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Journal of Exposure Science & Environmental Epidemiology

Benjamin D Blair, Stephen Brindley, Eero Dinkeloo, Lisa M McKenzie, John L Adgate
Public concern about oil and gas (O&G) operations in residential areas is substantial. Noise from construction and drilling related to O&G operations may be greater than other phases of O&G operations; yet the impacts of audible and low-frequency noise during these operations are not extensively explored nor the effects on health well understood. This study documents the noise levels at a multi-well O&G well pad during construction and drilling in a residential area in Colorado. A-weighted (dBA) and C-weighted (dBC) noise measurements were collected at four locations during development over a 3-month period...
May 11, 2018: Journal of Exposure Science & Environmental Epidemiology
Hualiang Lin, Jun Tao, Haidong Kan, Zhengmin Qian, Ailan Chen, Yaodong Du, Tao Liu, Yonghui Zhang, Yongqing Qi, Jianjun Ye, Shuangming Li, Wanglin Li, Jianpeng Xiao, Weilin Zeng, Xing Li, Katherine A Stamatakis, Xinyu Chen, Wenjun Ma
Limited evidence exists concerning the impact of particulate pollution on acute respiratory distress syndrome (ARDS). We examined the effects of particulate pollution on emergency ambulance dispatches (EAD) for ARDS in Guangzhou, China. Daily air pollution concentrations for PM10 , PM2.5 , and PM1 , as well as PM2.5 chemical compositions, were available from a central air monitoring station. The association between incident ARDS and air pollution on the concurrent and previous 5 days was estimated by an over-dispersed Poisson generalized additive model controlling for meteorological factors, temporal trends, public holidays and day of the week...
April 30, 2018: Journal of Exposure Science & Environmental Epidemiology
Aaron J Specht, Marc Weisskopf, Linda H Nie
Childhood lead exposure has been shown to have a significant effect on neurodevelopment. Many of the biokinetics involved with lead biomarkers in children still remain unknown. Two hundred fifty (157 in the exposed group and 93 controls) children were enrolled in our study and lead exposed children returned for multiple visits for measurement of blood and bone lead and chelation treatment. We demonstrated that the correlation between blood and bone lead increased with subsequent visits. We calculated the blood lead half-life for 50 patients, and found a significant (p-value < 0...
April 30, 2018: Journal of Exposure Science & Environmental Epidemiology
M M Nyhan, I Kloog, R Britter, C Ratti, P Koutrakis
A critical question in environmental epidemiology is whether air pollution exposures of large populations can be refined using individual mobile-device-based mobility patterns. Cellular network data has become an essential tool for understanding the movements of human populations. As such, through inferring the daily home and work locations of 407,435 mobile phone users whose positions are determined, we assess exposure to PM2.5 . Spatiotemporal PM2.5 concentrations are predicted using an Aerosol Optical Depth- and Land Use Regression-combined model...
April 27, 2018: Journal of Exposure Science & Environmental Epidemiology
Alexis Donohue, Carol L Wagner, James B Burch, Sarah E Rothenberg
BACKGROUND: Maternal blood total mercury (THg) is a biomarker for prenatal methylmercury (MeHg) exposure. Few studies have quantified both blood THg and MeHg during pregnancy, and few studies have reported longitudinal trends. OBJECTIVES: We analyzed blood THg and MeHg in a cohort of pregnant mothers in Charleston, South Carolina (n = 83), and investigated whether blood THg or MeHg changed between early and late gestation. METHODS: THg and MeHg were analyzed in blood samples from early (12 ± 1...
April 19, 2018: Journal of Exposure Science & Environmental Epidemiology
William C Griffith, Eric M Vigoren, Marissa N Smith, Tomomi Workman, Beti Thompson, Gloria D Coronado, Elaine M Faustman
The take-home pathway is a significant source of organophosphate pesticide exposure for young children (3-5 years old) living with an adult farmworker. This avoidable exposure pathway is an important target for intervention. We selected 24 agricultural communities in the Yakima Valley of Washington State and randomly assigned them to receive an educational intervention (n = 12) to reduce children's pesticide exposure or usual care (n = 12). We assessed exposure to pesticides in nearly 200 adults and children during the pre and post-intervention periods by measuring metabolites in urine...
April 17, 2018: Journal of Exposure Science & Environmental Epidemiology
Z Awada, F Sleiman, A Mailhac, Y Mouneimne, H Tamim, N K Zgheib
The aim of this study was to evaluate the potential association of urinary Bisphenol A (BPA) levels with estrogen receptor alpha (ESR1) promoter % methylation and relative telomere length in a sample of 482 participants. Urinary BPA concentration was measured using organic phase extraction followed by high performance liquid chromatography mass spectroscopy. Peripheral blood ESR1 promoter % methylation and relative telomere length were measured using direct bisulfite sequencing and real-time polymerase chain reaction, respectively...
April 12, 2018: Journal of Exposure Science & Environmental Epidemiology
Kaitlin Kelly-Reif, David B Richardson, Steve Wing
Environmental radiation releases from a nuclear fuel fabrication facility in Apollo, Pennsylvania may have exposed the surrounding population to ionizing radiation. This study characterizes cancer incidence in the population living near the nuclear facility between 1990 and 2010. Cancer incidence in the minor civil divisions surrounding the Apollo facility was compared to a standard population of the state of Pennsylvania adjusted for calendar year, age, sex, and race. Bias due to residential misclassification was considered by adjustment of case count...
April 5, 2018: Journal of Exposure Science & Environmental Epidemiology
Whitney J Cowell, Andreas Sjödin, Richard Jones, Ya Wang, Shuang Wang, Julie B Herbstman
Polybrominated diphenyl ethers (PBDEs) were used extensively as flame retardants in furniture containing polyurethane foam until they were phased out of use, beginning in 2004. We examined temporal changes in plasma PBDE concentrations from 1998 to 2013 and characterized patterns of exposure over the early lifecourse among 334 children (903 samples) between birth and 9 years. We examined time trends by regressing PBDE concentration on year of sample collection in age-adjusted models and characterized developmental trajectories using latent class growth analysis (LCGA)...
April 4, 2018: Journal of Exposure Science & Environmental Epidemiology
Susanna D Mitro, MyDzung T Chu, Robin E Dodson, Gary Adamkiewicz, Lucy Chie, Florence M Brown, Tamarra M James-Todd
Phthalates exposure has been linked to multiple health risks, and US immigrants may have different exposures to phthalates due to lifestyle differences. Urinary concentrations of eight phthalate metabolites (mono-ethyl phthalate [MEP], mono-n-butyl phthalate [MnBP], mono-isobutyl phthalate [MiBP], mono-(3-carboxypropyl) phthalate [MCPP], mono-benzyl phthalate [MBzP], mono-2-ethylhexyl phthalate [MEHP], mono-(2-ethyl-5-hydroxyhexyl) phthalate [MEHHP], mono-(2-ethyl-5-oxohexyl) phthalate [MEOHP]) were measured in 10318 US-born and 3511 foreign-born individuals from NHANES 1999-2014...
March 23, 2018: Journal of Exposure Science & Environmental Epidemiology
Christopher D Zevitas, John D Spengler, Byron Jones, Eileen McNeely, Brent Coull, Xiaodong Cao, Sin Ming Loo, Anna-Kate Hard, Joseph G Allen
OBJECTIVE: To measure sound levels in the aircraft cabin during different phases of flight. METHODS: Sound level was measured on 200 flights, representing six aircraft groups using continuous monitors. A linear mixed-effects model with random intercept was used to test for significant differences in mean sound level by aircraft model and across each flight phase as well as by flight phase, airplane type, measurement location and proximity to engine noise. RESULTS: Mean sound levels across all flight phases and aircraft groups ranged from 37...
March 15, 2018: Journal of Exposure Science & Environmental Epidemiology
Michelle L Bell, Geetanjoli Banerjee, Gavin Pereira
Health studies on spatially-varying exposures (e.g., air pollution) during pregnancy often estimate exposure using residence at birth, disregarding residential mobility. We investigated moving patterns in pregnant women (n = 10,116) in linked cohorts focused on Connecticut and Massachusetts, U.S., 1988-2008. Moving patterns were assessed by race/ethnicity, age, marital status, education, working status, population density, parity, income, and season of birth. In this population, 11.6% of women moved during pregnancy...
March 6, 2018: Journal of Exposure Science & Environmental Epidemiology
Marnie F Hazlehurst, Elizabeth W Spalt, Tyler P Nicholas, Cynthia L Curl, Mark E Davey, Gregory L Burke, Karol E Watson, Sverre Vedal, Joel D Kaufman
Exposure estimates that do not account for time in-transit may underestimate exposure to traffic-related air pollution, but exact contributions have not been studied directly. We conducted a 2-week monitoring, including novel in-vehicle sampling, in a subset of the Multi-Ethnic Study of Atherosclerosis and Air Pollution cohort in two cities. Participants spent the majority of their time indoors and only 4.4% of their time (63 min/day) in-vehicle, on average. The mean ambient-source NO2 concentration was 5...
March 6, 2018: Journal of Exposure Science & Environmental Epidemiology
Xiao Zhang, Xiaohui Xu, Yan Zhong, Melinda C Power, Brandie D Taylor, Genny Carrillo
Arsenic is a prevalent environmental contaminant, and its folate-dependent methylation is important for detoxification in the body. In this study, we investigated the association between serum folate levels and methylation using data from the US National Health and Nutrition Examination Survey (NHANES) (2003-2012) (N = 11,016). Multivariate linear regression and penalized spline regression models were used to examine the association and possible upper limit of folate level regarding its impact on methylation in children (≤18 years) and adults (>18 years), respectively...
February 26, 2018: Journal of Exposure Science & Environmental Epidemiology
Huan Shu, Bo Ag Jönsson, Chris Gennings, Åke Svensson, Eewa Nånberg, Christian H Lindh, Malin Knutz, Tim K Takaro, Carl-Gustaf Bornehag
BACKGROUND: The general population is exposed to phthalates, a group of chemicals with strong evidence for endocrine disrupting properties, commonly used in a large number of consumer products. Based on published research and evidence compiled by environmental agencies, certain phthalate applications and products have become restricted, leading to an increasing number of "new generation compounds" coming onto the market during recent years replacing older phthalates. Some examples of such newer compounds are di-iso-nonyl phthalate (DiNP), di-iso-decyl phthalate (DiDP), and most recently di-isononyl-cyclohexane-1,2-dicarboxylate (DiNCH)...
February 22, 2018: Journal of Exposure Science & Environmental Epidemiology
Gyeong-Hun Park, Chanhee Nam, Seungphil Hong, Byungcheol Park, Hakrim Kim, Taewon Lee, Kyubong Kim, Jong Hee Lee, Myung Hwa Kim
Despite daily exposure to chemicals in cosmetic products, there are few studies on the exposure levels to cosmetics particularly in Asians. We sought to investigate the usage pattern of cosmetics, including eye makeup products, fragrances, color makeups, and hair and nail care products, in Koreans. An online survey of 1,800 participants (908 males and 892 females, aged 15-59 years) from 5 Metropolitan cities (Seoul, Incheon, Daejeon, Daegu, and Busan) in Korea was conducted. For overall types of cosmetics, the proportion of users was 7...
May 2018: Journal of Exposure Science & Environmental Epidemiology
Scott M Bartell
This corrects the article DOI: 10.1038/jes.2012.2.
May 2018: Journal of Exposure Science & Environmental Epidemiology
Wenjing Li, Yang Cao, Runkui Li, Xinming Ma, Jieying Chen, Zhenglai Wu, Qun Xu
Owing to lack of data from multiple air quality monitoring stations, studies about spatial association between concentrations of ambient pollutants and mortality in China are rare. To investigate the spatial variation of association between concentrations of particulate matter less than 10 μm in aerodynamic diameter (PM10 ), nitrogen dioxide (NO2 ) and carbon monoxide (CO) and cardiovascular mortality in Beijing, China, we collected data including daily deaths, concentrations of PM10 , NO2 and CO, and meteorological factors from 1 January 2009 to 31 December 2010 in all 16 districts of Beijing...
May 2018: Journal of Exposure Science & Environmental Epidemiology
Stephanie DeFlorio-Barker, Benjamin F Arnold, Elizabeth A Sams, Alfred P Dufour, John M Colford, Steven B Weisberg, Kenneth C Schiff, Timothy J Wade
Swimming and recreating in lakes, oceans, and rivers is common, yet the literature suggests children may be at greater risk of illness following such exposures. These effects might be due to differences in immunity or differing behavioral factors such as poorer hygiene, longer exposures to, and greater ingestion of potentially contaminated water and sand. We pooled data from 12 prospective cohorts (n=68,685) to examine exposures to potentially contaminated media such as beach water and sand among children compared with adults, and conducted a simulation using self-reported time spent in the water and volume of water swallowed per minute by age to estimate the total volume of water swallowed per swimming event by age category...
March 2018: Journal of Exposure Science & Environmental Epidemiology
Stephanie Gängler, Konstantinos C Makris, Walid Bouhamra, Douglas W Dockery
The Eastern Mediterranean and the Middle Eastern regions are both understudied in terms of possible environmental health risks for their populations. Water scarcity and desalination treatment provide the general population of countries from these regions (e.g., Kuwait and Cyprus) with unique tap water characteristics. This study investigated the association between external (tap water and 24 h personal air samples) and internal (urine) THM exposure metrics that reflected information about THM-related habits and activities collected using questionnaires and time activity diaries...
March 2018: Journal of Exposure Science & Environmental Epidemiology
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