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Journal of Exposure Science & Environmental Epidemiology

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https://www.readbyqxmd.com/read/29115288/child-environmental-exposures-to-water-and-sand-at-the-beach-findings-from-studies-of-over-68-000-subjects-at-12-beaches
#1
Stephanie DeFlorio-Barker, Benjamin F Arnold, Elizabeth A Sams, Alfred P Dufour, John M Colford, Steven B Weisberg, Kenneth C Schiff, Timothy J Wade
Swimming and recreating in lakes, oceans, and rivers is common, yet the literature suggests children may be at greater risk of illness following such exposures. These effects might be due to differences in immunity or differing behavioral factors such as poorer hygiene, longer exposures to, and greater ingestion of potentially contaminated water and sand. We pooled data from 12 prospective cohorts (n=68,685) to examine exposures to potentially contaminated media such as beach water and sand among children compared with adults, and conducted a simulation using self-reported time spent in the water and volume of water swallowed per minute by age to estimate the total volume of water swallowed per swimming event by age category...
November 8, 2017: Journal of Exposure Science & Environmental Epidemiology
https://www.readbyqxmd.com/read/29115287/consumer-product-chemical-weight-fractions-from-ingredient-lists
#2
Kristin K Isaacs, Katherine A Phillips, Derya Biryol, Kathie L Dionisio, Paul S Price
Assessing human exposures to chemicals in consumer products requires composition information. However, comprehensive composition data for products in commerce are not generally available. Many consumer products have reported ingredient lists that are constructed using specific guidelines. A probabilistic model was developed to estimate quantitative weight fraction (WF) values that are consistent with the rank of an ingredient in the list, the number of reported ingredients, and labeling rules. The model provides the mean, median, and 95% upper and lower confidence limit WFs for ingredients of any rank in lists of any length...
November 8, 2017: Journal of Exposure Science & Environmental Epidemiology
https://www.readbyqxmd.com/read/29064483/coupling-external-with-internal-exposure-metrics-of-trihalomethanes-in-young-females-from-kuwait-and-cyprus
#3
Stephanie Gängler, Konstantinos C Makris, Walid Bouhamra, Douglas W Dockery
The Eastern Mediterranean and the Middle Eastern regions are both understudied in terms of possible environmental health risks for their populations. Water scarcity and desalination treatment provide the general population of countries from these regions (e.g., Kuwait and Cyprus) with unique tap water characteristics. This study investigated the association between external (tap water and 24 h personal air samples) and internal (urine) THM exposure metrics that reflected information about THM-related habits and activities collected using questionnaires and time activity diaries...
October 18, 2017: Journal of Exposure Science & Environmental Epidemiology
https://www.readbyqxmd.com/read/29064482/development-of-a-total-hydrocarbon-ordinal-job-exposure-matrix-for-workers-responding-to-the-deepwater-horizon-disaster-the-gulf-study
#4
Patricia A Stewart, Mark R Stenzel, Gurumurthy Ramachandran, Sudipto Banerjee, Tran B Huynh, Caroline P Groth, Richard K Kwok, Aaron Blair, Lawrence S Engel, Dale P Sandler
The GuLF STUDY is a cohort study investigating the health of workers who responded to the Deepwater Horizon oil spill in the Gulf of Mexico in 2010. The objective of this effort was to develop an ordinal job-exposure matrix (JEM) of airborne total hydrocarbons (THC), dispersants, and particulates to estimate study participants' exposures. Information was collected on participants' spill-related tasks. A JEM of exposure groups (EGs) was developed from tasks and THC air measurements taken during and after the spill using relevant exposure determinants...
October 18, 2017: Journal of Exposure Science & Environmental Epidemiology
https://www.readbyqxmd.com/read/29064481/development-of-a-modeling-approach-to-estimate-indoor-to-outdoor-sulfur-ratios-and-predict-indoor-pm2-5-and-black-carbon-concentrations-for-eastern-massachusetts-households
#5
Chia Hsi Tang, Eric Garshick, Stephanie Grady, Brent Coull, Joel Schwartz, Petros Koutrakis
The effects of indoor air pollution on human health have drawn increasing attention among the scientific community as individuals spend most of their time indoors. However, indoor air sampling is labor-intensive and costly, which limits the ability to study the adverse health effects related to indoor air pollutants. To overcome this challenge, many researchers have attempted to predict indoor exposures based on outdoor pollutant concentrations, home characteristics, and weather parameters. Typically, these models require knowledge of the infiltration factor, which indicates the fraction of ambient particles that penetrates indoors...
October 18, 2017: Journal of Exposure Science & Environmental Epidemiology
https://www.readbyqxmd.com/read/29019346/occupational-exposure-to-pesticides-development-of-a-job-exposure-matrix-for-use-in-population-based-studies-pestipop
#6
Camille Carles, Ghislaine Bouvier, Yolande Esquirol, Camille Pouchieu, Lucile Migault, Clément Piel, Pascale Fabbro-Peray, Séverine Tual, Pierre Lebailly, Isabelle Baldi
Occupational exposure to pesticides concerns a wide population of workers not only in agriculture. The reliability of self-reported information on pesticide use is questionable because of the diversity of use. The PESTIPOP job-exposure matrix has been designed to assess pesticide occupational exposure in the general population. The matrix is composed of two axes: the first axis corresponding to jobs (combinations of occupations and industries) and the second one to pesticide exposure. The estimated exposure metric is the probability of exposure coupled with a reliability assessment (low, medium or high)...
October 11, 2017: Journal of Exposure Science & Environmental Epidemiology
https://www.readbyqxmd.com/read/29019345/suspect-screening-of-maternal-serum-to-identify-new-environmental-chemical-biomonitoring-targets-using-liquid-chromatography-quadrupole-time-of-flight-mass-spectrometry
#7
Roy R Gerona, Jackie M Schwartz, Janet Pan, Matthew M Friesen, Thomas Lin, Tracey J Woodruff
The use and advantages of high-resolution mass spectrometry (MS) as a discovery tool for environmental chemical monitoring has been demonstrated for environmental samples but not for biological samples. We developed a method using liquid chromatography-quadrupole time-of-flight MS (LC-QTOF/MS) for discovery of previously unmeasured environmental chemicals in human serum. Using non-targeted data acquisition (full scan MS analysis) we were able to screen for environmental organic acids (EOAs) in 20 serum samples from second trimester pregnant women...
October 11, 2017: Journal of Exposure Science & Environmental Epidemiology
https://www.readbyqxmd.com/read/28975928/meta-analysis-of-job-exposure-matrix-data-from-multiple-sources
#8
Wenting Cheng, Benjamin Roberts, Bhramar Mukherjee, Richard L Neitzel
The objectives of this study were to determine the heterogeneity of data sources used to construct a job-exposure matrix (JEM) for occupational noise, and to calculate pooled exposure estimates for different job titles using different sources. The JEM was populated with measurements from government databases, private industry, and the published literature. Data were organized by job title using the US standard occupational classification (SOC). Using data from the literature as prior information, adjusted mean exposure was calculated for both the government and industry data following a simple Bayesian approach...
October 4, 2017: Journal of Exposure Science & Environmental Epidemiology
https://www.readbyqxmd.com/read/28975927/quantitative-assessment-of-microbes-from-samples-of-indoor-air-and-dust
#9
Hanna K Leppänen, Martin Täubel, Balamuralikrishna Jayaprakash, Asko Vepsäläinen, Pertti Pasanen, Anne Hyvärinen
Different types of house dust samples are widely used as surrogates of airborne inhalation exposure in studies assessing health effects of indoor microbes. Here we studied-in a quantitative assessment-the representativeness of different house dust samples of indoor air (IA) and investigated seasonality and reproducibility of indoor samples. Microbial exposure was measured five times over 1 year in four rural and five urban Finnish homes. Six sampling methods were used: button inhalable aerosol sampler (actively collected personal and indoor air sampling), settled dust, floor dust, mattress dust and vacuum cleaner dust bag dust; the latter three referred to herein as "reservoir dust samples"...
October 4, 2017: Journal of Exposure Science & Environmental Epidemiology
https://www.readbyqxmd.com/read/28952603/chemical-and-non-chemical-stressors-affecting-childhood-obesity-a-systematic-scoping-review
#10
Kim Lichtveld, Kent Thomas, Nicolle S Tulve
Childhood obesity in the United States has doubled over the last three decades and currently affects 17% of children and adolescents. While much research has focused on individual behaviors impacting obesity, little research has emphasized the complex interactions of numerous chemical and non-chemical stressors found in a child's environment and how these interactions affect a child's health and well-being. The objectives of this systematic scoping review were to (1) identify potential chemical stressors in the context of non-chemical stressors that impact childhood obesity; and, (2) summarize our observations for chemical and non-chemical stressors in regards to child-specific environments within a community setting...
September 27, 2017: Journal of Exposure Science & Environmental Epidemiology
https://www.readbyqxmd.com/read/28930298/comparison-of-questionnaire-based-estimation-of-pesticide-residue-intake-from-fruits-and-vegetables-with-urinary-concentrations-of-pesticide-biomarkers
#11
Yu-Han Chiu, Paige L Williams, Lidia Mínguez-Alarcón, Matthew Gillman, Qi Sun, Maria Ospina, Antonia M Calafat, Russ Hauser, Jorge E Chavarro
We developed a pesticide residue burden score (PRBS) based on a food frequency questionnaire and surveillance data on food pesticide residues to characterize dietary exposure over the past year. In the present study, we evaluated the association of the PRBS with urinary concentrations of pesticide biomarkers. Fruit and vegetable (FV) intake was classified as having high (PRBS≥4) or low (PRBS<4) pesticide residues for 90 men from the EARTH study. Two urine samples per man were analyzed for seven biomarkers of organophosphate and pyrethroid insecticides, and the herbicide 2,4-dichlorophenoxyacetic acid...
September 20, 2017: Journal of Exposure Science & Environmental Epidemiology
https://www.readbyqxmd.com/read/28930297/estimated-radiation-exposure-of-german-commercial-airline-cabin-crew-in-the-years-1960-2003-modeled-using-dose-registry-data-for-2004-2015
#12
Daniel Wollschläger, Gaël Paul Hammer, Thomas Schafft, Steffen Dreger, Maria Blettner, Hajo Zeeb
Exposure to ionizing radiation of cosmic origin is an occupational risk factor in commercial aircrew. In a historic cohort of 26,774 German aircrew, radiation exposure was previously estimated only for cockpit crew using a job-exposure matrix (JEM). Here, a new method for retrospectively estimating cabin crew dose is developed. The German Federal Radiation Registry (SSR) documents individual monthly effective doses for all aircrew. SSR-provided doses on 12,941 aircrew from 2004 to 2015 were used to model cabin crew dose as a function of age, sex, job category, solar activity, and male pilots' dose; the mean annual effective dose was 2...
September 20, 2017: Journal of Exposure Science & Environmental Epidemiology
https://www.readbyqxmd.com/read/28930296/the-verified-neighbor-approach-to-geoprivacy-an-improved-method-for-geographic-masking
#13
Wayne Richter
Geographic information adds a powerful component to environmental epidemiology studies but can compromise subject confidentiality. Although locations are often masked by perturbing spatial coordinates, existing masks do not ensure that the perturbation area contains a sufficient number of valid surrogates to prevent disclosure, nor are they designed to minimize perturbation while maintaining a specified level of privacy. I introduce a new approach to geoprivacy in which real property parcel data with information about land use are used to develop a pool of verified neighbors...
September 20, 2017: Journal of Exposure Science & Environmental Epidemiology
https://www.readbyqxmd.com/read/28901326/environmental-and-biological-monitoring-for-the-identification-of-main-exposure-determinants-in-vineyard-mancozeb-applicators
#14
Stefan Mandic-Rajcevic, Federico M Rubino, Eugenio Ariano, Danilo Cottica, Sara Neri, Claudio Colosio
Grapevine is a vulnerable crop to several fungal diseases often requiring the use of ethylenebisdithiocarbamate (EBDC) fungicides, such as mancozeb. This fungicide has been reported to have goitrogenic, endocrine disrupting, and possibly immunotoxic effects. The aim of this study was to assess workers' exposure in two scenarios of mancozeb application and analyse the main determinants of exposure in order to better understand their mechanism of influence. Environmental monitoring was performed using a modified Organisation for Economic Co-operation and Development (OECD) "patch" methodology and by hand-wash collection, while mancozeb's metabolite, ethylenethiourea (ETU), was measured in 24-h preexposure and postexposure urine samples...
September 13, 2017: Journal of Exposure Science & Environmental Epidemiology
https://www.readbyqxmd.com/read/28975926/one-step-backward-two-steps-forward-science-that-prioritizes-future-generations
#15
EDITORIAL
Elaine A Cohen Hubal
No abstract text is available yet for this article.
November 2017: Journal of Exposure Science & Environmental Epidemiology
https://www.readbyqxmd.com/read/28901325/associations-between-socio-demographic-characteristics-and-chemical-concentrations-contributing-to-cumulative-exposures-in-the-united-states
#16
Hongtai Huang, Rogelio Tornero-Velez, Timothy M Barzyk
Association rule mining (ARM) has been widely used to identify associations between various entities in many fields. Although some studies have utilized it to analyze the relationship between chemicals and human health effects, fewer have used this technique to identify and quantify associations between environmental and social stressors. Socio-demographic variables were generated based on U.S. Census tract-level income, race/ethnicity population percentage, education level, and age information from the 2010-2014, 5-Year Summary files in the American Community Survey (ACS) database, and chemical variables were generated by utilizing the 2011 National-Scale Air Toxics Assessment (NATA) census tract-level air pollutant exposure concentration data...
November 2017: Journal of Exposure Science & Environmental Epidemiology
https://www.readbyqxmd.com/read/28745305/preparation-and-performance-features-of-wristband-samplers-and-considerations-for-chemical-exposure-assessment
#17
Kim A Anderson, Gary L Points, Carey E Donald, Holly M Dixon, Richard P Scott, Glenn Wilson, Lane G Tidwell, Peter D Hoffman, Julie B Herbstman, Steven G O'Connell
Wristbands are increasingly used for assessing personal chemical exposures. Unlike some exposure assessment tools, guidelines for wristbands, such as preparation, applicable chemicals, and transport and storage logistics, are lacking. We tested the wristband's capacity to capture and retain 148 chemicals including polychlorinated biphenyls (PCBs), pesticides, flame retardants, polycyclic aromatic hydrocarbons (PAHs), and volatile organic chemicals (VOCs). The chemicals span a wide range of physical-chemical properties, with log octanol-air partitioning coefficients from 2...
November 2017: Journal of Exposure Science & Environmental Epidemiology
https://www.readbyqxmd.com/read/28745304/multi-class-chemical-exposure-in-rural-peru-using-silicone-wristbands
#18
Alan J Bergmann, Paula E North, Luis Vasquez, Hernan Bello, Maria Del Carmen Gastañaga Ruiz, Kim A Anderson
Exposure monitoring with personal silicone wristband samplers was demonstrated in Peru in four agriculture and urban communities where logistic and practical constraints hinder use of more traditional approaches. Wristbands and associated methods enabled quantitation of 63 pesticides and screening for 1397 chemicals including environmental contaminants and personal care products. Sixty-eight wristbands were worn for approximately one month by volunteers from four communities of Alto Mayo, Peru. We identified 106 chemicals from eight chemical classes among all wristbands...
November 2017: Journal of Exposure Science & Environmental Epidemiology
https://www.readbyqxmd.com/read/28120831/integrating-data-from-multiple-time-location-measurement-methods-for-use-in-exposure-assessment-the-multi-ethnic-study-of-atherosclerosis-and-air-pollution-mesa-air
#19
Marnie F Hazlehurst, Elizabeth W Spalt, Cynthia L Curl, Mark E Davey, Sverre Vedal, Gregory L Burke, Joel D Kaufman
Tools to assess time-location patterns related to environmental exposures have expanded from reliance on time-location diaries (TLDs) and questionnaires to use of geospatial location devices such as data-logging Global Positioning System (GPS) equipment. The Multi-Ethnic Study of Atherosclerosis and Air Pollution obtained typical time-location patterns via questionnaire for 6424 adults in six US cities. At a later time (mean 4.6 years after questionnaire), a subset (n=128) participated in high-resolution data collection for specific 2-week periods resulting in concurrent GPS and detailed TLD data, which were aggregated to estimate time spent in various microenvironments...
November 2017: Journal of Exposure Science & Environmental Epidemiology
https://www.readbyqxmd.com/read/27924817/in-vitro-human-epidermal-permeation-of-nicotine-from-electronic-cigarette-refill-liquids-and-implications-for-dermal-exposure-assessment
#20
H Frederick Frasch, Ana M Barbero
Nicotine plus flavorings in a propylene glycol (PG) vehicle are the components of electronic cigarette liquids (e-liquids), which are vaporized and inhaled by the user. Dermal exposure to nicotine and e-liquids may occur among workers in mixing and filling of e-cigarettes in the manufacturing process. Inadvertent skin contact among consumers is also a concern. In vitro nicotine permeation studies using heat-separated human epidermis were performed with surrogate and two commercial e-liquids, neat and aqueous nicotine donor formulations...
November 2017: Journal of Exposure Science & Environmental Epidemiology
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