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Future Cardiology

Umair Khalid, Hani Jneid, Ali Emin Denktas
No abstract text is available yet for this article.
May 16, 2018: Future Cardiology
Carmine Muto, Francesco Solimene, Vincenzo Russo, Gerardo Nigro, Anna Rago, Raffaele Chianese, Paola Chiariello, Carmine Ciardiello, Luigi Caliendo
AIM: To evaluate at a 12-month follow-up, the clinical and echocardiographic outcomes in postmyocardial infarction (MI) heart failure patients who underwent cardiac resynchronization therapy (CRT) device implantation. MATERIALS & METHODS: A total of 100 patients received a CRT device, and the study population was divided into three groups, according to the site of MI and left ventricular (LV) lead placed downstream of the ischemic area, as evaluated by echocardiography...
May 16, 2018: Future Cardiology
Alexandra Ai Abel
The 20th Annual Autumn Meeting of the British Society for Heart Failure took place on the 23-24 November 2017 at the Queen Elizabeth II Conference Centre, London, UK. Over 800 delegates were in attendance: a multidisciplinary league of professionals who treat patients with heart failure, including specialist nurses, trainees, cardiologists, geriatricians, pharmacists and general practitioners. The theme of the conference was 'three decades of heart failure' and celebrated the success of modern heart failure management...
May 16, 2018: Future Cardiology
Stefan Müller-Hülsbeck, Silke Hopf-Jensen, Koen Keirse, Thomas Zeller, Herman Schroë, Juan Diaz-Cartelle, William A Gray
Endovascular options are increasingly recognized as primary treatments for lower extremity peripheral arterial disease inadequately responsive to noninvasive therapy. Options include balloon angioplasty and stent implantation, and newer technologies incorporate drug coatings to prevent restenosis and reduce the need for reintervention. The Eluvia drug-eluting vascular stent system (Boston Scientific, MA, USA) was designed with a biocompatible fluoropolymer coating to allow for drug elution over time. Initial clinical results demonstrate promising efficacy in terms of sustained femoropopliteal artery patency along with a good safety profile...
April 10, 2018: Future Cardiology
Hiroyoshi Mori, Hiroyuki Jinnouchi, Chahal Diljon, Sho Torii, Atsushi Sakamoto, Frank D Kolodgie, Renu Virmani, Aloke V Finn
The COBRA-PzF™ (CeloNova BioSciences, Inc., TX, USA) is a new type of coronary stent composed of a cobalt chromium metallic backbone surrounded by a nanothin layer of Polyzene-F (PzF) without any added drug. Evidence from basic studies supports antithrombotic and anti-inflammatory properties for the PzF surface coating. Preclinical studies support the thromboresistance of PzF coated surfaces and clinical studies have shown good outcomes for patients receiving this device with very low rates of stent thrombosis...
March 27, 2018: Future Cardiology
Robert J Henning
One out of every two men and one out of every three women greater than the age of 40 will experience an acute myocardial infarction (AMI) at some time during their lifetime. As more patients survive their AMIs, the incidence of congestive heart failure (CHF) is increasing. 6 million people in the USA have ischemic cardiomyopathies and CHF. The search for new and innovative treatments for patients with AMI and CHF has led to investigations and use of human embryonic stem cells, cardiac stem/progenitor cells, bone marrow-derived mononuclear cells and mesenchymal stem cells for treatment of these heart conditions...
March 2018: Future Cardiology
Azadeh Shohoudi, David A Stephens, Paul Khairy
Escalating costs of cardiovascular trials are limiting medical innovations, prompting the development of more efficient and flexible study designs. The Bayesian paradigm offers a framework conducive to adaptive trial methodologies and is well suited for the study of small populations. Bayesian adaptive trials provide a statistical structure for combining prior information with accumulating data to compute probabilities of unknown quantities of interest. Adaptive design features are useful in modifying randomization schemes, adjusting sample sizes and providing continuous surveillance to guide decisions on dropping study arms or premature trial interruption...
March 2018: Future Cardiology
Nandhinee Radha Shanmugam, Sriram Muthukumar, Ambalika Sanjeev Tanak, Shalini Prasad
AIM: Development of a label-free multiplexed point-of-care diagnostic device for a panel of cardiac biomarkers - cardiac troponin-T (cTnT), troponin-I (cTnI) and B-type natriuretic peptide (BNP). METHODS: A nonfaradaic electrochemical immunoassay designed with anisotropic high surface area ZnO nanostructures grown using low-temperature hydrothermal methods was selectively immobilized with capture antibodies. Multiplexed detection in human serum using ZnO nanostructures based on complementary electrochemical measurement techniques - electrochemical impedance spectroscopy and Mott-Schottky...
March 2018: Future Cardiology
Mostafa Elwany, Gaetano Di Palma, Bernardo Cortese
Coronary lesions at bifurcation sites are frequent and still remain a challenging subset for the interventional cardiologist. Although in the last years the provisional stenting technique has shown more consistent results, coronary bifurcation interventions still share a worse procedural success rate and increased rates of mid- and long-term cardiac events. Most of the dedicated devices proposed in the last few years have failed to show improved results when compared with standard devices. The broader use of imaging techniques, such as intravascular ultrasound and optical coherence tomography, lead to a better understanding of the real anatomy of bifurcations and has shown to be a great tool for percutaneous coronary intervention optimization...
March 2018: Future Cardiology
Atul Gupta
Atul Gupta, MD speaks to Adam Price-Evans, Managing Commissioning Editor of Future Cardiology. Atul Gupta is the Global Chief Medical Officer for the business group Image Guided Therapy at Philips, providing medical guidance to Philips' clinical vision and strategy. As a practicing interventional and diagnostic radiologist, he also serves as a key external clinical voice for Image Guided Therapy. His key responsibilities include supporting innovation and product development in cardiology, peripheral vascular, surgical, oncology interventions, clinical education, office-based labs, medical affairs and new business development and ventures...
March 2018: Future Cardiology
Bruno Bordoni, Fabiola Marelli, Bruno Morabito, Beatrice Sacconi
No abstract text is available yet for this article.
March 2018: Future Cardiology
Diana Glovaci, Ali Naqvi, Katherine Yu, Pranav Patel, Mayil Krishnam
AIM: Postmyocardial infarction ventricular septal defect (VSD) is a rare complication that can lead to rapid hemodynamic patient decompensation. The type of VSD repair relies on several factors including: size, location, timing and surgical expertise. CASE: A 63-year-old man with a ST-elevation myocardial infarction underwent percutaneous coronary intervention of the right coronary artery. A holosystolic murmur was notable postcatheterization, and transthoracic echocardiogram confirmed a VSD...
March 2018: Future Cardiology
Juan Tang, Kathy O Lui, Bin Zhou
No abstract text is available yet for this article.
March 2018: Future Cardiology
Alexander N Kharlamov, Ilya V Zubarev, Ekaterina V Shishkina, Vladimir Ya Shur
No abstract text is available yet for this article.
March 2018: Future Cardiology
Gulten Tacoy
No abstract text is available yet for this article.
March 2018: Future Cardiology
Panagiota Anna Chousou, Peter J Pugh
A substantial proportion of patients who undergo cardiac device implantation receive oral anticoagulation to prevent thromboembolism or antiplatelets to prevent thrombotic events. Anticoagulation and antiplatelets increase the risk of hemorrhagic complications, while discontinuation may increase thromboembolic risk and thrombotic events. With the introduction of non-vitamin K antagonist oral anticoagulant agents and the newer antiplatelet agents such as prasugrel or ticagrelor, the perioperative management of patients has become more challenging...
March 2018: Future Cardiology
Jesse X Yang, Robert W Yeh
Drug-eluting stents revolutionized the treatment of coronary artery disease with vastly improved outcomes compared with bare metal stents. As stent technology has evolved, a wide variety of antiproliferative drugs have been developed to prevent stent restenosis and stent thrombosis. The Resolute stent system (Medtronic, CA, USA) elutes zotarolimus from a multipolymer blend to prevent early and late stent-related complications. The Resolute stents have evolved from the initial Resolute stent, to the Resolute Integrity™ and most recently, the Resolute Onyx™...
February 16, 2018: Future Cardiology
Rui Shi, Mark Norman, Zhong Chen, Tom Wong
Atrial fibrillation (AF) is the most common clinical arrhythmia encountered. Catheter ablation has become the first-line therapy for symptomatic drug-refractory paroxysmal and persistent AF. Although pulmonary vein electrical isolation is still the cornerstone of the ablation strategy, the clinical outcome particularly in treating persistent AF is suboptimal. Significant efforts have been applied with live global chamber mapping of AF aimed to identify patient-specific drivers and/or maintainers located outside of the pulmonary veins to further improve the outcome of catheter ablation...
February 14, 2018: Future Cardiology
Carol Chen-Scarabelli, William G Hundley, Tiziano M Scarabelli
No abstract text is available yet for this article.
January 22, 2018: Future Cardiology
Anna Jacobs, Rajesh Kabra, Pranab Das, Carrie S Oliphant
Following publication of our review article 4 years ago, there has been an uptake in the use of nonvitamin K oral antagonists, also known as direct oral anticoagulants. The most recent Xa inhibitors to receive approval are edoxaban, which has been approved for use in both atrial fibrillation and venous thromboembolism prevention and betrixaban, which has been approved in the USA for extended thromboprophylaxis in the medically ill population. Additional analyses of certain types of atrial fibrillation patients have now become available...
January 2018: Future Cardiology
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