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Journal of Oncology Practice

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https://www.readbyqxmd.com/read/28644706/advance-care-planning-and-palliative-care-integration-for-patients-undergoing-hematopoietic-stem-cell-transplantation
#1
Winnie S Wang, Joseph D Ma, Sandahl H Nelson, Carolyn Revta, Gary T Buckholz, Carolyn M Mulroney, Eric J Roeland
PURPOSE: Advance care planning (ACP) in hematopoietic stem-cell transplantation (HSCT) is challenging, given the potential for cure despite increased morbidity and mortality risk.The aim of this study was to evaluate ACP and palliative care (PC) integration for patients who underwent HSCT. METHODS: A retrospective analysis was conducted and data were extracted from electronic medical records of patients who underwent HSCT between January 2011 and December 2015. Patients who received more than one transplant and who were younger than 18 years of age were excluded...
June 23, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/28636421/analysis-of-origins-of-admission-for-solid-tumor-oncology-inpatients-disease-severity-and-outcomes
#2
Christopher E Wee, Lindsey M Goodman, Leticia Varella, Lisa A Rybicki, Alberto J Montero, Bassam N Estfan, Carolyn H Best, James P Stevenson
PURPOSE: Hospital transfers may affect clinical outcomes. Evaluation of admission by source of transfer, time of admission, and provider type may identify opportunities to improve inpatient outcomes. METHODS: We reviewed charts of patients admitted to the solid tumor oncology service between July and December 2014 from the Cleveland Clinic Foundation (CCF) Main Campus emergency department (ED), CCF Regional EDs, outside hospital (OSH) ED, OSH inpatient services, and CCF outpatient clinics...
June 21, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/28628393/early-national-dissemination-of-abiraterone-and-enzalutamide-for-advanced-prostate-cancer-in-medicare-part-d
#3
Megan E V Caram, Tudor Borza, Hye-Sung Min, Jennifer J Griggs, David C Miller, Brent K Hollenbeck, Bhramar Mukherjee, Ted A Skolarus
INTRODUCTION: Abiraterone and enzalutamide were approved by the Food and Drug Administration in 2011 and 2012 to treat men with metastatic castration-resistant prostate cancer (mCRPC). Most men with mCRPC are > 65 years of age and thus eligible for Medicare Part D. We conducted a study to better understand the early dissemination of these drugs across the United States using national Medicare Part D data. METHODS: We evaluated the number of prescriptions for abiraterone and enzalutamide by provider specialty and hospital referral region (HRR) using Medicare Part D and Dartmouth Atlas data...
June 19, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/28628392/potential-drug-drug-and-herb-drug-interactions-in-patients-with-cancer-a-prospective-study-of-medication-surveillance
#4
Allan Ramos-Esquivel, Álvaro Víquez-Jaikel, Cristina Fernández
PURPOSE: Patients with cancer frequently use herbal supplements and concomitant medications along with antineoplastic agents. These patients are at high risk of herb-drug interactions (HDIs) and drug-drug interactions (DDIs). We aimed to determine clinically relevant DDIs and HDIs leading to pharmaceutical intervention. METHODS: Patients starting a new anticancer therapy were asked to complete a questionnaire to identify concomitant use of any over-the-counter drug or herbal supplement...
June 19, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/28628391/interest-and-attitudes-of-patients-with-advanced-cancer-with-regard-to-secondary-germline-findings-from-tumor-genomic-profiling
#5
Jada G Hamilton, Elyse Shuk, Margaux C Genoff, Vivian M Rodríguez, Jennifer L Hay, Kenneth Offit, Mark E Robson
PURPOSE: Tumor genomic profiling (TGP) can reveal secondary findings about inherited disease risks in a patient with cancer. Little is known about how patients with advanced cancer, currently the primary users of TGP, perceive the benefits and harms of secondary germline findings. METHODS: We conducted semistructured interviews with 40 patients with advanced breast, bladder, colorectal, or lung cancer who had TGP. Qualitative interview data were evaluated by using a thematic content analysis approach...
June 19, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/28617618/value-based-calculators-in-cancer-current-state-and-challenges
#6
Chadi Nabhan, Bruce A Feinberg
The ASCO Value Framework, National Comprehensive Cancer Network Evidence Blocks, Memorial Sloan Kettering's DrugAbacus, and Institute for Clinical and Economic Review incremental cost-effectiveness ratio calculator are value-based methodologies that attempt to address the disproportionate increase in cancer care spending. These calculators can be used as an initial step for discussing cost versus value, but they fall short in recognizing the importance of the cancer journey because they do not fully factor the patient's perspective or the global cost of care...
June 15, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/28613970/is-this-conference-for-real-navigating-presumed-predatory-conference-invitations
#7
Kelly D Cobey, Miguel de Costa E Silva, Sasha Mazzarello, Carol Stober, Brian Hutton, David Moher, Mark Clemons
No abstract text is available yet for this article.
June 14, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/28613969/creation-of-institute-of-medicine-care-plans-with-an-eye-on-up-front-care
#8
Gabrielle B Rocque, Austin Cadden
No abstract text is available yet for this article.
June 14, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/28613968/clinician-engagement-and-guideline-development-enhancing-an-evidence-based-culture-for-quality-cancer-care-the-2017-joseph-v-simone-award-and-lecture
#9
George P Browman
No abstract text is available yet for this article.
June 14, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/28605255/financial-impact-of-cancer-drug-wastage-and-potential-cost-savings-from-mitigation-strategies
#10
Caitlyn Y W Leung, Matthew C Cheung, Lauren F Charbonneau, Anca Prica, Pamela Ng, Kelvin K W Chan
PURPOSE: Cancer drug wastage occurs when a parenteral drug within a fixed vial is not administered fully to a patient. This study investigated the extent of drug wastage, the financial impact on the hospital budget, and the cost savings associated with current mitigation strategies. METHODS: We conducted a cross-sectional study in three University of Toronto-affiliated hospitals of various sizes. We recorded the actual amount of drug wasted over a 2-week period while using current mitigation strategies...
June 12, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/28605254/impact-of-immigration-status-on-cancer-outcomes-in-ontario-canada
#11
Matthew C Cheung, Craig C Earle, Hadas D Fischer, Ximena Camacho, Ning Liu, Refik Saskin, Baiju R Shah, Peter C Austin, Simron Singh
BACKGROUND: Prior studies have documented inferior health outcomes in vulnerable populations, including racial minorities and those with disadvantaged socioeconomic status. The impact of immigration on cancer-related outcomes is less clear. METHODS: Administrative databases were linked to create a cohort of incident cancer cases (colorectal, lung, prostate, head and neck, breast, and hematologic malignancies) from 2000 to 2012 in Ontario, Canada. Cancer patients who immigrated to Canada (from 1985 onward) were compared with those who were Canadian born (or immigrated before 1985)...
June 12, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/28594585/impact-of-palliative-medicine-involvement-on-end-of-life-services-for-patients-with-cancer-with-in-hospital-deaths
#12
Alison Wiesenthal, Debra A Goldman, Deborah Korenstein
PURPOSE: Palliative care (PC) has been shown to improve the quality of care and resource utilization for inpatients. We examined the relationship between PC consultation before and during final admission and patterns of care for dying patients at our tertiary cancer center. METHODS: We retrospectively reviewed adult patients with solid tumor cancer with a length of stay ≥ 3 days who died in hospital between December 2012 and November 2014. We recorded services, including laboratory testing, imaging, blood products, medications, diet orders, do not resuscitate orders, and consultations, delivered within 3 days of death...
June 8, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/28590794/transforming-practices-through-the-oncology-care-model-financial-toxicity-and-counseling
#13
Daniel E Sherman
No abstract text is available yet for this article.
June 7, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/28586259/implementation-of-advance-care-planning-in-oncology-a-review-of-the-literature
#14
Christine M Bestvina, Blase N Polite
Advance care planning (ACP) should be initiated early and be readdressed often for patients with cancer. This directive is expressed in the Institute of Medicine's report, "Dying in America," and is a component of several quality metrics, including ASCO's Quality Oncology Practice Initiative and the Centers for Medicare & Medicaid Services Oncology Care Model. Although simple in concept, implementation in practice is challenging. A variety of patient education tools exist in several different forms, including pamphlets, guidebooks, and question prompt lists, with the strongest data supporting the use of video decision aids that depict cardiopulmonary resuscitation...
June 6, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/28562197/improving-end-of-life-care-palliative-care-embedded-in-an-oncology-clinic-specializing-in-targeted-and-immune-based-therapies
#15
David J Einstein, Susan DeSanto-Madeya, Matthew Gregas, Jessica Lynch, David F McDermott, Mary K Buss
PURPOSE: Patients with advanced cancer benefit from early involvement of palliative care. The ideal method of palliative care integration remains to be determined, as does its effectiveness for patients treated with targeted and immune-based therapies. MATERIALS AND METHODS: We studied the impact of an embedded palliative care team that saw patients in an academic oncology clinic specializing in targeted and immune-based therapies. Patients seen on a specific day accessed the embedded model, on the basis of automatic criteria; patients seen other days could be referred to a separate palliative care clinic (usual care)...
May 31, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/28562196/antitumor-and-anti-hepatitis-c-viral-response-after-administration-of-the-anti-programmed-death-1-antibody-pembrolizumab
#16
Sekwon Jang, Suraj Venna
No abstract text is available yet for this article.
May 31, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/28557661/opioids-in-cancer-pain-right-or-privilege
#17
Leanne K Jackson, Syed N Imam, Ursula K Braun
Opioid analgesia is a mainstay of the treatment of cancer pain. Treatment of pain in patients with cancer with an ongoing substance abuse disorder can be difficult. We report the ethical challenges of treating a patient with cancer with a concomitant substance abuse disorder in an outpatient palliative care setting. We present an analysis of ethical considerations for the palliative care physician and strategies to aid in the successful treatment of such patients. We argue that there are select patients with cancer for whom exclusion from treatment with opioid therapy is warranted if their health is endangered by prescription of these medications...
May 30, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/28557660/diagnosing-primary-squamous-cell-cancer-of-the-rectum-in-a-patient-with-hiv-a-case-report
#18
Pushpinderdeep S Kahlon, Ashish Mishra, Todd R Williams, Nimrat K Sandhu, Vijayalaksmi Donthireddy, Irina Dobrostoskaya
No abstract text is available yet for this article.
May 30, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/28541789/primary-prevention-of-cervical-cancer-american-society-of-clinical-oncology-resource-stratified-guideline-summary
#19
Silvia de Sanjosé, Sarah Temin, Suzanne Garland, Linda O'Neal Eckert, Silvina Arrossi
No abstract text is available yet for this article.
May 25, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/28541788/addressing-hereditary-cancer-risk-at-the-end-of-life
#20
Eric J Roeland, Alexandra D Dullea, Chelsea H Hagmann, Lisa Madlensky
Oncology guidelines clearly outline evidence-based recommendations for patients with newly diagnosed cancer to help oncologists determine which patients are appropriate for a genetic assessment. Ideally, patients with newly diagnosed cancer, who have personal or family histories suggestive of hereditary cancer predisposition, are referred for genetics work up in the nonurgent setting. However, in some cases, a genetics work up is delayed until the end of life. This is a time of heightened stress and additional obstacles, including discordance between family members regarding the obtainment of genetic information, paying for testing, selecting a surrogate to receive and disperse information in the case of a patient's death, and the use of DNA banking for future evaluation...
May 25, 2017: Journal of Oncology Practice
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