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Blood Transfusion, Trasfusione del Sangue

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https://www.readbyqxmd.com/read/29328904/further-comments-on-high-titre-inhibitors-in-previously-untreated-patients-with-severe-haemophilia-a-receiving-recombinant-or-plasma-derived-factor-viii-a-budget-impact-analysis
#1
LETTER
Andrea Messori, Flora Peyvandi, Sabrina Trippoli, Roberta Palla, Frits R Rosendaal, Pier Mannuccio Mannucci
No abstract text is available yet for this article.
December 22, 2017: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/29328906/importance-of-information-provision-in-the-acceptance-of-blood-donation-criteria-by-the-general-public-in-belgium
#2
Bert Avau, Emmy De Buck, Philippe Vandekerckhove, Veerle Compernolle
BACKGROUND: Blood transfusions save lives, but carry the risk of causing transfusion-transmitted diseases. This risk is limited by strict donor selection criteria, the most controversial being the exclusion of men who had sex with men (MSM). This cross-sectional study investigated knowledge and beliefs of the general public concerning donor exclusion criteria, with emphasis on MSM. MATERIALS AND METHODS: A representative sample of the population of Flanders, Belgium was questioned using a web-based questionnaire...
November 27, 2017: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/29328905/diagnosis-and-care-of-patients-with-mild-haemophilia-practical-recommendations-for-clinical-management
#3
REVIEW
Gary Benson, Günter Auerswald, Gerry Dolan, Anne Duffy, Cedric Hermans, Rolf Ljung, Massimo Morfini, Silva Zupančić Šalek
Mild haemophilia is defined by factor levels between 0.05 and 0.40 IU/mL and is characterised by traumatic bleeds. Major issues associated with mild haemophilia are that it may not present for many years after birth, and that awareness, even within families, may be low. Methodological problems exist in diagnosis, such as inconsistencies in results obtained from different assays used to measure factor levels in mild haemophilia. Advances in genetic testing provide insight into diagnosis as well as the likelihood of inhibitor development, which is not uncommon in patients with mild or moderate haemophilia and can increase morbidity...
November 14, 2017: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/29120704/xvi-convegno-triennale-sui-problemi-clinici-e-sociali-dell-emofilia-e-delle-malattie-emorragiche-congenite-napoli-9-12-novembre-2017
#4
Giovanni Di Minno, Elena Santagostino, Massimo Morfini, Hamisa J Hassan, Angelo C Molinari, Rita C Santoro, Annarita Tagliaferri, Antonio Coppola
No abstract text is available yet for this article.
November 7, 2017: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/29106354/characteristics-of-thawed-pooled-cryoprecipitate-stored-at-refrigerated-temperature-for-24-hours
#5
Esther P Soundar, Meredith Reyes, Laura Korte, Arthur Bracey
BACKGROUND: The need for thawed cryoprecipitate is growing. However, according to current guidelines, the shelf-life of pooled thawed cryoprecipitate at room temperature is limited because of possible bacterial contamination and loss of clotting factor activity. Here we assessed microbial growth and retention of clotting activity in cryoprecipitate stored at 4 °C after thawing to see whether its shelf life could be safely extended. MATERIALS AND METHODS: Pooled thawed cryoprecipitate units (n=10) were maintained at room temperature for 6 hours and then placed at 1-6 °C for 18 hours after thawing...
October 30, 2017: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/29106353/testing-direct-oral-anticoagulants-embedding-in-structured-long-term-care
#6
EDITORIAL
Hugo Ten Cate
No abstract text is available yet for this article.
October 26, 2017: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/29337665/safety-of-intravenous-tranexamic-acid-in-patients-undergoing-majororthopaedic-surgery-a-meta-analysis-of-randomised-controlled-trials
#7
REVIEW
Massimo Franchini, Carlo Mengoli, Marco Marietta, Giuseppe Marano, Stefania Vaglio, Simonetta Pupella, Pier Mannuccio Mannucci, Giancarlo M Liumbruno
Among the various pharmacological options to decrease peri-operative bleeding, tranexamic acid appears to be one of the most interesting. Several trials have consistently documented the efficacy of this synthetic drug in reducing the risk of blood loss and the need for allogeneic blood transfusion in patients undergoing total hip and knee arthroplasty. The safety of intravenous tranexamic acid in major orthopaedic surgery, particularly regarding the risk of venous thromboembolism, was systematically analysed in this review...
January 2018: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/29106355/reply-to-high-titre-inhibitors-in-previously-untreated-patients-with-severe-haemophilia-a-receiving-recombinant-or-plasma-derived-factor-viii-a-budget-impact-analysis-by-messori-et-al
#8
LETTER
Albert Farrugia, Megha Bansal
No abstract text is available yet for this article.
October 3, 2017: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/29059042/k-antigen-blocking-in-a-case-of-haemolytic-disease-of-the-foetus-and-newborn
#9
LETTER
Silvia Manfroi, Claudio Velati
No abstract text is available yet for this article.
October 2017: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/29059041/seroprevalence-of-hepatitis-e-virus-among-blood-donors-in-northern-italy-sondrio-lombardy-determined-by-three-different-assays
#10
Cristina Galli, Laura Fomiatti, Catia Tagliacarne, Claudio Velati, Alessandro R Zanetti, Silvana Castaldi, Luisa Romanò
No abstract text is available yet for this article.
October 2017: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/29053100/ten-years-since-the-last-chikungunya-virus-outbreak-in-italy-history-repeats-itself
#11
EDITORIAL
Giuseppe Marano, Simonetta Pupella, Ilaria Pati, Francesca Masiello, Massimo Franchini, Stefania Vaglio, Claudio Velati, Giancarlo M Liumbruno
No abstract text is available yet for this article.
October 2017: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/28686154/influence-of-red-blood-cell-derived-microparticles-upon-vasoregulation
#12
REVIEW
Ahmed S Said, Allan Doctor
Here we review recent data and the evolving understanding of the role of red blood cell-derived microparticles (RMPs) in normal physiology and in disease progression. Microparticles (MPs) are small membrane vesicles derived from various parent cell types. MPs are produced in response to a variety of stimuli through several cytoskeletal and membrane phospholipid changes. MPs have been investigated as potential biomarkers for multiple disease processes and are thought to have biological effects, most notably in: promotion of coagulation, production and handling of reactive oxygen species, immune modulation, angiogenesis, and in apoptosis...
October 2017: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/28488967/purinergic-control-of-red-blood-cell-metabolism-novel-strategies-to-improve-red-cell-storage-quality
#13
REVIEW
Kaiqi Sun, Angelo D'alessandro, Yang Xia
Transfusion of stored blood is regarded as one of the great advances in modern medicine. However, during storage in the blood bank, red blood cells (RBCs) undergo a series of biochemical and biomechanical changes that affect cell morphology and physiology and potentially impair transfusion safety and efficacy. Despite reassuring evidence from clinical trials, it is universally accepted that the storage lesion(s) results in the altered physiology of long-stored RBCs and helps explain the rapid clearance of up to one-fourth of long-stored RBCs from the recipient's bloodstream at 24 hours after administration...
October 2017: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/28488960/towards-pathogen-inactivation-of-red-blood-cells-and-whole-blood-targeting-viral-dna-rna-design-technologies-and-future-prospects-for-developing-countries
#14
REVIEW
Victor J Drew, Lassina Barro, Jerard Seghatchian, Thierry Burnouf
Over 110 million units of blood are collected yearly. The need for blood products is greater in developing countries, but so is the risk of contracting a transfusion-transmitted infection. Without efficient donor screening/viral testing and validated pathogen inactivation technology, the risk of transfusion-transmitted infections correlates with the infection rate of the donor population. The World Health Organization has published guidelines on good manufacturing practices in an effort to ensure a strong global standard of transfusion and blood product safety...
October 2017: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/28287385/interference-of-direct-oral-anticoagulants-in-haemostasis-assays-high-potential-for-diagnostic-false-positives-and-false-negatives
#15
EDITORIAL
Emmanuel J Favaloro, Giuseppe Lippi
No abstract text is available yet for this article.
October 2017: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/28287382/effect-of-dabigatran-on-a-prothrombinase-based-assay-for-detecting-activated-protein-c-resistance-an-ex-vivo-and-in-vitro-study-in-normal-subjects-and-factor-v-leiden-carriers
#16
Gianluca Gessoni, Sara Valverde, Letizia Valle, Pierpaolo Caruso, Francesca Gessoni, Roberto Valle
BACKGROUND: The aim of this study was to evaluate ex vivo and in vitro interference of a direct factor IIa inhibitor, dabigatran, on a prothrombinase-based assay to detect activated protein C resistance. MATERIALS AND METHODS: An ex vivo study was performed in six heterozygous factor V Leiden carriers and 12 normal subjects without the factor V Leiden mutation who were treated with dabigatran. An in vitro study was also performed considering 12 plasma samples (six from normal subjects and six from heterozygous factor V Leiden carriers) spiked with dabigatran...
October 2017: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/27893359/collection-of-umbilical-cord-blood-for-banking-collection-rate-and-factors-influencing-collection
#17
LETTER
Veronica Valle, Maria Screnci, Emilia Murgi, Martina Capozzi, Gabriella Girelli
No abstract text is available yet for this article.
October 2017: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/27893354/summary-report-of-the-first-international-conference-on-inhibitors-in-haemophilia-a
#18
Sebastien Lacroix-Desmazes, David W Scott, Jenny Goudemand, Marijke Van Den Berg, Michael Makris, Alice S Van Velzen, Elena Santagostino, David Lillicrap, Frits R Rosendaal, Anneliese Hilger, Zuben E Sauna, Johannes Oldenburg, Lorenzo Mantovani, M Elisa Mancuso, Craig Kessler, Charles R M Hay, Paul Knoebl, Giovanni Di Minno, Keith Hoots, Amanda Bok, Mark Brooker, Erica Buoso, Pier Mannuccio Mannucci, Flora Peyvandi
No abstract text is available yet for this article.
October 2017: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/27723450/fully-automated-clinical-grade-bone-marrow-processing-a-single-centre-experience
#19
Benedetta Mazzanti, Serena Urbani, Simone Dal Pozzo, Paola Bufano, Lara Ballerini, Alessia Gelli, Irene Sodi, Irene Donnini, Massimo Di Gioia, Stefano Guidi, Julien Camisani, Riccardo Saccardi
BACKGROUND: Clinical grade processing of harvested bone marrow is required in various clinical situations, particularly in the management of ABO mismatching in allogeneic haematopoietic stem cell transplantation (HSCT) and in regenerative medicine. MATERIAL AND METHODS: We report a single-centre experience using a fully automated, clinical grade, closed system (Sepax, Biosafe, Switzerland). From 2003 to 2015, 125 procedures were performed in our laboratory, including buffy-coat production for HSCT (n=58), regenerative medicine in an orthopaedic setting (n=54) and density-gradient separation in a trial for treatment of critical limb ischaemia (n=13)...
October 2017: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/27723449/selection-strategies-for-newly-registered-blood-donors-in-european-countries
#20
Ryanne W Lieshout-Krikke, Dragoslav Domanovic, Wim De Kort, Wolfgang Mayr, Giancarlo M Liumbruno, Simonetta Pupella, Johann Kurz, Folke Knutson, Sheila Maclennan, Gilles Folléa
BACKGROUND: Two selection strategies for newly-registered blood donors are available: a single-visit selection called the standard selection procedure (SSP), and a two-stage selection named predonation and donation screening (PDS). This study reviews the selection strategies for newly-registered donors currently applied in European countries. MATERIAL AND METHODS: We collected data on donor selection procedures, blood donation, laboratory screening and HIV, HCV and HBV positive donors/donations from 2010 to 2013 in 30 European countries by using questionnaires...
October 2017: Blood Transfusion, Trasfusione del Sangue
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