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Archives of Medical Science: AMS

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https://www.readbyqxmd.com/read/28261308/clinical-response-to-calcium-channel-blockers-in-a-hemodynamically-unstable-patient-with-reactive-idiopathic-pulmonary-arterial-hypertension
#1
Grzegorz Kopec, Marcin Waligóra, Anna Tyrka, Monika Komar, Natasza Herman, Piotr Podolec
No abstract text is available yet for this article.
March 1, 2017: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/28261307/myocardial-metastasis-from-cervical-carcinoma-causing-left-anterior-descending-coronary-artery-occlusion-and-st-segment-elevation-myocardial-infarction
#2
Gabriel Wagman, Wilbert S Aronow, Howard A Cooper
No abstract text is available yet for this article.
March 1, 2017: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/28261306/recombinant-factor-viia-for-variceal-bleeding-in-liver-cirrhosis-still-only-a-hope
#3
Xingshun Qi, Chun Ye, Xiaozhong Guo
No abstract text is available yet for this article.
March 1, 2017: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/28261305/the-effect-of-osteoprotegerin-on-implant-osseointegration-in-ovariectomized-rats
#4
Yiming Liu, Jing Hu, Biao Liu, Xiliang Jiang, Yunfeng Li
INTRODUCTION: Osteoprotegerin (OPG), the endogenous inhibitor of RANKL, prevents or reverses bone loss in a variety of preclinical models of bone disease. Preclinical studies indicate that osteoporosis significantly impairs implant fixation. This study aims to investigate the role of OPG in implant osseointegration in ovariectomized rats. MATERIAL AND METHODS: Twelve weeks after bilateral ovariectomy, each rat accepted two titanium screws in the proximal tibiae...
March 1, 2017: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/28261304/the-influence-of-different-footprint-preparation-techniques-on-tissue-regeneration-in-rotator-cuff-repair-in-an-animal-model
#5
Andreas Ficklscherer, Michaela Serr, Thomas Loitsch, Thomas R Niethammer, Matthias Lahner, Matthias F Pietschmann, Peter E Müller
INTRODUCTION: Rotator cuff tears are common diseases of the upper extremity. There are no recommendations to the surgeon on how to prepare the footprint to ensure optimal tendon-to-bone healing. However, biologic augmentation using stem cells and growth factors is considered to encourage the healing process of the tendon. The aim of the study was to investigate the biomechanical and histological outcome of different footprint preparations in rotator cuff repair. MATERIAL AND METHODS: One hundred and eighty-nine Sprague-Dawley rats were randomly assigned to either spongialization, radiofrequency ablation or an untreated control group...
March 1, 2017: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/28261303/stimulation-of-%C3%AE-adrenergic-receptors-plays-a-protective-role-via-increased-expression-of-raf-1-and-pdx-1-in-hyperglycemic-rat-pancreatic-islet-rin-m5f-cells
#6
Sher Zaman Safi, Rajes Qvist, Gracie Ong, Hamed Karimian, Muhammad Imran, Ikram Shah
INTRODUCTION: It is a widely held view that a progressive reduction of beta-cell mass occurs in the progression of diabetes. RAF-1 kinase and pancreas duodenal homeobox 1 (PDX-1) are major factors that promote survival of cells and maintain normal insulin functions. In this study we investigated the effect of a β-adrenergic receptor agonist and antagonist on RAF-1 and PDX-1, and their respective effects on apoptosis and insulin release in RIN-m5F cells. MATERIAL AND METHODS: RIN-m5F cells were cultured in normal (5 mM) and high (25 mM) glucose to mimic diabetic conditions, followed by treatment with 5 µM, 10 µM and 20 µM of isoproterenol and isoproterenol + propranolol for 6, 12 and 24 h...
March 1, 2017: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/28261302/the-vitamin-d-analogue-paricalcitol-attenuates-hepatic-ischemia-reperfusion-injury-through-down-regulation-of-toll-like-receptor-4-signaling-in-rats
#7
Min Sung Kim, Soyoung Lee, Namhee Jung, Kiho Lee, Jinwoo Choi, Sang-Hoon Kim, Jinhyun Jun, Won-Mee Lee, Yeonsoo Chang, Donghee Kim
INTRODUCTION: Recent studies have revealed that vitamin D and its synthetic analogues have a protective effect on experimental ischemia/reperfusion (I/R) models in several organs, but little is known about its effect on the liver. The aim of this study was to evaluate the beneficial effects of vitamin D in a model of liver I/R in rats, focusing on Toll-like receptor (TLR) 4 signaling, which has been shown to be involved in I/R injury. MATERIAL AND METHODS: Twenty-four male Wistar rats were randomized into four groups: Saline + Sham, Saline + I/R, Paricalcitol + Sham, and Paricalcitol + I/R...
March 1, 2017: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/28261301/cardiomyocyte-mitochondria-as-targets-of-humoral-factors-released-by-remote-ischemic-preconditioning
#8
Nilguen Gedik, Leonardo Maciel, Christiane Schulte, Andreas Skyschally, Gerd Heusch, Petra Kleinbongard
INTRODUCTION: Remote ischemic preconditioning (RIPC) reduces myocardial infarct size, and protection can be transferred with plasma to other individuals, even across species. Mitochondria are the end-effectors of cardioprotection by local ischemic conditioning maneuvers. We have now analyzed mitochondrial function in response to RIPC. MATERIAL AND METHODS: Plasma from pigs undergoing placebo or RIPC (infarct size reduction by 67% in RIPC pigs compared to placebo) was transferred to isolated perfused rat hearts subjected to 30 min global ischemia followed by 120 min reperfusion for infarct size measurement...
March 1, 2017: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/28261300/the-impact-of-the-polish-mass-breast-cancer-screening-program-on-prognosis-in-the-pomeranian-province
#9
Piotr Woźniacki, Jarosław Skokowski, Krzystof Bartoszek, Anna Kosowska, Leszek Kalinowski, Janusz Jaśkiewicz
INTRODUCTION: Mammographic screening results in diagnosis of less advanced breast cancer (BC). A meta-analysis of randomized clinical trials confirmed that BC screening reduces mortality. In 2007, the National Breast Cancer Screening Program (NBCSP) was established in Poland with the crucial aim of reducing mortality from BC. The purpose of this study was to assess the impact of participation in the NBCSP on prognosis. MATERIAL AND METHODS: A single institution, non-randomized retrospective study was undertaken...
March 1, 2017: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/28261299/health-behaviors-health-definitions-sense-of-coherence-and-general-practitioners-attitudes-towards-obesity-and-diagnosing-obesity-in-patients
#10
Monika Bąk-Sosnowska, Violetta Skrzypulec-Plinta
INTRODUCTION: Physicians' attitudes towards health may influence the motivation of patients for constructive health behaviors. The purpose of this study was to evaluate general practitioners (GP) attitudes towards health and to determine factors affecting diagnosis of obesity in their patients. MATERIAL AND METHODS: We examined 250 GPs. The average age was 53.55 ±10.57 years. We used methods examining: health behaviors (IZZ), the sense of coherence (SOC-29), the individual meaning of health (LZK), and attitude toward obesity (own questionnaire)...
March 1, 2017: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/28261298/fas-fasl-gene-polymorphisms-in-turkish-patients-with-chronic-myeloproliferative-disorders
#11
Fusun Gediz Ozdemirkiran, Sinem Nalbantoglu, Zafer Gokgoz, Bahriye Kadriye Payzin, Filiz Vural, Seckin Cagirgan, Afig Berdeli
INTRODUCTION: Chronic myeloproliferative disorders (CMPD) are chronic myeloid hematological disorders, characterized by increased myeloid cell proliferation and fibrosis. Impaired apoptotic mechanisms, increased cell proliferation, uncontrolled hematopoietic cell proliferation and myeloaccumulation may contribute to the pathogenesis of CMPD. The aim of our study was to show the possible role of FAS/FASL gene polymorphisms in CMPD pathogenesis and investigate the association with clinical parameters and susceptibility to disease...
March 1, 2017: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/28261297/comparison-of-prognostic-value-of-n-terminal-pro-brain-natriuretic-peptide-in-septic-and-non-septic-intensive-care-patients
#12
Namik Ozcan, Ayse Ozcan, Cetin Kaymak, Hulya Basar, Mustafa Kotanoglu, Bektas Kose
INTRODUCTION: The aim of this study is to compare the prognostic value of N-terminal pro-brain natriuretic peptide (NT-proBNP) levels in septic and non-septic intensive care patients. MATERIAL AND METHODS: Fifty consecutive patients admitted to the intensive care unit (ICU) were enrolled in either the septic or non-septic group according to the criteria in the International Sepsis Definitions Conference in 2001. Demographic and clinical data, procalcitonin and lactate levels at admission, and death within 28 days were registered...
March 1, 2017: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/28261296/gastrointestinal-disorders-next-to-respiratory-infections-as-leading-symptoms-of-x-linked-agammaglobulinemia-in-children-34-year-experience-of-a-single-center
#13
Malgorzata Pac, Ewa A Bernatowska, Jarosław Kierkuś, Józef P Ryżko, Joanna Cielecka-Kuszyk, Teresa Jackowska, Bożena Mikołuć
INTRODUCTION: Respiratory tract infections constitute the most frequent manifestation of X-linked agammaglobulinemia (XLA). There are not many papers elucidating gastrointestinal (GI) disorders, including inflammatory bowel disease (IBD), in such patients. The aim of the study was to evaluate the occurrence of gastrointestinal disorders and IBD compared to respiratory tract infections in XLA individuals. MATERIAL AND METHODS: Of 1563 patients with primary immunodeficiencies diagnosed in the Department of Immunology, the Children's Memorial Health Institute (CMHI), 66 boys had a provisional diagnosis of agammaglobulinemia...
March 1, 2017: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/28261295/pretreatment-neutrophil-to-lymphocyte-ratio-in-peripheral-blood-was-associated-with-pulmonary-tuberculosis-retreatment
#14
Yongmei Yin, Shougang Kuai, Jun Liu, YingYing Zhang, Zhongbao Shan, Lan Gu, Qiusheng Huang, Hao Pei, Jun Wang
INTRODUCTION: The neutrophil-to-lymphocyte ratio (NLR) is a readily available biomarker associated with recurrence and survival in various diseases. The objective of this study was to investigate the relationship between NLR and pulmonary tuberculosis (PTB) retreatment. MATERIAL AND METHODS: This was a case-control study that included 306 newly diagnosed cases of PTB in the clinical database of the Infectious Hospital of Wuxi from December 2009 to December 2011...
March 1, 2017: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/28261294/influence-of-intraoperative-positive-end-expiratory-pressure-level-on-pulmonary-complications-in-emergency-major-trauma-surgery
#15
Thomas Stueber, Jan Karsten, Nikolas Voigt, Michaela Wilhelmi
INTRODUCTION: Pulmonary complications have a major impact on the morbidity and mortality of critically ill patients with multiple trauma. Intraoperative protective ventilation with low tidal volume may prevent lung injury and infection, whereas the role of positive end-expiratory pressure (PEEP) levels is unclear. The aim of this study was to evaluate the influence of different intraoperative PEEP levels on incidence of pulmonary complications after emergency trauma surgery. MATERIAL AND METHODS: We retrospectively analysed data of multiple trauma patients who underwent emergency surgery within 24 h after injury in our level I trauma centre (n = 86)...
March 1, 2017: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/28261293/clinical-and-histopathological-characteristics-of-patients-with-incidental-and-nonincidental-thyroid-cancer
#16
Krzysztof Kaliszewski, Dorota Diakowska, Marta Strutyńska-Karpińska, Beata Wojtczak, Paweł Domosławski, Waldemar Balcerzak
INTRODUCTION: Thyroid nodules (TNs) are a common pathology. Their prevalence increases with age. Some of them are suspected of malignancy and qualified for surgery. Sometimes their malignant nature is detected incidentally after a surgical procedure. The aim of the study is to analyze clinical and histopathological characteristics of patients with incidental and nonincidental thyroid carcinoma (ITC vs. NITC). MATERIAL AND METHODS: The case records of 3,241 patients with solitary and multiple TNs who were treated consecutively between 2008 and 2014 were analyzed retrospectively...
March 1, 2017: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/28261292/epicardial-fat-thickness-and-oxidative-stress-parameters-in-patients-with-subclinical-hypothyroidism
#17
Ali Aydogdu, Emel Yigit Karakas, Emre Erkus, İbrahim Halil Altıparmak, Emin Savık, Turgay Ulas, Tevfik Sabuncu
INTRODUCTION: Thyroid disorders are known to be a risk factor for cardiovascular diseases. Epicardial fat thickness (EFT) and oxidative stress are also believed to be major risk factors for cardiovascular events. The aim of this study was to evaluate the possible relationship between oxidative stress parameters and EFT in patients with subclinical hypothyroidism (SCH). MATERIAL AND METHODS: A total of 60 individuals (30 patients with SCH and 30 healthy controls) were recruited for the study...
March 1, 2017: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/28261291/the-prevalence-and-impact-of-brucellosis-in-patients-with-hepatitis-delta-virus-infection-inside-the-brucella-outbreak-with-cirrhosis
#18
Burak Suvak, Ahmet Cumhur Dulger, Ozlem Suvak, Aysun Özel Yesilyurt, Bilge Gultepe, Huseyin Guducuoglu
INTRODUCTION: Hepatitis D virus (HDV) infection is a serious health problem leading to cirrhosis and hepatocellular carcinoma (HCC). Despite evidence that zoonotic infections are associated with end-stage liver disease, brucellosis in patients with delta hepatitis related to liver disease has not been well characterized. So, we examined this relationship using recent hospital-based data. MATERIAL AND METHODS: We analyzed data from 96 delta hepatitis patients (mean age: 52...
March 1, 2017: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/28261290/prediction-of-oesophageal-varices-in-patients-with-primary-biliary-cirrhosis-by-non-invasive-markers
#19
Lili Gao, Fanping Meng, Jun Cheng, Hanwei Li, Jun Han, Weihui Zhang
INTRODUCTION: Preliminary data suggested that non-invasive methods could be useful to assess presence of oesophageal varices (OV) in liver cirrhosis. The primary objectives were to investigate non-invasive markers for diagnosing and grading OV in patients with primary biliary cirrhosis. MATERIAL AND METHODS: This study included a total of 106 consecutive treatment-naive patients with primary biliary cirrhosis (PBC). Results of physical examination, blood tests, and abdominal ultrasound scan (USS) were measured...
March 1, 2017: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/28261289/nutritional-risk-screening-2002-and-asa-score-predict-mortality-after-elective-liver-resection-for-malignancy
#20
Thomas Zacharias, Nelio Ferreira
INTRODUCTION: The aim of the study was to evaluate whether Nutritional risk screening 2002 (NRS 2002) at hospital admission may predict postoperative mortality and complications within 90 days after elective liver resection for malignancy. MATERIAL AND METHODS: A retrospective cohort study of a prospective database was performed. Two-hundred and three patients with elective liver resection for malignancy between 9 November 2007 and 27 May 2014 were included. Clinical data, NRS 2002, surgical procedures and histology were recorded...
March 1, 2017: Archives of Medical Science: AMS
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