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Forensic Science, Medicine, and Pathology

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https://www.readbyqxmd.com/read/28526950/the-effect-of-post-mortem-computed-tomography-angiography-pmcta-using-water-soluble-iodine-based-radiographic-contrast-on-histological-analysis-of-the-liver-kidneys-and-left-ventricle-of-the-heart
#1
Samantha Higgins, Sarah Parsons, Noel Woodford, Matthew Lynch, Christopher Briggs, Chris O'Donnell
The purpose of this study was to investigate the impact of post-mortem computed-tomography angiography (PMCTA) on the histology of the liver, kidneys and heart. Multiple tissue cores were collected from the liver, left and right kidneys and left ventricle utilizing CT-guided biopsy. Subsequent whole body PMCTA was performed using a solution of polyethylene glycol and iodinated radiographic contrast, and an embalming pump. Corresponding biopsy cores were collected at autopsy, and blinded histology analysis assessing for PMCTA-induced histology artefact was performed...
May 20, 2017: Forensic Science, Medicine, and Pathology
https://www.readbyqxmd.com/read/28526949/antemortem-identification-by-fusion-of-mr-and-ct-of-the-paranasal-sinuses
#2
Jakob Heimer, Dominic Gascho, Simon Gentile, Gary M Hatch, Michael J Thali, Thomas D Ruder
Radiologic forensic identification is usually performed by comparing antemortem and postmortem radiographs. While computed tomography (CT) has become a valuable addition to radiologic identification, magnetic resonance (MR) imaging has only rarely been used for this purpose. In our case, identification was accomplished using fused MR- and CT images in a survivor of a gunshot injury to the head. This case supports and highlights the possibility to perform intermodality radiologic identification comparing preexisting MR imaging to subsequently aquired CT data in living (or deceased) humans as long as manual modifications of windowing, color and contrast enable differentiation of the two modalities in the fused image...
May 20, 2017: Forensic Science, Medicine, and Pathology
https://www.readbyqxmd.com/read/28523436/hrm-and-snapshot-as-alternative-forensic-snp-genotyping-methods
#3
Bhavik Mehta, Runa Daniel, Dennis McNevin
Single nucleotide polymorphisms (SNPs) have been widely used in forensics for prediction of identity, biogeographical ancestry (BGA) and externally visible characteristics (EVCs). Single base extension (SBE) assays, most notably SNaPshot® (Thermo Fisher Scientific), are commonly used for forensic SNP genotyping as they can be employed on standard instrumentation in forensic laboratories (e.g. capillary electrophoresis). High resolution melt (HRM) analysis is an alternative method and is a simple, fast, single tube assay for low throughput SNP typing...
May 18, 2017: Forensic Science, Medicine, and Pathology
https://www.readbyqxmd.com/read/28523435/cutaneous-manifestations-of-lightning-strike-variability-in-lichtenberg-figures
#4
Roger W Byard, Min Thu, John D Gilbert
No abstract text is available yet for this article.
May 18, 2017: Forensic Science, Medicine, and Pathology
https://www.readbyqxmd.com/read/28497353/ian-freckelton-qc-scholarly-misconduct-law-regulation-and-practice-oxford-university-press-2016-isbn-978-0-19-875-540-1
#5
Roger W Byard
No abstract text is available yet for this article.
May 11, 2017: Forensic Science, Medicine, and Pathology
https://www.readbyqxmd.com/read/28493014/commentary-on-a-case-of-body-pushing-and-radiation-exposure-in-screening-of-body-packing
#6
LETTER
Simone Cappelletti, Costantino Ciallella
No abstract text is available yet for this article.
May 10, 2017: Forensic Science, Medicine, and Pathology
https://www.readbyqxmd.com/read/28466139/forensic-aspects-of-gene-expression-signatures-for-age-determination-in-bruises-as-evaluated-in-an-experimental-porcine-model
#7
Kristiane Barington, Henrik Elvang Jensen, Kerstin Skovgaard
Determining the age of bruises and the force used to inflict the trauma is of crucial importance in both human and veterinary forensic pathology. In the present study, the expression of more than 50 different genes in subcutaneous fat and muscle tissue from experimental bruises in pigs was investigated. The aim was to evaluate if expression signatures of selected genes were capable of determining bruises according to age and the force of impact. Eighteen experimental pigs were anesthetized, and on each animal four blunt traumas were inflicted on the back with a low, moderate or high force...
May 2, 2017: Forensic Science, Medicine, and Pathology
https://www.readbyqxmd.com/read/28444619/the-reference-cube-a-new-ballistic-model-to-generate-staining-in-firearm-barrels
#8
Christian Schyma, Kristina Bauer, Julia Brünig
After contact shots to the head biological traces can be found inside firearm barrels. So far silicone coated, gelatin filled box models were used to generate such staining according to the triple contrast method (mixture of acrylic paint, barium sulfate and blood sealed in a thin foil bag). This study was conducted to develop a transparent ballistic model allowing contact shots. Gelatin filled polyethylene bottles with and without a silicone coat were tested in comparison to non-covered gelatin blocks. Finally, thin foil bags of 5 cm × 5 cm dimension were glued on a synthetic absorbent kitchen wipe on top of which 1 L 10% gelatin solution was molded to create blocks of 8...
April 25, 2017: Forensic Science, Medicine, and Pathology
https://www.readbyqxmd.com/read/28444618/rna-dna-co-analysis-on-aged-bloodstains-from-adhesive-tapes-used-for-gunshot-residue-collection-from-hands
#9
Melanie Grabmüller, Christian Schyma, Burkhard Madea, Tim Eichhorst, Cornelius Courts
In cases of firearm related fatalities a systematic investigation at the scene of death is indispensable to differentiate between self-inflicted and homicidal gunshot injuries. A common method to preserve gunshot residues (GSR) is their collection using adhesive tapes. However, the biological material gathered at the same time by the tapes would be of special interest if backspatter, ejected from the entrance wound against the direction of fire, could be detected. In the present study we examined the success rate of co-analysis of RNA and DNA recovered from biological traces sampled with adhesive tapes...
April 25, 2017: Forensic Science, Medicine, and Pathology
https://www.readbyqxmd.com/read/28439786/a-panel-of-130-autosomal-single-nucleotide-polymorphisms-for-ancestry-assignment-in-five-asian-populations-and-in-caucasians
#10
Hsiao-Lin Hwa, Chih-Peng Lin, Tsun-Ying Huang, Po-Hsiu Kuo, Wei-Hsin Hsieh, Chun-Yen Lin, Hsiang-I Yin, Li-Hui Tseng, James Chun-I Lee
Ancestry informative single-nucleotide polymorphism (AISNP) panels for differentiating between East and Southeast Asian populations are scarce. This study aimed to identify AISNPs for ancestry assignment of five East and Southeast Asian populations, and Caucasians. We analyzed 145 autosomal SNPs of the 627 DNA samples from individuals of six populations (234 Taiwanese Han, 91 Filipinos, 79 Indonesians, 60 Thais, 71 Vietnamese, and 92 Caucasians) using arrays. The multiple logistic regression model and a multi-tier approach were used for ancestry classification...
April 24, 2017: Forensic Science, Medicine, and Pathology
https://www.readbyqxmd.com/read/28409387/fatal-abdominal-injuries-in-a-bicycle-pedestrian-collision-reconstruction-using-multibody-simulation
#11
Holger Muggenthaler, Stefanie Drobnik, Michael Hubig, Wolfgang Fiebig, Gita Mall
Fatal bicycle-pedestrian collisions do not occur frequently and thus are rarely reported in literature. Pedestrians in bicycle-pedestrian accidents often sustain severe craniocerebral injuries caused by a collision induced fall with head impact on the road surface. We describe a case where a pedestrian crossing a road was hit by a bicycle. Hematomas of the left lower leg and of the left flank/abdomen were found to be caused by the primary impact. However, the fatal injuries were found to be contralateral with a rupture of the right renal pedicle, a rupture of the right lobe of the liver and a tear of the vena cava...
April 13, 2017: Forensic Science, Medicine, and Pathology
https://www.readbyqxmd.com/read/28409386/nocturnal-oviposition-behavior-of-blowflies-diptera-calliphoridae-in-the-southern-hemisphere-south-africa-and-australia-and-its-forensic-implications
#12
Kirstin A Williams, James F Wallman, Bryan D Lessard, Christopher R J Kavazos, D Nkosinathi Mazungula, Martin H Villet
Published research has offered contradictory evidence of the occurrence of nocturnal oviposition by carrion-breeding blowflies, a behavior that can affect the interpretation of forensic estimates of a minimum post mortem interval (minPMI) by up to 12 hours, depending on latitude and season. The majority of published studies are from the northern hemisphere. Field experiments were conducted in South Africa and Australia that extend observations to species of the southern hemisphere. Various vertebrate carrion was exposed at night in summer under different lunar phases and/or artificial lighting, and in woodland and pasture areas...
April 13, 2017: Forensic Science, Medicine, and Pathology
https://www.readbyqxmd.com/read/28405885/sudden-death-due-to-catecholaminergic-polymorphic-ventricular-tachycardia-following-negative-stress-test-outcome-genetics-and-clinical-implications
#13
Cristian D'Ovidio, Aldo Carnevale, Vincenzo M Grassi, Enrica Rosato, Bernat Del Olmo, Monica Coll, Oscar Campuzano, Anna Iglesias, Ramon Brugada, Antonio Oliva
This paper discusses the case of a young boy who died suddenly during a football match. The victim's personal and family medical histories were negative for cardiac events. He had undergone a cardiological investigation some months before his death, enabling him to participate in competitive sports. Only post-mortem molecular analysis allowed for a clearer determination of the most plausible cause of death, which was identified as inherited arrhythmogenic heart disease, known as catecholaminergic polymorphic ventricular tachycardia...
April 13, 2017: Forensic Science, Medicine, and Pathology
https://www.readbyqxmd.com/read/28405884/response-to-regarding-the-sudden-death-of-a-juvenile-with-rare-tdt-negative-t-lbl-t-all-splenic-rupture-and-mediastinal-mass
#14
LETTER
Dominic Gascho, Sarah Schaerli, Michael J Thali, Stephan A Bolliger
No abstract text is available yet for this article.
April 12, 2017: Forensic Science, Medicine, and Pathology
https://www.readbyqxmd.com/read/28401335/fatal-bronchovascular-fistula-after-lobectomy-visualized-through-postmortem-computed-tomography-angiography-a-case-report
#15
Philipp Hinderberger, Barbara Fliss, Michael J Thali, Wolf Schweitzer
False aneurysm of the pulmonary artery complicated by bronchovascular fistula formation represents a rare life threating condition. We report a case of fatal hemoptysis after formation of a bronchial fistula in the late postoperative period after sleeve lobectomy. Cause of death was determined by external postmortem examination, post mortem computed tomography (PMCT) and angiography (PMCTA) without conventional autopsy.
April 11, 2017: Forensic Science, Medicine, and Pathology
https://www.readbyqxmd.com/read/28352989/electric-fences-and-accidental-death
#16
Michael Burke, Morris Odell, Heinrich Bouwer, Adam Murdoch
Deaths which occur in association with agricultural electric fences are very rare. In fact, electric fences have undoubtedly saved numerous human and animal lives by safely and reliably keeping livestock confined to their fields and enclosures and thus preventing motor vehicle incidents when livestock get onto roads and highways. Accidental and intentional human contact with electric fences occurs regularly and causes little more than transient discomfort, however, on exceptional occasions, contact with electric fences appears to be directly related to the death of the individual...
March 28, 2017: Forensic Science, Medicine, and Pathology
https://www.readbyqxmd.com/read/28352988/differentiation-of-hemopericardium-due-to-ruptured-myocardial-infarction-or-aortic-dissection-on-unenhanced-postmortem-computed-tomography
#17
Garyfalia Ampanozi, Patricia M Flach, Thomas D Ruder, Laura Filograna, Wolf Schweitzer, Michael J Thali, Lars C Ebert
The aim of the study was to evaluate unenhanced postmortem computed tomography (PMCT) in cases of non-traumatic hemopericardium by establishing the sensitivity, specificity and accuracy of diagnostic criteria for the differentiation between aortic dissection and myocardial wall rupture due to infarction. Twenty six cases were identified as suitable for evaluation, of which ruptured aortic dissection could be identified as the underlying cause of hemopericardium in 50% of the cases, and myocardial wall rupture also in 50% of the cases...
March 28, 2017: Forensic Science, Medicine, and Pathology
https://www.readbyqxmd.com/read/28352987/hemolytic-uremic-syndrome-caused-by-e-coli-o157-infection
#18
Philip V Bystrom, Robert J Beck, Joseph A Prahlow
No abstract text is available yet for this article.
March 28, 2017: Forensic Science, Medicine, and Pathology
https://www.readbyqxmd.com/read/28349246/suicide-patterns-in-children-and-adolescents-a-review-from-a-pediatric-institution-in-england
#19
Khairul Zainum, Marta C Cohen
Suicide is a catastrophic event to both families and communities yet it is potentially preventable. This study aims to determine incidence and patterns of suicide in children and young adolescents in our region, raise awareness of this entity as a potentially preventable cause of death in this age group, and identify its possible associated risk factors. We retrospectively reviewed suicide cases presenting as sudden unexpected death in children and adolescents that underwent coronial post-mortems at our institution...
March 27, 2017: Forensic Science, Medicine, and Pathology
https://www.readbyqxmd.com/read/28343286/a-mimic-of-sexually-motivated-homicide-insect-stings-and-heat-exhaustion-in-a-forest
#20
Nancy X Liu, Michael S Pollanen
We report the case a woman who was found dead in a forest. The body was nude and the position of the body suggested a sexually motivated homicide. We concluded that death was not related to homicide, but was related to the conjunction of environmental factors, including insect stings, and acute psychosis. A medicolegal death investigation with postmortem examination was undertaken to determine cause of death. At the scene, the body was supine with legs spread apart and the knees flexed, exposing the external genitalia...
March 25, 2017: Forensic Science, Medicine, and Pathology
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