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Clinics

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https://www.readbyqxmd.com/read/27759853/profibrotic-pathways-and-atrial-cardiomyopathy-in-persistent-atrial-fibrillation
#1
Uğur Canpolat
No abstract text is available yet for this article.
October 1, 2016: Clinics
https://www.readbyqxmd.com/read/27759852/functional-investigation-of-bone-implant-viability-using-radiotracers-in-a-new-model-of-osteonecrosis
#2
Luis Schiper, Bluma Linkowski Faintuch, Roberto José da Silva Badaró, Erica Aparecida de Oliveira, Victor E Arana Chavez, Elisangela Chinen, Joel Faintuch
OBJECTIVES: Conventional imaging methods are excellent for the morphological characterization of the consequences of osteonecrosis; however, only specialized techniques have been considered useful for obtaining functional information. To explore the affinity of radiotracers for severely devascularized bone, a new mouse model of isolated femur implanted in a subcutaneous abdominal pocket was devised. To maintain animal mobility and longevity, the femur was harvested from syngeneic donors...
October 1, 2016: Clinics
https://www.readbyqxmd.com/read/27759851/role-of-the-neutrophil-lymphocyte-ratio-in-the-differential-diagnosis-of-exudative-pleural-effusion
#3
Ulku Aka Akturk, Dilek Ernam, Makbule Ozlem Akbay, Nagihan Durmus Koçak, Erhan Ogur, Ilim Irmak
OBJECTIVES: Pleural effusion is a common diagnostic and clinical problem. The differential diagnosis of pleural effusion may be difficult and may require several procedures, including invasive ones. Certain studies have investigated biochemical parameters to facilitate the diagnosis of exudative pleural effusion; however, it remains a challenging problem in clinical practice. We aimed to investigate the potential role of the neutrophil-lymphocyte ratio, which can be easily obtained by determining the cell count of the pleural fluid, in the differential diagnosis of exudative pleural effusion...
October 1, 2016: Clinics
https://www.readbyqxmd.com/read/27759850/pediatric-minor-head-trauma-do-cranial-ct-scans-change-the-therapeutic-approach
#4
Felipe P Andrade, Roberto Montoro, Renan Oliveira, Gabriela Loures, Luana Flessak, Roberta Gross, Camille Donnabella, Andrea Puchnick, Lisa Suzuki, Rodrigo Regacini
OBJECTIVES: 1) To verify clinical signs correlated with appropriate cranial computed tomography scan indications and changes in the therapeutic approach in pediatric minor head trauma scenarios. 2) To estimate the radiation exposure of computed tomography scans with low dose protocols in the context of trauma and the additional associated risk. METHODS: Investigators reviewed the medical records of all children with minor head trauma, which was defined as a Glasgow coma scale ≥13 at the time of admission to the emergency room, who underwent computed tomography scans during the years of 2013 and 2014...
October 1, 2016: Clinics
https://www.readbyqxmd.com/read/27759849/long-term-results-after-ct-guided-percutaneous-ethanol-ablation-for-the-treatment-of-hyperfunctioning-adrenal-disorders
#5
Nathan Elie Frenk, Fernando Sebastianes, Antonio Marcondes Lerario, Maria Candida Barisson Villares Fragoso, Berenice Bilharinho Mendonca, Marcos Roberto de Menezes
OBJECTIVES: To evaluate the safety and long-term efficacy of computed tomography-guided percutaneous ethanol ablation for benign primary and secondary hyperfunctioning adrenal disorders. METHOD: We retrospectively evaluated the long-term results of nine patients treated with computed tomography-guided percutaneous ethanol ablation: eight subjects who presented with primary adrenal disorders, such as pheochromocytoma, primary macronodular adrenal hyperplasia and aldosterone-producing adenoma, and one subject with Cushing disease refractory to conventional treatment...
October 1, 2016: Clinics
https://www.readbyqxmd.com/read/27759848/the-effect-of-maternal-near-miss-on-adverse-infant-nutritional-outcomes
#6
Dulce M Zanardi, Erly C Moura, Leonor P Santos, Maria C Leal, Jose G Cecatti
OBJECTIVES: To evaluate the association between self-reported maternal near miss and adverse nutritional status in children under one year of age. METHODS: This study is a secondary analysis of a study in which women who took their children under one year of age to the national vaccine campaign were interviewed. The self-reported condition of maternal near miss used the criteria of Intensive Care Unit admission; eclampsia; blood transfusion and hysterectomy; and their potential associations with any type of nutritional disorder in children, including deficits in weight-for-age, deficits in height-for-age, obesity and breastfeeding...
October 1, 2016: Clinics
https://www.readbyqxmd.com/read/27759847/a-phase-iii-randomized-non-inferiority-study-comparing-the-efficacy-and-safety-of-biosimilar-filgrastim-versus-originator-filgrastim-for-chemotherapy-induced-neutropenia-in-breast-cancer-patients
#7
Roberto Hegg, André Mattar, João Nunes de Matos-Neto, José Luiz Pedrini, Sabina Bandeira Aleixo, Roberto Odebrecht Rocha, Renato Peixoto Cramer-Junior, Sylvie van-Eyll-Rocha
OBJECTIVES: To compare the efficacy and safety of two filgrastim formulations for controlling chemotherapy-induced neutropenia and to evaluate the non-inferiority of the test drug relative to the originator. METHODS: This phase III non-inferiority study had a randomized, multicenter, and open-label design. The patients were randomized at a ratio of 1:1 with a follow-up period of 6 weeks for each patient. In both study arms, filgrastim was administered subcutaneously at a daily dose of 5 mg/kg body weight...
October 1, 2016: Clinics
https://www.readbyqxmd.com/read/27759846/velocity-time-integral-for-right-upper-pulmonary-vein-in-vlbw-infants-with-patent-ductus-arteriosus
#8
Gianluca Lista, Silvia Bianchi, Savina Mannarino, Federico Schena, Francesca Castoldi, Mauro Stronati, Fabio Mosca
OBJECTIVE: Early diagnosis of significant patent ductus arteriosus reduces the risk of clinical worsening in very low birth weight infants. Echocardiographic patent ductus arteriosus shunt flow pattern can be used to predict significant patent ductus arteriosus. Pulmonary venous flow, expressed as vein velocity time integral, is correlated to ductus arteriosus closure. The aim of this study is to investigate the relationship between significant reductions in vein velocity time integral and non-significant patent ductus arteriosus in the first week of life...
October 1, 2016: Clinics
https://www.readbyqxmd.com/read/27759845/post-operative-hemimaxillectomy-rehabilitation-using-prostheses-supported-by-zygoma-implants-and-remaining-natural-teeth
#9
Xing Zhou Qu, Ming Yi Wang, Hui Shan Ong, Chen Ping Zhang
OBJECTIVES: This study aimed to evaluate the stability of prostheses supported by zygoma implants and remaining teeth for subjects who had undergone hemi-maxillectomy. METHODS: Ten patients were included in the study. Oral rehabilitation was performed using a temporary prosthesis that was supported by remaining teeth for the first three months. Then, a zygoma implant was placed to provide support for a final prosthesis in addition to the remaining teeth. Each prosthesis was tailor-made according to biomechanical three-dimensional finite element analysis results...
October 1, 2016: Clinics
https://www.readbyqxmd.com/read/27759844/mother-s-freedom-of-choice-and-the-rights-of-an-unborn-child-a-comparison-between-the-views-of-freshmen-and-senior-medical-school-students
#10
Marcelo Shigueo Yosikawa Motoki, Fabio Roberto Cabar, Rossana Pulcineli Vieira Francisco
OBJECTIVES: To compare the views of freshman students with senior students of the Faculty of Medicine- University of São Paulo concerning the respect for the mother's freedom of choice, the need to protect the unborn child, the proportionality between the mother's freedom of choice and the protection of the unborn child, and issues related to legal abortion. To determine whether the medical knowledge acquired throughout the academic years can influence the views of medical students on these issues...
October 1, 2016: Clinics
https://www.readbyqxmd.com/read/27759843/septic-pulmonary-embolism-requiring-critical-care-clinicoradiological-spectrum-causative-pathogens-and-outcomes
#11
Deng-Wei Chou, Shu-Ling Wu, Kuo-Mou Chung, Shu-Chen Han, Bruno Man-Hon Cheung
OBJECTIVES: Septic pulmonary embolism is an uncommon but life-threatening disorder. However, data on patients with septic pulmonary embolism who require critical care have not been well reported. This study elucidated the clinicoradiological spectrum, causative pathogens and outcomes of septic pulmonary embolism in patients requiring critical care. METHODS: The electronic medical records of 20 patients with septic pulmonary embolism who required intensive care unit admission between January 2005 and December 2013 were reviewed...
October 1, 2016: Clinics
https://www.readbyqxmd.com/read/27759842/differential-diagnosis-of-solitary-pulmonary-inflammatory-lesions-and-peripheral-lung-cancers-with-contrast-enhanced-computed-tomography
#12
Zhi-Gang Chu, Bo Sheng, Meng-Qi Liu, Fa-Jin Lv, Qi Li, Yu Ouyang
OBJECTIVES: To clarify differences between solitary pulmonary inflammatory lesions and peripheral lung cancers with contrast-enhanced computed tomography. METHODS: In total, 64 and 132 patients with solitary pulmonary inflammatory masses/nodules and peripheral lung cancers, respectively, were enrolled in this study. Their computed tomographic findings were summarized and compared retrospectively. RESULTS: Compared with the peripheral lung cancers, the inflammatory lesions were located closer to the pleura (p<0...
October 1, 2016: Clinics
https://www.readbyqxmd.com/read/27652838/clinical-features-and-outcomes-of-diffuse-endocapillary-proliferation-henoch-sch%C3%A3-nlein-purpura-nephritis-in-children
#13
Haidong Fu, Jianhua Mao, Yanping Xu, Weizhong Gu, Xiujuan Zhu, Aimin Liu
OBJECTIVE: To investigate the outcomes of childhood diffuse endocapillary proliferation Henoch-Schönlein purpura nephritis (DEP-HSPN) in response to early diagnosis and prompt treatment. METHODS: Eleven cases of DEP-HSPN in children were investigated in comparison to HSPN without diffuse endocapillary proliferation (non-DEP-HSPN). RESULTS: DEP-HSPN had a higher prevalence of nephrotic syndrome but a lower prevalence of hematuria compared to non-DEP-HSPN...
September 2016: Clinics
https://www.readbyqxmd.com/read/27652837/hydrogen-a-potential-safeguard-for-graft-versus-host-disease-and-graft-ischemia-reperfusion-injury
#14
Lijuan Yuan, Jianliang Shen
Post-transplant complications such as graft-versus-host disease and graft ischemia-reperfusion injury are crucial challenges in transplantation. Hydrogen can act as a potential antioxidant, playing a preventive role against post-transplant complications in animal models of multiple organ transplantation. Herein, the authors review the current literature regarding the effects of hydrogen on graft ischemia-reperfusion injury and graft-versus-host disease. Existing data on the effects of hydrogen on ischemia-reperfusion injury related to organ transplantation are specifically reviewed and coupled with further suggestions for future work...
September 2016: Clinics
https://www.readbyqxmd.com/read/27652836/review-of-developments-in-corneal-transplantation-in-the-regions-of-brazil-evaluation-of-corneal-transplants-in-brazil
#15
Hirlana Gomes Almeida, Richard Yudi Hida, Newton Kara
The aim of this study was to identify inequalities in corneal donation and transplantation among the regions of Brazil. A transversal and retrospective study was specifically conducted using data from the Brazilian Transplant Registry collected by the Brazilian Association of Organ Transplantation between January 2002 and December 2014. The collected data were processed using descriptive statistical methods, and p<0.05 was the rate of rejection of the null hypothesis. From 2002 to 2014, there was an increase in the absolute number of corneal transplants, the annual rate of transplants per million people and the percentage of needed transplants performed in each of the five regions of Brazil...
September 2016: Clinics
https://www.readbyqxmd.com/read/27652835/estrogen-deficiency-in-ovariectomized-rats-can-resistance-training-re-establish-angiogenesis-in-visceral-adipose-tissue
#16
Camila do Valle Gomes-Gatto, Fernanda Oliveira Duarte, Uliana Sbeguen Stotzer, Maria Fernanda Cury Rodrigues, Sérgio Eduardo de Andrade Perez, Heloisa Sobreiro Selistre-de-Araujo
OBJECTIVE: The purpose of this study was to investigate the effects of resistance training on angiogenesis markers of visceral adipose tissue in ovariectomized rats. METHOD: Adult Sprague-Dawley female rats were divided into four groups (n=6 per group): sham-sedentary, ovariectomized sedentary, sham-resistance training and ovariectomized resistance training. The rats were allowed to climb a 1.1-m vertical ladder with weights attached to their tails and the weights were progressively increased...
September 2016: Clinics
https://www.readbyqxmd.com/read/27652834/autonomic-and-renal-alterations-in-the-offspring-of-sleep-restricted-mothers-during-late-pregnancy
#17
Joyce R S Raimundo, Cassia T Bergamaschi, Ruy R Campos, Beatriz D Palma, Sergio Tufik, Guiomar N Gomes
OBJECTIVES: Considering that changes in the maternal environment may result in changes in progeny, the aim of this study was to investigate the influence of sleep restriction during the last week of pregnancy on renal function and autonomic responses in male descendants at an adult age. METHODS: After confirmation of pregnancy, female Wistar rats were randomly assigned to either a control or a sleep restriction group. The sleep-restricted rats were subjected to sleep restriction using the multiple platforms method for over 20 hours per day between the 14th and 20th day of pregnancy...
September 2016: Clinics
https://www.readbyqxmd.com/read/27652833/peak-expiratory-flow-mediates-the-relationship-between-handgrip-strength-and-timed-up-and-go-performance-in-elderly-women-but-not-men
#18
Raphael Mendes Ritti-Dias, Gabriel Grizzo Cucato, Fábio Gazelato de Mello Franco, Maysa Seabra Cendoroglo, Fábio Nasri, Maria Luiza Monteiro-Costa, José Antonio Maluf de Carvalho, Luciana Diniz Nagem Janot de Matos
OBJECTIVE: The aim of the present study was to verify if there is sex difference in the associations among handgrip strength, peak expiratory flow (PEF) and timed up and go (TUG) test results. METHODS: The sample included 288 consecutive elderly men (n=93) and women (n=195). Functional capacity was measured using the TUG test, and muscle strength was measured based on handgrip. Moreover, as a measure of current health status, PEF was evaluated. Linear regression procedures were performed to analyze the relationships between handgrip and both PEF and TUG test results, with adjustment for confounders, and to identify the possible mediating role of PEF in the association between handgrip strength and TUG test results...
September 2016: Clinics
https://www.readbyqxmd.com/read/27652832/prenatal-natural-history-of-isolated-fetal-mild-bilateral-pyelectasis
#19
Gustavo de Paula Pereira, Victor Bunduki, Eliane Azeka Hase, Rossana Pulcineli Vieira Francisco, Marcelo Zugaib
OBJECTIVE: To analyze the prenatal outcomes in a cohort of fetuses with mild bilateral pyelectasis and determine whether performing serial ultrasounds is a good follow-up strategy. METHODS: A prospective longitudinal study was conducted on 62 fetuses with mild bilateral pyelectasis. Fetal mild bilateral pyelectasis was considered when the renal pelvis measured (in millimeters) ≥5.0 to 10.0, ≥7.0 to 10.0, and ≥10.0 to 15 at ≤23 weeks 6 days, 24 to 31 weeks 6 days, and ≥32 weeks, respectively, with no uretero-calyceal dilatation...
September 2016: Clinics
https://www.readbyqxmd.com/read/27652831/is-polysomnographic-examination-necessary-for-subjects-with-diaphragm-pathologies
#20
Ozlem Oruc, Sema Sarac, Gulgun Cetintas Afsar, Ozgur Bilgin Topcuoglu, Serda Kanbur, Irfan Yalcinkaya, Fatma Merve Tepetam, Gokhan Kirbas
OBJECTIVES: While respiratory distress is accepted as the only indication for diaphragmatic plication surgery, sleep disorders have been underestimated. In this study, we aimed to detect the sleep disorders that accompany diaphragm pathologies. Specifically, the association of obstructive sleep apnea syndrome with diaphragm eventration and diaphragm paralysis was evaluated. METHODS: This study was performed in Süreyyapasa Chest Diseases and Thoracic Surgery Training and Research Hospital between 2014-2016...
September 2016: Clinics
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