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Psychiatry Investigation

Geumsook Shim, Bumseok Jeong
OBJECTIVE: The present study aimed to identify risk factors for future SI and to predict individual-level risk for future or persistent SI among college students. METHODS: Mental health check-up data collected over 3 years were retrospectively analyzed. Students were categorized as suicidal ideators and non-ideators at baseline. Logistic regression analyses were performed separately for each group, and the predicted probability for each student was calculated. RESULTS: Students likely to exhibit future SI had higher levels of mental health problems, including depression and anxiety, and significant risk factors for future SI included depression, current SI, social phobia, alcohol problems, being female, low self-esteem, and number of close relationships and concerns...
November 2, 2018: Psychiatry Investigation
Shieun Yu, Jungeun Jang, Jin-Won Noh, Young Dae Kwon, Hyunchun Park, Jong-Min Woo
OBJECTIVE: We investigated how mental health awareness among North Korean refugees transformed depending on temporal-spatial context changes. METHODS: In 2013, we conducted interviews with 10 refugees (eight women) who had been in South Korea for over a year and performed a qualitative analysis of the change in mental health awareness in the differences between living in North Korea, escape (a related period of forced sojourn in a third country), and settlement in South Korea...
November 2, 2018: Psychiatry Investigation
Hee-Ju Kang, Kyung-Yeol Bae, Sung-Wan Kim, Il-Seon Shin, Young Joon Hong, Youngkeun Ahn, Myung Ho Jeong, Jin-Sang Yoon, Jae-Min Kim
OBJECTIVE: Patients with acute coronary syndrome (ACS) are at an increased risk of suicide. It is well known that epigenetic mechanisms may explain the pathophysiology of suicidal behavior including suicidal ideation (SI), but no study has explored these mechanisms in ACS populations. METHODS: In total, 969 patients were initially recruited within 2 weeks of the acute coronary event and, 711 patients were successfully followed up 1 year after ACS. SI was evaluated using the relevant items on the Montgomery-Åsberg Depression Rating Scale and covariates potentially affecting SI were estimated...
November 2, 2018: Psychiatry Investigation
Can Ilgın, Ahmet Topuzoğlu
The analysis of extracellular vesicles has been accelerated because of the technological advancements in omics methods in recent decades. Extracellular vesicles provide multifaceted information regarding the functional status of the cells. This information would be critical in case of central nervous system cells, which are confined in a relatively sealed biological compartment. This obstacle is more dramatic in psychiatric disorders since their diagnosis primarily depend on the symptoms and signs of the patients...
November 2, 2018: Psychiatry Investigation
Dandan Wang, Shaojia Lu, Weijia Gao, Zhaoguo Wei, Jinfeng Duan, Shaohua Hu, Manli Huang, Yi Xu, Lingjiang Li
OBJECTIVE: The aims of the present study were to explore the occurrence of childhood trauma and importantly to determine the impacts of childhood trauma on psychosocial features in a Chinese sample of young adults. METHODS: A survey was carried out in a group of 555 university students by using Childhood Trauma Questionnaire (CTQ), Self-rating Depression Scale (SDS), Self-rating Anxiety Scale (SAS), Dysfunctional Attitudes Questionnaire (DAS), Eysenck Personality Questionnaire (EPQ), and Social Support Rating Scale (SSRS)...
November 2, 2018: Psychiatry Investigation
Won Joon Lee, Soo-Hee Choi, Jung Eun Shin, Chang Young Oh, Na Hyun Ha, Ul Soon Lee, Yoonji Irene Lee, Yoobin Choi, Saerom Lee, Joon Hwan Jang, Yun-Chul Hong, Do-Hyung Kang
OBJECTIVE: We developed easily accessible imagery-based treatment program for patients with post-traumatic stress disorder (PTSD) related to workplace accidents and investigated the effects of the program on various PTSD related symptoms. METHODS: The program was based on an online platform and consisted of eight 15-min sessions that included script-guided imagery and supportive music. Thirty-five patients with workplace-related PTSD participated in this program 4 days per week for 4 weeks...
November 2, 2018: Psychiatry Investigation
Hyeon-Ah Lee, Ji-Sun Kim, Yeon-Jung Lee, Nam-Hun Heo, Se-Hoon Shim, Young-Joon Kwon
OBJECTIVE: The aim of this study was to evaluate differences in psychopathology between offspring of parents with bipolar I disorder (BP-I) and those with bipolar II disorder (BP-II). METHODS: The sample included 201 offspring between 6 and 17 years of age who had at least one parent with BP-I or BP-II. The offspring were diagnostically evaluated using the Korean Kiddie-Schedule for Affective Disorders and Schizophrenia-Present and Lifetime Version. Psychopathology and Clinical characteristics were evaluated, including lifetime DSM-5 diagnoses, depression, and childhood trauma...
October 26, 2018: Psychiatry Investigation
Seon-Cheol Park, Yong-Ku Kim
To conceptualize a novel bio-psychosocial-behavioral treatment model of panic disorder (PD), it is necessary to completely integrate behavioral, psychophysiological, neurobiological, and genetic data. Molecular genetic research on PD is specifically focused on neurotransmitters, including serotonin, neuropeptides, glucocorticoids, and neurotrophins. Although pharmacological interventions for PD are currently available, the need for more effective, faster-acting, and more tolerable pharmacological interventions is unmet...
October 11, 2018: Psychiatry Investigation
Seunghyong Ryu, Hyeongrae Lee, Dong-Kyun Lee, Kyeongwoo Park
OBJECTIVE: In this study, we aimed to develop a model predicting individuals with suicide ideation within a general population using a machine learning algorithm. METHODS: Among 35,116 individuals aged over 19 years from the Korea National Health & Nutrition Examination Survey, we selected 11,628 individuals via random down-sampling. This included 5,814 suicide ideators and the same number of non-suicide ideators. We randomly assigned the subjects to a training set (n=10,466) and a test set (n=1,162)...
October 11, 2018: Psychiatry Investigation
Kang-Seob Oh, Eun-Jin Kim, Ju-Won Ha, Hee-Yeon Woo, Min-Jung Kwon, Dong-Won Shin, Young-Chul Shin, Se-Won Lim
OBJECTIVE: The pathophysiology of social anxiety disorder (SAD) is not yet well understood, but previous research has suggested that oxytocin is associated with social behavior and may play a role in human anxiety states and anxiety-related traits. The aim of this study was to investigate the possible relationship between social anxiety symptoms and plasma oxytocin levels. METHODS: Twenty-three male patients with SAD and 28 healthy male controls participated in this study...
October 11, 2018: Psychiatry Investigation
Fiammetta Cosci, Giovanni Mansueto
Objective: Classifying mental disorders on the basis of objective makers might clarify their aetiology, help in making the diagnosis, identify "at risk" individuals, determine the severity of mental illness, and predict the course of the disorder. This study aims to review biological and clinical markers of panic disorder (PD). Methods: A computerized search was carried out in PubMed and Science Direct using the key words: "marker/biomarker/clinical marker/neurobiology/staging" combined using Boolean AND operator with "panic...
September 5, 2018: Psychiatry Investigation
Chien-Han Lai
The core concept for pathophysiology in panic disorder (PD) is the fear network model (FNM). The alterations in FNM might be linked with disturbances in the autonomic nervous system (ANS), which is a common phenomenon in PD. The traditional FNM included the frontal and limbic regions, which were dysregulated in the feedback mechanism for cognitive control of frontal lobe over the primitive response of limbic system. The exaggerated responses of limbic system are also associated with dysregulation in the neurotransmitter system...
September 5, 2018: Psychiatry Investigation
Yong Chon Park, Shu-Yu Yang, Mian-Yoon Chong, Shigenobu Kanba, Norman Sartorius, Naotaka Shinfuku, Chay-Hoon Tan, Seon-Cheol Park
The REAP-AP study recruited 3,746 patients with schizophrenia, in March and April 2016, from 71 centers in 15 Asian countries/territories namely Bangladesh, China, Hong Kong, India, Indonesia, Japan, Korea, Malaysia, Myanmar, Pakistan, Singapore, Sri Lanka, Taiwan, Thailand and Vietnam. Our findings reveal a trend according to which high dose antipsychotic prescription is more prevalent in Eastern Asia (especially, Japan and Korea) than in other regions of Asia. This historical factor may be associated with our finding of an Eastern Asian preponderance of high dose antipsychotic prescription...
October 2018: Psychiatry Investigation
Hyun Kook Lim
No abstract text is available yet for this article.
October 2018: Psychiatry Investigation
Hyunjeong Kim, Jin Young Park, Kwanguk Kenny Kim
OBJECTIVE: A radial arm maze (RAM) is an essential tool for assessing spatial learning and memory. Although this tool is widely used to study deficits in spatial memory in animal models, it has several restrictions that prevent its adaptation to human research and training. Therefore, we developed a head-mounted-display RAM (HMD-RAM) program for humans and verified its validity by comparing it to the results obtained by previous RAM studies. We also compared the HMD and a flat monitor as experimental devices...
October 2018: Psychiatry Investigation
Kwok Kei Mak, Jaeseung Jeong, Hye-Kyung Lee, Kounseok Lee
OBJECTIVE: This study examined the mediating role of internet addiction in the association between psychological resilience and depressive symptoms. METHODS: 837 Korean university students completed a survey with items of demographic information, Connor-Davidson Resilience Scale (CD-RISC), Internet Addiction Test (IAT), and Patient Health Questionnaire (PHQ-9) in 2015. The complex associations among psychological resilience, internet addiction, and depressive symptoms were delineated using structural equation models...
October 2018: Psychiatry Investigation
Lale Gönenir Erbay, İsmail Reyhani, Süheyla Ünal, Cemal Özcan, Tuba Özgöçer, Cihat Uçar, Sedat Yıldız
OBJECTIVE: Little is known about the effects of psychodrama group therapy on the level of stress, anxiety and depression of the group members, and the biological markers of stress. The aim of this study test cortisol level as a biological reflection of some mental characteristics gained by the psychodrama method in coping with stress. METHODS: Depressive patients aged between 18 and 65 years, who diagnosed with depression according to DSM-5, without psychiatric comorbidity, who do not use drugs and were available for psychodrama were enrolled into the study...
October 2018: Psychiatry Investigation
Kyu-Sic Hwang, Seung-Ho Jang, Hye-Jin Lee, Sang-Yeol Lee
OBJECTIVE: Health anxiety can be defined by concern about health in the absence of a pathology. The Health Anxiety Questionnaire (HAQ) based on the cognitive-behavioral model can be useful for evaluating the severity and the structure of health anxiety. This study aims to verify the reliability and validity of Korean version of HAQ (K-HAQ). METHODS: For reliability, test-retest reliability and internal consistency were analyzed. For construct validity, exploratory factor analysis (EFA) and confirmatory factor analysis (CFA) were conducted...
October 2018: Psychiatry Investigation
Erkan Baysak, Fatma Duygu Kaya Yertutanol, Ilker Dalgar, Selçuk Candansayar
OBJECTIVE: Prospective data of risky online gamers in Turkey is missing. Therefore, we aimed to investigate the change in gaming behaviors and addiction rates of Travian players within two years to search diagnostic stability of internet gaming disorder and some psychosocial risk factors. METHODS: 110 responders completed the whole questionnaire package including 21-item Game Addiction Scale (GAS), Satisfaction with Life Scale (SLS), Rosenberg Self-Esteem Scale (RSES), and Multi-dimensional Scale of Perceived Social Support (MSPSS)...
October 2018: Psychiatry Investigation
Ji Hyun Baek, Jeong Hyun Kim, Sohee Oh, Ju Young Kim, Soyoung Baik
OBJECTIVE: We developed a fully automated smartphone-based stress management application and explored its usability, potential feasibility, and preliminary efficacy for stress management in Korean employees. METHODS: Healthy employees working in large public enterprises were enrolled. Participants used our automated stress management application for four weeks. With the application, they monitored their stress level and life style factors. Personalized stress management techniques, including psychoeducation and cognitive behavioral technique, were also provided based on their stress level and lifestyle pattern...
October 2018: Psychiatry Investigation
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