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Annals of General Psychiatry

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https://www.readbyqxmd.com/read/29299043/the-efficacy-acceptability-and-safety-of-five-atypical-antipsychotics-in-patients-with-first-episode-drug-na%C3%A3-ve-schizophrenia-a-randomized-comparative-trial
#1
Congjie Wang, Wenjie Shi, Chengbing Huang, Jiannan Zhu, Wenzhong Huang, Gang Chen
Background: Differences in effectiveness and tolerability between different atypical antipsychotics may affect schizophrenic patients' treatment adherence or prognosis. However, which kind of antipsychotic was more effective and safe in the treatment of schizophrenia is still being debated. This study attempted to understand whether there are any differences in efficacy, acceptability, and safety between the five atypical antipsychotics in patients with first-episode schizophrenia. Methods: Two hundred cases of inpatients with first-episode drug-naïve schizophrenia were randomly assigned to 6-8 weeks of treatment with either of aripiprazole, risperidone, quetiapine, olanzapine, or ziprasidone from October 2012 to November 2014...
2017: Annals of General Psychiatry
https://www.readbyqxmd.com/read/29259655/continuation-with-clozapine-after-eosinophilia-a-case-report
#2
Yen-Cheng Ho, Huang-Li Lin
Background: Clozapine-induced eosinophilia had been reported in several studies about blood dyscrasias in clozapine-treated patient. The largest study with 2404 patients in Italy found the incidence of 2.2% by criteria of more than 0.4 × 109/l. Associated cases of pancreatitis, hepatitis, colitis, nephritis, and myocarditis were reported. Interestingly, incidence of myocarditis is high in Australia, but low in the rest of the world. In the following, we will present a case of clozapine-induced eosinophilia which spontaneous resolution was noted under continuation of clozapine...
2017: Annals of General Psychiatry
https://www.readbyqxmd.com/read/29234453/an-association-study-of-taq1a-ankk1-and-c957t-and-%C3%A2-141c-drd2-polymorphisms-in-adults-with-internet-gaming-disorder-a-pilot-study
#3
Soo-Hyun Paik, Mi Ran Choi, Su Min Kwak, Sol Hee Bang, Ji-Won Chun, Jin-Young Kim, Jihye Choi, Hyun Cho, Jo-Eun Jeong, Dai-Jin Kim
Background: Though Internet gaming disorder (IGD) is considered to share similar genetic vulnerability with substance addictions, little has been explored about the role of the genetic variants on IGD. This pilot study was designed to investigate the association of the Taq1A polymorphism of the ankyrin repeat and kinase domain containing 1 (ANKK1) gene and C957T and - 141C of the dopamine D2 receptor (DRD2) with IGD and their role on the personality and temperament traits in IGD among adult population...
2017: Annals of General Psychiatry
https://www.readbyqxmd.com/read/29213296/comparison-of-the-characteristics-of-suicide-attempters-with-major-depressive-disorder-and-those-with-no-psychiatric-diagnosis-in-emergency-departments-of-general-hospitals-in-china
#4
Shengnan Wei, Haiyan Li, Jinglin Hou, Wei Chen, Xu Chen, Xiaoxia Qin
Background: Major depressive disorder (MDD) is a known major risk factor for suicide due to the high suicide mortality. However, studies comparing the characteristics of suicide attempters with major depressive disorder and those with no psychiatric diagnosis in China are very limited. This study examined and compared the sociodemographic and psychological characteristics of suicide attempters with MDD and those with no psychiatric diagnosis in emergency departments of general hospitals to better understand the risk factors for suicide attempts in China...
2017: Annals of General Psychiatry
https://www.readbyqxmd.com/read/29209406/serum-prolactin-levels-and-sexual-dysfunction-in-patients-with-schizophrenia-treated-with-antipsychotics-comparison-between-aripiprazole-and-other-atypical-antipsychotics
#5
Eiji Kirino
Objectives: Antipsychotics, even atypical ones, can induce hyperprolactinemia. Aripiprazole (APZ), a dopamine D2 partial agonist, has a unique pharmacological profile and few side effects. We investigated the incidence of hyperprolactinemia in patients with schizophrenia treated with APZ and other antipsychotics. Methods: Serum prolactin levels were measured by ELISA (enzyme-linked immunosorbent assay). A questionnaire survey was used to evaluate subjective sexual dysfunction...
2017: Annals of General Psychiatry
https://www.readbyqxmd.com/read/29201132/a-multilevel-longitudinal-study-of-obsessive-compulsive-symptoms-in-adolescence-male-gender-and-emotional-stability-as-protective-factors
#6
Vasilis Stavropoulos, Kathleen A Moore, Helen Lazaratou, Dimitris Dikaios, Rapson Gomez
The severity of obsessive compulsive symptoms (OCS) is suggested to be normally distributed in the general population, and they appear to have an impact on a range of aspects of adolescent development. Importantly, there are individual differences regarding susceptibility to OCS. In the present repeated measures study, OCS were studied in relation to gender and emotional stability (as a personality trait) using a normative sample of 515 adolescents at ages 16 and 18 years. OCS were assessed with the relevant subscale of the SCL-90-R and emotional stability with the Five Factor Questionnaire...
2017: Annals of General Psychiatry
https://www.readbyqxmd.com/read/29176997/association-between-an-angiotensin-converting-enzyme-gene-polymorphism-and-alzheimer-s-disease-in-a-tunisian-population
#7
Najiba Fekih-Mrissa, Ines Bedoui, Aycha Sayeh, Hajer Derbali, Meriem Mrad, Ridha Mrissa, Brahim Nsiri
Background: The angiotensin-converting enzyme gene (ACE) insertion/deletion (I/D or indel) polymorphism has long been linked to Alzheimer's disease (AD), but the interpretation of established data remains controversial. The aim of this study was to determine whether the angiotensin-converting enzyme is associated with the risk of Alzheimer's disease in Tunisian patients. Methods: We analyzed the genotype and allele frequency distribution of the ACE I/D gene polymorphism in 60 Tunisian AD patients and 120 healthy controls...
2017: Annals of General Psychiatry
https://www.readbyqxmd.com/read/29176996/mental-neurologic-and-substance-use-mns-disorders-among-street-homeless-people-in-ethiopia
#8
Getinet Ayano, Dawit Assefa, Kibrom Haile, Asrat Chaka, Haddish Solomon, Petros Hagos, Zegeye Yohannis, Kelemua Haile, Lulu Bekana, Melkamu Agidew, Seife Demise, Belachew Tsegaye, Melat Solomon
Background: About 25-60% of the homeless population is reported to have some form of mental disorder. To our knowledge, there are no studies aimed at the screening, diagnosis, treatment, care, rehabilitation, and support of homeless people with mental, neurologic, and substance use (MNS) disorders in general in Ethiopia. This is the first study of its kind in Africa which was aimed at screening, diagnosis, care, treatment, rehabilitation, and support of homeless individuals with possible MNS disorder...
2017: Annals of General Psychiatry
https://www.readbyqxmd.com/read/29176995/depression-is-related-to-dietary-diversity-score-in-women-a-cross-sectional-study-from-a-developing-country
#9
REVIEW
Mina Poorrezaeian, Fereydoun Siassi, Alireza Milajerdi, Mostafa Qorbani, Javad Karimi, Reza Sohrabi-Kabi, Neda Pak, Gity Sotoudeh
Background: Substantial evidence provides support for the role of diet in the prevention and control of mental disorders. However, since there is no study regarding the relationship between dietary diversity and stress or depression, we aimed to determine the relationship between the dietary diversity score (DDS) and stress and depression in women. Methods: This descriptive-analytical cross-sectional study was performed on 360 women aged 20-49 years attending health centers in the south of Tehran...
2017: Annals of General Psychiatry
https://www.readbyqxmd.com/read/29093741/insulin-like-growth-factor-1-a-possible-marker-for-emotional-and-cognitive-disturbances-and-treatment-effectiveness-in-major-depressive-disorder
#10
REVIEW
Oleg A Levada, Alexandra S Troyan
Depression and cognitive dysfunction share a common neuropathological platform. Abnormal neural plasticity in the frontolimbic circuits has been linked to changes in the expression of neurotrophic factors, including IGF-1. These changes may result in clinical abnormalities observed over the course of major depressive disorder (MDD), including cognitive dysfunction. The present review aimed to summarize evidence regarding abnormalities of peripheral IGF-1 in MDD patients and assess a marker and predictive role of the neurotrophin for emotional and cognitive disturbances, and treatment effectiveness...
2017: Annals of General Psychiatry
https://www.readbyqxmd.com/read/29075310/relationship-between-the-experience-of-being-a-bully-victim-and-mental-health-in-preadolescence-and-adolescence-a-cross-sectional-study
#11
Sachiko Kozasa, Arata Oiji, Akio Kiyota, Tetsuji Sawa, Soo-Yung Kim
BACKGROUND: Several studies have proven that the experiences of being bullied or bullying others are associated with poor mental health among adolescent youths. Our study aims to investigate the relationship between the experience of the bully/victim and mental health among preadolescents and adolescents. METHODS: Subjects were the Japanese fifth and sixth grade elementary school students (preadolescents: mean age = 11.3 years; n = 338) and junior high school students (adolescents: mean age = 13...
2017: Annals of General Psychiatry
https://www.readbyqxmd.com/read/29075309/weight-changes-before-and-after-lurasidone-treatment-a-real-world-analysis-using-electronic-health-records
#12
Jonathan M Meyer, Daisy S Ng-Mak, Chien-Chia Chuang, Krithika Rajagopalan, Antony Loebel
BACKGROUND: Severe and persistent mental illnesses, such as schizophrenia and bipolar disorder, are associated with increased risk of obesity compared to the general population. While the association of lurasidone and lower risk of weight gain has been established in short and longer-term clinical trial settings, information about lurasidone's association with weight gain in usual clinical care is limited. This analysis of usual clinical care evaluated weight changes associated with lurasidone treatment in patients with schizophrenia or bipolar disorder...
2017: Annals of General Psychiatry
https://www.readbyqxmd.com/read/29075308/psychological-and-somatic-distress-in-chinese-outpatients-at-general-hospitals-a-cross-sectional-study
#13
Nana Xiong, Jing Wei, Kurt Fritzsche, Rainer Leonhart, Xia Hong, Tao Li, Jing Jiang, Liming Zhu, Guoqing Tian, Xudong Zhao, Lan Zhang, Rainer Schaefert
BACKGROUND: Our study aimed (1) to describe the proportion of psychological distress among Chinese outpatients at general hospitals, (2) to compare cognitive and behavioral characteristics of patients with different distress patterns, and (3) to investigate the discriminant function of the analyzed variables in indicating the affinity towards the different distress patterns. METHODS: This multicenter cross-sectional study was conducted at ten outpatient departments at Chinese general hospitals...
2017: Annals of General Psychiatry
https://www.readbyqxmd.com/read/29021815/analysis-of-eeg-entropy-during-visual-evocation-of-emotion-in-schizophrenia
#14
Wen-Lin Chu, Min-Wei Huang, Bo-Lin Jian, Kuo-Sheng Cheng
BACKGROUND: In this study, the international affective picture system was used to evoke emotion, and then the corresponding signals were collected. The features from different points of brainwaves, frequency, and entropy were used to identify normal, moderately, and markedly ill schizophrenic patients. METHODS: The signals were collected and preprocessed. Then, the signals were separated according to three types of emotions and five frequency bands. Finally, the features were calculated using three different methods of entropy...
2017: Annals of General Psychiatry
https://www.readbyqxmd.com/read/28936227/hospital-nurses-attitudes-negative-perceptions-and-negative-acts-regarding-workplace-bullying
#15
Shu-Ching Ma, Hsiu-Hung Wang, Tsair-Wei Chien
BACKGROUND: Workplace bullying is a prevalent problem in today's work places that has adverse effects on both bullying victims and organizations. To investigate the predictors of workplace bullying is an important task to prevent bullying victims of nurses in hospitals. OBJECTIVE: This study aims to explore the relationships among nurses' attitudes, negative perceptions, and negative acts regarding workplace bullying under the framework of the theory of planned behavior (TPB)...
2017: Annals of General Psychiatry
https://www.readbyqxmd.com/read/28878812/an-arabic-translation-reliability-and-validation-of-patient-health-questionnaire-in-a-saudi-sample
#16
Ahmad N AlHadi, Deemah A AlAteeq, Eman Al-Sharif, Hamdah M Bawazeer, Hasan Alanazi, Abdulaziz T AlShomrani, Raafat M Shuqdar, Reem AlOwaybil
BACKGROUND: Psychological disorders including depression and anxiety are not rare in primary care clinics. The Patient Health Questionnaire (PHQ) is a clinical diagnostic tool that is widely utilized by primary health care physicians worldwide because it provides a practical in-clinic tool to screen for psychological disorders. This study evaluated the validity of the Arabic version of the PHQ in all six modules including depression, anxiety, somatic, panic, eating, and alcohol abuse disorders...
2017: Annals of General Psychiatry
https://www.readbyqxmd.com/read/28808477/effect-of-lamotrigine-in-the-treatment-of-bipolar-depression-with-psychotic-features-a-case-report
#17
Tomoko Kajiya, Hiroko Sugawara, Yusuke Kajio, Satoru Morieda, Hibiki Tanaka, Tadashi Jono, Noboru Fujise, Mamoru Hashimoto
BACKGROUND: Major depressive episodes with psychotic features are more common in bipolar disorder than in major depressive disorder; however, there is little information on the optimal treatment for bipolar depression with psychotic features. CASE PRESENTATION: The patient was a 69-year-old man. At the age of 66, he was admitted to the hospital for the treatment of bipolar depression with psychotic features. He was treated with a combination therapy of antipsychotics and antidepressants during long-term hospitalization...
2017: Annals of General Psychiatry
https://www.readbyqxmd.com/read/28717382/neurological-soft-signs-in-tunisian-patients-with-first-episode-psychosis-and-relation-with-cannabis-use
#18
Ahmed Mhalla, Bochra Ben Mohamed, Christoph U Correll, Badii Amamou, Anouar Mechri, Lotfi Gaha
BACKGROUND: Neurological soft signs (NSS) are minor non-localizing neurological abnormalities that are conceptualized as neurodevelopmental markers that mediate the biological risk for psychosis. We aimed to explore the relationship between NSS and cannabis use, an environmental risk factor of psychosis. METHODS: This was a cross-sectional study in consecutively admitted patients hospitalized for first-episode psychosis. NSS were assessed by the NSS scale (23 items exploring motor coordination, motor integrative function, sensory integration, involuntary movements or posture, quality of lateralization)...
2017: Annals of General Psychiatry
https://www.readbyqxmd.com/read/28702070/leveling-and-abuse-among-patients-with-bipolar-disorder-at-psychiatric-outpatient-departments-in-ethiopia
#19
Habte Belete
INTRODUCTION: The World Health Organization (WHO) clearly states the importance of psychological well-being in the definition of health as "a state of complete physical, mental and social well-being and not merely the absence of disease or infirmity". However, in the community, the lives of people with bipolar disorders are often harsh and abusive. Till now, the rate and related information concerning verbal or physical abuse among patients with bipolar disorder at psychiatric outpatient clinics have not been well addressed in Ethiopian settings...
2017: Annals of General Psychiatry
https://www.readbyqxmd.com/read/28694841/islam-mental-health-and-law-a-general-overview
#20
REVIEW
Georgios A Tzeferakos, Athanasios I Douzenis
Islam is the dominant religion in about 56 countries around the globe, and has more than 1.2 billion followers. Islam represents a holistic way of life, and according to a large proportion of its followers, the Islamic law or Shari'ah should prevail over secular law and should be implemented as state law. The etymological root of the word Shari'ah can be traced back to the harsh life in the desert and it means "pathway to be followed" or "path to the water hole," since the water was the basic element and preserver of life...
2017: Annals of General Psychiatry
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