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Neuropsychiatric Disease and Treatment

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https://www.readbyqxmd.com/read/27920539/comparison-of-self-stigma-and-quality-of-life-in-patients-with-depressive-disorders-and-schizophrenia-spectrum-disorders-a-cross-sectional-study
#1
Michaela Holubova, Jan Prasko, Stanislav Matousek, Klara Latalova, Marketa Marackova, Kristyna Vrbova, Aleš Grambal, Milos Slepecky, Marta Zatkova
BACKGROUND: The views of one's self-stigma and quality of life (QoL) in patients with schizophrenia and depressive disorders are significant subjective notions, both being proven to affect patient's functioning in life. The objective of this study was to investigate the QoL and self-stigma in connection with demographic factors and compare the two groups of patients in terms of those variables. METHODS: In a cross-sectional study, the outpatients with schizophrenia spectrum disorders and depressive disorders completed the Quality of Life Satisfaction and Enjoyment Questionnaire, the Internalized Stigma of Mental Illness Scale, and a demographic questionnaire during a routine psychiatric control...
2016: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/27920538/self-stigma-and-schizophrenia-a-cross-sectional-study
#2
Kristyna Vrbova, Jan Prasko, Michaela Holubova, Dana Kamaradova, Marie Ociskova, Marketa Marackova, Klara Latalova, Ales Grambal, Milos Slepecky, Marta Zatkova
OBJECTIVE: The aim of this study was to investigate the degree of self-stigma in schizophrenia and its association with clinical and demographic factors. PATIENTS AND METHODS: A total of 197 outpatients (54.3% females) diagnosed with schizophrenia spectrum disorders (schizophrenia, schizoaffective disorder, delusional disorder) according to International Classification of Diseases - tenth edition participated in the study. The mean age of the patients was 40.10±11...
2016: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/27920537/factors-related-to-depression-and-anxiety-in-adults-with-bronchiectasis
#3
Elif Yelda Özgün Niksarlioglu, Gülcihan Özkan, Gülşah Günlüoğlu, Mehmet Atilla Uysal, Sule Gül, Lütfiye Kilic, Ayse Yeter, Güngör Çamsarı
INTRODUCTION AND BACKGROUND: Patients with chronic lung diseases frequently have depressive and anxiety symptoms, but there are very few studies looking at this in patients with bronchiectasis. AIM: This study aimed to investigate depression and anxiety and related factors among patients with non-cystic fibrosis bronchiectasis. PATIENTS AND METHODS: This was a prospective study of 133 patients with bronchiectasis. Patients with confirmed diagnosis of bronchiectasis with high-resolution computed tomography were enrolled in the study...
2016: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/27920536/evaluation-of-potential-novel-variations-and-their-interactions-related-to-bipolar-disorders-analysis-of-genome-wide-association-study-data
#4
Cengizhan Acikel, Yesim Aydin Son, Cemil Celik, Husamettin Gul
BACKGROUND: Multifactor dimensionality reduction (MDR) is a nonparametric approach that can be used to detect relevant interactions between single-nucleotide polymorphisms (SNPs). The aim of this study was to build the best genomic model based on SNP associations and to identify candidate polymorphisms that are the underlying molecular basis of the bipolar disorders. METHODS: This study was performed on Whole-Genome Association Study of Bipolar Disorder (dbGaP [database of Genotypes and Phenotypes] study accession number: phs000017...
2016: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/27920535/prevalence-of-alcohol-use-disorders-and-associated-factors-among-people-with-epilepsy-attending-amanuel-mental-specialized-hospital-addis-ababa-ethiopia
#5
Tsegereda Waja, Jemal Ebrahim, Zegeye Yohannis, Asres Bedaso
INTRODUCTION: Alcohol use disorders represent one of the leading causes of preventable death, illness, and injury in many societies throughout the world. Heavy alcohol consumption has multiple negative consequences for people with epilepsy such as precipitation of seizure, exacerbation of seizure, poor seizure control, increased side effects of antiepileptic drugs, noncompliance to antiepileptic drugs, alcohol withdrawal seizures, long-term hospital admission, status epilepticus, sudden unexpected death, and premature mortality...
2016: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/27920534/perceptions-and-impact-of-bipolar-disorder-in-japan-results-of-an-internet-survey
#6
Koichiro Watanabe, Eiji Harada, Takeshi Inoue, Yuka Tanji, Toshiaki Kikuchi
Bipolar disorder is a recurrent and episodic illness. This survey study assessed experiences and identified clinical insights of individuals with bipolar disorder. An Internet-based monitor system database was screened for patients with bipolar disorder in Japan (February and March 2013). Of 1,050 patients, 457 completed surveys, and results were analyzed with descriptive statistics. Approximately one-fourth of respondents were diagnosed with bipolar disorder on their first visit to medical institutions, although the most common initial diagnosis was depression/depressive state (65%)...
2016: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/27895486/factors-associated-with-vitamin-d-status-of-low-income-hospitalized-psychiatric-patients-results-of-a-retrospective-study
#7
Alessandra N Bazzano, Lisa Littrell, Stephen Lambert, Cody Roi
BACKGROUND: Recent evidence has indicated a potential role of vitamin D3 in a range of neuropsychiatric outcomes, as well as on cognitive function, but conflicting data have left that role uncertain. Understanding potential associations of vitamin D status with psychiatric illness will allow clinicians to better assess therapeutic options. Few studies have examined vitamin D status among a racially diverse group of psychiatric patients who have been hospitalized, and none has done so in the southern US where socioeconomic inequality is high...
2016: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/27895485/adhd-and-present-hedonism-time-perspective-as-a-potential-diagnostic-and-therapeutic-tool
#8
REVIEW
S Weissenberger, M Klicperova-Baker, P Zimbardo, K Schonova, D Akotia, J Kostal, M Goetz, J Raboch, R Ptacek
The article draws primarily from the behavioral findings (mainly psychiatric and psychological observations) and points out the important relationships between attention-deficit/hyperactivity disorder (ADHD) symptoms and time orientation. Specifically, the authors argue that there is a significant overlap between the symptoms of ADHD and Present Hedonism. Present Hedonism is defined by Zimbardo's time perspective theory and assessed by Zimbardo Time Perspective Inventory. Developmental data on Present Hedonism of males and females in the Czech population sample (N=2201) are also presented...
2016: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/27881921/the-occurrence-and-predictive-factors-of-sleep-paralysis-in-university-students
#9
Monika Lišková, Denisa Janečková, Lucie Klůzová Kráčmarová, Karolína Mladá, Jitka Bušková
The aim of the present study was to assess the occurrence and predictive factors of sleep paralysis (SP) in Czech university students. Our sample included 606 students who had experienced at least one episode of SP. The participants completed an online battery of questionnaires involving questionnaires focused on describing their sleep habits and SP episodes, the 18-item Boundary Questionnaire (BQ-18), the Modified Tellegen Absorption Scale (MODTAS), the Dissociative Experience Scale Taxon, the Beck Depression Inventory II and the State-Trait Anxiety Inventory...
2016: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/27881920/altered-spontaneous-brain-activity-pattern-in-patients-with-high-myopia-using-amplitude-of-low-frequency-fluctuation-a-resting-state-fmri-study
#10
Xin Huang, Fu-Qing Zhou, Yu-Xiang Hu, Xiao-Xuan Xu, Xiong Zhou, Yu-Lin Zhong, Jun Wang, Xiao-Rong Wu
OBJECTIVE: Many previous reports have demonstrated significant neural anatomy changes in the brain of high myopic (HM) patients, whereas the spontaneous brain activity changes in the HM patients at rest are not well studied. Our objective was to use amplitude of low-frequency fluctuation (ALFF) method to investigate the changes in spontaneous brain activity in HM patients and their relationships with clinical features. METHODS: A total of 38 patients with HM (17 males and 21 females) and 38 healthy controls (HCs) (17 males and 21 females) closely matched in age, sex, and education underwent resting-state functional magnetic resonance imaging scans...
2016: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/27881919/posttraumatic-stress-and-depression-in-yazidi-refugees
#11
Serhat Nasıroğlu, Veysi Çeri
AIM: The aim of this investigation was to determine the frequency of mental pathologies in children and adolescents of the Yazidi minority group who immigrated to Turkey from Iraq. The refugees were asked about preventive and risk factors that occurred before and after their immigration. SUBJECTS AND METHODS: The sample comprised 55 children and adolescents (30 males and 25 females) who were Yazidi refugees and had settled in the Uçkuyular, Oğuz, Onbaşı, and Uğurca villages of Batman, Turkey...
2016: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/27881918/sex-differences-in-the-course-of-schizophrenia-across-diverse-regions-of-the-world
#12
Diego Novick, William Montgomery, Tamas Treuer, Maria Victoria Moneta, Josep Maria Haro
This study explores sex differences in the outcomes of patients with schizophrenia (clinical/functional remission and recovery) across diverse regions of the world (Northern Europe, Southern Europe, Central and Eastern Europe, Latin America, East Asia, and North Africa and the Middle East). Data (n=16,380 for this post hoc analysis) were taken from the World-Schizophrenia Health Outcomes Study. In most regions, females had a later age at first service contact for schizophrenia, a lower level of overall/negative symptom severity, lower rates of alcohol/substance abuse and paid employment, and higher percentages of having a spouse/partner and independent living...
2016: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/27877045/serum-low-density-lipoprotein-levels-statin-use-and-cognition-in-patients-with-coronary-artery-disease
#13
Soham Rej, Mahwesh Saleem, Nathan Herrmann, Anthi Stefatos, Allison Rau, Krista L Lanctôt
AIM: Statins have been associated with decreased cognition due to the effects of low concentrations of low-density lipoprotein (LDL) on brain function. This has remained controversial and is particularly relevant to patients with coronary artery disease (CAD), who have an increased risk of cognitive decline and are frequently prescribed statins. This study hypothesized that low concentration of LDL is associated with poor cognition in CAD patients using statins. It also explored the association between high-dose versus low-dose statins on cognition in this population...
2016: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/27877044/increased-mir-132-level-is-associated-with-visual-memory-dysfunction-in-patients-with-depression
#14
Ye Liu, Xiao Yang, Liansheng Zhao, Jian Zhang, Tao Li, Xiaohong Ma
BACKGROUND: Impaired visual memory seems to be a core feature of depression, while increased microRNA-132 (miR-132) levels have been widely reported in depression patients. The authors aimed to explore the relationship between miR-132 changes and visual memory deficits in unmedicated patients with major depressive disorder (MDD). PATIENTS AND METHODS: A total of 62 medication-free MDD patients and 73 matched healthy controls (HCs) were tested for miR-132 expression level in peripheral blood using quantitative real-time polymerase chain reaction...
2016: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/27877043/polycystic-ovary-syndrome-and-mental-disorders-a-systematic-review-and-exploratory-meta-analysis
#15
REVIEW
Sergio Luís Blay, João Vicente Augusto Aguiar, Ives Cavalcante Passos
BACKGROUND: The association between depression, anxiety, and polycystic ovary syndrome (PCOS) is still unclear. Therefore, a systematic review and meta-analysis was conducted to assess the rates of comorbid psychiatric disorders among women with PCOS compared to women without it. METHODS: PubMed/MEDLINE, Embase, PsycINFO, and Web of Science databases were searched from inception to November 27, 2015. Studies were eligible for inclusion if they were original reports in which the rates of mood (bipolar disorder, dysthymia, or major depressive disorder), obsessive-compulsive spectrum disorders, trauma- and stressor-related disorders, anxiety disorders or psychotic disorders, somatic symptom and related disorders, or eating disorders had been investigated among women with an established diagnosis of PCOS and compared with women without PCOS...
2016: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/27853372/post-stroke-dyskinesias
#16
REVIEW
Mohammad Obadah Nakawah, Eugene C Lai
Strokes, whether ischemic or hemorrhagic, are among the most common causes of secondary movement disorders in elderly patients. Stroke-related (vascular) movement disorders, however, are uncommon complications of this relatively common disease. The spectrum of post-stroke movement disorders is broad and includes both hypo- and hyperkinetic syndromes. Post-stroke dyskinesias are involuntary hyperkinetic movements arising from cerebrovascular insults and often present with mixed phenotypes of hyperkinesia which can sometimes be difficult to classify...
2016: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/27853371/the-ncan-gene-schizophrenia-susceptibility-and-cognitive-dysfunction
#17
Peirong Wang, Jun Cai, Jianliang Ni, Jiangtao Zhang, Wei Tang, Chen Zhang
BACKGROUND: Cognitive dysfunction has been recognized as a cardinal feature of schizophrenia. Elucidating the neurobiological substrates of cognitive dysfunction in schizophrenia would help identify the underlying mechanism of this disorder. The rs1064395 single nucleotide polymorphism, within the gene encoding neurocan (NCAN), is reported to be associated with schizophrenia in European populations and may influence brain structure in patients with schizophrenia. METHODS: In this study, we aimed to explore whether NCAN rs1064395 confers some risk for schizophrenia and cognitive dysfunction in Han Chinese...
2016: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/27843322/the-reduction-of-csf-tumor-necrosis-factor-alpha-levels-in-schizophrenia-no-correlations-with-psychopathology-and-coincident-metabolic-characteristics
#18
Haibing Zhu, Danfeng Wang, Xiuqin Liu
AIM: The aim of this study was to assess whether tumor necrosis factor alpha (TNF-α) levels are correlated with the behavioral syndrome of schizophrenia and/or metabolic abnormalities. METHODS: Sixty patients with first-onset schizophrenia were recruited. The concentrations of TNF-α in the cerebrospinal fluid (CSF) were determined in 22 schizophrenia patients and ten patients with nonsuppurative appendicitis using a radioimmunoassay. Physiological characteristics such as fasting blood glucose, fasting insulin, triglycerides, corrected QT interval, waist circumference, and body mass index were measured prior to CSF collection...
2016: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/27843321/efficacy-of-ketamine-in-the-rapid-treatment-of-major-depressive-disorder-a-meta-analysis-of-randomized-double-blind-placebo-controlled-studies
#19
Yu Han, Jianjun Chen, Dezhi Zou, Peng Zheng, Qi Li, Haiyang Wang, Pengfei Li, Xinyu Zhou, Yuqing Zhang, Yiyun Liu, Peng Xie
BACKGROUND: An increasing number of studies are reporting that ketamine could be treated as a novel antidepressant for major depressive disorder (MDD). Therefore, we performed this meta-analysis to comprehensively and systematically assess the efficacy of ketamine for treating patients with MDD. METHOD: Randomized, double-blind, placebo-controlled studies on ketamine versus placebo for treating MDD were searched up to April 2016 in medical databases (PubMed, CCTR, Web of Science, Embase, CBM-disc, and CNKI)...
2016: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/27843320/a-modification-of-intraluminal-middle-cerebral-artery-occlusion-reperfusion-model-for-ischemic-stroke-with-laser-doppler-flowmetry-guidance-in-mice
#20
Qiang Cai, Gang Xu, Junhui Liu, Long Wang, Gang Deng, Jun Liu, Zhibiao Chen
Stroke is one of the common causes of death and disability in the world. The intraluminal middle cerebral artery occlusion/reperfusion (MCAO/R) model is a "gold standard" in surgical ischemic stroke models. Here, we optimized the procedure of this model by ligating on external carotid artery (ECA) stump and two ligatures prepared on internal carotid artery, which could improve the success and survival rate in mice. The results show that ECA approach was superior to common carotid artery approach. Meanwhile, we found that the exposure of pterygopalatine artery was not an essential step for MCAO/R model in mice...
2016: Neuropsychiatric Disease and Treatment
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