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Clinical Otolaryngology

Carlos Torre, Stanley Yung-Chuan Liu, Clete A Kushida, Vladimir Nekhendzy, Leh-Kiong Huon, Robson Capasso
OBJECTIVES: The primary objective of the study was to understand the differential impact of Continuous Positive Airway Pressure (CPAP) on the location, degree, and pattern of airway collapse in Obstructive Sleep Apnea (OSA) patients utilizing Drug Induced Sleep Endoscopy (DISE). STUDY DESIGN: Non-randomized trial. SETTING: University Medical Center. PARTICIPANTS: 15 consecutive OSA patients undergoing DISE. MAIN OUTCOMES AND MEASURES: The patterns of airway collapse were videorecorded at baseline and under differential application of nasal CPAP (nCPAP) at 5,10, and 15 cm H2 O...
February 16, 2017: Clinical Otolaryngology
Darren Yap, Adam Shakir, Rhodri Costello, Simon Browning
Emergency department doctors and General Practitioners have a role in advising patients of their obligations to inform the DVLA regarding medical conditions that affect their ability to drive. Current guidelines are clear that the initial communication to the DVLA should be from the patient(1) . However, doctors should contact the DVLA directly if there are good reasons to do so(2) . Studies have shown that doctors' knowledge of medical restrictions placed on driving is poor (3,4,5,6) . Even if the need for a medical restriction is known, doctors are often not aware of the notification process...
February 16, 2017: Clinical Otolaryngology
C M Douglas, K Lang, W M Whitmer, J A Wilson, K Mackenzie
BACKGROUND: Tonsillitis is a common condition with an incidence in UK general practice of 37 per 1000 population a year(1) . Recurrent tonsillitis results in significant morbidity and impacts on individuals' quality of life. This study assesses the morbidity and quality of life of adults with recurrent tonsillitis, and the impact of surgical intervention on their health state. OBJECTIVES: 1.To describe disease specific and global quality of life for adults with recurrent tonsillitis six months after tonsillectomy, using two instruments: the Health Impact of Throat Problems (HITP) and EuroQol-visual analogue scale (EQ-VAS) questionnaire...
February 15, 2017: Clinical Otolaryngology
A W Hoey, N M Foden, S Hadjisymeou Andreou, F Noonan, A K Chowdhury, Greig S R, E L Sproson, D Allin, N Amin, K M Wouters, N E Jonas, D J Tweedie
OBJECTIVES: Intracapsular tonsillectomy (tonsillotomy) has been used internationally, mainly in the management of obstructive sleep apnoea, rather than recurrent tonsillitis, with little published data evaluating its use for this latter indication. We present long-term prospective data from 500 paediatric cases undergoing Coblation(®) intracapsular tonsillectomy, for both obstructive and infective indications. DESIGN: Prospective case series, March 2013-January 2016, all with completed follow up...
February 15, 2017: Clinical Otolaryngology
O H Ryu, J R Chao, M G Choi, C Kim, J-G Suh, Y Y Kim, C H Park, H-J Kim, J H Lee
1.We compared the hearing results of idiopathic sudden sensorineural hearing loss (ISSNHL) in normoglycemic patients versus those with pre-diabetes and diabetes mellitus (DM), including demographics and the impact of insulin administration. 2.The success rate for return of hearing in patients with DM was very high (80.0%) contrary to very low success rate for patients with pre-diabetes (38.2%). 3.High SD and MAGE in DM group could be explained by the effect of insulin and steroid treatment. 4.We believe the best explanation for the salutary impact of administration of insulin on hearing return was through reversal of ischemia 5...
February 8, 2017: Clinical Otolaryngology
C Aussedat, F Venail, Y Nguyen, E Lescanne, M Marx, D Bakhos
OBJECTIVES: Dissection of cadaveric temporal bones (TBs) is considered the gold standard for surgical training in otology. For many reasons, access to the anatomic lab and cadaveric TBs is difficult for some facilities. The aim of this prospective and comparative study was to evaluate the usefulness of a physical TB prototype for drilling training in residency. DESIGN: Prospective study. SETTING: Tertiary referral centre. PARTICIPANTS: Thirty-four residents were included...
February 7, 2017: Clinical Otolaryngology
Jong Chul Hong, Ji Won Seo, Ae Lan Jang, Sung Hwan Suh, Min Gyoung Pak, Seong Ho Han, Young Jin Park, Dong Kun Lee, Heon Soo Park, Myung Koo Kang
OBJECTIVES: This study is designed to evaluate the usefulness of intraoperative frozen section for the evaluation of microscopic extrathyroidal extension (ETE) in papillary thyroid carcinoma (PTC). DESIGN: Retrospective cohort study. SETTING: Dong-A University Medical Center, Busan, Korea PARTICIPANTS: Three hundred sixty-four patients who underwent thyroid surgery from January 2000 to December 2010, with PTC confined to one unilateral lobe as diagnosed using preoperative ultrasonography were enrolled...
February 6, 2017: Clinical Otolaryngology
Georg Haymerle, Lorenz Kadletz, Robert Wiebringhaus, Bahar Golabi, Michael Mildner, Dietmar Thurnher, Gregor Heiduschka
OBJECTIVES: Despite the excellent overall survival of 92-97% in early glottic cancer, recurrence rates of 13-20% have not improved in the last decades. The engulfment and cell motility protein 3 (ELMO3) has been described as prognostic marker in lung cancer patients. The aim of this study was to investigate the expression of ELMO3 in early laryngeal cancer patients treated with TLM and to evaluate its prognostic significance on clinical outcome. DESIGN, SETTING AND PARTICIPANT: 48 patients with glottic carcinoma (T1N0M0) that underwent primary treatment with TLM between 1994 and 2012 were analyzed...
February 6, 2017: Clinical Otolaryngology
Lidia Frejo, Eduardo Martin-Sanz, Roberto Teggi, Gabriel Trinidad, Andres Soto-Varela, Sofía Santos-Perez, Raquel Manrique, Nicolas Perez, Ismael Aran, Mario S Almeida-Branco, Angel Batuecas-Caletrio, Jesus Fraile, Juan M Espinosa-Sanchez, Vanesa Perez-Guillen, Herminio Perez-Garrigues, Manuel Oliva-Dominguez, Oscar Aleman, Jesus Benitez, Paz Perez, Jose A Lopez-Escamez
OBJECTIVES: To define clinical subgroups by cluster analysis in patients with unilateral Meniere disease (MD) and to compare them with the clinical subgroups found in bilateral MD. DESIGN: a cross-sectional study with a two-step cluster analysis. SETTINGS: a tertiary referral multicenter study. PARTICIPANTS: Nine hundred eighty-eight adult patients with unilateral MD. MAIN OUTCOME MEASURES: best predictors to define clinical subgroups with potential different etiologies...
February 6, 2017: Clinical Otolaryngology
Stacey T Gray, Lloyd P Hoehle, Katie M Phillips, David S Caradonna, Ahmad R Sedaghat
OBJECTIVE: In chronic rhinosinusitis (CRS), although patient-reported severity of sinonasal symptoms is significantly associated with diminishment of patients' general health-related quality of life (QOL), it remains unclear whether patient-perceived control of CRS symptomatology is associated with patients' QOL. In this study, we sought to determine the association between patient-perceived control of CRS symptomatology and QOL. DESIGN: Prospective cross-sectional study...
February 3, 2017: Clinical Otolaryngology
Mohamed T El Tabbakh, Mohamed Rifaat Ahmed, Yasser Taha Madian
Laryngeal carcinoma is considered as the most common head and neck neoplasm and the incidence of lymph node metastasis depends on the tumor stage. Sentinel Lymph Node Biopsy (SLNB) is an investigational tool in treatment of the clinical N0. The aim of the study is to determine the accuracy of sentinel lymph node biopsy (SLNB) in Laryngeal carcinoma and whether it can be used in the diagnostic and therapeutic approach to the clinical N0 neck. 47 patients were with Laryngeal carcinoma were divide into N0 group (20 patient) and N+ positive group (27 patients)...
February 3, 2017: Clinical Otolaryngology
Keun Ik Yi, Sangjeong Ahn, Do Youn Park, Jin-Choon Lee, Byung-Joo Lee, Soo-Geun Wang, Wonjae Cha
OBJECTIVES: Current preoperative diagnosis of thyroid nodules remains imperfect despite recent advances in cytopathology and molecular diagnostics. False-positivity in preoperative fine needle aspiration cytology (FNAC) may lead to overtreatment of patients, including total thyroidectomy, and sometimes to lawsuits for misdiagnosis and malpractice. In this study, we analyzed clinical characteristics and pathologic findings in patients with false-positivity for papillary thyroid carcinoma (PTC) in FNAC...
January 28, 2017: Clinical Otolaryngology
Sarah Jane Messeder, Forbes Lauder, Alison Kennedy, Georgios Kontorinis
It is estimated that hearing impairment affects 850,000 people in Scotland. In a tertiary, referral centre this number reflects over 32,000 of referrals to the department of audiology per annum. The number of referrals has increased reaching a plateau; in 2015 the number of referrals reached 32,422. The total number of hearing aid fittings carried out each year is on the rise. Within this tertiary centre covering eight hospitals and a catchment area of 1.16 million people, the annual cost of hearing aids exceeds £1...
January 28, 2017: Clinical Otolaryngology
Ye Qiu, Yanping Tang, Jianquan Zhang, Xiang Yi, Xiaoning Zhong, Guangnan Liu, Haiguang Xu, Yan Lei
1.Talaromyces marneffei, formerly known as Penicillium marneffei, usually affects the monocyte-macrophage system and can cause fatal systemic mycosis in immunocompromised individuals. This retrospective study is the first to describe the clinical and endoscopic (nasal endoscopy, flexible endoscopy) features of penicilliosis with pharynx and/or larynx infection in patients with acquired immunodeficiency syndrome (AIDS). 2.During the study period, 126 patients were diagnosed with penicilliosis. Among them, only seven who presented with culture and/or histopathological evidence of pharyngeal and/or laryngeal T...
January 28, 2017: Clinical Otolaryngology
M S Bajwa, C Tudur-Smith, R J Shaw, A G Schache
BACKGROUND: Fibrin sealants (FS) are commercially available products used in surgical wounds as adjuncts to haemostasis and closure of dead space. The role of FS in soft-tissue head and neck surgery has not been established. OBJECTIVES: To assess if FS improves wound related outcomes in patients undergoing soft-tissue surgery of the head and neck anatomical region that would commonly require a drain. TYPE OF REVIEW: Systematic review and meta-analysis of randomised controlled trials (RCTs)...
January 28, 2017: Clinical Otolaryngology
D Goff, S Coward, A Fitzgerald, V Paleri, J Moor, J M Patterson
OBJECTIVES: There is currently no consensus on the optimal feeding route for an oropharyngeal squamous cell cancer (OPSCC) patient without pre-existing dysphagia undergoing chemoradiotherapy (CRT). This study aims to compare the swallowing outcomes for OPSCC patients fed via either prophylactic RIG (pRIG) or reactive naso-gastric tube (rNGT). DESIGN: A prospective cohort study. SETTING: Four head and neck cancer centres in the North of England Cancer Network...
January 27, 2017: Clinical Otolaryngology
Grégoire B Morand, Sabrina D da Silva, Alex M Mlynarek, Martin J Black, Richard J Payne, Michael P Hier
OBJECTIVE: The extent of initial surgical management in papillary thyroid cancer (PTC) is controversial. We examined whether the presence of perioperative antithyroglobulin antibodies (TGA) could predict long-term recurrence and occurrence of adverse features among a homogenous group of PTC patients. METHODS: The clinical features of PTC patients treated at a single institution (Jewish General Hospital, McGill University, Montreal, Canada) were obtained from the medical records and all clinicopathologic information were reviewed...
January 27, 2017: Clinical Otolaryngology
E M Sielska-Badurek, M Sobol, A Cioch, E Osuch-Wójcikiewicz, A M Rzepakowska, K Niemczyk
OBJECTIVE: To translate and adapt the original Singing Voice Handicap Index (SVHI) for the Polish population and to evaluate the psychometric properties of the Polish SVHI version, such as internal consistency, reliability and construct validity in different groups of dysphonic singers. STUDY DESIGN: Prospective case-control study. SETTING: Patients treated at a single institute. PARTICIPANTS: Sixty singers with voice disorders and 57 healthy singers completed the SVHI and the Voice Handicap Index (VHI)...
January 20, 2017: Clinical Otolaryngology
Xiaohe Shen, Jizhao Yuan, Mengjie Zhang, Wenhua Li, Bing Ni, Yuzhang Wu, Li Jiang, Weiping Fan, Zhiqiang Tian
OBJECTIVES: Regulatory factors controlling stem cell identity and self-renewal are often active in aggressive cancers and are thought to promote cancer growth and progression. B-cell-specific transcription factor 3 (TCF3/E2A) is a member of the T-cell factor/lymphoid enhancer factor (TCF/LEF) transcription factor family that is central to regulating epidermal and embryonic stem cell identity. It has been reported that TCF3 was connected with the development and progression of a number of human cancers...
January 20, 2017: Clinical Otolaryngology
G M Jama, M Nosseir, J Danino, J Barraclough
No abstract text is available yet for this article.
January 19, 2017: Clinical Otolaryngology
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