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Archives of Medical Science: AMS

Marina Attanasi, Marianna Immacolata Petrosino, Paola Irma Guidone, Daniele Rapino, Laura Comegna, Nadia Rossi, Annalisa Blasetti, Francesco Chiarelli
No abstract text is available yet for this article.
January 2018: Archives of Medical Science: AMS
Carmen K M Cheung, Man Fai Law, Ka Tak Wong, Mark T K Tam, Kai Ming Chow
No abstract text is available yet for this article.
January 2018: Archives of Medical Science: AMS
Piotr Bienias, Anna Kostera-Pruszczyk, Maria Miszczak-Knecht, Michał Ciurzyński, Piotr Pruszczyk
No abstract text is available yet for this article.
January 2018: Archives of Medical Science: AMS
Edyta Szymańska, Sylwia Szymańska, Grażyna Truszkowska, Elżbieta Ciara, Maciej Pronicki, Yoon S Shin, Teodor Podskarbi, Alina Kępka, Mateusz Śpiewak, Rafał Płoski, Zofia T Bilińska, Dariusz Rokicki
No abstract text is available yet for this article.
January 2018: Archives of Medical Science: AMS
J Francis Borgio, Sayed AbdulAzeez, Ahmed M Al-Muslami, Zaki A Naserullah, Sana Al-Jarrash, Ahmed M Al-Suliman, Mohammed S Al-Madan, Amein K Al-Ali
Introduction: Elevated HbA2 (hemoglobin A2) level is considered the most reliable hematological parameter for the detection of β-thalassemia carriers. However, some carriers are difficult to recognize because the level of HbA2 is not in the distinctive carrier range, i.e. 4.0-6.0%; instead, some carriers have HbA2 levels between normal and carrier levels, i.e. borderline HbA2 (HbA2 = 3.1-3.9%). Studies have shown that variations in the erythroid Krüppel-like factor (KLF1) gene lead to borderline HbA2 in β-thalassemia carriers from various populations...
January 2018: Archives of Medical Science: AMS
Sailaja Polavarapu, Bilikere S Dwarakanath, Undurti N Das
Introduction: This study was conducted to examine whether bleomycin-induced growth inhibitory action on human neuroblastoma cells (IMR-32) is influenced by anti-inflammatory metabolites of polyunsaturated fatty acids (PUFAs): lipoxin A4 (LXA4), resolvin D1 and protectin D1 in vitro. Material and methods: The in vitro study was conducted using monolayer cultures of exponentially growing IMR-32 cells. The effects of various PUFAs and eicosanoids and anti-inflammatory metabolites of PUFAs such as lipoxin A4 (LXA4), resolvin D1 and protectin D1 on the growth of IMR-32 cells and human lymphocytes in vitro were investigated...
January 2018: Archives of Medical Science: AMS
Tomasz Podgórski, Grażyna Szmyt, Agnieszka Szmyt, Joanna Gronek, Roman Celka, Piotr Gronek
Introduction: One reason for the limited effectiveness of the available smoking cessation methods is the fact that the causes of tobacco addiction have not been adequately explained yet. Numerous anti-smoking programs aimed at women involve intense physical activity. The goal of the study was to evaluate the effectiveness of health training for smoking cessation by young women in connection with the dopamine receptor gene (D4DR) in their genetic profile. Material and methods: Forty-eight adult female smokers were randomly assigned to: 1) a concentration training group, or 2) an aerobic and concentration training group...
January 2018: Archives of Medical Science: AMS
Anna Brzęk, Markus Strauss, Bianca Przybylek, Tarja Dworrak, Birgit Dworrak, Roman Leischik
Introduction: Apart from many positive changes associated with technical civilization, there are also - from the health point of view - some threats. The reduction in the level of physical activity is one of them. The aim of the study was to investigate whether there are any relationships between children's physical activity and behaviors, and to assess the impact of the adults' activity on their children's habits. Material and methods: The study involved a group of 340 children aged 7-12 years (mean age: 9...
January 2018: Archives of Medical Science: AMS
Joanna Mazur, Monika Szkultecka-Dębek, Anna Dzielska, Mariola Drozd, Agnieszka Małkowska-Szkutnik
Introduction: The Cantril Scale (CS) is a simple visual scale which makes it possible to assess general life satisfaction. The result may depend on the health, living, and studying conditions, and quality of social relations. The objective of this study is to identify key factors influencing the CS score in Polish adolescents. Material and methods: The survey comprised 1,423 parent-child pairs (54% girls; age range: 10-17; 67.3% urban inhabitants; 89.4% of parents were mothers)...
January 2018: Archives of Medical Science: AMS
Mehmet Enes Gokler, Necati Bugrul, Ahu Ozturk Sarı, Selma Metintas
Introduction: The objective was to assess the validity of self-reported body weight and height and the possible influence of self-perception of body mass index (BMI) status on the actual BMI during the adolescent period. Material and methods: This cross sectional study was conducted on 3918 high school students. Accurate BMI perception occurred when the student's self-perception of their BMI status did not differ from their actual BMI based on measured height and weight...
January 2018: Archives of Medical Science: AMS
Ewa Z Gieysztor, Anna M Choińska, Małgorzata Paprocka-Borowicz
Introduction: Retained primitive reflexes can disturb natural development and involve difficulties in social and educational children's life. They can also impact on psychomotor development. Mature responses in a child's psychomotor progress can only occur if the central nervous system itself has reached maturity. The process consist the transition made from brain stem reflex response to cortically controlled response. This study define the occurrence of primitive reflexes in healthy 4-6 years old children and analyze the impact of survived primitive reflexes on psychomotor development...
January 2018: Archives of Medical Science: AMS
Anamaria Todoran Butilă, Ancuta Zazgyva, Anca Ileana Sin, Elisabeta Racoș Szabo, Mariana Cornelia Tilinca
Introduction: This case-control study aimed to assess two single nucleotide polymorphisms of the gene encoding the GABRG2 protein - GABRG2 (3145 G>A) and GABRG2 rs 211037 Asn196Asn (C588T) - in a cohort of pediatric patients from Romania, and evaluate their possible impact on drug-resistant forms of generalized epilepsy and recurrent febrile seizures. Material and methods: One hundred and fourteen children with idiopathic generalized epilepsy (group 1) or febrile seizures (group 2) were compared to 153 controls...
January 2018: Archives of Medical Science: AMS
Aysenur Bahadir, Erol Erduran, Orhan Değer, Yelda Birinci, Ahmet Ayar
Introduction: Dyshomeostasis of essential trace elements including iron and copper plays a key role in the pathogenesis of a myriad of serious conditions including iron deficiency (ID) anemia, in which impaired cellular energy metabolism is prominent. Although experimental studies documented decreased activity of cytochrome c oxidase (CytOx) in ID, there are not enough clinical data. The present study was conducted to determine serum copper levels and activity of mitochondrial CytOx in isolated lymphocytes of patients with iron deficiency...
January 2018: Archives of Medical Science: AMS
Piotr Buda, Piotr Gietka, Janusz B Książyk, Maciej Machaczka
Introduction: Secondary hemophagocytic lymphohistiocytosis (sHLH) is a life-threatening syndrome of severe hyperinflammation which is often triggered by infection or autoimmune disease (macrophage activation syndrome - MAS). The aim of our study was to assess the frequency of sHLH/MAS in children treated in our institution and to compare the effectiveness of various therapeutic interventions. Material and methods: Between 2005 and 2013, 24 children (age: 1-17 years) were consecutively treated for sHLH/MAS...
January 2018: Archives of Medical Science: AMS
Marianna I Petrosino, Alessandra Scaparrotta, M Loredana Marcovecchio, Daniele Panichi, Daniele Rapino, Marina Attanasi, Paola Di Filippo, Sabrina Di Pillo, Francesco Chiarelli
Introduction: Egg allergy is one of the most common food allergies in children. Egg white, including ovomucoid (OVM or Gal d 1) and ovalbumin (OVA or Gal d 2), is the major source of allergens. The aim of this study was to assess the role of Gal d 1 and Gal d 2 in predicting the risk of anaphylaxis caused by eggs in children, and to compare this new diagnostic tool with established methods of allergen-specific IgE detection. Material and methods: One hundred and forty-eight children were divided into 2 groups according to a positive (group A, 33 children) or negative (group B, 115 children) history of anaphylaxis after ingestion/contact with eggs...
January 2018: Archives of Medical Science: AMS
Joanna Jerzyńska, Włodzimierz Stelmach, Błażej Rychlik, Paweł Majak, Daniela Podlecka, Katarzyna Woicka-Kolejwa, Iwona Stelmach
Introduction: Vitamin D deficiency has been proposed as a potential contributing factor in patients with allergic diseases. We compared the clinical and immunological effects of vitamin D supplementation to placebo during the pollen season in children with allergic rhinitis. Material and methods: Thirty-eight children aged 5-12, sensitive to grass pollen, participated in a prospective, randomized, double-blind, placebo-controlled trial. Children received either vitamin D 1000 IU daily supplementation or placebo...
January 2018: Archives of Medical Science: AMS
Sherein Abdelhamid Shalaby, Nesrein Mosad Handoka, Rasha Emad Amin
Introduction: In humans, vitamin D has been shown to play a role in infectious diseases, but its association with acquisition and a complicated course of febrile urinary tract infections (UTIs) has not been investigated. We aimed to investigate the association between 25-hydroxyvitamin D (25(OH)D 3 ) levels and the risk of first time febrile UTI in children. Material and methods: This prospective case-control study included 50 children with first febrile UTI, with no risk factors for UTI, and 50 age- and sex-matched healthy siblings as controls...
January 2018: Archives of Medical Science: AMS
Andrzej Wędrychowicz, Przemysław Tomasik, Andrzej Zając, Krzysztof Fyderek
Introduction: Interleukin-1β (IL-1β), interleukin-1 receptor antagonist (IL-1ra) and interleukin-6 (IL-6) contribute to the pathogenesis of ulcerative colitis (UC). The aim of our study was to evaluate the serum and stool IL-1β, IL-1ra and IL-6 concentrations as potential prognostic factors in children with UC. Material and methods: Thirty-eight children with UC (20 active, 18 inactive) and 14 healthy controls were prospectively included in the study. IL-1β, IL-1ra and IL-6 concentrations were measured in serum and stool supernatants at inclusion to the study using ELISA immunoassays...
January 2018: Archives of Medical Science: AMS
Raida S Yahya, Soha I Awad, Nadeem Kizilbash, Hatim A El-Baz, Gehan Atia
Introduction: Infection by intestinal parasites in childhood may be the main cause of many health-related problems in developed countries such as anemia, anorexia, loss of appetite, retarded growth and development. The aim of the present study was to assess the effect of different intestinal parasites on white adipose tissue hormones. Material and methods: Eighty-one children infected by different parasites and 35 apparently healthy children were enrolled in this study...
January 2018: Archives of Medical Science: AMS
Oana Belei, Andreea Dobrescu, Rodica Heredea, Emil Radu Iacob, Vlad David, Otilia Marginean
Introduction: Celiac disease (CD) is defined by gluten-induced immune-mediated enteropathy, affecting approximately 1% of the genetically predisposed population. The immunologic response to gluten causes characteristic intestinal alterations with gradual development. Histologic recovery of intestinal architecture was reported to occur within 6-12 months after starting a gluten-free diet, simultaneously with clinical remission. The aim of this study was to assess the rate and timing of histologic recovery among children with CD on a gluten-free diet, diagnosed and followed in an academic referral pediatric center during a 10-year period...
January 2018: Archives of Medical Science: AMS
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