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Blood Transfusion, Trasfusione del Sangue

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https://www.readbyqxmd.com/read/29120704/xvi-convegno-triennale-sui-problemi-clinici-e-sociali-dell-emofilia-e-delle-malattie-emorragiche-congenite-napoli-9-12-novembre-2017
#1
Giovanni Di Minno, Elena Santagostino, Massimo Morfini, Hamisa J Hassan, Angelo C Molinari, Rita C Santoro, Annarita Tagliaferri, Antonio Coppola
No abstract text is available yet for this article.
November 7, 2017: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/29106354/characteristics-of-thawed-pooled-cryoprecipitate-stored-at-refrigerated-temperature-for-24-hours
#2
Esther P Soundar, Meredith Reyes, Laura Korte, Arthur Bracey
BACKGROUND: The need for thawed cryoprecipitate is growing. However, according to current guidelines, the shelf-life of pooled thawed cryoprecipitate at room temperature is limited because of possible bacterial contamination and loss of clotting factor activity. Here we assessed microbial growth and retention of clotting activity in cryoprecipitate stored at 4 °C after thawing to see whether its shelf life could be safely extended. MATERIALS AND METHODS: Pooled thawed cryoprecipitate units (n=10) were maintained at room temperature for 6 hours and then placed at 1-6 °C for 18 hours after thawing...
October 30, 2017: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/29106353/testing-direct-oral-anticoagulants-embedding-in-structured-long-term-care
#3
EDITORIAL
Hugo Ten Cate
No abstract text is available yet for this article.
October 26, 2017: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/29106355/reply-to-high-titre-inhibitors-in-previously-untreated-patients-with-severe-haemophilia-a-receiving-recombinant-or-plasma-derived-factor-viii-a-budget-impact-analysis-by-messori-et-al
#4
LETTER
Albert Farrugia, Megha Bansal
No abstract text is available yet for this article.
October 3, 2017: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/29106356/cell-salvage-for-postpartum-haemorrhage-during-vaginal-delivery-a-case-series
#5
Grace Lim, Eleni Kotsis, Jamie M Zorn, Patricia L Dalby, Catherine J Ralph, Jonathan H Waters
BACKGROUND: The safety and effectiveness of cell salvage for vaginal delivery is unknown. This case series aimed to assess the utility and adverse events related to the use of cell salvage for maternal haemorrhage during vaginal delivery. MATERIALS AND METHODS: A cohort study design was chosen, focused on postpartum haemorrhages that occurred after vaginal delivery for which cell salvage equipment was requested to be set up in the labour and delivery room outside of a sterile operating room environment...
September 29, 2017: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/29106357/position-paper-on-laboratory-testing-for-patients-on-direct-oral-anticoagulants-a-consensus-document-from-the-siset-fcsa-sibioc-and-sipmel
#6
Armando Tripodi, Walter Ageno, Marcello Ciaccio, Cristina Legnani, Giuseppe Lippi, Cesare Manotti, Rossella Marcucci, Marco Moia, Benedetto Morelli, Daniela Poli, Agostino Steffan, Sophie Testa
Although direct oral anticoagulants (DOAC) do not require dose-adjustment on the basis of laboratory test results, the measurement of their anticoagulant effect is useful in special situations. This position paper issued by the Italian Scientific Societies that are mainly involved in the management of patients on DOAC is aimed at providing guidance to care-givers on which tests should be used and the situations in which testing is useful. The guidance is based on the data from the literature so far available and/or on consensus among experts...
September 13, 2017: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/29059042/k-antigen-blocking-in-a-case-of-haemolytic-disease-of-the-foetus-and-newborn
#7
LETTER
Silvia Manfroi, Claudio Velati
No abstract text is available yet for this article.
October 2017: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/29059041/seroprevalence-of-hepatitis-e-virus-among-blood-donors-in-northern-italy-sondrio-lombardy-determined-by-three-different-assays
#8
Cristina Galli, Laura Fomiatti, Catia Tagliacarne, Claudio Velati, Alessandro R Zanetti, Silvana Castaldi, Luisa Romanò
No abstract text is available yet for this article.
October 2017: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/29053100/ten-years-since-the-last-chikungunya-virus-outbreak-in-italy-history-repeats-itself
#9
EDITORIAL
Giuseppe Marano, Simonetta Pupella, Ilaria Pati, Francesca Masiello, Massimo Franchini, Stefania Vaglio, Claudio Velati, Giancarlo M Liumbruno
No abstract text is available yet for this article.
October 2017: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/28686154/influence-of-red-blood-cell-derived-microparticles-upon-vasoregulation
#10
REVIEW
Ahmed S Said, Allan Doctor
Here we review recent data and the evolving understanding of the role of red blood cell-derived microparticles (RMPs) in normal physiology and in disease progression. Microparticles (MPs) are small membrane vesicles derived from various parent cell types. MPs are produced in response to a variety of stimuli through several cytoskeletal and membrane phospholipid changes. MPs have been investigated as potential biomarkers for multiple disease processes and are thought to have biological effects, most notably in: promotion of coagulation, production and handling of reactive oxygen species, immune modulation, angiogenesis, and in apoptosis...
October 2017: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/28488967/purinergic-control-of-red-blood-cell-metabolism-novel-strategies-to-improve-red-cell-storage-quality
#11
REVIEW
Kaiqi Sun, Angelo D'alessandro, Yang Xia
Transfusion of stored blood is regarded as one of the great advances in modern medicine. However, during storage in the blood bank, red blood cells (RBCs) undergo a series of biochemical and biomechanical changes that affect cell morphology and physiology and potentially impair transfusion safety and efficacy. Despite reassuring evidence from clinical trials, it is universally accepted that the storage lesion(s) results in the altered physiology of long-stored RBCs and helps explain the rapid clearance of up to one-fourth of long-stored RBCs from the recipient's bloodstream at 24 hours after administration...
October 2017: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/28488960/towards-pathogen-inactivation-of-red-blood-cells-and-whole-blood-targeting-viral-dna-rna-design-technologies-and-future-prospects-for-developing-countries
#12
REVIEW
Victor J Drew, Lassina Barro, Jerard Seghatchian, Thierry Burnouf
Over 110 million units of blood are collected yearly. The need for blood products is greater in developing countries, but so is the risk of contracting a transfusion-transmitted infection. Without efficient donor screening/viral testing and validated pathogen inactivation technology, the risk of transfusion-transmitted infections correlates with the infection rate of the donor population. The World Health Organization has published guidelines on good manufacturing practices in an effort to ensure a strong global standard of transfusion and blood product safety...
October 2017: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/28287385/interference-of-direct-oral-anticoagulants-in-haemostasis-assays-high-potential-for-diagnostic-false-positives-and-false-negatives
#13
EDITORIAL
Emmanuel J Favaloro, Giuseppe Lippi
No abstract text is available yet for this article.
October 2017: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/28287382/effect-of-dabigatran-on-a-prothrombinase-based-assay-for-detecting-activated-protein-c-resistance-an-ex-vivo-and-in-vitro-study-in-normal-subjects-and-factor-v-leiden-carriers
#14
Gianluca Gessoni, Sara Valverde, Letizia Valle, Pierpaolo Caruso, Francesca Gessoni, Roberto Valle
BACKGROUND: The aim of this study was to evaluate ex vivo and in vitro interference of a direct factor IIa inhibitor, dabigatran, on a prothrombinase-based assay to detect activated protein C resistance. MATERIALS AND METHODS: An ex vivo study was performed in six heterozygous factor V Leiden carriers and 12 normal subjects without the factor V Leiden mutation who were treated with dabigatran. An in vitro study was also performed considering 12 plasma samples (six from normal subjects and six from heterozygous factor V Leiden carriers) spiked with dabigatran...
October 2017: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/27893359/collection-of-umbilical-cord-blood-for-banking-collection-rate-and-factors-influencing-collection
#15
LETTER
Veronica Valle, Maria Screnci, Emilia Murgi, Martina Capozzi, Gabriella Girelli
No abstract text is available yet for this article.
October 2017: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/27893354/summary-report-of-the-first-international-conference-on-inhibitors-in-haemophilia-a
#16
Sebastien Lacroix-Desmazes, David W Scott, Jenny Goudemand, Marijke Van Den Berg, Michael Makris, Alice S Van Velzen, Elena Santagostino, David Lillicrap, Frits R Rosendaal, Anneliese Hilger, Zuben E Sauna, Johannes Oldenburg, Lorenzo Mantovani, M Elisa Mancuso, Craig Kessler, Charles R M Hay, Paul Knoebl, Giovanni Di Minno, Keith Hoots, Amanda Bok, Mark Brooker, Erica Buoso, Pier Mannuccio Mannucci, Flora Peyvandi
No abstract text is available yet for this article.
October 2017: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/27723450/fully-automated-clinical-grade-bone-marrow-processing-a-single-centre-experience
#17
Benedetta Mazzanti, Serena Urbani, Simone Dal Pozzo, Paola Bufano, Lara Ballerini, Alessia Gelli, Irene Sodi, Irene Donnini, Massimo Di Gioia, Stefano Guidi, Julien Camisani, Riccardo Saccardi
BACKGROUND: Clinical grade processing of harvested bone marrow is required in various clinical situations, particularly in the management of ABO mismatching in allogeneic haematopoietic stem cell transplantation (HSCT) and in regenerative medicine. MATERIAL AND METHODS: We report a single-centre experience using a fully automated, clinical grade, closed system (Sepax, Biosafe, Switzerland). From 2003 to 2015, 125 procedures were performed in our laboratory, including buffy-coat production for HSCT (n=58), regenerative medicine in an orthopaedic setting (n=54) and density-gradient separation in a trial for treatment of critical limb ischaemia (n=13)...
October 2017: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/27723449/selection-strategies-for-newly-registered-blood-donors-in-european-countries
#18
Ryanne W Lieshout-Krikke, Dragoslav Domanovic, Wim De Kort, Wolfgang Mayr, Giancarlo M Liumbruno, Simonetta Pupella, Johann Kurz, Folke Knutson, Sheila Maclennan, Gilles Folléa
BACKGROUND: Two selection strategies for newly-registered blood donors are available: a single-visit selection called the standard selection procedure (SSP), and a two-stage selection named predonation and donation screening (PDS). This study reviews the selection strategies for newly-registered donors currently applied in European countries. MATERIAL AND METHODS: We collected data on donor selection procedures, blood donation, laboratory screening and HIV, HCV and HBV positive donors/donations from 2010 to 2013 in 30 European countries by using questionnaires...
October 2017: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/27483487/functional-characterisation-of-the-type-1-von-willebrand-disease-candidate-vwf-gene-variants-p-m771i-p-l881r-and-p-p1413l
#19
Ergul Berber, Mehmet Ozbil, Christine Brown, Zafer Baslar, S Hande Caglayan, David Lillicrap
BACKGROUND: Abnormalities in the biosynthetic pathway or increased clearance of plasma von Willebrand factor (VWF) are likely to contribute to decreased plasma VWF levels in inherited type 1 von Willebrand disease (VWD). Recent studies demonstrated that 65% of type 1 VWD patients have candidate VWF mutations, the majority of which are missense variants. The purpose of this study was to explore the effects of three VWF missense mutations (p.M771I, p.L881R and p.P1413L) located in different functional domains of VWF, reported as candidate mutations in type 1 VWD patients in the course of the MCMDM-1VWD study...
October 2017: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/27483483/intravenous-iron-supplementation-with-intra-articular-administration-of-tranexamic-acid-reduces-the-rate-of-allogeneic-transfusions-after-simultaneous-bilateral-total-knee-arthroplasty
#20
Dong Won Suh, Seung-Beom Han, Jong-Hoon Park, Kuhoang Cheong, Bong Soo Kyung
BACKGROUND: Peri-operative intravenous administration of iron supplementation seems a good option to reduce allogeneic blood transfusion in major orthopaedic surgery. However, its efficacy in simultaneous bilateral total knee arthroplasty has not been studied. MATERIALS AND METHODS: From December 2014 to May 2015, a total of 72 consecutive patients underwent simultaneous bilateral total knee arthroplasty and received peri-operative intravenous iron supplementation (iron isomaltoside 1000: 600 mg pre-operatively and 400 mg 1 week post-operatively) and intra-articular tranexamic acid (2 g in 20 mL saline at the end of surgery), and were managed with a restrictive transfusion trigger (haemoglobin <7 g/dL)...
October 2017: Blood Transfusion, Trasfusione del Sangue
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