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Journal of Cardiovascular Medicine

Marcello Chiocchi, Marco Forcina, Daniele Morosetti, Luca Pugliese, Armando Ugo Cavallo, Daniele Citraro, Vincenzo De Stasio, Matteo Presicce, Roberto Floris, Francesco Romeo
AIM: The aim of our study is to show the importance of multislice computed tomography (CT) assessment in the overall management and diagnostic framework of transcatheter aortic valve replacement (TAVI) procedure candidates. METHODS: Between June 2015 and April 2017, 200 patients with severe aortic stenosis, not eligible for surgery, were enrolled, as defined by EuroSCORE; they were submitted to TAVI at the interventional cardiology department of the Tor Vergata Polyclinic...
July 13, 2018: Journal of Cardiovascular Medicine
Marta Petitto, Roberta Esposito, Regina Sorrentino, Maria Lembo, Federica Luciano, Anna Maria De Roberto, Lucia La Mura, Enrica Pezzullo, Silvia Maffei, Maurizio Galderisi, Patrizio Lancellotti
: Clinical presentation, diagnosis and outcomes of cardiac diseases are influenced by the activity of sex steroid hormones. These hormonal differences explain the later development of heart diseases in women in comparison with men and the different clinical picture, management and prognosis. Echocardiography is a noninvasive and easily available technique for the analysis of cardiac structure and function. The aim of the present review is to underline the most important echocardiographic differences between sexes...
July 13, 2018: Journal of Cardiovascular Medicine
Giulio La Rosa, Luigi M Biasucci, Claudia Mandolini, Isabella Massimi, Giorgia Copponi, Fabio M Pulcinelli, Filippo Crea
BACKGROUND: Multidrug resistance protein-4 (MRP4) is an ATP binding cassette membrane transporter, actively involved in the efflux of important pharmacological and physiological molecules. Recently, its over-expression has been associated with reduced aspirin (ASA) efficacy after by-pass surgery. MicroRNAs (miRNAs) are small molecules of non-coding RNA involved in the regulation of many physiological and pathophysiological pathways, are abundant in platelets, and can be modulated by several drugs...
July 13, 2018: Journal of Cardiovascular Medicine
Paolo Guccione, Arianna Di Molfetta, Danilo Montefoschi, Roberto Formigari, Maria G Gagliardi
: Aneurysmatic fistulae are rare anomalies in infancy, which may lead to cardiac failure and ischemia. The right coronary artery (RCA) angiography of a 6-month-old infant showed a dilated RCA and an aneurysmatic conal branch draining through a fistula to the right ventricle. Angiography of the left coronary artery (LCA) demonstrates afferences from the anterior descending through a diagonal branch connecting the RCA distally to the origin of the fistula and from the marginal branch of the circumflex artery anastomosed with the RCA draining into the fistula...
July 13, 2018: Journal of Cardiovascular Medicine
Amelia Spinella, Francesca Coppi, Anna Vittoria Mattioli, Federica Lumetti, Rosario Rossi, Emanuele Cocchiara, Michele Colaci, Giuseppe Boriani, Clodoveo Ferri, Carlo Salvarani, Dilia Giuggioli
No abstract text is available yet for this article.
July 11, 2018: Journal of Cardiovascular Medicine
Domenico D'Amario, Mattia Galli, Rocco Vergallo, Filippo Crea, Italo Porto
: Guidelines allowed a complex RIMA graft cannulation and the delivery of two DES throw a tortuous RIMA graft to a mid-distal left anterior descending lesion. Dissection of the RIMA graft was a complication but a successful revascularization was finally achieved.
July 11, 2018: Journal of Cardiovascular Medicine
Gabriele Dell'Era, Stefano Porcellini, Enrico Boggio, Eleonora Prenna, Miriam Gravellone, Marco Varalda, Riccardo Erbetta, Veronica Lio, Eraldo Occhetta, Paolo Marino
No abstract text is available yet for this article.
July 4, 2018: Journal of Cardiovascular Medicine
Maurizio Lunati, Giuseppe Arena, Saverio Iacopino, Roberto Verlato, Claudio Tondo, Antonio Curnis, Stefano Porcellini, Luigi Sciarra, Giulio Molon, Gaetano Senatore, Loira Leoni, Giovanni Battista Perego, Werner Rauhe, Patrizia Pepi, Maurizio Landolina
AIMS: Cryoablation is an indicated therapy for the treatment of recurrent atrial fibrillation through pulmonary vein isolation; however, the optimal time between first diagnosis of atrial fibrillation and cryoablation is still unknown. We aimed to assess the clinical efficacy and safety of early versus later treatment of patients with paroxysmal atrial fibrillation by cryoablation. METHODS: Five hundred and ten patients underwent atrial fibrillation cryoablation and were prospectively followed for at least 6 months in 43 Italian cardiology centers...
June 20, 2018: Journal of Cardiovascular Medicine
Gaetano M De Ferrari, Gian P Perna, Antonino Nicosia, Luigina Guasti, Gavino Casu, Claudio Cuccia, Francesca Picco, Caterina Strazzella, Rossana Totaro, Stefania Cercone, Laura Canullo, Martin Horack, Dominik Lautsch, Anselm K Gitt, Matteo Di Biase
AIMS: The analysis evaluated the contemporary percentage of patients with established coronary heart disease (CHD) reaching the European guidelines recommended LDL-cholesterol (LDL-C) levels of less than 70 mg/dl and the threshold required for proprotein convertase subtlisin/kexin type 9 reimbursement in Italy (100 mg/dl). It also assessed how these percentages would change in case of diffuse use of ezetimibe. METHODS: The Dyslipidemia International Study II enrolled CHD patients aged at least 18 either on lipid-lowering therapy (LLT) for at least 3 months or not on LLT at the time of the lipid profile...
June 18, 2018: Journal of Cardiovascular Medicine
Andrea Garatti, Alessandro Parolari, Alberto Canziani, Eugenio Mossuto, Andrea Daprati, Ali Abu Farah, Daniele Brugnetti, Marco Ranucci, Lorenzo Menicanti
AIMS: Despite several studies reporting a higher mortality rate for women undergoing isolated coronary artery bypass graft (CABG) surgery, this issue has not been completely clarified. The aim of the current study was to determine if sex differences in CABG surgery affect adjusted operative results and operative mortality. METHODS: Between January 2005 and December 2012, 3756 consecutive patients (3009 men and 747 women) underwent isolated CABG at our institution...
June 16, 2018: Journal of Cardiovascular Medicine
Edoardo Sciatti, Michele Senni, Carlo M Lombardi, Mauro Gori, Marco Metra
: The Prospective Comparison of Angiotensin Receptor Antagonist and Neprilysin Inhibitor with Angiotensin-Converting Enzyme Inhibitor to Determine Impact on Global Mortality and Morbidity in Heart Failure Trial has shown a reduction in the risk of death and heart failure hospitalizations with sacubitril/valsartan, compared with enalapril, in patients with heart failure and reduced ejection fraction. Guidelines now recommend the substitution of angiotensin-converting enzyme inhibitors or AT1 blockers with sacubitril/valsartan in patients with heart failure and reduced ejection fraction...
June 16, 2018: Journal of Cardiovascular Medicine
Andrea Sonaglioni, Massimo Baravelli, Antonio Vincenti, Michele Lombardo, Claudio Anzà, Gian Luigi Nicolosi
No abstract text is available yet for this article.
June 11, 2018: Journal of Cardiovascular Medicine
Nico Reinsch, Ute Ruprecht, Jochen Buchholz, Christoph Edel, Hagen Kälsch, Kars Neven
AIMS: Stroke due to atrial fibrillation has been associated with a high risk of disability and mortality. Percutaneous left atrial appendage (LAA) closure has been established as an alternative strategy for stroke prevention in patients not eligible for oral anticoagulation. The LAmbre is a novel occluder, specifically designed for LAA closure adaptive to various LAA anatomies. The aim of this study was to demonstrate feasibility and initial experience in a nonprescreened patient cohort for LAA occlusion using the novel LAmbre occluder...
June 11, 2018: Journal of Cardiovascular Medicine
Carlo Di Mario, Alessandro Mugelli, Pasquale Perrone Filardi, Giuseppe Rosano, Francesco Rossi
: Patients experiencing an acute coronary syndrome are exposed to an increased residual risk of recurrent coronary events. Dual antiplatelet therapy (DAPT) is highly effective in preventing atherothrombotic complications in patients with previous myocardial infarction and current guidelines recommend the prescription of DAPT for at least 12 months in all patients experiencing an acute event. However, recent findings demonstrated that long-term DAPT (over 12 months) is related to a better outcome in patients at high risk, suggesting the use of a long-term DAPT to achieve a better clinical outcome...
June 11, 2018: Journal of Cardiovascular Medicine
Luca Monzo, Stefano Lino, Sabrina Bencivenga, Chiara Lanzillo, Angelo Acitelli, Mauro Di Roma, Leonardo Calò
: Two-dimensional-transoesophageal-guided cardioversion is an established strategy for managing atrial arrhythmias and is commonly used to detect left atrial appendage thrombi with a high level of diagnostic confidence. In this case, we describe a challenging case of left atrial appendage mass characterization solved by a multimodality imaging approach.
June 7, 2018: Journal of Cardiovascular Medicine
Aditi Kalla, Parasuram M Krishnamoorthy, Akshaya Gopalakrishnan, Vincent M Figueredo
BACKGROUND: Cannabis for medicinal and/or recreational purposes has been decriminalized in 28 states as of the 2016 election. In the remaining states, cannabis remains the most commonly used illicit drug. Cardiovascular effects of cannabis use are not well established due to a limited number of studies. We therefore utilized a large national database to examine the prevalence of cardiovascular risk factors and events amongst patients with cannabis use. METHODS: Patients aged 18-55 years with cannabis use were identified in the National Inpatient Sample 2009-2010 database using the Ninth Revision of International Classification of Disease code 304...
June 6, 2018: Journal of Cardiovascular Medicine
Marco A Perrone, Alfredo Intorcia, Riccardo Morgagni, Massimo Marchei, Domenico Sergi, Luca Pugliese, Paolo Ferrante, Marcello Chiocchi, Mauro Borzi, Francesco Romeo
: Primary cardiac lymphoma is a rare form of non-Hodgkin lymphoma that involves the heart and can extend to the pericardium and great vessels. It is estimated that primary cardiac lymphomas account for 1.3% of primary cardiac tumors and 0.5% of all extranodal non-Hodgkin lymphomas. Definitive diagnosis is achieved with cytological and histological evaluation. Processing multimedia images is the best way to evaluate the size and extent of the tumor. Echocardiography, computerized tomography, MRI and PET are the best imaging tools in cardiac tumors...
April 27, 2018: Journal of Cardiovascular Medicine
Federica D'Auria, Maria V Polito, Gennaro Vitulano, Michele Ciccarelli, Roberta De Rosa, Alberto Gigantino, Federico Piscione, Gennaro Galasso
No abstract text is available yet for this article.
August 2018: Journal of Cardiovascular Medicine
Hans-Dirk Dungen, Renata Petroni, Michele Correale, Stefano Coiro, Francesco Monitillo, Marco Triggiani, Marta Leone, Elena-Laura Antohi, Shiro Ishihara, Chaudhry M S Sarwar, Hani N Sabbah, Maurizio Memo, Marco Metra, Javed Butler, Savina Nodari, Mihai Gheorghiade
: Despite recent advances in chronic heart failure treatment, prognosis of acute heart failure patients remains poor with a heart failure rehospitalization rate or death reaching approximately 25% during the first 6 months after discharge. In addition, about half of these patients have preserved ejection fraction for which there are no evidence-based therapies. Disappointing results from heart failure clinical trials over the past 20 years emphasize the need for developing novel approaches and pathways for testing new heart failure drugs and devices...
August 2018: Journal of Cardiovascular Medicine
Serenella Castelvecchio, Francesco Moroni, Lorenzo Menicanti
No abstract text is available yet for this article.
August 2018: Journal of Cardiovascular Medicine
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