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Journal of Zhejiang University. Science. B

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https://www.readbyqxmd.com/read/29732752/avian-influenza-viruses-aivs-h9n2-are-in-the-course-of-reassorting-into-novel-aivs
#1
Hui-Ping Chang, Li Peng, Liang Chen, Lu-Fang Jiang, Zhi-Jie Zhang, Cheng-Long Xiong, Gen-Ming Zhao, Yue Chen, Qing-Wu Jiang
In 2013, two episodes of influenza emerged in China and caused worldwide concern. A new H7N9 avian influenza virus (AIV) first appeared in China on February 19, 2013. By August 31, 2013, the virus had spread to ten provinces and two metropolitan cities. Of 134 patients with H7N9 influenza, 45 died. From then on, epidemics emerged sporadically in China and resulted in several victims. On November 30, 2013, a 73-year-old woman presented with an influenza-like illness. She developed multiple organ failure and died 9 d after the onset of disease...
May 2018: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/29732751/neurological-responses-of-embryo-larval-zebrafish-to-short-term-sediment-exposure-to-decabromodiphenylethane
#2
Mei-Qing Jin, Dong Zhang, Ying Zhang, Shan-Shan Zhou, Xian-Ting Lu, Hong-Ting Zhao
Decabromodiphenylethane (DBDPE) has been widely used as an alternative flame retardant due to the restriction or phase-out of traditional polybrominated diphenyl ethers (PBDEs), and is of increasing concern regarding its ubiquity, persistence, and potential adverse effects. In the present study, the toxicological effects of DBDPE were evaluated using zebrafish as an in vivo model. Upon being exposed to DBDPE-polluted sediments for a short term, it was found that the mortality and malformation of zebrafish (including edema, bent notochord, and bent tail) were not affected even at the highest concentration tested (1000...
May 2018: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/29732750/age-related-changes-of-yolk-precursor-formation-in-the-liver-of-laying-hens
#3
Xing-Ting Liu, Xin Lin, Yu-Ling Mi, Wei-Dong Zeng, Cai-Qiao Zhang
A rapid decline in egg production of laying hens begins after 480 d of age. Such a rapid decrease results predominantly from the ovarian aging, accompanied by endocrine changes, decreased yolk synthesis and accumulation, and the reduction in follicles selected into the preovulatory hierarchy. In this study, hens at 90, 150, 280, and 580 d old (D90, D150, D280, and D580, respectively) were compared for yolk precursor formation in the liver to elucidate effects of aging on laying performance. The results showed that liver lipid synthesis increased remarkably in hens from D90 to D150, but decreased sharply at D580 as indicated by the changes in triglyceride (TG) levels...
May 2018: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/29732749/creation-of-a-rabbit-model-for-intrauterine-adhesions-using-electrothermal-injury
#4
Xin-Xin Xu, Lian-Bao Cao, Zhe Wang, Zhen Xu, Bing-Qian Zhang, She-Ling Wu, Sha-Sha Qi, Lei Yan, Zi-Jiang Chen
The pathogenesis and therapeutic treatment of intrauterine adhesions (IUAs) remain unsolved, highlighting the need for stable and effective experimental animal models. In this study, uterine electrocoagulation of twenty-one female New Zealand White rabbits was carried out to establish an IUA model. As rabbits have two completely separate uterine horns, each rabbit had its own internal control: one uterine horn was given an electrothermal injury (Group A, n=21), and the contralateral uterine horn received no treatment and served as the control (Group B, n=21)...
May 2018: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/29732748/surface-characteristics-and-mechanical-behavior-of-retrieved-orthodontic-microimplants
#5
Lu Lu, Hyo-Sang Park
OBJECTIVES: To observe the surface characteristics and mechanical behavior of retrieved microimplants under clinically simulating experimental conditions and to investigate the feasibility of reuse of microimplants. MATERIALS AND METHODS: The microimplants, inserted at different angles, were retrieved from the patients (RMIP) and the artificial bone (RMIA). Surface characteristics, including morphologic changes of tips and thread edges, length reduction, and surface compositional variation, were evaluated using a field emission scanning electron microscope, a stereoscopic microscope, and energy-dispersive X-ray spectroscopy, respectively...
May 2018: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/29732747/antibacterial-and-anti-biofilm-activity-of-the-lipid-extract-from-mantidis-ootheca-on-pseudomonas-aeruginosa
#6
Wen-Dong Wang, Nan-Nan Zhang, Warren Chanda, Min Liu, Syed Riaz Ud Din, Yun-Peng Diao, Lei Liu, Jing Cao, Xiao-Li Wang, Xing-Yun Li, An-Hong Ning, Min Huang, Min-Tao Zhong
The aim of this study is to assess the antibacterial and anti-biofilm properties of the lipid extract from Mantidis ootheca against the gentamycin resistant Pseudomonas aeruginosa. The chemical composition of the lipid extract and its relative proportion were determined using the technique of gas chromatography coupled with mass spectrometry (GC-MS). Antibacterial susceptibility tests were performed using a disc diffusion assay and the minimum inhibition concentration (MIC) was determined by way of the agar dilution method...
May 2018: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/29732746/american-european-and-chinese-practice-guidelines-or-consensuses-of-polycystic-ovary-syndrome-a-comparative-analysis
#7
Fang-Fang Wang, Jie-Xue Pan, Yan Wu, Yu-Hang Zhu, Paul J Hardiman, Fan Qu
Polycystic ovary syndrome (PCOS) is the most common metabolic and endocrine disorder in women. However, there is no agreement concerning how to diagnose and treat PCOS worldwide. Three practice guidelines or consensuses, including consensus from the European Society of Human Reproduction and Embryology (ESHRE)/the American Society for Reproductive Medicine (ASRM) in Rotterdam, diagnosis criteria and consensus in China, and clinical practice guideline from the Endocrine Society (ES) in the United States are widely recognized...
May 2018: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/29732745/combining-fragmented-qrs-and-timi-score-for-predicting-in-hospital-short-term-prognosis-after-acute-myocardial-infarction
#8
Qin-Hui Sheng, Chih Chi Hsu, Jian-Ping Li, Tao Hong, Yong Huo
Acute myocardial infarction (AMI) has a high mortality rate and poor prognosis for patients. The primary causes of death are arrhythmia and heart failure. For patients admitted because of myocardial infarction, various risk evaluations are initiated to foresee possible complications. The thrombolysis in myocardial infarction (TIMI) risk score, which can be used to predict the prognosis and the need for revascularisation, is the most convenient and commonly used system, but is inadequate for AMI patients on admittance...
May 2018: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/29732744/early-diagnosis-of-acute-kidney-injury-in-aged-patients-undergoing-percutaneous-coronary-intervention
#9
Hong-Hua Ye, Gen Shen, Qun Luo, Fang-Fang Zhou, Xiao-Ling Xie, Chun-Yan Wang, Li-Na Han
In aged patients, acute kidney injury (AKI) is a common clinical complication after percutaneous coronary intervention (PCI), highlighting the need for timely and certain diagnosis of this disease. A single centre, nested case-control study was conducted, which assessed the usefulness of urinary liver-type fatty acid-binding protein (uL-FABP), neutrophil gelatinase-associated lipocalin (uNGAL), and kidney injury molecule-1 (uKIM-1) for early detection of AKI. One hundred and thirty-two patients at or over 60 years old undergoing PCI were included...
May 2018: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/29732743/regulation-of-autophagy-by-tea-polyphenols-in-diabetic-cardiomyopathy
#10
Hui Zhou, Yan Chen, Shu-Wei Huang, Peng-Fei Hu, Li-Jiang Tang
OBJECTIVE: To investigate the effect of tea polyphenols on cardiac function in rats with diabetic cardiomyopathy, and the mechanism by which tea polyphenols regulate autophagy in diabetic cardiomyopathy. METHODS: Sixty Sprague-Dawley (SD) rats were randomly divided into six groups: a normal control group (NC), an obesity group (OB), a diabetic cardiomyopathy group (DCM), a tea polyphenol group (TP), an obesity tea polyphenol treatment group (OB-TP), and a diabetic cardiomyopathy tea polyphenol treatment group (DCM-TP)...
May 2018: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/29770647/neuromodulation-for-tinnitus-treatment-an-overview-of-invasive-and-non-invasive-techniques
#11
REVIEW
Nicole Peter, Tobias Kleinjung
Tinnitus is defined as a perception of sound without any external sound source. Chronic tinnitus is a frequent condition that can affect the quality of life. So far, no causal cure for tinnitus has been documented, and most pharmacologic and psychosomatic treatment modalities aim to diminish tinnitus' impact on the quality of life. Neuromodulation, a novel therapeutic modality, which aims at alternating nerve activity through a targeted delivery of a stimulus, has emerged as a potential option in tinnitus treatment...
March 12, 2018: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/29616508/an-efficacy-analysis-of-anti-vascular-endothelial-growth-factor-therapy-for-choroidal-neovascularization-secondary-to-multifocal-choroiditis-and-comparison-with-wet-age-related-macular-degeneration
#12
Lei Feng, Jiang-Hua Hu, Jie Chen, Xin Xie
OBJECTIVE: To evaluate the effect of anti-vascular endothelial growth factor (VEGF) on juxtafoveal choroidal neovascularization (CNV) secondary to multifocal choroiditis (MFC) and wet age-related macular degeneration (AMD). METHODS: In this retrospective, comparative study, 20 unique eyes with CNV were divided into two groups: 10 patients affected by MFC and 10 patients diagnosed with wet AMD. They all received local intravitreal (IVT) injections of ranibizumab, with 6 months of follow-up...
2018: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/29616507/physical-and-chemical-characteristics-of-pm-2-5-and-its-toxicity-to-human-bronchial-cells-beas-2b-in-the-winter-and-summer
#13
Hui-Hui Zhang, Zheng Li, Yu Liu, Ping Xinag, Xin-Yi Cui, Hui Ye, Bao-Lan Hu, Li-Ping Lou
With the increasing occurrence of haze during the summer, the physicochemical characteristics and toxicity differences in PM2.5 in different seasons are of great concern. Hangzhou is located in an area that has a subtropical monsoon climate where the humidity is very high during both the summer and winter. However, there are limited studies on the seasonal differences in PM2.5 in these weather conditions. In this test, PM2.5 samples were collected in the winter and summer, the morphology and chemical composition of PM2...
2018: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/29616506/effects-of-different-external-carbon-sources-and-electron-acceptors-on-interactions-between-denitrification-and-phosphorus-removal-in-biological-nutrient-removal-processes
#14
Xiang Hu, Dominika Sobotka, Krzysztof Czerwionka, Qi Zhou, Li Xie, Jacek Makinia
The effects of two different external carbon sources (acetate and ethanol) and electron acceptors (dissolved oxygen, nitrate, and nitrite) were investigated under aerobic and anoxic conditions with non-acclimated process biomass from a full-scale biological nutrient removal-activated sludge system. When acetate was added as an external carbon source, phosphate release was observed even in the presence of electron acceptors. The release rates were 1.7, 7.8, and 3.5 mg P/(g MLVSS·h) (MLVSS: mixed liquor volatile suspended solids), respectively, for dissolved oxygen, nitrate, and nitrite...
2018: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/29616505/network-analysis-of-micrornas-transcription-factors-and-target-genes-involved-in-axon-regeneration
#15
Li-Ning Su, Xiao-Qing Song, Zhan-Xia Xue, Chen-Qing Zheng, Hai-Feng Yin, Hui-Ping Wei
Axon regeneration is crucial for recovery from neurological diseases. Numerous studies have identified several genes, microRNAs (miRNAs), and transcription factors (TFs) that influence axon regeneration. However, the regulatory networks involved have not been fully elucidated. In the present study, we analyzed a regulatory network of 51 miRNAs, 27 TFs, and 59 target genes, which is involved in axon regeneration. We identified 359 pairs of feed-forward loops (FFLs), seven important genes (Nap1l1, Arhgef12, Sema6d, Akt3, Trim2, Rab11fip2, and Rps6ka3), six important miRNAs (hsa-miR-204-5p, hsa-miR-124-3p, hsa-miR-26a-5p, hsa-miR-16-5p, hsa-miR-17-5p, and hsa-miR-15b-5p), and eight important TFs (Smada2, Fli1, Wt1, Sp6, Sp3, Smad4, Smad5, and Creb1), which appear to play an important role in axon regeneration...
2018: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/29616504/biosynthesis-of-r-2-hydroxy-3-phenylpropionic-acid-using-whole-recombinant-escherichia-coli-cells-in-an-aqueous-n-octane-biphasic-system
#16
Yi-Bo Zhu, Yan Xu, Li-Mei Wang, Bin Qi
(R)-2-hydroxy-3-phenylpropionic acid (PLA) is an ideal antimicrobial compound with broad-spectrum activity against a wide range of Gram-positive bacteria, some Gram-negative bacteria, and fungi. We studied the bioconversion of phenylpyruvate (PPA) to PLA using whole recombinant Escherichia coli cells in a series of buffer/organic solvent systems. Octane was found to be the best organic solvent. The optimum volume ratio of the water phase to the n-octane phase, conversion temperature, substrate concentration, and cell concentration were 6:4, 40 °C, 12...
2018: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/29616503/a-novel-endogenous-badnavirus-exists-in-alhagi-sparsifolia
#17
Yong-Chao Li, Jian-Guo Shen, Guo-Huan Zhao, Qin Yao, Wei-Min Li
We report the recovery of a 7068-nt viral sequence from the "viral fossils" embedded in the genome of Alhagi sparsifolia, a typical desert plant. Although the full viral genome remains to be completed, the putative genome structure, the deduced amino acids and phylogenetic analysis unambiguously demonstrate that this viral sequence represents a novel species of the genus Badnavirus. The putative virus is tentatively termed Alhagi bacilliform virus (ABV). Southern blotting and inverse polymerase chain reaction (PCR) data indicate that the ABV-related sequence is integrated into the A...
2018: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/29616502/pgl3-is-required-for-chlorophyll-synthesis-and-impacts-leaf-senescence-in-rice
#18
Jing Ye, Yao-Long Yang, Xing-Hua Wei, Xiao-Jun Niu, Shan Wang, Qun Xu, Xiao-Ping Yuan, Han-Yong Yu, Yi-Ping Wang, Yue Feng, Shu Wang
Rice leaf color mutants play a great role in research about the formation and development of chloroplasts and the genetic mechanism of the chlorophyll (Chl) metabolism pathway. pgl3 is a rice leaf color mutant derived from Xiushui11 (Oryza sativa L. spp. japonica), treated with ethyl methane sulfonate (EMS). The mutant exhibited a pale-green leaf (pgl) phenotype throughout the whole development as well as reduced grain quality. Map-based cloning of PGL3 revealed that it encodes the chloroplast signal recognition particle 43 kDa protein (cpSRP43)...
2018: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/29616501/effectiveness-of-omega-3-polyunsaturated-fatty-acids-against-microbial-pathogens
#19
Warren Chanda, Thomson P Joseph, Xue-Fang Guo, Wen-Dong Wang, Min Liu, Miza S Vuai, Arshad A Padhiar, Min-Tao Zhong
Microorganisms provide both beneficial and harmful effects to human beings. Beneficial effects come from the symbiotic relationship that exists between humans and microbiota, but then several human illnesses have turned some friendly microbes into opportunistic pathogens, causing several microbial-related diseases. Various efforts have been made to create and utilize antimicrobial agents in the treatment and prevention of these infections, but such efforts have been hampered by the emergence of antimicrobial resistance...
2018: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/29504317/supplementation-with-turmeric-residue-increased-survival-of-the-chinese-soft-shelled-turtle-pelodiscus-sinensis-under-high-ambient-temperatures
#20
Yong Chen, Yi-Fan Zhang, Hao-Cheng Qian, Jing-Liang Wang, Zhe Chen, Jose M Ordovas, Chao-Qiang Lai, Li-Rong Shen
Turmeric residue (TR), containing residual levels of curcumin, is a solid by-product waste generated after the extraction and separation of curcumin from turmeric root. A feeding trial was conducted to evaluate the effects of TR on the survival of Chinese soft-shelled turtles (SSTs), Pelodiscus sinensis, under a high ambient temperature. A total of 320 female SSTs were assigned randomly to two diets: basal diet (the control group, n=160) and an interventional diet supplemented with 10% TR (the TR group, n=160)...
2018: Journal of Zhejiang University. Science. B
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