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https://www.readbyqxmd.com/read/28076519/detection-value-of-free-cancer-cells-in-peritoneal-washing-in-gastric-cancer-a-systematic-review-and-meta-analysis
#1
Francisco Tustumi, Wanderley Marques Bernardo, Andre Roncon Dias, Marcus Fernando Kodama Pertille Ramos, Ivan Cecconello, Bruno Zilberstein, Ulysses Ribeiro-Júnior
Intraperitoneal free cancer cells in gastric adenocarcinoma are associated with a poor outcome. However, the true prognostic value of intraperitoneal free cancer cells is still unclear, leading to a lack of consensus in the management of gastric cancer. The aim of the present study is to perform a systematic review and meta-analysis to analyze intraperitoneal free cancer cells-positive patients with regard to tumor oncologic stage, recurrence, grade of cellular differentiation, and survival rates and to analyze the clinical significance of intraperitoneal free cancer cells with regard to prognosis...
December 1, 2016: Clinics
https://www.readbyqxmd.com/read/28076518/serum-klotho-but-not-haplotypes-associate-with-the-post-myocardial-infarction-status-of-older-adults
#2
Roberta S Paula, Vinícius C Souza, Wilcelly Machado-Silva, Bruno Ratier S Almeida, Andersen C Daros, Lucy Gomes, Aparecido P Ferreira, Ciro J Brito, Cláudio Córdova, Clayton F Moraes, Otávio T Nóbrega
OBJECTIVES: The number of deaths from vascular diseases is incredibly high worldwide, and reliable markers for major events are still needed. The current cross-sectional study investigated the association of Klotho haplotypes and Klotho serum levels with classic risk factors and a clinical history of vascular events. METHODS: Clinical, anthropometric, biochemical and nutritional assessments were conducted with 168 older adults, complemented by genotyping (rs9536314 and rs9527025) and the detection of serum Klotho (ELISA)...
December 1, 2016: Clinics
https://www.readbyqxmd.com/read/28076517/standardization-of-the-face-hand-test-in-a-brazilian-multicultural-population-prevalence-of-sensory-extinction-and-implications-for-neurological-diagnosis
#3
Gustavo José Luvizutto, Marcelo Ortolani Fogaroli, Rodolfo Mazeto Theotonio, Hélio Rubens de Carvalho Nunes, Luiz Antônio de Lima Resende, Rodrigo Bazan
OBJECTIVE: The face-hand test is a simple, practical, and rapid test to detect neurological syndromes. However, it has not previously been assessed in a Brazilian sample; therefore, the objective of the present study was to standardize the face-hand test for use in the multi-cultural population of Brazil and identify the sociodemographic factors affecting the results. METHODS: This was a cross sectional study of 150 individuals. The sociodemographic variables that were collected included age, gender, race, body mass index and years of education...
December 1, 2016: Clinics
https://www.readbyqxmd.com/read/28076516/septic-arthritis-of-the-knee-clinical-and-laboratory-comparison-of-groups-with-different-etiologies
#4
Camilo Partezani Helito, Paulo Renan Lima Teixeira, Priscila Rosalba de Oliveira, Vladimir Cordeiro de Carvalho, José Ricardo Pécora, Gilberto Luis Camanho, Marco Kawamura Demange, Ana Lucia Munhoz Lima
OBJECTIVES: To clinically and epidemiologically characterize a population diagnosed with and treated for septic arthritis of the knee, to evaluate the treatment results and to analyze the differences between patients with positive and negative culture results, patients with Gram-positive and Gram-negative bacterial isolates and patients with S. aureus- and non-S. aureus-related infections. METHODS: One hundred and five patients with septic knee arthritis were included in this study...
December 1, 2016: Clinics
https://www.readbyqxmd.com/read/28076515/serum-adipocytokine-profile-and-metabolic-syndrome-in-young-adult-female-dermatomyositis-patients
#5
Marilda Guimarães Silva, Eduardo Ferreira Borba, Suzana Beatriz Veríssimo de Mello, Samuel Katsuyuki Shinjo
OBJECTIVES: To analyse the frequency of metabolic syndrome in young adult female dermatomyositis patients and its possible association with clinical and laboratory dermatomyositis-related features and serum adipocytokines. METHOD: This cross-sectional study included 35 dermatomyositis patients and 48 healthy controls. Metabolic syndrome was defined according to the 2009 Joint Interim Statement. RESULTS: Patient age was comparable in the dermatomyositis and control groups, and the median disease duration was 1...
December 1, 2016: Clinics
https://www.readbyqxmd.com/read/28076514/evaluation-of-embolization-for-periuterine-varices-involving-chronic-pelvic-pain-secondary-to-pelvic-congestion-syndrome
#6
Flavio Meirelles Siqueira, Lucas Moretti Monsignore, Julio Cesar Rosa-E-Silva, Omero Benedicto Poli-Neto, Luis Henrique de Castro-Afonso, Guilherme Seizem Nakiri, Valdair Francisco Muglia, Daniel Giansante Abud
OBJECTIVES: To evaluate the clinical response and success rate after periuterine varices embolization in patients with chronic pelvic pain secondary to pelvic congestion syndrome and to report the safety of endovascular treatment and its rate of complications. METHODS: Retrospective cohort of patients undergoing endovascular treatment of pelvic congestion syndrome in our department from January 2012 to November 2015. Data were analyzed based on patient background, imaging findings, embolized veins, rate of complications, and clinical response as indicated by the visual analog pain scale...
December 1, 2016: Clinics
https://www.readbyqxmd.com/read/28076513/serum-concentration-of-vascular-endothelial-growth-factor-and-depth-of-trophoblastic-invasion-in-ampullary-ectopic-pregnancy
#7
Fábio Roberto Cabar, Décio Roberto Kamio Teshima, Pedro Paulo Pereira, Leila Antonangelo, Regina Schultz, Rossana Pulcineli Francisco
OBJECTIVE: To evaluate the association between the depth of trophoblastic infiltration and serum vascular endothelial growth factorconcentration in patients with an ampullary pregnancy. METHODS: This prospective cross-sectionalstudy involved 34 patients with an ampullary ectopic pregnancy who underwent salpingectomy between 2012 and 2013. Maternal serum vascular endothelial growth factor concentrations were measured using Luminex technology. Trophoblastic invasion was classified histologically as follows: stage I, limited to the tubal mucosa; stage II, reaching the muscle layer; and stage III,involving the full thickness...
December 1, 2016: Clinics
https://www.readbyqxmd.com/read/28076512/mutation-analysis-of-nanos3-in-brazilian-women-with-primary-ovarian-failure
#8
Braian Lucas A Sousa, Mirian Yumie Nishi, Mariza Gerdulo Santos, Vinicius Nahime Brito, Sorahia Domenice, Berenice B Mendonca
OBJECTIVES: Primary ovarian failure is a rare disorder, and approximately 90% of cases are of unknown etiology. The aim of this study was to search for mutations in NANOS3, a gene that was recently related to the etiology of primary ovarian failure, in a group of Brazilian women. METHODS: We screened for NANOS3 DNA variants in 30 consecutive women who were previously diagnosed with primary ovarian failure, of unknown etiology and compared the results with those from 185 women with normal fertility...
December 1, 2016: Clinics
https://www.readbyqxmd.com/read/28076511/passive-acquisition-of-anti-staphylococcus-aureus-antibodies-by-newborns-via-transplacental-transfer-and-breastfeeding-regardless-of-maternal-colonization
#9
Maria Isabel Valdomir Nadaf, Laila Lima, Inês Stranieri, Olga Akiko Takano, Magda Carneiro-Sampaio, Patricia Palmeira
OBJECTIVE: To investigate the transmission of anti-Staphylococcus aureus (Sa) IgG, IgG1 and IgG2 via placental transfer and the transfer of IgA via the colostrum according to maternal Sa carrier status at delivery. METHODS: We evaluated anti-Sa IgG, IgG1 and IgG2 in maternal and cord sera and IgA in colostrum from a case (n=49, Sa+) and a control group (n=98, Sa-). RESULTS: Of the 250 parturients analyzed for this study, 49 were nasally colonized with S...
December 1, 2016: Clinics
https://www.readbyqxmd.com/read/28076510/writing-scientific-articles-like-a-native-english-speaker-concise-writing-for-portuguese-speakers
#10
EDITORIAL
Mariel A Marlow
No abstract text is available yet for this article.
December 1, 2016: Clinics
https://www.readbyqxmd.com/read/27982170/uterine-transplantation-a-systematic-review
#11
Dani Ejzenberg, Luana Regina Baratelli Carelli Mendes, Luciana Bertocco de Paiva Haddad, Edmund Chada Baracat, Luiz Augusto Carneiro D'Albuquerque, Wellington Andraus
Up to 15% of the reproductive population is infertile, and 3 to 5% of these cases are caused by uterine dysfunction. This abnormality generally leads women to consider surrogacy or adoption. Uterine transplantation, although still experimental, may be an option in these cases. This systematic review will outline the recommendations, surgical aspects, immunosuppressive drugs and reproductive aspects related to experimental uterine transplantation in women.
November 1, 2016: Clinics
https://www.readbyqxmd.com/read/27982169/primordial-and-primary-prevention-programs-for-cardiovascular-diseases-from-risk-assessment-through-risk-communication-to-risk-reduction-a-review-of-the-literature
#12
Inês Lancarotte, Moacyr Roberto Nobre
The aim of this study was to identify and reflect on the methods employed by studies focusing on intervention programs for the primordial and primary prevention of cardiovascular diseases. The PubMed, EMBASE, SciVerse Hub-Scopus, and Cochrane Library electronic databases were searched using the terms 'effectiveness AND primary prevention AND risk factors AND cardiovascular diseases' for systematic reviews, meta-analyses, randomized clinical trials, and controlled clinical trials in the English language. A descriptive analysis of the employed strategies, theories, frameworks, applied activities, and measurement of the variables was conducted...
November 1, 2016: Clinics
https://www.readbyqxmd.com/read/27982168/managing-obstructive-sleep-apnoea-in-children-the-role-of-craniofacial-morphology
#13
Maria Fernanda Rabelo Bozzini, Renata Cantisani Di Francesco
Obstructive sleep apnoea syndrome is a type of sleep-disordered breathing that affects 1 to 5% of all children. Pharyngeal and palatine tonsil hypertrophy is the main predisposing factor. Various abnormalities are predisposing factors for obstructive sleep apnoea, such as decreased mandibular and maxillary lengths, skeletal retrusion, increased lower facial height and, consequently, increased total anterior facial height, a larger cranio-cervical angle, small posterior airway space and an inferiorly positioned hyoid bone...
November 1, 2016: Clinics
https://www.readbyqxmd.com/read/27982167/correlation-between-ultrasound-velocity-and-densitometry-in-fresh-and-demineralized-cortical-bone
#14
Alessandro Queiroz de Mesquita, Giuliano Barbieri, Claudio Henrique Barbieri
OBJECTIVE: To compare ultrasound propagation velocity with densitometry in the diaphyseal compact cortical bone of whole sheep metatarsals. METHODS: The transverse ultrasound velocity and bone mineral density of 5-cm-long diaphyseal bone segments were first measured. The bone segments were then divided into four groups of 15 segments each and demineralized in an aqueous 0.5 N hydrochloric acid solution for 6, 12, 24 or 36 hours. All measurements were repeated after demineralization for each time duration and the values measured before and after demineralization were compared...
November 1, 2016: Clinics
https://www.readbyqxmd.com/read/27982166/randomized-trial-of-radiofrequency-ablation-versus-conventional-surgery-for-superficial-venous-insufficiency-if-you-don-t-tell-they-won-t-know
#15
Cynthia de Almeida Mendes, Alexandre de Arruda Martins, Juliana Maria Fukuda, José Ben-Hur Ferraz Parente, Marco Antonio Soares Munia, Alexandre Fioranelli, Marcelo Passos Teivelis, Andrea Yasbek Monteiro Varella, Roberto Augusto Caffaro, Sergio Kuzniec, Nelson Wolosker
OBJECTIVES: This study compared radiofrequency ablation versus conventional surgery in patients who had not undergone previous treatment for bilateral great saphenous vein insufficiency, with each patient serving as his own control. METHOD: This was a randomized controlled trial that included 18 patients and was carried out between November 2013 and May 2015. Each of the lower limbs of each patient was randomly assigned to undergo either radiofrequency ablation or conventional surgery...
November 1, 2016: Clinics
https://www.readbyqxmd.com/read/27982165/lymphocyte-count-as-a-sign-of-immunoparalysis-and-its-correlation-with-nutritional-status-in-pediatric-intensive-care-patients-with-sepsis-a-pilot-study
#16
Talita Freitas Manzoli, Artur Figueiredo Delgado, Eduardo Juan Troster, Werther Brunow de Carvalho, Ana Caroline Barreto Antunes, Desirée Mayara Marques, Patrícia Zamberlan
OBJECTIVES: Developing malnutrition during hospitalization is well recognized worldwide, and children are at a relatively higher risk for malnutrition than adults. Malnutrition can lead to immune dysfunction, which is associated with a higher mortality rate due to sepsis, the most frequent cause of death in pediatric intensive care units (PICUs). The aim of this study was to investigate whether malnourished patients are more likely to have relative or absolute lymphopenia and, consequently, worse prognoses...
November 1, 2016: Clinics
https://www.readbyqxmd.com/read/27982164/immunohistochemical-angiogenic-biomarkers-in-hepatocellular-carcinoma-and-cirrhosis-correlation-with-pathological-features
#17
Osmar Damasceno Ribeiro, Nathalie Henriques Silva Canedo, Vera Lucia Pannain
OBJECTIVE: To investigate immunohistochemical markers of angiogenesis and their association with pathological prognostic features in hepatocellular carcinoma and cirrhotic liver. METHODS: Vascular endothelial growth factor, CD105, and cyclooxygenase-2 were immunohistochemically detected in 52 hepatocellular carcinoma tissue samples and 48 cirrhotic liver tissue samples. Semiquantitative measurements of vascular endothelial growth factor and cyclooxygenase-2 were evaluated considering the degree and intensity of immunostaining based on a 7-point final scoring scale...
November 1, 2016: Clinics
https://www.readbyqxmd.com/read/27982163/mortality-reduction-with-use-of-oral-beta-blockers-in-patients-with-acute-coronary-syndrome
#18
Alexandre de Matos Soeiro, Pedro Gabriel Melo de Barros E Silva, Eduardo Alberto de Castro Roque, Aline Siqueira Bossa, Cindel Nogueira Zullino, Sheila Aparecida Simões, Mariana Yumi Okada, Tatiana de Carvalho Andreucci Torres Leal, Maria Carolina Feres de Almeida Soeiro, Carlos V Serrano, Múcio Tavares Oliveira
OBJECTIVES: Recent studies have revealed a relationship between beta-blocker use and worse prognosis in acute coronary syndrome, mainly due to a higher incidence of cardiogenic shock. However, the relevance of this relationship in the reperfusion era is unknown. The aim of this study was to analyze the outcomes of patients with acute coronary syndrome that started oral beta-blockers within the first 24 hours of hospital admission (group I) compared to patients who did not use oral beta-blockers in this timeframe (group II)...
November 1, 2016: Clinics
https://www.readbyqxmd.com/read/27982162/influence-of-central-obesity-in-estimating-maximal-oxygen-uptake
#19
Christina Grüne de Souza E Silva, Barry A Franklin, Claudio Gil Soares de Araújo
OBJECTIVE: To assess the influence of central obesity on the magnitude of the error of estimate of maximal oxygen uptake in maximal cycling exercise testing. METHOD: A total of 1,715 adults (68% men) between 18-91 years of age underwent cardiopulmonary exercise testing using a progressive protocol to volitional fatigue. Subjects were stratified by central obesity into three quartile ranges: Q1, Q2-3 and Q4. Maximal oxygen uptake [mL.(kg.min)-1] was estimated by the attained maximal workload and body weight using gender- and population-specific equations...
November 1, 2016: Clinics
https://www.readbyqxmd.com/read/27982161/first-latin-uterine-transplantation-we-can-do-it
#20
EDITORIAL
José Maria Soares, Dani Ejzenberg, Wellington Andraus, Luiz Augusto Carneiro D'Albuquerque, Edmund Chada Baracat
No abstract text is available yet for this article.
November 1, 2016: Clinics
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