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Néphrologie & Thérapeutique

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https://www.readbyqxmd.com/read/28216253/-atrial-fibrillation-and-anticoagulation-in-hemodialysis-patients-a-complex-decision
#1
Pierre Delanaye, Antoine Bouquegneau, Bernard E Dubois, Muriel Sprynger, Christophe Mariat, Jean-Marie Krzesinski, Patrizio Lancellotti
Cardiovascular mortality of hemodialysis patients remains a major problem. The prevalence and incidence of atrial fibrillation in this population are more important than in the general population. The indication of antivitamin K therapy (AVK) in this context of atrial fibrillation must be weighted against the increased risk of bleeding. Unfortunately, and contrary to the general population, an indication of anticoagulation based on embolic or hemorrhagic risk scores is not as clearly established in the hemodialysis population...
February 16, 2017: Néphrologie & Thérapeutique
https://www.readbyqxmd.com/read/28189486/central-retinal-vein-occlusion-in-a-patient-on-hemodialysis-secondary-to-antiphospholipid-syndrome-case-report
#2
Marouane Jabrane, Med Reda Ez-Zahraoui, Ibtissam Hajji, Wafaa Fadili, Abdeljalil Moutaouakil, Inass Laouad
Central retinal vein occlusion (CRVO) is one of the most common retinal vascular disease. Macular edema associated is responsible of the major decrease in visual acuity. The main causes often implicated are high blood pressure and diabetes. Other etiologies should be sought including CRVO secondary to antiphospholipid syndrome (APS). This rare etiology is associated with a poor prognosis when late diagnosed. Owing to the high associated mortality, early diagnosis and prompt treatment are necessary. We describe a case of APS complicated by a catastrophic antiphospholipid syndrome in a patient who presented a decrease visual acuity...
February 8, 2017: Néphrologie & Thérapeutique
https://www.readbyqxmd.com/read/28161267/-lower-limb-arterial-thrombosis-in-a-nephrotic-syndrome
#3
Raja Arrab, Aicha Bourrahouate, Mohamed Sbihi, Imane Ait Sab
Thromboembolic complications are frequent in the nephrotic syndrome. Arterial localizations have been rarely reported. There is no consensus on their management; it depends on the location and hypercoagulable state. We report a case of acute lower limb ischemia occurring in children with a history of nephrotic syndrome, complicated by toes necrosis. The diagnosis was made by Doppler ultrasonography. Thrombectomy was performed and the patient received an anticoagulant treatment. Local cares have improved the local state, avoiding surgical necrosectomy...
February 1, 2017: Néphrologie & Thérapeutique
https://www.readbyqxmd.com/read/28161266/clinical-spectrum-of-primary-hyperoxaluria-type%C3%A2-1-experience-of-a-tertiary-center
#4
Neveen A Soliman, Marwa M Nabhan, Safaa M Abdelrahman, Hanan Abdelaziz, Rasha Helmy, Khaled Ghanim, Hafez M Bazaraa, Ahmed M Badr, Omar A Tolba, Magd A Kotb, Khaled M Eweeda, Alaa Fayez
BACKGROUND AND AIM: Primary hyperoxalurias are rare inborn errors of metabolism resulting in increased endogenous production of oxalate that leads to excessive urinary oxalate excretion. Diagnosis of primary hyperoxaluria type 1 (PH1) is a challenging issue and depends on diverse diagnostic tools including biochemical analysis of urine, stone analysis, renal biopsy, genetic studies and in some cases liver biopsy for enzyme assay. We characterized the clinical presentation as well as renal and extrarenal phenotypes in PH1 patients...
February 1, 2017: Néphrologie & Thérapeutique
https://www.readbyqxmd.com/read/28161265/-reasons-for-first-consultation-in-nephrology-in-the-health-area-5-of-britanny-during-the-year-2014
#5
Jeanne Prévot, Sahar Bayat-Makoei, Cécile Vigneau
BACKGROUND: In France, the coordinated healthcare circuit means that patients should be referred to specialists, for example nephrologists, by another physician. However, there are no recommendations concerning the reasons justifying the referral to a nephrologist. The main purpose of our study is to describe the motif of first consultations in nephrology in the health area 5 of Brittany. METHODS: We retrospectively collected medical reports of first consultations by 17 nephrologists in the 4 centers of the study area, during the year 2014...
February 1, 2017: Néphrologie & Thérapeutique
https://www.readbyqxmd.com/read/28161264/ten-years-trends-in-renal-replacement-therapy-for-end-stage-renal-disease-in-mainland-france-lessons-from-the-french-renal-epidemiology-and-information-network-rein-registry
#6
Cécile Vigneau, Anne Kolko, Bénédicte Stengel, Christian Jacquelinet, Paul Landais, Philippe Rieu, Sahar Bayat, Cécile Couchoud
BACKGROUND: The incidence rate of renal replacement therapy (RRT) for end-stage renal disease (ESRD) is decreasing in several countries, but not in France. We studied the RRT trends in mainland France from 2005 to 2014 to understand the reasons for this discrepancy and determine the effects of ESRD management changes. METHODS: Data were extracted from the French Renal Epidemiology and Information Network registry. Time trends of RRT incidence and prevalence rates, patients' clinical and treatment characteristics were analysed using the Joinpoint regression program and annual percentage changes...
February 1, 2017: Néphrologie & Thérapeutique
https://www.readbyqxmd.com/read/28161263/the-measured-glomerular-filtration-rate-mgfr-before-and-6%C3%A2-months-after-bariatric-surgery-a-pilot-study
#7
Maëva Clerte, Sandra Wagner, Claire Carette, Albane Brodin-Sartorius, Éve Vilaine, Jean-Claude Alvarez, Emuri Abe, Charles Barsamian, Sébastien Czernichow, Ziad A Massy
INTRODUCTION: Over the last few decades, the prevalence of obesity has increased dramatically. This increase has been mirrored by a rise in the risk of a number of health conditions, including hypertension, diabetes and chronic kidney disease. Although the weight loss following bariatric surgery has been shown to relieve the severity of diabetes and reduce hypertension, the effect on renal function has been less extensively evaluated. OBJECTIVE: The aims of the present study were to: (i) compare the estimated glomerular filtration rate (eGFR, using the MDRD and CKD-EPI equations) and the calculated glomerular filtration rate (using the 24-hour urine volume) with the measured glomerular filtration rate (mGFR) assessed with the plasma iohexol clearance method in severely obese patients, and (ii) evaluate the effect of weight loss on the mGFR 6 months after bariatric surgery...
February 1, 2017: Néphrologie & Thérapeutique
https://www.readbyqxmd.com/read/28161262/-factors-affecting-the-choice-of-peritoneal-dialysis-perspective-of-patients-and-nephrologists
#8
Aida Habib, Anne-Claire Durand, Philippe Brunet, Ariane Duval-Sabatier, Olivier Moranne, Stanislas Bataille, Laurent Benhaim, Évelyne Bargas, Stéphanie Gentile
PURPOSE: To identify factors related to the choice of peritoneal dialysis as a first dialysis technique: the viewpoint of patients and viewpoint of nephrologists. METHODS: A retrospective multicenter study, type case-control was conducted in patients starting dialysis between 2010 and 2014 in 4 dialysis facilities in the PACA region. Nephrologists take care of patients included in the study were also interviewed. Data were collected using two standardized questionnaires: One for the patient and one for the nephrologists and using the French REIN registry...
February 1, 2017: Néphrologie & Thérapeutique
https://www.readbyqxmd.com/read/28159484/-lack-of-energy-in-a-patient-living-with-hiv
#9
Noémie Simon-Tillaux, Philippe Rouvier, Gilbert Deray, Corinne Isnard-Bagnis, Jérôme Tourret
No abstract text is available yet for this article.
January 31, 2017: Néphrologie & Thérapeutique
https://www.readbyqxmd.com/read/28159483/-at-every-dialysis-this-patient-suffered-angina-pectoris
#10
Jean-Pierre Potier, Daniel Moineau, Erdem Orberk
No abstract text is available yet for this article.
January 31, 2017: Néphrologie & Thérapeutique
https://www.readbyqxmd.com/read/28159482/obesity-and-kidney-disease-hidden-consequences-of-the-epidemic
#11
EDITORIAL
Csaba P Kovesdy, Susan Furth, Carmine Zoccali
No abstract text is available yet for this article.
January 31, 2017: Néphrologie & Thérapeutique
https://www.readbyqxmd.com/read/28110970/-plasma-exchange-in-nephrology-indications-and-technique
#12
Christophe Ridel, Sébastien Kissling, Laurent Mesnard, Alexandre Hertig, Éric Rondeau
Plasma exchange is a non-selective apheresis technique that can be performed by filtration or centrifugation allowing rapid purification of high molecular weight pathogens. An immunosuppressive treatment is generally associated to reduce the rebound effect of the purified substance. Substitution solutes such as human albumin and macromolecules are needed to compensate for plasma extraction. Compensation by viro-attenuated plasma is reserved solely for the treatment of thrombotic microangiopathies or when there is a risk of bleeding, because this product is very allergenic and expensive...
January 16, 2017: Néphrologie & Thérapeutique
https://www.readbyqxmd.com/read/28010941/-french-translation-of-the-clinical-practice-guideline-on-management-of-patients-with-diabetes-and-chronic-kidney-disease-stage%C3%A2-3b-or-higher-egfr-45ml-min-1-73%C3%A2-m-2
#13
Noémie Jourde-Chiche, Dominique Guerrot, Dominique Chauveau, Jean-Jacques Boffa
No abstract text is available yet for this article.
December 20, 2016: Néphrologie & Thérapeutique
https://www.readbyqxmd.com/read/27914916/-cytotoxicity-of-natural-anti-hla-antibodies-in-moroccan-patients-awaiting-for-kidney-transplantation
#14
Nadia Benseffaj, Sanae Ouadghiri, Asmaa Drissi Bourhanbour, Asmae Noor Zerrouki, Malika Essakalli
: The presence of anti-HLA antibodies in the serum of a patient result from an immune response produced during an immunizing event as transfusion, pregnancy or graft. These antibodies can be cytotoxic by activating the complement pathway via C1q and may cause organ rejection during the transplant. Some male patients awaiting kidney transplantation are seropositive for anti-HLA antibodies when they have no immunizing antecedent event. These antibodies are qualified as natural antibodies...
November 30, 2016: Néphrologie & Thérapeutique
https://www.readbyqxmd.com/read/28132672/place-des-%C3%A2-outils-embarqu%C3%A3-s-%C3%A2-bvm-et-btm-dans-la-prise-en-charge-de-la-surcharge-hydro-sod%C3%A3-e
#15
J-P Bourdenx, L Fartoux
No abstract text is available yet for this article.
December 2016: Néphrologie & Thérapeutique
https://www.readbyqxmd.com/read/28132671/d%C3%A3-bat-sur-l%C3%A2-%C3%A3-valuation-de-la-surcharge-hydro-sod%C3%A3-e-les-nouveaux-outils-sont-n%C3%A3-cessaires
#16
C Chazot, L Fartoux
No abstract text is available yet for this article.
December 2016: Néphrologie & Thérapeutique
https://www.readbyqxmd.com/read/28132670/d%C3%A3-bat-sur-l%C3%A2-%C3%A3-valuation-de-la-surcharge-hydro-sod%C3%A3-e-la-clinique-est-suffisante
#17
P Brunet, L Fartoux
No abstract text is available yet for this article.
December 2016: Néphrologie & Thérapeutique
https://www.readbyqxmd.com/read/28132669/les-enjeux-de-la-surcharge-hydro-sod%C3%A3-e
#18
F Vrtovsnik, L Fartoux
No abstract text is available yet for this article.
December 2016: Néphrologie & Thérapeutique
https://www.readbyqxmd.com/read/28132668/points-forts-du-1-er-congr%C3%A3-s-de-la-soci%C3%A3-t%C3%A3-francophone-de-n%C3%A3-phrologie-dialyse-et-transplantation-sfndt-%C3%A2-strasbourg-%C3%A2-du-4-au-7-octobre-2016
#19
L Fartoux
No abstract text is available yet for this article.
December 2016: Néphrologie & Thérapeutique
https://www.readbyqxmd.com/read/27825643/-sofosbuvir-and-daclatasvir-combination-therapy-in-hemodialysis-patient-with-liver-transplantation
#20
Mourad Hachicha, Danielle Botta-Fridlund
We report a case of sustained remission of a liver transplant patient infected with hepatitis C virus (HCV) genotype 1 undergoing hemodialysis treatment. Oral treatment regimen of the HCV infection consists of a combination of sofosbuvir 400 mg after each hemodialysis session and daclatasvir 60 mg daily, for a period of 3 months. Laboratory testing indicate that the combination regimen was well-tolerated with no sign of drug-drug interaction. Confirmation of these clinical observations in large clinical studies may help improve morbidity and decrease mortality outcome in patients infected with HCV and undergoing hemodialysis treatment...
December 2016: Néphrologie & Thérapeutique
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