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Journal of Zhejiang University. Science. B

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https://www.readbyqxmd.com/read/29971995/nucleocapsid-protein-from-porcine-epidemic-diarrhea-virus-isolates-can-antagonize-interferon-%C3%AE-production-by-blocking-the-nuclear-factor-%C3%AE%C2%BAb-nuclear-translocation
#1
Ying Shan, Zi-Qi Liu, Guo-Wei Li, Cong Chen, Hao Luo, Ya-Jie Liu, Xun-Hui Zhuo, Xing-Fen Shi, Wei-Huan Fang, Xiao-Liang Li
Porcine epidemic diarrhea virus (PEDV) is a highly infectious pathogen that can cause severe diseases in pigs and result in enormous economic losses in the worldwide swine industry. Previous studies revealed that PEDV exhibits an obvious capacity for modulating interferon (IFN) signaling or expression. The newly discovered type III IFN, which plays a crucial role in antiviral immunity, has strong antiviral activity against PEDV proliferation in IPEC-J2 cells. In this study, we aimed to investigate the effect of PEDV nucleocapsid (N) protein on type III IFN-λ...
July 2018: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/29971994/stability-of-a-type-2-diabetes-rat-model-induced-by-high-fat-diet-feeding-with-low-dose-streptozotocin-injection
#2
Xiao-Xuan Guo, Yong Wang, Kai Wang, Bao-Ping Ji, Feng Zhou
OBJECTIVE: The present study aims at determining the stability of a popular type 2 diabetes rat model induced by a high-fat diet combined with a low-dose streptozotocin injection. METHODS: Wistar rats were fed with a high-fat diet for 8 weeks followed by a one-time injection of 25 or 35 mg/kg streptozotocin to induce type 2 diabetes. Then the diabetic rats were fed with regular diet/high-fat diet for 4 weeks. Changes in biochemical parameters were monitored during the 4 weeks...
July 2018: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/29971993/methodology-and-cohort-profile-for-the-hangzhou-lumbar-spine-study-a-study-focusing-on-back-health-in-a-chinese-population
#3
Xiao-Jian Hu, Lun-Hao Chen, Michele C Battié, Yue Wang
Back pain is a worldwide health problem, adding a tremendous burden to modern societies. However, little information on back health is available in China, even though a quarter of the world's population is Chinese. To enhance knowledge in this area, we designed and initiated the Hangzhou Lumbar Spine Study, which is a cross-sectional study of a general sample of mainland Chinese with focusing on disc degeneration, Modic changes, endplate lesions, and back pain. The study consists of a structured questionnaire to measure back pain history and lifetime exposure to suspected risk factors, magnetic resonance imaging of the lumbar spine, bone mineral density study of the spine and hip, and DNA sample analysis...
July 2018: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/29971992/a-biomechanical-case-study-on-the-optimal-orthodontic-force-on-the-maxillary-canine-tooth-based-on-finite-element-analysis
#4
Jian-Lei Wu, Yun-Feng Liu, Wei Peng, Hui-Yue Dong, Jian-Xing Zhang
Excessive forces may cause root resorption and insufficient forces would introduce no effect in orthodontics. The objective of this study was to investigate the optimal orthodontic forces on a maxillary canine, using hydrostatic stress and logarithmic strain of the periodontal ligament (PDL) as indicators. Finite element models of a maxillary canine and surrounding tissues were developed. Distal translation/tipping forces, labial translation/tipping forces, and extrusion forces ranging from 0 to 300 g (100 g=0...
July 2018: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/29971991/effect-of-ultraviolet-photofunctionalization-of-dental-titanium-implants-on-osseointegration
#5
Christian Mehl, Matthias Kern, Friederike Neumann, Telse Bähr, Jörg Wiltfang, Volker Gassling
OBJECTIVE: The aim of the current study was to evaluate the effect of ultraviolet (UV) photofunctionalization of dental titanium implants with exposure to the oral cavity on osseointegration in an animal model. METHODS: Forty-eight titanium implants (Camlog® Conelog® 4.3 mmx9.0 mm) were placed epicrestally into the edentulous jaws of three minipigs and implant stability was assessed by measuring the implant stability quotient (ISQ). Prior to implantation half of the implants were photofunctionalized with intense UV-light...
July 2018: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/29971990/mandatory-criteria-for-the-application-of-variability-based-parameters-of-fluid-responsiveness-a-prospective-study-in-different-groups-of-icu-patients
#6
Wolfgang Huber, Uli Mayr, Andreas Umgelter, Michael Franzen, Wolfgang Reindl, Roland M Schmid, Florian Eckel
BACKGROUND AND OBJECTIVE: Stroke volume variation (SVV) has high sensitivity and specificity in predicting fluid responsiveness. However, sinus rhythm (SR) and controlled mechanical ventilation (CV) are mandatory for their application. Several studies suggest a limited applicability of SVV in intensive care unit (ICU) patients. We hypothesized that the applicability of SVV might be different over time and within certain subgroups of ICU patients. Therefore, we analysed the prevalence of SR and CV in ICU patients during the first 24 h of PiCCO-monitoring (primary endpoint) and during the total ICU stay...
July 2018: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/29971989/depolymerized-konjac-glucomannan-preparation-and-application-in-health-care
#7
Min Jiang, Heng Li, Jin-Song Shi, Zheng-Hong Xu
Konjac glucomannan (KGM) is a water-soluble polysaccharide obtained from the roots and tubers of konjac plants. Recently, a degraded product of KGM, depolymerized KGM (DKGM), has attracted attention because of its low viscosity, improved hydrophily, and favorable physiological functions. In this review, we describe the preparation of DKGM and its prebiotic effects. Other health benefits of DKGM, covering antioxidant and immune activity, are also discussed, as well as its safety. DKGM could be a candidate for use as a tool for the treatment of various diseases, including intestinal flora imbalance, and oxidative- and immune-related disorders...
July 2018: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/29971988/advances-in-predicting-the-prognosis-of-hepatocellular-carcinoma-recipients-after-liver-transplantation
#8
Li-Ying Wang, Shu-Sen Zheng
Hepatocellular carcinoma (HCC) is one of the most prevalent malignant tumors worldwide. Liver transplantation (LT) is known as a curative and therapeutic modality. However, the survival rates of recipients after LT are still not good enough because of tumor recurrence. To improve the survival rates of recipients after LT, identifying predictive factors for prognosis after LT and establishing a model assessing prognosis are very important to HCC patients. There has recently been a lot of clinical and basic research on recurrence and prognosis after LT...
July 2018: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/29732752/avian-influenza-viruses-aivs-h9n2-are-in-the-course-of-reassorting-into-novel-aivs
#9
Hui-Ping Chang, Li Peng, Liang Chen, Lu-Fang Jiang, Zhi-Jie Zhang, Cheng-Long Xiong, Gen-Ming Zhao, Yue Chen, Qing-Wu Jiang
In 2013, two episodes of influenza emerged in China and caused worldwide concern. A new H7N9 avian influenza virus (AIV) first appeared in China on February 19, 2013. By August 31, 2013, the virus had spread to ten provinces and two metropolitan cities. Of 134 patients with H7N9 influenza, 45 died. From then on, epidemics emerged sporadically in China and resulted in several victims. On November 30, 2013, a 73-year-old woman presented with an influenza-like illness. She developed multiple organ failure and died 9 d after the onset of disease...
May 2018: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/29732751/neurological-responses-of-embryo-larval-zebrafish-to-short-term-sediment-exposure-to-decabromodiphenylethane
#10
Mei-Qing Jin, Dong Zhang, Ying Zhang, Shan-Shan Zhou, Xian-Ting Lu, Hong-Ting Zhao
Decabromodiphenylethane (DBDPE) has been widely used as an alternative flame retardant due to the restriction or phase-out of traditional polybrominated diphenyl ethers (PBDEs), and is of increasing concern regarding its ubiquity, persistence, and potential adverse effects. In the present study, the toxicological effects of DBDPE were evaluated using zebrafish as an in vivo model. Upon being exposed to DBDPE-polluted sediments for a short term, it was found that the mortality and malformation of zebrafish (including edema, bent notochord, and bent tail) were not affected even at the highest concentration tested (1000...
May 2018: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/29732750/age-related-changes-of-yolk-precursor-formation-in-the-liver-of-laying-hens
#11
Xing-Ting Liu, Xin Lin, Yu-Ling Mi, Wei-Dong Zeng, Cai-Qiao Zhang
A rapid decline in egg production of laying hens begins after 480 d of age. Such a rapid decrease results predominantly from the ovarian aging, accompanied by endocrine changes, decreased yolk synthesis and accumulation, and the reduction in follicles selected into the preovulatory hierarchy. In this study, hens at 90, 150, 280, and 580 d old (D90, D150, D280, and D580, respectively) were compared for yolk precursor formation in the liver to elucidate effects of aging on laying performance. The results showed that liver lipid synthesis increased remarkably in hens from D90 to D150, but decreased sharply at D580 as indicated by the changes in triglyceride (TG) levels...
May 2018: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/29732749/creation-of-a-rabbit-model-for-intrauterine-adhesions-using-electrothermal-injury
#12
Xin-Xin Xu, Lian-Bao Cao, Zhe Wang, Zhen Xu, Bing-Qian Zhang, She-Ling Wu, Sha-Sha Qi, Lei Yan, Zi-Jiang Chen
The pathogenesis and therapeutic treatment of intrauterine adhesions (IUAs) remain unsolved, highlighting the need for stable and effective experimental animal models. In this study, uterine electrocoagulation of twenty-one female New Zealand White rabbits was carried out to establish an IUA model. As rabbits have two completely separate uterine horns, each rabbit had its own internal control: one uterine horn was given an electrothermal injury (Group A, n=21), and the contralateral uterine horn received no treatment and served as the control (Group B, n=21)...
May 2018: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/29732748/surface-characteristics-and-mechanical-behavior-of-retrieved-orthodontic-microimplants
#13
Lu Lu, Hyo-Sang Park
OBJECTIVES: To observe the surface characteristics and mechanical behavior of retrieved microimplants under clinically simulating experimental conditions and to investigate the feasibility of reuse of microimplants. MATERIALS AND METHODS: The microimplants, inserted at different angles, were retrieved from the patients (RMIP) and the artificial bone (RMIA). Surface characteristics, including morphologic changes of tips and thread edges, length reduction, and surface compositional variation, were evaluated using a field emission scanning electron microscope, a stereoscopic microscope, and energy-dispersive X-ray spectroscopy, respectively...
May 2018: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/29732747/antibacterial-and-anti-biofilm-activity-of-the-lipid-extract-from-mantidis-ootheca-on-pseudomonas-aeruginosa
#14
Wen-Dong Wang, Nan-Nan Zhang, Warren Chanda, Min Liu, Syed Riaz Ud Din, Yun-Peng Diao, Lei Liu, Jing Cao, Xiao-Li Wang, Xing-Yun Li, An-Hong Ning, Min Huang, Min-Tao Zhong
The aim of this study is to assess the antibacterial and anti-biofilm properties of the lipid extract from Mantidis ootheca against the gentamycin resistant Pseudomonas aeruginosa. The chemical composition of the lipid extract and its relative proportion were determined using the technique of gas chromatography coupled with mass spectrometry (GC-MS). Antibacterial susceptibility tests were performed using a disc diffusion assay and the minimum inhibition concentration (MIC) was determined by way of the agar dilution method...
May 2018: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/29732746/american-european-and-chinese-practice-guidelines-or-consensuses-of-polycystic-ovary-syndrome-a-comparative-analysis
#15
Fang-Fang Wang, Jie-Xue Pan, Yan Wu, Yu-Hang Zhu, Paul J Hardiman, Fan Qu
Polycystic ovary syndrome (PCOS) is the most common metabolic and endocrine disorder in women. However, there is no agreement concerning how to diagnose and treat PCOS worldwide. Three practice guidelines or consensuses, including consensus from the European Society of Human Reproduction and Embryology (ESHRE)/the American Society for Reproductive Medicine (ASRM) in Rotterdam, diagnosis criteria and consensus in China, and clinical practice guideline from the Endocrine Society (ES) in the United States are widely recognized...
May 2018: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/29732745/combining-fragmented-qrs-and-timi-score-for-predicting-in-hospital-short-term-prognosis-after-acute-myocardial-infarction
#16
Qin-Hui Sheng, Chih Chi Hsu, Jian-Ping Li, Tao Hong, Yong Huo
Acute myocardial infarction (AMI) has a high mortality rate and poor prognosis for patients. The primary causes of death are arrhythmia and heart failure. For patients admitted because of myocardial infarction, various risk evaluations are initiated to foresee possible complications. The thrombolysis in myocardial infarction (TIMI) risk score, which can be used to predict the prognosis and the need for revascularisation, is the most convenient and commonly used system, but is inadequate for AMI patients on admittance...
May 2018: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/29732744/early-diagnosis-of-acute-kidney-injury-in-aged-patients-undergoing-percutaneous-coronary-intervention
#17
Hong-Hua Ye, Gen Shen, Qun Luo, Fang-Fang Zhou, Xiao-Ling Xie, Chun-Yan Wang, Li-Na Han
In aged patients, acute kidney injury (AKI) is a common clinical complication after percutaneous coronary intervention (PCI), highlighting the need for timely and certain diagnosis of this disease. A single centre, nested case-control study was conducted, which assessed the usefulness of urinary liver-type fatty acid-binding protein (uL-FABP), neutrophil gelatinase-associated lipocalin (uNGAL), and kidney injury molecule-1 (uKIM-1) for early detection of AKI. One hundred and thirty-two patients at or over 60 years old undergoing PCI were included...
May 2018: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/29732743/regulation-of-autophagy-by-tea-polyphenols-in-diabetic-cardiomyopathy
#18
Hui Zhou, Yan Chen, Shu-Wei Huang, Peng-Fei Hu, Li-Jiang Tang
OBJECTIVE: To investigate the effect of tea polyphenols on cardiac function in rats with diabetic cardiomyopathy, and the mechanism by which tea polyphenols regulate autophagy in diabetic cardiomyopathy. METHODS: Sixty Sprague-Dawley (SD) rats were randomly divided into six groups: a normal control group (NC), an obesity group (OB), a diabetic cardiomyopathy group (DCM), a tea polyphenol group (TP), an obesity tea polyphenol treatment group (OB-TP), and a diabetic cardiomyopathy tea polyphenol treatment group (DCM-TP)...
May 2018: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/29770647/neuromodulation-for-tinnitus-treatment-an-overview-of-invasive-and-non-invasive-techniques
#19
REVIEW
Nicole Peter, Tobias Kleinjung
Tinnitus is defined as a perception of sound without any external sound source. Chronic tinnitus is a frequent condition that can affect the quality of life. So far, no causal cure for tinnitus has been documented, and most pharmacologic and psychosomatic treatment modalities aim to diminish tinnitus' impact on the quality of life. Neuromodulation, a novel therapeutic modality, which aims at alternating nerve activity through a targeted delivery of a stimulus, has emerged as a potential option in tinnitus treatment...
March 12, 2018: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/30070089/erratum-to-a-cross-sectional-study-of-irritable-bowel-syndrome-in-nurses-in-china-prevalence-and-associated-psychological-and-lifestyle-factors
#20
Liang Liu, Qi-Fan Xiao, Yan-Li Zhang, Shu-Kun Yao
The original version of this article unfortunately contained a mistake. In p.590, the address of Yan-li ZHANG, one of the corresponding authors, is incorrect. The correct address should be: 1Department of Gastroenterology, China-Japan Friendship Hospital, Beijing 100029, China.
2018: Journal of Zhejiang University. Science. B
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