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Annals of General Psychiatry

Shengnan Wei, Miao Chang, Ran Zhang, Xiaowei Jiang, Fei Wang, Yanqing Tang
Background: Major depressive disorder (MDD) is a known major risk factor for suicide and is one of the most common mental disorders. Meanwhile, gender differences in suicidal behavior have long been recognized including the finding that women have higher rates of suicidal ideation and/or suicidal behavior than men. The mechanism underlying suicide ideation in female patients with MDD remains poorly understood. The aim of the present study was to examine possible suicidal behavior-related neural circuitry in female MDD...
2018: Annals of General Psychiatry
Athanasios Apostolopoulos, Ioannis Michopoulos, Ioannis Zachos, Emmanouil Rizos, Georgios Tzeferakos, Vasiliki Manthou, Charalambos Papageorgiou, Athanasios Douzenis
Background: Personality disorders (PDs) have been associated with both violent crimes and homicides in many studies. The proportion of PDs among prisoners reaches up to 80%. For male prisoners, the most common PD in the literature is antisocial PD. The aim of this study was to investigate the association between PDs and violent crimes/homicides of male prisoners in Greece. Methods: A sample of 308 subjects was randomly selected from a population of 1300 male prisoners incarcerated in two Greek prisons, one urban and one rural...
2018: Annals of General Psychiatry
Melak Menberu, Tesfa Mekonen, Telake Azale, Getinet Ayano, Solomon Yimer, Asmamaw Getnet, Amsalu Belete, Sitotaw Kerie, Wubalem Fekadu
Background: Depression is one of the most disabling and chronic mental illnesses. Despite its high burden, many people suffering from depression did not perceive that they had a treatable illness and consequently most of them did not seek professional help. The aim of this study was to assess the level of professional help-seeking behavior and associated factors among individuals with depression. Methods and materials: The community-based cross-sectional study was conducted among residents of Dessie, Northeast Ethiopia...
2018: Annals of General Psychiatry
Elmars Rancans, Marcis Trapencieris, Rolands Ivanovs, Jelena Vrublevska
Background: Depression is highly underdiagnosed in primary care settings in Latvia. Screening for depression in primary care is potentially an efficient way to find undetected case s and improve diagnostics. We aimed to validate both a nine-item and two-item Patient Health Questionnaire (PHQ-9 and PHQ-2) in the Latvian and Russian languages in primary care settings using a representative sample in Latvia. Materials and methods: The study was carried out within the framework of the National Research Program BIOMEDICINE to assess the prevalence of mental disorders at 24 primary care facilities...
2018: Annals of General Psychiatry
Yang-Whan Jeon, Sang-Ick Han, E Jin Park
Background: The associations between depression and immunity were investigated by measuring the scores of Hamilton Rating Scale for Depression (HRSD) and peripheral lymphocyte parameters in patients with major depressive disorder (MDD). Methods: Forty-nine patients with MDD were recruited and their clinical symptoms are evaluated with 17-item HRSD which was factorized using the confirmatory factor analysis (i.e., depression factor, insomnia factor, and anxiety factor)...
2018: Annals of General Psychiatry
Kingi Mochache, Muthoni Mathai, Onesmus Gachuno, Ann Vander Stoep, Manasi Kumar
Background: Preterm birth occurs among 9.6% of births worldwide and is the leading cause of long-term neurodevelopmental disabilities among children and also responsible for 28% of neonatal deaths. No single etiological factor is responsible for preterm birth, but various risk factors have been identified. Prior studies have reported that compromised maternal mental health occurring during pregnancy may lead to various adverse obstetric outcomes. Objective: To determine whether antenatal depression is significantly associated with preterm delivery in a low resource hospital sample from suburbs of Nairobi...
2018: Annals of General Psychiatry
Jay Moss, Dippy Nauranga, Doyoung Kim, Michael Rosen, Karen Wang, Krista Lanctot
Background: Hospital-based physicians must routinely decide whether patients receiving care in the emergency room require admission to an acute care bed. We endeavoured to understand clinician-related factors that influence the decision to admit. Methods: We retrospectively examined data collected between August 1, 2013 and July 31, 2015 for patients triaged as mental health assessments in the emergency department of a university teaching hospital. We identified 1530 unique cases who had been reviewed by the staff psychiatrist for a decision on whether to admit to an acute care bed...
2018: Annals of General Psychiatry
Douglas Gaitho, Manasi Kumar, Dalton Wamalwa, Grace Nduku Wambua, Ruth Nduati
Background: Globally adolescents continue to have an upward trend in HIV incidence and AIDS-related mortality. The interplay between the rapid physical growth, sexual maturation, and enormous albeit slow-evolving cognitive and psychological changes in adolescence may partly explain this trend. Our main purpose was to highlight key psychosocial characteristics of HIV-infected adolescents and explore if these characteristics are associated with depression symptoms. Methods: From August to December 2016 after obtaining informed consent, adolescents living with HIV at Kenyatta National Hospital were interviewed using the Home environment, Education and Employment, Activity, Sexuality, Suicide and depression traits (HEADSS) tool combined with the Patient Health Questionnaire (PHQ-9) to elucidate which key symptoms of depression and link with psychosocial characteristics mapped on HEADSS...
2018: Annals of General Psychiatry
Concetta De Pasquale, Carmela Dinaro, Federica Sciacca
The purpose of this study was twofold: (a) to investigate the prevalence of Internet gaming disorder (IGD) among Italian university students and (b) to explore the associations between the former and dissociative phenomena. The sample included 221 college students, 93 males and 128 females, aged between 18 and 25 ( M  = 21.56; SD = 1.42). They were asked to state their favourite games choice and were administered a demographic questionnaire, the APA symptom checklist based on the diagnostic criteria of IGD in the DSM-5, the Internet Gaming Disorder Scale Short Form (IGD9-SF) and the Italian version of dissociative experience scale for adolescents and young adults...
2018: Annals of General Psychiatry
Asrat Chaka, Tadesse Awoke, Zegeye Yohannis, Getinet Ayano, Minale Tareke, Andargie Abate, Mulugeta Nega
Background: Depression is the most frequently and highly occurring mental disorders in epilepsy patients. When depression is comorbid with epilepsy, it leads to low employment and poor quality of life. Thus, the aim of this study was to assess the prevalence and associated factors of depression among people living with epilepsy in Central Ethiopia. Methods: Institution-based cross-sectional study was conducted from April to May 2015 at Amanuel Mental Specialized and TikurAnbesa Hospitals, Addis Ababa, Ethiopia...
2018: Annals of General Psychiatry
Andargie Abate, Minale Tareke, Mulat Tirfie, Ayele Semachew, Desalegne Amare, Emiru Ayalew
Introduction: Khat is a well-known natural stimulant and is widely used in Ethiopia, particularly in Bahir Dar city. Khat chewing is linked with risky sexual behaviors. Objective: The study was aimed to determine the prevalence of chewing khat and its relation with risky sexual behaviors among residents of Bahir Dar City administration, Northwest Ethiopia. Methods: A community based cross-sectional study was conducted from January to February, 2016...
2018: Annals of General Psychiatry
Angela J Pereira-Morales, Ana Adan, Sandra Lopez-Leon, Diego A Forero
Background: The study of health-related quality of life (HRQOL) is an important topic in mental health around the globe. However, there is the need for more evidence about the cumulative influence of psychological variables on HRQOL. The main aim of the study was to evaluate how specific personality traits might explain scores in HRQOL and to explore how this relationship might be mediated by coping styles and psychological distress. Methods: Young Colombian subjects ( N  = 274) were included (mean age: 21...
2018: Annals of General Psychiatry
Eun Hyun Seo, Hae Jung Yang, Sang Hoon Kim, Jung Hyun Park, Hyung-Jun Yoon
Background: Neurosyphilis remains a diagnostic challenge in current psychiatric practice because of its pleomorphic psychiatric manifestations. Although neurosyphilis can present with a wide range of psychiatric symptoms, psychotic mania as its solitary manifestation is an unusual phenomenon. Case presentation: A 46-year-old man, with no history of any psychiatric disorder, exhibited abruptly developed symptoms of psychotic mania. He was admitted to a psychiatric ward for further evaluation and treatment...
2018: Annals of General Psychiatry
Bereket Duko, Getinet Ayano
Background: People with severe mental disorders are associated with increased risk of suicide and suicide attempts compared to the general population. In low and middle-income countries, research concerning suicide attempts and completed suicide among people living with severe mental disorder is limited. The objective of this study was to assess suicide and attempts in people with severe mental disorder at Amanuel Mental Specialized Hospital, Addis Ababa, Ethiopia. Methods: Institution-based cross-sectional study was conducted in August-September 2016...
2018: Annals of General Psychiatry
Hiba Alblooshi, Gary Hulse, Wael Osman, Ahmed El Kashef, Mansour Shawky, Hamad Al Ghaferi, Habiba Al Safar, Guan K Tay
Background: Dopaminergic and opioid systems are involved in mediating drug reward and reinforcement of various types of substances including psychoactive compounds. Genes of both systems have been candidate for investigation for associations with substance use disorder (SUD) in various populations. This study is the first study to determine the allele frequency and the genetic association of the DRD2 rs1076560 SNP and OPRM1 rs1799971 SNP variants in clinically diagnosed patients with SUD from the United Arab Emirates (UAE)...
2018: Annals of General Psychiatry
Imad El Majzoub, Christopher El Khuri, Karim Hajjar, Ralphe Bou Chebl, Farid Talih, Maha Makki, Aurelie Mailhac, Gilbert Abou Dagher
Background: Emergency Department (ED) visits for suicide attempts have been described worldwide; however, the populations studied were predominantly Western European, North American, or East Asian. This study aims to describe the epidemiology of ED patients presenting post-suicide attempt to an academic medical center in Lebanon and to report on factors that affect ED disposition. Methods: A retrospective cohort study was conducted between 2009 and 2015. Patients of any age group were included if they had presented to the ED after a suicide attempt...
2018: Annals of General Psychiatry
Rajnish Mago, Andrea Fagiolini, Emmanuelle Weiller, Catherine Weiss
Background: Despite the availability of effective antidepressants, about half of patients with major depressive disorder (MDD) display an inadequate response to their initial treatment. A large patient survey recently reported that 29.8% of MDD patients experiencing an inadequate treatment response felt frustrated about their medication and 19.2% were frustrated with their healthcare provider. This survey and chart audit evaluated healthcare professionals' (HCP) views on the emotional impact of having an inadequate response to antidepressant medication...
2018: Annals of General Psychiatry
Anish Shah, Joanne Northcutt
Background: Despite the current treatments available for panic disorder (PD), as many as one-third of patients have persistent and treatment-resistant panic attacks. Vortioxetine is an approved medicine for major depressive disorder and has been shown to have anxiolytic properties. The purpose of this study was to evaluate its efficacy and safety in an adult population with a diagnosis of PD. Methods: The study design was open label with flexible dose strategies (5, 10, or 20 mg) with a treatment period of 10 weeks...
2018: Annals of General Psychiatry
Reindolf Anokye, Enoch Acheampong, Amy Budu-Ainooson, Edmund Isaac Obeng, Adjei Gyimah Akwasi
Introduction: Postpartum depression is a mood disorder that affects approximately 10-15% of adult mothers yearly. This study sought to determine the prevalence of postpartum depression and interventions utilized for its management in a Health facility in Ghana. Methods: A descriptive cross-sectional study design using a quantitative approach was used for the study. The study population included mothers and healthcare workers. Simple random sampling technique was used to select 257 mothers, while a convenience sampling technique was used to select 56 health workers for the study...
2018: Annals of General Psychiatry
Claudia Carmassi, Camilla Gesi, Martina Corsi, Ivan M Cremone, Carlo A Bertelloni, Enrico Massimetti, Maria Cristina Olivieri, Ciro Conversano, Massimo Santini, Liliana Dell'Osso
Background: Emergency services personnel face frequent exposure to potentially traumatic events, with the potential for chronic symptomatic distress. The DSM-5 recently recognized a particular risk for post-traumatic stress disorder (PTSD) among first responders (criterion A4) but data are still scarce on prevalence rates and correlates. Objective: The aim of the present study was to explore the possible role of age, gender, and education training in a sample of emergency personnel diagnosed with DSM-5 PTSD...
2018: Annals of General Psychiatry
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