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Neuropsychiatric Disease and Treatment

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https://www.readbyqxmd.com/read/29785113/acupuncture-in-migraine-prophylaxis-in-czech-patients-an-open-label-randomized-controlled-trial
#1
Frantisek Musil, Jitka Pokladnikova, Zbysek Pavelek, Bo Wang, Xin Guan, Martin Valis
Background: Adjuvant acupuncture for the symptomatic treatment of migraine reduces the frequency of headaches and may be at least similarly effective to treatment with prophylactic drugs. Methods: This article describes an open-label randomized controlled clinical trial with two groups: the intervention group (n=42) and the waiting-list control group (n=44). This study occurred at the Czech-Chinese Center for Traditional Chinese Medicine at the University Hospital Hradec Kralove between October 2015 and April 2017...
2018: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29785112/treatment-of-behavioral-and-psychological-symptoms-of-dementias-with-psychopharmaceuticals-a-review
#2
REVIEW
Jiří Masopust, Dita Protopopová, Martin Vališ, Zbyšek Pavelek, Blanka Klímová
Behavioral and psychological symptoms represent common complications in patients with different types of dementia. Predominantly, they comprise psychosis, agitation and mood disorders, disinhibited behavior, impairment of the sleep and wakefulness rhythm, wandering, perseveration, pathological collecting, or shouting. Their appearance is related to more rapid progression of the disease, earlier institutionalization, use of physical restraints, and higher risk of mortality. Consequently, appearance of behavioral and psychological symptoms of dementia leads to higher costs of care provided and greater distress for caregivers...
2018: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29785111/association-of-serotonin-receptor-2a-haplotypes-with-obsessive-compulsive-disorder-and-its-treatment-response-in-iranian-patients-a-genetic-and-pharmacogenetic-study
#3
Marzie Sina, Abolhassan Ahmadiani, Sareh Asadi, Jamal Shams
Introduction: Obsessive-compulsive disorder (OCD) is a debilitating psychiatric disorder causing intrusive thoughts or repetitive behaviors. Serotonin reuptake inhibitors are used for OCD treatment, but 40%-60% of patients do not respond to them adequately. In this study, the associations of serotonin receptor 2a polymorphisms rs6311 and rs6313 with OCD, its familial form and fluvoxamine treatment response in Iranian population were investigated. Patients and methods: Association analyses were conducted in 293 OCD cases fulfilling the Diagnostic and Statistical Manual of Mental Disorders (DSM)-IV-TR and 245 controls...
2018: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29785110/prefrontoparietal-dysfunction-during-emotion-regulation-in-anxiety-disorder-a-meta-analysis-of-functional-magnetic-resonance-imaging-studies
#4
Hai-Yang Wang, Xiao-Xia Zhang, Cui-Ping Si, Yang Xu, Qian Liu, He-Tao Bian, Bing-Wei Zhang, Xue-Lin Li, Zhong-Rui Yan
Objective: Impairments in emotion regulation, and more specifically in cognitive reappraisal, are thought to play a key role in the pathogenesis of anxiety disorders. However, the available evidence on such deficits is inconsistent. To further illustrate the neurobiological underpinnings of anxiety disorder, the present meta-analysis summarizes functional magnetic resonance imaging (fMRI) findings for cognitive reappraisal tasks and investigates related brain areas. Methods: We performed a comprehensive series of meta-analyses of cognitive reappraisal fMRI studies contrasting patients with anxiety disorder with healthy control (HC) subjects, employing an anisotropic effect-size signed differential mapping approach...
2018: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29773948/the-impact-of-total-sleep-deprivation-upon-cognitive-functioning-in-firefighters
#5
Sławomir Kujawski, Joanna Słomko, Małgorzata Tafil-Klawe, Monika Zawadka-Kunikowska, Justyna Szrajda, Julia L Newton, Paweł Zalewski, Jacek J Klawe
Introduction: Firefighters as a profession are required to maintain high levels of attention for prolonged periods. However, total sleep deprivation (TSD) could influence negatively upon performance, particularly when the task is prolonged and repetitive. Purpose: The aim of this study is to examine the influence of TSD on cognitive functioning in a group of firefighters. Subjects and methods: Sixty volunteers who were active male fire brigade officers were examined with a computerized battery test that consisted of simple reaction time (SRT) (repeated three times), choice reaction time, visual attention test, and delayed matching to sample...
2018: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29765220/children-with-autism-spectrum-disorders-and-selective-mutism
#6
Hanna Steffenburg, Suzanne Steffenburg, Christopher Gillberg, Eva Billstedt
Background: It has been suggested that autism spectrum disorder (ASD) might be a "comorbid" condition in selective mutism (SM). Methods: In this retrospective study, we examined medical records of children with SM diagnosis (n=97) at a medical center specializing in assessment of ASD. Results: Mean age for onset of SM symptoms was 4.5 years and mean age at SM diagnosis was 8.8 years. SM was more common among girls (boy:girl ratio=2...
2018: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29765219/estimated-prevalence-and-incidence-of-diagnosed-adhd-and-health-care-utilization-in-adults-in-sweden-a-longitudinal-population-based-register-study
#7
Maria Polyzoi, Ewa Ahnemark, Emma Medin, Ylva Ginsberg
Background: Although the worldwide prevalence of attention-deficit/hyperactivity disorder (ADHD) in adults is estimated to be between 2% and 5%, it is considered to be underdiagnosed. This register study explored the prevalence of diagnosed ADHD and incidence of newly diagnosed ADHD in Swedish adults over time, and assessed comorbidities and pharmacologic treatment. Methods: National Patient Register data were used to estimate the overall prevalence of adults (≥18 years) with a registered ADHD diagnosis from 2006 to 2011, and the incidence of newly registered diagnoses from 2007 to 2011...
2018: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29765218/the-effects-of-maras-powder-use-on-patients-with-migraine
#8
Yılmaz İnanç, Fatma Özlem Orhan, Yusuf İnanç
Background: It is accepted that smoking often triggers migraine. However, studies evaluating the relationship between the use of smokeless tobacco and migraine are limited, and there is no clear consensus on the subject. In this study, it was aimed to evaluate the relationship between migraine and Maras powder, which is the most common smokeless tobacco in Turkey. Subjects and methods: The study included a total of 600 subjects, consisting of 300 patients (aged >18 years) diagnosed with a migraine according to the International Headache Society (IHS-ICHD-3 Beta) criteria after presenting at Sütçü Imam University Medical Faculty Neurology Policlinic with the complaint of headache between July 2016 and December 2016 and a control group of 300 individuals with similar features of age, gender, and educational level...
2018: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29765217/allergy-to-chlorpromazine-and-valproic-acid-following-carbamazepine-hypersensitivity-in-a-patient-with-an-hla-b-4601-allele
#9
Kumi Sakurada, Takeshi Kozaru, Kazuo Yamada, Masashi Nibuya, Kiyoshi Nagata, Eiji Suzuki
A 73-year-old man, exhibiting psychomotor excitement after traumatic brain injury, developed allergic cutaneous eruptions and hepatic inflammation that did not resolve after the cessation of carbamazepine (CBZ). Fusing maculopapular erythema was observed in the face, neck, presternal region, and bilaterally in the forearms and feet. A drug-induced lymphocyte stimulation test revealed hypersensitivity to chlorpromazine (CPZ) and valproic acid (VPA), as well as to CBZ. The allergic reaction with eosinophilia to CPZ and VPA was suspected to have emerged following CBZ hypersensitivity, since previous treatment with CPZ and VPA prior to the introduction of CBZ had not been associated with adverse reactions earlier in the course of treatment...
2018: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29750035/antidepressant-medication-use-and-nasopharyngeal-cancer-risk-a-nationwide-population-based-study
#10
Chiao-Fan Lin, Hsiang-Lin Chan, Yi-Hsuan Hsieh, Hsin-Yi Liang, Wei-Che Chiu, Yena Lee, Roger S McIntyre, Vincent Chin-Hung Chen
Background: The association between antidepressant exposure and nasopharyngeal cancer (NPC) has not been previously explored. The purpose of this study was to investigate the association between antidepressant prescription, including novel antidepressants, and the risk of NPC in a population-based study. Materials and methods: Data for the analysis were derived from National Health Insurance Research Database. We identified 16,957 cases with a diagnosis of NPC and 83,231 matched controls by using a nested case-control design...
2018: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29731635/antidopaminergic-medication-in-healthy-subjects-provokes-subjective-and-objective-mental-impairments-tightly-correlated-with-perturbation-of-biogenic-monoamine-metabolism-and-prolactin-secretion
#11
Tanja Veselinović, Ingo Vernaleken, Paul Cumming, Uwe Henning, Lina Winkler, Peter Kaleta, Michael Paulzen, Christian Luckhaus, Gerhard Gründer
Objectives: Off-label prescription of antipsychotics to patients without psychotic symptoms has become a routine matter for many psychiatrists and also some general practitioners. Nonetheless, little is known about the possibly detrimental effects of antidopaminergic medications on general psychopathology, subjective mental state, or a possible association with physiological parameters in nonpsychotic individuals. Methods: In this randomized, single-blinded study, groups of healthy volunteers (n=18) received low doses of reserpine, aripiprazole, haloperidol, or placebo on 7 successive days...
2018: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29731634/long-term-quality-of-life-in-cervical-dystonia-after-treatment-with-abobotulinum-toxin-a-a-2-year-prospective-study
#12
Subsai Kongsaengdao, Narong Maneeton, Benchalak Maneeton
Background: The short-term quality of life (QoL) in cervical dystonia (CD) after treating with abobotulinum toxin A (Abo-BTX A) and neubotulinum toxin A (Neu-BTX A) have been studied in Thai CD patients. However; the long-term study has not been published. Objective: The aim of the present study was to determine long-term improvement of the health-related quality of life (HRQoL) after eight injections of Abo-BTX A over 2 years in CD patients. Patients and methods: A 2-year prospective study on the QoL of CD patients, as measured by HRQoL, before and after receiving eight injections of Abo-BTX A at 3-month intervals over a 2-year treatment period was performed...
2018: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29731633/impact-of-time-of-initiation-of-once-monthly-paliperidone-palmitate-in-hospitalized-asian-patients-with-acute-exacerbation-of-schizophrenia-a-post-hoc-analysis-from-the-prevail-study
#13
Huafang Li, Yan Li, Yu Feng, Jianmin Zhuo, Ibrahim Turkoz, Maju Mathews, Wilson Tan
Purpose: To evaluate the differences in efficacy and safety outcomes in acute exacerbating schizophrenia patients between 2 subgroups (≤1 week and >1 week), differing in time interval from hospitalization to time of initiation of once-monthly paliperidone palmitate. Patients and methods: PREVAIL was a multicenter, single-arm, open-label, prospective Phase IV study in hospitalized Asian patients (either sex, aged 18-65 years) diagnosed with schizophrenia ( Diagnostic and Statistical Manual of Mental Disorders , Fourth Edition)...
2018: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29722366/erratum-prospective-interepisodal-mood-monitoring-in-patients-with-affective-disorders-a-feasibility-study-corrigendum
#14
(no author information available yet)
[This corrects the article on p. 517 in vol. 14, PMID: 29491711.].
2018: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29719400/new-horizons-for-multiple-sclerosis-therapeutics-milestones-in-the-development-of-ocrelizumab
#15
REVIEW
Jessica Frau, Giancarlo Coghe, Lorena Lorefice, Giuseppe Fenu, Eleonora Cocco
Multiple Sclerosis (MS) is an inflammatory and neurodegenerative disease of the central nervous system, and both T and B cells are involved in its pathogenesis. The vast majority of disease-modifying drugs used for MS act on the inflammatory component of the disease and are approved for use in relapsing-remitting (RR) patients. Ocrelizumab (OCR) is the only MS drug that has been approved by the US Food and Drug Administration (FDA) not only for patients with RRMS but also for patients with primary progressive (PP) MS...
2018: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29719399/effectiveness-and-safety-of-oral-olanzapine-treatment-transitioned-from-rapid-acting-intramuscular-olanzapine-for-agitation-associated-with-schizophrenia
#16
Hideaki Katagiri, Masanori Taketsuna, Shinpei Kondo, Kenta Kajimoto, Etsuko Aoi, Yuka Tanji
Objective: To assess the effectiveness and safety of oral olanzapine treatment transitioned from rapid-acting intramuscular olanzapine (RAIM) in patients with acute agitation associated with schizophrenia in a real-world clinical setting. Methods: The postmarketing surveillance study with a 3-day observational period after the last RAIM administration was conducted (original study). Following this, an extended study was added for patients who received oral olanzapine after RAIM administration during the original study period, in order to additionally observe them for 7 days after initial RAIM administration...
2018: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29719398/comparison-of-changes-in-oxygenated-hemoglobin-during-the-tree-drawing-task-between-patients-with-schizophrenia-and-healthy-controls
#17
Shinya Nakano, Yoshihisa Shoji, Kiichiro Morita, Hiroyasu Igimi, Mamoru Sato, Youhei Ishii, Akihiko Kondo, Naohisa Uchimura
Background: Tree-drawing test is used as a projective psychological test that expresses the abnormal internal experience in patients with schizophrenia (SZ). Despite the widely accepted view that the cognitive function is involved in characteristic tree-drawing in patients with SZ, no study has psychophysiologically examined it. The present study aimed to investigate the involvement of cognitive function during tree-drawing in patients with SZ. For that purpose, we evaluated the brain function in patients with SZ during a tree-drawing task by using near-infrared spectroscopy (NIRS) and compared them with those in healthy controls...
2018: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29713176/aberrant-brain-functional-connectome-in-patients-with-obstructive-sleep-apnea
#18
Li-Ting Chen, Xiao-Le Fan, Hai-Jun Li, Cheng-Long Ye, Hong-Hui Yu, Hui-Zhen Xin, Hong-Han Gong, De-Chang Peng, Li-Ping Yan
Objective: Obstructive sleep apnea (OSA) is accompanied by widespread abnormal spontaneous regional activity related to cognitive deficits. However, little is known about the topological properties of the functional brain connectome of patients with OSA. This study aimed to use the graph theory approaches to investigate the topological properties and functional connectivity (FC) of the functional connectome in patients with OSA, based on resting-state functional magnetic resonance imaging (rs-fMRI)...
2018: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29713175/electroconvulsive-therapy-in-77-year-old-patient-with-pacemaker-a-case-report
#19
Tomasz Mędrala, Anna Pycińska, Bartłomiej Pyciński, Wojciech Merk, Krzysztof Kucia
The treatment of a 77-year-old patient suffering from severe psychotic depression with a cardiac pacemaker is described. Because of treatment-resistant depression, electroconvulsive therapy (ECT) was introduced. In the course of ECT, there was a great improvement in his mental state without any cardiac complications. This case may be evidence for the safety and effectiveness of ECT in the elderly, even with cardiac comorbidities. Some recommendations for ECT in patients with pacemakers are discussed.
2018: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29713174/reac-neuromodulation-treatments-in-subjects-with-severe-socioeconomic-and-cultural-hardship-in-the-brazilian-state-of-par%C3%A3-a-family-observational-pilot-study
#20
José Alfredo Coelho Pereira, Arianna Rinaldi, Vania Fontani, Salvatore Rinaldi
Purpose: The purpose of this preliminary observational study was to evaluate the usefulness of a humanitarian initiative, aimed at improving the neuropsychological and behavioral attitude of children with severe socioeconomic and cultural hardship, in the Brazilian state of Pará. This humanitarian initiative was realized through the administration of two neuromodulation protocols, with radioelectric asymmetric conveyor (REAC) technology. During several years of clinical use, the REAC neuromodulation protocols have already proved to be effective in countering the effects of environmental stress on neuropsycho-physical functions...
2018: Neuropsychiatric Disease and Treatment
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