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Psychiatry Investigation

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https://www.readbyqxmd.com/read/27909459/a-case-of-ileus-in-a-patient-with-schizophrenia-under-paliperidone-palmitate-treatment
#1
Serdar Süleyman Can, Esra Kabadayı
Constipation is a side effect of antipsychotic drugs that have high affinity for muscarinic cholinergic receptors. In addition, ileus is an important side effect of antipsychotic treatment, with potentially morbid and mortal consequences if early detection fails. In this report, a colonic ileus case is described in a patient with schizophrenia under the treatment of paliperidone palmitate. Consequently, complete physical examination and close screening of side effects are recommended when antipsychotics are prescribed...
November 2016: Psychiatry Investigation
https://www.readbyqxmd.com/read/27909458/the-association-between-post-stroke-depression-and-the-activities-of-daily-living-gait-balance-in-patients-with-first-onset-stroke-patients
#2
Geun-Young Park, Sun Im, Soo-Jung Lee, Chi-Un Pae
This study evaluated the association between post-stroke depression (PSD) and clinical outcomes, including activities of daily living (ADL) and gait balance, in patients with first-onset stroke. One hundred and eighty inpatients were recruited and followed-up for a 6-month. The depressive, cognitive, and stroke symptoms were assessed using the Beck Depression Inventory (BDI), the Global Deterioration Scale (GDS), the modified Rankin Scale (MRS), and the Berg Balance Scale (BBS). All patients were assessed at baseline and at the end of the observation (6-month)...
November 2016: Psychiatry Investigation
https://www.readbyqxmd.com/read/27909457/the-severity-of-sleep-disordered-breathing-induces-different-decrease-in-the-oxygen-saturation-during-rapid-eye-movement-and-non-rapid-eye-movement-sleep
#3
Eunkyung Choi, Doo-Heum Park, Jae-Hak Yu, Seung-Ho Ryu, Ji-Hyeon Ha
OBJECTIVE: To investigate how differences in oxygen saturation between non-REM (NREM) and REM sleep in patients according to the severity of sleep apnea. METHODS: We studied 396 male patients diagnosed with simple snoring or obstructive sleep apnea syndrome (OSAS) on nocturnal polysomnography. Patients were divided into groups by the OSAS severity. We compared the average oxygen saturation between REM and NREM sleep in each group. RESULTS: In the simple snoring group, average oxygen saturation was significantly greater during REM than during NREM sleep...
November 2016: Psychiatry Investigation
https://www.readbyqxmd.com/read/27909456/serum-cytokine-levels-in-major-depressive-disorder-and-its-role-in-antidepressant-response
#4
Woojae Myung, Shinn-Won Lim, Hye In Woo, Jin Hong Park, Sanghong Shim, Soo-Youn Lee, Doh Kwan Kim
OBJECTIVE: Cytokines have been reported to have key roles in major depressive disorder (MDD). However, much less is known about cytokines in MDD and antidepressant treatment due to the diversity of cytokines and the heterogeneity of depression. We investigated the levels of cytokines in patients with MDD compared with healthy subjects and their associations with antidepressant response. METHODS: We investigated the changes of several cytokines (eotaxin, sCD40L, IL-8, MCP-1alpha, TNF-alpha, INF-gamma and MIP-1alpha) by Luminex assay in 66 patients with MDD and 22 healthy controls...
November 2016: Psychiatry Investigation
https://www.readbyqxmd.com/read/27909455/salivary-testosterone-levels-under-psychological-stress-and-its-relationship-with-rumination-and-five-personality-traits-in-medical-students
#5
Reza Afrisham, Sahar Sadegh-Nejadi, Omid SoliemaniFar, Wesam Kooti, Damoon Ashtary-Larky, Fatima Alamiri, Mohammad Aberomand, Sedigheh Najjar-Asl, Ali Khaneh-Keshi
OBJECTIVE: The purpose of this study was to evaluate the salivary testosterone levels under psychological stress and its relationship with rumination and five personality traits in medical students. METHODS: A total of 58 medical students, who wanted to participate in the final exam, were selected by simple random sampling. Two months before the exam, in the basal conditions, the NEO Inventory short form, and the Emotional Control Questionnaire (ECQ) were completed...
November 2016: Psychiatry Investigation
https://www.readbyqxmd.com/read/27909454/linkage-and-association-analyses-of-schizophrenia-with-genetic-variations-on-chromosome-22q11-in-koreans
#6
Se Chang Yoon, Yong Lee Jang, Jong-Won Kim, Eun-Young Cho, Dong Yeon Park, Kyung Sue Hong, Yu Sang Lee
OBJECTIVE: Chromosome 22q11 has been implicated as a susceptibility locus of schizophrenia. It also contains various candidate genes for which evidence of association with schizophrenia has been reported. To determine whether genetic variations in chromosome 22q11 are associated with schizophrenia in Koreans, we performed a linkage analysis and case-control association study. METHODS: Three microsatellite markers within a region of 4.35 Mb on 22q11 were genotyped for 47 multiplex schizophrenia families, and a non-parametric linkage analysis was applied...
November 2016: Psychiatry Investigation
https://www.readbyqxmd.com/read/27909453/the-effect-of-high-frequency-repetitive-transcranial-magnetic-stimulation-on-occupational-stress-among-health-care-workers-a-pilot-study
#7
Young In Kim, Sun Mi Kim, Hyungjin Kim, Doug Hyun Han
OBJECTIVE: Repetitive transcranial magnetic stimulation (rTMS) was approved by the Food and Drug Administration to alleviate symptoms of treatment-resistant depression. This study aimed to evaluate the effectiveness of rTMS treatment on alleviating occupational stress by evaluating clinical symptoms and quantitative electroencephalography (QEEG). METHODS: Twenty-four health care workers were randomized to receive 12 sessions of active or sham rTMS delivered to the left dorsolateral prefrontal cortex (DLPFC)...
November 2016: Psychiatry Investigation
https://www.readbyqxmd.com/read/27909452/the-levels-of-cortisol-and-oxidative-stress-and-dna-damage-in-child-and-adolescent-victims-of-sexual-abuse-with-or-without-post-traumatic-stress-disorder
#8
Şeref Şimşek, Tuğba Yüksel, İbrahim Kaplan, Cem Uysal, Hüseyin Aktaş
OBJECTIVE: The aim of this study was to investigate whether cortisol and oxidative stress levels and DNA damage differ between individuals who developed PTSD or not following a sexual trauma. METHODS: The study included 61 children aged between 5 and 17 years who sustained sexual abuse (M/F: 18/43). The patients were divided into two groups: patients with PTSD and patients without PTSD based, based on the results of a structured psychiatric interview (K-SADS-PL and CAPS-CA)...
November 2016: Psychiatry Investigation
https://www.readbyqxmd.com/read/27909451/gender-differences-in-somatic-symptoms-and-current-suicidal-risk-in-outpatients-with-major-depressive-disorder
#9
Hong Jin Jeon, Jong-Min Woo, Hyo-Jin Kim, Maurizio Fava, David Mischoulon, Seong Jin Cho, Sung Man Chang, Doo-Heum Park, Jong Woo Kim, Ikki Yoo, Jung-Yoon Heo, Jin Pyo Hong
OBJECTIVE: Although somatic symptoms are common complaints of patients with major depressive disorder (MDD), their associations with suicide are still unclear. METHODS: A total of 811 MDD outpatients of aged between 18 to 64 years were enrolled nationwide in Korea with the suicidality module of the Mini-International Neuropsychiatric Interview (MINI) and the Depression and Somatic Symptom Scale (DSSS). RESULTS: On stepwise regression analysis, current suicidality scores were most strongly associated with chest pain in men, and neck or shoulder pain in women...
November 2016: Psychiatry Investigation
https://www.readbyqxmd.com/read/27909450/evaluation-of-a-functional-model-of-acquired-capability-for-suicide-in-a-nationwide-sample-of-korean-adults
#10
Joon Deuk Lee, Maeng Je Cho, Jee Hoon Sohn, Subin Park, Sujeong Seong, Joon Ho Ahn, Bong-Jin Hahm, Jin Pyo Hong
OBJECTIVE: We examined a functional model of acquired capability for suicide, which was elaborated from the "Interpersonal-Psychological Theory of Suicide". METHODS: A total of 6,027 Korean community subjects were recruited from The Korean Epidemiologic Catchment Area study conducted in 2011. The subjects were assessed systematically using the Korean version of the Composite International Diagnostic Interview version 2.1, the Korean version of the Barratt Impulsiveness Scale, and the Korean version of the Mood Disorder Questionnaire...
November 2016: Psychiatry Investigation
https://www.readbyqxmd.com/read/27909449/association-between-dsm-iv-anxiety-disorders-and-suicidal-behaviors-in-a-community-sample-of-south-korean-adults
#11
Seong-Jin Cho, Jin Pyo Hong, Jun-Young Lee, Jeong Soo Im, Kyoung-Sae Na, Jee Eun Park, Maeng Je Cho
OBJECTIVE: There are conflicting reports about whether individual anxiety disorders are independently associated with suicidal ideation and suicide attempts. We examined whether anxiety disorders are related to suicidal ideation and suicide attempts in a community sample of South Korean adults. METHODS: In-person interviews based on the South Korean version of the Composite International Diagnostic Interview were conducted to diagnose mental disorders. Multivariate logistic regression analysis was performed to examine whether anxiety disorders were associated with suicidal ideation and suicide attempts...
November 2016: Psychiatry Investigation
https://www.readbyqxmd.com/read/27909448/a-comparative-study-of-computerized-memory-test-and-the-korean-version-of-the-consortium-to-establish-a-registry-for-alzheimer-s-disease-assessment-packet-for-assessing-memory-function-in-the-elderly
#12
Min-Sup Shin, Jayun Choi, Ryu-Yeon Ahn, Dong-Young Lee, Jun-Soo Kwon
OBJECTIVE: The aim of this study was to examine the concurrent validity of a newly developed computerized memory diagnostic system (MDS) with the Korean version of the Consortium to Establish a Registry for Alzheimer's Disease Assessment Packet (CERAD-K). METHODS: Subtests of the MDS and CERAD-K, including the auditory-verbal, visuo-spatial, and working memory tests, were administered to 43 adults aged 60 to 74 years. We calculated the correlations between the subtest scores of the MDS and CERAD-K to examine the concurrent validity of the MDS...
November 2016: Psychiatry Investigation
https://www.readbyqxmd.com/read/27909447/stem-cell-therapy-a-prospective-treatment-for-alzheimer-s-disease
#13
REVIEW
Ji Han Lee, Il-Hoan Oh, Hyun Kook Lim
Alzheimer's disease (AD) without cure remains as a serious health issue in the modern society. The major neuropathological alterations in AD are characterized by chronic neuroinflammation and neuronal loss due to neurofibrillary tangles (NFTs) of abnormally hyperphosphorylated tau, plaques of β-amyloid (Aβ) and various metabolic dysfunctions. Due to the multifaceted nature of AD pathology and our limited understanding on its etiology, AD is difficult to be treated with currently available pharmaceuticals...
November 2016: Psychiatry Investigation
https://www.readbyqxmd.com/read/27757140/bipolar-and-related-disorders-induced-by-sodium-4-phenylbutyrate-in-a-male-adolescent-with-bile-salt-export-pump-deficiency-disease
#14
Giovanni Vitale, Giulia Simonetti, Martina Pirillo, Gianfranco Taruschio, Pietro Andreone
Bile Salt Export Pump (BSEP) Deficiency disease, including Progressive Familial Intrahepatic Cholestasis type 2 (PFIC2), is a rare disease, usually leading within the first ten years to portal hypertension, liver failure, hepatocellular carcinoma. Often liver transplantation is needed. Sodium 4-phenylbutyrate (4-PB) seems to be a potential therapeutic compound for PFIC2. Psychiatric side effects in the adolescent population are little known and little studied since the drug used to treat children and infants...
September 2016: Psychiatry Investigation
https://www.readbyqxmd.com/read/27757139/charles-bonnet-syndrome-following-trans-sphenoidal-adenomectomy-without-optic-nerve-atrophy
#15
Jang-Ho Park, Joon-Ho Ahn, Jun-Bum Park, Soohyun Joe
Charles Bonnet syndrome (CBS) can develop after trans-sphenoidal adenomectomy (TSA); however, the neural mechanisms remain unknown. Sensory deprivation and releasing phenomenon are both hypothetical explanations for this condition; however, there is no definite evidence that strongly supports either supposition. We report the first case of CBS after TSA without optic nerve atrophy. Postoperatively, the patient's vision seemed to be relatively well preserved, apart from the left-side hemianopsia in the right eye...
September 2016: Psychiatry Investigation
https://www.readbyqxmd.com/read/27757138/considering-comorbidity-in-adolescents-with-social-anxiety-disorder
#16
Luis-Joaquin Garcia-Lopez, Natalia Bonilla, Jose-Antonio Muela-Martinez
Social anxiety disorder is a highly prevalent psychiatric disorder, with elevated comorbidity rates with other mental health disorders and may cause severe negative consequences. In adolescence, there is a lack of research on how comorbid disorders to social anxiety tends to form particular associations. With a large sample of adolescents with a clinical diagnosis of social anxiety disorder, data have revealed that certain disorders are more frequent and tend to dwell on concrete aggregates. Thus, it may be particularly useful and efficient for mental health providers, pediatricians and school counselors to screen for generalized anxiety disorder and specific phobia when assessing SAD in youth...
September 2016: Psychiatry Investigation
https://www.readbyqxmd.com/read/27757137/the-thai-version-of-the-addenbrooke-s-cognitive-examination-iii
#17
Thammanard Charernboon, Kankamol Jaisin, Tiraya Lerthattasilp
The objective of our study was to assess the accuracy of the Thai version of the Addenbrooke's Cognitive Examination III (ACE-T). We used the ACE-T to assess 107 participants aged 60 or over, divided into the following groups: early dementia, n=30; mild cognitive impairment (MCI), n=29; and normal controls (NC), n=48. The ACE-T exhibited good internal consistency (0.93) and inter-rater reliability (1.0). The optimal cut-off score for the ACE-T to differentiate MCI from NC was 75/76, giving a sensitivity of 0...
September 2016: Psychiatry Investigation
https://www.readbyqxmd.com/read/27757136/the-relationship-between-personality-sense-of-efficacy-and-stress-in-korean-teachers
#18
Subin Park, Yul-Mai Song, Guy-Nueo Ko, Kyungun Jhung, Kyooseob Ha, Young-Ryeol Lee, Yeni Kim
Several studies have linked teachers' personality characteristics and sense of efficacy to stress. However, investigating the relationship between these three constructs in this context was limited. This study aims to investigate the relationship between personality, sense of efficacy and perceived stress among Korean teachers. A total of 137 teachers working in elementary, middle, and high schools located in Seoul, South Korea were recruited for the study. The participants were administered Temperament and Character Inventory, Teacher's Sense of Efficacy Scale (TSES), and Perceived Stress Scale...
September 2016: Psychiatry Investigation
https://www.readbyqxmd.com/read/27757135/what-does-depression-mean-for-korean-american-elderly-a-qualitative-follow-up-study
#19
Su Yeon Lee-Tauler, Seung Hee Lee-Kwan, Haera Han, Hochang B Lee, Joseph J Gallo, Jin Hui Joo
OBJECTIVE: Korean American Elderly (KAE) have high rates of depression but underuse mental health services. The purpose of this study was to assess the meaning of depression and help seeking among KAE residing in the United States who have clinically significant depressive symptoms. METHODS: As a follow up to the Memory and Aging Study of Koreans (MASK; n=1,118), a descriptive epidemiological study which showed that only one in four of KAE with clinically significant depressive symptoms (Patient Health Questionnaire-9≥10) used mental health services, we conducted a qualitative study using semi-structured interviews with participants with clinically significant depressive symptoms regarding the meaning of depression and beliefs about help seeking...
September 2016: Psychiatry Investigation
https://www.readbyqxmd.com/read/27757134/circulating-plasma-micro-rnas-in-patients-with-major-depressive-disorder-treated-with-antidepressants-a-pilot-study
#20
Virgil Radu Enatescu, Ion Papava, Ileana Enatescu, Mirela Antonescu, Andrei Anghel, Edward Seclaman, Ioan Ovidiu Sirbu, Catalin Marian
OBJECTIVE: Significant progress was made in the understanding etiopathogenic factors related to MDD, including through research on the role of micro RNAs (miRs). We investigated plasma miRs as potential markers for MDD in patients treated with antidepressants. METHODS: At the initiation and at the end of twelve weeks of treatment, blood samples were collected and a structured diagnostic interview and a standardized depression rating scale for the presence and severity of major depression were done...
September 2016: Psychiatry Investigation
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