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Blood Transfusion, Trasfusione del Sangue

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https://www.readbyqxmd.com/read/29757137/reversal-of-apixaban-induced-alterations-in-haemostasis-by-different-coagulation-factor-concentrates-in-patients-after-hip-or-knee-replacement-surgery
#1
Katrin Schmidt, Kerstin Krüger, Elisabeth Langer, Martin Schmutzler, Elke Johnen, Klaus D Wernecke, Christian Von Heymann, Mareike K Körber
BACKGROUND: Apixaban is a direct oral anticoagulant (DOAC) with a specific inhibition of activated factor X (FXa). In case of bleeding or need of urgent surgery a direct antidote is not yet available. Off-label application of non-specific haemostatic agents, such as prothrombin complex concentrate (PCC) and recombinant FVIIa (rFVIIa), has been reported to reverse the effects of apixaban in in vitro and animal studies. The aim of this study is to measure the reversal potential of PCC and rFVIIa in patients with prophylactic apixaban concentrations...
May 11, 2018: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/29757133/haemolysis-index-for-the-screening-of-intravascular-haemolysis-a-novel-diagnostic-opportunity
#2
REVIEW
Giuseppe Lippi, Emmanuel J Favaloro, Massimo Franchini
The diagnostic approach to patients with intravascular haemolysis remains challenging, since no first-line laboratory test seems to be entirely suitable for the screening of this condition. Recent evidence shows that an enhanced cell-free haemoglobin (fHb) concentration in serum or plasma is a reliable marker of red blood cell injury, and may also predict clinical outcomes in patients with different forms of haemolytic anaemias. However, the routine use of the haemiglobincyanide assay, the current reference method for measuring fHb, seems unsuitable for a timely diagnosis of intravascular haemolysis, for many safety and practical reasons...
May 8, 2018: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/29757135/a-nationwide-retrospective-study-on-prevalence-of-hepatitis-e-virus-infection-in-italian-blood-donors
#3
Enea Spada, Simonetta Pupella, Giulio Pisani, Roberto Bruni, Paola Chionne, Elisabetta Madonna, Umbertina Villano, Matteo Simeoni, Sara Fabi, Giuseppe Marano, Cinzia Marcantonio, Patrizio Pezzotti, Anna R Ciccaglione, Giancarlo M Liumbruno
BACKGROUND: In Europe, hepatitis E virus (HEV) infection is mainly a food-borne zoonosis, but it can also be transmitted by blood transfusion. It is usually a mild and self-limited infection. However, immunocompromised persons, who are also those more likely to undergo blood transfusions, may develop chronic hepatitis and often cirrhosis. Since this is a potential threat to blood safety, we aimed to investigate HEV prevalence in Italian blood donors. MATERIALS AND METHODS: We used plasma donations collected during 2015-2016 by blood services (BS) scattered throughout the Italian regions and intended for the production of plasma-derived medicines...
May 4, 2018: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/29757139/a-proposal-for-a-rational-transfusion-strategy-in-patients-of-european-and-north-african-descent-with-weak-d-type-4-0-and-4-1-phenotypes
#4
EDITORIAL
Willy A Flegel, Thierry Peyrard, Jacques Chiaroni, Christophe Tournamille, Déborah Jamet, France Pirenne
No abstract text is available yet for this article.
May 3, 2018: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/29757130/tranexamic-acid-to-prevent-post-partum-haemorrhage
#5
EDITORIAL
Riana Van Der Linde, Emmanuel J Favaloro
No abstract text is available yet for this article.
May 3, 2018: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/29757134/second-line-therapy-in-paediatric-warm-autoimmune-haemolytic-anaemia-guidelines-from-the-associazione-italiana-onco-ematologia-pediatrica-aieop
#6
Saverio Ladogana, Matteo Maruzzi, Piera Samperi, Annalisa Condorelli, Maddalena Casale, Paola Giordano, Lucia D Notarangelo, Piero Farruggia, Fiorina Giona, Agostino Nocerino, Silvia Fasoli, Maria L Casciana, Maurizio Miano, Fabio Tucci, Tommaso Casini, Paola Saracco, Wilma Barcellini, Alberto Zanella, Silverio Perrotta, Giovanna Russo
No abstract text is available yet for this article.
April 13, 2018: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/29757138/prenatal-non-invasive-foetal-rhd-genotyping-diagnostic-accuracy-of-a-test-as-a-guide-for-appropriate-administration-of-antenatal-anti-d-immunoprophylaxis
#7
Silvia Manfroi, Chiara Calisesi, Pietro Fagiani, Annalisa Gabriele, Gianluca Lodi, Simonetta Nucci, Susanna Pelliconi, Laura Righini, Vanda Randi
BACKGROUND: Foetal RHD genotyping can be predicted by real-time polymerase chain reaction (qPCR) using cell-free foetal DNA extracted from maternal plasma. The object of this study was to determine the diagnostic accuracy and feasibility of non-invasive RHD foetal genotyping, using a commercial multiple-exon assay, as a guide to appropriate administration of targeted antenatal immunoprophylaxis. MATERIAL AND METHODS: Cell-free foetal DNA was extracted from plasma of RhD-negative women between 11-30 weeks of pregnancy...
April 9, 2018: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/29757136/on-the-cost-utility-of-methylene-blue-photoinactivated-plasma-versus-quarantine-plasma-in-spain
#8
LETTER
Arturo Pereira, Julio Del Río-Garma, José A García-Erce
No abstract text is available yet for this article.
April 4, 2018: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/29757131/red-blood-cell-salvage-analysis-from-clotted-blood
#9
Ethan K Craig, Mark H Yazer, Jonathan H Waters
BACKGROUND: Blood clots discovered within body cavities intra-operatively are often manually broken up and placed in an autotransfusion device to recover autologous blood cells. This study evaluated the efficiency at which these red blood cells can be recovered from clot and to determine if these cells would be free of fibrin and clumping which might pose a risk of micro-emboli. MATERIALS AND METHODS: Whole blood was aliquoted into 25 mL volume samples. The blood was then allowed to clot, and after 24 hours the clotted blood was manually kneaded by hand for 1, 2, 3, or 5 minutes...
April 4, 2018: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/29757132/safety-and-efficacy-of-tranexamic-acid-for-prevention-of-obstetric-haemorrhage-an-updated-systematic-review-and-meta-analysis
#10
REVIEW
Massimo Franchini, Carlo Mengoli, Mario Cruciani, Valentino Bergamini, Francesca Presti, Giuseppe Marano, Simonetta Pupella, Stefania Vaglio, Francesca Masiello, Eva Veropalumbo, Vanessa Piccinini, Ilaria Pati, Giancarlo M Liumbruno
BACKGROUND: A number of clinical systematic review and meta-analysis have been published on the use of tranexamic in the obstetric setting. The aim of this meta-analysis was to evaluate the safety and effectiveness of tranexamic acid in reducing blood loss when given prior to caesarean delivery. MATERIALS AND METHODS: We searched the Cochrane Wounds Specialized Register, Cochrane Central, MEDLINE (through PUBMED), Embase, and SCOPUS electronic databases. We also searched clinical trials registries for ongoing and unpublished studies, and checked reference lists to identify additional studies...
April 3, 2018: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/29517972/the-post-operative-management-of-anaemia-more-efforts-are-needed
#11
EDITORIAL
Manuel Muñoz, Massimo Franchini, Giancarlo M Liumbruno
No abstract text is available yet for this article.
March 5, 2018: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/29517968/intravenous-iron-administration-for-post-operative-anaemia-management-after-colorectal-cancer-surgery-in-clinical-practice-a-single-centre-retrospective-study
#12
María Jesús Laso-Morales, Roser Vives, Susana Gómez-Ramírez, Anna Pallisera-Lloveras, Caridad Pontes
BACKGROUND: Evidence on the role of intravenous iron (IVI) supplementation after colorectal cancer (CRC) surgery is rather scant. This study was aimed at assessing the benefit of postoperative IVI administration after elective CRC surgery at our institution. MATERIALS AND METHODS: This was a single-centre, retrospective observational study including all patients who underwent CRC surgery during 2014. Anaemia was defined as a haemoglobin (Hb) <13 g/dL, regardless of gender...
March 5, 2018: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/29517963/non-replacement-therapy-for-haemophilia-treatment-fetching-the-east-by-the-west
#13
EDITORIAL
Marco Marietta, Mario Luppi
No abstract text is available yet for this article.
March 2, 2018: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/29517974/high-resolution-melting-for-f9-gene-mutation-analysis-in-patients-with-haemophilia-b
#14
Roberta Salviato, Donata Belvini, Paolo Radossi, Giuseppe Tagariello
BACKGROUND: Since 2001, we have used conformation sensitive gel electrophoresis (CSGE) as our first choice for F9 gene mutation screening, leading to the identification of about 300 mutations causing haemophilia B (HB). To circumvent the disadvantages of CSGE, we recently evaluated high-resolution melting analysis (HRM), which represents the next-generation mutation scanning technology. MATERIALS AND METHODS: In order to explore and validate HRM as a new screening method, we analysed 26 HB patients with previous CSGE-detected mutations, 22 patients with CSGE-undetectable mutations and 13 HB patients who had not been previously investigated...
February 28, 2018: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/29792592/43%C3%A2-convegno-nazionale-di-studi-di-medicina-trasfusionale-genova-23-25-maggio-2018
#15
Pierluigi Berti, Francesco Bennardello, Serelina Coluzzi, Patrizia Di Gregorio, Giuseppina Facco, Francesco Fiorin, Claudio Velati, Domenico Visceglie
No abstract text is available yet for this article.
May 23, 2018: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/29517967/the-use-of-viscoelastic-haemostatic-assays-in-non-cardiac-surgical-settings-a-systematic-review-and-meta-analysis
#16
REVIEW
Massimo Franchini, Carlo Mengoli, Mario Cruciani, Marco Marietta, Giuseppe Marano, Stefania Vaglio, Simonetta Pupella, Eva Veropalumbo, Francesca Masiello, Giancarlo M Liumbruno
BACKGROUND: Thrombelastography (TEG) and rotational thromboelastometry (ROTEM) are viscoelastic haemostatic assays (VHA) which exploit the elastic properties of clotting blood. The aim of this systematic review and meta-analysis was to evaluate the usefulness of these tests in bleeding patients outside the cardiac surgical setting. MATERIALS AND METHODS: We searched the Cochrane Library, MEDLINE, EMBASE and SCOPUS. We also searched clinical trial registries for ongoing and unpublished studies, and checked reference lists to identify additional studies...
May 2018: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/29517964/the-use-of-viscoelastic-haemostatic-assays-in-non-cardiac-surgical-settings-a-systematic-review-and-meta-analysis
#17
EDITORIAL
Raimondo De Cristofaro
No abstract text is available yet for this article.
May 2018: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/29517965/a-model-based-cost-effectiveness-analysis-of-patient-blood-management
#18
Adina Kleinerüschkamp, Patrick Meybohm, Niels Straub, Kai Zacharowski, Suma Choorapoikayil
BACKGROUND: Patient blood management (PBM) is a multidisciplinary concept focused on the management of anaemia, minimisation of iatrogenic blood loss and rational use of allogeneic blood products. The aims of this study were: (i) to analyse post-operative outcome in patients with liberal vs restrictive exposure to allogeneic blood products and (ii) to evaluate the cost-effectiveness of PBM in patients undergoing surgery. MATERIALS AND METHODS: A systematic literature review and meta-analysis were performed to compare post-operative complications in predominantly non-transfused patients (restrictive transfusion group) and patients who received one to three units of red blood cells (liberal transfusion group)...
February 16, 2018: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/29517969/abo-blood-groups-and-psychiatric-disorders-a-croatian-study
#19
Sandra Vuk Pisk, Tomislav Vuk, Ena Ivezić, Irena Jukić, Jasna Bingulac-Popović, Igor Filipčić
BACKGROUND: The prevalence of ABO alleles is different in different populations, and many studies have shown a correlation between the occurrences of some diseases and different genotypes of ABO blood groups. The aim of this study was to determine whether there is a significant association between psychiatric syndromes and ABO blood groups. MATERIALS AND METHODS: This case-control study involved 156 psychiatric patients and 303 healthy, unrelated, voluntary blood donors...
February 15, 2018: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/29517973/molecular-immunohaematology-round-table-discussions-at-the-aabb-annual-meeting-orlando-2016
#20
Willy A Flegel, Qing Chen, Lilian Castilho, Margaret A Keller, Ellen B Klapper, William J Lane, France Pirenne, Gary Stack, Maryse St-Louis, Christopher A Tormey, Dan A Waxman, Christof Weinstock, Silvano Wendel, Gregory A Denomme
No abstract text is available yet for this article.
February 14, 2018: Blood Transfusion, Trasfusione del Sangue
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