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Current Rheumatology Reviews

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https://www.readbyqxmd.com/read/29984668/high-levels-of-serum-uric-acid-cystain-c-and-lipids-concentration-and-their-clinical-significance-in-primary-gouty-arthritis-patients
#1
Quan-Bo Zhang, Dan Zhu, Zhong Wen, Ting Yi, Qing Li, Yu-Feng Qing, Jing-Guo Zhou
OBJECTIVE: To investigate the changes of serum uric acid (sUA), lipids and cystatin C (CysC) in primary gout patients, and to explore the clinical significance in gout patients. METHODS: sUA, CysC, high-sensitivity C-reactive protein (hsCRP) and other biochemical parameters were measured in 326 gout patient and 210 healthy control subjects, blood cell counts were also detected. Clinical data were collected from gout patients. RESULTS: sUA, CysC, hsCRP, Body Mass Index (BMI), white blood cell (WBC) counts, neutrophil granulocyte (GR), monocyte (Mo), triglycerides (TG), plasma total cholesterol (TC), very low density lipoprotein (VLDL), apolipoprotein B100 (apoB100), blood glucose (GLU), serum creatinine (sCr) and urea nitrogen (BUN) were significantly increased in gout patients compared with HC subjects (P<0...
July 4, 2018: Current Rheumatology Reviews
https://www.readbyqxmd.com/read/29956634/association-of-serum-homocysteine-level-and-lung-involvement-in-systemic-sclerosis
#2
Asghar Zare, Mohammadali Nazarinia, Mesbah Shams, Mohammad Javad Fallahi
BACKGROUND: Systemic sclerosis (SSc) is a disorder of connective tissue affecting the skin and internal organs, characterized by fibrotic changes of peripheral and visceral architecture. OBJECTIVE: We investigated the correlation between serum concentration of homocysteine and interstitial lung involvement in SSc patients. METHOD: Fifty nine patients with SSc (53 females and 6 males) with a mean age of 43.34 years (range: 17-76 years) were enrolled...
June 28, 2018: Current Rheumatology Reviews
https://www.readbyqxmd.com/read/29952262/self-reported-instability-in-knee-osteoarthritis-a-scoping-review-of-literature
#3
Y V Raghava Neelapala
Knee Osteoarthritis (OA) is a disabling musculoskeletal condition among the elderly. Self-reported instability is one of the impairments associated with osteoarthritis. A complete understanding of the self-reported instability in knee OA is essential, to identify the best strategies for overcoming this impairment. The focus of this scoping review is to provide an overview of evidence supported information about the prevalence and other associated features of self-reported instability in Knee OA. A broad search of the database PubMed with keywords such as knee osteoarthritis and instability resulted in 1075 articles...
June 27, 2018: Current Rheumatology Reviews
https://www.readbyqxmd.com/read/29779484/genetics-and-epigenetics-pathogenesis-of-beh%C3%A3-et-s-syndrome
#4
Jibran Sualeh Muhammad, Muhammad Ishaq, Khalid Ahmed
Behçet's syndrome (BS) is characterized numerous systemic manifestations, is known for its ability to affect both, arteries and the veins. However, the etiology of BS is only partially understood, and previous studies have demonstrated a role of genetic and epigenetic factors contributes to disease pathophysiology. Several studies have implicated the T cells and monocytes, especially when stimulated by seat shock proteins and streptococcal antigen. Furthermore, during disease exacerbations adenosine deaminase has an important role in lymphocyte proliferation, maturation, and differentiation, is activated in Behçet's syndrome...
May 20, 2018: Current Rheumatology Reviews
https://www.readbyqxmd.com/read/29766817/characteristics-and-outcomes-of-patients-with-anti-glomerular-basement-membrane-antibody-disease-and-anti-neutrophil-cytoplasmic-antibodies
#5
Percy G Balderia, Nicole Andeen, Jonathan A Jefferson
BACKGROUND: It is unclear whether patients with anti-glomerular basement membrane (GBM) disease and anti-neutrophil cytoplasmic antibodies (ANCA), so called "double-positive" (DP), have a different clinical presentation and outcome compared to patients with anti-GBM antibody disease alone. This study describes the clinical and histologic characteristics as well as the patient and renal outcomes of DP patients at the University of Washington compared to patients with anti-GBM antibody disease alone...
May 16, 2018: Current Rheumatology Reviews
https://www.readbyqxmd.com/read/29756580/subtypes-of-antiphospholipid-antibodies-in-neurologic-accidents-an-observational-study
#6
Maryam Sahebari, Maryam Rastin, Reza Boostani, Mohsen Forughipour, Kamila Hashemzadeh, Samira HaajSadeghi
OBJECTIVE: Until now, concomitant neurological manifestations and positive antiphospholipid antibodies (APA(s)) have been investigated in different manners. The most important conflicts in this field are whether those manifestations are directly related to APA(s) or not and treatment strategies. METHOD: In this study, adopting a different manner, we selected patients with a recently defined neurological problem (according to study protocol) and positive APA without any other risk factor, to compare types, amounts, and titer of APAs...
May 14, 2018: Current Rheumatology Reviews
https://www.readbyqxmd.com/read/29708075/risk-factors-associated-with-musculoskeletal-injury-a-prospective-study-of-british-infantry-recruits
#7
Jagannath Sharma, R Heagerty, S Dalal, B Banerjee, T Booker
BACKGROUND: Musculoskeletal injury (MSKI), a common problem in both military and physically active civilian populations has been suggested to result from both extrinsic and intrinsic factors. OBJECTIVE: This study was to investigate prospectively whether gait biomechanics, aerobic fitness level and smoking status as well as entry military selection test variables can be used to predict MSKI development during recruit training. METHOD: British infantry male recruits (n = 562) were selected for the study...
April 29, 2018: Current Rheumatology Reviews
https://www.readbyqxmd.com/read/29692254/musculoskeletal-manifestations-of-sarcoidosis-a-review-article
#8
Somayeh Shariatmaghani, Roshanak Salari, Maryam Sahebari, Payman Shalchiantabrizi, Masoumeh Salari
Sarcoidosis is a multisystem inflammatory disease with an etiology that is not clearly understood. Amongst the different organs that may be affected, the lungs are the most common. Musculoskeletal manifestations of the disease are uncommon. They include arthropathy, bone lesions, or myopathy, all of which may occur as initial symptoms or develop during the course of the disease. Articular involvement my present as arthralgia or arthritis. Skeletal complications usually develop in the chronic state of the disease...
April 24, 2018: Current Rheumatology Reviews
https://www.readbyqxmd.com/read/29692256/gauzoma-in-a-scleroderma-patient-following-open-heart-surgery-a-case-report
#9
Mohammadali Nazarinia, Elmira Esmaeilzadeh
INTRODUCTION: Gauzoma is an iatrogenic complication, which occurs rarely due to surgical team negligence. Depending on the sterility of the retained tissue, it can lead to life threatening surgical complications or may remain asymptomatic for many years and be detected incidentally in imaging studies. It may be mistaken as tumors or aneurysms. Thus, high clinical suspicion is needed to diagnose them in patients with past history of operation. Reporting Case: A 35 years old woman, a known case of scleroderma underwent open-heart surgery 20 years before being diagnosed as scleroderma, presented by dyspnea especially on activity...
April 22, 2018: Current Rheumatology Reviews
https://www.readbyqxmd.com/read/29692255/juvenile-scleroderma-what-has-changed-in-the-meantime
#10
Amra Adrovic, Sezgin Sahin, Kenan Barut, Ozgur Kasapcopur
BACKGROUND: Juvenile scleroderma is a rarely seen chronic connective tissue disorder characterized by stiffening of the skin. The frequency of the disease was reported as one per million. According to organ involvement, the disease is divided into two main forms: systemic and localized scleroderma. OBJECTIVES: Since it is uncommon in children, many aspects of the disease remain discussable. With this review, we aimed to revise recent findings and new developments in this rare condition...
April 22, 2018: Current Rheumatology Reviews
https://www.readbyqxmd.com/read/29446745/editorial-nailfold-capillaroscopy-in-rheumatology
#11
EDITORIAL
Sevdalina Nikolova Lambova, Ulf Muller-Ladner
No abstract text is available yet for this article.
April 20, 2018: Current Rheumatology Reviews
https://www.readbyqxmd.com/read/29057725/prevalence-of-nasal-colonization-with-staphylococcus-aureus-in-patients-with-rheumatoid-arthritis
#12
Gloria Albert, Milagros Ricse, Javier Narvaez, Jesus Rodriguez-Moreno, Joan M Nolla, MAngeles Dominguez-Luzon, Carmen Gomez-Vaquero
Objetive: Patients with Rheumatoid Arthritis (RA) and nasal carriers of Staphylococcus aureus have an increased risk of developing infections caused by S. aureus. Our objective was to determine the prevalence of S. aureus nasal colonization in patients with RA and its relationship to RA treatments. METHODS: Two hundred and seven patients with RA and 37 healthy controls were prospectively included in a cross-sectional study. A nasal secretion sample was collected by swab from both anterior nostrils and was referred to the hospital's microbiology department for culturing...
April 20, 2018: Current Rheumatology Reviews
https://www.readbyqxmd.com/read/29046162/potential-role-of-rebamipide-in-osteoclast-differentiation-and-mandibular-condylar-cartilage-homeostasis
#13
Takashi Izawa, Islamy Rahma Hutami, Eiji Tanaka
BACKGROUND: Temporomandibular joint osteoarthritis (TMJ-OA) is a degenerative disease that involves changes in subchondral bone and progressive degradation of cartilage. Currently, rebamipide, a gastroprotective drug, is administered to protect gastric mucosa and accelerate ulcer healing. OBJECTIVES: Recent studies have shown that rebamipide also attenuates cartilage degeneration by suppressing oxidative damage and inducing homeostasis of the extracellular matrix of articular chondrocytes...
April 20, 2018: Current Rheumatology Reviews
https://www.readbyqxmd.com/read/28828986/lipid-profile-of-children-suffering-from-pediatric-rheumatic-diseases-prds
#14
A K M Mamunur Rashid, Habiba Sultana, Tasnuva Islam, Palash Bishwas
BACKGROUND: Aim of this study was to assess the lipid status of the patients of pediatric rheumatologic diseases (pRDS). METHODS: This observational study was carried out in the department of pediatrics, Khulna medical college hospital, Bangladesh for a period of one year. Total 23 patients were included in this study. These new cases were diagnosed according to the ILAR, ACR, and EULAR criteria. Early morning blood samples were sent to the laboratory for the assessment of lipid status (TC, TG, HDL, and LDL)...
April 20, 2018: Current Rheumatology Reviews
https://www.readbyqxmd.com/read/28745214/nailfold-capillaroscopy-of-fingers-and-toes-variations-of-normal
#15
Sevdalina Nikolova Lambova, Ulf Muller-Ladner
BACKGROUND: Nailfold capillaroscopy is the only method for morphological assessment of nutritive capillaries. The literature data about capillaroscopic findings in healthy individuals are scarce. OBJECTIVE: To evaluate and compare the capillaroscopic findings of fingers and toes in healthy subjects. MATERIALS AND METHODS: 22 healthy individuals were included in the study. Capillaroscopic examination was performed with videocapillaroscope Videocap 3...
April 20, 2018: Current Rheumatology Reviews
https://www.readbyqxmd.com/read/28641553/capillaroscopy-in-routine-diagnostics-potentials-and-limitations
#16
Francesca Ingegnoli, Vanessa Smith, Alberto Sulli, Maurizio Cutolo
BACKGROUND: Nailfold capillaroscopy is a safe and useful investigational tool that allows an early detection and a qualitative description of the microvascular abnormalities in patients with Raynaud's phenomenon secondary to scleroderma-spectrum disorders. Nowadays, the role of capillaroscopy in the diagnosis of systemic sclerosis is well known. Capillaroscopy has been included in the new 2013 classification criteria for systemic sclerosis and is considered a key investigation in the very early phases of the disease...
April 20, 2018: Current Rheumatology Reviews
https://www.readbyqxmd.com/read/28641551/nailfold-capillaroscopy-within-and-beyond-the-scope-of-connective-tissue-diseases
#17
Sevdalina Nikolova Lambova, Ulf Muller-Ladner
Nailfold capillaroscopy is a noninvasive instrumental method for morphological analysis of the nutritive capillaries in the nailfold area. In rheumatology, it is a method of choice among instrumental modalities for differential diagnosis between primary and secondary Raynaud's phenomenon (RP) in systemic rheumatic diseases. RP is a common diagnostic problem in rheumatology. Defining the proper diagnosis is a prerequisite for administration of the appropriate treatment. Thus, nailfold capillaroscopic examination is of crucial importance for the every-day practice of the rheumatologists and is currently gaining increasing attention...
April 20, 2018: Current Rheumatology Reviews
https://www.readbyqxmd.com/read/28641550/bier-spots-report-of-two-cases-and-review-of-the-literature
#18
Hristo Dobrev, Desislava Nocheva
BACKGROUND: Bier spots are asymptomatic white anemic macules with irregular shape located on the upper limbs and less often on the lower limbs and trunkus. They are observed predominantly in youg males and may be idiopathic or associated with other conditions. OBJECTIVE: We report two cases with Bier spots in which videodermatoscopy and nailfold capillaroscopy were performed. RESULTS: Patient 1 was a 34-year-old otherwise healthy male who presented with white spots on his upper limbs for 10 years...
April 20, 2018: Current Rheumatology Reviews
https://www.readbyqxmd.com/read/28606036/scleroderma-like-disorders
#19
Amit Sharma
BACKGROUND: Scleroderma is a term used to describe diseases that involve hardening and tightening of the skin and the underlying subcutaneous connective tissue. It could be localized to skin and subcutaneous tissue, or may involve the internal organs too in systemic sclerosis. OBJECTIVE: There are disorders that can cause hardening and tightening of skin and mimic scleroderma but are rarely associated with Raynaud phenomenon, sclerodactyly, and autoantibodies in the serum, features specific to scleroderma/systemic sclerosis...
April 20, 2018: Current Rheumatology Reviews
https://www.readbyqxmd.com/read/28595537/capillaroscopic-findings-in-primary-fibromyalgia
#20
Sevdalina Nikolova Lambova, Ulf Muller-Ladner
INTRODUCTION: Although Raynaud's Phenomenon (RP) is observed in a significant proportion of patients with primary fibromyalgia, the available data on capillaroscopic findings in primary fibromyalgia are scarce. OBJECTIVE: The purpose of the study was to assess the capillaroscopic pattern in patients with primary fibromyalgia. PATIENTS AND METHODS: 26 patients with primary fibromyalgia (25 women and 1 man) were included in the study. Mean age was 55±10 years...
April 20, 2018: Current Rheumatology Reviews
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