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Clinical Toxicology

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https://www.readbyqxmd.com/read/28447890/response-to-the-letter-regarding-is-it-really-safe-to-withhold-folinic-acid-when-less-than-1000%C3%A2-mg-m-2-methotrexate-is-ingested
#1
Betty S Chan, Andrew H Dawson, Nicholas A Buckley
No abstract text is available yet for this article.
April 27, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28447886/drug-induced-hyperlactatemia
#2
Eike Blohm, Jeffrey Lai, Mark Neavyn
BACKGROUND: Hyperlactatemia is common in critically ill patients and has a variety of etiologies. Medication toxicity remains an uncommon cause that providers often fail to recognize. In this article, we review several medications that cause hyperlactatemia in either therapeutic or supratherapeutic dosing. When known, the incidence, mortality, pathophysiology, and treatment options are discussed. METHODS: We performed a literature search using PUBMED and Google Scholar for English language articles published after 1980 regarding medication induced hyperlactatemia and its management...
April 27, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28447858/risk-prediction-of-hepatotoxicity-in-paracetamol-poisoning
#3
Anselm Wong, Andis Graudins
CONTEXT: Paracetamol (acetaminophen) poisoning is the most common cause of acute liver failure in the developed world. A paracetamol treatment nomogram has been used for over four decades to help determine whether patients will develop hepatotoxicity without acetylcysteine treatment, and thus indicates those needing treatment. Despite this, a small proportion of patients still develop hepatotoxicity. More accurate risk predictors would be useful to increase the early detection of patients with the potential to develop hepatotoxicity despite acetylcysteine treatment...
April 27, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28443386/association-of-renal-function-and-symptoms-with-mortality-in-star-fruit-averrhoa-carambola-intoxication
#4
Choon-Bing Chua, Cheuk-Kwan Sun, Huan-Wen Tsui, Po-Jen Yang, Kuo-Hsin Lee, Chih-Wei Hsu, I-Ting Tsai
BACKGROUND: Star fruit (SF) is a commonly available fruit produced and eaten in tropical and subtropical countries. Since 1993, various reports have described neurotoxicity after eating SF, but this clinical condition remains unfamiliar. We aimed to describe this clinical entity, the role of renal dysfunction in this disorder, treatment strategies, and prognosis of patients with SF intoxication. METHODS: We conducted a search of PubMed and Google Scholar databases from 1993 to 2016...
April 26, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28443380/acute-hypersensitivity-reaction-to-crotalidae-polyvalent-immune-fab-crofab-as-initial-presentation-of-galactose-%C3%AE-1-3-galactose-%C3%AE-gal-allergy
#5
Justin Rizer, Kaitlin Brill, Nathan Charlton, Joshua King
Crotalidae polyvalent immune Fab antivenom (CroFab), commonly used for the treatment of clinically significant North American crotalinae envenomation, is generally well-tolerated. A novel form of anaphylaxis due to an IgE antibody response to the mammalian oligosaccharide galactose-α-1,3-galactose (α-gal) has been established following red-meat consumption as well as IV administration of cetuximab, which contain the α-gal epitope. We present a case of α-gal allergy discovered after acute hypersensitivity reaction to FabAV...
April 26, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28443378/toxicity-resulting-from-exposure-to-oven-cleaners-as-reported-to-the-uk-national-poisons-information-service-npis-from-2009-to-2015
#6
Rachael C Day, Sally M Bradberry, Euan A Sandilands, Simon H L Thomas, John P Thompson, J Allister Vale
INTRODUCTION: Oven cleaning products contain corrosive substances, typically sodium or potassium hydroxide. OBJECTIVE: To determine the reported toxicity from exposure to oven cleaning products. METHODS: Telephone enquiries to the UK National Poisons Information Service regarding oven cleaning products were analysed retrospectively for the period January 2009 to December 2015. RESULTS: There were 796 enquiries relating to 780 patients...
April 26, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28443374/is-it-really-safe-to-withhold-folinic-acid-when-less-than-1000%C3%A2-mg-m-2-methotrexate-is-ingested
#7
Arjen Koppen, Marieke A Dijkman, Claudine C Hunault, Dylan W de Lange, Irma de Vries
No abstract text is available yet for this article.
April 26, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28443353/anticholinergic-toxicity-associated-with-ingestion-of-water-containing-lupini-bean-extract
#8
Kai Li, Xander M R van Wijk, Sandra Hayashi, Kara L Lynch, Alan H B Wu, Craig G Smollin
No abstract text is available yet for this article.
April 26, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28438052/successful-treatment-of-no-induced-methemoglobinemia-with-low-dose-vitamin-c
#9
Eun Jung Park, Minjeong Lee, Young-Gi Min
No abstract text is available yet for this article.
April 25, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28426257/facial-eschar-following-a-single-application-of-black-salve
#10
Dayne Laskey, Midori Tran
A previously healthy 86-year-old male was transported by ambulance to the trauma bay of the emergency department (ED) for profuse bleeding from the left temple. The ambulance crew raised concern that the volume and force of the bleed may suggest arterial involvement. The patient reported having applied a natural topical remedy to a mole two weeks prior at the recommendation of a naturopath. The patient described progressive blackening and swelling of the area in the days following the single application of the product...
April 20, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28406329/ciemto-the-new-drug-and-poison-research-and-information-center-in-medell%C3%A3-n-colombia
#11
Andres F Zuluaga, Carlos A Rodriguez, Sara Lastra-Bello, Lina M Peña-Acevedo, Maria A Montoya-Giraldo
No abstract text is available yet for this article.
April 13, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28406320/underestimated-impact-of-novel-psychoactive-substances-laboratory-confirmation-of-recreational-drug-toxicity-in-oslo-norway
#12
Odd Martin Vallersnes, Per Sverre Persett, Elisabeth Leere Øiestad, Ritva Karinen, Fridtjof Heyerdahl, Knut Erik Hovda
CONTEXT: Recreational drug toxicity is frequent. Availability of new psychoactive substances is steadily increasing. However, data with verified analyses from clinical settings are limited. To evaluate the impact of novel psychoactive substances (NPS) on recreational drug toxicity in Oslo, Norway, we analysed samples from a selection of patients. METHODS: All the patients presenting with recreational drug toxicity at the Oslo Accident and Emergency Outpatient Clinic (OAEOC) and at the Oslo University Hospital (OUH) were registered from April through September 2014...
April 13, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28403678/37th-international-congress-of-the-european-association-of-poisons-centres-and-clinical-toxicologists-eapcct-16-19-may-2017-basel-switzerland
#13
(no author information available yet)
No abstract text is available yet for this article.
April 13, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28394637/severe-neutrophilic-dermatosis-following-submental-deoxycholic-acid-administration
#14
Bryan T Mogle, Robert W Seabury, Shane Jennings, Gregory M Cwikla
No abstract text is available yet for this article.
April 10, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28393558/supraventricular-tachycardia-and-acute-confusion-following-ingestion-of-e-cigarette-fluid-containing-ab-fubinaca-and-adb-fubinaca-a-case-report-with-quantitative-analysis-of-serum-drug-concentrations
#15
Rex Pui Kin Lam, Magdalene Huen Yin Tang, Siu Chung Leung, Yeow Kuan Chong, Matthew Sik Hon Tsui, Tony Wing Lai Mak
BACKGROUND: AB-FUBINACA and ADB-FUBINACA are structurally similar synthetic cannabinoids with potent CB1 receptor agonistic effects. Very little is known about their pharmacology and toxicology. OBJECTIVE: To report a case of supraventricular tachycardia and acute confusion after ingestion of e-cigarette fluid containing AB-FUBINACA and ADB-FUBINACA, with quantitative analysis of the serum drug concentrations. CASE REPORT: A healthy 24-year-old man ingested two drops of e-cigarette fluid which were later found to contain AB-FUBINACA and ADB-FUBINACA...
April 10, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28393553/analysis-of-intentional-drug-poisonings-using-ohio-poison-control-center-data-2002-2014
#16
Kelsey Pringle, Sarah Caupp, Junxin Shi, Krista K Wheeler, Henry A Spiller, Marcel J Casavant, Henry Xiang
CONTEXT: Pharmaceutical drug poisonings, especially those that are intentional, are a serious problem for adolescents and young adults. Poison control center data is a viable tool to track intentional drug poisonings in near real-time. OBJECTIVE: To determine intentional drug poisoning rates among adolescents and young adults in Ohio using poison control center data. METHODS: We analyzed data from 2002 to 2014 obtained by Ohio's three poison control centers...
April 10, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28367646/ischemic-stroke-due-to-wasp-sting-a-case-report
#17
Xi Tao, Liang Huang, Cuini Fang, Chujuan Liu, Liang Qing, Huaan Cai
No abstract text is available yet for this article.
April 3, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28349783/toxicity-from-fluoropolymer-containing-grout-tile-and-stone-floor-sealants-reported-to-the-uk-national-poisons-information-service-2009-2015
#18
Des Henke, Alex Campbell, Sally M Bradberry, Euan A Sandilands, Simon H L Thomas, John P Thompson, J Allister Vale
CONTEXT: Grout, tile and floor stone sealants contain a solvent, a water-repelling agent and in the case of aerosols a propellant. The water-repelling agent used is typically a fluoropolymer resin, a silicon-based resin, or a combination of both. OBJECTIVE: To report the clinical course in patients exposed to fluoropolymer-containing sealants referred to the United Kingdom National Poisons Information Service. METHODS: A retrospective analysis was performed of telephone enquiries received between 2009 and 2015...
March 28, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28349771/antivenom-for-european-vipera-species-envenoming
#19
Thomas Lamb, Luc de Haro, Davide Lonati, Miran Brvar, Michael Eddleston
BACKGROUND: European viper bite is relatively uncommon but can cause serious envenoming, particularly swelling and hemorrhage spreading from limb to trunk that can cause long term disability. Systemic features are relatively mild compared to many other venomous species. Moderate-to-severe envenoming requires antivenom, which is given many hundreds of times each year across the continent. Several Vipera spp antivenoms are produced in Europe, but there is little comparative information available for the antivenoms and none is licensed with the European Medicines Agency...
March 28, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28349748/rash-and-pyrexia-after-succimer-dimercaptosuccinic-acid-dmsa
#20
Anneka Varma, Sally M Bradberry, J Allister Vale
No abstract text is available yet for this article.
March 28, 2017: Clinical Toxicology
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