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Current HIV/AIDS Reports

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https://www.readbyqxmd.com/read/30259258/a-missing-link-hiv-aids-related-mhealth-interventions-for-health-workers-in-low-and-middle-income-countries
#1
REVIEW
Sarah Gimbel, Nami Kawakyu, Hallie Dau, Jennifer A Unger
PURPOSE OF REVIEW: Through a review of the peer-reviewed and gray literature on HIV mobile health (mHealth) tools for health workers and in-depth interviews with mHealth leaders in the field, we provide a synthesis of current work and propose mHealth research priorities for HIV prevention, care, and treatment. RECENT FINDINGS: Significant investment in implementation research and bringing together researchers capable of identifying drivers of successful implementation and industry leaders capable of bringing efficacious tools to scale are needed to move this area forward...
September 26, 2018: Current HIV/AIDS Reports
https://www.readbyqxmd.com/read/30232579/ehealth-for-stigma-reduction-efforts-designed-to-improve-engagement-in-care-for-people-living-with-hiv
#2
REVIEW
Deepa Rao, Sarah Frey, Megan Ramaiya
PURPOSE OF REVIEW: HIV-related stigma remains a significant barrier to engagement in care for persons living with HIV (PLWH) worldwide. This review examines the use of eHealth technologies for reducing stigma as a pathway toward improved engagement in care for PLWH. We provide a brief overview of effective stigma reduction interventions for PLWH, both eHealth and others; identify gaps in the research on use of eHealth technologies for stigma reduction; and suggest potential research avenues moving forward...
September 19, 2018: Current HIV/AIDS Reports
https://www.readbyqxmd.com/read/30218255/human-genetic-variation-and-hiv-aids-in-papua-new-guinea-time-to-connect-the-dots
#3
REVIEW
Rajeev K Mehlotra
PURPOSE OF REVIEW: Human genetic polymorphisms known to influence HIV acquisition and disease progression occur in Papua New Guinea (PNG). However, no genetic association study has been reported so far. In this article, we review research findings, with a view to stimulate genotype-to-phenotype research. RECENT FINDINGS: PNG, a country in Oceania, has a high prevalence of HIV and many sexually transmitted infections. While limited data is available from this country regarding the distribution of human genetic polymorphisms known to influence clinical outcomes of HIV/AIDS, genetic association studies are lacking...
September 14, 2018: Current HIV/AIDS Reports
https://www.readbyqxmd.com/read/30171519/implementation-of-ehealth-interventions-across-the-hiv-care-cascade-a-review-of-recent-research
#4
REVIEW
Christopher G Kemp, Jennifer Velloza
PURPOSE OF REVIEW: We review recent implementation science focusing on eHealth interventions to improve outcomes along the HIV care cascade. We highlight several gaps in the eHealth implementation literature and propose areas for future study. RECENT FINDINGS: We identified 17 studies conducted in North America, Europe, and sub-Saharan Africa assessing the acceptability, appropriateness, adoption, cost, feasibility, fidelity, penetration, or sustainability of eHealth interventions targeting the HIV care cascade...
September 1, 2018: Current HIV/AIDS Reports
https://www.readbyqxmd.com/read/30232578/actionable-adherence-monitoring-technological-methods-to-monitor-and-support-adherence-to-antiretroviral-therapy
#5
REVIEW
Kate M Bell, Jessica E Haberer
PURPOSE OF REVIEW: Current digital technologies are being used for "actionable adherence monitoring"; that is, technologies that can be used to identify episodes of non-adherence to ART in a timely manner such that tailored interventions based on adherence data can be provided when and where they are needed most. RECENT FINDINGS: Current digital communication technologies used to monitor ART adherence include electronic adherence monitors (EAMs), digital ingestion monitors, cellular phones, and electronic pharmacy refill tracking systems...
October 2018: Current HIV/AIDS Reports
https://www.readbyqxmd.com/read/30159813/cns-persistence-of-hiv-1-in-children-the-untapped-reservoir
#6
REVIEW
Ann Chahroudi, Thor A Wagner, Deborah Persaud
PURPOSE OF REVIEW: The central nervous system (CNS) represents a potential HIV-1 reservoir that may need to be specifically targeted by remission strategies. Perinatally HIV-1-infected children and youth are exposed to HIV-1 at a critical period of brain development. This review summarizes the current literature regarding HIV-1 and the CNS in perinatal infection. RECENT FINDINGS: HIV-1-associated encephalopathy is prevalent with perinatal infection and neurocognitive impairment persists even following antiretroviral treatment (ART)-mediated suppression of viremia...
October 2018: Current HIV/AIDS Reports
https://www.readbyqxmd.com/read/30069724/a-dissemination-and-implementation-science-approach-to-the-epidemic-of-opioid-use-disorder-in-the-united-states
#7
REVIEW
Stephanie M Mathis, Nicholas Hagemeier, Angela Hagaman, John Dreyzehner, Robert P Pack
PURPOSE OF REVIEW: This review aims to (1) conceptualize the complexity of the opioid use disorder epidemic using a conceptual model grounded in the disease continuum and corresponding levels of prevention and (2) summarize a select set of interventions for the prevention and treatment of opioid use disorder. RECENT FINDINGS: Epidemiologic data indicate non-medical prescription and illicit opioid use have reached unprecedented levels, fueling an opioid use disorder epidemic in the USA...
October 2018: Current HIV/AIDS Reports
https://www.readbyqxmd.com/read/30058057/inflammation-and-metabolic-complications-in-hiv
#8
REVIEW
Kassem Bourgi, Celestine Wanjalla, John R Koethe
PURPOSE OF REVIEW: We aim to provide an in-depth review of recent literature highlighting the role of inflammation involving the adipose tissue, liver, skeletal muscles, and gastrointestinal tract in the development of metabolic complications among persons living with HIV (PLWH). RECENT FINDINGS: Recent studies in PLWH have demonstrated a significant association between circulating inflammatory markers and development of insulin resistance and metabolic complications...
October 2018: Current HIV/AIDS Reports
https://www.readbyqxmd.com/read/29968173/federal-response-to-the-opioid-crisis
#9
REVIEW
Kimberly Johnson, Chris Jones, Wilson Compton, Grant Baldwin, Jennifer Fan, Jonathan Mermin, Jean Bennett
PURPOSE OF REVIEW: In light of the current crisis in opioid involved overdose deaths, the federal Department of Health and Human Services operating divisions are working together to implement a data-driven, research-based strategy to reduce opioid misuse and its consequences. RECENT FINDINGS: The strategy has five elements: (1) strengthening public health data collection and reporting; (2) advancing the practice of pain management; (3) improving access to addiction prevention, treatment, and recovery support services; (4) increasing availability of overdose-reversing drugs; and (5) supporting cutting-edge research in treatment of pain, opioid use disorder, and associated conditions...
August 2018: Current HIV/AIDS Reports
https://www.readbyqxmd.com/read/29959649/ehealth-to-enhance-treatment-adherence-among-youth-living-with-hiv
#10
REVIEW
Marta I Mulawa, Sara LeGrand, Lisa B Hightow-Weidman
PURPOSE OF REVIEW: Multiple reviews have examined eHealth/mHealth interventions to address treatment adherence, including those focusing on youth living with HIV (YLWH). This review synthesizes results of prior reviews and recent studies (last 5 years) to provide a path forward for future research, acknowledging both lessons learned and gaps to be addressed. RECENT FINDINGS: Recent studies provide further evidence for the feasibility and acceptability of technology-based HIV interventions...
August 2018: Current HIV/AIDS Reports
https://www.readbyqxmd.com/read/29948610/working-with-persons-who-inject-drugs-and-live-in-rural-areas-implications-from-china-vietnam-for-the-usa
#11
REVIEW
Don C Des Jarlais, Theodore M Hammett, Binh Kieu, Yi Chen, Jonathan Feelemyer
PURPOSE OF REVIEW: To describe a small city/rural area HIV prevention project (the Cross Border Project) implemented in Ning Ming County, Guangxi Province, China, and Lang Son province, Vietnam, and consider its implications for addressing the opioid/heroin epidemic in small cities/rural areas in the USA. The description and the outcomes of the Cross Border project were taken from published reports, project records, and recent data provided by local public health authorities. Evaluation included serial cross-sectional surveys of people who inject drugs to assess trends in risk behaviors and HIV prevalence...
August 2018: Current HIV/AIDS Reports
https://www.readbyqxmd.com/read/29948609/implementing-treatment-of-opioid-use-disorder-in-rural-settings-a-focus-on-hiv-and-hepatitis-c-prevention-and-treatment
#12
REVIEW
Jennifer R Havens, Sharon L Walsh, P Todd Korthuis, David A Fiellin
PURPOSE OF REVIEW: To describe the epidemiology of opioid-use disorder in the rural United States (U.S.) as it pertains to HIV and hepatitis C transmission and treatment resources. RECENT FINDINGS: Heroin and fentanyl analogs have surpassed prescription opioids in their availability in rural opioid markets adding to HIV and hepatitis C (HCV) and overdose risks. Only 18% of rural individuals live in towns with inpatient services which are of limited quality and utility...
August 2018: Current HIV/AIDS Reports
https://www.readbyqxmd.com/read/29931468/young-drug-users-a-vulnerable-population-and-an-underutilized-resource-in-hiv-hcv-prevention
#13
REVIEW
Pedro Mateu-Gelabert, H Guarino, K Quinn, P Meylakhs, S Campos, A Meylakhs, D Berbesi, D Toro-Tobón, E Goodbody, D C Ompad, S R Friedman
PURPOSE OF REVIEW: The social networks of people who inject drugs (PWID) have long been studied to understand disease transmission dynamics and social influences on risky practices. We illustrate how PWID can be active agents promoting HIV, HCV, and overdose prevention. RECENT FINDINGS: We assessed drug users' connections and interactions with others at risk for HIV/HCV in three cities: New York City (NYC), USA (n = 539); Pereira, Colombia (n = 50); and St...
June 22, 2018: Current HIV/AIDS Reports
https://www.readbyqxmd.com/read/29931467/ehealth-and-prevention-of-mother-to-child-transmission-of-hiv
#14
REVIEW
Grace John-Stewart
PURPOSE OF REVIEW: The goal of this paper is to describe areas in prevention of mother-to-child transmission of HIV (PMTCT) programs that could benefit from ehealth and to summarize current evidence of ehealth effectiveness in PMTCT. RECENT FINDINGS: PMTCT programs require maternal retention, adherence to antiretroviral treatment (ART), and return for infant diagnosis of HIV. eHealth systems for PMTCT could either be integrated within MCH ehealth systems or within HIV adherence ehealth systems...
June 22, 2018: Current HIV/AIDS Reports
https://www.readbyqxmd.com/read/29931466/hiv-hcv-co-infection-burden-of-disease-and-care-strategies-in-appalachia
#15
REVIEW
Jonathan P Moorman, Matthew R Krolikowski, Stephanie M Mathis, Robert P Pack
PURPOSE OF REVIEW: The purpose of this review is to address infection with HIV and hepatitis C in the Appalachian region of the USA and the driving forces underlying this epidemic. We seek to discuss epidemiology of disease and the possible interventions to reduce incidence and burden of disease in this resource-limited area. RECENT FINDINGS: The rise of the opioid crisis has fueled a rise in new hepatitis C infection, and a rise in new HIV infection is expected to follow...
June 21, 2018: Current HIV/AIDS Reports
https://www.readbyqxmd.com/read/29905915/network-research-experiences-in-new-york-and-eastern-europe-lessons-for-the-southern-us-in-understanding-hiv-transmission-dynamics
#16
REVIEW
Samuel R Friedman, Leslie Williams, April M Young, Jennifer Teubl, Dimitrios Paraskevis, Evangelia Kostaki, Carl Latkin, Danielle German, Pedro Mateu-Gelabert, Honoria Guarino, Tetyana I Vasylyeva, Britt Skaathun, John Schneider, Ania Korobchuk, Pavlo Smyrnov, Georgios Nikolopoulos
PURPOSE: This paper presents an overview of different kinds of risk and social network methods and the kinds of research questions each can address. RECENT FINDINGS: It also reviews what network research has discovered about how network characteristics are associated with HIV and other infections, risk behaviors, preventive behaviors, and care, and discusses some ways in which network-based public health interventions have been conducted. Based on this, risk and social network research and interventions seem both feasible and valuable for addressing the many public health and social problems raised by the widespread use of opioids in the US South...
June 2018: Current HIV/AIDS Reports
https://www.readbyqxmd.com/read/29796965/challenges-facing-a-rural-opioid-epidemic-treatment-and-prevention-of-hiv-and-hepatitis-c
#17
REVIEW
Asher J Schranz, Jessica Barrett, Christopher B Hurt, Carlos Malvestutto, William C Miller
PURPOSE OF REVIEW: This article reviews recent epidemiologic trends in HIV and hepatitis C virus (HCV) and strategies for treatment and prevention of these infections as they relate to the opioid epidemic. RECENT FINDINGS: Among people who inject drugs (PWID) in the United States (US), HIV diagnoses are decreasing, while HCV is increasing. Care for HIV and HCV relies heavily on specialist infrastructure, which is lacking in rural areas. Antiretrovirals for HIV and direct-acting antivirals for HCV are effective among PWID, yet multiple barriers make it difficult for rural injectors to access these treatments...
June 2018: Current HIV/AIDS Reports
https://www.readbyqxmd.com/read/29774442/integrated-models-of-care-for-individuals-with-opioid-use-disorder-how-do-we-prevent-hiv-and-hcv
#18
REVIEW
Katherine M Rich, Joshua Bia, Frederick L Altice, Judith Feinberg
PURPOSE OF REVIEW: To describe models of integrated and co-located care for opioid use disorder (OUD), hepatitis C (HCV), and HIV. RECENT FINDINGS: The design and scale-up of multidisciplinary care models that engage, retain, and treat individuals with HIV, HCV, and OUD are critical to preventing continued spread of HIV and HCV. We identified 17 models within primary care (N = 3), HIV specialty care (N = 5), opioid treatment programs (N = 6), transitional clinics (N = 2), and community-based harm reduction programs (N = 1), as well as two emerging models...
June 2018: Current HIV/AIDS Reports
https://www.readbyqxmd.com/read/29713871/continued-interest-and-controversy-vitamin-d-in-hiv
#19
REVIEW
Evelyn Hsieh, Michael T Yin
PURPOSE OF REVIEW: Vitamin D (VitD) deficiency is highly prevalent among HIV-infected individuals. Given the overlapping risk for several chronic disease and immunomodulatory outcomes from both long-standing HIV and VitD deficiency, there is great interest in clarifying the clinical role of VitD for this population. RECENT FINDINGS: Recent studies have expanded our knowledge regarding the epidemiology and mechanisms of VitD deficiency-associated outcomes in the setting of HIV...
June 2018: Current HIV/AIDS Reports
https://www.readbyqxmd.com/read/29700760/factors-associated-with-insulin-resistance-in-adults-with-hiv-receiving-contemporary-antiretroviral-therapy-a-brief-update
#20
REVIEW
Todd Hulgan
PURPOSE OF REVIEW: This narrative review summarizes recent data on factors associated with insulin resistance (IR) in adults with HIV, including contemporary antiretroviral therapy (ART). RECENT FINDINGS: IR remains common in persons with HIV, even those receiving contemporary ART. Generalized and abdominal obesity and ectopic fat are correlates of IR, and emerging data have identified associations with biomarkers of inflammation and immune activation. Small studies suggest associations between mitochondria and IR...
June 2018: Current HIV/AIDS Reports
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