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BMC Veterinary Research

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https://www.readbyqxmd.com/read/29162115/opportunities-for-topical-antimicrobial-therapy-permeation-of-canine-skin-by-fusidic-acid
#1
Sian-Marie Frosini, Ross Bond, Anette Loeffler, Jo Larner
BACKGROUND: Staphylococcal infection of the canine epidermis and hair follicle is amongst the commonest reasons for antimicrobial prescribing in small animal veterinary practice. Topical therapy with fusidic acid (FA) is an attractive alternative to systemic therapy based on low minimum inhibitory concentrations (MICs, commonly <0.03 mg/l) documented in canine pathogenic staphylococci, including strains of MRSA and MRSP (methicillin-resistant Staphylococcus aureus and S. pseudintermedius)...
November 21, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/29162104/elimination-kinetics-of-eugenol-in-grass-carp-in-a-simulated-transportation-setting
#2
Dong-Hao Zhao, Chang-Liang Ke, Qi Liu, Xu-Feng Wang, Qiang Wang, Liu-Dong Li
BACKGROUND: Fish are vulnerable to stress from over-crowding during transportation and eugenol is the most common sedative used to minimize fish injury. The ADI value of 2.5 mg/kg is recommended by the Joint FAO/WHO Expert Committee on Food Additives. The aim of this work was to study the elimination kinetics of eugenol following exposure of grass carp to a eugenol bath in a simulated transportation setting. RESULTS: Grass carp, Ctenopharyngodon idella (120 fish) were exposed for 24 h to a 10 mg/L eugenol bath...
November 21, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/29157237/isolation-and-identification-of-culturable-fungi-from-the-genitals-and-semen-of-healthy-giant-pandas-ailuropoda-melanoleuca
#3
Xiaoping Ma, Changcheng Li, Jiafa Hou, Yu Gu
BACKGROUND: In order to better understand the possible role of fungi in giant panda reproduction and overall health, it is important to provide a baseline for the normal fungal composition in the reproductive system. Using morphology and internal transcribed spacer (ITS) sequence analysis, we systematically isolated and identified fungal species from the vagina, foreskin, and semen of 21 (11 males and 10 females) healthy giant pandas to understand the normal fungal flora of the genital tracts...
November 21, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/29149900/immunogenic-potential-of-a-salmonella-typhimurium-live-vaccine-for-pigs-against-monophasic-salmonella-typhimurium-dt-193
#4
Tobias Theuß, Elke Ueberham, Jörg Lehmann, Thomas Lindner, Sven Springer
BACKGROUND: Monophasic Salmonella Typhimurium (mSTM) strains account for up to 8.6% of all human Salmonellosis cases. They have an increasing prevalence during recent years and several human cases with hospitalisation were reported. These strains are often isolated from pigs and pork - one primary source of human infection. A Salmonella Typhimurium (STM) live vaccine has been proven successful in controlling of STM infections in pigs for many years. The aim of this study was to test the immunogenicity of the vaccine in weaners during oral challenge with a virulent mSTM strain and to examine the kinetics of STM-specific IgA, IgM and IgG antibodies induced by vaccination and infection...
November 17, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/29149886/antibiotic-susceptibility-profiles-of-mycoplasma-synoviae-strains-originating-from-central-and-eastern-europe
#5
Zsuzsa Kreizinger, Dénes Grózner, Kinga M Sulyok, Kristin Nilsson, Veronika Hrivnák, Dušan Benčina, Miklós Gyuranecz
BACKGROUND: Mycoplasma synoviae causes infectious synovitis and respiratory diseases in chickens and turkeys and may lead to egg shell apex abnormalities in chickens; hence possesses high economic impact on the poultry industry. Control of the disease consists of eradication, vaccination or medication. The aim of the present study was to determine the in vitro susceptibility to 14 different antibiotics and an antibiotic combination of M. synoviae strains originating from Hungary and other countries of Central and Eastern Europe...
November 17, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/29145844/development-and-evaluation-of-an-interferon-gamma-assay-for-the-diagnosis-of-tuberculosis-in-red-deer-experimentally-infected-with-mycobacterium-bovis
#6
María Ángeles Risalde, Jobin Thomas, Iker Sevilla, Miriam Serrano, Jose Antonio Ortíz, Joseba Garrido, Mercedes Domínguez, Lucas Domínguez, Christian Gortázar, Jose Francisco Ruíz-Fons
BACKGROUND: Red deer (Cervus elaphus) is regarded as an epidemiologically relevant host for Mycobacterium bovis (M. bovis) and closely related members of the Mycobacterium tuberculosis complex that cause animal tuberculosis (TB). The standard antemortem screening test for the detection of TB in deer is the intradermal tuberculin skin test, but the detection of interferon-gamma (IFNγ) produced by white blood cells exposed to M. bovis antigens can be used as an alternative or supplemental assay in most TB eradication/control programs...
November 16, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/29145838/mri-characteristics-for-phantom-scratching-in-canine-syringomyelia
#7
Zoe R Nalborczyk, Angus K McFadyen, Jelena Jovanovik, Anna Tauro, Colin J Driver, Noel Fitzpatrick, Susan P Knower, Clare Rusbridge
BACKGROUND: A classic sign of canine syringomyelia (SM) is scratching towards one shoulder. Using magnetic resonance imaging (MRI) we investigate the spinal cord lesion relating to this phenomenon which has characteristics similar to fictive scratch secondary to spinal cord transection. Medical records were searched for Cavalier King Charles spaniels with a clinical and MRI diagnosis of symptomatic SM associated with Chiari-like malformation (CM). The cohort was divided into SM with phantom scratching (19 dogs) and SM but no phantom scratching (18 dogs)...
November 16, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/29141638/diffusion-weighted-imaging-of-the-brains-of-dogs-with-idiopathic-epilepsy
#8
Antje Hartmann, Steffen Sager, Klaus Failing, Marion Sparenberg, Martin J Schmidt
BACKGROUND: Idiopathic epilepsy is one of the most common neurological disorders in dogs. Unfortunately, up to 30% of dogs with idiopathic epilepsy show no improvement under antiepileptic drug treatment. Diffusion-weighted imaging is used in human medicine to identify epileptogenic foci in the brain to allow for more invasive treatments such as deep brain stimulation or surgical removal. The aim of this study was to ass the feasibility of interictal diffusion-weighted MRI in dogs and to evaluate the distribution of diffusion in the brains of dogs with idiopathic epilepsy (IE) and to compare these values to previously published values from healthy beagle dogs...
November 15, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/29141637/molecules-produced-by-probiotics-prevent-enteric-colibacillosis-in-pigs
#9
Ricardo Nordeste, Akalate Tessema, Sapana Sharma, Zlatko Kovač, Chuan Wang, Rocio Morales, Mansel William Griffiths
BACKGROUND: With the advent of antimicrobial resistance in animal pathogens, novel methods to combat infectious diseases are being sought. Among these, probiotics have been proposed as a means of promoting animal health but problems with their use has been reported. Research has demonstrated that bioactive molecules produced during the growth of certain probiotics interfere with bacterial cell-to-cell communication, which consequently results in an attenuation of virulence in a number of pathogens, including E...
November 15, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/29141631/detection-of-rabbit-haemorrhagic-disease-virus-2-during-the-wild-rabbit-oryctolagus-cuniculus-eradication-from-the-berlengas-archipelago-portugal
#10
F A Abade Dos Santos, C Carvalho, Oliveira Nuno, J J Correia, M Henriques, M C Peleteiro, M Fevereiro, M D Duarte
BACKGROUND: In the regular wildlife monitoring action carried out in the summer of the past few years at the Berlenga Island, wild rabbits (Oryctolagus cuniculus) have been repeatedly found dead. However, the origin of those deaths was never investigated. Our aim was to investigate the cause of death of 11 rabbits collected between April and May 2016. RESULTS: While screening samples from rabbit carcasses for the major viral rabbit pathogens, five tested positive to RHDV2 but all were negative for RHDV and myxoma virus (MYXV)...
November 15, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/29141628/gene-expression-analyses-of-the-small-intestine-of-pigs-in-the-ex-evacuation-zone-of-the-fukushima-daiichi-nuclear-power-plant
#11
Motoko Morimoto, Ayaka Kato, Jin Kobayashi, Kei Okuda, Yoshikazu Kuwahara, Yasushi Kino, Yasuyuki Abe, Tsutomu Sekine, Tomokazu Fukuda, Emiko Isogai, Manabu Fukumoto
BACKGROUND: After the accident at the Fukushima Daiichi Nuclear Power Plant, radioactive contaminants were released over a widespread area. Monitoring the biological effects of radiation exposure in animals in the ex-evacuation zone should be continued to understand the health effects of radiation exposure in humans. The present study aimed to clarify the effects of radiation by investigating whether there is any alteration in the morphology and gene expressions of immune molecules in the intestine of pigs and inobuta (wild boar and domestic pig hybrid) in the ex-evacuation zone in 2012...
November 15, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/29141627/in-vitro-properties-of-concentrated-canine-platelets-stored-in-two-additive-solutions-a-comparative-study
#12
N Hlavac, C S Lasta, M L Dalmolin, L A Lacerda, D de Korte, N A Marcondes, S R Terra, F B Fernandes, F H D González
BACKGROUND: Platelet transfusion therapy poses many challenges in veterinary clinical practice. Lack of readily available blood donors, short shelf-life, and inability to administer a sufficient number of platelets to meet a dog's transfusion need are the major difficulties encountered. Platelet additive solutions are already in use at American and European human blood banks, showing to be a realistic alternative. This study compares the in vitro platelet function in plasma, Composol, or SSP+ during storage for 13 days...
November 15, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/29141625/microrna-profiling-of-dogs-with-transitional-cell-carcinoma-of-the-bladder-using-blood-and-urine-samples
#13
Michael S Kent, Allison Zwingenberger, Jodi L Westropp, Laura E Barrett, Blythe P Durbin-Johnson, Paramita Ghosh, Ruth L Vinall
BACKGROUND: Early signs of canine transitional cell carcinoma (TCC) are frequently assumed to be caused by other lower urinary tract diseases (LUTD) such as urinary tract infections, resulting in late diagnosis of TCC which could be fatal. The development of a non-invasive clinical test for TCC could dramatically reduce mortality. To determine whether microRNAs (miRNAs) can be used as non-invasive diagnostic biomarkers, we assessed miRNA expression in blood and/or urine from dogs with clinically normal bladders (n = 28), LUTD (n = 25), and TCC (n = 17)...
November 15, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/29132371/survey-of-vector-borne-agents-in-feral-cats-and-first-report-of-babesia-gibsoni-in-cats-on-st-kitts-west-indies
#14
Patrick John Kelly, Liza Köster, Jing Li, Jilei Zhang, Ke Huang, Gillian Carmichael Branford, Silvia Marchi, Michel Vandenplas, Chengming Wang
BACKGROUND: As there is little data on vector-borne diseases of cats in the Caribbean region and even around the world, we tested feral cats from St Kitts by PCR to detect infections with Babesia, Ehrlichia and spotted fever group Rickettsia (SFGR) and surveyed them for antibodies to Rickettsia rickettsii and Ehrlichia canis. RESULTS: Whole blood was collected from apparently healthy feral cats during spay/ neuter campaigns on St Kitts in 2011 (N = 68) and 2014 (N = 52)...
November 13, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/29132368/frequency-of-canine-nt230-del4-mdr1-mutation-in-prone-pure-breeds-their-crosses-and-mongrels-in-israel-insights-from-a-worldwide-comparative-perspective
#15
Yaron Dekel, Yossy Machluf, Aviad Stoler, Arava Aderet, Daniel Baumel, Efrat Kellerman, Yoram Plotsky, Oshrat Noked Partouche, Gal Elhalal, Izhar Ben-Shlomo, Dani Bercovich
BACKGROUND: Sensitivity to macrocyclic lactones, which are commonly used in veterinary clinics, was first found in Rough Collies, and was attributed in 2001 to a 4 bp deletion in the MDR1 gene. The list of affected breeds currently includes 13 breeds. Researchers from different countries and continents examined the allelic frequencies of the nt230(del4) MDR1 mutation, emphasizing the clinical importance of this test not only to mutation-prone dogs, but also to their crosses and mongrels, since treatment of a deletion carrier with these compounds may lead to its death...
November 13, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/29132350/avian-infectious-bronchitis-virus-disrupts-the-melanoma-differentiation-associated-gene-5-mda5-signaling-pathway-by-cleavage-of-the-adaptor-protein-mavs
#16
Liping Yu, Xiaorong Zhang, Tianqi Wu, Jin Su, Yuyang Wang, Yuexin Wang, Baoyang Ruan, Xiaosai Niu, Yantao Wu
BACKGROUND: Melanoma differentiation associated gene 5 (MDA5) and retinoic acid-inducible gene-I (RIG-I) selectively sense cytoplasmic viral RNA to induce an antiviral immune response. Infectious bronchitis virus (IBV) is one of the most important infectious agents in chickens, and in chicken cells, it can be recognized by MDA5 to activate interferon production. RIG-I is considered to be absent in chickens. However, the absence of RIG-I in chickens raises the question of whether this protein influences the antiviral immune response against IBV infection...
November 13, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/29126424/salivary-ph-calcium-phosphorus-and-selected-enzymes-in-healthy-dogs-a-pilot-study
#17
Ilaria Iacopetti, Anna Perazzi, Tamara Badon, Silvia Bedin, Barbara Contiero, Rebecca Ricci
BACKGROUND: Saliva in dogs, as in humans, is a complex fluid secreted by different salivary glands in the oral cavity to protect the oral mucosa and teeth. The use of saliva as a substitute for blood in diagnosing and prognosticating disease in humans is widely accepted. Salivary biochemistry has also been used as a marker for periodontal disease in humans. No studies have as yet investigated the relation between salivary biochemistry and periodontal disease in dogs, however; neither has the salivary composition of healthy dogs with no oral disease been assessed...
November 10, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/29126413/leaves-from-banana-musa-nana-and-maize-zea-mays-have-no-phyto-prophylactic-effects-on-the-susceptibility-of-grass-carp-ctenopharyngodon-idella-to-aeromonas-hydrophila-infection
#18
Richard Mayrhofer, Simon Menanteau-Ledouble, Johannes Pucher, Ulfert Focken, Mansour El-Matbouli
BACKGROUND: The ubiquitous and opportunistic bacterial pathogen Aeromonas hydrophila has been associated with ulcerative dermatitis in fish, especially under stressful conditions. It can cause severe losses in fresh water aquaculture and is particularly prevalent in tropical and subtropical regions. Fresh leaves from maize and bananas have been used as feed supplement by fish farmers in Vietnam and it has been reported that they may have phyto-prophylactic benefits. In the present study, a feeding trial was conducted to investigate the benefits of providing maize and banana leaves as feed supplement: to determine if they were taken up and digested by grass carp (Ctenopharyngodon idella), if this uptake resulted in improved growth performance, and if leaf supplementation protected fish when challenged with A...
November 10, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/29121941/the-nutritional-status-affects-the-complete-blood-count-of-goats-experimentally-infected-with-haemonchus-contortus
#19
S Cériac, C Jayles, R Arquet, D Feuillet, Y Félicité, H Archimède, J-C Bambou
BACKGROUND: Gastrointestinal nematode (GIN) remains the most important pathogenic constraint of small ruminant production worldwide. The improvement of the host immune response against GIN though breeding for improved animal resistance, vaccination and nutritional supplementation appear as very promising methods. The objective of this study was to investigate the effect of four nutritional status differing in protein and energy levels (Hay: 5.1 MJ/Kg of dry matter (DM) and 7.6% of crude protein (CP), Ban: 8...
November 9, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/29121939/case-definition-terminology-for-paratuberculosis-johne-s-disease
#20
R J Whittington, D J Begg, K de Silva, A C Purdie, N K Dhand, K M Plain
Paratuberculosis (Johne's disease) is an economically significant condition caused by Mycobacterium avium subsp. paratuberculosis. However, difficulties in diagnosis and classification of individual animals with the condition have hampered research and impeded efforts to halt its progressive spread in the global livestock industry. Descriptive terms applied to individual animals and herds such as exposed, infected, diseased, clinical, sub-clinical, infectious and resistant need to be defined so that they can be incorporated consistently into well-understood and reproducible case definitions...
November 9, 2017: BMC Veterinary Research
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