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Annals of General Psychiatry

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https://www.readbyqxmd.com/read/29760763/an-open-label-flexible-dose-adaptive-study-evaluating-the-efficacy-of-vortioxetine-in-subjects-with-panic-disorder
#1
Anish Shah, Joanne Northcutt
Background: Despite the current treatments available for panic disorder (PD), as many as one-third of patients have persistent and treatment-resistant panic attacks. Vortioxetine is an approved medicine for major depressive disorder and has been shown to have anxiolytic properties. The purpose of this study was to evaluate its efficacy and safety in an adult population with a diagnosis of PD. Methods: The study design was open label with flexible dose strategies (5, 10, or 20 mg) with a treatment period of 10 weeks...
2018: Annals of General Psychiatry
https://www.readbyqxmd.com/read/29760762/prevalence-of-postpartum-depression-and-interventions-utilized-for-its-management
#2
Reindolf Anokye, Enoch Acheampong, Amy Budu-Ainooson, Edmund Isaac Obeng, Adjei Gyimah Akwasi
Introduction: Postpartum depression is a mood disorder that affects approximately 10-15% of adult mothers yearly. This study sought to determine the prevalence of postpartum depression and interventions utilized for its management in a Health facility in Ghana. Methods: A descriptive cross-sectional study design using a quantitative approach was used for the study. The study population included mothers and healthcare workers. Simple random sampling technique was used to select 257 mothers, while a convenience sampling technique was used to select 56 health workers for the study...
2018: Annals of General Psychiatry
https://www.readbyqxmd.com/read/29755579/exploring-ptsd-in-emergency-operators-of-a-major-university-hospital-in-italy-a-preliminary-report-on-the-role-of-gender-age-and-education
#3
Claudia Carmassi, Camilla Gesi, Martina Corsi, Ivan M Cremone, Carlo A Bertelloni, Enrico Massimetti, Maria Cristina Olivieri, Ciro Conversano, Massimo Santini, Liliana Dell'Osso
Background: Emergency services personnel face frequent exposure to potentially traumatic events, with the potential for chronic symptomatic distress. The DSM-5 recently recognized a particular risk for post-traumatic stress disorder (PTSD) among first responders (criterion A4) but data are still scarce on prevalence rates and correlates. Objective: The aim of the present study was to explore the possible role of age, gender, and education training in a sample of emergency personnel diagnosed with DSM-5 PTSD...
2018: Annals of General Psychiatry
https://www.readbyqxmd.com/read/29755578/a-systematic-review-and-meta-analysis-of-gender-difference-in-epidemiology-of-hiv-hepatitis-b-and-hepatitis-c-infections-in-people-with-severe-mental-illness
#4
REVIEW
Getinet Ayano, Mikiyas Tulu, Kibrom Haile, Dawit Assefa, Yodit Habtamu, Gebresilassie Araya, Zegeye Yohannis
Background: People with severe mental disorders (SMDs) are associated with increased risk of infectious disease including human immunodeficiency virus infection (HIV) and hepatitis viruses, such as hepatitis B virus (HBV), hepatitis C virus (HCV), and other types of hepatitis viruses because of high-risk behaviors compared to the general population. The prevalence of HIV in people with SMDs is higher in females than in males. Unlike HIV, the prevalence of HBV and HCV is higher in males than in females...
2018: Annals of General Psychiatry
https://www.readbyqxmd.com/read/29755577/the-association-between-parental-depression-and-adolescent-s-internet-addiction-in-south-korea
#5
Dong-Woo Choi, Sung-Youn Chun, Sang Ah Lee, Kyu-Tae Han, Eun-Cheol Park
Background: A number of risk factors for Internet addiction among adolescents have been identified to be associated with their behavior, familial, and parental factors. However, few studies have focused on the relationship between parental mental health and Internet addiction among adolescents. Therefore, we investigated the association between parental mental health and children's Internet addiction by controlling for several risk factors. Methods: This study used panel data collected by the Korea Welfare Panel Study in 2012 and 2015...
2018: Annals of General Psychiatry
https://www.readbyqxmd.com/read/29692860/the-long-term-outcome-of-patients-with-heroin-use-disorder-dual-disorder-chronic-psychosis-after-admission-to-enhanced-methadone-maintenance
#6
Angelo G I Maremmani, Alessandro Pallucchini, Luca Rovai, Silvia Bacciardi, Vincenza Spera, Marco Maiello, Giulio Perugi, Icro Maremmani
Background: Over-standard methadone doses are generally needed in the treatment of heroin use disorder (HUD) patients that display concomitant high-severity psychopathological symptomatology. A flexible dosing regimen may lead to higher retention rates in dual disorder (DD), as we demonstrated in bipolar 1 HUD patients, leading to outcomes that are as satisfactory as those of HUD patients without high-severity psychopathological symptomatology. Objective: This study aimed to compare the long-term outcomes of treatment-resistant chronic psychosis HUD patients (PSY-HUD) with those of peers without dual disorder (HUD)...
2018: Annals of General Psychiatry
https://www.readbyqxmd.com/read/29563960/compassion-fatigue-and-substance-use-among-nurses
#7
Reem Jarrad, Sawsan Hammad, Tagreed Shawashi, Naser Mahmoud
Aim: This study aimed to detect if there were differences in compassion fatigue (CF) among nurses based on substance use and demographic variables of gender, marital status, type of health institution and income. Background: Compassion fatigue is considered an outcome of poorly handled stressful situations in which nurses may respond with self-harming behaviours like substance use. Evidence in this area is critically lacking. Methods: This study used a descriptive design to survey differences in CF of 282 nurses...
2018: Annals of General Psychiatry
https://www.readbyqxmd.com/read/29542736/correction-to-suicide-ideation-and-attempts-among-people-with-epilepsy-in-addis-ababa-ethiopia
#8
Kelelemua Haile, Tadesse Awoke, Getinet Ayano, Minale Tareke, Andargie Abate, Mulugeta Nega
[This corrects the article DOI: 10.1186/s12991-018-0174-6.].
2018: Annals of General Psychiatry
https://www.readbyqxmd.com/read/29507598/undetected-psychiatric-morbidity-among-hiv-aids-patients-attending-comprehensive-care-clinic-ccc-in-nairobi-kenya-towards-an-integrated-mental-health-care
#9
Pauline W Ng'ang'a, Muthoni Mathai, Anne Obondo, Teresia Mutavi, Manasi Kumar
Background: Psychiatric morbidity is commonly associated with HIV disease and may have adverse effects. This aspect may be overlooked at comprehensive HIV care centers in Low and Middle-Income Countries. Objectives: The aim of this study was to determine the prevalence of undetected psychiatric morbidity among HIV/AIDS adult patients attending Comprehensive Care Centre in a semi-urban clinic, in Nairobi, Kenya. Design: Descriptive cross-sectional study of adult HIV patients not receiving any psychiatric treatment was conducted...
2018: Annals of General Psychiatry
https://www.readbyqxmd.com/read/29456588/a-survey-of-caregiver-burden-in-those-providing-informal-care-for-patients-with-schizophrenia-or-bipolar-disorder-with-agitation-results-from-a-european-study
#10
Sophee Blanthorn-Hazell, Alfredo Gracia, Jenna Roberts, Anca Boldeanu, Davneet Judge
Background: Agitation is a common feature of bipolar disorder and schizophrenia. Previous research indicates that specific symptoms impact caregiver burden in these conditions, but the impact of agitation on caregiver experience is poorly understood. The aim of this study was to characterise caregiver burden in providers of informal care for patients with bipolar disorder and schizophrenia who experience agitation. Methods: In total, 297 matched patient and caregiver surveys were collected across the UK, Germany and Spain between October 2016 and January 2017...
2018: Annals of General Psychiatry
https://www.readbyqxmd.com/read/29449869/off-label-prescription-of-psychiatric-drugs-by-non-psychiatrist-physicians-in-three-general-hospitals-in-germany
#11
Caroline Lücke, Jürgen M Gschossmann, Teja W Grömer, Sebastian Moeller, Charlotte E Schneider, Aikaterini Zikidi, Alexandra Philipsen, Helge H O Müller
Background: Off-label prescribing of psychoactive drugs is a common practice in psychiatry. Here, we sought to investigate the frequency of off-label prescribing in a population of hospitalized patients with a somatic illness who were also suffering from a psychiatric pathology. Methods: Using a prospective, observational design, we collected data from 982 hospitalized patients with a somatic illness for whom a psychiatric consultation was requested because of the presence of additional psychiatric symptoms...
2018: Annals of General Psychiatry
https://www.readbyqxmd.com/read/29443329/correction-to-psychological-and-somatic-distress-in-chinese-outpatients-at-general-hospitals-a-cross-sectional-study
#12
Nana Xiong, Jing Wei, Kurt Fritzsche, Rainer Leonhart, Xia Hong, Tao Li, Jing Jiang, Liming Zhu, Guoqing Tian, Xudong Zhao, Lan Zhang, Rainer Schaefert
[This corrects the article DOI: 10.1186/s12991-017-0158-y.].
2018: Annals of General Psychiatry
https://www.readbyqxmd.com/read/29422940/strength-based-assessment-for-future-violence-risk-a-retrospective-validation-study-of-the-structured-assessment-of-protective-factors-for-violence-risk-saprof-japanese-version-in-forensic-psychiatric-inpatients
#13
Hiroko Kashiwagi, Akiko Kikuchi, Mayuko Koyama, Daisuke Saito, Naotsugu Hirabayashi
Background: The Structured Assessment of PROtective Factors for violence risk (SAPROF) was recently developed as a strength-based addition to the risk assessment of future violent behavior. We examined the interrater reliability and predictive accuracy of the SAPROF for violence in forensic mental health inpatient units in Japan. Methods: This retrospective record study provides an initial validation of the SAPROF in a Japanese sample of 95 forensic psychiatric inpatients from a complete 2008-2013 cohort...
2018: Annals of General Psychiatry
https://www.readbyqxmd.com/read/29410698/suicide-ideation-and-attempts-among-people-with-epilepsy-in-addis-ababa-ethiopia
#14
Kelelemua Haile, Tadesse Awoke, Getnet Ayano, Minale Tareke, Andargie Abate, Mulugeta Nega
Background: Suicidal ideation and attempts are more frequent in people with epilepsy than in general population and suicide attempt increases the chance of later completed suicide. The aim of this study was to assess the prevalence and associated factors of suicidal ideation and attempt among people with epilepsy in Amanuel Mental Specialized Hospital, Addis Ababa, Ethiopia. Methods: Institution-based cross-sectional study was conducted from May to June 2014 at Amanuel Mental Specialized Hospital among people with epilepsy...
2018: Annals of General Psychiatry
https://www.readbyqxmd.com/read/29371875/psychopathology-of-addiction-can-the-scl90-based-five-dimensional-structure-differentiate-heroin-use-disorder-from-a-non-substance-related-addictive-disorder-such-as-gambling-disorder
#15
Angelo G I Maremmani, Denise Gazzarrini, Amelia Fiorin, Valeria Cingano, Graziano Bellio, Giulio Perugi, Icro Maremmani
Background: In the Gambling Disorder (GD), there is no exogenous drug administration that acts as the central core of the traditional meaning of addiction. A specific psychopathology of Substance Use Disorders has been proposed recently. In a sample of Heroin Use Disorder (HUD) patients entering opioid agonist treatment, it became possible to identify a group of 5 mutually exclusive psychiatric dimensions: Worthlessness-Being trapped (W-BT), Somatic Symptoms (SS), Sensitivity-Psychoticism (SP), Panic Anxiety (PA) and Violence-Suicide (VS)...
2018: Annals of General Psychiatry
https://www.readbyqxmd.com/read/29299043/the-efficacy-acceptability-and-safety-of-five-atypical-antipsychotics-in-patients-with-first-episode-drug-na%C3%A3-ve-schizophrenia-a-randomized-comparative-trial
#16
Congjie Wang, Wenjie Shi, Chengbing Huang, Jiannan Zhu, Wenzhong Huang, Gang Chen
Background: Differences in effectiveness and tolerability between different atypical antipsychotics may affect schizophrenic patients' treatment adherence or prognosis. However, which kind of antipsychotic was more effective and safe in the treatment of schizophrenia is still being debated. This study attempted to understand whether there are any differences in efficacy, acceptability, and safety between the five atypical antipsychotics in patients with first-episode schizophrenia. Methods: Two hundred cases of inpatients with first-episode drug-naïve schizophrenia were randomly assigned to 6-8 weeks of treatment with either of aripiprazole, risperidone, quetiapine, olanzapine, or ziprasidone from October 2012 to November 2014...
2017: Annals of General Psychiatry
https://www.readbyqxmd.com/read/29259655/continuation-with-clozapine-after-eosinophilia-a-case-report
#17
Yen-Cheng Ho, Huang-Li Lin
Background: Clozapine-induced eosinophilia had been reported in several studies about blood dyscrasias in clozapine-treated patient. The largest study with 2404 patients in Italy found the incidence of 2.2% by criteria of more than 0.4 × 109 /l. Associated cases of pancreatitis, hepatitis, colitis, nephritis, and myocarditis were reported. Interestingly, incidence of myocarditis is high in Australia, but low in the rest of the world. In the following, we will present a case of clozapine-induced eosinophilia which spontaneous resolution was noted under continuation of clozapine...
2017: Annals of General Psychiatry
https://www.readbyqxmd.com/read/29234453/an-association-study-of-taq1a-ankk1-and-c957t-and-141c-drd2-polymorphisms-in-adults-with-internet-gaming-disorder-a-pilot-study
#18
Soo-Hyun Paik, Mi Ran Choi, Su Min Kwak, Sol Hee Bang, Ji-Won Chun, Jin-Young Kim, Jihye Choi, Hyun Cho, Jo-Eun Jeong, Dai-Jin Kim
Background: Though Internet gaming disorder (IGD) is considered to share similar genetic vulnerability with substance addictions, little has been explored about the role of the genetic variants on IGD. This pilot study was designed to investigate the association of the Taq1A polymorphism of the ankyrin repeat and kinase domain containing 1 ( ANKK1 ) gene and C957T and -  141C of the dopamine D2 receptor ( DRD2 ) with IGD and their role on the personality and temperament traits in IGD among adult population...
2017: Annals of General Psychiatry
https://www.readbyqxmd.com/read/29213296/comparison-of-the-characteristics-of-suicide-attempters-with-major-depressive-disorder-and-those-with-no-psychiatric-diagnosis-in-emergency-departments-of-general-hospitals-in-china
#19
Shengnan Wei, Haiyan Li, Jinglin Hou, Wei Chen, Xu Chen, Xiaoxia Qin
Background: Major depressive disorder (MDD) is a known major risk factor for suicide due to the high suicide mortality. However, studies comparing the characteristics of suicide attempters with major depressive disorder and those with no psychiatric diagnosis in China are very limited. This study examined and compared the sociodemographic and psychological characteristics of suicide attempters with MDD and those with no psychiatric diagnosis in emergency departments of general hospitals to better understand the risk factors for suicide attempts in China...
2017: Annals of General Psychiatry
https://www.readbyqxmd.com/read/29209406/serum-prolactin-levels-and-sexual-dysfunction-in-patients-with-schizophrenia-treated-with-antipsychotics-comparison-between-aripiprazole-and-other-atypical-antipsychotics
#20
Eiji Kirino
Objectives: Antipsychotics, even atypical ones, can induce hyperprolactinemia. Aripiprazole (APZ), a dopamine D2 partial agonist, has a unique pharmacological profile and few side effects. We investigated the incidence of hyperprolactinemia in patients with schizophrenia treated with APZ and other antipsychotics. Methods: Serum prolactin levels were measured by ELISA (enzyme-linked immunosorbent assay). A questionnaire survey was used to evaluate subjective sexual dysfunction...
2017: Annals of General Psychiatry
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