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Hellenic Journal of Nuclear Medicine

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https://www.readbyqxmd.com/read/28426840/multimodality-multiparametric-brain-tumors-evaluation
#1
REVIEW
Vasiliki Tsitsia, Patricia Svolou, Eftichia Kapsalaki, Kyriaki Theodorou, Katerina Vassiou, Varvara Valotassiou, Panagiotis Georgoulias, Ioannis Fezoulidis, Ioannis Tsougos
Brain tumors represent a vast group of lesions, originating from different neuronal cells with different degrees of aggressiveness. Despite some technological advances either pre or post-treatment, these tumors may share similar imaging findings and properties, rendering diagnosis/prognosis, an ambiguous process. Gadolinium-enhanced magnetic resonance imaging remains the gold standard for providing detailed morphologic information, but presents several limitations due to the overlap of findings, in cases such as progressive tumor and post-radiation related effects...
January 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/28426839/medical-history-in-the-hellenic-journal-of-nuclear-medicine
#2
EDITORIAL
Andreas Otte
The Hellenic Journal of Nuclear Medicine is about to celebrate its 20th anniversary end of 2017. On board of the editorial team since 2003, this journal has influenced me like a good friend over the many past years. From time to time, the journal has published interesting and valuable historical notes. They show that nuclear medicine has a history and that medicine is its basis. They also teach us today, and some of the ancient perspectives and approaches are still valid. The reader of HJNM may be interested in these historical contributions, as they are timeless...
January 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/28315919/a-rare-adult-renal-neuroblastoma-better-imaged-by-18-f-fdg-than-by-68-ga-dotanoc-in-the-pet-ct-scan
#3
COMPARATIVE STUDY
Tarun Kumar Jain, Sharwan Kumar Singh, Ashwani Sood, Abhiram Gj Ashwathanarayama, Rajender Kumar Basher, Jaya Shukla, Bhagwant Rai Mittal
Primary renal neuroblastoma is an uncommon tumor in children and extremely rare in adults. We present a case of a middle aged female having a large retroperitoneal mass involving the right kidney with features of neuroblastoma on pre-operative histopathology. Whole-body fluorine-18-fluoro-deoxyglucose positron emission tomography ((18)F-FDG PET/CT) and (68)Ga-dotanoc PET/CT scans performed for staging and therapeutic potential revealed a tracer avid mass replacing the right kidney and also pelvic lymph nodes...
January 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/28315918/fluorrine-18-fluorodeoxyglucose-positron-emission-tomography-computed-tomography-of-adult-liver-langerhans-cell-histiocytosis
#4
Hengshan Ji, Jiang Wu, Guifen Yang, Chuanjin Sun, Hong Zhu, Longjiang Zhang
OBJECTIVE: Adult liver Langerhans cell histiocytosis (LCH) is an extremely rare desease. This paper reports a 40 years old male patient who was diagnosed as liver LCH though ultrasound-guided liver biopsy. The initial Fluorrine-18- fluorodeoxyglucose positron emission tomography/ computed tomography ((18)F-FDG PET/CT) showed multiple nodular low-density lesions in liver without obvious elevated (18)F-FDG uptake. Four years later, the follow-up (18)F-FDG PET/CT showed the liver multiple lesions with slightly elevated (18)F-FDG uptake...
January 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/28315917/a-pediatric-hypophosphatemic-rickets-on-mri-99m-tc-mdp-bone-scan-and-18-f-fdg-pet-ct
#5
Changyun Xu, Chao Ma, Yongli Bai
We present a case of a 13 years old boy who was hospitalized with a 10 months history of progressive pain and weakness in his lower extremities. The laboratory tests revealed slightly decreased phosphate and 25-hydroxyvitamin D3, high alkaline phosphatase, normal calcium and parathyroid hormone (PTH). Magnetic resonance imaging (MRI) showed multiple patchy lesions indicating bone destruction in the metaphyses and epiphyses of the left knee. Fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography ((18)F-FDG PET/CT) revealed a generalized decrease of bone density in axial bones with slightly increased (18)F-FDG metabolism...
January 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/28315916/muscular-damage-in-a-patient-with-hepatitis-b-induced-by-beta-l-2-deoxythymidine-and-detected-by-18-f-fdg-pet-ct
#6
Jinhua Zi, Changyun Xu, Xuemei Zhang
A 58 years old man under 2'-Deoxy-L-thymidine treatment for his hepatitis B was admitted to our hospital complaining for the last 2 months of recurrent upper abdomen discomfort, fatigue and weight loss of 10 kilograms and general muscular soreness, for 2 weeks. He had elevated creatine kinase (CK), myoglobin, CK-MB and other related or common laboratory findings. Fluorine-18- fluorodeoxyglucose positron emission tomography/ computed tomography ((18)F-FDG PET/CT) showed a diffuse, homogenous, moderately elevated glucose uptake in all muscle groups...
January 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/28315915/four-patients-with-gastrointestinal-bleeding-identified-by-a-modified-in-vivo-technique-with-labeled-red-blood-cells-sedimentation
#7
Kang-Hung Chao, Cheng-Kai Huang, Dmytro Luzhbin, Jay Wu
OBJECTIVE: Gastrointestinal bleeding scintigraphy (GIBS) offers the advantage of continuous monitoring of patients to localize the site of gastrointestinal bleeding. In this study, a modified in vivo labeling method with sedimentation of the labeled red blood cells (RBC) was applied to remove free technetium-99m ((99m)Tc) and increase labeling efficiency. PATIENTS AND METHODS: Four patients were studied. A modified in vivo RBC labeling method was used. After 10 minutes of RBC sedimentation, patients' blood plasma in the upper part of the syringe was removed, and the erythrocytes labeled with (99m)Tc were re-administered to the patient...
January 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/28315914/the-beginning-of-using-x-rays-and-the-evolution-of-equipment-for-the-treatment-of-ocular-cancer
#8
Konstantinos Laios, Maria Zozolou, George Generalis, Maria Lymperi, Chryssanthy Koutsandrea, Marilita M Moschos
Until the early 20(th)century enucleation of the eyeball or its partial excision were the basic treatments for ocular cancer. The discovery of X-rays by Wilhelm Conrad Röntgen (1845-1923) offered new possibilities to the treatment of ocular cancer either as mono or as adjuvant therapy. Nowdays this treatment is more sophisticated.
January 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/28315913/does-dual-time-point-18-f-fdg-pet-ct-scan-add-in-the-diagnosis-of-hepatocellular-carcinoma
#9
Bing Wu, Yanzhao Zhao, Yiqiu Zhang, Hui Tan, Hongcheng Shi
OBJECTIVE: The aim of this study was to evaluate the usefulness of dual-time-point (18)F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) with semiquantitative analyses for patients with hepatocellular carcinoma (HCC). SUBJECTS AND METHODS: The 150 patients with clinically suspected liver malignancies underwent dual-time-point (18)F-FDG PET/CT imaging. The maximum standardized uptake value (SUVmax) was calculated at both time points of PET imaging...
January 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/28315912/an-imaging-target-tgf-%C3%AE-1-for-hepatocellular-carcinoma-in-mice
#10
Yiqiu Zhang, Beilei Li, Xiao Li, Hui Tan, Dengfeng Cheng, Hongcheng Shi
It has been reported that the positive detection rate of Fluorine-18-fluorodeoxyglucose ((18)F-FDG) metabolism in positron emission tomography (PET) imaging, for the diagnosis of hepatocellular carcinoma (HCC) is only about 50%. In particular, (18)F-FDG PET imaging is prone to false negative findings in HCC. Transforming growth factor-beta1 (TGF-β1) shows over expression rates in early HCC liver tissue growth and promotes tumor invasion and metastases. Our aim was to use In this study, we used the feasibility of iodine-125 ((125)I)-labeled TGF-β1 antibody as a nuclear medicine imaging target in HCC...
January 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/28315911/reproducibility-of-a-semi-quantitative-lobar-pulmonary-ventilation-and-perfusion-technique-using-spet-and-ct
#11
Esber N El-Barhoun, Ghee Chew, Benjamin Crouch, Barry Chatterton
OBJECTIVE: Evaluation of regional lung function is valuable prior to lung surgery in patients with chronic lung disease. Our aim was to evaluate the reproducibility of a locally developed single photon emission tomography/computed tomography (SPET/CT) programme between and within three observers in assessing lobar pulmonary volumes, perfusion and ventilation. SUBJECTS AND METHODS: Twelve lung transplantation candidates had VQ SPET and diagnostic CT to determine lobar pulmonary function and plan surgery...
January 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/28315910/effect-of-selenium-supplementation-for-protection-of-salivary-glands-from-iodine-131-radiation-damage-in-patients-with-differentiated-thyroid-cancer
#12
RANDOMIZED CONTROLLED TRIAL
Haiyoung Son, Sang Mi Lee, Ra Gyoung Yoon, Hakmin Lee, Ilkyun Lee, Soon Kim, Woong Youn Chung, Jeong Won Lee
OBJECTIVE: In the current study, we examined whether selenium supplementation during iodine-131 ((131)I) treatment had a radio-protective effect on salivary glands. SUBJECTS AND METHODS: Sixteen patients with differentiated thyroid cancer were prospectively enrolled in the study. Patients after total thyroidectomy, before (131)I treatment, were divided into two groups; 8 patients in the selenium group and 8 patients in the control group. Patients in the selenium group received 300νg of selenium orally for 10 days, from 3 days before to 6 days after (131)I treatment...
January 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/28315909/a-concise-review-of-hashimoto-thyroiditis-ht-and-the-importance-of-iodine-selenium-vitamin-d-and-gluten-on-the-autoimmunity-and-dietary-management-of-ht-patients-points-that-need-more-investigation
#13
REVIEW
Michael I Liontiris, Elias E Mazokopakis
Hashimoto's thyroiditis (HT) is a chronic autoimmune thyroid disease caused by an interaction between genetic factors and environmental conditions, both of which are yet to be fully understood. The management of HT depends on its clinical manifestations, commonly including diffuse or nodular goiter with euthyroidism, subclinical hypothyroidism and permanent hypothyroidism. However, in most cases of patients with HT, lifelong levothyroxine substitution is required. The additional role of diet for the management of HT is usually overlooked...
January 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/28315908/positive-99m-tc-mibi-and-the-subtraction-parathyroid-scan-are-related-to-intact-parathyroid-hormone-but-not-to-total-plasma-calcium-in-primary-hyperparathyroidism
#14
COMPARATIVE STUDY
Sanja Dugonjić, Marija Šišić, Marija Radulović, Boris Ajdinović
OBJECTIVE: Primary hyperparathyroidism (pHPT) is characterised by increased parathyroid hormone (PTH) secretion and consequently increased plasma calcium. During the last few decades parathyroid scintigraphy (PS), is applied in almost all patients with pPHT before surgery and specifically before minimally invasive parathyroidectomy. The aim of this study was to find the best cut-off levels of total plasma calcium and intact PTH (iPTH) that correlate with positive technetium-99m-methoxy isobutyl isonitrile ((99m)Tc-MIBI) PS and with positive subtraction PS (SPS) in patients with pHPT and thus the positive diagnostic value of these PS...
January 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/28315907/can-preoperative-cea-and-ca19-9-serum-concentrations-suggest-metastatic-disease-in-colorectal-cancer-patients
#15
Milica Stojkovic Lalosevic, Sanja Stankovic, Mirjana Stojkovic, Velimir Markovic, Ivan Dimitrijevic, Jovan Lalosevic, Jelena Petrovic, Marija Brankovic, Aleksandra Pavlovic Markovic, Zoran Krivokapic
OBJECTIVE: This study was designed to investigate the efficiency of preoperative serum carcinoembryonic antigen (CEA) and carbohydrate cancer antigen (CA19-9) levels for diagnosing synchronous liver metastases and lymph node in colorectal carcinoma (CRC) patients. SUBJECTS AND METHODS: A total of 300 patients with histologically diagnosed CRC were included in this study between May 2014 and March 2015. The data were obtained prospectively from patient's medical records: medical history, demographics, tumor location, differentiation (grade), depth of the tumor (T), lymph node metastases (N), distant metastases (M), lymphatics, venous and perineural invasion, and disease stage...
January 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/28315906/nineteen-cases-with-synchronous-multiple-primary-cancers-studied-by-18-f-fdg-pet-ct
#16
Lifang Pang, Guobing Liu, Hongcheng Shi, Pengcheng Hu, Beilei Li, Dengfeng Cheng
OBJECTIVE: To evaluate the value of fluorine -18-fuoro-2-deoxyglucose positron emission tomography/computed tomography ((18)F-FDG PET/CT) in evaluating synchronous multiple primary cancers (SMPC). METHODS: Nineteen patients with pathologically-confirmed SMPC were collected. Clinical and (18)F-FDG PET/CT characteristics of these patients were reviewed and analyzed. Maximum standardized uptake value, (SUVmax) of all lesions was measured and difference (Δ)SUVmax between the SUV of two primary tumors in each patient was calculated as: [(the larger SUVmax - the smaller SUVmax)/ the larger SUVmax]×100%...
January 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/28315905/breast-specific-gamma-camera-imaging-with-99m-tc-mibi-has-better-diagnostic-performance-than-magnetic-resonance-imaging-in-breast-cancer-patients-a-meta-analysis
#17
REVIEW
Aimi Zhang, Panli Li, Qiufang Liu, Shaoli Song
OBJECTIVE: This study aimed to evaluate the diagnostic role of breast-specific gamma camera imaging (BSGI) with technetium-99m-methoxy isobutyl isonitrile ((99m)Tc-MIBI) and magnetic resonance imaging (MRI) in patients with breast cancer through a meta-analysis. METHODS: Three reviewers searched articles published in medical journals before June 2016 in MEDLINE, EMBASE and Springer Databases; the references listed in original articles were also retrieved. We used the quality assessment of diagnostic accuracy studies (QUADAS) tool to assess the quality of the included studies...
January 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/28315904/prognostic-value-of-bone-marrow-18-f-fdg-uptake-on-pet-ct-in-lymphoma-patients-with-negative-bone-marrow-involvement
#18
Jeong Won Lee, Sang Cheol Lee, Han Jo Kim, Sang Mi Lee
OBJECTIVE: The study evaluated the significance of 18F fluorodeoxyglucose ((18)F-FDG) uptake of bone marrow (BM) for predicting progression-free survival (PFS) in lymphoma patients without BM involvement. SUBJECTS AND METHODS: Ninety-five patients with histopathologically proven lymphoma, 7 Hodgkin's lymphoma and 88 non-Hodgkin's lymphoma, who underwent (18)F-FDG positron emission tomography/computed tomography (PET/CT) and BM biopsy for staging work-up and 40 normal subjects were retrospectively enrolled...
January 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/28315903/reconsideration-of-the-primary-and-secondary-diagnostic-criteria-of-meckel-s-diverticulum-scintigraphy-a-study-of-93-confirmed-cases
#19
Ha Wu, Xiaofei Zhao, Yiwei Li, Ruifang Zhao
OBJECTIVE: Meckel's diverticulum scintigraphy (MDS) is a common method for diagnosing ectopic gastric mucosa (EGM), but atypical images are difficult to diagnose. This study aimed to improve the understanding of the existing diagnostic criteria through a review of confirmed cases. SUBJECTS AND METHODS: A total of 352 patients underwent MDS. Among 120 patients with a positive diagnosis, 106 underwent surgery. This study analyzed the imaging presentation, surgical records, and pathological results...
January 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/28315902/postoperative-radioactive-iodine-131-ablation-is-not-necessary-among-patients-with-intermediate-risk-differentiated-thyroid-carcinoma-a-population-based-study
#20
Hong Zhang, Yuechang Cai, Li Zheng, Zhanlei Zhang, Ningyi Jiang
OBJECTIVE: To assess the effectiveness of radioactive iodine (RAI) ablation among patients with intermediate-risk differentiated thyroid cancer (DTC) following surgery. SUBJECTS AND METHODS: This population based study obtained information from the Surveillance, Epidemiology, and End Results (SEER) Program Research Data (1973-2013). National Cancer Institute, DCCPS, Surveillance Research Programme, Surveillance Systems Branch, released April 2016, based on the November 2015 submission...
January 2017: Hellenic Journal of Nuclear Medicine
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