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Journal of Dietary Supplements

Luca Piemontese
Wine by-products, in particular grape pomace, can be an important source of polyphenols and dietary fibers and are increasingly being used as a starting material in the industrial production of plant food supplements, such as other matrices containing biomolecules, with antioxidant properties. The risk associated with the consumption of these products was recently analyzed through a study of potential genotoxic and carcinogenic compounds that can be found in the marketed products. In particular, occurrence data about contamination with the mycotoxin ochratoxin A were also reported...
November 28, 2016: Journal of Dietary Supplements
Alireza Naderi, Mehdi Sadeghi, Amir Sarshin, Vahid Imanipour, Seyed Ali Nazeri, Fatemeh Farkhayi, Mark E T Willems
Muscle carnosine is an intracellular buffer. The intake of β-alanine, combined with carbohydrate and protein, enhanced carnosine loading in human muscle. The aim of the present study was to examine if muscle carnosine loading was enhanced by β-alanine intake and co-ingestion of glucose in male rats. Thirty-six male rats were divided into three groups and supplemented for four weeks: β-alanine (βA group, 1.8% β-alanine in drinking water), β-alanine and glucose (βAGL group, 1.8% β-alanine and 5% glucose in drinking water), and control (C group, drinking water)...
November 4, 2016: Journal of Dietary Supplements
Ganiyu Oboh, Omodesola O Ogunruku, Sunday I Oyeleye, Tosin A Olasehinde, Ayokunle O Ademosun, Aline Augusti Boligon
This study investigated the inhibitory effects of phenolic-rich extracts from Clerodendrum volubile leaves on cholinergic [acetylcholinesterase (AChE) and butyrylcholinesterase (BChE)] and monoaminergic [monoamine oxidase (MAO)] enzymes' activities and pro-oxidants [Fe(2+) and quinolinic acid-(QA)] induced lipid peroxidation in rats brain homogenates in vitro. Free phenolic extracts (FPE) and bound phenolic extracts (BPE) were obtained via solvent extraction, and the total phenol and flavonoid contents were evaluated...
October 18, 2016: Journal of Dietary Supplements
Amir Hadi, Makan Pourmasoumi, Marzieh Kafeshani, Jahangir Karimian, Mohammad Reza Maracy, Mohammad Hasan Entezari
OBJECTIVE: Additional oxygen consumption during intense exercises may lead to oxidative stress and contribute to muscular fatigue. Green tea and sour tea (Hibiscus sabdariffa L.), which contain various flavonoids and polyphenols, have many healthful properties such as anticarcinogenic, anti-inflammatory, and heart protecting effects. The aim of the present study was to assess the effects of green tea and sour tea supplementation on oxidative stress and muscle damage in soccer athletes...
October 13, 2016: Journal of Dietary Supplements
Jolene Zheng, Chenfei Gao, Mingming Wang, Phuongmai Tran, Nancy Mai, John W Finley, Steven B Heymsfield, Frank L Greenway, Zhaoping Li, David Heber, Jeffrey H Burton, William D Johnson, Roger A Laine
Epidemiological studies indicate that the increased consumption of sugars including sucrose and fructose in beverages correlate with the prevalence of obesity, type-2 diabetes, insulin resistance, hyperinsulinemia, hypertriglyceridemia, and hypertension in humans. A few reports suggest that fructose extends lifespan in Saccharomyces cerevisiae. In Anopheles gambiae, fructose, glucose, or glucose plus fructose also extended lifespan. New results presented here suggest that fructose extends lifespan in Caenorhabditis elegans (C...
September 28, 2016: Journal of Dietary Supplements
Todd C Rideout, Scott V Harding, Amy Raslawsky, Curtis B Rempel
Resistant starch (RS) has been well characterized for its glycemic control properties; however, there is little consensus regarding the influence of RS on blood lipid concentrations and lipoprotein distribution and size. Therefore, this study aimed to characterize the effect of daily RS supplementation in a controlled capsule delivery on biomarkers of cardiovascular (blood lipids, lipoproteins) and diabetes (glucose, insulin) risk in a pig model. Twelve 8-week-old male Yorkshire pigs were placed on a synthetic Western diet and randomly divided into two groups (n = 6/group) for 30 days: (1) a placebo group supplemented with capsules containing unmodified pre-gelatinized potato starch (0 g/RS/day); and (2) an RS group supplemented with capsules containing resistant potato starch (10 g/RS/day)...
September 21, 2016: Journal of Dietary Supplements
Tim N Ziegenfuss, Hector L Lopez, Jennifer E Sandrock, A William Kedia, Scott Habowski, Chad Kerksick
Using a prospective, randomized, double-blind, crossover study design, fifteen healthy male (n = 8) and female (n = 7) participants (mean ± standard deviation (SD): 28.3 ± 6.1 yr, 176.3 ± 11.4 cm, 89.8 ± 21.7 kg, 28.5 ± 4.8 kg/m(2)) completed this study. Two testing sessions occurred after an overnight fast and refraining from physical exercise. Prior to and 60, 120, and 180 minutes after single dose ingestion of placebo (PLA) or a Thermogenic Supplement (TS), visual analog scales (VAS), resting metabolic rate (VO2), and venous blood were collected...
September 9, 2016: Journal of Dietary Supplements
Margarita Sala, Lauren Breithaupt, Cynthia M Bulik, Robert M Hamer, Maria C La Via, Kimberly A Brownley
PURPOSE: Chromium treatment has been shown to improve glucose regulation in some populations. The purpose of this study was to evaluate whether chromium picolinate (CrPic) supplementation improves glucose regulation in overweight individuals with binge-eating disorder (BED). METHODS: In this double-blinded randomized pilot trial, participants (N = 24) were randomized to high (HIGH, 1000 mcg/day, n = 8) or moderate (MOD, 600 mcg/day, n = 9) dose of CrPic or placebo (PL, n = 7) for 6 months...
March 4, 2017: Journal of Dietary Supplements
(no author information available yet)
No abstract text is available yet for this article.
November 2016: Journal of Dietary Supplements
Mohaddese Mahboubi
Ferula gummosa with the Persian name of Barijeh is reputed due to its traditional history. The aim of this review was to investigate traditional and novel applications of this valuable plant. Relevant databases (PubMed, ScienceDirect®, Wiley, Taylor & Francis, and Springer) and local books on ethnopharmacology of F. gummosa were studied without limitation up to January 1, 2015, and the results of these studies were collected and reviewed. F. gummosa has been traditionally used as an antiseptic, an anti-flatulent, an anti-seizure agent, an anti-spasm, a pain killer, an inflammation reliever, and a tonic of memory enhancement...
November 2016: Journal of Dietary Supplements
Maryam Mohammadi, Amir Avan, Marzieh Emamian, Abolfazl Khajavi-Rad, Malihe Aghasizadeh-Sharbaf, Maryam Tayefi, Habibollah Esmaeili, Davoud Zomorrodian, Mohsen Moohebati, Mahmoud Ebrahimi, Mohsen Nematy, Mahmoud Reza Azarpazhooh, Mina Mousavi, Fatemeh Daneshmand, Gordon A Ferns, Mohammad Reza Parizadeh, Majid Ghayour-Mobarhan
PURPOSE: We have investigated the association between markers of renal function [serum urea nitrogen, creatinine, and estimated glomerular filtration rate (eGFR)] and age and lipid profile in an Iranian population sample of 4,567 subjects. MATERIALS/METHODS: Serum creatinine and urea nitrogen, together with anthropometric parameters and lipid profile were determined in all the subjects. eGFR was calculated using the modification of diet in renal disease formula...
November 2016: Journal of Dietary Supplements
Neetu Mishra, Dileep Kumar, Syed Ibrahim Rizvi
Increased oxidative stress has been shown to play an important role in the etiology and pathogenesis of diabetes and its complications. Abelmoschus esculentus (Okra) has been reported to possess many important biological properties. We undertook in vivo studies on male Wistar rats to examine the antioxidative potential of okra in normal and alloxan-treated diabetic rats. Okra extract was administered to control and diabetic rats for 35 consecutive days. Erythrocyte plasma membrane redox system (PMRS) activity (p < 0...
November 2016: Journal of Dietary Supplements
Pattaneeya Prangthip, Aikkarach Kettawan, Juthathip Posuwan, Masaaki Okuno, Tadashi Okamoto
This study explored effects of ubiquinol-10 and ubiquinone-10, two different forms of coenzyme Q10, in diabetic rats. Oxidative stress is characterized by the depletion of antioxidant defenses and overproduction of free radicals that might contribute to, and even accelerate, the development of diabetes mellitus (DM) complications. Coenzyme Q10 was administered orally to diabetic rats and oxidative stress markers were then assessed. Bioavailability in normal rats was additionally assessed in various tissues and subcellular fractions after short-term and long-term coenzyme Q10 supplementation...
November 2016: Journal of Dietary Supplements
Anna Giulia Falchi, Ilaria Grecchi, Chiara Muggia, Giuseppina Palladini, Stefano Perlini
The beneficial effects of soluble fibers on carbohydrate metabolism are well documented. In this regard, we tested an arabinoxylan-enriched white bread flour, obtained by a patented process by which the bran extracted from the milling process is enzymatically hydrolyzed in order to separate the soluble fraction fiber from the insoluble fiber. We recruited 24 healthy normoglycemic volunteers [Age 34-61 ± 12.5 y; Body Mass Index (BMI) 22.1 ± 2.5 kg/m(2); Waist circumference (WC) 84.43 ± 8.0 cm; Fat Mass (FM) 22...
November 2016: Journal of Dietary Supplements
Stuti Pandey, Aditya Ganeshpurkar, Divya Bansal, Nazneen Dubey
Amaranthus cruentus (Amaranthaceae) is one of the popularly grown leafy vegetables in the Indian subcontinent. Leaves of the plant are rich in polyphenols, tannins, flavonoids, steroids, terpenoids, saponins, and betalains. The plant also contains rich amounts of protein, calcium, iron, vitamins A, E, and C, and folic acid. The present work was undertaken to evaluate the antianemic effect of Amaranthus cruentus. Ethanol extract of Amaranthus cruentus was prepared. Acute oral toxicity of the extract was determined by Organization for Economic Cooperation and Development (OECD) Guideline 423...
November 2016: Journal of Dietary Supplements
Stephen A Butler, Laurence A Cole
Trend diets can be commonplace amongst those who are trying to lose weight but in most cases there is some shred of evidence to suggest they might be of some benefit. Seldom is there a diet which is such a fad that it is not only completely unfounded but also potential harmful. The human chorionic gonadotropin or "hCG diet" is such a diet, which after half a century still has no evidence to support its efficacy; in fact all scientific publications subsequent to the original article counter these claims. In this short communication, we review the literature and present data on exactly what some of the hCG diet preparations actually contain and highlight that, based on current data, these may do more harm than good...
November 2016: Journal of Dietary Supplements
Zeinab Nikniaz, Reza Mahdavi, Leila Nikniaz, Aliasghar Ebrahimi, Alireza Ostadrahimi
In the present randomized double-blinded placebo-controlled study, the effect of Elaeagnus angustifolia L. (EA) whole fruit and medulla powders on anthropometric indices, serum lipid profile, and atherogenic indices in females with knee osteoarthritis (OA) was investigated. Ninety females with mild to moderate knee osteoarthritis were randomly assigned to one of three groups-medulla powder, whole fruit powder, or placebo. The subjects received 15 g/day of medulla powder of EA, whole fruit powder of EA, or placebo...
November 2016: Journal of Dietary Supplements
Fatema ElAmrawy, Ghada ElAgouri, Ola Elnoweam, Samar Aboelazayem, ElMohanad Farouk, Mohamed I Nounou
Erectile dysfunction prevalence globally is noticeably high. This is accompanied by an increase in the use of nutraceuticals for male enhancement. However, the global market is invaded by counterfeit and adulterated nutraceuticals claimed to be of natural origin sold with a therapeutic claim. The objective of this article is to review male enhancement nutraceuticals worldwide with respect to claim, adulterants, and safety. The definition of such products is variable across countries. Thus, the registration procedures differ as well...
November 2016: Journal of Dietary Supplements
Mannanthendil Kumaran Asha, Debnath Debraj, Shekhar Dethe, Anirban Bhaskar, Nithyanantham Muruganantham, Mundkinajeddu Deepak
Flavonoid-rich extract prepared from Glycyrrhiza glabra has been found to be beneficial in patients with functional dyspepsia and was reported to possess some gut health-promoting properties such as antioxidant, anti-inflammatory and anti-Helicobacter pylori activities. In the present study, the flavonoid-rich extract of Glycyrrhiza glabra was evaluated for its compatibility with probiotic strains (Lactobacillus casei, Lactobacillus fermentum, Lactobacillus plantarum, and Streptococcus thermophilus), commercial probiotic drinks, and digestive enzymes (pancreatic α-amylase, α-glucosidase, phytase, xylanase, and pancreatic lipase)...
September 2, 2016: Journal of Dietary Supplements
Arnetta Fletcher, Haiqiu Huang, Lu Yu, Quynhchi Pham, Liangli Yu, Thomas T Y Wang
Dietary supplements are widely used in the United States, but the safety issue remains unresolved. Immuno-deficient or immuno-compromised patients, estimated to exceed 10 million in the United States, are known to use dietary supplements. This population potentially may be susceptible to supplements' adverse effects. The cruciferous vegetable-derived indole-3-carbinol (I3C) is known for its possible protective effects against a number of chronic diseases and is commercially available as a dietary supplement...
August 31, 2016: Journal of Dietary Supplements
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