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Cardiovascular Revascularization Medicine: Including Molecular Interventions

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https://www.readbyqxmd.com/read/28684062/intracoronary-high-dose-bolus-tirofiban-administration-during-complex-coronary-interventions-a-united-states-based-case-series
#1
Charles I Wilmer
The GP IIb/IIIa inhibitors (GPIs) rapidly provide therapeutic levels of platelet aggregation inhibition and serve as adjunct pharmacotherapy to oral P2Y12 inhibitors that exhibit a significant delay in onset of action for patients with Acute Coronary Syndrome (ACS). Intracoronary (IC) administration of the high dose bolus (HDB) tirofiban has not been extensively studied. Compared to intravenous delivery, IC administration can lead to higher local drug concentration and, therefore, provide instantaneous disruption of platelet aggregation in the culprit vessel...
June 22, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28651834/the-impact-of-care-management-information-technology-model-on-quality-of-care-after-coronary-artery-bypass-surgery-bridging-the-divides
#2
William S Weintraub, Daniel Elliott, Zaher Fanari, Jennifer Ostertag-Stretch, Ann Muther, Margaret Lynahan, Roger Kerzner, Tabassum Salam, Herbert Scherrer, Sharon Anderson, Carla A Russo, Paul Kolm, Terri H Steinberg
BACKGROUND: Reducing readmissions and improving metrics of care are a national priority. Supplementing traditional care with care management may improve outcomes. The Bridges program was an initial evaluation of a care management platform (CareLinkHub), supported by information technology (IT) developed to improve the quality and transition of care from hospital to home after Coronary Artery Bypass Surgery (CABG) and reduce readmissions. METHODS: CareLink is comprised of care managers, patient navigators, pharmacists and physicians...
June 21, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28666791/assessing-the-left-main-stem-in-the-cardiac-catheterization-laboratory-what-is-significant-function-imaging-or-both
#3
REVIEW
George Kassimis, Giovanni Luigi de Maria, Niket Patel, Raina Tushar, Peter Scott, Rajesh K Kharbanda, Adrian P Banning
Revascularization of significant Left Main Stem (LMS) disease improves clinical outcomes. This can be achieved through either Coronary Artery Bypass Grafting or Percutaneous coronary intervention. Defining a significant stenosis of the LMS can be challenging and debatable, as most data have been derived using angiographic assessment alone, with a threshold of 50% luminal stenosis used as a marker of functional significance. The use of adjunctive technologies like Intravascular Ultrasound and Fractional Flow Reserve has improved our ability to accurately assess the anatomical severity and physiological significance of coronary artery stenoses, much more so, than can be achieved through conventional angiography alone...
June 20, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28648324/drug-coated-balloon-angioplasty-for-the-management-of-recurring-infrapopliteal-disease-in-diabetic-patients-with-critical-limb-ischemia
#4
Luis M Palena, Larry J Diaz-Sandoval, Efren Gòmez Jabalera, Olga Peypoch Perez, Enrico Sultato, Cesare Brigato, Enrico Brocco, Marco Manzi
OBJECTIVE: To describe the 1-year outcomes of recurring infrapopliteal disease after endovascular revascularization with the Lutonix drug-coated balloons (LDCB) in diabetic patients with critical limb ischemia (CLI), and to benchmark our findings with previously published objective performance goals (OPG) addressing safety and efficacy of new catheter-based therapies for CLI. METHODS: The present study was a retrospective, single-center, and single-arm trial of symptomatic diabetic patients with CLI, who underwent LDCB-angioplasty for recurring infrapopliteal disease...
June 20, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28606787/bermuda-triangle-chronic-kidney-disease-contrast-induced-nephropathy-and-atrial-fibrillation
#5
LETTER
Levent Cerit
No abstract text is available yet for this article.
June 9, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28624360/association-between-arterial-access-site-and-anticoagulation-strategy-on-major-bleeding-and-mortality-a-historical-cohort-analysis-in-the-veteran-population
#6
Jayant Bagai, Bert Little, Subhash Banerjee
BACKGROUND: Studies have shown reduction in major bleeding with trans-radial intervention (TRI) compared with trans-femoral intervention (TFI), and with use of bivalirudin compared with heparin+glycoprotein IIb/IIIa inhibitors (GPI). We compared major bleeding, mortality and the interaction between arterial access site and the anticoagulant used for PCI in Veterans. METHODS: A retrospective cohort of 1192 consecutive patients who underwent PCI at a VA hospital between 2006 and 2012 was divided into TFI-heparin (n=192), TFI-bivalirudin (n=272), TRI-heparin (n=274) and TRI-bivalirudin (n=454) groups...
June 8, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28606788/coronary-bifurcation-model-created-using-a-novel-directional-heat-injury-catheter
#7
Kenji Nakatsuma, Shin Watanabe, Akihiro Tokushige, Erika Yamamoto, Bingyuan Bao, Hiroki Watanabe, Takeshi Kimura, Naritatsu Saito
OBJECTIVES: The present study aimed to develop a swine coronary bifurcation model. BACKGROUND: In human coronary bifurcation lesion, atherosclerotic plaques are usually observed in the lateral wall, whereas the flow divider regions are spared. There is currently no suitable coronary bifurcation animal model, on which a new stent can be tested. METHODS: We developed a novel directional heat injury catheter, which comprised of a non-compliant balloon catheter (diameter: 3...
June 7, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28610773/contrast-induced-acute-kidney-injury-in-interventional-cardiology-emerging-evidence-and-unifying-mechanisms-of-protection-by-remote-ischemic-conditioning
#8
REVIEW
Adebayo C Atanda, Oladipupo Olafiranye
Contrast-induced acute kidney injury (CI-AKI) is a common complication of many diagnostic and therapeutic cardiovascular procedures. It is associated with longer in-hospital stay, more complicated hospitalization course, and higher in-hospital morbidity and mortality. With increasing use of contrast media in various diagnostic and interventional procedures, the prevalence of CI-AKI is expected to rise. Although pre-hydration with intravenous normal saline is recommended in patients with elevated risk of CI-AKI, this approach is often not feasible in many clinical settings...
June 6, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28600019/safety-and-efficacy-outcomes-of-second-generation-everolimus-eluting-stents-in-octogenarians-compared-to-non-octogenarians
#9
Hironori Kitabata, Takashi Kubo, Kazuya Mori, Yasunori Yamamoto, Manabu Kashiwagi, Yu Arita, Takashi Tanimoto, Takashi Akasaka
BACKGROUND: In patients ≥80 years of age, the use of second-generation cobalt-chromium everolimus-eluting stents (CoCr-EES) versus bare-metal stents has been shown to reduce myocardial infarction (MI) and target vessel revascularization (TVR) rates, without an increase in bleeding. However, safety and efficacy of CoCr-EES in octogenarians compared to younger populations are less certain. We aimed to compare the clinical outcomes between octogenarian and non-octogenarian patients undergoing percutaneous coronary intervention (PCI) with CoCr-EES...
June 1, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28625402/comparison-between-catheter-based-delivery-of-paclitaxel-after-bare-metal-stenting-and-drug-eluting-stents-in-coronary-artery-disease-patients-at-high-risk-for-in-stent-restenosis
#10
Mostafa El-Mokadem, Mohamed El-Ramly, Amr Hassan, Hesham Boshra, Amir AbdelWahab
BACKGROUND: Drug eluting stents reduce the risk of in-stent restenosis but delay healing of the vascular wall. Recent data on late and very late stent thrombosis after drug-eluting stent (DES) implantation have raised concerns about the long-term safety. High lipophilicity of paclitaxel promotes rapid cellular uptake and prolongs its action. This makes paclitaxel a very promising candidate for local drug therapy intended to inhibit the proliferative and migratory processes involved in restenosis following PCI...
May 31, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28602575/here-we-go-again-trying-to-prevent-contrast-induced-nephropathy
#11
Fabio V Lima, Luis Gruberg
No abstract text is available yet for this article.
May 31, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28600021/st-segment-elevation-myocardial-infarction-in-patients-hospitalized-for-non-cardiac-conditions
#12
Justin Tiulim, Kevin Mak, David M Shavelle
BACKGROUND: Timely use of primary percutaneous coronary intervention (PCI) is the standard of care for patients with ST segment elevation myocardial infarction (STEMI). Most patients with STEMI present via emergency medical services or self-transport to the emergency department (ED) and relatively little is known about the minority of patients that develop STEMI while hospitalized for non-cardiac conditions. The objective of this study was to analyze treatment times and clinical outcome for in-hospital STEMI patients...
May 31, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28595810/successful-percutaneous-retrieval-of-embolized-transcatheter-left-atrial-appendage-closure-device-watchman-using-a-modified-vascular-retrieval-forceps
#13
Zaher Fanari, Sachin Goel, Jeffrey A Goldstein
Transcatheter closure of the left atrial appendage (LAA) is increasingly considered as an alternative to oral anticoagulation in patients with previous major bleeding or at high-risk of bleeding. Device embolization with transcatheter LAA closure is a rare complication. Most cases are asymptomatic, but it can be life threatening. Depending on the location of embolization, percutaneous retrieval is feasible. Snares are usually used for retrieval, but other devices may be used. We report the case of a 63-year gentleman who underwent an uneventful LAA closure with Watchman device and routine testing next day showed embolization to the abdominal aorta...
May 31, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28578897/inadvertent-anastomosis-of-the-left-internal-mammary-artery-to-the-great-cardiac-vein
#14
Shahryar G Saba, John N Makaryus, Shoshanah Kahn, Rakesh Shah, Perwaiz Meraj
We present an uncommon and underreported complication of coronary artery bypass graft surgery: erroneous anastomosis of the left internal mammary artery to the great cardiac vein. The iatrogenic aorto-coronary arteriovenous fistula with left-to-right shunting resulted in dilation of the coronary sinus, a supporting secondary finding. Factors predisposing to this inadvertent anastomosis include an intramyocardial segment of the left anterior descending coronary artery, demonstrated in this case, as well as epicardial fat and potentially fibrosis of the underlying myocardium...
May 19, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28551423/safety-and-predictors-of-next-day-discharge-after-elective-transfemoral-transcatheter-aortic-valve-replacement
#15
Sulaiman Rathore, Yevgeniy Latyshev, Sheree Emore, Joseph Rowe, Jason Foerst
OBJECTIVES: We sought to determine the predictors of next-day discharge (NDD) for selected patients undergoing elective transfemoral transcatheter aortic valve replacement (TF-TAVR). BACKGROUND: Techniques have rapidly evolved over the last several years to simplify TF-TAVR allowing for a subset of patients to be discharged the next day. METHODS: Baseline and procedural characteristics, in-hospital and 30-day follow-up outcomes, complications and readmission rates of 100 TF-TAVR cases were assessed...
May 19, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28552503/tavr-and-renal-function-a-love-and-hate-story
#16
Saar Minha, Israel M Barbash
No abstract text is available yet for this article.
May 18, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28551422/utility-of-a-0-035%C3%A2-compatible-rapid-exchange-balloon-metacross-rx%C3%A2-as-a-perfusion-balloon-in-endovascular-therapy-compared-with-conventional-percutaneous-coronary-intervention-a-mini-review
#17
REVIEW
Keisuke Nakabayashi, Nobuhito Kaneko, Daisuke Sunaga, Akihiro Matsui, Kazuhiko Tanaka, Hiroshi Ando, Minoru Shimizu
Since endovascular treatment for peripheral artery disease has been rapidly and widely adopted as the preferred strategy, interventionists sometimes experience complications such as vessel perforation and severe dissections. We have a long-time inflation strategy for perfusion balloon catheters, which could be a solution for vessel complications in coronary sections, but not in peripheral sections. We invented a simple device for application as a perfusion balloon in peripheral sections, using a 0.035″ wire compatible rapid-exchange balloon Metacross RX™ (TERUMO, Tokyo, Japan) and reviewed this strategy using three cases as examples and compared them with the coronary perfusion balloon...
May 18, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28546035/hybrid-metal-scaffold-jacket-versus-full-metal-jackets-in-left-anterior-descending-coronary-artery-diffuse-disease-differences-in-radiation-exposure-and-fluoroscopic-procedural-times
#18
Gianluca Rigatelli, Marco Zuin, Jacopo Frigato, Fabio Dell'Avvocata, Federico Ronco, Alberto Mazza, Laura Oliva, Dario Adami, Emiliano Bedendo, Panin Stefano
BACKGROUND/PURPOSE: Bioabsorbable vascular scaffolds (BVS) are made from a radiolucent material. Their multiple implantations on a single long diffused segment requires a specific technique with imaging magnification, which could cause an increase in dose delivered during percutaneous coronary intervention (PCI) procedure. We aimed to identify differences in radiation dose, fluoroscopy and procedural times in Hybrid DES+ multiple BVS (Absorb, Abbott Inc., USA) implantation (hybrid metal/scaffold jacket) versus multiple III generation Drug-eluting stents (DES) (full-metal jacket) in patients with long and diffuse coronary artery disease of the left anterior descending (LAD) coronary artery...
May 18, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28546034/in-stent-restenosis-nine-years-after-initial-placement-of-a-drug-eluting-stent
#19
Dennis A Hopkinson, Vikram Raje, Ion S Jovin
In-stent restenosis after drug-eluting stent implantation is a rare event and the time frame of restenosis occurrence is less well understood for drug-eluting stent. We describe the case of a patient who presented with an acute coronary syndrome and was found to have severe focal in-stent restenosis in a drug-eluting stent that was placed 9 years earlier.
May 18, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28539211/left-ventricular-perforation-in-a-patient-with-a-left-ventricular-aneurysm-during-noga%C3%A2-catheter-mapping
#20
Gaurav K Sharma, Marie-France Poulin, Gary L Schaer
Endocardial mapping of the left ventricle (LV) using the NOGA® XP Cardiac Navigation System can identify chronically ischemic and viable myocardium in patients with coronary artery disease by generating electromechanical maps. These maps are very useful when targeting myocardial tissue for injection of stem cells. We present the case of a woman who developed a perforation at the site of an LV aneurysm during NOGA mapping prior to the transendocardial injection of stem cells, as part of a multicenter clinical trial...
May 13, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
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