyasu Sugiyama, Koji Nakagawa, Atsuyuki Watanabe, Kazufumi Nakamura, Hiroshi Ito
A 7-year-old boy presented at our hospital with syncope. At birth, electrocardiography had shown a long QT interval with torsade de pointes (TdP). Congenital long QT syndrome (LQTS) had been diagnosed by genetic testing, and was successfully controlled with oral propranolol. At age 7, TdP had recurred with syncope. Electrocardiography revealed a prominent long QT interval with T-wave alternans. The propranolol dose was increased, but TdP remained uncontrolled. A cardioverter-defibrillator (ICD) was implanted epicardially, and TdP completely resolved with atrial pacing...
June 2017: Journal of Arrhythmia
https://www.readbyqxmd.com/read/28607620/manifestation-of-j-wave-induced-by-acetylcholine-applied-for-a-coronary-spasm-provocation-test-in-a-patient-with-aborted-sudden-cardiac-death
#5
Hiroyuki Kodama, Kazumasa Fujita, Shouhei Moriyama, Kei Irie, Hirotaka Noda, Taku Yokoyama, Mitsuhiro Fukata, Takeshi Arita, Keita Odashiro, Toru Maruyama, Koichi Akashi
A 51-year-old man with a resuscitation episode was referred to our hospital. Coronary angiography revealed a focal spasm overlapped with organic stenosis where a bare metal stent was implanted. Acetylcholine (ACh) provocation test did not induce chest pain. It revealed no discernible ST-T changes but unmasked a J wave at the end of the QRS complex, which was associated with short-coupled repetitive premature ventricular beats. A J wave reportedly appears immediately before the onset of ventricular fibrillation caused by vasospastic angina...
June 2017: Journal of Arrhythmia
https://www.readbyqxmd.com/read/28607619/molecular-mechanisms-underlying-the-pilsicainide-induced-stabilization-of-herg-proteins-in-transfected-mammalian-cells
#6
Takeshi Onohara, Ichiro Hisatome, Yasutaka Kurata, Peili Li, Tomomi Notsu, Kumi Morikawa, Naoyuki Otani, Akio Yoshida, Kazuhiko Iitsuka, Masaru Kato, Junichiro Miake, Haruaki Ninomiya, Katsumi Higaki, Yasuaki Shirayoshi, Takashi Nishihara, Toshiyuki Itoh, Yoshinobu Nakamura, Motonobu Nishimura
BACKGROUND: Pilsicainide, classified as a relatively selective Na(+) channel blocker, also has an inhibitory action on the rapidly-activating delayed-rectifier K(+) current (IKr ) through human ether-a-go-go-related gene (hERG) channels. We studied the effects of chronic exposure to pilsicainide on the expression of wild-type (WT) hERG proteins and WT-hERG channel currents, as well as on the expression of mutant hERG proteins, in a heterologous expression system. METHODS: HEK293 cells stably expressing WT or mutant hERG proteins were subjected to Western blotting, immunofluorescence microscopy and patch-clamp experiments...
June 2017: Journal of Arrhythmia
https://www.readbyqxmd.com/read/28607618/catechin-and-epicatechin-reduce-mitochondrial-dysfunction-and-oxidative-stress-induced-by-amiodarone-in-human-lung-fibroblasts
#7
Luciana Fernandes Silva Santos, Adriana Stolfo, Caroline Calloni, Mirian Salvador
BACKGROUND: Amiodarone (AMD) and its metabolite N-desethylamiodarone can cause some adverse effects, which include pulmonary toxicity. Some studies suggest that mitochondrial dysfunction and oxidative stress may play a role in these adverse effects. Catechin and epicatechin are recognized as important phenolic compounds with the ability to decrease oxidative stress. Therefore, the aim of this study was to evaluate the potential of catechin and epicatechin to modulate mitochondrial dysfunction and oxidative damage caused by AMD in human lung fibroblast cells (MRC-5)...
June 2017: Journal of Arrhythmia
https://www.readbyqxmd.com/read/28607617/influence-of-myopotential-interference-on-the-wavelet-discrimination-algorithm-in-implantable-cardioverter-defibrillator
#8
Kazuya Mizukami, Hisashi Yokoshiki, Hirofumi Mitsuyama, Masaya Watanabe, Taro Tenma, Rui Kamada, Masayuki Takahashi, Ryo Sasaki, Motoki Maeno, Hiroyuki Tsutsui
BACKGROUND: Wavelet is a morphology-based algorithm for detecting ventricular tachycardia. The electrogram (EGM) source of the Wavelet algorithm is nominally programmed with the Can-RV coil configuration, which records a far-field ventricular potential. Therefore, it may be influenced by myopotential interference. METHODS: We performed a retrospective review of 40 outpatients who had an implantable cardioverter-defibrillator (ICD) with the Wavelet algorithm. The percent-match score of the Wavelet algorithm was measured during the isometric chest press by pressing the palms together...
June 2017: Journal of Arrhythmia
https://www.readbyqxmd.com/read/28607616/a-proposal-of-clinical-ecg-index-vagal-score-for-determining-the-mechanism-of-paroxysmal-atrioventricular-block
#9
Sayaka Komatsu, Masataka Sumiyoshi, Seiji Miura, Yuki Kimura, Tomoyuki Shiozawa, Keiko Hirano, Fuminori Odagiri, Haruna Tabuchi, Hidemori Hayashi, Gaku Sekita, Takashi Tokano, Yuji Nakazato, Hiroyuki Daida
BACKGROUND: Paroxysmal atrioventricular block (P-AVB) is a well-known cause of syncope; however, its underlying mechanism is difficult to determine. This study aimed to evaluate a new ECG index, the "vagal score (VS)," to determine the mechanism of P-AVB. METHODS: We evaluated the VS in 20 patients with P-AVB (13 men, 7 women; aged 25-78 years [mean, 59.3 years]). The VS was developed by assigning 1 point each for the following: (1) no AVB or intraventricular conduction disturbance on the baseline ECG, (2) PR prolongation immediately before P-AVB, (3) sinus slowing immediately before P-AVB, (4) initiation of P-AVB by PP prolongation, (5) sinus slowing during ventricular asystole, and (6) resumption of AV conduction with PP shortening, and by assigning -1 point each for (7) the initiation of P-AVB by a premature beat, and (8) resumption of AV conduction by an escape beat...
June 2017: Journal of Arrhythmia
https://www.readbyqxmd.com/read/28607615/diffuse-interstitial-fibrosis-assessed-by-cardiac-magnetic-resonance-is-associated-with-dispersion-of-ventricular-repolarization-in-patients-with-hypertrophic-cardiomyopathy
#10
David Hurtado-de-Mendoza, Celia P Corona-Villalobos, Iraklis Pozios, Jorge Gonzales, Yalda Soleimanifard, Sanjay Sivalokanathan, Diego Montoya-Cerrillo, Styliani Vakrou, Ihab Kamel, Wilfredo Mormontoy-Laurel, Ketty Dolores-Cerna, Jacsel Suarez, Sergio Perez-Melo, David A Bluemke, Theodore P Abraham, Stefan L Zimmerman, M Roselle Abraham
BACKGROUND: Hypertrophic cardiomyopathy (HCM) is characterized by myocyte hypertrophy, disarray, fibrosis, and increased risk for ventricular arrhythmias. Increased QT dispersion has been reported in patients with HCM, but the underlying mechanisms have not been completely elucidated. In this study, we examined the relationship between diffuse interstitial fibrosis, replacement fibrosis, QTc dispersion and ventricular arrhythmias in patients with HCM. We hypothesized that fibrosis would slow impulse propagation and increase dispersion of ventricular repolarization, resulting in increased QTc dispersion on surface electrocardiogram (ECG) and ventricular arrhythmias...
June 2017: Journal of Arrhythmia
https://www.readbyqxmd.com/read/28607614/pulmonary-vein-potential-mapping-in-atrial-fibrillation-with-high-density-and-standard-spiral-lasso-catheters-a-comparative-study
#11
Axel Meissner, Petra Maagh, Arnd Christoph, Ahmet Oernek, Gunnar Plehn
BACKGROUND: The dominant single-shot procedure for Pulmonary Vein Isolation (PVI) is the Cryoballoon Ablation (CBA) technique using a spiral catheter (Achieve™, AC) for mapping and monitoring purposes. We hypothesized that Basket Catheters, such as the High Density Mesh Mapper (HDMM), with its high-density mapping properties, could detect Pulmonary Vein Potentials (PVPs) that the octapolar AC would not be able to identify. METHODS: Twenty-four patients (average age 61...
June 2017: Journal of Arrhythmia
https://www.readbyqxmd.com/read/28607613/complex-fractionated-atrial-electrograms-high-dominant-frequency-regions-and-left-atrial-voltages-during-sinus-rhythm-and-atrial-fibrillation
#12
Naoko Sasaki, Ichiro Watanabe, Yasuo Okumura, Koichi Nagashima, Rikitake Kogawa, Kazumasa Sonoda, Kazuki Iso, Keiko Takahashi, Masaru Arai, Ryuta Watanabe, Sayaka Kurokawa, Kimie Ohkubo, Toshiko Nakai, Atsushi Hirayama, Mizuki Nikaido
BACKGROUND: Ablation targeting complex fractionated atrial electrograms (CFAEs) or high dominant frequency (DF) sites is generally effective for persistent atrial fibrillation (AF). CFAEs and/or high DF sites may exist in low-voltage regions, which theoretically represent abnormal substrates. However, whether CFAEs or high DF sites reflect low voltage substrates during sinus rhythm (SR) is unknown. METHODS: Sixteen patients with AF (8 with paroxysmal AF; 8, persistent AF) underwent high-density mapping of the left atrium (LA) with a 3-dimensional electroanatomic mapping system before ablation...
June 2017: Journal of Arrhythmia
https://www.readbyqxmd.com/read/28607612/anatomical-dilatation-of-the-superior-vena-cava-associated-with-an-arrhythmogenic-response-induced-by-svc-scan-pacing-after-atrial-fibrillation-ablation
#13
Hiroshi Imada, Koji Fukuzawa, Kunihiko Kiuchi, Akinori Matsumoto, Hiroki Konishi, Hirotoshi Ichibori, Kiyohiro Hyogo, Jun Kurose, Shumpei Mori, Tomofumi Takaya, Tatsuya Nishii, Kiyosumi Kagawa, Akihiro Yoshida, Hirata Ken-Ichi
BACKGROUND: The relationship between pulmonary vein (PV) arrhythmogenicity and its anatomy has been reported. However, that of the superior vena cava (SVC) has not been well discussed. Arrhythmogenic response induced by pacing stimulation at SVC might help with identifying SVC arrhythmogenicity. The purpose of this study was to investigate the relationship between the anatomical dilatation of SVC and the arrhythmogenic response induced by pacing at SVC. METHODS: Forty-three patients who underwent atrial fibrillation (AF) ablation were enrolled in this study...
June 2017: Journal of Arrhythmia
https://www.readbyqxmd.com/read/28607611/report-of-periprocedural-oral-anticoagulants-in-catheter-ablation-for-atrial-fibrillation-the-japanese-catheter-ablation-registry-of-atrial-fibrillation-j-caraf
#14
Yuji Murakawa, Akihiko Nogami, Morio Shoda, Koichi Inoue, Shigeto Naito, Koichiro Kumagai, Yasushi Miyauchi, Teiichi Yamane, Norishige Morita, Hideo Mitamura, Ken Okumura, Kenzo Hirao
BACKGROUND: To obtain a perspective of the current status of catheter ablation for the cure of atrial fibrillation, the Japanese Heart Rhythm Society conducted a nationwide survey: the Japanese Catheter Ablation Registry of Atrial Fibrillation. In this report, we aimed to evaluate the periprocedural use of direct oral anticoagulants with respect to thromboembolic or bleeding complications. METHODS: Using an online questionnaire, the Japanese Heart Rhythm Society requested electrophysiology centers in Japan to register the relevant data of patients who underwent atrial fibrillation ablation over selected five-months from 2011 to 2014...
June 2017: Journal of Arrhythmia
https://www.readbyqxmd.com/read/28607610/remote-magnetic-catheter-navigation-versus-conventional-ablation-in-atrial-fibrillation-ablation-fluoroscopy-reduction
#15
Paul Chun Yih Lim, Joseph Jia Hong Toh, Julian Kenrick Xing Yuan Loh, Edward Chun Yi Lee, Daniel Thuan Tee Chong, Boon Yew Tan, Kah Leng Ho, Chi Keong Ching, Wee Siong Teo
BACKGROUND: Percutaneous transcatheter radiofrequency ablation of atrial fibrillation with remote controlled magnetic navigation (RMN) has been shown to reduce radiation exposure to patients and physicians compared with conventional manual (MAN) ablation techniques. METHODS: Catheter ablation for atrial fibrillation was performed utilizing RMN in 214 consecutive patients and MAN ablation techniques in 229 patients. We compared the fluoroscopy and procedural times between RMN and MAN catheter ablation of atrial fibrillation...
June 2017: Journal of Arrhythmia
https://www.readbyqxmd.com/read/28607609/efficacy-of-ranolazine-in-preventing-atrial-fibrillation-following-cardiac-surgery-results-from-a-meta-analysis
#16
REVIEW
Chintan Trivedi, Ankit Upadhyay, Kinjal Solanki
BACKGROUND: Atrial fibrillation (AF) is a common complication after cardiac surgery. Ranolazine is a Food and Drug Administration approved anti-ischemic drug, which also has anti-arrhythmic properties. Recent studies have demonstrated the benefit of ranolazine in preventing post-operative AF (POAF) in patients undergoing cardiac surgery. Hence, we performed a meta-analysis of published studies comparing ranolazine plus standard therapy versus standard therapy for POAF prevention in patients undergoing cardiac surgery...
June 2017: Journal of Arrhythmia
https://www.readbyqxmd.com/read/28416988/loss-of-atrial-pacing-in-a-patient-with-a-dual-chamber-permanent-pacemaker-what-is-the-mechanism
#17
Enes Elvin Gul, Usama Boles, Fariha Sadiq Ali, Hoshiar Abdollah
No abstract text is available yet for this article.
April 2017: Journal of Arrhythmia
https://www.readbyqxmd.com/read/28416987/importance-of-exercise-testing-shortly-after-subcutaneous-implantable-cardioverter-defibrillator-implantation-in-patients-with-brugada-syndrome-the-first-case-of-associated-inappropriate-shock-in-japan
#18
Kohei Ishibashi, Takashi Noda, Tsukasa Kamakura, Mitsuru Wada, Yuko Inoue, Hideo Okamura, Kengo Kusano
We report the case of a 51-year-old patient with Brugada syndrome (BrS) who experienced inappropriate shock due to T-wave oversensing (TWOS) during exercise when the optimal sensing vector was selected based on the automatic analysis by a subcutaneous implantable cardioverter-defibrillator (S-ICD). After selecting another vector during exercise testing, TWOS did not re-occur. Selection of appropriate sensing vector based on analyses under various conditions, including during exercise after S-ICD implantation, should be considered for patients with BrS...
April 2017: Journal of Arrhythmia
https://www.readbyqxmd.com/read/28416986/two-cases-of-inappropriate-implantable-cardioverter-defibrillator-therapies-due-to-t-wave-oversensing-induced-by-body-twisting
#19
Nobuhiro Nishii, Akihito Miyoshi, Motoki Kubo, Hiroyasu Sugiyama, Motomi Tachibana, Koji Nakagawa, Atsuyuki Watanabe, Hiroshi Morita, Hiroshi Ito
T wave oversensing (TWOS) is a common cause of inappropriate implantable cardioverter-defibrillator (ICD) therapies. Various algorithms to avoid inappropriate ICD therapy are available; however, they are not helpful to avoid TWOS. Although the reproduction of TWOS is useful to resolve the problem of TWOS, it is sometimes difficult to reproduce TWOS. We report two cases of inappropriate ICD therapy due to TWOS, which were induced only by body twisting. We can successfully manage the device based on the evidence of reproduced TWOS...
April 2017: Journal of Arrhythmia
https://www.readbyqxmd.com/read/28416985/successful-pacemaker-lead-extraction-involving-an-ossified-thrombus-a-case-report
#20
Hideo Okamura, John S Van Arnam, Marie Christine Aubry, Paul A Friedman, Yong-Mei Cha
A 41-year-old woman who had been fitted with a pacemaker 18 years prior presented for lead extraction because of device infection. First, we tried laser sheath. However, it cannot cross the binding in the innominate vein. Then we switched to the rotating mechanical sheath. Although it crunched through binding tissue, the progress halted. We removed the sheath and found pieces of calcified tissue in the sheath lumen. After removing the calcified tissue, both leads were extracted using the laser sheath, without complications...
April 2017: Journal of Arrhythmia
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