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Journal of Cancer Research and Therapeutics

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https://www.readbyqxmd.com/read/28230045/the-single-chest-tube-versus-double-chest-tube-application-after-pulmonary-lobectomy-a-systematic-review-and-meta-analysis
#1
REVIEW
Xuefei Zhang, Desheng Lv, Mo Li, Ge Sun, Changhong Liu
OBJECTIVE: Draining of the chest cavity with two chest tubes after pulmonary lobectomy is a common practice. The objective of this study was to evaluate whether using two tubes after a pulmonary lobectomy is more effective than using a single tube. PATIENTS AND METHODS: We performed a meta-analysis of five randomized studies that compared the single chest tube with double chest tube application after pulmonary lobectomy. The primary end-point was amount of drainage and duration of chest tube drainage...
December 2016: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28230044/a-meta-analysis-to-evaluate-the-diagnostic-value-of-dual-time-point-f-fluorodeoxyglucose-positron-emission-tomography-computed-tomography-for-diagnosis-of-pulmonary-nodules
#2
Ming Zhao, Yongfu Ma, Bo Yang, Yuqi Wang
OBJECTIVES: This meta-analysis aimed at evaluating the efficacy of dual-time-point (DTP) F-fluorodeoxyglucose (F-FDG) positron emission tomography/computed tomography (PET/CT) in diagnosing pulmonary nodules. METHODS: Using computer and manual search, the current research about the efficacy of DTP F-FDG PET/CT in diagnosing pulmonary nodules was collected. According to the evaluation criteria of Quality Assessment of Diagnostic Accuracy Studies Scale, the data from 13 studies were analyzed by Meta-DiSc software, and the sensitivity (Sen), specificity (Spe), diagnostic odds ratios (DOR), positive likelihood ratios (LR+), and negative likelihood ratios (LR-) were summarized...
December 2016: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28230043/does-smoking-increase-the-risk-of-developing-glioma-a-meta-analysis-based-on-case-control-studies
#3
Xiaqing Guo, Yabo Wang
OBJECTIVE: The purpose of this study was to assess the relationship between smoking and glioma risk by meta-analysis. MATERIALS AND METHODS: We have searched the databases of MEDLINE, EMBASE, Ovid, and CNKI to find the suitable studies related to association between smoking and glioma risk. The pooled odds ratio (OR) and 95% confidence interval (CI) of smokers in glioma patients compared to normal controls were aggregated by statistic software Stata11.0. The publication bias was evaluated by Begg's funnel plot...
December 2016: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28230042/meta-analysis-of-association-between-mobile-phone-use-and-glioma-risk
#4
Yabo Wang, Xiaqing Guo
OBJECTIVE: The purpose of this study was to evaluate the association between mobile phone use and glioma risk through pooling the published data. METHODS: By searching Medline, EMBSE, and CNKI databases, we screened the open published case-control or cohort studies about mobile phone use and glioma risk by systematic searching strategy. The pooled odds of mobile use in glioma patients versus healthy controls were calculated by meta-analysis method. The statistical analysis was done by Stata12...
December 2016: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28230041/gefitinib-single-drug-in-treatment-of-advanced-esophageal-cancer
#5
Yingjun Xu, Zhihui Xie, Yan Shi, Mengwei Zhang, Jia Pan, Yanming Li, Hong Lu
OBJECTIVE: The objective of this study is to evaluate the clinical efficacy and toxicity of gefitinib single drug in treatment of advanced esophageal cancer. MATERIALS AND METHODS: Forty-one case of advanced esophageal cancer were included from February 2012 to June 2016 in the Department of Oncology, Huaihe Hospital of Henan University. All of the included 41 cases were pathology or cytology confirmed of esophageal cancer with advanced stage with previously chemotherapy regimen of cisplatin or fluorouracil...
December 2016: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28230040/ezrin-expression-in-the-primary-hepatocellular-carcinoma-patients-and-associated-with-clinical-pathological-characteristics
#6
Debiao Pan, Shi Wang, Hailin Ye, Shengqian Xu, Guanxiong Ye
OBJECTIVE: The aim of this study was to assess Ezrin expression in the primary hepatic carcinoma patients and associated with clinical, pathological characteristics. MATERIALS AND METHODS: Fifty-one patients with primary hepatocellular carcinoma (PHC) with completed clinical data were retrospectively analyzed in this study. The Ezrin expression in PHC and normal control liver tissue was tested by immunohistochemical assay. The Ezrin expression and relationship with clinical characteristics were evaluated...
December 2016: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28230039/cyclooxygenase-2-expression-and-association-with-skin-cancer-a-meta-analysis-based-on-chinese-patients
#7
Lu Shujiao, Han Lilin, Shi Yong
OBJECTIVE: The purpose of this meta-analysis was to evaluate the association between cyclooxygenase-2 (Cox-2) expression and skin cancer. MATERIALS AND METHODS: We searched the databases of PubMed, CNKI, and WANFANG to find the case-control studies associated with Cox-2 expression and skin cancer. The association between Cox-2 expression and skin cancer was demonstrated by odds ratio (OR) and its 95% confidence interval (95% CI). The publication bias was evaluated by funnel plot and Egger's line regression test...
December 2016: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28230038/association-between-hepatitis-b-virus-hepatitis-c-virus-infection-and-primary-hepatocellular-carcinoma-risk-a-meta-analysis-based-on-chinese-population
#8
Libo Li, Xiaolin Lan
OBJECTIVE: To assess the relationship between hepatitis B virus (HBV), hepatitis C virus (HCV), and HBV/HCV double infection and hepatocellular carcinoma risk in Chinese population. MATERIALS AND METHODS: The databases of PubMed and CNKI were electronic searched by reviewers according to the searching words of HBV, HCV, and hepatocellular carcinoma. The related case-control studies or cohort studies were included. The association between virus infection and hepatocellular carcinoma risk was demonstrated by odds ratio (OR) and 95% confidence interval (95% CI)...
December 2016: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28230037/mutl-homolog-1-expression-in-thyroid-carcinoma-and-its-clinical-significance
#9
Yi Lu, Baocheng Jiang, Ye Yuan, Jianping Fei, Jiyuan Wang
OBJECTIVE: The aim of this study was to evaluate the MutL homolog 1 (MLH1) protein expression in thyroid cancer patients and its association with clinical pathological characteristics. MATERIALS AND METHODS: Forty thyroid cancer tissues and 22 partial paired normal thyroid tissues from 40 thyroid cancer patients who received surgery were collected in this study. MLH1 protein expression was tested by immunohistochemical method for the 40 cancer tissues and 22 partial paired normal thyroid tissues...
December 2016: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28230036/single-lumen-tracheal-ventilation-for-minimally-invasive-esophagectomy-in-patients-with-esophageal-cancer
#10
Yu Bai, Yi Zhou, Xi Hua Lu
OBJECTIVE: The aim of this study was to observe the efficacy and safety of single-lumen tracheal ventilation for esophageal cancer surgery. METHODS: Thirty-eight patients with esophageal carcinoma who prepared for minimally invasive esophagectomy were included in this study. All of the included 38 patients were received single-lumen tracheal ventilation. The arterial blood gas index was monitored through the operation procedure and recorded at four-time points: before induction (T0), at the end of chest operation (T1), at the end of the abdominal operation (T2), and 30 min after extubation (T3)...
December 2016: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28230035/a-meta-analysis-of-contrast-enhanced-ultrasound-for-small-hepatocellular-carcinoma-diagnosis
#11
Huadong Deng, Hongwei Shi, Jianming Lei, Yan Hu, Gang Li, Chaojun Wang
OBJECTIVE: To discuss the efficacy of contrast-enhanced ultrasound (CEUS) for diagnosis of small hepatocellular carcinoma (HCC) by pooling the open published data. METHODS: A comprehensive publication electronic search was performed by reviewers in the databases of PubMed, Embase, Web of Science, and China National Knowledge Infrastructure. The open published studies about CEUS for small HCC diagnosis were collected. The sensitivity, specificity, positive likelihood ratio (+LR), negative likelihood ratio (-LR), and diagnostic odds ratio (DOR) were pooled by stata 12...
December 2016: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28230034/effect-of-dezocine-combined-with-propofol-on-painless-gastroscopy-in-patients-with-suspect-gastric-carcinoma
#12
Ji Ma, Peng Zhang, Yixuan Zhang, Zong Chen, Wenqi Xin, Donghang Zhang, Chuangeng Ma
OBJECTIVE: To evaluate the effect of dezocine combined with propofol on painless gastroscopy in patients with suspect gastric carcinoma. METHODS: Forty-three patients with gastric carcinoma who have underwent painless gastroscopy were retrospectively analyzed. For the 43 patients, 21 patients received propofol 1 mg/kg for painless gastroscopy (control group) and other 22 cases received dezocine 20 µg/kg plus propofol 1 mg/kg for painless gastroscopy (experiment group)...
December 2016: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28230033/postoperative-infectious-complications-after-liver-resection-for-hepatocellular-carcinoma
#13
Yuan Zhao, Yi Jin, Yueming Wu
OBJECTIVE: The purpose of this study was to evaluate the postoperative infectious complications after liver resection for hepatocellular carcinoma by logistic regression analysis. MATERIALS AND METHODS: One hundred and sixty-six hepatocellular carcinoma patients who received surgery were retrospectively reviewed and included in this study. Of the included 166 patients, 42 patients had the postoperative infectious complications (case group) and other 124 patients did not develop postoperative infection (control group)...
December 2016: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28230032/x-ray-cross-complementing-groups-1-rs1799782-c-t-polymorphisms-and-colorectal-cancer-susceptibility-a-meta-analysis-based-on-chinese-han-population
#14
Liming Wang, Junfeng Qian, Chunxiao Ying, Yongwei Zhuang, Xingjie Shang, Fang Xu
OBJECTIVE: X-ray cross-complementing groups 1 (XRCC1) rs1799782 C>T polymorphisms and colorectal cancer susceptibility were not clear. The purpose of this study was to evaluate the association between XRCC1 rs1799782 C>T polymorphisms and colorectal cancer susceptibility by meta-analysis. MATERIALS AND METHODS: Related databases of Medline, CNKI, and Wanfang were systematic searched for the studies related to XRCC1 rs1799782 C>T polymorphisms and colorectal cancer risk in Chinese Han population...
December 2016: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28230031/serum-pro-gastrin-releasing-peptide-in-diagnosis-of-small-cell-lung-cancer-a-meta-analysis
#15
Hongyuan Wang, Junfeng Qian
OBJECTIVE: The purpose of this study was to assess the diagnostic sensitivity and specificity for serum pro-gastrin-releasing peptide (Pro-GRP) in diagnosis of small cell lung cancer (SCLC) through pooling all the open published data. MATERIALS AND METHODS: Databases of PubMed, Cochrane, ISI Web of Knowledge, and CNKI were electronic, searched by two reviewers to find the diagnostic study serum Pro-GRP in diagnosis of SCLC. The diagnostic sensitivity, specificity, positive likelihood ratio (PLR), negative likelihood ratio (NLR), diagnostic odds ratio (DOR), and area under the receiver operating characteristic (ROC) were calculated by Med DiSc1...
December 2016: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28230030/the-predictive-value-of-cervical-lymph-node-metastasis-through-sentinel-lymph-node-biopsy-in-patients-with-oral-cancer-a-meta-analysis
#16
Ren Lin, Junjie Yan, Weidong Liu, Tonghai Fan, Liujun Tang
OBJECTIVE: The purpose of this meta-analysis was to evaluate the predictive value of cervical lymph node metastasis through sentinel lymph node biopsy (SLNB) in patients with oral cancer. MATERIALS AND METHODS: Two authors independently searched the databases of PubMed, Cochrane central register of controlled trials, EMBASE, and CNKI to find the potential suitable diagnostic study related to SLNB. The diagnostic sensitivity, specificity, positive likely hood ratio (+LR), negative likely hood ratio (-LR), diagnostic odds ratio (DOR) were pooled by Meta-DiSc1...
December 2016: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28230029/clinical-efficacy-and-safety-of-gemcitabine-plus-nedaplatin-in-the-treatment-of-advanced-nasopharyngeal-carcinoma
#17
Yan Hu, Jiang Tao Fu, Dongmei Shi, Biao Feng, Zhichao Shi
OBJECTIVE: The purpose was to explore the clinical effects and safety of gemcitabine plus nedaplatin in the treatment of advanced nasopharyngeal carcinoma. MATERIALS AND METHODS: From March 2014 to August 2015, we recruited 63 advanced nasopharyngeal carcinoma patients in our hospital. Moreover, the 62 cases were randomly divided into control group (n = 31) and treatment group (n = 32). Patients in the control groups were treated with 5-fluorouracil 500 mg/m 2 + 500 ml 0...
December 2016: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28230028/leucine-rich-repeats-and-immunoglobulin-like-domains-protein-1-and-fascin-actin-bundling-protein-1-expression-in-nonsmall-cell-lung-cancer
#18
Juanjuan Zhang, Xiaoyan Wang, Yijie Zhang, Jingcan Wu, Nannan Zhou
OBJECTIVE: To assess the clinical significance of leucine-rich repeats and immunoglobulin-like domains protein 1 (LRIG1) and fascin actin-bundling protein 1 (Fascin-1) expression in nonsmall cell lung cancer (NSCLC). MATERIALS AND METHODS: Six-one NSCLC patients were included in this study. The expression of LRIG1 and Fascin-1 was assayed in the tumor tissue and relative normal lung tissue of the 61 NSCLC patients by immunohistochemistry. The relationship between LRIG1, Fascin-1 expression pattern and lung cancer patients' clinical pathology characteristics was evaluated...
December 2016: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28230027/a-meta-analysis-of-elemene-versus-ddp-intrapleural-injection-in-the-treatment-of-malignant-pleural-effusion-caused-by-lung-cancer
#19
Xiaolong Wang, Haojie Wang, Li Li
OBJECTIVE: The objective of this study was to evaluate the clinical efficacy of elemene versus DDP intrapleural injection in the treatment of malignant pleural effusion caused by lung cancer by meta-analysis. MATERIALS AND METHODS: PubMed (1960 ~ 2016.4), EMBASE (1980 ~ 2016.4), and CNKI (1979 ~ 2016.4) databases were searched to identify the clinical studies of elemene intrapleural injection in the treatment of lung cancer malignant pleural effusion. The odds ratio (OR) was used to evaluate the clinical efficacy of elemene in the treatment of pleural effusion compared to cisplatin (DDP)...
December 2016: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28230026/the-diagnostic-value-of-contrast-enhanced-computed-tomography-imaging-for-detection-of-colorectal-tumors-a-meta-analysis
#20
Qing Yu, Jie Liu
OBJECTIVE: To evaluate the application usage of contrast-enhanced computer tomography imaging for colorectal tumors diagnosis. METHODS: By searching the Medline and CNKI databases, we collected all diagnostic tests about contrast-enhanced CT imaging for colorectal tumors. Sensitivity and specificity were calculated to evaluate the usage of individual diagnostic tests. The data were analyzed using statistic software Meta-DiSc 1.4. RESULTS: Nine trials that included a total of 4797 patients were analyzed in this study...
December 2016: Journal of Cancer Research and Therapeutics
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