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Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences

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https://www.readbyqxmd.com/read/29937910/platelet-distribution-width-as-a-novel-indicator-of-disease-activity-in-systemic-lupus-erythematosus
#1
Sun-Yi Chen, Juan Du, Xiao-Nian Lu, Jin-Hua Xu
Background: Significance of platelet distribution width (PDW) and mean platelet volume (MPV) in assessing disease activity of systemic lupus erythematosus (SLE) remains unclear. This study was aimed to evaluate PDW and MPV as potential disease activity markers in adult SLE patients. Materials and Methods: A total of 204 study participants, including 91 SLE patients and 113 age- and gender-matched healthy controls, were selected in this cross-sectional study. They were classified into three groups: control group ( n = 113), active SLE group ( n = 54), and inactive SLE group ( n = 37)...
2018: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/29937909/the-effect-of-fads2-gene-rs174583-polymorphism-on-desaturase-activities-fatty-acid-profile-insulin-resistance-biochemical-indices-and-incidence-of-type-2-diabetes
#2
Leila Mazoochian, Hamid Mir Mohammad Sadeghi, Morteza Pourfarzam
Background: In this study, we investigated the associations of erythrocytes fatty acid composition, activities of delta-5 desaturase (D5D) and delta-6 desaturase (D6D), and other metabolic risk factors, with type 2 diabetes (T2D) risk to determine if rs174583 polymorphism of FADS2 gene had any effect on these associations. Materials and Methods: Fatty acid profile of erythrocytes was determined using gas chromatography-mass spectrometry in 95 T2D patients and 95 apparently healthy participants...
2018: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/29937908/hyperimmunoglobulin-e-syndrome
#3
Javad Ghaffari
No abstract text is available yet for this article.
2018: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/29937907/full-colonoscopy-in-patients-under-50-years-old-with-lower-gastrointestinal-bleeding
#4
Mahsa Khodadoostan, Ahmad Shavakhi, Reihaneh Padidarnia, Alireza Shavakhi, Mehdi Ahmadian
Background: Lower gastrointestinal (GI) bleeding is a common clinical problem in young patients. The management of this disease in patients is challenging. The aim of this study is to compare sigmoidoscopy with full colonoscopy in these patients. Materials and Methods: In this cross-sectional study, 120 eligible patients under 50 years old with acute rectal bleeding were enrolled. After cleaning the colon, initially the patients underwent sigmoidoscopy. Pain, the comfort of the test by physician and patient, duration of the procedure, and pathologic findings were recorded...
2018: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/29937906/retinol-binding-protein-4-versus-albuminuria-as-predictors-of-estimated-glomerular-filtration-rate-decline-in-patients-with-type-2-diabetes
#5
Aleksandra Klisic, Nebojsa Kavaric, Ana Ninic
Background: Since the increase in some tubular damage biomarkers can be observed at the early stage of diabetic nephropathy, even in the absence of albuminuria, we aimed to investigate if urinary albumin is superior than tubular damage marker, such as serum retinol-binding protein 4 (RBP4), in predicting renal function decline (defined as estimated glomerular filtration rate [eGFR] <60 mL/min/1.73 m2 ) in the cohort of patients with type 2 diabetes mellitus (T2D). Materials and Methods: A total of 106 sedentary T2D patients (mean [± standard deviation] age 64...
2018: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/29937905/advanced-glycation-end-products-and-risk-of-hypertension-in-iranian-adults-tehran-lipid-and-glucose-study
#6
Parvin Mirmiran, Reyhaneh Yousefi, Azadeh Mottaghi, Fereidoun Azizi
Background: Elevated blood pressure is still one of the major risk factors for diseases and disabilities and also a public health challenge worldwide. In the present longitudinal study, we aimed to evaluate the association between risk of hypertension and dietary advanced glycation end products (AGEs) as a recently discussed potential risk factor. Materials and Methods: Dietary assessment of 1775 participants in the third phase of Tehran lipid and glucose study to obtain dietary intake of AGEs was performed using a validated semi-quantitative food frequency questionnaire, and they were followed up for a mean duration of approximately 6 years...
2018: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/29937904/hla-drb1-gene-polymorphisms-in-iranian-children-with-henoch-sch%C3%A3-nlein-purpura
#7
Saadyeh Rashidi, Reza Shiari, Shirin Farivar
Background: People of all ages can suffer from Henoch-Schönlein purpura (HSP), but it is the most common vasculitis in childhood. The most important involving gene is located on chromosome 6p21.3, a region coding for human leukocyte antigens (HLAs). Among HLA genes, because of the high rate of polymorphisms, HLA-DRB1 is estimated to have a strong association with HSP. In this study, we aimed to assess the association of HLA-DRB1 alleles with HSP in Iranian children. Materials and Methods: This study consisted of thirty Iranian children with HSP and 35 healthy controls...
2018: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/29937903/medical-diagnostic-self-examination-application-applied-medical-informatics-technology-for-supporting-primary-self-care
#8
Beuy Joob, Viroj Wiwanitkit
No abstract text is available yet for this article.
2018: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/29937902/doppler-assessment-of-children-with-liver-cirrhosis-and-portal-hypertension-in-comparison-with-a-healthy-control-group-an-analytical-cross-sectional-study
#9
Maryam Riahinezhad, Mohammadreza Rezaei, Hosein Saneian, Fatemeh Famouri, Maryam Farghadani
Background: Doppler ultrasonography (Doppler US) plays an important role in evaluating patients with liver cirrhosis. This study aims to investigate the hemodynamic alterations of hepatic artery and portal vein among children with liver cirrhosis and portal hypertension (esophageal varices). Materials and Methods: We conducted an analytical cross-sectional study in Imam Hossein Children's Hospital, Isfahan, Iran, in 2016. A number of 33 cirrhotic children with or without esophageal varices were selected through convenience sampling method to be compared with 19 healthy children as controls using color and spectral Doppler US...
2018: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/29937901/serum-procollagen-type-1-n-propeptide-a-novel-diagnostic-test-for-diabetic-foot-osteomyelitis-a-case-control-study
#10
Oliver G Hayes, Venkat N Vangaveti, Usman H Malabu
Background: The objective of the study was to determine whether serum levels of procollagen type 1 N propeptide (P1NP), a bone formation turnover marker, differs between diabetic foot ulcer with osteomyelitis (DFO) and diabetic foot ulcers without osteomyelitis serving as controls. It was also aimed to assess the usefulness of P1NP in diagnosing DFO compared to other common inflammatory markers. Materials and Methods: A case-control study was designed comparing the aforementioned groups...
2018: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/29887906/ultrasonographic-findings-of-rheumatoid-arthritis-patients-who-are-in-clinical-remission
#11
Hadi Karimzadeh, Mehdi Karami, Nasrin Bazgir, Mansour Karimifar, Ghasem Yadegarfar, Zohrea Mohammadzadeh
Background: The aim of this study was to recognize the findings of ultrasonography (US) in remitted rheumatic arthritis (RA) patients for detection subclinical arthritis. Materials and Methods: This descriptive study was conducted during 2016 in a rheumatology center. A total of 70 patients with remitted RA were included in the study. Sonography was performed on all 70 patients who did not show any clinical arthritis in clinical examination to find synovitis and effusion were evaluated with gray scale and hyperemia with power Doppler US...
2018: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/29887905/effectiveness-of-extracorporeal-shockwave-therapy-for-chronic-achilles-tendinopathy-a-randomized-clinical-trial
#12
Babak Vahdatpour, Hadi Forouzan, Fatemeh Momeni, Mehdi Ahmadi, Parisa Taheri
Background: In this study, we aimed to evaluate the effectiveness of extracorporeal shockwave treatment (ESWT) on pain and ankle-hindfoot scale of the American Orthopedic Foot and Ankle Society (AOFAS) score of patients with chronic Achilles tendinopathy (AT). Materials and Methods: In this double-blind clinical trial, 43 patients with chronic AT were selected and randomly allocated in two groups to receive a basic treatment with ESWT or sham SWT (radial and focused shock waves, four sessions once a week for 4 weeks)...
2018: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/29887904/immunology-and-genetic-of-leishmania-infantum-the-role-of-endonuclease-g-in-the-apoptosis
#13
REVIEW
Mehdi Azami, Vahid Ranjkesh Adermanabadi, Hossein Khanahmad, Mohammad Ali Mohaghegh, Ebtesam Zaherinejad, Maryam Aghaei, Akram Jalali, Seyed Hossein Hejazi
Leishmania infantum is the causative agent of infantile visceral leishmaniasis (VL) in the Mediterranean region. Despite developing protective responses, the disease progresses due to many of factors. These include the action of suppressive cytokines, exhaustion of specific T cells, loss of lymphoid tissue, and defective humoral response. Genetic changes that occur inside the genome of alienated or parasite cells, along with immune responses, play an important role in controlling or progressing the disease...
2018: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/29887903/the-prognostic-value-of-lymph-node-ratio-in-survival-of-head-and-neck-squamous-cell-carcinoma
#14
Reza Eshraghi Samani, Mohammad Shirkhoda, Maryam Hadji, Faramarz Beheshtifard, Seyed Mohammad Mehdi Ghaffari Hamedani, Ali Momen, Mahtab Mollashahi, Kazem Zendehdel
Background: Head-and-neck squamous cell carcinoma (HNSCC) is the sixth most prevalent type of cancers in the world. Due to its relatively high rate of recurrence, the prognosis of patients is poor and the survival rate is low; therefore, identifying the prognostic factors is considered necessary for better treatment. Materials and Methods: This historical cohort study was conducted on 201 patients diagnosed with aerodigestive SCC who underwent surgery and lymph node dissection...
2018: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/29887902/mathematical-modeling-for-hemoglobin-change-due-to-blood-loss-due-to-hookworm-infection
#15
Sora Yasri, Viroj Wiwanitkit
No abstract text is available yet for this article.
2018: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/29887901/effect-of-chamomile-capsule-on-lipid-and-hormonal-related-parameters-among-women-of-reproductive-age-with-polycystic-ovary-syndrome
#16
Maryam Heidary, Zahra Yazdanpanahi, Mohammad Hossain Dabbaghmanesh, Mohammad Ebrahin Parsanezhad, Masoumeh Emamghoreishi, Marzieh Akbarzadeh
Background: According to traditional herbal medicine, chamomile has been considered as one of the herbal remedies for patients with polycystic ovary syndrome (PCOS). The study aimed to investigate the effect of chamomile on lipid and hormonal parameters in women of reproductive age with PCOS. Materials and Methods: This study is a randomized clinical trial which was conducted on 80 women (40 patients in each group) of childbearing age with PCO. The intervention group received 370 mg oral capsules of chamomile three times a day for 3 months...
2018: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/29887900/effect-of-fermented-camel-milk-on-glucose-metabolism-insulin-resistance-and-inflammatory-biomarkers-of-adolescents-with-metabolic-syndrome-a-double-blind-randomized-crossover-trial
#17
Zahra Fallah, Awat Feizi, Mahin Hashemipour, Roya Kelishadi
Background: This study, for the first time, aimed to assess the effects of fermented camel milk (FCM) on glycemic and inflammatory parameters related to metabolic syndrome (MetS), an aggregation of cardiometabolic risk factors, in adolescents. Materials and Methods: In a double-blind, randomized crossover trial, overweight/obese adolescents (fulfilling MetS criteria, aged 11-18 years) were randomly assigned to receive FCM 250 cc per day for an 8-week period, a 4-week washout, and then diluted cow's yogurt (DCY) 250 cc/day for another 8-week period, or the reverse sequence...
2018: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/29887899/comparison-of-salivary-testosterone-levels-in-different-phases-of-bipolar-i-disorder-and-control-group
#18
Sabra Mousavizadegan, Mohsen Maroufi
Background: Testosterone is considered as a primary sex hormone, also known as an important anabolic steroid, that may involve in various mental disorders such as bipolar I disorder (BID). The goal of this study was to compare the testosterone salivary levels between different phases of BID and its association with the clinical features of BID. Materials and Methods: In a case-control study, 15 patients in the mania phase, 10 patients in the depression phase, and 16 in the euthymia phase were selected as patient groups...
2018: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/29887898/endotracheal-stent-increased-survival-length-in-patients-with-invasive-thymic-adenocarcinoma
#19
Tatjana Adzic-Vukicevic, Aleksandra Barac, Ana Blanka-Protic, Spasoje Popovic, Zivka Uskokovic-Stefanovic, Jelena Stojsic, Aleksandra Dudvarski Ilic
We reported the first case of inoperative thymic adenocarcinoma successfully palliative treated by the double-stent procedure. In a patient who expressed stridor, computed tomography was done and necrotic mediastinal mass, which protrudes into a trachea, was demonstrated. Fiberoptic bronchoscopy showed tracheal infiltration and 70% stenosis; therefore, surgical resection was inapplicable. Recanalization with repeated argon plasma coagulation and debridement of necrotic mass was performed, followed by placement of the endotracheal stent, radiotherapy, and chemotherapy...
2018: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/29887897/varicella-infection-in-the-middle-east-prevalence-complications-and-vaccination
#20
REVIEW
Mariam Al-Turab, Wassim Chehadeh
Varicella (chickenpox) is the primary infection of varicella-zoster virus (VZV), it is a mild self-limiting infection, but it is also highly contagious and can cause severe complications among high-risk group of individuals. It is usually a childhood infection providing lifelong immunity, but adults without varicella history are also susceptible to infection. High-risk group of individuals is more likely to develop serious complications. Varicella vaccine was introduced to protect this group of individuals and to prevent epidemic spread of VZV infection in a community...
2018: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
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