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Journal of Dietary Supplements

Kusnandar Anggadiredja, Nazhifa Ufamy, Lia Amalia, Neng Fisheri Kurniati, Irianti Bahana Maulida Reyaan
Hyperlipidemia is one of the leading causes of death and requires lipid-lowering treatment to reduce morbidity and mortality. Effective and safe alternative and adjunctive therapies could be beneficial for patients with hyperlipidemia. To assess the effect of a fiber-multivitamin combination product on the lipid parameters low-density lipoprotein cholesterol (LDL-c), high-density lipoprotein cholesterol (HDL-c), total cholesterol (TC), triglyceride (TG), and apolipoprotein B (Apo B) in patients with hypercholesterolemia, we conducted a double-blind, randomized, parallel-group study...
October 31, 2018: Journal of Dietary Supplements
Eunice Mah, Valerie N Kaden, Kathleen M Kelley, DeAnn J Liska
In this double-blind, randomized, placebo-controlled parallel study, we examined the effect of dairy-based beverages (250 mL/day) containing 250 mg of dispersible baker's yeast β-glucan (Wellmune) compared to a macronutrient- and calorie-matched control on upper respiratory tract infection (URTI) in marathon runners. Healthy adults running in the 2017 Austin Marathon consumed either β-glucan (N = 132) or control (N = 225) for the 45 days prior to, day of, and 45 days after the marathon (91 days total)...
October 31, 2018: Journal of Dietary Supplements
Pedro Javier Rodríguez-Hernández, Alejandro Canals-Baeza, Alicia Santamaria-Orleans, Ferran Cachadiña-Domenech
The aim of this study was to assess the impact of omega-3 fatty acid supplementation among other nonpharmacological treatments on mental health and quality of life (QOL) of children with behavioral disorders. An observational multicenter study of 6- to 12-year-old children with behavior-related problems was performed in Spain with a three-month follow-up assessment. The Kidscreen-10 and Strengths and Difficulties Questionnaires (SDQ) were used to assess effectiveness of each intervention. Characteristics of study population were compared with those of the general population...
October 31, 2018: Journal of Dietary Supplements
Carmen Elena Ţebrencu, Tanţa-Verona Iordache, Elena Ionescu, Ruxandra Mihaela Creţu, Ana-Mihaela Florea, Sandu Teodor, Steluta Apostol, Anamaria Zaharia, Anita-Laura Radu, Andrei Sârbu
Separation of naphtodianthrones (NTs) from Hypericum perforatum L. (aerial part of St. John's Wort) is still topical due to some hard-to-beat medicinal attributes of these bioactive compounds. Unfortunately, their low bioavailability (0.06%-0.4%) complicates the extraction process. Therefore, developing straightforward and lower-cost methodologies for NT separation is still a priority. In support of this purpose, for preparing NT formulations from flowers and leaves of wild St. John's Wort (hyperici herba), a cutoff preparative methodology is described herein...
October 31, 2018: Journal of Dietary Supplements
Suganthi Subramani, Haseena Banu Hedyathullah Khan, Shanthi Palanivelu, Sachidanandam Thiruvaiyaru Panchanadham
Semecarpus anacardium is an important herbal drug that has been used against various ailments. To evaluate the cardioprotective effect of the drug against altered cardiac energy metabolism in type-2 diabetes rats, type-2 diabetes was induced in rats by feeding them with a high-fat diet for 2 weeks followed by intraperitoneal injection of streptozotocin (STZ) 35 mg/kg body weight twice 24 h apart and left for 12 weeks to develop cardiovascular complication. The effects of the nut milk extract on the glucose metabolizing enzymes and mitochondrial complex enzymes were studied using biochemical assays...
October 29, 2018: Journal of Dietary Supplements
Hannes Gatterer, Thomas Böcksteiner, Alexander Müller, Helmut Simi, Christoph Krasser, Radosav Djukic, Rainer Schroth, Dietmar Wallner
Intensified training may lead to fatigue or even a state of overreaching with temporary reductions in performance. Any aid helping to prevent these consequences and to better tolerate such a training regime would be of great importance. 5-hydroxymethylfurfural (5-HMF) and α-ketoglutaric acid (α-KG) supplementation has been suggested to support favorable training outcomes but its effectiveness to facilitate adaptations during an intensified training period has never been investigated. During an in-season competition break (2 weeks), seventeen young outfield soccer players (age:14...
October 22, 2018: Journal of Dietary Supplements
John E Lewis, Steven E Atlas, Muhammad H Abbas, Ammar Rasul, Ashar Farooqi, Laura A Lantigua, Frederick Michaud, Sharon Goldberg, Lucas C Lages, Oscar L Higuera, Andrea Fiallo, Eduard Tiozzo, Judi M Woolger, Stephanie Ciraula, Armando Mendez, Allan Rodriguez, Janet Konefal
The primary objective of the study was to evaluate the effects of a hydrolyzed polysaccharide, rice bran arabinoxylan compound (RBAC), on immune, hepatic, and renal function in HIV + individuals. A six-month randomized double-blind placebo-controlled trial was utilized to conduct the intervention. Forty-seven HIV + participants on stable antiretroviral therapy were enrolled and randomly assigned to one of the two study conditions (n = 22 RBAC and n = 25 placebo) and consumed 3 gram/day of either compound for six months...
October 22, 2018: Journal of Dietary Supplements
Suchitra K Panigrahy, Awanish Kumar, Renu Bhatt
Hedychium coronarium Koen., commonly known as ginger lily, is considered an endemic medicinal plant. In the present study, the antidiabetic action of its rhizomes was investigated by α-amylase and α-glucosidase inhibition assay, and the active compounds were identified through bioactivity guided isolation technique. Among the six different extracts, the EA extract has shown highest inhibition, and the subfractions from active EA extract were separated by silica gel column chromatography. The subfraction showing highest inhibition was investigated for its chemical composition by high-resolution liquid chromatography-mass spectroscopy (HRLC-MS/MS)...
October 16, 2018: Journal of Dietary Supplements
Neha Verma, Surbhi Bal, Ranjan Gupta, Neeraj Aggarwal, Anita Yadav
Cadmium (Cd) has a remarkable property of generating oxidative stress. It upregulates the level of reactive oxygen species, which generates damage to lipids, proteins, and DNA The level of oxidative stress by Cd is observed by inhibitory effects of antioxidant enzymes such as catalase, superoxide dismutase, glutathione reductase, and glutathione peroxidase. Piperine is one of the plant-derived alkaloids isolated from Piper nigrum and Piper longum. It diminishes the level of oxidative damage by quenching the free radicals and reactive oxygen species and inhibiting the lipid peroxidation...
October 9, 2018: Journal of Dietary Supplements
Neha Dhyani, Adila Parveen, Aisha Siddiqi, M Ejaz Hussain, Mohammad Fahim
The present study aimed to evaluate the therapeutic and prophylactic potential of Coriandrum sativum extract in isoproterenol-induced heart failure (HF) in Wistar rats. Two weeks after the isoproterenol administration, rats developed severe impairment in left ventricular functions, reduced baroreflex sensitivity, and significant alteration in hemodynamic parameters and lipid profile. HF rats also exhibited enhanced lipid peroxidation and increased expression of endothelin receptors (ETA and ETB ). Therapeutic and prophylactic treatment with C...
October 9, 2018: Journal of Dietary Supplements
Patrick B Wilson
Previous studies indicate that ginger root has pain-relieving properties, but these effects have not been thoroughly examined in the context of distance running. The purpose of this randomized, double-blind, placebo-controlled trial was to determine whether ginger root supplementation reduces muscle soreness and dysfunction from downhill running. Thirty-two runners (10 women, 22 men) were pair-matched and randomized to 1.425 g/day of ginger root or placebo for 5 days. A 40-minute downhill (-7.5%) run was completed on day 3...
October 9, 2018: Journal of Dietary Supplements
Mohammad Irfan Khan, Md Azizur Rahman, Mohammad Khalid, Mohammad Khushtar, Md Mujahid
Berberis aristata is used for the treatment of diabetes, piles, and liver diseases. As the drug is broadly used in Indigenous systems of medicine, it was designed to set the quality standards and antimicrobial potential for the stem bark of Berberis aristata. Botanical, physicochemical, pharmacotoxicological, fluorescence, microbial load, and phytochemical parameters of the stem bark were determined. High-performance thin-layer chromatography (HPTLC) was carried out by the CAMAG-HPTLC system. Berberine, total phenolics, and flavonoids were estimated...
October 5, 2018: Journal of Dietary Supplements
Bill I Campbell, Ross Perry, John Horsley, Danielle Aguilar, Taylor Shimshock, Carl Fox, Andres Vargas, Lauren Colenso-Semple
Males seeking to improve body composition may ingest thermogenic dietary supplements with the goal of elevating resting metabolic rate. The purpose of this study was to examine the effects of a commercially available dietary supplement (containing ingredients that promote thermogenesis) on resting metabolic rate (RMR) in a randomized, double-blind, placebo-controlled cross-over study. Ten healthy, physically active males (age: 26.5 ± 6.4 years; height: 177.6 ± 7.2 cm; body weight: 80.5 ± 10...
October 5, 2018: Journal of Dietary Supplements
B O Ajiboye, H O B Oloyede, M O Salawu
The antidiabetic activity of Triticum aestivum seed-based diet on alloxan-induced diabetic rats was investigated. Forty-eight male and female albino rats of four groups were used for this study. Rats were sacrificed on day 28 and organs of interest were excised. Triticum aestivum seed-based diet significantly (p < .05) reversed the levels of fasting blood glucose, albumin, globulin, bilirubin, urea, creatinine, Na+ , and K+ . In addition, diabetic rats fed Triticum aestivum seed-based diet had significantly (p < ...
October 4, 2018: Journal of Dietary Supplements
H Reginald McDaniel, Christopher LaGanke, Laura Bloom, Sharon Goldberg, Lucas C Lages, Laura A Lantigua, Steven E Atlas, Judi M Woolger, John E Lewis
Multiple sclerosis (MS) is a progressive neurodegenerative disease associated with increased infection rates, chronic inflammation, and premature death. Optimization of nutritional status via dietary supplementation may improve immune function in people suffering from MS and lead to decreased rates of infection. Fifteen individuals with a diagnosis of relapsing-remitting MS for an average of 12.4 years (SD =7.4; R = 2, 25) were enrolled in a one-year open-label clinical trial. Participants consumed a broad-spectrum dietary supplement regimen containing polysaccharides, phytochemicals, antioxidants, vitamins, and minerals three times per day...
October 4, 2018: Journal of Dietary Supplements
Neil A Schwarz, Sarah K McKinley-Barnard
Multi-ingredient preworkout supplements (MIPS) are marketed as a means to increase exercise performance. The purpose of this study was to determine the effect of a single serving of Bang Pre-Workout Master Blaster (BMB) on upper- and lower-body power output and local muscular endurance. Ten resistance-trained males participated in two exercise testing sessions consisting of the vertical jump (VJ), seated medicine ball throw (SMBT), and local muscular endurance tests for the bench press (BP) and leg extension (LE) exercises at 70% of one-repetition maximum...
October 4, 2018: Journal of Dietary Supplements
Lina Begdache, Hamed Kianmehr, Cassandra V Heaney
Dietary supplement (DS) use is increasing among college students. Early adulthood is a critical developmental stage when behavioral trends are established with potential health implications. Many studies have suggested a proper college education on DSs is needed, but no follow-up reports exist in the literature. The purpose of the study was to compare DS use in college students with and without a formal education on DSs. An anonymous survey was sent over electronic mailing lists of different social and professional student groups, including students in the health and wellness studies (HWS) minor (HM) at Binghamton University...
September 25, 2018: Journal of Dietary Supplements
(no author information available yet)
No abstract text is available yet for this article.
November 2, 2018: Journal of Dietary Supplements
Tooba Naz Shamsi, Romana Parveen, Sumbul Afreen, Mudasser Azam, Priyankar Sen, Yamini Sharma, Qazi Mohd Rizwanul Haque, Tasneem Fatma, Nikhat Manzoor, Sadaf Fatima
Protease inhibitors are one of the most promising and investigated subjects for their role in pharmacognostic and pharmacological studies. This study aimed to investigate antioxidant, anti-inflammatory, and antimicrobial activities of trypsin inhibitors (TIs) from two plant sources (Cajanus cajan and Phaseolus limensis). TI was purified from C. cajan (PUSA-992) by ammonium sulfate precipitation followed by ion exchange chromatography. TI from Phaseolus limensis (lima bean trypsin inhibitor; LBTI) was procured from Sigma-Aldrich, St...
November 2, 2018: Journal of Dietary Supplements
William Y Boadi, Andrew Lo
Obesity has been reported to be a risk factor for some types of cancer, such as prostate and lung. The AKT or PI3K-AKT is a signal transduction pathway that promotes survival and growth in response to extracellular signals. The aim of this study was to investigate the effects of two flavonoids, quercetin and kaempferol, and exogenous glutathione (GSH) on the expressions of phospho- and total-AKT levels in 3T3-L1 preadipocytes. Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) levels were measured in the treated samples and used as the internal standard...
November 2, 2018: Journal of Dietary Supplements
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