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Journal of Cancer Research and Therapeutics

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https://www.readbyqxmd.com/read/29578187/primary-renal-synovial-sarcoma-a-case-report-and-literature-review
#1
Yong Huang, Dawei Liu, Junhang Luo, Wei Chen
Synovial sarcomas (SSs) are very rare, poorly studied tumors that generally occurs around joint and muscle tendons. Primary SSs of the kidney are even rarer, accounting for <2% of all malignant renal tumors. We report the case of a 44-year-old man who was diagnosed with primary renal SS on the basis of imaging, histopathological, and immunohistochemical examination. We also present a comprehensive review of the literature, with a focus on the differential diagnosis and treatment of renal tumors.
2018: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/29578186/contrast-enhanced-ultrasound-imaging-characteristics-of-malignant-transformation-of-a-localized-type-gallbladder-adenomyomatosis-a-case-report-and-literature-review
#2
Xiao-Chen Shi, Shao-Shan Tang, Wei Zhao
Gallbladder adenomyomatosis (GAM) is an acquired, reactive, tumor-like condition. Malignant transformation is extremely rare, and imaging features during contrast-enhanced ultrasound (CEUS) have not been described before. Herein, we describe a 73-year-old Asian man who had been diagnosed with gallbladder carcinoma by conventional ultrasonography (US). Based on additional radiological findings, we believed that it was a localized adenomyomatosis. However, the histopathological diagnosis was adenocarcinoma originate from adenomyomatosis with serosal invasion...
2018: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/29578185/hypofractionated-postoperative-irradiation-in-localized-renal-cell-cancer-a-case-report-and-pertinent-literature-review
#3
Xiang-Rong Zhao, Guang-Lian Shan, Yong Zhang, Yong-Hua Yu
For localized the incidence of renal cell carcinoma (RCC), nephrectomy is the standard treatment. As RCC is generally regarded as a radiation-resistant tumor, the value of postoperative adjuvant radiotherapy is controversial. However, with new advance in radiotherapy (i.e., three-dimensional conformal radiation therapy [3DCRT] and intensity-modulated radiation therapy [IMRT]), target volume delineation, intensity modulation in treatment planning, and treatment delivery are more accurate with fewer adverse effect...
2018: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/29578184/uterine-metastases-originating-from-a-pulmonary-inflammatory-myofibroblastic-tumor
#4
Jun Zhang, Yuehong Li, Lei Lou
Pulmonary inflammatory myofibroblastic tumor (IMT) is a rare mesenchymal tumor, and is considered an inflammatory pseudotumor. Here, we report of a 37-year-old woman with severe cough and stridor who was diagnosed with primary IMT of the lungs, with adenocarcinoma in situ based on the pathology in December 2012. A year later, transabdominal ultrasonography demonstrated a solid mass in the uterine wall that was initially diagnosed as a leiomyoma. However, postoperative histological examination and immunohistochemical staining revealed it as a uterine metastasis of the lung IMT...
2018: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/29578183/four-case-reports-on-pelvic-tumors-with-deep-venous-thromboses-as-main-symptoms-and-literature-review
#5
Cheng Liu, Dingfeng Li, Jun Guo, Qiu Cui, Linlin Zhang, Yanjun Zeng
To probe into the reasons for misdiagnoses of pelvic tumor as deep venous thromboses as well as the diagnostic methods and effective treatments on pelvic tumor. Four case reports on misdiagnosing pelvic tumor as deep venous thromboses and further analysis on the causes of misdiagnosis, diagnosis, and treatment with the literature study. The four cases were misdiagnosed as pelvic tumor, which actually were fibroneuroma, myxo.fluidity liposarcoma, moderately differentiated squamous cell carcinoma, and synovial sarcoma, respectively...
2018: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/29578182/diffuse-large-b-cell-lymphoma-with-concurrent-hepatitis-b-virus-infection-in-the-mabthera-era-unique-clinical-features-and-worse-outcomes
#6
Xiao Yan, Miao Zhou, Zhongze Lou, Qitian Mu, Lixia Sheng, Ping Zhang, Yi Wang, Guifang Ouyang
Aim of Study: Hepatitis B virus (HBV) infection is a risk factor in diffuse large B-cell lymphoma (DLBCL); however, little is known other than the prevalence evidence. In addition, the impact of HBV infection to DLBCL remains controversial. The purpose of this study was to investigate the HBV infection status of 136 patients with DLBCL, analyze the clinical property of HBV-infected patients, and determine the effects of HBV infection to the outcomes of DLBCL patients. Materials and Methods: A retrospective analysis was performed in our center from January 2007 to December 2014...
2018: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/29578181/identification-of-key-genes-related-to-high-risk-gastrointestinal-stromal-tumors-using-bioinformatics-analysis
#7
Shuan Jin, Wenhua Zhu, Jun Li
Aim: The purpose of this study was to identify predictive biomarkers used for clinical therapy and prognostic evaluation of high-risk gastrointestinal stromal tumors (GISTs). Materials and Methods: In this study, microarray data GSE31802 were used to identify differentially expressed genes (DEGs) between high-risk GISTs and low-risk GISTs. Then, enrichment analysis of DEGs was conducted based on the gene ontology and kyoto encyclopedia of genes and genomes pathway database...
2018: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/29578180/effect-of-lenalidomide-on-the-human-gastric-cancer-cell-line-sgc7901-vincristine-notch-signaling
#8
Wanjun Ding, Tao Zeng, Weiping Tao, Wei Ge, Junjian Deng, Hongbo Lei, Yong Xiao, Fei Liao
Aim of Study: To examine the function of lenalidomide (LEN) on the human multidrug resistance (MDR)-type gastric cancer line SGC7901/vincristine (VCR) via regulating Notch signaling. Materials and Methods: Quantitative polymerase chain reaction was used for checking the genes of Notch, DNA methyltransferase (DNMT), RBP-J, Hes1/5, Deltex1, MDR/multidrug resistant protein (MRP); the cell proliferation and cell death were detected by cell counting kit-8 (CCK8) staining, Ki-67 expression, and propidium-iodide staining, and methylated DNA immunoprecipitation assay (MeDIP) was used for checking the 5 mC enrichment, indicating the DNA methylation of the Notch2 gene loci...
2018: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/29578179/-solanum-nigrum-polysaccharide-inhibits-tumor-growth-in-h22-bearing-mice-through-regulation-of-caspase-3-and-bcl-2
#9
Yueyan Huang, Manxiang Yin, Linlin Pan, Qian Yu, Qifeng Zhu, Weizhen Xu, Baoyue Ding, Yanping Ji, Jifang Zhou
Objective: The objective of this study was to investigate the effect of Solanum nigrum polysaccharides (SNPs) on tumor growth in H22 hepatocarcinoma cells bearing mice and explore the mechanism by focusing on the regulation of the expression of caspase-3 and bcl-2. Materials and Methods: Totally, 50 mice bearing with H22 cells were randomly divided into five groups: Model group, cyclophosphamide group (CTX, 30 mg/kg), SNP groups with low, medium, and high doses of SNP (30, 60, and 120 mg/kg)...
2018: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/29578178/comparison-of-short-course-with-long-course-preoperative-neoadjuvant-therapy-for-rectal-cancer-a-meta-analysis
#10
Ke Chen, Guoming Xie, Qi Zhang, Yanping Shen, Taoqi Zhou
Aim: This study attempted to compare the prognostic performance of short- and long-course preoperative treatments for neoadjuvant therapy of rectal cancer by meta-analysis. Methods: Electronic databases of PubMed and Embase were searched for eligible studies updated to February 29, 2016. Studies were included based on several predefined inclusion criteria. Quality assessment was carried out according to the Cochrane Collaboration recommendations in Cochrane handbook...
2018: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/29578177/the-clinical-benefit-of-epidermal-growth-factor-receptor-and-human-epidermal-growth-factor-receptor-2-targeted-agents-adding-to-endocrine-therapy-in-hormone-receptor-positive-breast-cancer
#11
Huan Li, Qing Zhai, Bo Yu
Objectives: Studies have suggested that the crosstalk between estrogen receptor and ErbB receptor is involved in endocrine therapy (ET) resistance, which might be overcome by drugs-targeting ErbB receptor. However, the results of clinical studies remain controversial. The aim of this meta-analysis was to evaluate the efficacy and safety of ErbB (mainly epidermal growth factor receptor and human epidermal growth factor receptor 2 [HER2]) inhibitors added to ET for hormone receptor-positive breast cancer patients...
2018: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/29578176/applications-of-nerve-stimulator-guided-thoracic-paravertebral-nerve-block-plus-general-anesthesia-in-small-incision-lung-cancer-surgery
#12
Pengfei Lei, Shan Gao, Peishan Wang, Jiefang Fan, Xiting Ai
Objective: The aim of the study was to investigate the application of nerve stimulator-guided thoracic paravertebral nerve block (TPVB) plus general anesthesia (GA) in small-incision lung cancer surgery. Methods: Forty patients scheduled for small-incision lung cancer surgery, the American Society of Anesthesiologists Grade I-II, were randomized into a TPVB-GA group (Group P) and a GA group (Group G), with 20 cases in each group. The dosage of general anesthetic, mean arterial pressure (MAP) at each time point, and heart rate (HR) of the two groups were recorded...
2018: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/29578175/tox-high-mobility-group-box-family-member-3-rs3803662-and-breast-cancer-risk-a-meta-analysis
#13
Lin Li, Guangcheng Guo, Fang Wang, Pengwei Lv, Mingzhi Zhu, Yuanting Gu, Mingli Han, Xinhong Pei
Aims: Some studies suggested that TOX high mobility group box family member 3 (TOX3) rs3803662 polymorphism was associated with the risk of breast cancer. However, the results were controversy. Therefore, in order to derive a more comprehensive estimation of the association between TOX3 rs3803662 polymorphism and breast cancer risk, we conducted a meta-analysis to investigate this relationship. Materials and Methods: An electronic literature search was conducted using the following database: PubMed, EMBASE, and China National Knowledge Infrastructure till to March 31, 2015...
2018: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/29578174/effects-of-continued-psychological-care-toward-brain-tumor-patients-and-their-family-members-negative-emotions
#14
Ning Xiao, Dan Zhu, Shuiyuan Xiao
Purpose: Numerous studies have confirmed that brain tumor patients and their family members frequently exhibit negative emotional reactions, such as anxiety and depression, during diagnosis and treatment of the disease. Family members experience increasing pressure as the year of survival of patient progress. The aim of this study was to investigate the effects of the continued psychological care (CPC) toward the brain tumor patients and their family members' emotions. Subjects and Methods: The asynchronous clinical control trial was performed, and 162 brain tumor patients and their family members were divided into the control group and the intervention group...
2018: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/29578173/guiding-values-of-multislice-spiral-computed-tomography-angiography-in-laparoscopic-d2-radical-gastrectomy-of-local-advanced-gastric-carcinoma
#15
Wang Chen, Jianbo Gao, Diansen Chen
Objective: This study aims to investigate the application values of preoperative multislice spiral computed tomography angiography (MSCTA) in laparoscopic radical resection of gastric carcinoma (GC). Materials and Methods: A total of 108 GC patients were divided into Groups I (i.e., where preoperative MSCTA was performed; n = 60) and II (i.e., where preoperative MSCTA was not performed; n = 48). Surgery was performed by the same group of surgeons. Results: Seven cases of blood vascular variation were detected in Group I during surgery, whereas four cases were detected in Group II...
2018: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/29578172/effect-of-bevacizumab-combined-with-chemotherapy-at-different-sequences-in-the-gastric-cancer-bearing-nude-mice
#16
Yalei Lv, Lina Song, Liang Chang, Xiaolin Zhang, Yan Liu, Wei Liu
Objective: To observe changes in the growth of fluorescence-labelled tumour cells in nude mice using small animal in vivo imaging technology and to compare the anti-tumour effects of the administration of bevacizumab monoclonal antibodies combined with chemotherapy at different time sequences. Materials and Methods: Different time sequences of administration of bevacizumab monoclonal antibodies combined with the 5-fluorouracil and cisplatin (FP) chemotherapy regimen were used for intervention treatment of tumour growth in a subcutaneous xenograft model of human gastric cancer in nude mice...
2018: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/29578171/effect-of-smoking-on-high-grade-cervical-cancer-in-women-on-the-basis-of-human-papillomavirus-infection-studies
#17
Jian-Hong Fang, Xue-Mei Yu, Shu-Hong Zhang, Yan Yang
Purpose: We aimed, in the present study, to measure the risk related to the high-grade cervical intraepithelial neoplasia grade 3 (CIN3) or worse (CIN3+) or worse/high-grade squamous intraepithelial lesions with respect to changes in human papillomavirus (HPV) and smoking status. Materials and Methods: A structured interview underwent for 7129 women. Then, we obtained their cervical cells and subjected to HPV testing. High-risk HPV infected and "no prevalent" cervical disease infected women were followed for cervical lesions up to 12 years (at baseline; n = 1531)...
2018: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/29578170/association-of-toll-like-receptors-with-the-risk-of-oral-squamous-cell-carcinoma
#18
Si-Lian Fang, Xiang-Bo Kong, Zhao-Qiang Zhang
Aim of Study: Association of toll-like receptors (TLRs) with the risk of oral squamous cell carcinoma (OSCC) from the published reports is still conflicting. This study was conducted to evaluate the relationship between TLRs and the risk of OSCC using meta-analysis method. Materials and Methods: The association studies were identified from PubMed and Cochrane Library on April 01 2015, and eligible investigations were included and synthesized using meta-analysis method...
2018: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/29578169/clinical-research-of-goal-directed-fluid-therapy-in-elderly-patients-with-radical-resection-of-bladder-cancer
#19
Tie-Jun Liu, Jin-Cun Zhang, Xiao-Zeng Gao, Zhi-Bin Tan, Jian-Jun Wang, Pan-Pan Zhang, Ai-Bin Cheng, Shu-Bo Zhang
Objective: The aim of this study is to investigate the clinical effect of goal-directed fluid therapy in elderly patients with radical resection of bladder cancer. Materials and Methods: Seventy-six elderly patients with radical resection of bladder cancer were selected from October 2012 to October 2014 and randomly divided into two groups, in which 38 patients received routine treatment as the control group and 38 patients received goal-directed fluid therapy based on routine treatment as the observation group...
2018: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/29578168/short-term-outcomes-after-transition-from-sweet-to-thoracoscopic-esophagectomy-our-experience-and-cost-analysis
#20
Fei Yao, Ju Yao, Fang Rong Hang, Shiqi Cao, Jun Ling Qian, Jian Wang
Objective: Thoracoscopic esophagectomy (TSE), as a minimally invasive technique, has obtained wide acceptance for treating esophageal cancer. In this study, we report our experience of the transfer from open sweet esophagectomy (OSE) to TSE and compare cost associated with the two approaches for esophageal cancer. Patients and Methods: Data were taken through a retrospective review of operative outcomes, complications and cost of 91 patients who underwent OSE or TSE for esophageal cancer from January 2012 to June 2014...
2018: Journal of Cancer Research and Therapeutics
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