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Clinics

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https://www.readbyqxmd.com/read/28355366/diagnostic-models-of-the-pre-test-probability-of-stable-coronary-artery-disease-a-systematic-review
#1
Ting He, Xing Liu, Nana Xu, Ying Li, Qiaoyu Wu, Meilin Liu, Hong Yuan
A comprehensive search of PubMed and Embase was performed in January 2015 to examine the available literature on validated diagnostic models of the pre-test probability of stable coronary artery disease and to describe the characteristics of the models. Studies that were designed to develop and validate diagnostic models of pre-test probability for stable coronary artery disease were included. Data regarding baseline patient characteristics, procedural characteristics, modeling methods, metrics of model performance, risk of bias, and clinical usefulness were extracted...
March 2017: Clinics
https://www.readbyqxmd.com/read/28355365/the-acceptability-of-vaginal-smear-self-collection-for-screening-for-cervical-cancer-a-systematic-review
#2
Natalia Serrano Doratioto Faria Braz, Noely Paula Cristina Lorenzi, Isabel Cristina Esposito Sorpreso, Lana Maria de Aguiar, Edmund Chada Baracat, José Maria Soares-Júnior
Cervical cancer is a major cause of death in adult women. However, many women do not undergo cervical cancer screening for the following reasons: fear, shame, physical limitations, cultural or religious considerations and lack of access to health care services. Self-collected vaginal smears maybe an alternative means of including more women in cervical cancer screening programs. The objective of this systematic review was to evaluate the acceptability of vaginal smear self-collection for cervical cancer screening...
March 2017: Clinics
https://www.readbyqxmd.com/read/28355364/sheep-model-for-uterine-transplantation-the-best-option-before-starting-a-human-program
#3
Wellington Andraus, Dani Ejzenberg, Rafael Miyashiro Nunes Dos Santos, Luana Regina Baratelli Carelli Mendes, Rubens Macedo Arantes, Edmund Chada Baracat, Luiz Augusto Carneiro D'Albuquerque
OBJECTIVE: This study reports the first four cases of a uterine transplant procedure conducted in sheep in Latin America. The aim of this study was to evaluate the success of uterine transplantation in sheep. METHOD: The study was conducted at Laboratory of Medical Investigation 37 (LIM 37) at the University of São Paulo School of Medicine. Four healthy mature ewes weighing 40-60 kg were used as both the donor and recipient for a transplant within the same animal (auto-transplant)...
March 2017: Clinics
https://www.readbyqxmd.com/read/28355363/the-effects-of-individually-ventilated-cages-on-the-respiratory-systems-of-male-and-female-wistar-rats-from-birth-until-adulthood
#4
Guilherme D'Aprile Marchesi, Sônia de Fatima Soto, Isac de Castro, Thiago Guimarães Rodrigues, Henrique Takachi Moriya, Francine Maria de Almeida, Rogerio Pazetti, Joel Claudio Heimann, Luzia Naôko Shinohara Furukawa
OBJECTIVE: To evaluate the respiratory systems of male and female rats maintained in individually ventilated cages (IVCs) from birth until adulthood. METHODS: Female Wistar rats were housed in individually ventilated cages or conventional cages (CCs) and mated with male Wistar rats. After birth and weaning, the male offspring were separated from the females and kept in cages of the same type until 12 weeks of age. RESULTS: The level of food consumption was lower in male offspring (IVC=171...
March 2017: Clinics
https://www.readbyqxmd.com/read/28355362/controlled-clinical-trial-addressing-teeth-whitening-with-hydrogen-peroxide-in-adolescents-a-12-month-follow-up
#5
Marcelo Mendes Pinto, Marcela Leticia Leal Gonçalves, Ana Carolina Costa da Mota, Alessandro Melo Deana, Silvia Regina Olivan, Carolina Bortoletto, Camila Haddad Leal de Godoy, Katia Lumi Tanikawa Vergilio, Olga Maria Altavista, Lara J Motta, Sandra Kalil Bussadori
OBJECTIVES: To evaluate the colorimetric change in incisors and canines of adolescents aged 12 to 20 years submitted to at-home whitening and to evaluate satisfaction, sensitivity and discomfort during the procedures through a questionnaire. METHOD: Thirty adolescents were randomly assigned to the following groups: 1) 6.0% hydrogen peroxide (White Class with calcium - FGM); 2) 7.5% hydrogen peroxide (White Class with calcium - FGM); 3) 10% hydrogen peroxide (Oral B 3D White - Oral-B); 4) Control group - placebo...
March 2017: Clinics
https://www.readbyqxmd.com/read/28355361/anaerobic-bacteria-in-the-intestinal-microbiota-of-brazilian-children
#6
Silvia T Talarico, Florenza E Santos, Katia Galeão Brandt, Marina B Martinez, Carla R Taddei
OBJECTIVE: Changes in the neonatal gut environment allow for the colonization of the mucin layer and lumen by anaerobic bacteria. The aim of the present study was to evaluate Bifidobacterium, Lactobacillus and Lactococcus colonization through the first year of life in a group of 12 Brazilian infants and to correlate these data with the levels of Escherichia coli. The presence of anaerobic members of the adult intestinal microbiota, including Eubacterium limosum and Faecalibacterium prausnitzii, was also evaluated...
March 2017: Clinics
https://www.readbyqxmd.com/read/28355360/helicobacter-pylory-infection-in-patients-with-esophageal-squamous-cell-carcinoma
#7
Omer Bilgehan Poyrazoglu, Ahmet Cumhur Dulger, Bilge Sumbul Gultepe
OBJECTIVE: Esophageal squamous cell carcinoma is one of the most common esophageal diseases in the developing world, but the relationship between esophageal squamous cell carcinoma and Helicobacter pylori infection remains a neglected topic. The primary objective of this study was to determine the association between Helicobacter pylori infection and esophageal squamous cell carcinoma. A second purpose was to determine the incidence and factors associated with Helicobacter pylori infection following esophagectomy...
March 2017: Clinics
https://www.readbyqxmd.com/read/28355359/oxidative-stress-and-immune-system-analysis-after-cycle-ergometer-use-in-critical-patients
#8
Eduardo Eriko Tenório de França, Luana Carneiro Ribeiro, Gabriela Gomes Lamenha, Isabela Kalline Fidelix Magalhães, Thainá de Gomes Figueiredo, Marthley José Correia Costa, Ubiracé Fernando Elihimas, Bárbara Luana Feitosa, Maria do Amparo Andrade, Marco Aurélio Valois Correia, Francimar Ferrari Ramos, Célia Maria Machado Barbosa de Castro
OBJECTIVE: The passive cycle ergometer aims to prevent hypotrophy and improve muscle strength, with a consequent reduction in hospitalization time in the intensive care unit and functional improvement. However, its effects on oxidative stress and immune system parameters remain unknown. The aim of this study is to analyze the effects of a passive cycle ergometer on the immune system and oxidative stress in critical patients. METHODS: This paper describes a randomized controlled trial in a sample of 19 patients of both genders who were on mechanical ventilation and hospitalized in the intensive care unit of the Hospital Agamenom Magalhães...
March 2017: Clinics
https://www.readbyqxmd.com/read/28355358/breast-conserving-surgery-in-locally-advanced-breast-cancer-submitted-to-neoadjuvant-chemotherapy-safety-and-effectiveness-based-on-ipsilateral-breast-tumor-recurrence-and-long-term-follow-up
#9
Guilherme Freire Angotti Carrara, Cristovam Scapulatempo-Neto, Lucas Faria Abrahão-Machado, Maria Mitzi Brentani, João Soares Nunes, Maria Aparecida Azevedo Koike Folgueira, René Aloisio da Costa Vieira
OBJECTIVE: To evaluate ipsilateral breast tumor recurrence after breast-conserving surgery for locally advanced breast cancer. METHODS: A retrospective observational cohort study was performed in patients with locally advanced breast cancer submitted to breast-conserving surgery after neoadjuvant chemotherapy based on an adriamycin-cyclophosphamide-paclitaxel regimen. We evaluated the clinical, pathologic, immunohistochemistry, and surgical factors that contribute to ipsilateral breast tumor recurrence and locoregional recurrence...
March 2017: Clinics
https://www.readbyqxmd.com/read/28355357/the-influence-of-body-image-on-surgical-decisions-in-adolescent-idiopathic-scoliosis-patients
#10
Paulo Alvim Borges, José Thomé de Carvalho, Olavo Biraghi Letaif, Raphael Martus Marcon, Alexandre Fogaça Cristante
OBJECTIVES: The objective of this study was to evaluate whether the severity of deformities in patients with adolescent idiopathic scoliosis contributes to patients' decision regarding whether to undergo an operation. METHODS: We evaluated body image factors in adolescent idiopathic scoliosis patients. We evaluated the magnitude of the main scoliotic curve, gibbosity (magnitude and location), shoulder height asymmetry and patient's age. We analyzed the correlation of these data with the number of years the patient was willing to trade for surgery, as measured by the time-trade-off method...
March 2017: Clinics
https://www.readbyqxmd.com/read/28273242/evaluation-of-tgf-%C3%AE-1-and-mcp-1-expression-and-tubulointerstitial-fibrosis-in-children-with-henoch-sch%C3%A3-nlein-purpura-nephritis-and-iga-nephropathy-a-clinical-correlation
#11
Zhao Shuiai, Shen Huijun, Gu Weizhong, Liu Aimin, Mao Jianhua
OBJECTIVES: Henoch-Schönlein purpura nephritis and immunoglobulin A nephropathy are two diseases with similar clinical presentations but very different prognoses. Transforming growth factor β1 and monocyte chemoattractant protein-1 have been associated with the development of tissue fibrosis. We examined the development of tubulointerstitial fibrosis and its relationship with Transforming growth factor β1 and monocyte chemoattractant protein-1 expression in these patients. METHODS: Renal tissue samples were collected by renal biopsy from 50 children with Henoch-Schönlein purpura nephritis and 50 children with immunoglobulin A nephropathy...
February 1, 2017: Clinics
https://www.readbyqxmd.com/read/28273241/pancreatic-necrosis-and-gas-in-the-retroperitoneum-treatment-with-antibiotics-alone
#12
Roberto Rasslan, Fernando da Costa Ferreira Novo, Marcelo Cristiano Rocha, Alberto Bitran, Manoel de Souza Rocha, Celso de Oliveira Bernini, Samir Rasslan, Edivaldo Massazo Utiyama
OBJECTIVE: To present our experience in the management of patients with infected pancreatic necrosis without drainage. METHODS: The records of patients with pancreatic necrosis admitted to our facility from 2011 to 2015 were retrospectively reviewed. RESULTS: We identified 61 patients with pancreatic necrosis. Six patients with pancreatic necrosis and gas in the retroperitoneum were treated exclusively with clinical support without any type of drainage...
February 1, 2017: Clinics
https://www.readbyqxmd.com/read/28273240/the-effect-of-laser-pan-retinal-photocoagulation-with-or-without-intravitreal-bevacizumab-injections-on-the-oct-measured-macular-choroidal-thickness-of-eyes-with-proliferative-diabetic-retinopathy
#13
Rony C Preti, Anibal Mutti, Daniel A Ferraz, Leandro C Zacharias, Yoshitaka Nakashima, Walter Y Takahashi, Mario L R Monteiro
OBJECTIVES: To investigate the effect of laser pan-retinal photocoagulation with or without intravitreal bevacizumab injections on macular choroidal thickness parameters in eyes with high-risk proliferative diabetic retinopathy. METHODS: High-risk proliferative diabetic retinopathy patients undergoing laser treatment were prospectively enrolled in this study. One eye was randomly selected for laser treatment combined with bevacizumab injections, study group, whereas the corresponding eye was subjected to laser treatment alone, control group...
February 1, 2017: Clinics
https://www.readbyqxmd.com/read/28273239/correlation-between-the-degree-of-correction-of-neuromuscular-scoliosis-and-patient-quality-of-life
#14
David Gonçalves Nordon, Ariel Falbel Lugão, Lucas Castrillon Carmo Machado, Raphael Martus Marcon, Alexandre Fogaça Cristante, Tarcísio Eloy Pessoa de Barros, Olavo Biraghi Letaif
OBJECTIVE: There are few data on patient satisfaction with surgery for the correction of neuromuscular scoliosis or on the correlation between patient satisfaction and the degree of curve correction achieved by surgery. Our aim was to determine the correlations between both patient satisfaction and perception of quality of life and the degree of curve correction. METHODS: We interviewed 18 patients and administered a questionnaire that collected social and economic data and information about functional ability, comorbidities and satisfaction...
February 1, 2017: Clinics
https://www.readbyqxmd.com/read/28273238/evaluation-of-self-perception-of-mechanical-ventilation-knowledge-among-brazilian-final-year-medical-students-residents-and-emergency-physicians
#15
Fernando Sabia Tallo, Simone de Campos Vieira Abib, Alexandre Jorgi de Andrade Negri, Paulo Cesar, Renato Delascio Lopes, Antônio Carlos Lopes
OBJECTIVE: To present self-assessments of knowledge about mechanical ventilation made by final-year medical students, residents, and physicians taking qualifying courses at the Brazilian Society of Internal Medicine who work in urgent and emergency settings. METHODS: A 34-item questionnaire comprising different areas of knowledge and training in mechanical ventilation was given to 806 medical students, residents, and participants in qualifying courses at 11 medical schools in Brazil...
February 1, 2017: Clinics
https://www.readbyqxmd.com/read/28273237/effects-of-diazoxide-in-experimental-acute-necrotizing-pancreatitis
#16
Roberta de Oliveira Andrade, Tiago Kunitake, Marcia Kiyomi Koike, Marcel C C Machado, Heraldo Possolo Souza
OBJECTIVE: We aimed to assess the effects of diazoxide on the mortality, pancreatic injury, and inflammatory response in an experimental model of acute pancreatitis. METHODS: Male Wistar rats (200-400 g) were divided randomly into two groups. Fifteen minutes before surgery, animals received physiological (0.9%) saline (3 mL/kg) (control group) or 45 mg/kg diazoxide (treatment group) via the intravenous route. Acute pancreatitis was induced by injection of 2.5% sodium taurocholate via the biliopancreatic duct...
February 1, 2017: Clinics
https://www.readbyqxmd.com/read/28273236/three-dimensional-structure-and-cytokine-distribution-of-platelet-rich-fibrin
#17
Meng-Yi Bai, Ching-Wei Wang, Jyun-Yi Wang, Ming-Fang Lin, Wing P Chan
OBJECTIVES: Previous reports have revealed that several cytokines (including platelet-derived growth factor-BB, transforming growth factors-β1 and insulin-like growth factor-1) can enhance the rate of bone formation and synthesis of extracellular matrix in orthopaedics or periodontology. This study aimed to determine the concentration of cytokines within platelet-rich fibrin microstructures and investigate whether there are differences in the different portions of platelet-rich fibrin, which has implications for proper clinical use of platelet-rich fibrin gel...
February 1, 2017: Clinics
https://www.readbyqxmd.com/read/28273235/comparisons-of-serum-mirna-expression-profiles-in-patients-with-diabetic-retinopathy-and-type-2-diabetes-mellitus
#18
Jianping Ma, Jufang Wang, Yanfen Liu, Changyi Wang, Donghui Duan, Nanjia Lu, Kaiyue Wang, Lu Zhang, Kaibo Gu, Sihan Chen, Tao Zhang, Dingyun You, Liyuan Han
OBJECTIVES: The aim of this study was to compare the expression levels of serum miRNAs in diabetic retinopathy and type 2 diabetes mellitus. METHODS: Serum miRNA expression profiles from diabetic retinopathy cases (type 2 diabetes mellitus patients with diabetic retinopathy) and type 2 diabetes mellitus controls (type 2 diabetes mellitus patients without diabetic retinopathy) were examined by miRNA-specific microarray analysis. Quantitative real-time polymerase chain reaction was used to validate the significantly differentially expressed serum miRNAs from the microarray analysis of 45 diabetic retinopathy cases and 45 age-, sex-, body mass index- and duration-of-diabetes-matched type 2 diabetes mellitus controls...
February 1, 2017: Clinics
https://www.readbyqxmd.com/read/28273234/non-hdl-cholesterol-is-a-good-predictor-of-the-risk-of-increased-arterial-stiffness-in-postmenopausal-women-in-an-urban-brazilian-population
#19
Rafael de Oliveira Alvim, Carlos Alberto Mourao-Junior, Géssica Lopes Magalhães, Camila Maciel de Oliveira, José Eduardo Krieger, José Geraldo Mill, Alexandre Costa Pereira
OBJECTIVES: Increased arterial stiffness is an important determinant of the risk of cardiovascular disease. Lipid profile impairment, especially hypercholesterolemia, is associated with stiffer blood vessels. Thus, the aim of this study was to determine which of the five circulating lipid components (high-density lipoprotein cholesterol (HDL-C), non-high-density lipoprotein cholesterol (non-HDL-C), low-density lipoprotein cholesterol (LDL), total cholesterol (TC) and triglycerides) is the best predictor of increased arterial stiffness in an urban Brazilian population...
February 1, 2017: Clinics
https://www.readbyqxmd.com/read/28273233/a-brazilian-portuguese-cross-cultural-adaptation-of-the-modified-joa-scale-for-myelopathy
#20
Raphael R Pratali, Justin S Smith, Rodrigo L N Motta, Samuel M Martins, Marcel M Motta, Ricardo D Rocha, Carlos Fernando P S Herrero
OBJECTIVES: To develop a version of the modified Japanese Orthopaedic Association (mJOA) scale that had been translated into Portuguese and cross-culturally adapted for the Brazilian population. METHODS: The well-established process of forward-backward translation was employed along with cross-cultural adaptation. RESULTS: Three bilingual translators (English and native Portuguese) performed the forward translation of the mJOA scale from English to Portuguese based on iterative discussions used to reach a consensus translation...
February 1, 2017: Clinics
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