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Breast Care

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https://www.readbyqxmd.com/read/30069183/parp-inhibitors-in-breast-cancer-why-how-and-when
#1
Angelo Paradiso, Eleni Andreopoulou, Pierfranco Conte, Alexandru Eniu, Mahasti Saghatchian
No abstract text is available yet for this article.
July 2018: Breast Care
https://www.readbyqxmd.com/read/30069182/ago-recommendations-for-the-diagnosis-and-treatment-of-patients-with-advanced-and-metastatic-breast-cancer-update-2018
#2
Marc Thill, Cornelia Liedtke, Volkmar Müller, Wolfgang Janni, Marcus Schmidt
No abstract text is available yet for this article.
July 2018: Breast Care
https://www.readbyqxmd.com/read/30069181/ago-recommendations-for-the-diagnosis-and-treatment-of-patients-with-early-breast-cancer-update-2018
#3
Cornelia Liedtke, Christian Jackisch, Marc Thill, Christoph Thomssen, Volkmar Müller, Wolfgang Janni
No abstract text is available yet for this article.
July 2018: Breast Care
https://www.readbyqxmd.com/read/30069180/a-case-report-of-triple-positive-micropapillary-carcinoma-of-the-male-breast
#4
Jamila Shuja, Iftikhar Ahmad, Sidra Arshad, Hina Manzoor, Shahwali Kakar, Khushnaseeb Ahmad
Background: Micropapillary carcinoma (MPC), a morphologically distinct subtype of invasive ductal carcinoma, of the male breast is an exceedingly uncommon disease. Case Report: Herein, we report a case of triple-positive MPC of the male breast with axillary lymph node involvement and no recurrence for over 2 years. Specifically, a 60-year-old male patient presented with a hard, elastic, and well-defined painless mass in the right breast. The patient underwent unilateral (right) modified radical mastectomy with axillary clearance...
July 2018: Breast Care
https://www.readbyqxmd.com/read/30069179/effects-of-music-intervention-on-the-physical-and-mental-status-of-patients-with-breast-cancer-a-systematic-review-and-meta-analysis
#5
REVIEW
Xia Wang, Yin Zhang, Yao Fan, Xiang-Sheng Tan, Xun Lei
Background: The aim of this review was to evaluate the effects of music intervention on the physical and mental status of patients with breast cancer. Methods: 9 databases were searched; 30 randomized controlled trials that compared the effects of music plus standard care and standard care alone in patients with breast cancer were included. Methodological quality was assessed using the Jadad scale. Results: The results of the meta-analysis suggested that music intervention was significantly effective in lowering systolic blood pressure (standardized mean difference (SMD) -0...
July 2018: Breast Care
https://www.readbyqxmd.com/read/30069178/metronomic-chemotherapy-for-first-line-treatment-of-metastatic-triple-negative-breast-cancer-a-phase-ii-trial
#6
Emilia Montagna, Vincenzo Bagnardi, Giuseppe Cancello, Claudia Sangalli, Eleonora Pagan, Monica Iorfida, Manuelita Mazza, Giovanni Mazzarol, Silvia Dellapasqua, Elisabetta Munzone, Aaron Goldhirsch, Marco Colleoni
Background: Few data are available on the benefit of metronomic cyclophosphamide, capecitabine, and vinorelbine as first-line therapy in patients with metastatic triple-negative breast cancer. Methods: This phase II study assessed the safety and efficacy of metronomic oral chemotherapy with vinorelbine 40 mg orally 3 times a week, cyclophosphamide 50 mg daily, and capecitabine 500 mg 3 times a day (VEX regimen) in untreated metastatic triple-negative breast cancer patients...
July 2018: Breast Care
https://www.readbyqxmd.com/read/30069177/lymph-node-radiotherapy-instead-of-extended-axillary-surgery-the-new-standard
#7
REVIEW
Peter Niehoff, Silla Hey-Koch
Breast cancer treatment has undergone major changes in the last 20 years. Specifically, the role of axillary lymph node dissection has changed from radical axillary dissection with excision of a high number of lymph nodes to sentinel lymph node biopsy (SLNB). This paradigm shift is associated with a controversial debate regarding the significance of axillary staging, the need for surgery, and the role of radiotherapy. Looking ahead, lymph node staging and axillary treatment might shift from SLNB and/or axillary dissection to ultrasound-guided needle biopsy and irradiation of regional lymph nodes in order to reduce treatment-related sequelae in early-stage breast cancer...
July 2018: Breast Care
https://www.readbyqxmd.com/read/30069176/proton-therapy-for-primary-breast-cancer
#8
REVIEW
Eugen B Hug
Proton therapy reduces the integral dose received by normal tissues due to its physical properties of dose deposition in the Bragg peak. In a small but significant percentage of patients requiring adjuvant radiotherapy (RT) for left-sided breast cancer, photon-based RT can lead to cardiac complications during long-term follow-up. The risk of cardiac complications is correlated with the dose to the coronary arteries and to the general 'mean heart dose'. Dosimetric comparison analysis has identified advantages of proton therapy in accomplishing sparing of the heart with increasing target complexity while permitting uncompromised target coverage of the chest wall ± breast plus draining lymphatics...
July 2018: Breast Care
https://www.readbyqxmd.com/read/30069175/intraoperative-electron-radiotherapy-ioert-in-the-treatment-of-primary-breast-cancer
#9
REVIEW
Julia Kaiser, Roland Reitsamer, Peter Kopp, Christoph Gaisberger, Michael Kopp, Thorsten Fischer, Franz Zehentmayr, Felix Sedlmayer, Gerd Fastner
IOERT (intraoperative electron radiotherapy) in breast cancer is used either as a boost (10-12 Gy) followed by whole breast irradiation (WBI) or as full-dose partial breast irradiation (PBI, 20-24 Gy) during breast-conserving surgery. IOERT has the longest evidence of all IORT techniques. When administered as a boost, excellent low local recurrence rates were observed in long-term follow-up >5 years. Even in high-risk groups like triple-negative or locally advanced breast cancers, IOERT contributes to long-term local control rates of more than 90%...
July 2018: Breast Care
https://www.readbyqxmd.com/read/30069174/the-role-of-brachytherapy-in-the-treatment-of-breast-cancer
#10
REVIEW
Daniela Kauer-Dorner, Daniel Berger
Radiotherapy plays an important part in the management of breast cancer. Especially after breast-conserving surgery, external whole breast irradiation, occasionally with an additional local boost, is an integral part of breast conservation. Besides external radiation techniques, brachytherapy (BT) has long been among the treatment options, especially with regard to local boost application. With the emerging implementation of accelerated partial breast irradiation (APBI), BT in general and interstitial multi-catheter BT in particular, are gaining an increasing role in the management of a selected group of early breast cancer patients...
July 2018: Breast Care
https://www.readbyqxmd.com/read/30069173/advances-in-breast-radiotherapy-brachytherapy-intraoperative-electron-therapy-protons-and-nodal-irradiation
#11
EDITORIAL
Joachim Widder
No abstract text is available yet for this article.
July 2018: Breast Care
https://www.readbyqxmd.com/read/29887793/molecular-tumor-boards
#12
Achim Rody, Johannes Ettl, Frederik Marmé, Aleix Prat
No abstract text is available yet for this article.
April 2018: Breast Care
https://www.readbyqxmd.com/read/29887792/a-clinical-observation-of-thymic-epithelial-tumor-metastatic-to-breast
#13
Yu-Wei Deng, Yi-Wen Li, Wen-Jing Hao, Dan Lu
Background: Thymic carcinoma is prone to early metastasis and invasion, while its metastasis to the breast is particularly unique. Case Report: We describe a case of thymic epithelial tumor metastatic to the breast fulfilling clinical diagnostic criteria. A 47-year-old female patient diagnosed with stage IV thymic carcinoma and previously treated with chemoradiation was diagnosed with metastatic breast cancer during a periodic review. Color Doppler ultrasonography showed a low-echo real occupancy in the breast...
April 2018: Breast Care
https://www.readbyqxmd.com/read/29887791/axillary-web-syndrome-in-breast-cancer-a-prevalent-but-under-recognized-postoperative-complication
#14
REVIEW
Susan R Harris
The purpose of this review is to define axillary web syndrome (AWS) and describe its diagnosis and management. The following databases were searched through July 2017: PubMed, EMBASE (OvidSP), Cumulative Index for Nursing and Allied Health Literature, Physiotherapy Evidence Database, and Cochrane Database of Systematic Reviews. Search terms included 'axillary web syndrome', 'axillary cording', and 'lymphatic cording'. 49 articles were identified; 8 did not relate to breast cancer, and 3 were not in English...
April 2018: Breast Care
https://www.readbyqxmd.com/read/29887790/evaluation-of-reproductive-concerns-and-biographical-impact-of-breast-cancer-in-young-patients
#15
Maximiliane Burgmann, Kerstin Hermelink, Alex Farr, Friederike van Meegen, Annika Heiduschk, Jutta Engel, Thomas Kolben, Tom Degenhardt, Nina Ditsch, Sven Mahner, Nadia Harbeck, Rachel Würstlein
Background: This study evaluates interventions offered to young breast cancer (BC) patients, including fertility preservation, genetic testing, and counseling for parenthood concerns, and analyzes the effect of BC on biographical issues. Methods: Women who were diagnosed with BC at the age of 18-40 years and who underwent treatment at the Breast Center, Ludwig-Maximilian University (LMU) in Munich between 2006 and 2013, were eligible for this study. Patients received a self-developed questionnaire which covered the following topics: fertility preservation, family planning, genetic testing, parenthood concerns and children's needs, partnership status, and employment situation...
April 2018: Breast Care
https://www.readbyqxmd.com/read/29887789/toxicities-associated-with-docetaxel-based-regimens-in-the-adjuvant-treatment-of-early-stage-breast-cancer-a-multicenter-prospective-real-life-experience
#16
Elie El Rassy, Marwan Ghosn, Fadi Farhat, Ziad Bakouny, Tarek Assi, Georges Chahine, Fadi Nasr, Fady Ghassan Haddad, Fadi El Karak, Joseph Kattan
Background: The present study reports on the efficacy and safety of adjuvant docetaxel in real-life patients with early-stage breast cancer. Methods: This is a prospective, multicenter, post-marketing study that evaluates the efficacy and safety of docetaxel-based regimens in patients with early breast cancer treated between 2007 and 2012. Results: A total of 698 female breast cancer patients receiving adjuvant docetaxel-based regimens were included in this study...
April 2018: Breast Care
https://www.readbyqxmd.com/read/29887788/using-a-new-marker-clip-system-in-breast-cancer-tumark-vision%C3%A2-clip-feasibility-testing-in-everyday-clinical-practice
#17
Anna Marlene Rüland, Friederike Hagemann, Mattea Reinisch, Johannes Holtschmidt, Aylin Kümmel, Christine Dittmer-Grabowski, Frank Stöblen, Horst Rotthaus, Volker Dreesmann, Jens-Uwe Blohmer, Sherko Kümmel
Background: This study presents first feasibility experiences with a new 3-dimensional (3D) marker clip system in clinical practice. The rate of clinical complete responses in the treatment of breast cancer patients is increasing; additionally, a change to targeted axillary dissection is being considered after neoadjuvant chemotherapy (NACT). Consequently, marker clips are needed which are reliable and easy to handle even in the axillary lymph node system. Methods: A total of 50 patients from the Breast Care Unit of the Kliniken Essen Mitte were included...
April 2018: Breast Care
https://www.readbyqxmd.com/read/29887787/modifiable-lifestyle-factors-opportunities-for-hereditary-breast-cancer-prevention-a-narrative-review
#18
REVIEW
Jacqueline Lammert, Sabine Grill, Marion Kiechle
Increasing rates of obesity, lack of physical activity, sedentary behavior, and frequent alcohol consumption are major lifestyle-related risk factors for breast cancer. In fact, it has been estimated that about one-third of breast cancer cases are attributable to factors women can change. Most research has focused on examining the impact of one single exposure on breast cancer risk while adjusting for other risk modifiers. Capitalizing on big data, major efforts have been made to evaluate the combined impact of well-established lifestyle factors on overall breast cancer risk...
April 2018: Breast Care
https://www.readbyqxmd.com/read/29887786/mindfulness-in-follow-up-care-after-breast-cancer-can-it-prevent-recurrence
#19
REVIEW
Carola Modica, Klaus Hoenig
This review focuses on the question whether mindfulness in follow-up care can contribute to the prevention of breast cancer (BC) recurrence. We first introduce behavioral risk and protective factors in follow-up care by presenting current research outcomes modulating individual risk for recurrence. We argue that although increased self-awareness is undoubtedly beneficial for BC survivors, it may also trigger adverse effects in vulnerable individuals such as overarousal and impaired emotional regulation. Indeed, research shows that many BC survivors are often confronted with clinical levels of fear of recurrence and anxiety and depressive symptoms...
April 2018: Breast Care
https://www.readbyqxmd.com/read/29887785/physical-activity-exercise-and-breast-cancer-what-is-the-evidence-for-rehabilitation-aftercare-and-survival-a-review
#20
REVIEW
Petra Wirtz, Freerk T Baumann
The current scientific field of exercise interventions in breast cancer is very large. Rehabilitation focuses on restoring or improving quality of life and thus on independence and participation in life. Hence, it is important to investigate exercise interventions in the setting of rehabilitation and aftercare. It is also necessary to determine the influence of physical activity or exercise therapy on the prevention of recurrence and mortality as well as on certain side effects of the disease and its medical treatment in rehabilitation...
April 2018: Breast Care
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