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Journal of Oncology Practice

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https://www.readbyqxmd.com/read/29155612/health-reform-and-utilization-of-high-volume-hospitals-for-complex-cancer-operations
#1
Andrew P Loehrer, David C Chang, Zirui Song, George J Chang
PURPOSE: Underinsured patients are less likely to receive complex cancer operations at hospitals with high surgical volumes (high-volume hospitals, or HVHs), which contributes to disparities in care. To date, the impact of insurance coverage expansion on site of complex cancer surgery remains unknown. METHODS: Using the 2006 Massachusetts coverage expansion as a natural experiment, we searched the Hospital Cost and Utilization Project state inpatient databases for Massachusetts and control states (New York, New Jersey, and Florida) between 2001 and 2011 to evaluate changes in the utilization of HVHs for resections of bladder, esophageal, stomach, pancreatic, rectal, or lung cancer after the expansion of insurance coverage...
November 20, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/29155611/can-chemotherapy-related-acute-care-visits-be-accurately-identified-in-administrative-data
#2
Monika K Krzyzanowska, Katherine Enright, Rahim Moineddin, Lingsong Yun, Melanie Powis, Mohammed Ghannam, Eva Grunfeld
PURPOSE: There is increasing interest in using administrative data to examine treatment-related complications that lead to emergency department (ED) visits or hospitalizations (H). The purpose of this study was to evaluate the reliability of billing codes for identifying chemotherapy-related acute care visits (CRVs) among women with early-stage breast cancer. MATERIALS AND METHODS: The cohort was identified by using deterministically linked health databases and consisted of women who were diagnosed with early-stage breast cancer who started adjuvant chemotherapy between 2007 and 2009 in Ontario, Canada...
November 20, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/29144866/challenges-in-the-clinical-application-of-the-american-society-of-clinical-oncology-value-framework-a-medicare-cost-benefit-analysis-in-chronic-lymphocytic-leukemia
#3
Erlene K Seymour, Charles A Schiffer, Jonas A de Souza
PURPOSE: The ASCO Value Framework calculates the value of cancer therapies. Given costly novel therapeutics for chronic lymphocytic leukemia, we used the framework to compare net health benefit (NHB) and cost within Medicare of all regimens listed in the National Comprehensive Cancer Network (NCCN) guidelines. METHODS: The current NCCN guidelines for chronic lymphocytic leukemia were reviewed. All referenced studies were screened, and only randomized controlled prospective trials were included...
November 16, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/29144865/macra-in-oncology-care-are-we-ready
#4
Chadi Nabhan, Alima Tchafa, Bruce A Feinberg
No abstract text is available yet for this article.
November 16, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/29144864/reply-to-m-mckenzie-et-al
#5
Harry Peled, Kathleen Bickel, Christina Puchalski
No abstract text is available yet for this article.
November 16, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/29144863/in-response-to-medical-assistance-in-dying-in-canada
#6
Michael Ross McKenzie, Philippa Hawley, Doris Barwich, Howard J Lim
No abstract text is available yet for this article.
November 16, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/29144862/are-physician-orders-for-life-sustaining-treatments-the-answer-to-the-end-of-life-care-quality-conundrums-in-cancer-care
#7
Keith M Swetz
No abstract text is available yet for this article.
November 16, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/29136390/assurance-of-myeloid-growth-factor-administration-in-an-infusion-center-pilot-quality-improvement-initiative
#8
Pamela Maree Ramirez, Barry Peterson, Christine Holtshopple, Kristina Borja, Vincent Torres, Lucille Valdivia-Peppers, Julio Harriague, Melanie D Joe
PURPOSE: Four incident reports involving missed doses of myeloid growth factors (MGFs) triggered the need for an outcome-driven initiative. From March 1, 2015, to February 29, 2016, at University of California Irvine Health Chao Infusion Center, 116 of 3,300 MGF doses were missed (3.52%), including pegfilgrastim, filgrastim, and sargramostim. We hypothesized that with the application of Lean Six Sigma methodology, we would achieve our primary objective of reducing the number of missed MGF doses to < 0...
November 14, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/29136389/factors-that-influence-fda-decisions-for-postmarketing-requirements-and-commitments-during-review-of-oncology-products
#9
Atsushi Hyogo, Masayuki Kaneko, Mamoru Narukawa
PURPOSE: With the recent use of expedited drug development and approval programs for several oncology products in the United States, the importance of postmarketing plans to confirm clinical benefits and safety is increasing. To discuss postmarketing requirements (PMRs) and postmarketing commitments (PMCs) required for oncology products approved in the United States, we investigated the factors that influenced the US Food and Drug Administration (FDA) decisions for PMR/PMCs during FDA review...
November 14, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/29099678/representation-of-minorities-and-women-in-oncology-clinical-trials-review-of-the-past-14-years
#10
Narjust Duma, Jesus Vera Aguilera, Jonas Paludo, Candace L Haddox, Miguel Gonzalez Velez, Yucai Wang, Konstantinos Leventakos, Joleen M Hubbard, Aaron S Mansfield, Ronald S Go, Alex A Adjei
PURPOSE: Many cancer clinical trials lack appropriate representation of specific patient populations, limiting their generalizability. Therefore, we determined the representation of ethnic minorities and women in cancer clinical trials. METHODS: Enrollment data from all therapeutic trials reported as completed in ClinicalTrials.gov from 2003 to 2016 were analyzed. We calculated enrollment fractions (EFs) for each group, defined as the number of enrollees divided by the 2013 Surveillance, Epidemiology, and End Results (SEER) database cancer prevalence...
November 3, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/29091535/survival-as-a-quality-metric-of-cancer-care-use-of-the-national-cancer-data-base-to-assess-hospital-performance
#11
Lawrence N Shulman, Bryan E Palis, Ryan McCabe, Kathy Mallin, Ashley Loomis, David Winchester, Daniel McKellar
PURPOSE: Survival is considered an important indicator of the quality of cancer care, but the validity of different methodologies to measure comparative survival rates is less well understood. We explored whether the National Cancer Data Base (NCDB) could serve as a source of unadjusted and risk-adjusted cancer survival data and whether these data could be used as quality indicators for individual hospitals or in the aggregate by hospital type. METHODS: The NCDB, an aggregate of > 1,500 hospital cancer registries, was queried to analyze unadjusted and risk-adjusted hazards of death for patients with stage III breast cancer (n = 116,787) and stage IIIB or IV non-small-cell lung cancer (n = 252,392)...
November 1, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/29091534/american-society-of-clinical-oncology-position-statement-on-addressing-the-affordability-of-cancer-drugs
#12
(no author information available yet)
No abstract text is available yet for this article.
November 1, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/29068751/radiation-therapy-for-oropharyngeal-squamous-cell-carcinoma-american-society-of-clinical-oncology-endorsement-of-the-american-society-for-radiation-oncology-evidence-based-clinical-practice-guideline-summary
#13
Harry Quon, Neha Vapiwala, Arlene Forastiere, Erin B Kennedy
No abstract text is available yet for this article.
October 25, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/29048991/impacts-of-early-guideline-directed-21-gene-recurrence-score-testing-on-adjuvant-therapy-decision-making
#14
Hannah Dzimitrowicz, Sarah Mougalian, Sherri Storms, Sandra Hurd, Anees B Chagpar, Brigid K Killelea, Nina R Horowitz, Donald R Lannin, Malini Harigopal, Erin Hofstatter, Michael P DiGiovanna, Kerin B Adelson, Andrea Silber, Maysa Abu-Khalaf, Gina Chung, Wajih Zaheer, Osama Abdelghany, Christos Hatzis, Lajos Pusztai, Tara B Sanft
PURPOSE: The 21-gene recurrence score (RS) assay is used to help formulate adjuvant chemotherapy recommendations for patients with estrogen receptor-positive, early-stage breast cancer. Most frequently, medical oncologists order RS after surgery. Results take an additional 2 weeks to return, which can delay decision making. We conducted a prospective quality-improvement project to assess the impact of early guideline-directed RS ordering by surgeons before the first visit with a medical oncologist on adjuvant therapy decision making...
October 19, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/29035618/impact-of-intensity-modulated-radiotherapy-on-health-care-costs-of-patients-with-anal-squamous-cell-carcinoma
#15
Alexander L Chin, Erqi L Pollom, Yushen Qian, Albert C Koong, Daniel T Chang
PURPOSE: Drivers of variation in the cost of care after chemoradiotherapy for the management of anal squamous cell carcinoma (SCC) have not been fully elucidated. We sought to characterize the direct and indirect impact of radiotherapy modality on health care costs among patients with anal SCC. PATIENTS AND METHODS: A retrospective cohort study was performed using the 2014 linkage of the SEER-Medicare database. We identified 1,025 patients with anal SCC diagnosed between 2001 and 2011 and treated with chemoradiotherapy...
October 16, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/29035617/role-of-bone-modifying-agents-in-metastatic-breast-cancer-an-american-society-of-clinical-oncology-cancer-care-ontario-focused-guideline-update-summary
#16
Catherine Van Poznak, Mark R Somerfield, Beverly Moy
No abstract text is available yet for this article.
October 16, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/29028418/cancer-center-clinic-and-research-team-perceptions-of-identity-and-interactions
#17
Torsten Reimer, Simon J Craddock Lee, Sandra Garcia, Mary Gill, Tobi Duncan, Erin L Williams, David E Gerber
PURPOSE: Conduct of cancer clinical trials requires coordination and cooperation among research and clinic teams. Diffusion of and confusion about responsibility may occur if team members' perceptions of roles and objectives do not align. These factors are critical to the success of cancer centers but are poorly studied. METHODS: We developed a survey adapting components of the Adapted Team Climate Inventory, Measure of Team Identification, and Measure of In-Group Bias...
October 13, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/29028417/opioid-prescription-trends-among-patients-with-cancer-referred-to-outpatient-palliative-care-over-a-6-year-period
#18
Ali Haider, Donna S Zhukovsky, Yee Choon Meng, Joseph Baidoo, Kimberson C Tanco, Holly A Stewart, Tonya Edwards, Manju P Joy, Leela Kuriakose, Zhanni Lu, Janet L Williams, Diane D Liu, Eduardo Bruera
INTRODUCTION: In the United States, opioid regulations have become increasingly stringent in recent years. Increased regulatory scrutiny, in part, is related to heightened awareness through literature and a recent media blitz on the opioid prescription epidemic. These regulations have the potential to impact prescription trends by health care providers. Our objective was to evaluate changes in the type and dose of opioid prescriptions among patients who are referred by oncologists to an outpatient palliative care clinic...
October 13, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/29019706/institutional-scientific-review-of-cancer-clinical-research-protocols-a-unique-requirement-that-affects-activation-timelines
#19
Ning Ning, Jingsheng Yan, Martin F Dietrich, Xian-Jin Xie, David E Gerber
PURPOSE: The National Cancer Institute (NCI) requirement that clinical trials at NCI-designated cancer centers undergo institutional scientific review in addition to institutional review board evaluation is unique among medical specialties. We sought to evaluate the effect of this process on protocol activation timelines. METHODS: We analyzed oncology clinical trials that underwent full board review by the Harold C. Simmons Comprehensive Cancer Center Protocol Review and Monitoring Committee (PRMC) from January 1, 2009, through June 30, 2013...
October 11, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/29016225/asco-value-framework-highlights-the-relative-value-of-treatment-options-in-ovarian-cancer
#20
Jonathan Foote, Angeles Alvarez Secord, Margaret Liang, David E Cohn, Elizabeth Jewell, Laura J Havrilesky
PURPOSE: The ASCO value framework allows physicians and patients to compare the relative value of novel treatments. Our aim was to assess the value of three frontline ovarian cancer therapies by using this framework. METHODS: From phase III, randomized controlled clinical trial (RCT) data, the net health benefits (NHBs) for three frontline ovarian cancer treatment options-dose-dense paclitaxel (Japanese Gynecologic Oncology Group study JGOG 3016), intraperitoneal (IP)/intravenous (IV) chemotherapy (Gynecologic Oncology Group [GOG] study GOG 172), and concurrent plus maintenance bevacizumab (GOG 218 and the Seventh International Collaborative Ovarian Neoplasm study [ICON7])-were calculated...
October 10, 2017: Journal of Oncology Practice
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