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Psychiatry Investigation

Erna Laere, Shiau Foon Tee, Pek Yee Tang
OBJECTIVE: The present meta-analysis aimed to analyze the cognitive performance of schizophrenia patients measured by Trail Making Tests (TMT) and the contribution of socio-demographic factors to cognitive impairments. METHODS: PubMed and PsycARTICLES databases were searched for the studies published between January 1985 and November 2017. Data were drawn from 19 studies encompassing 1095 patients and 324 controls. The effect size and heterogeneity were assessed with Comprehensive Meta-Analysis version 2 using random-effect model...
September 19, 2018: Psychiatry Investigation
Fang Shen, Wan-Li Huang, Bao-Ping Xing, Xiang Fang, Mei Feng, Chun-Ming Jiang
Objective: Recent studies have indicated the possibility that genistein may improve depression via regulating the expression of miR221/222. This study is to explore whether genistein could improve depression by altering miR-221/222 levels and investigate the possible mechanisms involved in the improvement effect of genistein. Methods: The animal model of depression was established through unpredictable chronic mild stress. Nest building test and splash test were adapted to evaluate the effects of genistein on depressive symptoms in mice...
September 13, 2018: Psychiatry Investigation
Jiyoung Lyu, Hae-Young Kim
Objective: Sensory impairments, such as vision and hearing impairments, increase with age, and studies have shown that self-reported vision and hearing impairments are associated with adverse mental health outcomes in later life. Although gender differences may exist in the associations between sensory impairments and geriatric mental health outcomes, little research has been done examining gender differences in the above associations. Therefore, the purpose of this study was to investigate the relationship between self-reported sensory impairments and geriatric mental health outcomes with the aim of determining whether any association differs by gender...
September 13, 2018: Psychiatry Investigation
Miho Ota, Junko Matsuo, Noriko Sato, Toshiya Teraishi, Hiroaki Hori, Kotaro Hattori, Yoko Kamio, Norihide Maikusa, Hiroshi Matsuda, Hiroshi Kunugi
Objective: Autistic spectrum traits are postulated to lie on a continuum that extends between individuals with autism and individuals with typical development. The present study was carried out to investigate functional and network abnormalities associated with autistic spectrum trait in healthy male subjects. Methods: Subjects were 41 healthy male subjects who underwent the social responsiveness scale-adult (SRS-A) and magnetic resonance imaging. Results: There was significant positive correlation between the total score of SRS-A and the regional cerebral blood flow (CBF) in posterior cingulate cortex (PCC)...
September 13, 2018: Psychiatry Investigation
Fiammetta Cosci, Giovanni Mansueto
Objective: Classifying mental disorders on the basis of objective makers might clarify their aetiology, help in making the diagnosis, identify "at risk" individuals, determine the severity of mental illness, and predict the course of the disorder. This study aims to review biological and clinical markers of panic disorder (PD). Methods: A computerized search was carried out in PubMed and Science Direct using the key words: "marker/biomarker/clinical marker/neurobiology/staging" combined using Boolean AND operator with "panic...
September 5, 2018: Psychiatry Investigation
Chien-Han Lai
The core concept for pathophysiology in panic disorder (PD) is the fear network model (FNM). The alterations in FNM might be linked with disturbances in the autonomic nervous system (ANS), which is a common phenomenon in PD. The traditional FNM included the frontal and limbic regions, which were dysregulated in the feedback mechanism for cognitive control of frontal lobe over the primitive response of limbic system. The exaggerated responses of limbic system are also associated with dysregulation in the neurotransmitter system...
September 5, 2018: Psychiatry Investigation
Jennifer Apolinário-Hagen
Background: Internet-delivered psychological treatments have been suggested as a chance to expand the access to professional help. However, little is known about the usefulness of different support formats and approaches of digital treatments for panic disorder among clinicians. Objective: This narrative review aimed to explore the recent evidence base on the efficacy and acceptability of different internet-delivered treatments for adults with panic disorder. Methods: A systematic search in electronic databases (Pubmed/Medline, PSYNDEX) and a hand search were performed to identify articles on randomized controlled trials published within the past five years (2012/12/10-2017/12/12) in English peer-reviewed journals...
August 20, 2018: Psychiatry Investigation
Jieun Yang, Eun-Cheol Park, Sang Ah Lee, Joo Eun Lee, Dong-Woo Choi, Wonjeong Chae, Sung-In Jang
OBJECTIVE: South Korea has an increasing aging population; thus, the management of depressive symptoms in elderly individuals is important. In this population, fewer social contacts might be a risk factor for depressive symptoms. We examined associations between the frequency of social contacts and depressive symptoms among elderly Koreans and factors associated with these symptoms. METHODS: Data from 62,845 individuals over 65 years of age enrolled in the 2015 Community Health Survey were used in this study...
September 2018: Psychiatry Investigation
Hong Jun Jeon, Jee Hyun Ha, Seung-Ho Ryu, Jaehak Yu, Doo-Heum Park
OBJECTIVE: Previous findings suggest that hand movement laterality is reversed during sleep. The present study aimed to verify this phenomenon and evaluate whether the extent of reversal is correlated with the severity of sleep apnea. METHODS: A total of 184 participants (mean age: 44.5±13.0 years; 81.5% males) wore actigraphs on both hands during sleep, and nocturnal polysomnography was simultaneously performed. RESULTS: Actigraphic indices of hand movement were significantly higher for the left hand than those for the right hand (p<0...
September 2018: Psychiatry Investigation
Sung-Doo Won, Changwoo Han
OBJECTIVE: The aim of this study was to examine the reliability and validity of the Korean version of the Impaired Control Scale (K-ICS), a scale to screen patients with alcohol use disorder. METHODS: Participants were 173 inpatients with alcohol use disorder (AUD), and 174 normal controls (NC). Both AUD and NC groups completed the K-ICS as well as the Alcohol Dependence Scale (ADS), the Alcohol Abstinence Self-Efficacy Scale (AASES), the Brief Self-Control Scale (BSCS), and the Hospital Anxiety and Depression Scale (HAD)...
September 2018: Psychiatry Investigation
Eun Hyun Seo, Hoowon Kim, Kyu Yeong Choi, Kun Ho Lee, Il Han Choo
OBJECTIVE: Little is known about the natural course of pre-mild cognitive impairment (pre-MCI) and predictors to MCI. We followedup individuals with pre-MCI and cognitively normal (CN) elders to identify neuropsychological predictors for rapid conversion to MCI. METHODS: Seventy-seven individuals with pre-MCI and 180 CN elders were recruited from the pool of individuals registered at the National Research Center for Dementia in Gwangju, Korea. We followed-up with them after a mean of 14±2...
September 2018: Psychiatry Investigation
Eunchong Seo, Minji Bang, Eun Lee, Suk Kyoon An
OBJECTIVE: This study aimed to investigate whether aberrant tendency of noncurrent emotion was present in individuals at ultra-high risk (UHR) for psychosis and to explore its associations with various clinical profiles. METHODS: Fifty-seven individuals at UHR and 49 normal controls were enrolled. The tendency of experiencing noncurrent emotion was assessed using various noncurrent emotional self-reported formats, including trait [Neuroticism and Extraversion of the Eysenck Personality Questionnaire], hypothetical (Chapman's Revised Physical and Social Anhedonia Scales), and retrospective [AnhedoniaAsociality Subscale of the Scale for the Assessment of Negative Symptoms (SANS)] measures...
September 2018: Psychiatry Investigation
Leman İnanç, Merih Altıntaş
OBJECTIVE: The aim of this study is to investigate whether insight and mentalizing abilities are related to the severity of Obsessive Compulsive Disorder (OCD) in treatment resistant OCD. We look at the association between treatment resistance, insight, and mentalizing ability. METHODS: The study was conducted with 71 OCD patients; 30 of them met the criteria for treatment resistant OCD, whereas the other 41 (57.7%) were labeled as responder group. All patients were assessed with the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS), Reading the Mind in the Eyes Test (RMET), Brown Assessment of Beliefs Scale (BABS), Mini International Neuropsychiatric Interview, Beck Depression Inventory, and Beck Anxiety Inventory...
September 2018: Psychiatry Investigation
Hye Yoon Park, Minji Bang, Kyung Ran Kim, Eun Lee, Suk Kyoon An
Objective: Biased attribution styles of assigning hostile intention to innocent others and placing the blame were found in schizophrenia. Attribution styles in individuals at ultra-high risk (UHR) for psychosis, however, have been less studied especially for its association with various psychological factors. We investigated whether UHR individuals show increased hostility perception and blaming bias and explored the associations of these biased styles of attribution with the factor structure of multifaceted self-related psychological variables and neurocognitive performances...
August 2018: Psychiatry Investigation
Ather Muneer, Rana Mazommil
Objective: Staging of psychiatric disorders is gaining momentum and the purpose of this review is to examine whether major mood disorders can be defined according to stages. Methods: In April 2018 the PubMed electronic data base was scrutinized by a combination of various search terms like "major depressive disorder and staging," "bipolar disorder and neuroprogression," etc. To incorporate the latest findings the search was limited to the last 10 years...
August 2018: Psychiatry Investigation
Hoseon Lee, Joonho Choi, Myung Soo Lee, Jong-Woo Paik, Jun Soo Kwon
No abstract text is available yet for this article.
August 2018: Psychiatry Investigation
Jung Hyun Kim, Tak Youn, Jun Gwon Choi, Seong Hoon Jeong, Hee Yeon Jung, Yong Sik Kim, In Won Chung
Objective: This study aimed to investigate the effectiveness and tolerability of the combination of electroconvulsive therapy (ECT) in patients with clozapine-treated schizophrenia. Methods: Patients with clozapine-treated schizophrenia during five years of pre-determined period were recruited from Electronic Medical Record. Clinical effects of acute ECT on psychotic symptoms were investigated. We also tried to identify predictive variables requiring maintenance treatment of ECT...
August 2018: Psychiatry Investigation
Ji Won Han, Tae Hui Kim, Kyung Phil Kwak, Kayoung Kim, Bong Jo Kim, Shin Gyeom Kim, Jeong Lan Kim, Tae Hyun Kim, Seok Woo Moon, Jae Young Park, Joon Hyuk Park, Seonjeong Byun, Seung Wan Suh, Ji Young Seo, Yoonseop So, Seung-Ho Ryu, Jong Chul Youn, Kyoung Hwan Lee, Dong Young Lee, Dong Woo Lee, Seok Bum Lee, Jung Jae Lee, Ju Ri Lee, Hyeon Jeong, Hyun-Ghang Jeong, Jin Hyeong Jhoo, Kyuhee Han, Jong Woo Hong, Ki Woong Kim
Objective: Due to an unprecedented rate of population aging, South Korea is facing a dementia epidemic. For this reason, the Korean Longitudinal Study on Cognitive Aging and Dementia (KLOSCAD) was launched in 2009 with support from the Korean Health Industry Development Institute to investigate the epidemiology, biopsychosocial risk factors, and outcomes of dementia and dementia-related conditions. Methods: The KLOSCAD is the first nationwide multi-center population-based prospective cohort study...
August 2018: Psychiatry Investigation
Sang-Shin Lee, Hyo-Deog Rim, Seung-Hee Won, Jungmin Woo
Objective: To identify attachment insecurity as an associative factor with unresolved psychological distress 1 year after surgery in the early breast cancer (BC) population. Methods: One-hundred fourteen participants completed the Hospital Anxiety and Depression Scale (HADS) and the Experiences in Close Relationship (ECR-M36) questionnaire within 1 week (baseline) and at 1-year post-surgery (follow-up). Participants were categorized into the distress and the non-distress groups based on a HADS-total score cut-off of 15...
August 2018: Psychiatry Investigation
Danbi Yang, Ji-Won Hur, Yoo Bin Kwak, Sung-Won Choi
Objective: The purpose of this meta-analysis was to determine the applicability of web-based treatment programs for individuals with depression and quality of life impairments. Methods: We conducted database and manual searches using imprecise search-term strategy and inclusion criteria. Research published from 2005 to December 2015 was included in this study. Upon review, a total of 12 published papers on web-based intervention for individuals with depression were assessed eligible for this meta-analysis...
August 2018: Psychiatry Investigation
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