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Journal of Zhejiang University. Science. B

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https://www.readbyqxmd.com/read/28378574/efficacy-of-vaccination-and-nisin-z-treatments-to-eliminate-intramammary-staphylococcus-aureus-infection-in-lactating-cows
#1
Ran Guan, Jun-Qiang Wu, Wei Xu, Xiao-Yan Su, Song-Hua Hu
This study evaluated the effect of a Staphylococcus aureus bacterin and nisin on bovine subclinical mastitis. A total of 75 Holstein subclinically mastitic cows were randomly allocated to three groups with 25 cows per group. In group I, an intramammary infusion of nisin Z at a dose of 2.50×10(6) IU was carried out once daily for three days, and an autogenous S. aureus bacterin was inoculated into the supramammary lymph node one week before and one week after nisin treatment. In group II, nisin was administered in the same way as in group I, but no bacterin was inoculated...
2017: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/28378573/bispectral-index-guided-sedation-in-transfemoral-transcatheter-aortic-valve-implantation-a-retrospective-control-study
#2
Wei He, Rong-Rong Huang, Qing-Yu Shi, Xian-Bao Liu, Jian-An Wang, Min Yan
OBJECTIVE: Transcatheter aortic valve implantation (TAVI) is a minimally invasive therapy for elderly patients with severe aortic valve stenosis who were refused surgical aortic valve replacement because of the high perioperative risk. Traditionally, this procedure has been done under general anesthesia, but more recently local anesthesia and sedation have become popular. This research assessed the effectiveness of transfemoral TAVI under bispectral index (BIS)-guided sedation. METHODS: In this single-center retrospective control analysis, clinical data, including demographic characteristics, echocardiography, periprocedural data, and main complications, were collected and assessed in 113 patients undergoing TAVI through the femoral artery under general anesthesia (GA group, n=36) and under BIS-guided sedation (SED group, n=77)...
2017: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/28378572/effect-of-compatible-herbs-on-the-pharmacokinetics-of-effective-components-of-panax-notoginseng-in-fufang-xueshuantong-capsule
#3
Huan-Huan Pang, Meng-Yi Li, Yuan Wang, Min-Ke Tang, Chang-Hua Ma, Jian-Mei Huang
Fufang Xueshuantong (FXT) is a well-known Chinese herbal formula which has been used to treat cardiovascular and ophthalmic diseases, especially diabetic retinopathy. Panax notoginseng (Burkill) F.H. Chen (PN) is the main herb of FXT, whose major bioactive constituents are ginsenosides. However, the scientific basis of the compatibility of FXT is still ambiguous. The present study investigated the scientific basis of the compatibility of FXT by comparing the pharmacokinetics of marker compounds after oral administrations of PN and FXT...
2017: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/28378571/protein-tyrosine-phosphatase-1b-expression-contributes-to-the-development-of-breast-cancer
#4
Shi-Chong Liao, Jin-Xin Li, Li Yu, Sheng-Rong Sun
The protein tyrosine phosphatase 1B (PTP1B) is an important regulator of metabolism. The relationship between PTP1B and tumors is quite complex. The purpose of this study is to explore the expression pattern and role of PTP1B in breast cancer. The expression of PTP1B was detected in 67 samples of breast cancer tissue by Western blot. Cell growth assay, Transwell migration assay, and Scratch motility assay were used to examine the proliferation and migration of MCF-7 with and without PTP1B. The total levels and phosphorylated levels of signal transduction and activator of transcription 3 (STAT3) and the expression of C-C motif chemokine ligand 5 (CCL5) were also examined by Western blot...
2017: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/28378570/evaluation-of-the-antioxidant-property-and-effects-in-caenorhabditis-elegans-of-xiangxi-flavor-vinegar-a-hunan-local-traditional-vinegar
#5
Run-Ting Huang, Qing Huang, Gen-Liang Wu, Chun-Guang Chen, Zong-Jun Li
Xiangxi flavor vinegar (XV) is one of Hunan Province's traditional fermented vinegars. It is produced from herb, rice, and spring water with spontaneous liquid-state fermentation techniques. In this study, we investigated the antioxidant property of XV by analyzing its antioxidant compounds, its free radical scavenging property in vitro and in vivo, and its effects on antioxidant enzyme activity and apoptosis in Caenorhabditis elegans. The results showed that XV is rich in antioxidants. In particular, ligustrazine reached 6...
2017: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/28378569/porcine-circovirus-type-2-capsid-protein-induces-unfolded-protein-response-with-subsequent-activation-of-apoptosis
#6
Ying-Shan Zhou, Yuan-Xing Gu, Bao-Zhu Qi, Yi-Kai Zhang, Xiao-Liang Li, Wei-Huan Fang
Porcine circovirus type 2 (PCV2) has recently been reported to elicit the unfolded protein response (UPR) via activation of the PERK/eIF2α (RNA-activated protein kinase-like endoplasmic reticulum (ER) kinase/eukaryotic initiation factor 2α) pathway. This study attempted to examine which viral protein might be involved in inducing UPR and whether this cellular event would lead to apoptosis of the cells expressing the viral protein. By transient expression, we found that both replicase (Rep) and capsid (Cap) proteins of PCV2 could induce ER stress as shown by increased phosphorylation of PERK with subsequent activation of the eIF2α-ATF4 (activating transcription factor 4)-CHOP (CCAAT/enhancer-binding protein homologous protein) axis...
2017: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/28378568/rapid-prototyping-technology-and-its-application-in-bone-tissue-engineering
#7
Bo Yuan, Sheng-Yuan Zhou, Xiong-Sheng Chen
Bone defects arising from a variety of reasons cannot be treated effectively without bone tissue reconstruction. Autografts and allografts have been used in clinical application for some time, but they have disadvantages. With the inherent drawback in the precision and reproducibility of conventional scaffold fabrication techniques, the results of bone surgery may not be ideal. This is despite the introduction of bone tissue engineering which provides a powerful approach for bone repair. Rapid prototyping technologies have emerged as an alternative and have been widely used in bone tissue engineering, enhancing bone tissue regeneration in terms of mechanical strength, pore geometry, and bioactive factors, and overcoming some of the disadvantages of conventional technologies...
2017: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/28378567/insights-into-the-microbial-diversity-and-community-dynamics-of-chinese-traditional-fermented-foods-from-using-high-throughput-sequencing-approaches
#8
Guo-Qing He, Tong-Jie Liu, Faizan A Sadiq, Jing-Si Gu, Guo-Hua Zhang
Chinese traditional fermented foods have a very long history dating back thousands of years and have become an indispensable part of Chinese dietary culture. A plethora of research has been conducted to unravel the composition and dynamics of microbial consortia associated with Chinese traditional fermented foods using culture-dependent as well as culture-independent methods, like different high-throughput sequencing (HTS) techniques. These HTS techniques enable us to understand the relationship between a food product and its microbes to a greater extent than ever before...
2017: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/28378566/immune-response-of-t-cells-during-herpes-simplex-virus-type-1-hsv-1-infection
#9
Jie Zhang, Huan Liu, Bin Wei
Herpes simplex virus type 1 (HSV-1), a neurotropic member of the alphaherpes virus family, is among the most prevalent and successful human pathogens. HSV-1 can cause serious diseases at every stage of life including fatal disseminated disease in newborns, cold sores, eye disease, and fatal encephalitis in adults. HSV-1 infection can trigger rapid immune responses, and efficient inhibition and clearance of HSV-1 infection rely on both the innate and adaptive immune responses of the host. Multiple strategies have been used to restrict host innate immune responses by HSV-1 to facilitate its infection in host cells...
2017: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/28271663/vascular-complications-following-prophylactic-balloon-occlusion-of-the-internal-iliac-arteries-resolved-by-successful-interventional-thrombolysis-in-a-patient-with-morbidly-adherent-placenta
#10
Ning Zhang, Wei-Hua Lou, Xue-Bin Zhang, Jia-Ning Fu, Yun-Yan Chen, Zhi-Guo Zhuang, Jian-Hua Lin
The increasing incidence of morbidly adherent placenta (MAP) is placing women at a higher risk of life-threatening massive hemorrhage. The involvement of interventional radiology to manage this complex condition by performing prophylactic iliac artery balloon occlusion has been reported recently. However, the effectiveness and safety of this technique have not been fully determined. Here we report the case of a 25-year-old woman with placenta increta with preemptive bilateral internal iliac artery balloons who had external iliac artery thrombosis detected by computed tomography angiography (CTA) 72 h post cesarean section...
2017: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/28271662/effects-of-pre-pregnancy-body-mass-index-and-gestational-weight-gain-on-neonatal-birth-weight
#11
Meng-Kai Du, Li-Ya Ge, Meng-Lin Zhou, Jun Ying, Fan Qu, Min-Yue Dong, Dan-Qing Chen
To evaluate the effects of maternal pre-pregnancy body mass index (pre-BMI) and gestational weight gain (GWG) on neonatal birth weight (NBW) in the population of Chinese healthy pregnant women, attempting to guide weight control in pregnancy. A retrospective cohort study of 3772 Chinese women was conducted. The population was stratified by maternal pre-BMI categories as underweight (<18.5 kg/m(2)), normal weight (18.5-23.9 kg/m(2)), overweight (24.0-27.9 kg/m(2)), and obesity (≥28.0 kg/m(2)). The NBW differences were tested among the four groups, and then deeper associations among maternal pre-BMI, GWG, and NBW were investigated by multivariate analysis...
2017: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/28271661/human-papillomavirus-hpv-e6-e7-mrna-detection-in-cervical-exfoliated-cells-a-potential-triage-for-hpv-positive-women
#12
Ye-Li Yao, Qi-Fang Tian, Bei Cheng, Yi-Fan Cheng, Jing Ye, Wei-Guo Lu
Cytology triage has been generally recommended for human papillomavirus (HPV)-positive women, but is highly dependent on well-trained cytologists. The present study was designed to explore whether HPV E6/E7 mRNA detection in cervical exfoliated cells can be a potential triage for HPV-positive women from a clinic-based population. Both the primary HPV testing and Papanicolaou (Pap) test were performed on all eligible HPV-positive women. HPV E6/E7 mRNA was detected by QuantiVirus(®) HPV E6/E7 mRNA assay in cervical exfoliated cells...
2017: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/28271660/prognostic-value-of-human-papillomavirus-16-18-genotyping-in-low-grade-cervical-lesions-preceded-by-mildly-abnormal-cytology
#13
Jing Ye, Bei Cheng, Yi-Fan Cheng, Ye-Li Yao, Xing Xie, Wei-Guo Lu, Xiao-Dong Cheng
Histological low-grade squamous intraepithelial lesion/cervical intraepithelial neoplasia grade 1 (LSIL/CIN1) preceded by normal or mildly abnormal cytology is recommended for conservative follow-up, with no separated management. In this study, we assessed the triage value of human papillomavirus (HPV) 16/18 genotyping in 273 patients with LSIL/CIN1. HPV16/18 genotyping was performed at baseline and follow-up was at 6-monthly intervals for up to 2 years. At each follow-up, women positive for cytology or high-risk HPV (hrHPV) were referred for colposcopy...
2017: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/28271659/effects-of-electroacupuncture-at-2-and-100-hz-on-rat-type-2-diabetic-neuropathic-pain-and-hyperalgesia-related-protein-expression-in-the-dorsal-root-ganglion
#14
Xiao-Fen He, Jun-Jun Wei, Sheng-Yun Shou, Jian-Qiao Fang, Yong-Liang Jiang
OBJECTIVE: To investigate the analgesic effects of electroacupuncture (EA) at 2 and 100 Hz on type 2 diabetic neuropathic pain (DNP) and on the expressions of the P2X3 receptor and calcitonin gene-related peptide (CGRP) in the dorsal root ganglion (DRG). METHODS: Rat type 2 DNP was induced by a high calorie and high sugar diet fed for 7 weeks, plus a single intraperitoneal injection of streptozotocin (STZ) after 5 weeks. EA at 2 and 100 Hz was carried out once every day after 7 weeks for 7 consecutive days...
2017: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/28271658/integrating-acupuncture-are-there-positive-health-outcomes-for-women
#15
Nicola Robinson
The key health issues for women tend to be primarily associated with the female reproductive system. There are also other gender priorities and consequences associated with ageing, which require effective interventions. Acupuncture is used worldwide and its evidence base is increasing on both mechanisms of action and its effectiveness in clinical care. Although acupuncture may be a valuable addition to healthcare for some conditions, it is rarely fully integrated into mainstream Western medicine clinical practice...
2017: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/28271657/dna-damage-response-is-hijacked-by-human-papillomaviruses-to-complete-their-life-cycle
#16
Shi-Yuan Hong
The DNA damage response (DDR) is activated when DNA is altered by intrinsic or extrinsic agents. This pathway is a complex signaling network and plays important roles in genome stability, tumor transformation, and cell cycle regulation. Human papillomaviruses (HPVs) are the main etiological agents of cervical cancer. Cervical cancer ranks as the fourth most common cancer among women and the second most frequent cause of cancer-related death worldwide. Over 200 types of HPVs have been identified and about one third of these infect the genital tract...
2017: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/28271656/biological-activity-and-toxicity-of-the-chinese-herb-magnolia-officinalis-rehder-e-wilson-houpo-and-its-constituents
#17
Mélanie Poivre, Pierre Duez
Traditional Chinese herbal drugs have been used for thousands of years in Chinese pharmacopoeia. The bark of Magnolia officinalis Rehder & E. Wilson, known under the pinyin name "Houpo", has been traditionally used in Chinese and Japanese medicines for the treatment of anxiety, asthma, depression, gastrointestinal disorders, headache, and more. Moreover, Magnolia bark extract is a major constituent of currently marketed dietary supplements and cosmetic products. Much pharmacological activity has been reported for this herb and its major compounds, notably antioxidant, anti-inflammatory, antibiotic and antispasmodic effects...
2017: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/28271655/use-of-electroacupuncture-and-transcutaneous-electrical-acupoint-stimulation-in-reproductive-medicine-a-group-consensus
#18
Fan Qu, Rong Li, Wei Sun, Ge Lin, Rong Zhang, Jing Yang, Li Tian, Guo-Gang Xing, Hui Jiang, Fei Gong, Xiao-Yan Liang, Yan Meng, Jia-Yin Liu, Li-Ying Zhou, Shu-Yu Wang, Yan Wu, Yi-Jing He, Jia-Yu Ye, Song-Ping Han, Ji-Sheng Han
With the rapid development of assisted reproductive technology, various reproductive disorders have been effectively addressed. Acupuncture-like therapies, including electroacupuncture (EA) and transcutaneous electrical acupoint stimulation (TEAS), become more popular world-wide. Increasing evidence has demonstrated that EA and TEAS are effective in treating gynecological disorders, especially infertility. This present paper describes how to select acupoints for the treatment of infertility from the view of theories of traditional Chinese medicine and how to determine critical parameters of electric pulses of EA/TEAS based on results from animal and clinical studies...
2017: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/28271654/women-s-health-and-chinese-integrative-medicine
#19
Fan Qu, Fang-Fang Wang, Nicola Robinson, Paul J Hardiman
Researchers in the fields of obstetrics, gynecology, and Chinese integrative medicine (CIM) were invited to share their perspectives on the most recent studies.
2017: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/28124845/identification-of-neuron-related-genes-for-cell-therapy-of-neurological-disorders-by-network-analysis
#20
Li-Ning Su, Xiao-Qing Song, Hui-Ping Wei, Hai-Feng Yin
Bone mesenchymal stem cells (BMSCs) differentiated into neurons have been widely proposed for use in cell therapy of many neurological disorders. It is therefore important to understand the molecular mechanisms underlying this differentiation. We screened differentially expressed genes between immature neural tissues and untreated BMSCs to identify the genes responsible for neuronal differentiation from BMSCs. GSE68243 gene microarray data of rat BMSCs and GSE18860 gene microarray data of rat neurons were received from the Gene Expression Omnibus database...
2017: Journal of Zhejiang University. Science. B
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