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Journal of Geriatric Cardiology: JGC

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https://www.readbyqxmd.com/read/28408919/transcatheter-aortic-valve-implantation-a-revolution-in-the-therapy-of-elderly-and-high-risk-patients-with-severe-aortic-stenosis
#1
REVIEW
Teoman Kilic, Irem Yilmaz
Transcatheter aortic valve implantation (TAVI) represents a real revolution in the field of interventional cardiology for the treatment of elderly or high-risk surgical patients with severe symptomatic aortic valve stenosis. Today, TAVI seems to play a key and a reliable role in the treatment of intermediate and maybe low-risk patients with severe aortic stenosis. TAVI has also evolved from a complex and hazardous procedure into an effective and safe therapy by the development of new generation devices. This article aims to review the background and future of TAVI, clinical trials and registries with old and new generation TAVI devices and to focus on some open issues related to post-procedural outcomes...
March 2017: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/28491090/recurrent-acute-myocardial-infarction-and-atrial-fibrillation
#2
Levent Cerit
No abstract text is available yet for this article.
February 2017: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/28491089/successful-treatment-of-intracardiac-air-embolism-using-intracardiac-catheter-aspiration
#3
Ae-Young Her, Yong Hoon Kim, Da Hye Moon, Ji Hyun Kim, Jae Hoon Jeong, Sung-Hyun Park, Jin Seon Jeong
No abstract text is available yet for this article.
February 2017: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/28491088/novel-biomarkers-for-cardiovascular-risk-prediction
#4
REVIEW
Juan Wang, Guo-Juan Tan, Li-Na Han, Yong-Yi Bai, Miao He, Hong-Bin Liu
Cardiovascular disease (CVD) is the leading cause of death and disability worldwide. The primary prevention of CVD is dependent upon the ability to identify high-risk individuals long before the development of overt events. This highlights the need for accurate risk stratification. An increasing number of novel biomarkers have been identified to predict cardiovascular events. Biomarkers play a critical role in the definition, prognostication, and decision-making regarding the management of cardiovascular events...
February 2017: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/28491087/neutrophil-to-lymphocyte-ratio-compared-to-n-terminal-pro-brain-natriuretic-peptide-as-a-prognostic-marker-of-adverse-events-in-elderly-patients-with-chronic-heart-failure
#5
Wei Yan, Rui-Jun Li, Qian Jia, Yang Mu, Chun-Lei Liu, Kun-Lun He
BACKGROUND: The neutrophil-to-lymphocyte (N/L) ratio has been associated with poor prognosis in patients with heart failure, but it has not been compared with N-terminal pro-brain natriuretic peptide (NT-proBNP) in elderly patients with chronic heart failure (CHF). We sought to make this comparison. METHODS: A total of 1355 elderly patients with CHF were analyzed. A multivariate logistic regression model was used to analyze the variables associated with atrial fibrillation (AF)...
February 2017: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/28491086/left-univentricular-pacing-for-cardiac-resynchronization-therapy-using-rate-adaptive-atrioventricular-delay
#6
Li-Jin Pu, Yu Wang, Lu-Lu Zhao, Tao Guo, Shu-Min Li, Bao-Tong Hua, Ping Yang, Jun Yang, Yan-Zhou Lu, Liu-Qing Yang, Ling Zhao, Hai-Yun Luo
OBJECTIVE: To evaluate left univentricular (LUV) pacing for cardiac resynchronization therapy (CRT) using a rate-adaptive atrioventricular delay (RAAVD) algorithm to track physiological atrioventricular delay (AVD). METHODS: A total of 72 patients with congestive heart failure (CHF) were randomized to RAAVD LUV pacing versus standard biventricular (BiV) pacing in a 1: 1 ratio. Echocardiography was used to optimize AVD for both groups. The effects of sequential BiV pacing and LUV pacing with optimized A-V (right atrio-LV) delay using an RAAVD algorithm were compared...
February 2017: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/28491085/stenting-versus-non-stenting-treatment-of-intermediate-stenosis-culprit-lesion-in-acute-st-segment-elevation-myocardial-infarction-a-multicenter-randomized-clinical-trial
#7
Jing Dai, Shu-Zheng Lyu, Yun-Dai Chen, Xian-Tao Song, Min Zhang, Wei-Min Li, Yang Zheng, Shang-Yu Wen, Shao-Ping Nie, Yu-Jie Zeng, Hai Gao, Yi-Tong Ma, Shu-Yang Zhang, Li-Jun Guo, Zheng Zhang
BACKGROUND: The benefit/risk ratio of stenting in acute ST-segment elevation myocardial infarction (STEMI) patients with single vessel intermediate stenosis culprit lesions merits further study, therefore the subject of the present study. METHODS AND RESULTS: It was a prospective, multicenter, randomized controlled trial. Between April 2012 and July 2015, 399 acute STEMI patients with single vessel disease and intermediate (40%-70%) stenosis of the culprit lesion before or after aspiration thrombectomy and/or intracoronary tirofiban (15 µg/kg) were enrolled and were randomly assigned (1: 1) to stenting group (n = 201) and non-stenting group (n = 198)...
February 2017: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/28491084/the-impact-of-optimal-medical-therapy-at-discharge-on-mortality-in-patients-with-coronary-artery-disease
#8
Shi-Jian Chen, Wei Liu, Bao-Tao Huang, Jia-Yu Tsauo, Xiao-Bo Pu, Yong Peng, Mao Chen, De-Jia Huang
OBJECTIVE: To analyze the current usage of optimal medical therapy (OMT), influencing factors, and the predictive value of OMT for all-cause mortality in coronary artery disease (CAD) patients with different subgroups. METHODS: A total of 3176 CAD patients confirmed by coronary angiography were included. OMT was defined as the combination of anti-platelet drugs, statins, beta blockers, and angiotensin converting enzyme inhibitors or angiotensin receptor blockers...
February 2017: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/28491083/comparison-of-the-performance-of-the-crusade-acuity-horizons-and-action-bleeding-scores-in-acs-patients-undergoing-pci-insights-from-a-cohort-of-4939-patients-in-china
#9
Ran Liu, Shu-Zheng Lyu, Guan-Qi Zhao, Wen Zheng, Xiao Wang, Xue-Dong Zhao, Sheng-Hui Zhou, Lei Zhen, Shao-Ping Nie
BACKGROUND: The CRUSADE, ACTION and ACUITY-HORIZONS scores are commonly used for predicting in-hospital major bleeding events in patients with acute coronary syndrome (ACS), but the homogeneous nature of these models' population limits simple extrapolation to other local population. We aimed to compare the performance of the three risk models in Chinese patients. METHODS: We evaluated the performance of the three predicting scores for predicting in-hospital major bleeding events defined by thrombolysis in myocardial infarction (TIMI) serious (major and minor) episodes, in a cohort of Chinese ACS patients with either non-ST-elevation ACS (NSTE-ACS) or ST-elevation myocardial infarction (STEMI)...
February 2017: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/28491082/altered-serum-level-of-cartilage-oligomeric-matrix-protein-and-its-association-with-coronary-calcification-in-patients-with-coronary-heart-disease
#10
Fang-Fang Wang, Lahati Ha, Hai-Yi Yu, Lin Mi, Jiang-Li Han, Wei Gao
BACKGROUND: Cartilage oligomeric matrix protein (COMP) is mainly found in the skeletal system and vascular smooth muscle cells. Recent researches showed that it had a protective function on blood vessels and could also inhibit vascular calcification. We investigated the serum COMPs in coronary heart disease (CHD) patients, and the relationship between serum COMP and the calcification of coronary artery. METHODS: A total of 233 consecutive chest pain patients who first underwent coronary angiography followed by multi-slice computed tomography (MSCT) within six months were recruited and divided into two groups according to the coronary angiography luminal diameter narrowing percentages: CHD group (diameter narrowing ≥ 50%, n = 194) and control group (diameter narrowing < 50%, n = 39)...
February 2017: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/28491081/safety-and-efficacy-of-transradial-coronary-angiography-and-intervention-in-patients-older-than-80-years-from-the-korean-transradial-intervention-prospective-registry
#11
Hoyoun Won, Wang Soo Lee, Sang-Wook Kim, Byung Ryul Cho, Young Jin Youn, Young-Hyo Lim, Min-Ho Lee, Jae-Hwan Lee, Seung-Woon Rha
BACKGROUND: Radial artery access for coronary procedures is a safe and beneficial technique. However, elderly patients have been considered as a higher risk group of access site related complications compared to younger patients. This study was conducted to investigate the feasibility and safety of transradial coronary angiography or intervention in the elderly. METHODS: A total of 6132 patients from Korean Transradial Intervention Prospective Registry at 20 centers were analyzed...
February 2017: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/28270846/left-ventricular-pseudoaneurysm
#12
Hee Hwa Ho, Dasdo Antonius Sinaga, Evelyn Lee, Timothy James Watson, Jimmy Kim Fatt Hon
No abstract text is available yet for this article.
January 2017: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/28270845/ecg-stress-test-induced-atrial-ischemia-in-a-patient-with-old-inferior-myocardial-infarction-due-to-a-distal-coronary-artery-lesion
#13
András Vereckei, Gábor Katona, Zsuzsanna Szelényi, Edit Takács, Pál Maurovich-Horvat, Dávid Becker
No abstract text is available yet for this article.
January 2017: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/28270844/new-generations-of-dihydropyridines-for-treatment-of-hypertension
#14
REVIEW
Angela L Wang, Costantino Iadecola, Gang Wang
Since the calcium channel blocker (CCB) has become one of the most prescribed agents for antihypertensive monotherapy in the world, this brief review will focus on the recent research and development of the dihydropyridine (DHP) CCB, addressing pharmacological mechanisms for the clinical efficacy of the third and fourth generations of the DHP CCBs, especially on their possible central mechanisms underlying lowering blood pressure.
January 2017: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/28270843/liraglutide-directly-protects-cardiomyocytes-against-reperfusion-injury-possibly-via-modulation-of-intracellular-calcium-homeostasis
#15
Shun-Ying Hu, Ying Zhang, Ping-Jun Zhu, Hao Zhou, Yun-Dai Chen
BACKGROUND: Liraglutide is glucagon-like peptide-1 receptor agonist for treating patients with type 2 diabetes mellitus. Our previous studies have demonstrated that liraglutide protects cardiac function through improving endothelial function in patients with acute myocardial infarction undergoing percutaneous coronary intervention. The present study will investigate whether liraglutide can perform direct protective effects on cardiomyocytes against reperfusion injury. METHODS: In vitro experiments were performed using H9C2 cells and neonatal rat ventricular cadiomyocytes undergoing simulative hypoxia/reoxygenation (H/R) induction...
January 2017: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/28270842/admission-white-blood-cell-count-predicts-short-term-clinical-outcomes-in-patients-with-uncomplicated-stanford-type-b-acute-aortic-dissection
#16
Zhao-Ran Chen, Bi Huang, Hai-Song Lu, Zhen-Hua Zhao, Ru-Tai Hui, Yan-Min Yang, Xiao-Han Fan
OBJECTIVES: Inflammation has been shown to be related with acute aortic dissection (AAD). The present study aimed to evaluate the association of white blood cell counts (WBCc) on admission with both in-hospital and long-term all-cause mortality in patients with uncomplicated Stanford type B AAD. METHODS: From 2008 to 2010, a total of 377 consecutive patients with uncomplicated type B AAD were enrolled and then followed up. Clinical data and WBCc on admission were collected...
January 2017: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/28270841/conditions-for-autonomous-choice-a-qualitative-study-of-older-adults-experience-of-decision-making-in-tavr
#17
Elisabeth Skaar, Anette Hylen Ranhoff, Jan Erik Nordrehaug, Daniel E Forman, Margrethe Aase Schaufel
BACKGROUND: Patient autonomy is a leading principle in bioethics and a basis for shared decision making. This study explores conditions for an autonomous choice experienced by older adults who recently underwent trans-catheter aortic valve replacement (TAVR). METHODS: Qualitative study entailing semi-structured interviews of a purposive sample of ten older (range 73-89, median 83.5 years) adults after TAVR (median 23 days). The study setting was a cardiac department at a university hospital performing TAVR since 2010...
January 2017: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/28270840/nine-year-clinical-outcomes-of-drug-eluting-stents-vs-bare-metal-stents-for-large-coronary-vessel-lesions
#18
Dong Yin, Jia Li, Yue-Jin Yang, Yang Wang, Yan-Yan Zhao, Shi-Jie You, Shu-Bin Qiao, Bo Xu, Ke-Fei Dou
OBJECTIVES: To evaluate the very long-term safety and effectiveness of drug-eluting stents (DES) compared to bare-metal stents (BMS) for patients with large coronary vessels. METHODS: From April 2004 to October 2006, 2407 consecutive patients undergoing de novo lesion percutaneous coronary intervention with reference vessel diameter greater than or equal to 3.5 mm at Fu Wai Hospital in Beijing, China, were prospectively enrolled into this study. We obtained 9-year clinical outcomes including death, myocardial infarction (MI), thrombosis, target lesion revascularization (TLR), target vessel revascularization (TVR), and major adverse cardiac events (MACE, the composite of death, MI, and TVR)...
January 2017: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/28270839/which-prognostic-factors-should-be-used-in-pulmonary-arterial-hypertension-in-elderly-patients
#19
Bahri Akdeniz, Ebru Ozpelit
In recent times, the prevalence of pulmonary arterial hypertension (PAH) is more commonly seen among elderly populations. The increased prevalence of hypertension, diabetes, obesity, arterial stiffness, as well as diastolic dysfunction, may cause endothelial dysfunction and affect pulmonary vasculature. Furthermore, older patients have certain differences in clinical characteristics and outcomes. In this article, the special characteristics of aging in PAH patients have been reviewed, while the risk predictors of elderly patients are also discussed...
January 2017: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/28270838/clinical-and-hemodynamic-profiles-of-elderly-patients-with-pulmonary-arterial-hypertension-a-single-center-prospective-study
#20
Ebru Ozpelit, Bahri Akdeniz, Dilek Sezgin, Can Sevinc, Kemal Can Tertemiz, Mehmet Emre Ozpelit, Mustafa Baris, Nezihi Baris
BACKGROUNDS: Pulmonary arterial hypertension (PAH) was previously considered an illness that affects mostly the young, but now it is also increasingly recognized in the elderly. The aim of this study was to compare the features of elderly versus younger patients diagnosed with PAH, and to define the prognostic factors which affect their long-term survival. METHODS: In this prospective, single center study, the clinical, echocardiographic, hemodynamic characteristics, and the outcomes of younger (18-65 years) and elderly (≥ 65 years) patients with definitive diagnosis of precapillary PAH were compared...
January 2017: Journal of Geriatric Cardiology: JGC
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