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Journal of Burn Care & Research: Official Publication of the American Burn Association

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https://www.readbyqxmd.com/read/30376104/impact-of-burn-related-amputations-on-return-to-work-findings-from-the-burn-injury-model-system-national-database
#1
Gretchen J Carrougher, Kara McMullen, Samuel P Mandell, Dagmar Amtmann, Karen J Kowalske, Jeffrey C Schneider, David N Herndon, Nicole S Gibran
Amputations following a burn injury, although infrequent, may impact community re-integration and create a barrier to returning to work. The objective of this study was to compare patient and injury characteristics, quality of life, and employment status for those with and without amputation using a national longitudinal database of people with burn injuries. In this retrospective review of prospectively collected data group differences were examined using descriptive statistics. We used linear and logistic regression models to identify factors significantly associated with amputation, factors associated with return to work rates, and SF-12 Physical (PCS) and Mental (MCS) Component Summary scores over time...
October 29, 2018: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/30371792/the-use-of-a-brief-measure-to-assess-longitudinal-changes-in-appearance-concerns-for-youth-recovering-from-burn-injuries
#2
Valerie F Weed, Katia Canenguez, Stephanie Romo, Shirley L Wang, Lewis Kazis, Austin F Lee, David Herndon, Tina L Palmieri, Petra Warner, Haregnesh Haile, Robert L Sheridan, J Michael Murphy
Burns are among the most common injuries to children and, although survival rates have improved, many burn survivors are left with scars and/or other visible differences, which may be associated with anxiety, depression, and/or low self-esteem. A better understanding of the prevalence and persistence of these problems in child and adolescent burn survivors might lead to an expanded paradigm of care and possibly to better outcomes. The current study provides longitudinal prevalence data for the Appearance Concerns (AC) subscale of the parent-reported Burn Outcomes Questionnaire for 5-18 year olds and identifies patient characteristics associated with higher risk for appearance concerns...
October 29, 2018: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/30371861/identification-of-cytochrome-p450-polymorphisms-in-burn-patients-and-impact-on-fentanyl-pharmacokinetics-a-pilot-study
#3
Kristin N Grimsrud, Xenia Ivanova, Catherine M Sherwin, Tina L Palmieri, Nam K Tran
Pain management is critical for burn care. Unfortunately, inter-individual variation in pharmacokinetics (PK) due to burn hypermetabolism and genetic polymorphisms can lead to treatment failures in this at-risk population. Aanalgesics may be affected by genetic polymorphisms affecting cytochrome P450 (CYP) drug metabolizing enzymes. Fentanyl is a common opiate primarily metabolized by CYP3A4 subtypes. Recent studies demonstrate CYP2D6 variants impacting fentanyl pharmacokinetics (PK). Functional CYP polymorphisms can significantly alter opiate levels resulting in inadequate analgesia or life-threatening toxicity...
October 27, 2018: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/30371857/the-frequency-and-reason-for-amputations-in-electrically-burned-pediatric-patients
#4
Christian Tapking, Gabriel Hundeshagen, Daniel Popp, Jong O Lee, David N Herndon, Ramón Zapata-Sirvent, Ludwik K Branski
Electrical injuries induce substantial morbidity and mortality. Amputations are often necessary to enable survival and based on tissue non-viability, development of life threatening infection or expected non-functional outcome. We analyzed occurrence and type of amputations in our institution for electrical and non-electrical pediatric burns and the number of reconstructive operations. Patients who underwent any amputation between 1999 and 2017 were identified. Patients with electrical burns (EB) were matched regarding age, sex and percent total body surface area (%TBSA) burned to patients with non-electrical burns (NEB)...
October 27, 2018: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/30365029/the-clinical-significance-of-serum-1-3-%C3%AE-d-glucan-for-the-diagnosis-of-candidemia-in-severe-burn-patients
#5
Yasuhiko Kaita, Takehiko Tarui, Akiyasu Otsu, Yuya Tanaka, Jun Suzuki, Kei Yoshikawa, Yoshihiro Yamaguchi
No abstract text is available yet for this article.
October 25, 2018: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/30351404/current-trends-in-practice-for-early-mobility-with-the-burn-population
#6
Ingrid Parry, Soman Sen, Tina Palmieri, David Greenhalgh
There is a clinical trend toward "early mobilization" of patients with burn injury, however mobility is not well defined in burn care. Burn injuries result in various extents of injury, body areas affected, and types of skin graft surgeries needed-all of which may influence the type, timing, safety, and outcome of mobilization activities. This study surveyed burn clinicians to determine current mobility practices and the influence of skin graft surgery on clinical decisions to mobilize patients. A 32-question survey was electronically distributed to burn clinicians and included questions about postoperative range of motion (ROM) and out of bed (OOB) mobility practices for various skin graft types and locations...
October 22, 2018: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/30247668/parent-distress-following-pediatric-burn-injuries
#7
Carisa Parrish, Ashley Shields, Adam Morris, Anna George, Elizabeth Reynolds, Lindsay Borden, Jessica Hankinson, Susan Ziegfeld, Dylan Stewart, Rick Ostrander
Objective: Parents commonly report elevated distress following a child's burn injury, yet limited research has identified child or injury characteristics that may explain parent distress. The main goal of the current study is to examine prevalence and predictors of parent distress following children's burn injuries by evaluating distress symptoms in a clinic sample of parents whose children present for evaluation and treatment at a regional burn center. Methods: Participants included parents of 407 children who experienced a burn injury...
September 22, 2018: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/30247616/a-mixed-methods-investigation-into-the-acceptability-usability-and-perceived-effectiveness-of-active-and-passive-virtual-reality-scenarios-in-managing-pain-under-experimental-conditions
#8
Ivan Phelan, Penny J Furness, Orla Fehily, Andrew R Thompson, Nathan T Babiker, Martin A Lamb, Shirley A Lindley
Burns patients often suffer excruciating pain during clinical procedures, even with analgesia. Virtual Reality as an adjunct to pharmacological therapy has proved promising in the management of burn pain. More evidence is needed regarding specific forms of Virtual Reality. This mixed-method study examined the impact of active and passive Virtual Reality scenarios in experimental conditions, gathering data relating to user experience, acceptability and effectiveness in managing pain. Four scenarios were developed or selected following a consultative workshop with burns survivors and clinicians...
September 21, 2018: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/30247564/cardiovascular-effect-of-varying-interval-training-frequency-in-rehabilitation-of-severely-burned-children
#9
Christian Tapking, Daniel Popp, David N Herndon, Andrew M Armenta, Ludwik K Branski, Andrew J Murton, Oscar E Suman
Structured exercise programs initiated after acute hospitalization can improve muscle strength and mass, cardiorespiratory capacity, and quality of life in severely burned children. In this retrospective study, we compared the cardiovascular effects of an exercise program incorporating a large number of interval training sessions with a traditional exercise program incorporating a small number of interval training sessions. Severely burned children who completed a large number of sessions (≥3 sessions per week, N=40) were matched to those completing a small number of sessions (≤2 sessions per week, N=40)...
September 21, 2018: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/30247559/changing-the-way-we-think-about-burn-size-estimation
#10
Christopher Pham, Zachary Collier, Justin Gillenwater
Background: Burn size estimation is a crucial component of acute burn management that guides referral to burn centers, fluid resuscitation parameters, hospital resource distribution, and mortality-based interventions. Referring providers often misestimate the total body surface area (TBSA) of burn injury, which contributes to unnecessary healthcare costs, misappropriation of limited resources, and delay in provision of appropriate patient care. Methods: A systematic literature review of articles available on PubMed, Scopus, Google Scholar, OvidSP Medline, and Web of Science was performed...
September 21, 2018: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/30239737/burn-patients-perceptions-of-their-care-what-can-we-learn-from-post-discharge-satisfaction-surveys
#11
Andrea Dai, Megan Moore, Anna Polyakovsky, Tracy Gooding, Tara Lerew, Gretchen J Carrougher, Nicole S Gibran, Tam N Pham
Introduction: Little is understood about the inpatient experience from the burn patients' perspectives. Rather, hospitals emphasize quantitative feedback as part of the ongoing process improvement. Comments returned with the Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) administrative survey may provide important patient perspectives. We analyzed quantitative and qualitative HCAHPS data to identify areas for care improvement. Methods: We reviewed our burn center HCAHPS results over 2 years...
September 18, 2018: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/30202971/contemplating-a-career-in-burn-surgery-data-from-the-2016-burn-physician-survey
#12
L S Johnson, M H Jordan, J W Shupp
There is a paucity of information in the peer-reviewed literature characterizing the current burn surgeon workforce and compensation potential, and, in a parallel topic, training opportunities and recruitment methods. What does exist documents minimal exposure to the field and surgeon shortages. A comprehensive survey was created to address 1) the demographics of current burn surgeons in practice, and 2) the structure of burn centers training models. Finally, three questions were asked regarding job satisfaction...
September 7, 2018: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/30189043/acute-kidney-injury-after-burn-a-cohort-study-from-the-parkland-burn-intensive-care-unit
#13
Audra T Clark, Xilong Li, Rohan Kulangara, Beverley Adams-Huet, Sarah C Huen, Tarik D Madni, Jonathan B Imran, Herb A Phelan, Brett D Arnoldo, Orson W Moe, Steven E Wolf, Javier A Neyra
Rationale & Objective: Acute kidney injury (AKI) is a common and morbid complication in patients with severe burn. The reported incidence of AKI and mortality in this population vary widely due to inconsistent and changing definitions. We aimed to examine the incidence, severity, and hospital mortality of AKI patients after burn using consensus criteria. Study Design: Retrospective cohort study of adults with thermal injury admitted to the Parkland burn intensive care unit (ICU) from 2008 to 2015...
September 5, 2018: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/30189005/pigmentation-diathesis-of-hypertrophic-scar-an-examination-of-known-signaling-pathways-to-elucidate-the-molecular-pathophysiology-of-injury-related-dyschromia
#14
Bonnie C Carney, Jason H Chen, Jenna N Luker, Abdulnaser Alkhalil, Daniel Y Jo, Taryn E Travis, Lauren T Moffatt, Cynthia M Simbulan-Rosenthal, Dean S Rosenthal, Jeffrey W Shupp
Hypertrophic scar (HTS) occurs frequently after burn injury. Treatments for some aspects of scar morbidity exist, however, dyspigmentation treatments are lacking due to limited knowledge about why scars display dyschromic phenotypes. Full thickness wounds were created on duroc pigs that healed to form dyschromic HTS. HTS biopsies and primary cell cultures were then used to study pigmentation signaling. Biopsies of areas of both pigment types were taken for analysis. At the end of the experiment, melanocyte-keratinocyte co-cultures were established from areas of differential pigmentation...
September 5, 2018: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/30189001/intravenous-ketamine-as-an-adjunct-to-procedural-sedation-during-burn-wound-care-and-dressing-changes
#15
Phillip G Brennan, James K Landry, M Victoria P Miles, Alicia C Lintner, Kaitlin A McGinn, Steven A Kahn
Little has been published regarding intravenous (IV) ketamine for burn wound care in adult patients. Ketamine may serve as a safe alternative to provide conscious sedation and limit opioid administration to patients. The purpose of this study was to characterize IV ketamine use during burn wound care and establish its potential role as a safe adjunct to opioid and benzodiazepine medications. This is a retrospective review of adult patients admitted to a regional burn center who received IV ketamine for burn wound care...
September 5, 2018: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/30165665/a-successful-limb-salvage-of-an-electrical-burned-patient-with-extensive-soft-tissue-and-femoral-bone-necrosis
#16
Hui Chen, Zhong Chen, Jie Wang, Peng Tian, Yu-Ming Shen, Lei Huang, Xiao-Hua Hu
Severe electrical injury presents a formidable therapeutic challenge for surgeons because of the requirement for complex soft tissue and bony reconstruction to restore functionality of the injured area. The authors report on the limb salvage procedure for a patient with extensive soft tissue and femoral bone necrosis from a high-voltage electrical burn. The right thigh and knee were burned, resulting in large areas of muscle necrosis and a long segment of distal femur exposure and necrosis. Complete debridement of the area resulted in a 20 × 35 cm soft tissue defect and an 18-cm long distal femoral bone defect...
August 28, 2018: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/30137429/development-of-pseudomonas-aeruginosa-biofilms-in-partial-thickness-burn-wounds-using-a-sprague-dawley-rat-model
#17
Kenneth S Brandenburg, Alan J Weaver, Liwu Qian, Tao You, Ping Chen, S L Rajasekhar Karna, Andrea B Fourcaudot, Eliza A Sebastian, Johnathan J Abercrombie, Uzziel Pineda, Jinson Hong, Nathan A Wienandt, Kai P Leung
We used a modified Walker-Mason scald burn rat model to demonstrate that Pseudomonas aeruginosa, a common opportunistic pathogen in the burn ward and notable biofilm former, establishes biofilms within deep partial-thickness burn wounds in rats.Deep partial-thickness burn wounds, ~10% of the TBSA, were created in anesthetized male Sprague-Dawley rats (350-450 g; n = 84). Immediately post-burn, 100 µl of P. aeruginosa in phosphate-buffered saline at 1 × 103, 1 × 104, or 1 × 105 cells/wound was spread over the burn surface ...
August 20, 2018: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/30107518/multiregional-utilization-of-a-mobile-device-app-for-triage-and-transfer-of-burn-patients
#18
Arek J Wiktor, Laura Madsen, Heather Carmichael, Tyler Smith, Shana Zanyk, Hamed Amani, Anne Lambert Wagner
Technology and telehealth have the potential to optimize burn care in areas limited by lack of expertise and geographic distance from a Burn Center. This study reports a multicenter, multiregional experience using a mobile phone app to facilitate triage of patients by allowing referring providers to send encrypted photos, thus enhancing the telephone consultation process. A retrospective review was conducted on referrals from August 2016 to July 2017 at three regional Burn Centers that utilize the same mobile phone app...
October 23, 2018: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/30010999/the-long-term-impact-of-severe-burn-trauma-on-musculoskeletal-health
#19
Efstathia Polychronopoulou, David N Herndon, Craig Porter
Severe burn injury causes a profound stress response that leads to muscle and bone cachexia. Evidence suggests that these deficits persist for several months or even years after injury and are associated with growth delay, increased incidence of fractures, and increased hospital admissions for musculoskeletal disorders. Thus, there is an overwhelming need to determine the optimal acute and rehabilitative strategies to mitigate these deficits and improve quality of life for burn survivors. To date, there is limited research on the long-term impact of cachexia on functional performance and overall health, as well as on the lasting impact of pharmacological, nutritional, and exercise interventions...
October 23, 2018: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/29931223/renal-replacement-therapy-in-severe-burns-a-multicenter-observational-study
#20
Kevin K Chung, Elsa C Coates, William L Hickerson, Angela L Arnold-Ross, Daniel M Caruso, Marlene Albrecht, Brett D Arnoldo, Christina Howard, Laura S Johnson, Melissa M McLawhorn, Bruce Friedman, Amy M Sprague, Michael J Mosier, David J Smith, Rachel A Karlnoski, James K Aden, Elizabeth A Mann-Salinas, Steven E Wolf
Acute kidney injury (AKI) after severe burns is historically associated with a high mortality. Over the past two decades, various modes of renal replacement therapy (RRT) have been used in this population. The purpose of this multicenter study was to evaluate demographic, treatment, and outcomes data among severe burn patients treated with RRT collectively at various burn centers around the United States. After institutional review board approval, a multicenter observational study was conducted. All adult patients aged 18 or older, admitted with severe burns who were placed on RRT for acute indications but not randomized into a concurrently enrolling interventional trial, were included...
October 23, 2018: Journal of Burn Care & Research: Official Publication of the American Burn Association
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