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Current Diabetes Reviews

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https://www.readbyqxmd.com/read/29446746/mechanisms-involved-in-glycemic-control-promoted-by-exercise-in-diabetics
#1
Eric Francelino Andrade, Viviam de Oliveira Silva, Debora Ribeiro Orlando, Luciano Jose Pereira
Diabetes mellitus is a metabolic disease characterized by high glycemic levels for long periods. This disease has a high prevalence in the world population, being currently observed an increase in its incidence. This fact is mainly due to the sedentary lifestyle and hypercaloric diets. Non-pharmacological interventions for glycemic control include exercise, which promotes changes in skeletal muscle and adipocytes. Thus, increased glucose uptake by skeletal muscle and decreased insulin resistance through modulating adipocytes are the main factors that improve glycemic control against diabetes...
February 14, 2018: Current Diabetes Reviews
https://www.readbyqxmd.com/read/29366422/prevalence-of-chronic-diabetic-complications-in-newly-diagnosed-versus-known-type-2-diabetic-subjects-in-a-sample-of-alexandria-population-egypt
#2
Samir Assaad Khalil, Magdy Helmy Megallaa, Kamel Hemida Rohoma, Myriam AbouSeif Guindy, Adel Zaki, Mohamed Hassanein, Amin Helmy Malaty, Hanaa Mohamed Ismael, Ibrahim Fahmy Kharboush, Dalal Nasr-Eldein El Kafash, Hassan Nooman Sallam, Iman Abdelkareem Desouky
BACKGROUND: In Egypt, data on the prevalence of chronic diabetic complications, which are essential for the adjustment of policies and practices related to diabetes care, are scarce. Therefore, the aim of this study was to determine the frequency of chronic complications of diabetes; namely neuropathy, diabetic kidney disease (DKD), retinopathy and peripheral arterial disease (PAD) in newly-diagnosed versus known type 2 diabetic patients. SUBJECTS & METHODS: This is a cross-sectional study that is based on a previous household survey conducted on a representative sample of the population of Alexandria, Egypt...
January 24, 2018: Current Diabetes Reviews
https://www.readbyqxmd.com/read/29359675/consistency-of-toe-systolic-pressures-brachial-systolic-pressures-and-toe-brachial-indices-in-people-with-and-without-diabetes
#3
Robert Trevethan
BACKGROUND & AIMS: Toe systolic blood pressures (TSPs) and toe-brachial indices (TBIs) have been identified as useful adjuncts in the identification of pedal ischemia, peripheral artery occlusive diseases, and risk for either nonhealing of lower extremity wounds or for amputation. Valid measurement of TSPs and TBIs is therefore essential. However, it could be jeopardized by rater, instrument, and intratestee inconsistency. These three sources of inconsistency were examined in this research...
January 22, 2018: Current Diabetes Reviews
https://www.readbyqxmd.com/read/29357808/the-role-of-oestrogen-receptor-beta-er%C3%AE-in-the-aetiology-and-treatment-of-type-2-diabetes-mellitus
#4
Wendy Amy Ofosu, Daahir Mohamed, Olivia Corcoran, Opeolu Oyejide Ojo
INTRODUCTION: Challenges facing the treatment of type 2 diabetes necessitate the search for agents which act via alternative pathways to provide better therapeutic outcomes. Recently, an increasing body of evidence implicates the activation of oestrogen receptors (ERα and ERβ) in the development and treatment of underlying conditions in type 2 diabetes. This article summarizes available evidence for the involvement of oestrogen receptors in insulin secretion, insulin resistance as well as glucose uptake and highlights the potential of ERβ as a therapeutic target...
January 19, 2018: Current Diabetes Reviews
https://www.readbyqxmd.com/read/29357807/hyperglycemia-in-hospitalized-diabetic-non-critically-ill-patients-prevalence-correlates-management-and-nurses-attitudes
#5
Ghada El Khoury, Hanine Mansour, Wissam Kabbara, Nibal Chamoun, Nadim Attalah, Pascale Salameh
BACKGROUND: Diabetes Mellitus is a chronic metabolic disease that affects 387 million people around the world. Episodes of hyperglycemia in hospitalized diabetic patients are associated with poor clinical outcomes and increased morbidity and mortality. Therefore, prevention of hyperglycemia is critical to, decrease length of hospital stay and to reduce complications and readmissions. OBJECTIVE: The study aims to examine the prevalence of hyperglycemia and assess the correlates and management of hyperglycemia in diabetic non-critically ill patients...
January 19, 2018: Current Diabetes Reviews
https://www.readbyqxmd.com/read/29357806/correlation-between-white-blood-cell-count-and-insulin-resistance-in-type-2-diabetes-running-title-wbc-and-insulin-resistance
#6
Armin Mahdiani, Masoume Kheirandish, Shokoufeh Bonakdaran
BACKGROUND: The role of chronic inflammation in insulin resistance states and the pathogenesis of metabolic syndrome, cardiovascular disease and diabetes have been reported earlier. White blood cell (WBC) count is an easy marker for estimation of systemic inflammation. OBJECTIVE: This study is to clarify whether WBC count associate with insulin resistance in type 2 diabetic patients. METHOD: This cross sectional study was conducted in 283 patients with type 2 diabetes and in 283 healthy non diabetic subjects as control group...
January 19, 2018: Current Diabetes Reviews
https://www.readbyqxmd.com/read/29332589/validation-of-an-arabic-version-of-the-obesity-related-wellbeing-orwell-97-questionnaire-in-adults-with-obesity
#7
Leila Itani, Simona Calugi, Dima Kreidieh, Germine El Kassas, Dana El Masri, Hana Tannir, Riccardo Dalle Grave, Aya Harfoush, Marwan El Ghoch
BACKGROUND: No specific questionnaire that evaluates Health-Related Quality Of Life (HRQOL) in individuals with obesity is available in the Arabic language. The aim of this study was therefore to propose and examine the validity and reliability of an Arabic language version of the ORWELL 97, a validated obesity-related HRQOL questionnaire. METHODS: The ORWELL 97 questionnaire was translated from English to Arabic language and administered to 318 Arabic-speaking participants (106 from clinical and 212 from community samples), and underwent internal consistency, test-retest reliability, construct and discriminative validity analysis...
January 10, 2018: Current Diabetes Reviews
https://www.readbyqxmd.com/read/29283073/patients-illness-perceptions-of-type-2-diabetes-a-scoping-review
#8
Elena D Dimova, Ashleigh Ward, Vivien Swanson, Josie Mm Evans
BACKGROUND: People's personal perceptions, or illness representations, of type 2 diabetes can act as barriers to successful self-management. INTRODUCTION: Understanding patients' subjective perceptions of type 2 diabetes can aid the design of evidence-based care and appropriate educational programmes. This scoping review provides a narrative account of previous knowledge of patients' illness representations of type 2 diabetes. METHOD: Quantitative and qualitative studies that explored patients' illness representations of type 2 diabetes, as defined by Leventhal's Common Sense Model, were included...
December 27, 2017: Current Diabetes Reviews
https://www.readbyqxmd.com/read/29243583/the-gstm1-and-gstt1-null-genotypes-increase-the-risk-for-type-2-diabetes-mellitus-and-the-subsequent-development-of-diabetic-complications-a-meta-analysis
#9
Sayantan Nath, Sambuddha Das, Aditi Bhowmik, Sankar Kumar Ghosh, Yashmin Choudhury
BACKGROUND: Studies pertaining to association of GSTM1 and GSTT1 null genotypes with risk of T2DM and its complications were often inconclusive, thus spurring the present study. METHODS: Meta-analysis of 25 studies for evaluating the role of GSTM1/GSTT1 null polymorphisms in determining the risk for T2DM and 17 studies for evaluating the role of GSTM1/GSTT1 null polymorphisms in development of T2DM related complications were conducted. RESULTS: Our study revealed an association between GSTM1 and GSTT1 null polymorphism with T2DM (GSTM1; OR=1...
December 15, 2017: Current Diabetes Reviews
https://www.readbyqxmd.com/read/29243582/consensus-validation-of-simpler%C3%A2-a-tool-to-improve-pharmacist-delivery-of-quality-evidence-based-diabetes-care
#10
Shamala Ayadurai, V Bruce Sunderland, Lisa Bg Tee, H Laetitia Hattingh
BACKGROUND: Studies on a structured method used by pharmacists to provide comprehensive, evidence-based diabetes care are lacking. The aim of this study was to prioritise, rank and construct validate indicators categorised as seven treatment factors utilised in the management of diabetes namely: cholesterol, blood pressure and glycaemia control; medication and lifestyle management; cardiovascular risk strategies and education using the Delphi process. METHODS: A Delphi questionnaire consisted of 29 Part 1 and nine Part 2 indicators which were incorporated into a tool called Simpler™...
December 14, 2017: Current Diabetes Reviews
https://www.readbyqxmd.com/read/29284395/editorial-current-challenges-in-islet-transplantation-and-stem-cell-therapies-in-diabetes
#11
EDITORIAL
Miriam Ramirez-Dominguez
No abstract text is available yet for this article.
2018: Current Diabetes Reviews
https://www.readbyqxmd.com/read/29284394/preface
#12
Norman E Cameron
No abstract text is available yet for this article.
2018: Current Diabetes Reviews
https://www.readbyqxmd.com/read/27306960/consequences-of-type-1-and-2-diabetes-mellitus-on-the-cardiovascular-regulation-during-exercise-a-brief-review
#13
Silvana Roberto, Antonio Crisafulli
INTRODUCTION: One challenging problem in patients suffering from Diabetes Mellitus (DM) is the elevate incidence of cardiovascular events. Exercise has been proved useful in reducing cardiovascular risks in these patients. However, both type 1 and 2 DM significantly affect the cardiovascular response during exercise. Therefore, on one side exercise is considered to be a valid therapeutic tool for DM, whereas on the other side during exercise these patients may experience troubles in the cardiovascular regulation...
October 11, 2017: Current Diabetes Reviews
https://www.readbyqxmd.com/read/28982339/healthcare-expenditures-related-to-bmi-and-physical-activity-among-diabetic-older-people-cross-sectio-nal-analysis-of-sabe-study
#14
Denise Rodrigues Bueno, Maria de Fátima Nunes Marucci, Manuela de Almeida Roediger, Yeda Aparecida de Oliveira Duarte
BACKGROUND: The age is a variable positively related to healthcare expenditures Diabetes (DM), however other factors could also be associated. Physical activity, normal weight and engagement on walking would be inversely associated to healthcare expenditures related to DM control. The aim of this study was to describe healthcare diabetic-related expenditures and analyze the associations with body mass index (BMI), physical activity level (PAL), and engagement in walking among Brazilians older people...
October 4, 2017: Current Diabetes Reviews
https://www.readbyqxmd.com/read/28969558/neck-circumference-and-its-correlation-to-other-anthropometric-parameters-and-finnish-diabetes-risk-score-findrisc
#15
Alexei Volaco, Clara Martinuze Martins, Jessica Queiroz Soares, Ana Maria Cavalcanti, Simone Tetu Moyses, Roberto Pecoits Filho, Cristina Pellegrino Baena, Dalton Bertolim Precom
BACKGROUND: The neck circumference (NC) is an anthropometric measure to evaluate obesity. The FINDRISC predicts the risk of developing type 2 diabetes mellitus. Our aims were to identify the mean value of NC in individuals with higher (≥15 points) and lower FINDRISC and to establish cutoff values that indicate individuals with higher FINDRISC. METHODS: It is a population-based, cross-sectional study representative of the city of Curitiba, Brazil. We studied individuals (>18 years), without diabetes mellitus, between August 2013 and August 2014...
October 2, 2017: Current Diabetes Reviews
https://www.readbyqxmd.com/read/28933305/epidemiology-of-diabetes-mellitus-in-the-united-arab-emirates
#16
Hira Abdul Razzak, Alya Harbi, Wael Shelpai, Ahmad Qawas
Background/ Objective: Diabetes mellitus is a non-communicable disease which has become a major global public health issue. This systematic review summarized epidemiological studies related to the prevalence, risk factors, complications, incidence, knowledge, attitude and practices of Diabetes Mellitus (DM) among Arab population in the United Arab Emirates (UAE). METHOD: PubMed, Scopus databases, Science direct, Wiley online library, and other local journals were searched to identify relevant literature using appropriate keywords to retrieve studies conducted in the UAE...
September 20, 2017: Current Diabetes Reviews
https://www.readbyqxmd.com/read/28914196/ethnic-disparity-and-increased-prevalence-of-type-2-diabetes-among-south-asians-aetiology-and-future-implications-for-diabetes-prevention-and-management
#17
Venugopal Vijayakumar, Ramesh Mavathur, Manjunath Nk Sharma
BACKGROUND: Type 2 diabetes mellitus (T2DM) is turning out to be a global health crisis. Current available literature clearly indicates an increased risk of type 2 diabetes amongst South Asian population. OBJECTIVE: The objective of this narrative review is to explore the non-modifiable and modifiable risk factors of T2DM in South Asian population, including their beliefs, attitudes, socio economic and cultural barriers and also to explore the possible implications in designing culture specific diabetes prevention and management programs...
September 15, 2017: Current Diabetes Reviews
https://www.readbyqxmd.com/read/28914195/polymorphism-rs9939609-of-fat-mass-and-obesity-associated-gene-correlation-with-leptin-level-of-obese-women-suffered-from-type-2-diabetes
#18
Mehdi Niknam Moghanloo, Naser Aga Mohammadzadeh, Hajie Lotfi, Rasoul Mahmoudi, Maryam Abbasi, Farzaneh Ghafarian Alipour, Fatemeh Shool, Sadegh Porfar, Nosratollah Zarghami
Background Recent studies reported that Fat Mass and obesity-associated gene (FTO) single nucleotides polymorphisms (SNPs), especially rs9939609, have association with obesity and type 2 diabetes mellitus. On the other hand, many researches confirmed that leptin, an adipocytokine, is related to the obesity and body mass index (BMI) in patients who suffered from type 2 diabetes(T2DM). Objective In this study, the correlation of FTO rs9939609 polymorphism and leptin level was investigated in the obese women who suffered from T2DM...
September 15, 2017: Current Diabetes Reviews
https://www.readbyqxmd.com/read/28914194/diabetic-retinopathy-recent-updates-on-different-biomarkers-and-some-therapeutic-agents
#19
Amjad Ali Khan, Arshad Husain Rahmani, Yousef Homood Aldebasi
BACKGROUND: Diabetic Retinopathy is a leading cause of sight-threatening complication, which occurs due to a number of physiological and metabolic abnormalities during later stages of diabetes. Many of these abnormal changes are consistent with altered oxidative stress, inflammation, genetic set up, advanced glycation end products, and hematological changes. So the altered levels of different biomolecules related to these changes serve as important biomarkers to assess better evaluation and early treatment of this disease...
September 15, 2017: Current Diabetes Reviews
https://www.readbyqxmd.com/read/28875825/study-of-irisin-hormone-level-in-type-2-diabetic-patients-and-patients-with-diabetic-nephropathy
#20
Salah Shelbaya, Manal Mohamed Abushady, Merhan Samy Nasr, Meram Mohamed Bekhet, Yasmine Abd-Al Mageed, Magdy Abbas
BACKGROUND: Type 2 diabetic patients with diabetic nephropathy are associated with multifactorial abnormal energy metabolism. Irisin has been recently introduced as a hormone that is exercise induced and is secreted by skeletal muscles. It is hypothesized that patients with chronic kidney disease usually have abnormal irisin levels. AIM: We aimed to study the level of Irisin hormone in patients with type 2 diabetes and to document if it is related to diabetic nephropathy...
August 29, 2017: Current Diabetes Reviews
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