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Congenital Heart Disease

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https://www.readbyqxmd.com/read/30101544/incidence-of-aspiration-in-infants-with-single-ventricle-physiology-following-hybrid-procedure
#1
Jennifer P Lundine, Robert Dempster, Kirby Carpenito, Holly Miller-Tate, Wendelin Burdo-Hartman, Elizabeth Halpin, Omar Khalid
BACKGROUND: Swallowing dysfunction is a known complication for infants with complex congenital heart disease (CHD), but few studies have examined swallowing outcomes following the hybrid procedure for stage 1 palliation in children with single ventricle physiology. OBJECTIVES: (1) Identify the incidence of aspiration in all infants with single ventricle physiology who underwent the hybrid procedure and (2) Compare results of clinical bedside and instrumental swallowing evaluations to examine the predictive value of a less invasive swallowing assessment for this population of high-risk infants...
August 12, 2018: Congenital Heart Disease
https://www.readbyqxmd.com/read/30101472/fibrosure-and-elastography-poorly-predict-the-severity-of-liver-fibrosis-in-fontan-associated-liver-disease
#2
Jessica L Schachter, Manisha Patel, Samuel R Horton, A Mike Devane, Alex Ewing, Gary A Abrams
OBJECTIVE: As the population of patients with Fontan circulation surviving into adulthood increases, hepatic cirrhosis has grown to be a significant cause of morbidity and mortality. Early detection of advanced hepatic fibrosis is imperative for proper intervention and consideration for heart or combined heart/liver transplantation. Noninvasive biomarkers and elastography have been evaluated for their diagnostic utility with variable results in the Fontan population. DESIGN: The cohort included 14 patients age 26...
August 12, 2018: Congenital Heart Disease
https://www.readbyqxmd.com/read/30095227/is-pulse-oximetry-helpful-for-the-early-detection-of-critical-congenital-heart-disease-at-high-altitude
#3
Fabricio González-Andrade, Daniel Echeverría, Valeria López, Michaela Arellano
OBJECTIVE: To assess the pulse oximetry as a method for screening critical congenital heart disease (CHD) in newborns. STUDY DESIGN: This is an observational, transversal, descriptive simple study. The pre-ductal and postductal saturation were taken in term newborns that fulfilled the criteria of inclusion and exclusion in the Hospital Gineco-Obstetrico Isidro Ayora (HGOIA) in Quito. These measurements were performed between the 24 and 48 h after birth. Those newborns that saturated less than 90% on initial pulse oxìmetry underwent 3 successive measurements at 1-h intervals...
August 10, 2018: Congenital Heart Disease
https://www.readbyqxmd.com/read/30095223/reintervention-following-stage-1-palliation-a-report-from-the-npc-qic-registry
#4
Matthew W Buelow, Nancy Rudd, Jena Tanem, Pippa Simpson, Peter Bartz, Garick Hill
BACKGROUND: Single ventricle heart disease with aortic arch hypoplasia has high morbidity and mortality, with the greatest risk after stage 1 palliation. Residual lesions often require catheter-based or surgical reintervention to minimize risk. We sought to describe the types, frequency, and risk factors for re-intervention between stage 1 and stage 2 palliation, utilizing the National Pediatric Cardiology Quality Improvement Collaborative (NPC-QIC) registry. METHODS: The NPC-QIC registry, consisting of patients discharged after stage 1 palliation, was queried...
August 10, 2018: Congenital Heart Disease
https://www.readbyqxmd.com/read/30079627/renal-dysfunction-is-associated-with-higher-central-venous-pressures-in-patients-with-fontan-circulation
#5
Christopher R Broda, Hamsini Sriraman, Devanshi Wadhwa, Yunfei Wang, Hari Tunuguntla, Ayse Akcan-Arikan, Peter R Ermis, Jack F Price
PURPOSE: Elevated central venous pressure (CVP) has deleterious effects on several organ systems in patients with Fontan circulation. However, the relationship between CVP and estimated glomerular filtration rate (eGFR) has not been assessed in patients with Fontan circulation. METHODS: Patients with Fontan circulation whose hemodynamics were assessed by catheterization between 1987 and 2015 and had a serum creatinine measured within 72 hours prior to the procedure were included for analysis...
August 5, 2018: Congenital Heart Disease
https://www.readbyqxmd.com/read/30066452/identifying-self-reported-neurocognitive-deficits-in-the-adult-with-congenital-heart-disease-using-a-simple-screening-tool
#6
Ashley Brunmeier, Michael P Reis, Michael G Earing, Laura Umfleet, Salil Ginde, Peter J Bartz, Scott Cohen
OBJECTIVE: Children with congenital heart disease (CHD) and adults with acquired heart disease are at an increased risk of neurocognitive impairment. The objective of this study was to determine the prevalence of self-reported neurocognitive impairment and its risk factors in the adult congenital heart disease (ACHD) population. DESIGN: The Wisconsin Adult Congenital Heart Disease Program recently began screening ACHD patients to identify those with significant self-perceived neurocognitive impairments...
July 31, 2018: Congenital Heart Disease
https://www.readbyqxmd.com/read/30066365/risk-factors-for-hyperuricemia-in-congenital-heart-disease-patients-and-its-relation-to-cardiovascular-death
#7
Juan Lizandro Rodríguez-Hernández, Fayna Rodríguez-González, Marta Riaño-Ruiz, Efrén Martínez-Quintana
INTRODUCTION: Hyperuricemia has been associated with cardiovascular risk factors but it remains controversial if uric acid is an independent predictor of cardiac mortality. METHODS: A total of 503 CHD patients (457 nonhypoxemic and 46 hypoxemic) and 772 control patients fulfilled inclusion criteria. Demographic, clinical, and analytical data [serum uric acid and 24h urine uric acid levels, N-terminal pro-B-type natriuretic peptide (NT-pro-BNP), and C-reactive-protein (CRP) concentrations] were studied...
July 31, 2018: Congenital Heart Disease
https://www.readbyqxmd.com/read/30047244/narrative-analysis-of-adults-with-complex-congenital-heart-disease-childhood-experiences-and-their-lifelong-reverberations
#8
Michelle Keir, Barbara Bailey, Angela Lee, Adrienne H Kovacs, S Lucy Roche
BACKGROUND: With access to surgical care, >90% of today's infants with congenital heart disease (CHD) will reach adulthood. During childhood, survivors accrue a wealth of health care experience and develop strategies for navigating life with a chronic disease. METHODS: Seeking to learn from this individualized process, we invited adults with complex CHD to participate in narrative analysis-an established qualitative research method for studying how individuals derive meaning from their personal stories...
July 26, 2018: Congenital Heart Disease
https://www.readbyqxmd.com/read/30039518/heart-murmurs-and-echocardiography-findings-in-the-normal-newborn-nursery
#9
Michael E Fenster, John S Hokanson
OBJECTIVE: To determine the clinical findings and management implications of echocardiograms performed on infants with murmurs in the nursery. DESIGN: Retrospective cohort study conducted from January 2008 through December 2015. Patients in the study were followed by chart review for up to 5 years. In addition, a survey of nursery providers was conducted in February 2016. SETTING: A single community hospital associated with a university. PATIENTS: All 26 573 infants who received care in the normal newborn nursery were eligible for inclusion in the study...
July 24, 2018: Congenital Heart Disease
https://www.readbyqxmd.com/read/30033686/anticoagulation-practices-in-adults-with-congenital-heart-disease-and-atrial-arrhythmias-in-switzerland
#10
Ketina Arslani, Lukas Notz, Marzena Zurek, Matthias Greutmann, Markus Schwerzmann, Judith Bouchardy, Reto Engel, Christine Attenhofer Jost, Daniel Tobler
BACKGROUND: In adults with congenital heart disease (CHD) and atrial arrhythmias, recommendations for thromboprophylaxis are vague and evidence is lacking. We aimed to identify factors that influence decision-making in daily practice. METHODS: From the Swiss Adult Congenital HEart disease Registry (SACHER) we identified 241 patients with either atrial fibrillation (Afib) or atrial flutter/intraatrial reentrant tachycardia (Aflut/IART). The mode of anticoagulation was reviewed...
July 22, 2018: Congenital Heart Disease
https://www.readbyqxmd.com/read/30033682/outcomes-in-patients-with-cor-triatriatum-sinister
#11
Margaret M Fuchs, Heidi M Connolly, Sameh M Said, Alexander C Egbe
OBJECTIVE: To describe outcomes in patients with cor triatriatum sinister (CTS). DESIGN: Retrospective review of patients with CTS followed at Mayo Clinic Rochester from 1990 to 2016. Clinical notes, operative reports, and baseline imaging studies were reviewed including echocardiogram, magnetic resonance imaging, computed tomography, and cardiac catheterization. RESULTS: Fifty-seven patients (median age 34 years; men 32 (56%)) were enrolled...
July 22, 2018: Congenital Heart Disease
https://www.readbyqxmd.com/read/30033669/right-aortic-arch-with-situs-solitus
#12
William N Evans, Ruben J Acherman, Dean Berthoty, Gary A Mayman, Michael L Ciccolo, Sergio A Carrillo, Humberto Restrepo
PATIENTS: We reviewed all patients evaluated at our center with situs solitus, levocardia, and a right aortic arch that were born between January 2000 and January 2018. RESULTS: From our databases, we identified 204 patients. We excluded patients with a double aortic arch from analysis. Of the 204 patients, 103 (50%) were male. Of the 204 patients, 95 (47%) had an isolated right aortic arch. Of the 95 with an isolated right aortic arch, 4 (4%) had chromosome 22q11...
July 22, 2018: Congenital Heart Disease
https://www.readbyqxmd.com/read/30033665/incidence-and-factors-influencing-the-spontaneous-closure-of-fontan-fenestration
#13
Sudheer R Gorla, Nataley K Jhingoeri, Abhishek Chakraborty, Kishore R Raja, Ashish Garg, Satinder Sandhu, Eliot R Rosenkranz, Sethuraman Swaminathan
INTRODUCTION: The Fontan operation is the final stage of single ventricle palliation in patients with complex congenital heart disease. Fenestration in the Fontan conduit, providing an atrial level right to left shunt, has been shown to reduce early postoperative morbidity. However, there is limited data on the long-term fate of this fenestration. The aim of this study is to define the rate of spontaneous closure of the fenestration in the Fontan conduit and factors predictive of the fate of the fenestration...
July 22, 2018: Congenital Heart Disease
https://www.readbyqxmd.com/read/30033580/a-qualitative-assessment-of-pediatric-cardiology-core-content-comments-from-kentucky-trainees-pediatricians-and-pediatric-cardiologists
#14
Ashley E Neal, Elizabeth Lehto, Karen Hughes Miller, Erin Davis, Craig Ziegler
OBJECTIVE: The 2016 American Board of Pediatrics (ABP) content outline is comprehensive, including more than 50 cardiology-specific objectives within eight content areas. This study complements the quantitative analysis of a Kentucky-wide survey of trainees, pediatricians, and pediatric cardiologists asking them to identify "most important" cardiology content by analyzing their open-ended comments about "what should be added" and "why?" within these eight categories...
July 22, 2018: Congenital Heart Disease
https://www.readbyqxmd.com/read/30033572/pheochromocytoma-and-paraganglioma-in-fontan-patients-common-more-than-expected
#15
Mi Kyoung Song, Gi Beom Kim, Eun Jung Bae, Young Ah Lee, Hyun-Young Kim, Seung-Kee Min, Jung Hee Kim, Jae-Kyung Won
OBJECTIVE: Pheochromocytoma and paraganglioma (extra-adrenal pheochromocytoma) are rare neuroendocrine tumors that arise from the neuroendocrine cells. Chronic hypoxia is known as a possible cause, and a strong link between cyanotic congenital heart disease and these tumors has been reported. However, reports of phechromocytoma/paraganglioma in Fontan patients were scarce. We herein report seven cases of phechromocytoma/paraganglioma after Fontan operation at a single tertiary center...
July 22, 2018: Congenital Heart Disease
https://www.readbyqxmd.com/read/30033554/functional-limitations-and-educational-needs-among-children-and-adolescents-with-heart-disease
#16
Sherry L Farr, Karrie F Downing, Tiffany Riehle-Colarusso, Ginnie Abarbanell
OBJECTIVE: To examine how cognitive and motor limitations in children with heart disease are associated with education and participation in extracurricular activities. DESIGN: Using 2009-2010 parent-reported data from the National Survey of Children with Special Health Care Needs (NS-CSHCN), we examined prevalence of five functional limitations (learning/concentration, communication, self-care, gross motor skills, and fine motor skills) by diagnosed heart disease status using chi-square tests and multivariable logistic regression...
July 22, 2018: Congenital Heart Disease
https://www.readbyqxmd.com/read/30022622/interstage-outcomes-in-single-ventricle-patients-undergoing-hybrid-stage-1-palliation
#17
Janet M Simsic, Christina Phelps, Kristin Kirchner, Kirby-Rose Carpenito, Robin Allen, Holly Miller-Tate, Karen Texter, Mark Galantowicz
OBJECTIVE: Interstage readmissions are common in infants with single ventricle congenital heart disease undergoing staged surgical palliation. We retrospectively examined readmissions during the interstage period. DESIGN: Retrospective analysis. SETTING: The Heart Center at Nationwide Children's Hospital, Columbus, Ohio. PATIENTS: Newborns undergoing hybrid stage 1 palliation from January 2012 to December 2016 who survived to hospital discharge and were followed at our institution...
July 18, 2018: Congenital Heart Disease
https://www.readbyqxmd.com/read/30022603/prenatal-detection-of-critical-cardiac-outflow-tract-anomalies-remains-suboptimal-despite-revised-obstetrical-imaging-guidelines
#18
Heather Y Sun, James A Proudfoot, Rachel T McCandless
BACKGROUND: Fetal echocardiography can accurately diagnose critical congenital heart disease prenatally, but relies on referrals from abnormalities identified on routine obstetrical ultrasounds. Critical congenital heart disease that is frequently missed due to inadequate outflow tract imaging includes anomalies such as truncus arteriosus, double outlet right ventricle, transposition of the great arteries, tetralogy of Fallot, pulmonary stenosis, and aortic stenosis. OBJECTIVE: This study evaluated the prenatal detection rate of critical outflow tract anomalies in a single urban pediatric hospital before and after "AIUM Practice Guideline for the Performance of Obstetric Ultrasound Examinations," which incorporated outflow tract imaging...
July 18, 2018: Congenital Heart Disease
https://www.readbyqxmd.com/read/30019505/what-is-the-role-of-apical-ventriculotomy-in-children-and-young-adults-with-hypertrophic-cardiomyopathy
#19
Alex J Thompson, Joseph A Dearani, Jonathan N Johnson, Hartzell V Schaff, Eric C Towe, Jared Palfreeman, Philip L Wackel, Frank Cetta
BACKGROUND: The transapical approach has been utilized in adult HCM patients with either midventricular obstruction or a small LV cavity; however, there are little data on its use in children. METHODS: We retrospectively reviewed all patients (age <21 years) with HCM who underwent a transapical myectomy from January 2002 to December 2016. Indication for surgery was midventricular obstruction in 19/23 (83%) and small LV cavity in 4 (17%). Preoperative symptoms included: dyspnea (96%), chest pain (65%), presyncope (61%), and syncope (35%)...
July 17, 2018: Congenital Heart Disease
https://www.readbyqxmd.com/read/30019493/angiotensin-converting-enzyme-inhibitors-and-interstage-failure-in-infants-with-hypoplastic-left-heart-syndrome
#20
Doris P Yimgang, John D Sorkin, Charles F Evans, Danielle S Abraham, Geoffrey L Rosenthal
INTRODUCTION: Angiotensin converting enzyme inhibitors are commonly prescribed medications after the Norwood procedure. There are little data that can be used to determine if angiotensin converting enzyme inhibitors improve interstage outcomes in children with single ventricle defects. The objective of this study was to investigate the relationship between angiotensin converting enzyme inhibitors and interstage failure among infants born with hypoplastic left heart syndrome. METHODS: We conducted a retrospective cohort study using data from the National Pediatric Cardiology Quality Improvement Collaborative database (collected between 2008 and 2015)...
July 17, 2018: Congenital Heart Disease
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