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Cardiovascular Revascularization Medicine: Including Molecular Interventions

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https://www.readbyqxmd.com/read/30415970/approaching-the-post-femoral-era-for-coronary-angiography-and-intervention
#1
EDITORIAL
Sasko Kedev
No abstract text is available yet for this article.
November 9, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/30447898/endovascular-management-of-femoropopliteal-in-stent-restenosis-a-systematic-review
#2
REVIEW
Daniel L Varela, Ehrin J Armstrong
Despite the development of new therapies for the treatment of femoropopliteal disease, nitinol stents remain a mainstay of therapy following balloon angioplasty. Consequently, femoropopliteal in-stent restenosis (FP-ISR) remains an important clinical problem. Interventions used to treat de novo lesions of the femoropopliteal segment have been used to treat ISR lesions, with disappointing outcomes. Early interventions focused on repeat balloon angioplasty, cryoplasty, and various debulking therapies. Recently, treatment has shifted towards the use of stent-grafts, drug-eluting therapies, and combination therapies...
November 7, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/30446399/plasma-epinephrine-levels-and-its-causal-link-to-takotsubo-syndrome-revisited-critical-review-with-a-diverse-conclusion
#3
REVIEW
Shams Y-Hassan
Takotsubo syndrome (TS) is a recognized acute cardiac syndrome with a clinical presentation resembling that of an acute coronary syndrome (ACS). The defining feature of TS is the reversible left ventricular wall motion abnormality (LVWMA), which has a unique circumferential pattern resulting in a conspicuous ballooning of the left ventricle during systole, and extending beyond the coronary artery supply territory. The pathogenesis of TS is still elusive and several pathophysiological mechanisms have been proposed...
November 7, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/30446398/drug-eluting-versus-bare-metal-stents-in-older-patients-a-meta-analysis-of-randomized-controlled-trials
#4
Babikir Kheiri, Mohammed Osman, Ahmed Abdalla, Tarek Haykal, Adam Chahine, Meghan Gwinn, Sahar Ahmed, Mustafa Hassan, Ghassan Bachuwa, Deepak L Bhatt
BACKGROUND: Despite the high prevalence of ischemic heart disease in older patients, there is a substantial lack of evidence to guide clinical decision-making in this population. Hence, we performed a meta-analysis to determine the safety and efficacy of percutaneous coronary intervention (PCI) with drug-eluting stents (DES) versus bare-metal stents (BMS). METHODS: Electronic databases were searched for randomized trials comparing DES with BMS in patients ≥70 years-old...
November 7, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/30442536/clinical-outcomes-one-year-and-beyond-after-combination-sirolimus-eluting-endothelial-progenitor-cell-capture-stenting-during-primary-percutaneous-coronary-intervention-in-st-segment-elevation-myocardial-infarction
#5
Hui Wen Sim, Elizabeth H Thong, Huay Cheem Tan, Adrian F Low, Chi-Hang Lee, Mark Y Chan, Edgar L Tay, Poay Huan Loh, Koo Hui Chan, Joshua P Loh
BACKGROUND/PURPOSE: Primary percutaneous coronary intervention (PCI) during acute ST-segment elevation myocardial infarction (STEMI) represents a thrombotic milieu and is associated with delayed healing after stenting. The pro-healing combination sirolimus eluting endothelial progenitor cell (EPC) capture stents encourage early endothelialization after stenting and may be beneficial in the STEMI population. We aim to evaluate the clinical outcomes one year and beyond for patients with STEMI who received the combination sirolimus eluting EPC capture stents during primary PCI...
November 7, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/30442537/transradial-versus-transfemoral-access-for-percutaneous-coronary-intervention-of-unprotected-left-main-coronary-artery-stenosis-a-systematic-review-and-meta-analysis
#6
Anurag Bajaj, Samir Pancholy, Arpit Sothwal, Yassir Nawaz, Pranjal Boruah
INTRODUCTION: PCI of ULMS is frequently performed through TFA because of technical complexity and safety concern. Studies have shown comparable efficacy and safety of TRA versus TFA, however, these studies are few in number. We intended to compare the clinical outcomes between transradial access (TRA) and transfemoral access (TFA) in patients undergoing percutaneous coronary intervention (PCI) for unprotected left main coronary artery stenosis (ULMS) by performing a meta-analysis. METHOD: A systematic search of database, including, PubMed, Web of Science, Google scholar and Cochrane Database were performed by two independent reviewers...
November 3, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/30420279/validation-of-a-novel-system-for-co-registration-of-coronary-angiographic-and-intravascular-ultrasound-imaging
#7
Khalil Houissa, Nicola Ryan, Javier Escaned, Nick L Cruden, Neal Uren, Tristan Slots, Peter Kayaert, Stéphane G Carlier
INTRODUCTION: Intravascular ultrasound (IVUS) is a useful adjunct to guide percutaneous coronary intervention (PCI). Correlating IVUS images with angiographic findings can be challenging. We evaluated the utility of a novel co-registration system for IVUS and coronary angiography. METHODS AND RESULTS: A 3-D virtual catheter trajectory was constructed from separate angiographic imaging runs using bespoke software. Intravascular ultrasound images were obtained using a commercially available mechanical rotational transducer with motorized pullback...
November 3, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/30414797/effect-of-intravascular-cooling-on-microvascular-obstruction-mvo-in-conscious-patients-with-st-elevation-myocardial-infarction-undergoing-primary-pci-results-from-the-cool-ami-eu-pilot-study
#8
Thomas R Keeble, Grigoris V Karamasis, Marco Noc, Beata Sredniawa, Daniel Aradi, Aleksandar N Neskovic, Håkan Arheden, David Erlinge, Michael Holzer
OBJECTIVE: COOL AMI EU pilot was a multi-center, randomized controlled trial to assess feasibility and safety of rapid intravascular therapeutic hypothermia (TH) in conscious patients with anterior ST-elevation myocardial infarction (STEMI) undergoing primary PCI (PPCI). We report the effect of hypothermia upon microvascular obstruction (MVO). METHODS: Conscious patients with anterior STEMI and symptom duration <6 h were recruited and randomized to PPCI + TH or PPCI alone...
October 29, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/30409500/combined-rotational-atherectomy-and-intravascular-lithotripsy-for-the-treatment-of-severely-calcified-in-stent-neoatherosclerosis-a-mini-review
#9
REVIEW
Guozhu Chen, Bernhard Zrenner, Stylianos A Pyxaras
Coronary calcifications remain associated to increased rate of complications and worse clinical outcomes, particularly in the setting of in-stent restenosis. We present the first reported case of combined rotational atherectomy and intravascular lithotripsy for the treatment of heavily calcified neoatherosclerosis.
October 27, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/30413345/simple-percutaneous-coronary-interventions-using-the-modification-of-complex-coronary-lesion-with-excimer-laser
#10
REVIEW
Keisuke Nakabayashi, Daisuke Sunaga, Nobuhito Kaneko, Akihiro Matsui, Kazuhiko Tanaka, Hiroshi Ando, Minoru Shimizu
Excimer laser coronary atherectomy (ELCA), a unique percutaneous coronary intervention (PCI) device, comprises a monorail-type system and is compatible with any standard 0.014-inch guidewire. ELCA is the only device that vaporizes the atherosclerotic plaques or modifies underlying plaque located underneath to a hard tissue, such as severe calcification or a stent. Therefore, ELCA differs from other coronary atherectomy devices and is useful for patients with acute coronary syndrome, chronic total occlusion or under-expanded stents...
October 26, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/30413346/the-left-distal-trans-radial-artery-access-for-coronary-angiography-and-intervention-a-us-experience
#11
Karim M Al-Azizi, Vikram Grewal, Kyle Gobeil, Khawar Maqsood, Ali Haider, Amir Mohani, Gregory Giugliano, Amir S Lotfi
BACKGROUND: The radial artery is the access of choice in many catheterization labs around the world due to its proven benefits over the femoral artery access. There has been growing interest in the left radial artery. We sought to evaluate the feasibility, safety and complication rates of the left distal radial artery (ldTRA) access for cardiac catheterization. METHODS: This is a single arm retrospective study evaluating the feasibility and safety of performing cardiac catheterization through ldTRA...
October 25, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/30414798/the-pt-cr-everolimus-eluting-stent-with-bioabsorbable-polymer-in-the-treatment-of-patients-with-acute-coronary-syndromes-results-from-the-synergy-acs-registry
#12
Jose M de la Torre Hernandez, Raul Moreno, Nieves Gonzalo, Ricardo Rivera, Jose A Linares, Gabriela Veiga Fernandez, Antonio Gomez Menchero, Bruno Garcia Del Blanco, Felipe Hernandez, Tomas Benito Gonzalez, Asier Subinas, Javier Escaned
OBJECTIVES: We investigated the safety and efficacy of the bioabsorbable polymer-coated, everolimus-eluting coronary stent (SYNERGY) stent in a real-world study population with acute coronary syndromes (ACS). BACKGROUND: A number of clinical trials support the overall efficacy and safety of the SYNERGY stent. However, a recent trial (TIDES-ACS) in the context of ACS reported worrying figures of infarction and definite/probable stent thrombosis in the SYNERGY control arm...
October 18, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/30391212/fulminant-presentation-of-a-failed-tavr-valve-successful-revision-with-a-transcatheter-approach-case-report-and-review-of-the-literature
#13
REVIEW
Ashleigh Long, Paul Mahoney
Transcatheter Aortic Valve Replacement (TAVR) has evolved as a strategy for managing aortic stenosis in a growing proportion of patients considered at high or intermediate surgical risk. Though early data has demonstrated excellent durability and life span of transcatheter valves up to five years, there is an absence of case based studies in the literature regarding transcatheter valve failure after TAVR, and outcomes of subsequent redo TAVR Valve-in-Valve (VIV) procedures. We report here a successful case of emergent, catheter-based treatment for severe, highly symptomatic valve in valve restenosis of a 5 year old Sapien valve...
October 18, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/30361120/perforation-of-a-saphenous-vein-graft-anastomosed-at-a-y-configuration-to-the-left-internal-mammary-artery
#14
REVIEW
Andreas S Triantafyllis, Joost D E Haeck, Eveline G J A van Dijk, Guus R G Brueren, Eleftherios Spartalis, Pim A L Tonino
Perforation of a saphenous vein graft (SVG) is a rare, yet dreadful complication during percutaneous coronary intervention (PCI). Perforation of a SVG arising at a Y-construction from the left internal mammary artery (LIMA) can be catastrophic since manipulations and material delivery through the single LIMA inflow can aggravate ischemia and accelerate hemodynamic collapse. Prior CABG and pericardial obliteration should not offer reassurance against tamponade, since coronary perforation in these patients may cause the development of loculated pericardial effusions, a complication associated with high mortality...
October 16, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/30415969/resting-coronary-flow-varies-with-normal-cardiac-catheter-laboratory-stimuli
#15
Bhavik N Modi, Haseeb Rahman, Satpal Arri, Howard Ellis, Mark T Mills, Rupert Williams, Kaleab Asrress, Brian Clapp, Simon Redwood, Divaka Perera
BACKGROUND: Growing evidence supports physiology-guided revascularization, with Fractional Flow Reserve (FFR) the most commonly used invasive measure of coronary blood flow impairment at the time of diagnostic angiography. Recently, there has been growing interest in stenosis severity indices measured at rest, such as Instantaneous Wave Free Ratio (iFR) and the ratio of distal coronary to aortic pressure at rest (resting Pd/Pa). Their reliability may, theoretically, be more susceptible to changes in microvascular tone and coronary flow...
October 15, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/30344055/impact-of-prior-revascularization-on-the-outcomes-of-patients-presenting-with-st-elevation-myocardial-infarction-and-cardiogenic-shock
#16
Prabhjot Singh, Fabio V Lima, Puja Parikh, Chencan Zhu, William Lawson, Anil Mani, Allen Jeremias, Jie Yang, Luis Gruberg
BACKGROUND: Patient presenting with ST-elevation myocardial infarction (STEMI) complicated by cardiogenic shock (CS) have extremely high mortality rates. OBJECTIVES: We sought to assess the impact of prior revascularization by either coronary artery bypass graft surgery (CABG) or percutaneous coronary intervention (PCI) on the in-hospital and 12-month outcomes and compare them with revascularization-naïve patients. METHODS AND RESULTS: Between 1/2010 and 5/2017, a total of 241 consecutive patients were admitted to our institution with STEMI and CS as defined by New York State Percutaneous Coronary Interventions Reporting System (PCIRS) and underwent primary PCI...
October 15, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/30340954/primary-mr-remains-undertreated
#17
Ted Feldman, Robert Smith, Jeffrey J Popma
No abstract text is available yet for this article.
October 15, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/30401590/association-of-race-with-long-term-outcomes-in-patients-undergoing-popliteal-and-infra-popliteal-percutaneous-peripheral-arterial-interventions
#18
Mohammad Alasaad, Anwar Zaitoun, Suzan Szpunar, Thomas Lalonde, Howard S Rosman, Rajendra H Mehta, Hiroshi Yamasaki, Hussein Othman
BACKGROUND: Race-related differences in clinical features, presentation, treatment and outcomes of patients with various cardiovascular diseases have been reported in previous studies. However, the long-term outcomes in black versus white patients with popliteal and/or infra-popliteal peripheral arterial disease (PAD) undergoing percutaneous peripheral vascular interventions (PVI) are not well known. METHODS AND RESULTS: We retrospectively evaluated long-term outcomes in 696 patients (263 blacks and 433 whites) who underwent PVI for popliteal and/or infra-popliteal PAD at our institution between 2007 and 2012...
October 11, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/30340953/changing-the-paradigm-in-renal-denervation-is-trans-urethral-access-the-key-to-effective-blood-pressure-reduction
#19
LETTER
Nachiket J Patel, Ajay U Mhatre, Richard R Heuser
No abstract text is available yet for this article.
October 11, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/30344056/summary-of-the-2018-medicare-evidence-development-coverage-advisory-committee-medcac-for-transcatheter-aortic-valve-replacement
#20
REVIEW
Toby Rogers, Jaffar M Khan, J James Edelman, Ron Waksman
Medicare coverage for transcatheter aortic valve replacement (TAVR) in the United States (US) is governed by the 2012 National Coverage Determination (NCD 20.32), which enshrined minimum numbers of TAVR, surgical aortic valve replacement, and percutaneous coronary intervention that centers must perform to begin or maintain TAVR programs. In July 2018, the Centers for Medicare and Medicaid Services (CMS) convened a meeting of the Medicare Evidence Development & Coverage Advisory Committee (MEDCAC) to review the evidence for setting minimum procedure volume requirements and to evaluate the impact of such requirements on access to care...
October 9, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
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