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Archives of Medical Science: AMS

Josef Finsterer, Klaus W Preidler
No abstract text is available yet for this article.
August 2018: Archives of Medical Science: AMS
Amole O Ojo, Chhaya A Gupta, Anthon Fuisz, Zeeshan Solangi, Prakash Harikrishnan, Howard A Cooper, Julio A Panza, Wilbert S Aronow
No abstract text is available yet for this article.
August 2018: Archives of Medical Science: AMS
Gokhan Sargin, Taskin Senturk, Ongun Sahin
No abstract text is available yet for this article.
August 2018: Archives of Medical Science: AMS
Kintoko Kintoko, Xiaohui Xu, Xing Lin, Yang Jiao, Qingwei Wen, Zhaoni Chen, Jinbin Wei, Tao Liang, Renbin Huang
Introduction: Diabetes mellitus is characterized by hyperglycaemia causing changes in plasma lipoproteins, which leads to insulin resistance, secretion defects or both. The present study aimed to evaluate the ability of 2-dodecyl-6-methoxy-cyclohexa-2,5-diene-1,4-dione (DMDD) isolated from Averrhoa carambola L. roots to lower hyperglycaemia and to investigate its potential mechanism in diabetic mice. Material and methods: DMDD was isolated using a column chromatographic technique...
August 2018: Archives of Medical Science: AMS
Wenxin Xue, Yiwen Li, Jing Li, Li Yan, Fang Yang
Introduction: Few reports have mentioned the effect of etomidate on the aortas of insulin-resistant (IR) rats. In this study, we investigated the effect of etomidate on isolated IR aortas of rats, and explored its underlying mechanism. Material and methods: The IR rat model was established through feeding with a high-fructose diet. The systolic blood pressure (SBP) was measured by the tail-cuff method before grouping and at the end of the 8-week feeding; blood samples were also obtained for analysis...
August 2018: Archives of Medical Science: AMS
Roxana Postolica, Magdalena Iorga, Mihaela Savin, Doina Azoicai, Violeta Enea
Introduction: We aim to highlight the utility of this model in the analysis of the psycho-behavioral implications of family cancer, presenting the scientific literature that used Leventhal's model as the theoretical framework of approach. Material and methods: A systematic search was performed in six databases (EBSCO, ScienceDirect, PubMed Central, ProQuest, Scopus, and Web of Science) with empirical studies published between 2006 and 2015 in English with regard to the Common Sense Model of Self-Regulation (CSMR) and familial/hereditary cancer...
August 2018: Archives of Medical Science: AMS
Radoslaw Dryl, Hanna Szajewska
Introduction: Infantile colic is a common pediatric problem. The cause of infantile colic remains unclear. Treatment options are limited. Evidence suggests that probiotics might offer some benefit. The aim of the study was to systematically assess the effectiveness of probiotics supplementation in the management of infantile colic. Material and methods: MEDLINE and the Cochrane Library were searched up to April 2016 for randomized controlled trials (RCTs) evaluating the efficacy of probiotics (any well-defined strain) compared with placebo for the management of infantile colic...
August 2018: Archives of Medical Science: AMS
Paweł Kawalec, Przemysław Holko, Małgorzata Gawin, Andrzej Pilc
Introduction: Clinical studies have revealed that fixed-dose combinations (FDCs) of drugs can have a better effect on blood pressure than free-equivalent combinations (FECs). Our objectives were to perform an up-to-date assessment of the effectiveness of FDCs and FECs in antihypertensive therapy, to provide more accurate results by using a stratified meta-analysis. Material and methods: A systematic review was performed in PubMed, Web of Science, and Cochrane databases according to PRISMA guidelines...
August 2018: Archives of Medical Science: AMS
Zhong Zheng, Xiaoming Zhao, Bing Xu, Ning Yao
Introduction: Preimplantation genetic diagnosis/screening (PGD/PGS) can effectively detect chromosomal abnormalities in an embryo but only if an embryo is available. However, not all couples can obtain an embryo that is available for testing. The purpose of this study was to identify factors which might affect the formation of PGD/PGS embryos to predict the possibility of obtaining embryos that could be detected. Material and methods: In a retrospective study, we included all couples who underwent PGD/PGS at our center from January 2015 to December 2016...
August 2018: Archives of Medical Science: AMS
Wang Kuan-Hong, Li Bai-Zhou
Introduction: Redox signaling initiates pathogenesis of neuronal degeneration. Plumbagin is a potential antioxidant with anti-inflammatory, anti-cancer and radio sensitizing properties. In the present study, we aimed to determine the protective role of plumbagin against H2 O2 -induced neurotoxicity in PC12 cells by determining nuclear factor κB (NF-κB) and nuclear factor E2-related factor 2 (Nrf-2) pathways. Material and methods: We analyzed oxidative stress by determining reactive oxygen species (ROS) and nitrite levels, and antioxidant enzyme activities...
August 2018: Archives of Medical Science: AMS
Hualin Ma, Shuyan Zhang, Ying Xu, Rongrong Zhang, Xinzhou Zhang
Introduction: To analyze the microRNA expression of tumor necrosi factor α (TNF-α) stimulated mesenchymal stem cells (MSCs) and exosomes from their culture supernatant. Material and methods: TNF-α (20 ng/ml) was used to stimulate MSCs, which were then regarded as TNF-α cells (TC), while unstimulated cells were the normal control cells (NCC). MSCs and their culture supernatant were harvested after 48 h. Subsequently, exosomes were isolated from culture supernatants with ExoQuick-TC and were divided into two groups, TNF-α exosomes (TE) and normal control exosomes (NCE)...
August 2018: Archives of Medical Science: AMS
Shan Shi, Lianhua Jin, Sai Zhang, Haibo Li, Bo Zhang, Meihua Sun
Introduction: Pediatric asthma has remained a health threat to children in recent years. The abnormal proliferation of airway smooth muscle (ASM) cells contributes to airway remodeling during development of asthma. MicroRNAs (miRNAs) are critical regulators of ASM cell proliferation during airway remodeling. miR-590-5p has been reported to regulate cell proliferation in various cell types. However, it remains unclear whether miR-590-5p regulates ASM cell proliferation. In this study, we aimed to investigate the potential role of miR-590-5p in regulating fetal ASM cell proliferation in vitro stimulated by platelet-derived growth factor (PDGF)...
August 2018: Archives of Medical Science: AMS
Patrick Weber, Florian Schmidutz, Andreas Ficklscherer, Arnd Steinbrück, Volkmar Jansson, Hans Roland Dürr
Introduction: Sexuality is an important factor in quality of life (QoL) and was reported to improve after total joint arthroplasty (TJA). However, one study group found evidence regarding a high rate of impaired erectile function of about 20% in male patients after TJA. As erectile dysfunction is a serious matter of concern and there are no data explaining this observation sufficiently, the purpose of this study was to revaluate the erectile function in patients after TJA. Material and methods: All consecutive male patients scheduled for TJA were enrolled in this prospective study...
August 2018: Archives of Medical Science: AMS
Amela Dervišević, Halima Resić, Šekib Sokolović, Nermina Babić, Nesina Avdagić, Asija Začiragić, Amela Bečiragić, Almir Fajkić, Orhan Lepara, Almira Hadžović-Dzuvo
Introduction: Leptin is a cytokine-like hormone which has a complex role in inflammation. However, the importance of leptin in the pathogenesis of rheumatoid arthritis (RA) is far from being fully elucidated. The aim of the study was to determine serum leptin levels in RA patients and to evaluate whether there is an association between disease activity, anthropometric indices and leptin levels. Material and methods: This hypothesis-generating study included 55 RA patients and 25 matched healthy subjects...
August 2018: Archives of Medical Science: AMS
Grażyna Bączyk, Katarzyna Kozłowska
Introduction: The aim of this study was to assess quality of life among patients with rheumatoid arthritis (RA) treated as outpatients. The specific question was: does the quality of life of RA patients depend on demographic variables and clinical variables? Material and methods: The study included 240 patients with RA recruited from outpatients. To assess quality of life, the Arthritis Impact Measurement Scales 2 was applied. Clinical tests: VAS, Morning Stiffness, Grip Strength, Richie Articular Index...
August 2018: Archives of Medical Science: AMS
Masoumeh Gity, Ali Arabkheradmand, Elham Taheri, Madjid Shakiba
Introduction: Breast magnetic resonance imaging (BMRI) has been identified as a valuable modality in the diagnosis of breast cancer and monitoring the response to chemotherapy. The aim of this study was to evaluate the relative importance of different descriptors of breast masses in contrast-enhanced breast MRI. Material and methods: In a database of pathologically proven breast lesions, in total 433 masses in 312 patients detected by contrast-enhanced breast MRI were selected...
August 2018: Archives of Medical Science: AMS
Jian-Hua Lei, Xing Gong, Xin-Qiang Xiao, Zi Chen, Feng Peng
Introduction: Few large-scale investigations on genotype (GT) distribution of hepatitis C virus (HCV) in Hunan Province, China, are reported. Material and methods: We recruited all of the 952 patients in the census register of Hunan Province who were first diagnosed with HCV infection in the Second Xiangya Hospital, Central South University in 2014-2016. HCV genotypes were surveyed. The genotype distribution pattern was compared with those of the neighboring regions in China...
August 2018: Archives of Medical Science: AMS
Hao Cai, Jiefei Bai, Jian Li, Huacong Cai, Minghui Duan, Xinxin Cao, Miao Chen, Daobin Zhou, Wei Zhang
Introduction: Lenalidomide is an effective therapy of POEMS syndrome. However, there is concern that exposure to lenalidomide may reduce the efficiency of blood cell collection in persons who may eventually receive an autotransplant. We studied the impact of lenalidomide therapy on subsequent blood cell mobilization and collection including frequency of blood CD34+ cells and CXCR4 expression before and after mobilization with cyclophosphamide and granulocyte-colony stimulating factor (G-CSF)...
August 2018: Archives of Medical Science: AMS
Marzena Dębska, Małgorzata Uhrynowska, Katarzyna Guz, Izabella Kopeć, Elżbieta Lachert, Agnieszka Orzińska, Piotr Kretowicz, Jolanta Antoniewicz-Papis, Romuald Dębski, Magdalena Łętowska, Anne Husebekk, Ewa Brojer
Introduction: Pregnant women negative for human platelet antigen 1a (HPA-1a) are at risk of alloimmunization with fetal HPA-1a antigen inherited from the father, and their offspring may develop fetal and neonatal alloimmune thrombocytopenia (FNAIT). The aim of this study was to analyze the frequency of HPA-1a alloimmunization in pregnant Polish women, the feasibility of using maternal platelets for intrauterine transfusions in women subjected to diagnostic fetal blood sampling (FBS) and to discuss potential consequences of alloimmunization...
August 2018: Archives of Medical Science: AMS
Nermine El-Maraghy, Mona S Ghaly, Omar Dessouki, Samah Ismail Nasef, Lobna Metwally
Introduction: T regulatory cells (Treg) play an important role in the maintenance of immune cell homeostasis, as it has been reported that CD4+CD25+ T cells suppress the auto-reactive responses in autoimmune diseases such as systemic lupus erythematosus (SLE). The clinical significance of the recently identified population of CD4+CD25-Foxp3+ T cells and whether they are associated with particular organ involvement is still not clear. So, the aim of our study was to evaluate the presence of CD4+CD25-Foxp3+ cells in SLE patients in comparison to healthy controls and to determine whether their frequency is associated with disease activity and particular clinical manifestations in these SLE patients...
August 2018: Archives of Medical Science: AMS
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