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Journal of Cardiovascular Medicine

Sergio D'Addato, Silvia Palmisano, Claudio Borghi
No abstract text is available yet for this article.
October 18, 2016: Journal of Cardiovascular Medicine
Francesco Fattirolli, Alessandra Pratesi, Simone Venturini
No abstract text is available yet for this article.
October 18, 2016: Journal of Cardiovascular Medicine
Paolo Giorgini, Paolo Di Giosia, Livia Ferri, Claudio Ferri
No abstract text is available yet for this article.
October 15, 2016: Journal of Cardiovascular Medicine
Enrico Natale, Massimo Pistono
No abstract text is available yet for this article.
October 15, 2016: Journal of Cardiovascular Medicine
Sergio E Masnaghetti, Simona Sarzi Braga, Raffaella Vaninetti, Paola Baiardi, Roberto F E Pedretti
BACKGROUND AND AIMS: Hospitalized patients after acute cardiovascular events have poorer prognosis if glucose regulation is diagnosed as abnormal. We compared the short and long-term outcome of patients with newly diagnosed altered fasting glycemia (AFG) to that of known diabetic patients and patients with normal glucose regulation (NGR) after admission to cardiac rehabilitation. METHODS: We retrospectively analyzed 2490 consecutive patients. Three groups were identified: known diabetes mellitus (n = 540, 22%), fasting glycemia above 110 mg/dl (AFG, n = 269, 11%), and fasting glycemia 110 mg/dl or less (NGR, n = 1681, 67%)...
October 15, 2016: Journal of Cardiovascular Medicine
Alessia Urbinati, Pierpaolo Pellicori, Federico Guerra, Alessandro Capucci, Andrew L Clark
We describe the case of a takotsubo syndrome in a 12-year-old male patient following an acute intracranial haemorrhage, which had a favourable outcome. We also performed a systematic review of published case reports in patients younger than 18 years. Although takotsubo syndrome is common in postmenopausal women, in the paediatric population it equally affects both sexes. Compared with adults, paediatric patients more commonly present with heart failure symptoms or loss of consciousness. A higher proportion of paediatric patients have ST segment depression on ECG...
September 24, 2016: Journal of Cardiovascular Medicine
Valentina Favalli, Alessandra Serio, Lorenzo Paolo Giuliani, Eloisa Arbustini
No abstract text is available yet for this article.
September 22, 2016: Journal of Cardiovascular Medicine
Marco Araco, Marco Merlo, Gerald Carr-White, Gianfranco Sinagra
Cardiomyopathies represent a wide and heterogeneous group of diseases wherein a genetic cause has been consistently identified.Dilated cardiomyopathy (DCM) is characterized by ventricular dilation and progressive systolic dysfunction, and it is the most common form of cardiomyopathy.Causative genetic mutations have been identified in more than 40 genes encoding proteins belonging to different cellular structures and pathways.A great diversity of pathways has been implied in the pathogenesis of DCM, depending on the affected genes and on the dislodged intracellular structures or mechanisms...
September 22, 2016: Journal of Cardiovascular Medicine
Fabio Marsico, Stefania Paolillo, Pasquale Perrone Filardi
NSAIDs are the most largely used class of drugs in the world, due to their large use in many diseases, in particular for the systemic inflammatory diseases. Nevertheless, today NSAIDs are less used for some of these diseases, due to several side-effects correlated to these drugs. The antiinflammatory mechanism of NSAIDs consist in the inibhition of two forms of cyclooxygenase, namely COX-1 (its block contributes to an antiplatelet effect) and COX-2 (its block has a greater antiinflammatory, antipyretic and analgesic effect)...
September 20, 2016: Journal of Cardiovascular Medicine
Paolo Verdecchia, Fabio Angeli, Gianpaolo Reboldi
No abstract text is available yet for this article.
September 20, 2016: Journal of Cardiovascular Medicine
Francesco Giannini, Antonio Colombo
No abstract text is available yet for this article.
September 20, 2016: Journal of Cardiovascular Medicine
Luca Conte, Andrea Rossi, Claudio Picariello, Marco Zuin, Riccardo G Abbasciano, Gianluca Rigatelli, Loris Roncon
In spite of the evolution of diagnostic and imaging tools, infective endocarditis still remains a challenging diagnostic problem. We report the case of a 77-year-old heart failure patient with a very large mitral vegetative lesion but without fever or any other clinical or microbiological 'endocarditis criteria' except the echocardiographic findings. In this scenario, the second more likely differential diagnosis was neoformation of the mitral valve but despite an exhaustive preoperative diagnostic cardiac imaging, this hypothesis could not be excluded before surgical excision and microbiological examination of the surgical specimen...
September 20, 2016: Journal of Cardiovascular Medicine
Sebastiano Gili, Massimo Mancone, Flavia Ballocca, Walter Grosso Marra, Andrea Calcagno, Gabriella D'Ettorre, Margherita Cannillo, Fabrizio D'Ascenzo, Giancarlo Orofino, Laura Marruncheddu, Enrica Lonni, Alessandra Cinque, Francesco Vullo, Giancarlo Ceccarelli, Ilaria Vilardi, Gennaro Sardella, Vincenzo Vullo, Claudio Moretti, Francesco Fedele, Stefano Bonora, Fiorenzo Gaita
AIMS: HIV and highly active antiretroviral therapy (HAART) may affect cardiac conduction, and a higher incidence of sudden death has been recognized in HIV-positive patients. Nevertheless, predictors of prolonged corrected QT interval (cQT) have been poorly described. The aim of the study was to investigate the prevalence and predictors of long cQT in a cohort of HIV-positive patients. METHODS: Consecutive HIV-positive patients followed in a primary prevention clinic at two Italian institutions were retrospectively enrolled...
September 15, 2016: Journal of Cardiovascular Medicine
Francesco Barillà, Francesco Pelliccia, Mauro Borzi, Paolo Camici, Livio Dei Cas, Matteo Di Biase, Ciro Indolfi, Giuseppe Mercuro, Vincenzo Montemurro, Luigi Padeletti, Pasquale Perrone Filardi, Carmine D Vizza, Francesco Romeo
Definition of the optimal duration of dual anti-platelet therapy (DAPT) is an important clinical issue, given the large number of patients having percutaneous coronary intervention (PCI), the costs and risks of pharmacologic therapy, the consequences of stent thrombosis, and the potential benefits of DAPT in preventing ischaemic outcomes beyond stent thrombosis. Nowadays, the rationale for a prolonged duration of DAPT should be not only the prevention of stent thrombosis, but also the prevention of ischaemic events unrelated to the coronary stenosis treated with index PCI...
September 15, 2016: Journal of Cardiovascular Medicine
Marco Morosin, Valeria Leonelli, Rita Piazza, Matteo Cassin, Luigi Neglia, Elisa Leiballi, Eugenio Cervesato, Giulia Barbati, Gianfranco Sinagra, Gian Luigi Nicolosi
BACKGROUND AND OBJECTIVES: Bicuspid aortic valve (BAV) disease is the most common congenital cardiac malformation. The aim of the present article is to determine clinical and echocardiographic prognostic factors and provide a predictive model of outcome of a large cohort of patients with BAV. METHODS: We retrospectively enrolled 337 patients consecutively assessed for echocardiography at our Cardiology Department from 1993 to 2014. We considered aortic valve replacement, aortic surgery and cardiovascular death as a clinical combined end-point...
September 7, 2016: Journal of Cardiovascular Medicine
Pasquale Pagliaro, Claudia Penna
The heart of patients with hypertension and cardiac hypertrophy is more vulnerable to ischemia-reperfusion injury (IRI). Here we discuss the main mechanisms of IRI and possible targets for cardioprotection. In particular, we consider the viewpoint that hypertension and cardiac hypertrophy may act synergistically in increasing the predisposition to cardiovascular accidents and in worsening IRI. There is no doubt that hypertrophic hearts may be redirected to be less vulnerable to IRI. Some experimental evidences suggest that antihypertensive drugs may have beneficial effects, some of which are not directly related to hypertension-lowering effect...
September 7, 2016: Journal of Cardiovascular Medicine
Marco Centola, Stefano Lucreziotti, Sara Cazzaniga, Diego Salerno-Uriarte, Carlo Sponzilli, Stefano Carugo
Cancer is associated with a prothrombotic or hypercoagulable state. Intracoronary thrombosis is a rare and potentially life-threatening complication in cancer patients. We describe a rare case of large nonocclusive intracoronary thrombosis successfully treated by means of medical therapy.
September 7, 2016: Journal of Cardiovascular Medicine
Valentina Carubelli, Ivano Bonadei, Anna I Castrini, Elio Gorga, Alice Ravera, Carlo Lombardi, Marco Metra
BACKGROUND: Low relative lymphocyte count is an important prognostic marker in acute heart failure (AHF); however, it could be influenced by other abnormalities in white cells count. Our purpose is to evaluate if low absolute lymphocyte count (ALC) is an independent predictor of events in patients with AHF. METHODS: In a retrospective analysis, we included 309 patients with AHF, divided into two groups according to the median value of ALC at admission (1410 cells/μl)...
August 17, 2016: Journal of Cardiovascular Medicine
Patrizia Pedrotti, Angelica Peritore, Alberto Cereda, Cristina Giannattasio, Massimo Imazio
We report the incidental finding of pericardial agenesis in a patient with electrocardiographic and echocardiographic abnormalities mimicking arrhythmogenic right ventricular dysplasia. The anatomic findings were clearly depicted by cardiac magnetic resonance. The patient was asymptomatic and the clinical relevance of this finding would be raised in case a possible differential diagnosis of right heart overload should be necessary. Diagnosis may be easily suspected from the ECG and echocardiography; MRI will provide definite diagnosis...
July 27, 2016: Journal of Cardiovascular Medicine
Massimo Giammaria, Enrico Cerrato, Massimo Imazio, Antonio Curnis
The recent introduction of Magnetic Resonance-conditional implantable cardiac device has abolished the previous absolute or relative contraindications to magnetic resonance scan also in patients implanted with such devices. The present survey aimed at investigating the level of knowledge of terms and conditions for a well-tolerated use of Magnetic Resonance-conditional devices prior, during and after magnetic resonance scan among cardiologists in Piedmont (Italy). A questionnaire consisting of 32 questions was distributed to 256 cardiologists and 73 responded to the survey...
July 27, 2016: Journal of Cardiovascular Medicine
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