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Psychiatry Investigation

Zhongde Pan, Chao Gui, Jing Zhang, Jie Zhu, Donghong Cui
Objective: This study was aimed to compare the accuracy of Support Vector Machine (SVM) and Gaussian Mixture Model (GMM) in the detection of manic state of bipolar disorders (BD) of single patients and multiple patients. Methods: 21 hospitalized BD patients (14 females, average age 34.5±15.3) were recruited after admission. Spontaneous speech was collected through a preloaded smartphone. Firstly, speech features [pitch, formants, mel-frequency cepstrum coefficients (MFCC), linear prediction cepstral coefficient (LPCC), gamma-tone frequency cepstral coefficients (GFCC) etc...
July 4, 2018: Psychiatry Investigation
Sook-Hyun Lee, Gyurin Kim, Chul-Eung Kim, Seunghyong Ryu
Objective: This study aimed to investigate clinical factors contributing to the low physical activity (PA) of patients with chronic schizophrenia. Methods: PA was measured in 50 outpatients with chronic schizophrenia using the International Physical Activity Questionnaire Short Form (IPAQ-SF). Psychopathology, psychosocial functioning, and extrapyramidal symptoms were assessed using the 18 item-Brief Psychiatric Rating Scale (BPRS-18), Global Assessment of Functioning (GAF), and Drug-Induced Extrapyramidal Symptom Scale (DIEPSS), respectively...
July 4, 2018: Psychiatry Investigation
Jae Hyuk Shin, Kyungun Jhung, Jae Seok Heo, Suk Kyoon An, Jin Young Park
Objective: We utilized a spectral and network analysis technique with an integrated support vector classification algorithm for the automated detection of cognitive capacity using resting state electroencephalogram (EEG) signals. Methods: An eyes-closed resting EEG was recorded in 158 older subjects, and spectral EEG parameters in seven frequency bands, as well as functional brain network parameters were, calculated. In the feature extraction stage, the statistical power of the spectral and network parameters was calculated for the low-, moderate-, and high-performance groups...
July 4, 2018: Psychiatry Investigation
Taehyun Kim, Hyeon Jeong, Ji Won Han, Kyung Phil Kwak, Bong-Jo Kim, Shin-Kyeom Kim, Jeong Lan Kim, Tae Hui Kim, Seung-Ho Ryu, Seok Woo Moon, Jae Young Park, Joon Hyuk Park, Jae Nam Bae, Jong Chul Youn, Dong Young Lee, Dong Woo Lee, Seok Bum Lee, Jung Jae Lee, Jin Hyeong Jhoo, Jungwon Lee, Ki Woong Kim
Objective: We investigated the prevalence and risk factors of physically abusive behaviors (PhAB) and psychologically abusive behaviors (PsAB) towards people with dementia (PWD) in family caregivers, and compared their prevalences between East Asian and Western countries. Methods: We estimated the prevalence and risk factors of PhAB and PsAB in 467 Korean pairs of community-dwelling PWD and their primary family caregivers. We evaluated abusive behaviors using the Modified Conflict Tactics Scale...
July 4, 2018: Psychiatry Investigation
Sun-Jin Jo, Kyoung-Sae Na, Joo Eon Park, Myung-Soo Lee
Objective: The purpose of this study was to determine the key components of Korean disaster psychiatric assistant teams (K-DPATs), to set up new mental health service providing system for the disaster victims. Methods: We conducted an analytic hierarchy process (AHP) involving disaster mental health experts, using a pairwise comparison questionnaire to compare the relative importance of the key components of the Korean disaster mental health response system. In total, 41 experts completed the first online survey; of these, 36 completed the second survey...
June 28, 2018: Psychiatry Investigation
Se Hyun Kim, Hong Geun Park, Seong Hoon Jeong, Ung Gu Kang, Yong Min Ahn, Yong Sik Kim
Objective: Electroconvulsive therapy (ECT) is the most effective treatment for mood disorders. Accumulating evidence has suggested the important role of circadian genes in mood disorders. However, the effects of ECT on circadian genes have not been systemically investigated. Methods: We examined the expression and daily oscillation of major circadian genes in the rat frontal cortex after electroconvulsive seizure (ECS). Results: Firstly, mRNA and protein level were investigated at 24 hr after single ECS (E1X) and repeated ECS treatements for 10 days (E10X), which showed more remarkable changes after E10X than E1X...
June 28, 2018: Psychiatry Investigation
Ha-Young Ko, Won-Hye Lee, Eun-Kyung Won, Ji Jeong Ban, Da Eun Jung, Yeni Kim
Objective: This study was conducted to investigate the reliability and validity of the Korean version of Autism-Spectrum Quotient (AQ). Methods: 20 participants with high-functioning autism (HFA) and 99 normal participants were recruited. All participants were completed the AQ and Empathy Quotient (EQ), and parents of the HFA group completed the parent-report AQ. For testing the reliability, we examined Cronbach's alpha, performed item analysis, and compared self versus parent report score of HFA participants...
June 28, 2018: Psychiatry Investigation
Masaki Shiraishi, Takao Ishii, Yoshiyasu Kigawa, Masaya Tayama, Keisuke Inoue, Kenji Narita, Masaru Tateno, Chiaki Kawanishi
Many patients with mental disorders visit emergency departments (EDs). However, the majority of these patients do not receive psychiatric assessment. In the present study, we investigated the detailed proportion of patients with mental disorders visiting an urban ED in the largest northern city in Japan. A retrospective chart review study was performed at a University Hospital from January 2012 to December 2015. The reasons for psychiatric consultations made by ED staff, and the primary psychiatric diagnoses were investigated...
June 28, 2018: Psychiatry Investigation
Young-Min Park, Bun-Hee Lee
Objective: Some clinical studies have found alterations in the levels of serum brain-derived neurotrophic factor (BDNF) and glial cell line-derived neurotrophic factor (GDNF) after applying antidepressant treatment in patients with major depressive disorder (MDD). We evaluated the serum BDNF and GDNF levels before and after 12 weeks of antidepressant treatment in MDD outpatients. Methods: Serum BDNF and GDNF levels were measured in 23 female MDD outpatients at baseline and after 12 weeks of treatment...
June 28, 2018: Psychiatry Investigation
Che-Sheng Chu, Dian-Jeng Li, Chin-Liang Chu, Chih-Ching Wu, Ti Lu
Objective: Schizophrenia (SZ) has been associated with the inflammatory-related and immunological pathogenesis. This study investigates the aberration of cytokines in patients with SZ. Methods: Thirty patients with SZ without antipsychotic treatment for at least two weeks participated. We measured the serum levels of fourteen cytokines at hospital admission and after 8-week antipsychotic treatment. Severity was measured by expanded version of 24-items brief psychiatric rating scale (BPRS-E)...
June 15, 2018: Psychiatry Investigation
Bum-Sung Choi, Ji Sun Kim, Dong-Woo Lee, Jong-Woo Paik, Boung Chul Lee, Jung Won Lee, Ho-Sung Lee, Hwa-Young Lee
Objective: We examined associations between emotional exhaustion and selected sociodemographic and psychological factors among nurses in inpatient and outpatient nursing units at a university hospital in South Korea. Methods: The participants were 386 nurses who completed the Maslach Burnout Inventory, a measure of emotional exhaustion. Psychological characteristics were evaluated, including hardiness, self-esteem, experience of trauma, resilience, perceived stress, and social support...
June 15, 2018: Psychiatry Investigation
Na Young Shin, Hye Yoon Park, Wi Hoon Jung, Jun Soo Kwon
Objective: Research has shown that intranasal oxytocin affects social cognition and behavior; however, its effects vary based on social context, individual characteristics and dose. The present study aimed to determine effective dose of oxytocin spray on emotion recognition in healthy Korean males. Methods: The study followed a randomized, double-blind, placebo-controlled design. Thirty-seven Korean males underwent two experimental sessions, with one week in between...
June 15, 2018: Psychiatry Investigation
In Cheol Hwang, Kyoung-Sae Na, Yu Jin Lee, Seung-Gul Kang
Objective: This study investigated the proposed association between restless legs syndrome (RLS) and the prevalence of hypertension. Methods: A meta-analysis was conducted based on searches of the PUBMED, EMBASE, Cochrane Library, and Korean electronic databases. Cohort and cross-sectional studies reporting the incidence of hypertension in individuals with RLS were included. Dichotomous data were pooled to obtain an odds ratio (OR) and 95% confidence interval (CI) for the prevalence of hypertension in individuals with RLS...
June 15, 2018: Psychiatry Investigation
Eun-Jeong Kim, Yong-Ku Kim
Objective: Brain-derived neurotrophic factor (BDNF) has possible neurobiologic impact on etiology of schizophrenia. We hypothesized that the specific allele or the genotype such as two single nucleotide polymorphisms (SNPs) , 196G/A (rs6265), 11757G/C(rs16917204) is associated with schizophrenia or its clinical features. Methods: 241 normal controls and 157 schizophrenia patients are included. The differences in allele or genotype distribution for the patients and normal controls were analyzed...
June 15, 2018: Psychiatry Investigation
Xiaofei Kang, Yueyan Fang, Sihan Li, Yadong Liu, Di Zhao, Xiujuan Feng, Yaqi Wang, Ping Li
Objective: Ambulance personnel who witness trauma experienced by patients have been reported to experience positive changes, known as vicarious posttraumatic growth (VPTG). We examined VPTG and its relationship with social support and resilience among ambulance personnel. Methods: The sample (n=227) was recruited from six emergency centers in China. The measures included the Posttraumatic Growth Inventory (PTGI), the Social Support Rating Scale (SSRS), and the 10-item Connor-Davidson Resilience Scale (CD-RISC-10)...
April 27, 2018: Psychiatry Investigation
Kyung Mee Park, Tae Ho Kim, Woo Jung Kim, Suk Kyoon An, Kee Namkoong, Eun Lee
Objective: This study determined whether cognitive behavioral therapy for insomnia (CBT-i) decreased the need for sleep medications and produced better treatment outcomes than pharmacotherapy alone. Methods: We reviewed data from patients with insomnia in the outpatient clinic of a general hospital between 2009 and 2015. We compared 41 patients who received five sessions of CBT-i with 100 age- and sex-matched patients who received pharmacotherapy only. We evaluated the change in prescription for sleep (i...
April 27, 2018: Psychiatry Investigation
Minah Kim, Yoo Bin Kwak, Tae Young Lee, Jun Soo Kwon
Objective: Transcranial direct current stimulation (tDCS) is a non-invasive neuromodulation technique increasingly used to relieve symptoms of psychiatric disorders. Electrophysiologic markers, such as electroencephalography (EEG) and event-related potentials (ERP), have high temporal resolution sensitive to detect plastic changes of the brain associated with symptomatic improvement following tDCS application. Methods: We performed systematic review to identify electrophysiological markers that reflect tDCS effects on plastic brain changes in psychiatric disorders...
April 27, 2018: Psychiatry Investigation
Seok Woo Moon, Boram Lee, Young Chil Choi
Objective: The aim of this study was to examine the change in the hippocampal volume and shape in early-onset mild cognitive impairment (EO-MCI) associated with the APOE ε4 carrier state. Methods: This study had 50 subjects aged 55-63 years, all of whom were diagnosed with MCI at baseline via the Korean version of the Consortium to Establish a Registry for Alzheimer's Disease Assessment Packet. The EO-MCI patients were divided into the MCI continued (MCIcont) and Alzheimer's disease (AD) converted (ADconv) groups 2 years later...
April 27, 2018: Psychiatry Investigation
Kukju Kweon, Je Sik Yoon, Kee Jeong Park, Seon-Ok Kim, Jin-Ho Choi, Hyo-Won Kim
Objective: We aimed to investigate the long-term effects of atomoxetine on growth in Korean children and adolescents with attention-deficit/hyperactivity disorder (ADHD). Methods: The medical records of 82 subjects (mean age, 9.0±2.0 years; 64 boys) with ADHD treated with atomoxetine for at least 1 year at the Department of Psychiatry at Asan Medical Center were retrospectively reviewed. Height and weight data were prospectively obtained and retrospectively gathered and converted to age- and gender-corrected z scores using norms from Korean youths...
June 2018: Psychiatry Investigation
Heejun Shin, Ho Jung Kim, Shingyeom Kim, Sunjin Choi, Heeju Oh, Bora Lee
Objective: The purpose of this study was to analyze the characteristics and factors of voluntary discharged patients after suicide attempt and analyze the effectiveness of follow-up measures. Methods: Total 504 adult patients aged 14 years and over, who visited a local emergency medical center from September 1, 2013 to December 31, 2015 were enrolled and retrospectively reviewed. We analyzed the relationship with voluntary discharge group (VDG) among basic characteristics, suicidal attempt variables, outcome variables related to suicide attempts, and treatment related variables comparing with normal discharge group (NDG)...
June 2018: Psychiatry Investigation
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